PICRUSt Stratified Analyses

Campylobacter concisus

workflowr

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Last updated: 2021-04-15

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Knit directory: esoph-micro-cancer-workflow/

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i. Mean relative abundance in Tumors

ii. Standard error of mean in Tumors

iii. Mean relative abundance in Non-tumors

iv. Standard error of mean in Non-tumors

v. GLM differential abundance analysis between Tumor vs Non-tumor (Patient=Fixed effect)
  1. P-value
  2. FDR corrected q-value
vi. GLMM differential abundance analysis between Tumor vs Non-tumor (Patient=Random Effect)
  1.P-value
  2. FDR corrected q-value

Part 1 EC Data

# note: must rename function to func (or something else) because "function" is a reserved name in R and can't be used.

descriptions <- readr::read_tsv("data/PICRUST/ec_pred_metagenome_unstrat_descrip.tsv")[,1:2] %>%
  distinct()

-- Column specification --------------------------------------------------------
cols(
  .default = col_double(),
  `function` = col_character(),
  description = col_character()
)
i Use `spec()` for the full column specifications.

colnames(descriptions) <- c("func", "description")

pi.dat <- readxl::read_xlsx("data/PICRUST-Stratified/EC_campy.xlsx")
colnames(pi.dat) <- c("func",  colnames(pi.dat)[-c(1)])

# add descriptions to dataframe
pi.dat <- left_join(pi.dat, descriptions, by="func")
pi.dat <- pi.dat[,c(1,161,3:160)]

# aggregate descriptions to get 1 description per row - unique;y defined.
pi.dat <- pi.dat %>%
  group_by(description) %>%
  summarise(across(`1.S37.Jun172016`:`99.D01.S37.Jun232016`,.fns = mean))

# make long format
pi.dat <- pi.dat %>%
  pivot_longer(
    cols=`1.S37.Jun172016`:`99.D01.S37.Jun232016`,
    names_to = "ID",
    values_to = "Abundance"
  )
d <- as.data.frame(dat.16s)
mydata <- full_join(pi.dat, d)

Joining, by = "ID"

Warning in class(x) <- c(setdiff(subclass, tibble_class), tibble_class): Setting
class(x) to multiple strings ("tbl_df", "tbl", ...); result will no longer be an
S4 object

mydata <- mydata %>%
  mutate(
    ID.n = as.numeric(as.factor(ID)),
    description.n = as.numeric(as.factor(description))
  ) %>%
  group_by(description)%>%
  mutate(avgA = mean(Abundance))

Abundance

I needed to change from relative abundance to abundance due to so many individuals having 0 counts for all descriptions.

d <- mydata %>%
  filter(description=="DNA-directed DNA polymerase")

t.test(d$Abundance ~ d$tumor.cat)

    Welch Two Sample t-test

data:  d$Abundance by d$tumor.cat
t = -0.649, df = 141, p-value = 0.52
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
 -6.6450  3.3603
sample estimates:
mean in group Non-Tumor     mean in group Tumor 
                 3.5269                  5.1692 

# Run on all descriptions
tb.ra1 <- mydata %>%
  group_by(description) %>%
  summarise(ng = n(),
            Overall.M = mean(Abundance),
            Overall.SE = sd(Abundance)/sqrt(ng))
tb.ra2m <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(M = mean(Abundance)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = M)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2se <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n(),SE = sd(Abundance)/sqrt(ng)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = SE)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2var <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n(), VAR = var(Abundance)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = VAR)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2ng <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n()) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = ng)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra <- left_join(tb.ra1, tb.ra2m)

Joining, by = "description"

tb.ra <- cbind(tb.ra, tb.ra2se[,-1])
tb.ra <- cbind(tb.ra, tb.ra2var[,-1])
tb.ra <- cbind(tb.ra, tb.ra2ng[,-1]) 

colnames(tb.ra) <- c("description", "ng", "Overall Mean", "Overall SE", "Non-Tumor Mean", "Tumor Mean", "Non-Tumor SE", "Tumor SE","Non-Tumor Var", "Tumor Var", "Non-Tumor Ng", "Tumor Ng")
tb.ra <- tb.ra %>%
  arrange(desc(`Overall Mean`))
tb.ra <- tb.ra[, c("description", "Overall Mean", "Overall SE","Tumor Mean","Tumor Var", "Tumor SE","Tumor Ng", "Non-Tumor Mean","Non-Tumor Var", "Non-Tumor SE", "Non-Tumor Ng")]

# compute t-test
tb.ra <- tb.ra %>%
  mutate(
    SEpooled = sqrt(`Tumor Var`/`Tumor Ng` + `Non-Tumor Var`/`Non-Tumor Ng`),
    t = (`Tumor Mean` - `Non-Tumor Mean`)/(SEpooled),
    df = ((`Tumor Var`/`Tumor Ng` + `Non-Tumor Var`/`Non-Tumor Ng`)**2)/(((`Tumor Var`/`Tumor Ng`)**2)/(`Tumor Ng`-1) + ((`Non-Tumor Var`/`Non-Tumor Ng`)**2)/(`Non-Tumor Ng`-1)),
    p = pt(q = abs(t), df=df, lower.tail = F)*2,
    fdr_p = p.adjust(p, method="fdr")
  )



kable(tb.ra, format="html", digits=5, caption="Stratefied EC Data - Campylobacter concisus: Average Abundance of Each Description (sorted in descending order)") %>%
  kable_styling(full_width = T) %>%
  scroll_box(width = "100%", height="600px")

Stratefied EC Data - Campylobacter concisus: Average Abundance of Each Description (sorted in descending order)

description	Overall Mean	Overall SE	Tumor Mean	Tumor Var	Tumor SE	Tumor Ng	Non-Tumor Mean	Non-Tumor Var	Non-Tumor SE	Non-Tumor Ng	SEpooled	t	df	p	fdr_p
NADH:ubiquinone reductase (H(+)-translocating)	5.25316	1.56480	6.46154	370.096	2.38617	65	4.40860	401.005	2.07651	93	3.16317	0.64901	141.28	0.51738	0.51738
DNA-directed DNA polymerase	4.20253	1.25184	5.16923	236.862	1.90893	65	3.52688	256.643	1.66121	93	2.53054	0.64901	141.28	0.51738	0.51738
Formate dehydrogenase	4.20253	1.25184	5.16923	236.862	1.90893	65	3.52688	256.643	1.66121	93	2.53054	0.64901	141.28	0.51738	0.51738
Histidine kinase	3.67722	1.09536	4.52308	181.347	1.67032	65	3.08602	196.493	1.45356	93	2.21422	0.64901	141.28	0.51738	0.51738
DNA helicase	3.15190	0.93888	3.87692	133.235	1.43170	65	2.64516	144.362	1.24590	93	1.89790	0.64901	141.28	0.51738	0.51738
Peptidylprolyl isomerase	2.62658	0.78240	3.23077	92.524	1.19308	65	2.20430	100.251	1.03825	93	1.58159	0.64901	141.28	0.51738	0.51738
2-oxoglutarate synthase	2.10127	0.62592	2.58462	59.215	0.95447	65	1.76344	64.161	0.83060	93	1.26527	0.64901	141.28	0.51738	0.51738
Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	2.10127	0.62592	2.58462	59.215	0.95447	65	1.76344	64.161	0.83060	93	1.26527	0.64901	141.28	0.51738	0.51738
DNA-directed RNA polymerase	2.10127	0.62592	2.58462	59.215	0.95447	65	1.76344	64.161	0.83060	93	1.26527	0.64901	141.28	0.51738	0.51738
Fumarate reductase (quinol)	2.10127	0.62592	2.58462	59.215	0.95447	65	1.76344	64.161	0.83060	93	1.26527	0.64901	141.28	0.51738	0.51738
Site-specific DNA-methyltransferase (adenine-specific)	2.10127	0.62592	2.58462	59.215	0.95447	65	1.76344	64.161	0.83060	93	1.26527	0.64901	141.28	0.51738	0.51738
Trimethylamine-N-oxide reductase (cytochrome c)	2.10127	0.62592	2.58462	59.215	0.95447	65	1.76344	64.161	0.83060	93	1.26527	0.64901	141.28	0.51738	0.51738
23S rRNA pseudouridine(1911/1915/1917) synthase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Acetyl-CoA carboxylase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Asparaginase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Asparaginyl-tRNA synthase (glutamine-hydrolyzing)	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Fumarate hydratase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Glutamate–tRNA ligase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Glutaminyl-tRNA synthase (glutamine-hydrolyzing)	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
H(+)-transporting two-sector ATPase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Hydroxymethylpyrimidine kinase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Peroxiredoxin	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Phosphomethylpyrimidine kinase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Phosphoribosylformylglycinamidine synthase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Ribonucleoside-diphosphate reductase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Thiamine-phosphate diphosphorylase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
Threonine synthase	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
(R)-2-methylmalate dehydratase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
1,4-N-acetyl-D-galactosaminyltransferase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
2-hydroxymuconate tautomerase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
2-isopropylmalate synthase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
2-oxoacid oxidoreductase (ferredoxin)	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
3-isopropylmalate dehydratase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
3-oxoacyl-[acyl-carrier-protein] reductase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
4-hydroxy-3-polyprenylbenzoate decarboxylase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
4-hydroxy-tetrahydrodipicolinate synthase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Acetolactate synthase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Anthranilate synthase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Aryl-sulfate sulfotransferase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Assimilatory sulfite reductase (NADPH)	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Beta-ketoacyl-[acyl-carrier-protein] synthase II	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Coproporphyrinogen dehydrogenase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Cu(+) exporting ATPase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Cyclic pyranopterin phosphate synthase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Cystathionine beta-lyase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Dipeptidase E	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
DNA topoisomerase (ATP-hydrolyzing)	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Exodeoxyribonuclease VII	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Exopolyphosphatase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Ferrochelatase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Glycerol-3-phosphate 1-O-acyltransferase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Glycine–tRNA ligase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
GTP cyclohydrolase II	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Guanosine-5’-triphosphate,3’-diphosphate diphosphatase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Hydrogen:quinone oxidoreductase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Iron-chelate-transporting ATPase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
L(+)-tartrate dehydratase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Molybdopterin molybdotransferase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Pectate lyase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Phenylalanine–tRNA ligase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Phosphatidylserine decarboxylase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Phosphoglycolate phosphatase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Polar-amino-acid-transporting ATPase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Pyruvate carboxylase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Ribonuclease H	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Succinate dehydrogenase (quinone)	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Superoxide dismutase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Thioredoxin-disulfide reductase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Tryptophan synthase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Type I site-specific deoxyribonuclease	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
Undecaprenyl-diphosphooligosaccharide–protein glycotransferase	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
(2E,6E)-farnesyl diphosphate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
(Kdo)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
(Kdo)(2)-lipid IV(A) (2-8) 3-deoxy-D-manno-octulosonic acid transferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
(Kdo)(3)-lipid IV(A) (2-4) 3-deoxy-D-manno-octulosonic acid transferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
[Acyl-carrier-protein] S-malonyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
[Formate-C-acetyltransferase]-activating enzyme	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
[Protein-PII] uridylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
1-acylglycerol-3-phosphate O-acyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
1-aminocyclopropane-1-carboxylate deaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
1-deoxy-D-xylulose-5-phosphate reductoisomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
1-deoxy-D-xylulose-5-phosphate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
16S rRNA (cytidine(1402)-2’-O)-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
16S rRNA (cytidine(1409)-2’-O)-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
16S rRNA (cytosine(1402)-N(4))-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
16S rRNA (guanine(527)-N(7))-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
16S rRNA (uracil(1498)-N(3))-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
2-iminoacetate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
2-iminobutanoate/2-iminopropanoate deaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
2-methylisocitrate dehydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
23S rRNA (adenine(2503)-C(2))-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
23S rRNA (cytidine(1920)-2’-O)-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
23S rRNA (guanosine(2251)-2’-O)-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
23S rRNA pseudouridine(2605) synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
23S rRNA pseudouridine(955/2504/2580) synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3’(2’),5’-bisphosphate nucleotidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-dehydroquinate dehydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-dehydroquinate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-deoxy-7-phosphoheptulonate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-deoxy-8-phosphooctulonate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-deoxy-manno-octulosonate-8-phosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-deoxy-manno-octulosonate cytidylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-hydroxyacyl-[acyl-carrier-protein] dehydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-isopropylmalate dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-methyl-2-oxobutanoate hydroxymethyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3-phosphoshikimate 1-carboxyvinyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
3,4-dihydroxy-2-butanone-4-phosphate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
4-alpha-N-acetylgalactosaminyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
4-hydroxy-tetrahydrodipicolinate reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
4-hydroxybenzoate polyprenyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
5’-nucleotidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
5’ to 3’ exodeoxyribonuclease (nucleoside 3’-phosphate-forming)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
5-(carboxyamino)imidazole ribonucleotide mutase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
5-amino-6-(5-phosphoribosylamino)uracil reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
5-formyltetrahydrofolate cyclo-ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
5-methyltetrahydropteroyltriglutamate–homocysteine S-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
6-carboxytetrahydropterin synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
6-pyruvoyltetrahydropterin 2’-reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
6-pyruvoyltetrahydropterin synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
6,7-dimethyl-8-ribityllumazine synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
7-alpha-hydroxysteroid dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
7-cyano-7-deazaguanine synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Acetate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
acetylgalactosaminyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
acetylglucosaminyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aconitate hydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Acyl-[acyl-carrier-protein]–phospholipid O-acyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Acyl-[acyl-carrier-protein]–UDP-N-acetylglucosamine O-acyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Adenine phosphoribosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Adenosylhomocysteine nucleosidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Adenylate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Adenylosuccinate lyase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Adenylosuccinate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ADP-glyceromanno-heptose 6-epimerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Alanine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Alanine racemase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
All-trans-octaprenyl-diphosphate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Amidophosphoribosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aminoacyl-tRNA hydrolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aminodeoxyfutalosine nucleosidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aminodeoxyfutalosine synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Anthranilate phosphoribosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Arabinose-5-phosphate isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Arginine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Arginine decarboxylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Argininosuccinate lyase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Argininosuccinate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Asparagine synthase (glutamine-hydrolyzing)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aspartate–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aspartate-semialdehyde dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aspartate 1-decarboxylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aspartate ammonia-lyase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aspartate carbamoyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aspartate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aspartate racemase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Aspartate transaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ATP phosphoribosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Beta-ketoacyl-[acyl-carrier-protein] synthase I	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Beta-ketoacyl-[acyl-carrier-protein] synthase III	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Beta-N-acetylhexosaminidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Biotin–[acetyl-CoA-carboxylase] ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Biotin carboxylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Biotin synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Branched-chain-amino-acid transaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
C-terminal processing peptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Carbonate dehydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Carboxynorspermidine decarboxylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CCA tRNA nucleotidyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CDP-diacylglycerol–glycerol-3-phosphate 3-phosphatidyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CDP-diacylglycerol–serine O-phosphatidyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Chorismate dehydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Chorismate mutase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Chorismate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Citrate (Si)-synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CMP-N,N’-diacetyllegionaminic acid synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Crossover junction endodeoxyribonuclease	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CTP synthase (glutamine hydrolyzing)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Cyclic dehypoxanthinyl futalosine synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Cysteine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Cysteine desulfurase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Cysteine synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Cytochrome-c oxidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Cytochrome-c peroxidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
D-alanine–D-alanine ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
D-amino-acid transaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
D-glycero-beta-D-manno-heptose-7-phosphate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
D-sedoheptulose 7-phosphate isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dCTP deaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Demethylmenaquinone methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Deoxyribonuclease IV	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Dephospho-CoA kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Diacylglycerol kinase (ATP)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Diaminohydroxyphosphoribosylaminopyrimidine deaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Diaminopimelate decarboxylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Diaminopimelate epimerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Dihydrofolate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Dihydroneopterin aldolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Dihydroorotase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Dihydroorotate dehydrogenase (quinone)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Dihydropteroate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Dihydroxy-acid dehydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Dimethylallyltranstransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
diphosphate specific)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNA-(apurinic or apyrimidinic site) lyase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNA-3-methyladenine glycosylase I	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNA (cytosine-5-)-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNA ligase (ATP or NAD(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNA ligase (ATP)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNA ligase (ATP, ADP or GTP)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNA ligase (NAD(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNA topoisomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dTMP kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Endopeptidase Clp	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Endopeptidase La	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Enoyl-[acyl-carrier-protein] reductase (NADH)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Exodeoxyribonuclease III	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Exodeoxyribonuclease V	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
FAD synthetase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Feruloyl esterase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Formate–tetrahydrofolate ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Formate dehydrogenase (NADP(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Fructose-bisphosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Fructose-bisphosphate aldolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GalNAc(5)-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glucosamine-1-phosphate N-acetyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glucose-6-phosphate isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glutamate–ammonia ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glutamate-1-semialdehyde 2,1-aminomutase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glutamate carboxypeptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glutamate dehydrogenase (NAD(P)(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glutamate dehydrogenase (NADP(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glutamate racemase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glutamine–fructose-6-phosphate transaminase (isomerizing)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glutamyl-tRNA reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glycerate 3-kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glycerate dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glycerol-3-phosphate dehydrogenase (NAD(P)(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Glycine hydroxymethyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GMP synthase (glutamine-hydrolyzing)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GTP cyclohydrolase I	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GTP diphosphokinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Guanylate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Histidine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Histidinol-phosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Histidinol-phosphate transaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Histidinol dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Holo-[acyl-carrier-protein] synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Homoserine dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Homoserine kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Homoserine O-acetyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
HslU–HslV peptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
HycI peptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Hydroxylamine reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Hydroxymethylbilane synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Imidazoleglycerol-phosphate dehydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
IMP cyclohydrolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
IMP dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Indole-3-glycerol-phosphate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Inorganic diphosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Isocitrate dehydrogenase (NADP(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Isoleucine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Kdo(2)-lipid IV(A) lauroyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Ketol-acid reductoisomerase (NADP(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
L-fuculose-phosphate aldolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
L-seryl-tRNA(Sec) selenium transferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Leucine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Leucyl aminopeptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Lipid-A-disaccharide synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Long-chain-fatty-acid–[acyl-carrier-protein] ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Long-chain-fatty-acid–CoA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Lysine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Malate dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Malate dehydrogenase (quinone)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Methenyltetrahydrofolate cyclohydrolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Methionine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Methionine adenosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Methionyl-tRNA formyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Methionyl aminopeptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Methylated-DNA–[protein]-cysteine S-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Methylenetetrahydrofolate dehydrogenase (NADP(+))	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Molybdate-transporting ATPase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Molybdenum cofactor guanylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Molybdopterin adenylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Molybdopterin synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
N-acetylmuramoyl-L-alanine amidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
N-acylneuraminate cytidylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
N-carbamoyl-L-amino-acid hydrolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
N-carbamoylputrescine amidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
N(6)-L-threonylcarbamoyladenine synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
N,N’-diacetyllegionaminate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
NAD(+) kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
NAD(+) synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
NADPH dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nicotinamide-nucleotide amidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nicotinate-nucleotide adenylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nicotinate phosphoribosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nitrate reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nitric-oxide reductase (cytochrome c)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nitrilase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nitronate monooxygenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nitrous-oxide reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Nucleoside-diphosphate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
O-acetylhomoserine aminocarboxypropyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Ornithine carbamoyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Orotate phosphoribosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Orotidine-5’-phosphate decarboxylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Pantetheine-phosphate adenylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Pantoate–beta-alanine ligase (AMP-forming)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Pantothenate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Peptidase Do	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Peptide-methionine (R)-S-oxide reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Peptide-methionine (S)-S-oxide reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Peptide chain release factor N(5)-glutamine methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Peptide deformylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphate acetyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphatidate cytidylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphatidylglycerophosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphinothricin acetyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phospho-N-acetylmuramoyl-pentapeptide-transferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoenolpyruvate carboxykinase (ATP)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoglucosamine mutase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoglycerate dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoglycerate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoglycerate mutase (2,3-diphosphoglycerate-independent)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phospholipase A(1)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phospholipase A(2)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphomannomutase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphomethylpyrimidine synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphopantothenate–cysteine ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphopantothenoylcysteine decarboxylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphopyruvate hydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoribosyl-AMP cyclohydrolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoribosyl-ATP diphosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoribosylamine–glycine ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoribosylaminoimidazolecarboxamide formyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoribosylaminoimidazolesuccinocarboxamide synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoribosylanthranilate isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoribosylformylglycinamidine cyclo-ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoribosylglycinamide formyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoserine phosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Phosphoserine transaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Polyphosphate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Polyribonucleotide nucleotidyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Porphobilinogen synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Prephenate dehydratase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Prephenate dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Prepilin peptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PreQ(1) synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Proline–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Protein-disulfide reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Protein-glutamate methylesterase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Protein-glutamate O-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Protein-L-isoaspartate(D-aspartate) O-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Protein-serine/threonine phosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Protein disulfide-isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Pseudaminic acid cytidylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Pseudaminic acid synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Pyridoxal kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Pyruvate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Pyruvate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Quinol–cytochrome-c reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Riboflavin kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Riboflavin synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Ribonuclease III	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Ribonucleoside-triphosphate reductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Ribose-5-phosphate isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Ribose-phosphate diphosphokinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Ribulose-phosphate 3-epimerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
S-adenosylmethionine:tRNA ribosyltransferase-isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
S-ribosylhomocysteine lyase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Saccharopine dehydrogenase (NAD(+), L-lysine-forming)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Selenide, water dikinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Serine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Serine O-acetyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Shikimate dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Shikimate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Signal peptidase I	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Signal peptidase II	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Ste24 endopeptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Succinyl-diaminopimelate desuccinylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Sulfate adenylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Sulfur carrier protein ThiS adenylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Tetraacyldisaccharide 4’-kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Tetrahydrofolate synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Thiamine-phosphate kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Thiazole synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Threonine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Threonine ammonia-lyase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Thymidylate synthase (FAD)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Transaldolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
transferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Transketolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Triose-phosphate isomerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Tripeptide aminopeptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA-guanine(34) transglycosylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA (cytidine(34)-2’-O)-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA (guanine(37)-N(1))-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA (guanine(46)-N(7))-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA (uracil(54)-C(5))-methyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA dimethylallyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA pseudouridine(13) synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA pseudouridine(38-40) synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA pseudouridine(55) synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tRNA(Ile)-lysidine synthetase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Tryptophan–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Tungstate-importing ATPase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Tyrosine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-2,3-diacylglucosamine diphosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-3-O-acyl-N-acetylglucosamine deacetylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-glucose 4-epimerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-glucose 6-dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-glucuronate 4-epimerase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylbacillosamine N-acetyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylbacillosamine transaminase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylglucosamine diphosphorylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylmuramate–L-alanine ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylmuramate dehydrogenase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylmuramoyl-L-alanine–D-glutamate ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N-acetylmuramoyl-tripeptide–D-alanyl-D-alanine ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-N,N’-diacetylbacillosamine 2-epimerase (hydrolyzing)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UDP-sugar diphosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UMP kinase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Undecaprenyl-diphosphate phosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Uracil-DNA glycosylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Uracil phosphoribosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Uroporphyrinogen-III synthase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Uroporphyrinogen decarboxylase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UTP–glucose-1-phosphate uridylyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Valine–tRNA ligase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Xaa-Pro aminopeptidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
Xanthine phosphoribosyltransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
XTP/dITP diphosphatase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738

plot.dat <- tb.ra %>%
  arrange(p) %>%
  slice_head(n=50)%>%
  mutate(
    description = fct_reorder(description, `Overall Mean`),
    description = factor(description, levels = levels(description), ordered=T)
  ) %>%
  arrange(description) %>%
  mutate(
    id = 1:n(),
    step = ifelse(id%%2 == 0, 1, 0),
    Mean_diff = `Tumor Mean` - `Non-Tumor Mean`,
    diff_se = SEpooled,
    Mean_diff_ll = Mean_diff - qt(0.975, df)*diff_se,
    Mean_diff_ul = Mean_diff + qt(0.975, df)*diff_se
  ) %>%
  pivot_longer(
    cols=contains("Mean"),
    names_to = "group",
    values_to = "mean"
  )



p1.d <- plot.dat %>%
  filter(group %in% c("Tumor Mean","Non-Tumor Mean")) %>%
  mutate(
    group = ifelse(group == "Tumor Mean", "Tumor", "Non-Tumor"),
    col = ifelse(step == 1, "grey90", "white"),
    h=1, w=Inf
    
  )
p1 <- ggplot()+
  geom_tile(data = p1.d,
              aes(y = description, x=0,
                  height=h, width=w),
              fill = p1.d$col, color=p1.d$col)+
    geom_bar(data=p1.d,
             aes(x=mean, y=description,
                 group=group, color=group,
                 fill=group),
             stat="identity",position = "dodge",
             alpha = 1)+
    labs(x="Mean Abundance")+
    theme_classic()+
    theme(
      legend.position = "bottom",
      plot.margin = unit(c(1,0,1,1), "lines")
    )

p2.d <- plot.dat %>%
  filter(group %in% c("Mean_diff", "Mean_diff_ll", "Mean_diff_ul")) %>%
  pivot_wider(
    names_from = group,
    values_from = mean
  ) %>%
  mutate(
    group = ifelse(Mean_diff > 0, "Tumor", "Non-Tumor"),
    p = sprintf("%.3f", round(p,3)),
    ll = min(Mean_diff_ll)-0.01,
    ul = max(Mean_diff_ul)+0.01
  )
p2<-ggplot(p2.d, aes(x=Mean_diff, y=description))+
    geom_tile(data = p1.d,
              aes(y = description, x=0,
                  height=h, width=w),
              fill = p1.d$col, color=p1.d$col)+
    geom_vline(xintercept = 0, linetype="dashed", alpha=0.5)+
    geom_segment(aes(x=Mean_diff_ll, y=description, xend=Mean_diff_ul, yend=description))+
    geom_point(aes(fill=group, color=group))+
    geom_text(aes(label=p, x=unique(ul)+0.1))+
    coord_cartesian(xlim = c(unique(p2.d$ll), unique(p2.d$ul)),
                    clip = 'off') +
    annotate("text", x=unique(p2.d$ul)+0.2,y = 25,
             angle=90,
             label="p-value (uncorrected)")+
    labs(x="Mean Difference in Abundance")+
    theme_classic()+
    theme(
      legend.position = "bottom",
      axis.title.y = element_blank(),
      axis.text.y = element_blank(),
      axis.line.y = element_blank(),
      axis.ticks.y = element_blank(),
      plot.margin = unit(c(1,4,1,0), "lines")
    )

# plot
p1 + p2 +
  plot_annotation(title="Stratefied EC Data - Campylobacter concisus: First 50 descriptions with lowest p-value (uncorrected)")

Modeling Difference between Tumor and Non-Tumor

For the modeling, we used a generalized linear mixed model (GLMM).

First, we looked at the biserial correlation between the abundance of each description and the tumor status.

tb <- mydata %>%
  group_by(description)%>%
  summarise(
    r = cor(tumor, Abundance)
  ) %>%
  mutate(
    M=mean(r)
  )

ggplot(tb, aes(x=r))+
  geom_density()+
  geom_vline(aes(xintercept = M))+
  labs(x="Biserial Correlation",title="Relationship between description abundance and tumor (tumor vs. non-tumor)")+
  theme(panel.grid = element_blank())

Next, we need the data to be on an interpretable scale. First, let’s use the raw abundance like scale.

p <- ggplot(mydata, aes(x=Abundance))+
  geom_density()
p

mydata <- mydata %>%
  mutate(Abundance.dich=ifelse(Abundance==0, 0, 1))
table(mydata$Abundance.dich)

    0     1 
61908 11088 

Let’s first run models by description so that we can avoid the nesting issue initially. We will come back to this to conduct the final model (it will be more powerful).

DESCRIPTIONS <- unique(mydata$description)
i<-1
dat0 <- mydata %>% filter(description==DESCRIPTIONS[i])

# quasipossion (approximately negative binom) give an approx. answer.
fit0 <- glm(
  Abundance ~ 1 + tumor,
  data= dat0,
  family=quasipoisson(link = "log")
)
summary(fit0)

Call:
glm(formula = Abundance ~ 1 + tumor, family = quasipoisson(link = "log"), 
    data = dat0)

Deviance Residuals: 
   Min      1Q  Median      3Q     Max  
-1.137  -1.137  -0.939  -0.939   9.542  

Coefficients:
            Estimate Std. Error t value Pr(>|t|)  
(Intercept)   -0.819      0.434   -1.89    0.061 .
tumor          0.382      0.610    0.63    0.532  
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

(Dispersion parameter for quasipoisson family taken to be 7.7141)

    Null deviance: 387.36  on 157  degrees of freedom
Residual deviance: 384.34  on 156  degrees of freedom
AIC: NA

Number of Fisher Scoring iterations: 7

Run over all descriptors

results.out <- as.data.frame(matrix(ncol=4, nrow=length(DESCRIPTIONS)))
colnames(results.out) <- c("description", "Est", "SE", "p")
#results.out$description <-DESCRIPTIONS

i <- 1
for(i in 1:length(DESCRIPTIONS)){
#for(i in 1:5){ 
  dat0 <- mydata %>%
    filter(description == DESCRIPTIONS[i])
  fit0 <- glm(
  Abundance ~ 1 + tumor,
  data= dat0,
  family=quasipoisson(link = "log")
)
  fit.sum <- summary(fit0)
  results.out[i, 1] <- DESCRIPTIONS[i]
  results.out[i, 2:4] <- fit.sum$coefficients[2, c(1,2,4)]
}

results.out$fdr_p <- p.adjust(results.out$p, method="fdr")

kable(results.out, format="html", digits=3) %>%
  kable_styling(full_width = T)%>%
  scroll_box(width="100%", height="600px")

description	Est	SE	p	fdr_p
(2E,6E)-farnesyl diphosphate synthase	0.382	0.61	0.532	0.532
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (ferredoxin)	0.382	0.61	0.532	0.532
(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase (flavodoxin)	0.382	0.61	0.532	0.532
(Kdo)-lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase	0.382	0.61	0.532	0.532
(Kdo)(2)-lipid IV(A) (2-8) 3-deoxy-D-manno-octulosonic acid transferase	0.382	0.61	0.532	0.532
(Kdo)(3)-lipid IV(A) (2-4) 3-deoxy-D-manno-octulosonic acid transferase	0.382	0.61	0.532	0.532
(R)-2-methylmalate dehydratase	0.382	0.61	0.532	0.532
[Acyl-carrier-protein] S-malonyltransferase	0.382	0.61	0.532	0.532
[Formate-C-acetyltransferase]-activating enzyme	0.382	0.61	0.532	0.532
[Protein-PII] uridylyltransferase	0.382	0.61	0.532	0.532
1-acylglycerol-3-phosphate O-acyltransferase	0.382	0.61	0.532	0.532
1-aminocyclopropane-1-carboxylate deaminase	0.382	0.61	0.532	0.532
1-deoxy-D-xylulose-5-phosphate reductoisomerase	0.382	0.61	0.532	0.532
1-deoxy-D-xylulose-5-phosphate synthase	0.382	0.61	0.532	0.532
1,4-N-acetyl-D-galactosaminyltransferase	0.382	0.61	0.532	0.532
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase	0.382	0.61	0.532	0.532
16S rRNA (cytidine(1402)-2’-O)-methyltransferase	0.382	0.61	0.532	0.532
16S rRNA (cytidine(1409)-2’-O)-methyltransferase	0.382	0.61	0.532	0.532
16S rRNA (cytosine(1402)-N(4))-methyltransferase	0.382	0.61	0.532	0.532
16S rRNA (guanine(527)-N(7))-methyltransferase	0.382	0.61	0.532	0.532
16S rRNA (uracil(1498)-N(3))-methyltransferase	0.382	0.61	0.532	0.532
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.382	0.61	0.532	0.532
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0.382	0.61	0.532	0.532
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	0.382	0.61	0.532	0.532
2-hydroxymuconate tautomerase	0.382	0.61	0.532	0.532
2-iminoacetate synthase	0.382	0.61	0.532	0.532
2-iminobutanoate/2-iminopropanoate deaminase	0.382	0.61	0.532	0.532
2-isopropylmalate synthase	0.382	0.61	0.532	0.532
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase	0.382	0.61	0.532	0.532
2-methylisocitrate dehydratase	0.382	0.61	0.532	0.532
2-oxoacid oxidoreductase (ferredoxin)	0.382	0.61	0.532	0.532
2-oxoglutarate synthase	0.382	0.61	0.532	0.532
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	0.382	0.61	0.532	0.532
23S rRNA (adenine(2503)-C(2))-methyltransferase	0.382	0.61	0.532	0.532
23S rRNA (cytidine(1920)-2’-O)-methyltransferase	0.382	0.61	0.532	0.532
23S rRNA (guanosine(2251)-2’-O)-methyltransferase	0.382	0.61	0.532	0.532
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase	0.382	0.61	0.532	0.532
23S rRNA pseudouridine(1911/1915/1917) synthase	0.382	0.61	0.532	0.532
23S rRNA pseudouridine(2605) synthase	0.382	0.61	0.532	0.532
23S rRNA pseudouridine(955/2504/2580) synthase	0.382	0.61	0.532	0.532
3’(2’),5’-bisphosphate nucleotidase	0.382	0.61	0.532	0.532
3-dehydroquinate dehydratase	0.382	0.61	0.532	0.532
3-dehydroquinate synthase	0.382	0.61	0.532	0.532
3-deoxy-7-phosphoheptulonate synthase	0.382	0.61	0.532	0.532
3-deoxy-8-phosphooctulonate synthase	0.382	0.61	0.532	0.532
3-deoxy-manno-octulosonate-8-phosphatase	0.382	0.61	0.532	0.532
3-deoxy-manno-octulosonate cytidylyltransferase	0.382	0.61	0.532	0.532
3-hydroxyacyl-[acyl-carrier-protein] dehydratase	0.382	0.61	0.532	0.532
3-isopropylmalate dehydratase	0.382	0.61	0.532	0.532
3-isopropylmalate dehydrogenase	0.382	0.61	0.532	0.532
3-methyl-2-oxobutanoate hydroxymethyltransferase	0.382	0.61	0.532	0.532
3-oxoacyl-[acyl-carrier-protein] reductase	0.382	0.61	0.532	0.532
3-phosphoshikimate 1-carboxyvinyltransferase	0.382	0.61	0.532	0.532
3,4-dihydroxy-2-butanone-4-phosphate synthase	0.382	0.61	0.532	0.532
4-(cytidine 5’-diphospho)-2-C-methyl-D-erythritol kinase	0.382	0.61	0.532	0.532
4-alpha-N-acetylgalactosaminyltransferase	0.382	0.61	0.532	0.532
4-hydroxy-3-methylbut-2-enyl diphosphate reductase	0.382	0.61	0.532	0.532
4-hydroxy-3-polyprenylbenzoate decarboxylase	0.382	0.61	0.532	0.532
4-hydroxy-tetrahydrodipicolinate reductase	0.382	0.61	0.532	0.532
4-hydroxy-tetrahydrodipicolinate synthase	0.382	0.61	0.532	0.532
4-hydroxybenzoate polyprenyltransferase	0.382	0.61	0.532	0.532
5’-nucleotidase	0.382	0.61	0.532	0.532
5’ to 3’ exodeoxyribonuclease (nucleoside 3’-phosphate-forming)	0.382	0.61	0.532	0.532
5-(carboxyamino)imidazole ribonucleotide mutase	0.382	0.61	0.532	0.532
5-amino-6-(5-phosphoribosylamino)uracil reductase	0.382	0.61	0.532	0.532
5-formyltetrahydrofolate cyclo-ligase	0.382	0.61	0.532	0.532
5-methyltetrahydropteroyltriglutamate–homocysteine S-methyltransferase	0.382	0.61	0.532	0.532
6-carboxytetrahydropterin synthase	0.382	0.61	0.532	0.532
6-pyruvoyltetrahydropterin 2’-reductase	0.382	0.61	0.532	0.532
6-pyruvoyltetrahydropterin synthase	0.382	0.61	0.532	0.532
6,7-dimethyl-8-ribityllumazine synthase	0.382	0.61	0.532	0.532
7-alpha-hydroxysteroid dehydrogenase	0.382	0.61	0.532	0.532
7-cyano-7-deazaguanine synthase	0.382	0.61	0.532	0.532
Acetate kinase	0.382	0.61	0.532	0.532
Acetolactate synthase	0.382	0.61	0.532	0.532
Acetyl-CoA carboxylase	0.382	0.61	0.532	0.532
acetylgalactosaminyltransferase	0.382	0.61	0.532	0.532
acetylglucosaminyltransferase	0.382	0.61	0.532	0.532
Aconitate hydratase	0.382	0.61	0.532	0.532
Acyl-[acyl-carrier-protein]–phospholipid O-acyltransferase	0.382	0.61	0.532	0.532
Acyl-[acyl-carrier-protein]–UDP-N-acetylglucosamine O-acyltransferase	0.382	0.61	0.532	0.532
Adenine phosphoribosyltransferase	0.382	0.61	0.532	0.532
Adenosylhomocysteine nucleosidase	0.382	0.61	0.532	0.532
Adenylate kinase	0.382	0.61	0.532	0.532
Adenylosuccinate lyase	0.382	0.61	0.532	0.532
Adenylosuccinate synthase	0.382	0.61	0.532	0.532
ADP-glyceromanno-heptose 6-epimerase	0.382	0.61	0.532	0.532
Alanine–tRNA ligase	0.382	0.61	0.532	0.532
Alanine racemase	0.382	0.61	0.532	0.532
All-trans-octaprenyl-diphosphate synthase	0.382	0.61	0.532	0.532
Amidophosphoribosyltransferase	0.382	0.61	0.532	0.532
Aminoacyl-tRNA hydrolase	0.382	0.61	0.532	0.532
Aminodeoxyfutalosine nucleosidase	0.382	0.61	0.532	0.532
Aminodeoxyfutalosine synthase	0.382	0.61	0.532	0.532
Anthranilate phosphoribosyltransferase	0.382	0.61	0.532	0.532
Anthranilate synthase	0.382	0.61	0.532	0.532
Arabinose-5-phosphate isomerase	0.382	0.61	0.532	0.532
Arginine–tRNA ligase	0.382	0.61	0.532	0.532
Arginine decarboxylase	0.382	0.61	0.532	0.532
Argininosuccinate lyase	0.382	0.61	0.532	0.532
Argininosuccinate synthase	0.382	0.61	0.532	0.532
Aryl-sulfate sulfotransferase	0.382	0.61	0.532	0.532
Asparaginase	0.382	0.61	0.532	0.532
Asparagine synthase (glutamine-hydrolyzing)	0.382	0.61	0.532	0.532
Asparaginyl-tRNA synthase (glutamine-hydrolyzing)	0.382	0.61	0.532	0.532
Aspartate–tRNA ligase	0.382	0.61	0.532	0.532
Aspartate-semialdehyde dehydrogenase	0.382	0.61	0.532	0.532
Aspartate 1-decarboxylase	0.382	0.61	0.532	0.532
Aspartate ammonia-lyase	0.382	0.61	0.532	0.532
Aspartate carbamoyltransferase	0.382	0.61	0.532	0.532
Aspartate kinase	0.382	0.61	0.532	0.532
Aspartate racemase	0.382	0.61	0.532	0.532
Aspartate transaminase	0.382	0.61	0.532	0.532
Assimilatory sulfite reductase (NADPH)	0.382	0.61	0.532	0.532
ATP phosphoribosyltransferase	0.382	0.61	0.532	0.532
Beta-ketoacyl-[acyl-carrier-protein] synthase I	0.382	0.61	0.532	0.532
Beta-ketoacyl-[acyl-carrier-protein] synthase II	0.382	0.61	0.532	0.532
Beta-ketoacyl-[acyl-carrier-protein] synthase III	0.382	0.61	0.532	0.532
Beta-N-acetylhexosaminidase	0.382	0.61	0.532	0.532
Biotin–[acetyl-CoA-carboxylase] ligase	0.382	0.61	0.532	0.532
Biotin carboxylase	0.382	0.61	0.532	0.532
Biotin synthase	0.382	0.61	0.532	0.532
Branched-chain-amino-acid transaminase	0.382	0.61	0.532	0.532
C-terminal processing peptidase	0.382	0.61	0.532	0.532
Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	0.382	0.61	0.532	0.532
Carbonate dehydratase	0.382	0.61	0.532	0.532
Carboxynorspermidine decarboxylase	0.382	0.61	0.532	0.532
CCA tRNA nucleotidyltransferase	0.382	0.61	0.532	0.532
CDP-diacylglycerol–glycerol-3-phosphate 3-phosphatidyltransferase	0.382	0.61	0.532	0.532
CDP-diacylglycerol–serine O-phosphatidyltransferase	0.382	0.61	0.532	0.532
Chorismate dehydratase	0.382	0.61	0.532	0.532
Chorismate mutase	0.382	0.61	0.532	0.532
Chorismate synthase	0.382	0.61	0.532	0.532
Citrate (Si)-synthase	0.382	0.61	0.532	0.532
CMP-N,N’-diacetyllegionaminic acid synthase	0.382	0.61	0.532	0.532
Coproporphyrinogen dehydrogenase	0.382	0.61	0.532	0.532
Crossover junction endodeoxyribonuclease	0.382	0.61	0.532	0.532
CTP synthase (glutamine hydrolyzing)	0.382	0.61	0.532	0.532
Cu(+) exporting ATPase	0.382	0.61	0.532	0.532
Cyclic dehypoxanthinyl futalosine synthase	0.382	0.61	0.532	0.532
Cyclic pyranopterin phosphate synthase	0.382	0.61	0.532	0.532
Cystathionine beta-lyase	0.382	0.61	0.532	0.532
Cysteine–tRNA ligase	0.382	0.61	0.532	0.532
Cysteine desulfurase	0.382	0.61	0.532	0.532
Cysteine synthase	0.382	0.61	0.532	0.532
Cytochrome-c oxidase	0.382	0.61	0.532	0.532
Cytochrome-c peroxidase	0.382	0.61	0.532	0.532
D-alanine–D-alanine ligase	0.382	0.61	0.532	0.532
D-amino-acid transaminase	0.382	0.61	0.532	0.532
D-glycero-alpha-D-manno-heptose-1,7-bisphosphate 7-phosphatase	0.382	0.61	0.532	0.532
D-glycero-beta-D-manno-heptose-7-phosphate kinase	0.382	0.61	0.532	0.532
D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase	0.382	0.61	0.532	0.532
D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase	0.382	0.61	0.532	0.532
D-sedoheptulose 7-phosphate isomerase	0.382	0.61	0.532	0.532
dCTP deaminase	0.382	0.61	0.532	0.532
Demethylmenaquinone methyltransferase	0.382	0.61	0.532	0.532
Deoxyribonuclease IV	0.382	0.61	0.532	0.532
Dephospho-CoA kinase	0.382	0.61	0.532	0.532
Diacylglycerol kinase (ATP)	0.382	0.61	0.532	0.532
Diaminohydroxyphosphoribosylaminopyrimidine deaminase	0.382	0.61	0.532	0.532
Diaminopimelate decarboxylase	0.382	0.61	0.532	0.532
Diaminopimelate epimerase	0.382	0.61	0.532	0.532
Dihydrofolate synthase	0.382	0.61	0.532	0.532
Dihydroneopterin aldolase	0.382	0.61	0.532	0.532
Dihydroorotase	0.382	0.61	0.532	0.532
Dihydroorotate dehydrogenase (quinone)	0.382	0.61	0.532	0.532
Dihydropteroate synthase	0.382	0.61	0.532	0.532
Dihydroxy-acid dehydratase	0.382	0.61	0.532	0.532
Dimethylallyltranstransferase	0.382	0.61	0.532	0.532
Dipeptidase E	0.382	0.61	0.532	0.532
diphosphate specific)	0.382	0.61	0.532	0.532
DNA-(apurinic or apyrimidinic site) lyase	0.382	0.61	0.532	0.532
DNA-3-methyladenine glycosylase I	0.382	0.61	0.532	0.532
DNA-directed DNA polymerase	0.382	0.61	0.532	0.532
DNA-directed RNA polymerase	0.382	0.61	0.532	0.532
DNA (cytosine-5-)-methyltransferase	0.382	0.61	0.532	0.532
DNA helicase	0.382	0.61	0.532	0.532
DNA ligase (ATP or NAD(+))	0.382	0.61	0.532	0.532
DNA ligase (ATP)	0.382	0.61	0.532	0.532
DNA ligase (ATP, ADP or GTP)	0.382	0.61	0.532	0.532
DNA ligase (NAD(+))	0.382	0.61	0.532	0.532
DNA topoisomerase	0.382	0.61	0.532	0.532
DNA topoisomerase (ATP-hydrolyzing)	0.382	0.61	0.532	0.532
dTMP kinase	0.382	0.61	0.532	0.532
Endopeptidase Clp	0.382	0.61	0.532	0.532
Endopeptidase La	0.382	0.61	0.532	0.532
Enoyl-[acyl-carrier-protein] reductase (NADH)	0.382	0.61	0.532	0.532
Enoyl-[acyl-carrier-protein] reductase (NADPH, Si-specific)	0.382	0.61	0.532	0.532
Exodeoxyribonuclease III	0.382	0.61	0.532	0.532
Exodeoxyribonuclease V	0.382	0.61	0.532	0.532
Exodeoxyribonuclease VII	0.382	0.61	0.532	0.532
Exopolyphosphatase	0.382	0.61	0.532	0.532
FAD synthetase	0.382	0.61	0.532	0.532
Ferrochelatase	0.382	0.61	0.532	0.532
Feruloyl esterase	0.382	0.61	0.532	0.532
Formate–tetrahydrofolate ligase	0.382	0.61	0.532	0.532
Formate dehydrogenase	0.382	0.61	0.532	0.532
Formate dehydrogenase (NADP(+))	0.382	0.61	0.532	0.532
Fructose-bisphosphatase	0.382	0.61	0.532	0.532
Fructose-bisphosphate aldolase	0.382	0.61	0.532	0.532
Fumarate hydratase	0.382	0.61	0.532	0.532
Fumarate reductase (quinol)	0.382	0.61	0.532	0.532
GalNAc(5)-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase	0.382	0.61	0.532	0.532
Glucosamine-1-phosphate N-acetyltransferase	0.382	0.61	0.532	0.532
Glucose-6-phosphate isomerase	0.382	0.61	0.532	0.532
Glutamate–ammonia ligase	0.382	0.61	0.532	0.532
Glutamate–tRNA ligase	0.382	0.61	0.532	0.532
Glutamate-1-semialdehyde 2,1-aminomutase	0.382	0.61	0.532	0.532
Glutamate carboxypeptidase	0.382	0.61	0.532	0.532
Glutamate dehydrogenase (NAD(P)(+))	0.382	0.61	0.532	0.532
Glutamate dehydrogenase (NADP(+))	0.382	0.61	0.532	0.532
Glutamate racemase	0.382	0.61	0.532	0.532
Glutamine–fructose-6-phosphate transaminase (isomerizing)	0.382	0.61	0.532	0.532
Glutaminyl-tRNA synthase (glutamine-hydrolyzing)	0.382	0.61	0.532	0.532
Glutamyl-tRNA reductase	0.382	0.61	0.532	0.532
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	0.382	0.61	0.532	0.532
Glycerate 3-kinase	0.382	0.61	0.532	0.532
Glycerate dehydrogenase	0.382	0.61	0.532	0.532
Glycerol-3-phosphate 1-O-acyltransferase	0.382	0.61	0.532	0.532
Glycerol-3-phosphate dehydrogenase (NAD(P)(+))	0.382	0.61	0.532	0.532
Glycine–tRNA ligase	0.382	0.61	0.532	0.532
Glycine hydroxymethyltransferase	0.382	0.61	0.532	0.532
GMP synthase (glutamine-hydrolyzing)	0.382	0.61	0.532	0.532
GTP cyclohydrolase I	0.382	0.61	0.532	0.532
GTP cyclohydrolase II	0.382	0.61	0.532	0.532
GTP diphosphokinase	0.382	0.61	0.532	0.532
Guanosine-5’-triphosphate,3’-diphosphate diphosphatase	0.382	0.61	0.532	0.532
Guanylate kinase	0.382	0.61	0.532	0.532
H(+)-transporting two-sector ATPase	0.382	0.61	0.532	0.532
Histidine–tRNA ligase	0.382	0.61	0.532	0.532
Histidine kinase	0.382	0.61	0.532	0.532
Histidinol-phosphatase	0.382	0.61	0.532	0.532
Histidinol-phosphate transaminase	0.382	0.61	0.532	0.532
Histidinol dehydrogenase	0.382	0.61	0.532	0.532
Holo-[acyl-carrier-protein] synthase	0.382	0.61	0.532	0.532
Homoserine dehydrogenase	0.382	0.61	0.532	0.532
Homoserine kinase	0.382	0.61	0.532	0.532
Homoserine O-acetyltransferase	0.382	0.61	0.532	0.532
HslU–HslV peptidase	0.382	0.61	0.532	0.532
HycI peptidase	0.382	0.61	0.532	0.532
Hydrogen:quinone oxidoreductase	0.382	0.61	0.532	0.532
Hydroxylamine reductase	0.382	0.61	0.532	0.532
Hydroxymethylbilane synthase	0.382	0.61	0.532	0.532
Hydroxymethylpyrimidine kinase	0.382	0.61	0.532	0.532
Imidazoleglycerol-phosphate dehydratase	0.382	0.61	0.532	0.532
IMP cyclohydrolase	0.382	0.61	0.532	0.532
IMP dehydrogenase	0.382	0.61	0.532	0.532
Indole-3-glycerol-phosphate synthase	0.382	0.61	0.532	0.532
Inorganic diphosphatase	0.382	0.61	0.532	0.532
Iron-chelate-transporting ATPase	0.382	0.61	0.532	0.532
Isocitrate dehydrogenase (NADP(+))	0.382	0.61	0.532	0.532
Isoleucine–tRNA ligase	0.382	0.61	0.532	0.532
isomerase	0.382	0.61	0.532	0.532
Kdo(2)-lipid IV(A) lauroyltransferase	0.382	0.61	0.532	0.532
Ketol-acid reductoisomerase (NADP(+))	0.382	0.61	0.532	0.532
L-fuculose-phosphate aldolase	0.382	0.61	0.532	0.532
L-seryl-tRNA(Sec) selenium transferase	0.382	0.61	0.532	0.532
L(+)-tartrate dehydratase	0.382	0.61	0.532	0.532
Leucine–tRNA ligase	0.382	0.61	0.532	0.532
Leucyl aminopeptidase	0.382	0.61	0.532	0.532
Lipid-A-disaccharide synthase	0.382	0.61	0.532	0.532
Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase	0.382	0.61	0.532	0.532
Long-chain-fatty-acid–[acyl-carrier-protein] ligase	0.382	0.61	0.532	0.532
Long-chain-fatty-acid–CoA ligase	0.382	0.61	0.532	0.532
Lysine–tRNA ligase	0.382	0.61	0.532	0.532
Malate dehydrogenase	0.382	0.61	0.532	0.532
Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))	0.382	0.61	0.532	0.532
Malate dehydrogenase (quinone)	0.382	0.61	0.532	0.532
Methenyltetrahydrofolate cyclohydrolase	0.382	0.61	0.532	0.532
Methionine–tRNA ligase	0.382	0.61	0.532	0.532
Methionine adenosyltransferase	0.382	0.61	0.532	0.532
Methionyl-tRNA formyltransferase	0.382	0.61	0.532	0.532
Methionyl aminopeptidase	0.382	0.61	0.532	0.532
Methylated-DNA–[protein]-cysteine S-methyltransferase	0.382	0.61	0.532	0.532
Methylenetetrahydrofolate dehydrogenase (NADP(+))	0.382	0.61	0.532	0.532
Molybdate-transporting ATPase	0.382	0.61	0.532	0.532
Molybdenum cofactor guanylyltransferase	0.382	0.61	0.532	0.532
Molybdopterin adenylyltransferase	0.382	0.61	0.532	0.532
Molybdopterin molybdotransferase	0.382	0.61	0.532	0.532
Molybdopterin synthase	0.382	0.61	0.532	0.532
N-acetylmuramoyl-L-alanine amidase	0.382	0.61	0.532	0.532
N-acylneuraminate cytidylyltransferase	0.382	0.61	0.532	0.532
N-carbamoyl-L-amino-acid hydrolase	0.382	0.61	0.532	0.532
N-carbamoylputrescine amidase	0.382	0.61	0.532	0.532
N(6)-L-threonylcarbamoyladenine synthase	0.382	0.61	0.532	0.532
N,N’-diacetyllegionaminate synthase	0.382	0.61	0.532	0.532
NAD(+) kinase	0.382	0.61	0.532	0.532
NAD(+) synthase	0.382	0.61	0.532	0.532
NADH:ubiquinone reductase (H(+)-translocating)	0.382	0.61	0.532	0.532
NADPH dehydrogenase	0.382	0.61	0.532	0.532
Nicotinamide-nucleotide amidase	0.382	0.61	0.532	0.532
Nicotinate-nucleotide adenylyltransferase	0.382	0.61	0.532	0.532
Nicotinate phosphoribosyltransferase	0.382	0.61	0.532	0.532
Nitrate reductase	0.382	0.61	0.532	0.532
Nitric-oxide reductase (cytochrome c)	0.382	0.61	0.532	0.532
Nitrilase	0.382	0.61	0.532	0.532
Nitronate monooxygenase	0.382	0.61	0.532	0.532
Nitrous-oxide reductase	0.382	0.61	0.532	0.532
Nucleoside-diphosphate kinase	0.382	0.61	0.532	0.532
O-acetylhomoserine aminocarboxypropyltransferase	0.382	0.61	0.532	0.532
Ornithine carbamoyltransferase	0.382	0.61	0.532	0.532
Orotate phosphoribosyltransferase	0.382	0.61	0.532	0.532
Orotidine-5’-phosphate decarboxylase	0.382	0.61	0.532	0.532
Pantetheine-phosphate adenylyltransferase	0.382	0.61	0.532	0.532
Pantoate–beta-alanine ligase (AMP-forming)	0.382	0.61	0.532	0.532
Pantothenate kinase	0.382	0.61	0.532	0.532
Pectate lyase	0.382	0.61	0.532	0.532
Peptidase Do	0.382	0.61	0.532	0.532
Peptide-methionine (R)-S-oxide reductase	0.382	0.61	0.532	0.532
Peptide-methionine (S)-S-oxide reductase	0.382	0.61	0.532	0.532
Peptide chain release factor N(5)-glutamine methyltransferase	0.382	0.61	0.532	0.532
Peptide deformylase	0.382	0.61	0.532	0.532
Peptidylprolyl isomerase	0.382	0.61	0.532	0.532
Peroxiredoxin	0.382	0.61	0.532	0.532
Phenylalanine–tRNA ligase	0.382	0.61	0.532	0.532
Phosphate acetyltransferase	0.382	0.61	0.532	0.532
Phosphatidate cytidylyltransferase	0.382	0.61	0.532	0.532
Phosphatidylglycerophosphatase	0.382	0.61	0.532	0.532
Phosphatidylserine decarboxylase	0.382	0.61	0.532	0.532
Phosphinothricin acetyltransferase	0.382	0.61	0.532	0.532
Phospho-N-acetylmuramoyl-pentapeptide-transferase	0.382	0.61	0.532	0.532
Phosphoenolpyruvate carboxykinase (ATP)	0.382	0.61	0.532	0.532
Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)	0.382	0.61	0.532	0.532
Phosphoglucosamine mutase	0.382	0.61	0.532	0.532
Phosphoglycerate dehydrogenase	0.382	0.61	0.532	0.532
Phosphoglycerate kinase	0.382	0.61	0.532	0.532
Phosphoglycerate mutase (2,3-diphosphoglycerate-independent)	0.382	0.61	0.532	0.532
Phosphoglycolate phosphatase	0.382	0.61	0.532	0.532
Phospholipase A(1)	0.382	0.61	0.532	0.532
Phospholipase A(2)	0.382	0.61	0.532	0.532
Phosphomannomutase	0.382	0.61	0.532	0.532
Phosphomethylpyrimidine kinase	0.382	0.61	0.532	0.532
Phosphomethylpyrimidine synthase	0.382	0.61	0.532	0.532
Phosphopantothenate–cysteine ligase	0.382	0.61	0.532	0.532
Phosphopantothenoylcysteine decarboxylase	0.382	0.61	0.532	0.532
Phosphopyruvate hydratase	0.382	0.61	0.532	0.532
Phosphoribosyl-AMP cyclohydrolase	0.382	0.61	0.532	0.532
Phosphoribosyl-ATP diphosphatase	0.382	0.61	0.532	0.532
Phosphoribosylamine–glycine ligase	0.382	0.61	0.532	0.532
Phosphoribosylaminoimidazolecarboxamide formyltransferase	0.382	0.61	0.532	0.532
Phosphoribosylaminoimidazolesuccinocarboxamide synthase	0.382	0.61	0.532	0.532
Phosphoribosylanthranilate isomerase	0.382	0.61	0.532	0.532
Phosphoribosylformylglycinamidine cyclo-ligase	0.382	0.61	0.532	0.532
Phosphoribosylformylglycinamidine synthase	0.382	0.61	0.532	0.532
Phosphoribosylglycinamide formyltransferase	0.382	0.61	0.532	0.532
Phosphoserine phosphatase	0.382	0.61	0.532	0.532
Phosphoserine transaminase	0.382	0.61	0.532	0.532
Polar-amino-acid-transporting ATPase	0.382	0.61	0.532	0.532
Polyphosphate kinase	0.382	0.61	0.532	0.532
Polyribonucleotide nucleotidyltransferase	0.382	0.61	0.532	0.532
Porphobilinogen synthase	0.382	0.61	0.532	0.532
Prephenate dehydratase	0.382	0.61	0.532	0.532
Prephenate dehydrogenase	0.382	0.61	0.532	0.532
Prepilin peptidase	0.382	0.61	0.532	0.532
PreQ(1) synthase	0.382	0.61	0.532	0.532
Proline–tRNA ligase	0.382	0.61	0.532	0.532
Protein-disulfide reductase	0.382	0.61	0.532	0.532
Protein-glutamate methylesterase	0.382	0.61	0.532	0.532
Protein-glutamate O-methyltransferase	0.382	0.61	0.532	0.532
Protein-L-isoaspartate(D-aspartate) O-methyltransferase	0.382	0.61	0.532	0.532
Protein-serine/threonine phosphatase	0.382	0.61	0.532	0.532
Protein disulfide-isomerase	0.382	0.61	0.532	0.532
Pseudaminic acid cytidylyltransferase	0.382	0.61	0.532	0.532
Pseudaminic acid synthase	0.382	0.61	0.532	0.532
Pyridoxal kinase	0.382	0.61	0.532	0.532
Pyruvate carboxylase	0.382	0.61	0.532	0.532
Pyruvate kinase	0.382	0.61	0.532	0.532
Pyruvate synthase	0.382	0.61	0.532	0.532
Quinol–cytochrome-c reductase	0.382	0.61	0.532	0.532
Riboflavin kinase	0.382	0.61	0.532	0.532
Riboflavin synthase	0.382	0.61	0.532	0.532
Ribonuclease H	0.382	0.61	0.532	0.532
Ribonuclease III	0.382	0.61	0.532	0.532
Ribonucleoside-diphosphate reductase	0.382	0.61	0.532	0.532
Ribonucleoside-triphosphate reductase	0.382	0.61	0.532	0.532
Ribose-5-phosphate isomerase	0.382	0.61	0.532	0.532
Ribose-phosphate diphosphokinase	0.382	0.61	0.532	0.532
Ribulose-phosphate 3-epimerase	0.382	0.61	0.532	0.532
S-adenosylmethionine:tRNA ribosyltransferase-isomerase	0.382	0.61	0.532	0.532
S-ribosylhomocysteine lyase	0.382	0.61	0.532	0.532
Saccharopine dehydrogenase (NAD(+), L-lysine-forming)	0.382	0.61	0.532	0.532
Selenide, water dikinase	0.382	0.61	0.532	0.532
Serine–tRNA ligase	0.382	0.61	0.532	0.532
Serine O-acetyltransferase	0.382	0.61	0.532	0.532
Shikimate dehydrogenase	0.382	0.61	0.532	0.532
Shikimate kinase	0.382	0.61	0.532	0.532
Signal peptidase I	0.382	0.61	0.532	0.532
Signal peptidase II	0.382	0.61	0.532	0.532
Site-specific DNA-methyltransferase (adenine-specific)	0.382	0.61	0.532	0.532
Ste24 endopeptidase	0.382	0.61	0.532	0.532
Succinate dehydrogenase (quinone)	0.382	0.61	0.532	0.532
Succinyl-diaminopimelate desuccinylase	0.382	0.61	0.532	0.532
Sulfate adenylyltransferase	0.382	0.61	0.532	0.532
Sulfur carrier protein ThiS adenylyltransferase	0.382	0.61	0.532	0.532
Superoxide dismutase	0.382	0.61	0.532	0.532
Tetraacyldisaccharide 4’-kinase	0.382	0.61	0.532	0.532
Tetrahydrofolate synthase	0.382	0.61	0.532	0.532
Thiamine-phosphate diphosphorylase	0.382	0.61	0.532	0.532
Thiamine-phosphate kinase	0.382	0.61	0.532	0.532
Thiazole synthase	0.382	0.61	0.532	0.532
Thioredoxin-disulfide reductase	0.382	0.61	0.532	0.532
Threonine–tRNA ligase	0.382	0.61	0.532	0.532
Threonine ammonia-lyase	0.382	0.61	0.532	0.532
Threonine synthase	0.382	0.61	0.532	0.532
Thymidylate synthase (FAD)	0.382	0.61	0.532	0.532
Transaldolase	0.382	0.61	0.532	0.532
transferase	0.382	0.61	0.532	0.532
Transketolase	0.382	0.61	0.532	0.532
Trimethylamine-N-oxide reductase (cytochrome c)	0.382	0.61	0.532	0.532
Triose-phosphate isomerase	0.382	0.61	0.532	0.532
Tripeptide aminopeptidase	0.382	0.61	0.532	0.532
tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase	0.382	0.61	0.532	0.532
tRNA-guanine(34) transglycosylase	0.382	0.61	0.532	0.532
tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase	0.382	0.61	0.532	0.532
tRNA (cytidine(34)-2’-O)-methyltransferase	0.382	0.61	0.532	0.532
tRNA (guanine(37)-N(1))-methyltransferase	0.382	0.61	0.532	0.532
tRNA (guanine(46)-N(7))-methyltransferase	0.382	0.61	0.532	0.532
tRNA (uracil(54)-C(5))-methyltransferase	0.382	0.61	0.532	0.532
tRNA dimethylallyltransferase	0.382	0.61	0.532	0.532
tRNA pseudouridine(13) synthase	0.382	0.61	0.532	0.532
tRNA pseudouridine(38-40) synthase	0.382	0.61	0.532	0.532
tRNA pseudouridine(55) synthase	0.382	0.61	0.532	0.532
tRNA(Ile)-lysidine synthetase	0.382	0.61	0.532	0.532
Tryptophan–tRNA ligase	0.382	0.61	0.532	0.532
Tryptophan synthase	0.382	0.61	0.532	0.532
Tungstate-importing ATPase	0.382	0.61	0.532	0.532
Type I site-specific deoxyribonuclease	0.382	0.61	0.532	0.532
Tyrosine–tRNA ligase	0.382	0.61	0.532	0.532
UDP-2,3-diacylglucosamine diphosphatase	0.382	0.61	0.532	0.532
UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase	0.382	0.61	0.532	0.532
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	0.382	0.61	0.532	0.532
UDP-3-O-acyl-N-acetylglucosamine deacetylase	0.382	0.61	0.532	0.532
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase	0.382	0.61	0.532	0.532
UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase	0.382	0.61	0.532	0.532
UDP-glucose 4-epimerase	0.382	0.61	0.532	0.532
UDP-glucose 6-dehydrogenase	0.382	0.61	0.532	0.532
UDP-glucuronate 4-epimerase	0.382	0.61	0.532	0.532
UDP-N-acetylbacillosamine N-acetyltransferase	0.382	0.61	0.532	0.532
UDP-N-acetylbacillosamine transaminase	0.382	0.61	0.532	0.532
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0.382	0.61	0.532	0.532
UDP-N-acetylglucosamine 4,6-dehydratase (configuration-retaining)	0.382	0.61	0.532	0.532
UDP-N-acetylglucosamine 4,6-dehydratase (inverting)	0.382	0.61	0.532	0.532
UDP-N-acetylglucosamine diphosphorylase	0.382	0.61	0.532	0.532
UDP-N-acetylmuramate–L-alanine ligase	0.382	0.61	0.532	0.532
UDP-N-acetylmuramate dehydrogenase	0.382	0.61	0.532	0.532
UDP-N-acetylmuramoyl-L-alanine–D-glutamate ligase	0.382	0.61	0.532	0.532
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase	0.382	0.61	0.532	0.532
UDP-N-acetylmuramoyl-tripeptide–D-alanyl-D-alanine ligase	0.382	0.61	0.532	0.532
UDP-N,N’-diacetylbacillosamine 2-epimerase (hydrolyzing)	0.382	0.61	0.532	0.532
UDP-sugar diphosphatase	0.382	0.61	0.532	0.532
UMP kinase	0.382	0.61	0.532	0.532
Undecaprenyl-diphosphate phosphatase	0.382	0.61	0.532	0.532
Undecaprenyl-diphosphooligosaccharide–protein glycotransferase	0.382	0.61	0.532	0.532
Uracil-DNA glycosylase	0.382	0.61	0.532	0.532
Uracil phosphoribosyltransferase	0.382	0.61	0.532	0.532
Uroporphyrinogen-III synthase	0.382	0.61	0.532	0.532
Uroporphyrinogen decarboxylase	0.382	0.61	0.532	0.532
UTP–glucose-1-phosphate uridylyltransferase	0.382	0.61	0.532	0.532
Valine–tRNA ligase	0.382	0.61	0.532	0.532
Xaa-Pro aminopeptidase	0.382	0.61	0.532	0.532
Xanthine phosphoribosyltransferase	0.382	0.61	0.532	0.532
XTP/dITP diphosphatase	0.382	0.61	0.532	0.532

# merge with tb.ra for full results table
full.res <- left_join(tb.ra, results.out, by = "description")

write.csv(full.res, "output/picrust_ec_stratefied_campy_data_results.csv", row.names = F)

Part 2 KO Data

descriptions <- readr::read_tsv("data/PICRUST/ko_pred_metagenome_unstrat_descrip.tsv")[,1:2] %>%
  distinct()

-- Column specification --------------------------------------------------------
cols(
  .default = col_double(),
  `function` = col_character(),
  description = col_character()
)
i Use `spec()` for the full column specifications.

colnames(descriptions) <- c("func", "description")

pi.dat <- readxl::read_xlsx("data/PICRUST-Stratified/KO_campy.xlsx")
colnames(pi.dat) <- c("func",  colnames(pi.dat)[-c(1)])

# add descriptions to dataframe
pi.dat <- left_join(pi.dat, descriptions, by="func")
pi.dat <- pi.dat[,c(1,161,3:160)]

# aggregate descriptions to get 1 description per row - unique;y defined.
pi.dat <- pi.dat %>%
  group_by(description) %>%
  summarise(across(`X1.S37.Jun172016`:`X99.D01.S37.Jun232016`,.fns = mean))

# make long format
pi.dat <- pi.dat %>%
  pivot_longer(
    cols=`X1.S37.Jun172016`:`X99.D01.S37.Jun232016`,
    names_to = "ID",
    values_to = "Abundance"
  ) %>%
  mutate(
    ID = substr(ID, 2, 99)
  )

d <- as.data.frame(dat.16s)
mydata <- full_join(pi.dat, d)

Joining, by = "ID"

Warning in class(x) <- c(setdiff(subclass, tibble_class), tibble_class): Setting
class(x) to multiple strings ("tbl_df", "tbl", ...); result will no longer be an
S4 object

mydata <- mydata %>%
  mutate(
    ID.n = as.numeric(as.factor(ID)),
    description.n = as.numeric(as.factor(description))
  ) %>%
  group_by(description)%>%
  mutate(avgA = mean(Abundance))

Abundance

# Run on all descriptions
tb.ra1 <- mydata %>%
  group_by(description) %>%
  summarise(ng = n(),
            Overall.M = mean(Abundance),
            Overall.SE = sd(Abundance)/sqrt(ng))
tb.ra2m <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(M = mean(Abundance)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = M)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2se <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n(),SE = sd(Abundance)/sqrt(ng)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = SE)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2var <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n(), VAR = var(Abundance)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = VAR)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2ng <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n()) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = ng)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra <- left_join(tb.ra1, tb.ra2m)

Joining, by = "description"

tb.ra <- cbind(tb.ra, tb.ra2se[,-1])
tb.ra <- cbind(tb.ra, tb.ra2var[,-1])
tb.ra <- cbind(tb.ra, tb.ra2ng[,-1]) 

colnames(tb.ra) <- c("description", "ng", "Overall Mean", "Overall SE", "Non-Tumor Mean", "Tumor Mean", "Non-Tumor SE", "Tumor SE","Non-Tumor Var", "Tumor Var", "Non-Tumor Ng", "Tumor Ng")
tb.ra <- tb.ra %>%
  arrange(desc(`Overall Mean`))
tb.ra <- tb.ra[, c("description", "Overall Mean", "Overall SE","Tumor Mean","Tumor Var", "Tumor SE","Tumor Ng", "Non-Tumor Mean","Non-Tumor Var", "Non-Tumor SE", "Non-Tumor Ng")]

# compute t-test
tb.ra <- tb.ra %>%
  mutate(
    SEpooled = sqrt(`Tumor Var`/`Tumor Ng` + `Non-Tumor Var`/`Non-Tumor Ng`),
    t = (`Tumor Mean` - `Non-Tumor Mean`)/(SEpooled),
    df = ((`Tumor Var`/`Tumor Ng` + `Non-Tumor Var`/`Non-Tumor Ng`)**2)/(((`Tumor Var`/`Tumor Ng`)**2)/(`Tumor Ng`-1) + ((`Non-Tumor Var`/`Non-Tumor Ng`)**2)/(`Non-Tumor Ng`-1)),
    p = pt(q = abs(t), df=df, lower.tail = F)*2,
    fdr_p = p.adjust(p, method="fdr")
  )



kable(tb.ra, format="html", digits=5, caption="Stratefied KO Data - Campylobacter concisus: Average Abundance of Each Description (sorted in descending order)") %>%
  kable_styling(full_width = T) %>%
  scroll_box(width = "100%", height="600px")

Stratefied KO Data - Campylobacter concisus: Average Abundance of Each Description (sorted in descending order)

description	Overall Mean	Overall SE	Tumor Mean	Tumor Var	Tumor SE	Tumor Ng	Non-Tumor Mean	Non-Tumor Var	Non-Tumor SE	Non-Tumor Ng	SEpooled	t	df	p	fdr_p
mcp; methyl-accepting chemotaxis protein	5.25316	1.56480	6.46154	370.096	2.38617	65	4.40860	401.005	2.07651	93	3.16317	0.64901	141.28	0.51738	0.51738
K07126; uncharacterized protein	4.72785	1.40832	5.81538	299.778	2.14755	65	3.96774	324.814	1.86886	93	2.84686	0.64901	141.28	0.51738	0.51738
fdoG, fdhF, fdwA; formate dehydrogenase major subunit [EC:1.17.1.9]	4.20253	1.25184	5.16923	236.862	1.90893	65	3.52688	256.643	1.66121	93	2.53054	0.64901	141.28	0.51738	0.51738
TC.NSS; neurotransmitter:Na+ symporter, NSS family	2.62658	0.78240	3.23077	92.524	1.19308	65	2.20430	100.251	1.03825	93	1.58159	0.64901	141.28	0.51738	0.51738
K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]	2.10127	0.62592	2.58462	59.215	0.95447	65	1.76344	64.161	0.83060	93	1.26527	0.64901	141.28	0.51738	0.51738
torZ; trimethylamine-N-oxide reductase (cytochrome c) [EC:1.7.2.3]	2.10127	0.62592	2.58462	59.215	0.95447	65	1.76344	64.161	0.83060	93	1.26527	0.64901	141.28	0.51738	0.51738
ABC.CD.A; putative ABC transport system ATP-binding protein	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
ABC.CD.P; putative ABC transport system permease protein	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
ABC.PA.P; polar amino acid transport system permease protein	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
ABC.PA.S; polar amino acid transport system substrate-binding protein	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
acpP; acyl carrier protein	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
dnaC; DNA replication protein DnaC	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
E3.5.1.1, ansA, ansB; L-asparaginase [EC:3.5.1.1]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
fur, zur, furB; Fur family transcriptional regulator, ferric uptake regulator	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
K02483; two-component system, OmpR family, response regulator	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
modA; molybdate transport system substrate-binding protein	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
thrC; threonine synthase [EC:4.2.3.1]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]	1.57595	0.46944	1.93846	33.309	0.71585	65	1.32258	36.090	0.62295	93	0.94895	0.64901	141.28	0.51738	0.51738
ABC.FEV.A; iron complex transport system ATP-binding protein [EC:3.6.3.34]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
ABC.FEV.P; iron complex transport system permease protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
ABC.FEV.S; iron complex transport system substrate-binding protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:3.6.3.21]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
assT; arylsulfate sulfotransferase [EC:2.8.2.22]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
ATPF0B, atpF; F-type H+-transporting ATPase subunit b	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
bcr, tcaB; MFS transporter, DHA1 family, multidrug resistance protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
bdhAB; butanol dehydrogenase [EC:1.1.1.-]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
comEA; competence protein ComEA	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
copA, ATP7; Cu+-exporting ATPase [EC:3.6.3.54]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
dnaJ; molecular chaperone DnaJ	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
dsbA; thiol:disulfide interchange protein DsbA	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
exbD; biopolymer transport protein ExbD	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
fdoH, fdsB; formate dehydrogenase iron-sulfur subunit	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
flgE; flagellar hook protein FlgE	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
flgG; flagellar basal-body rod protein FlgG	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
fliC; flagellin	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
fliNY, fliN; flagellar motor switch protein FliN/FliY	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
fliY; cystine transport system substrate-binding protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
gph; phosphoglycolate phosphatase [EC:3.1.3.18]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
gspG; general secretion pathway protein G	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.99.1.1 4.99.1.9]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
hemN, hemZ; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
iadA; beta-aspartyl-dipeptidase (metallo-type) [EC:3.4.19.-]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
K06882; uncharacterized protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
K07043; uncharacterized protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
K07090; uncharacterized protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
K07133; uncharacterized protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
K07318; adenine-specific DNA-methyltransferase [EC:2.1.1.72]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
K09943; uncharacterized protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
lemA; LemA protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
leuA, IMS; 2-isopropylmalate synthase [EC:2.3.3.13]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
metQ; D-methionine transport system substrate-binding protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
mnmA, trmU; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
modB; molybdate transport system permease protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
modE; molybdate transport system regulatory protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
moeA; molybdopterin molybdotransferase [EC:2.10.1.1]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
motB; chemotaxis protein MotB	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
mreB; rod shape-determining protein MreB and related proteins	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
napG; ferredoxin-type protein NapG	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
napH; ferredoxin-type protein NapH	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
pel; pectate lyase [EC:4.2.2.2]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
pepE; dipeptidase E [EC:3.4.13.21]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
pglB; undecaprenyl-diphosphooligosaccharide—protein glycotransferase [EC:2.4.99.19]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
pglH; GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase [EC:2.4.1.292]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
pilT; twitching motility protein PilT	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
ppx-gppA; exopolyphosphatase / guanosine-5’-triphosphate,3’-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
praC, xylH; 4-oxalocrotonate tautomerase [EC:5.3.2.6]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
psd, PISD; phosphatidylserine decarboxylase [EC:4.1.1.65]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
rarD; chloramphenicol-sensitive protein RarD	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
TC.AGCS; alanine or glycine:cation symporter, AGCS family	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
TC.FEV.OM2, cirA, cfrA, hmuR; outer membrane receptor for ferrienterochelin and colicins	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
TC.FEV.OM3, tbpA, hemR, lbpA, hpuB, bhuR, hugA, hmbR; hemoglobin/transferrin/lactoferrin receptor protein	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
tonB; periplasmic protein TonB	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
torC; trimethylamine-N-oxide reductase (cytochrome c), cytochrome c-type subunit TorC	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
uvrD, pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]	1.05063	0.31296	1.29231	14.804	0.47723	65	0.88172	16.040	0.41530	93	0.63263	0.64901	141.28	0.51738	0.51738
AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid–[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ABC-2.A; ABC-2 type transport system ATP-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ABC-2.P; ABC-2 type transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ABC.CYST.A; cystine transport system ATP-binding protein [EC:3.6.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ABC.CYST.P; cystine transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ABC.PE.A1; peptide/nickel transport system ATP-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ABC.PE.P; peptide/nickel transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ABC.PE.P1; peptide/nickel transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ABC.PE.S; peptide/nickel transport system substrate-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
abgA; aminobenzoyl-glutamate utilization protein A	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ackA; acetate kinase [EC:2.7.2.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
acrB, mexB, adeJ, smeE, mtrD, cmeB; multidrug efflux pump	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
adk, AK; adenylate kinase [EC:2.7.4.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
alaC; alanine-synthesizing transaminase [EC:2.6.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
alr; alanine racemase [EC:5.1.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
APRT, apt; adenine phosphoribosyltransferase [EC:2.4.2.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aqpZ; aquaporin Z	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
argH, ASL; argininosuccinate lyase [EC:4.3.2.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aroB; 3-dehydroquinate synthase [EC:4.2.3.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aroC; chorismate synthase [EC:4.2.3.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aroE; shikimate dehydrogenase [EC:1.1.1.25]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aroQ, qutE; 3-dehydroquinate dehydratase II [EC:4.2.1.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
asnB, ASNS; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aspA; aspartate ammonia-lyase [EC:4.3.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aspB; aspartate aminotransferase [EC:2.6.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ATPF0A, atpB; F-type H+-transporting ATPase subunit a	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ATPF0C, atpE; F-type H+-transporting ATPase subunit c	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ATPF1A, atpA; F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ATPF1B, atpD; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ATPF1D, atpH; F-type H+-transporting ATPase subunit delta	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ATPF1E, atpC; F-type H+-transporting ATPase subunit epsilon	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ATPF1G, atpG; F-type H+-transporting ATPase subunit gamma	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
bamD; outer membrane protein assembly factor BamD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
BCP, PRXQ, DOT5; peroxiredoxin Q/BCP [EC:1.11.1.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
betT, betS; choline/glycine/proline betaine transport protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
bioB; biotin synthase [EC:2.8.1.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
birA; BirA family transcriptional regulator, biotin operon repressor / biotin—[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
carA, CPA1; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CARP, pepA; leucyl aminopeptidase [EC:3.4.11.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cas1; CRISP-associated protein Cas1	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cas2; CRISPR-associated protein Cas2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 3.6.4.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cas5h; CRISPR-associated protein Cas5h	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cbpA; curved DNA-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ccoN; cytochrome c oxidase cbb3-type subunit I [EC:1.9.3.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ccoO; cytochrome c oxidase cbb3-type subunit II	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ccoP; cytochrome c oxidase cbb3-type subunit III	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ccoQ; cytochrome c oxidase cbb3-type subunit IV	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cheV; two-component system, chemotaxis family, chemotaxis protein CheV	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cheW; purine-binding chemotaxis protein CheW	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cheY; two-component system, chemotaxis family, chemotaxis protein CheY	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CHO1, pssA; CDP-diacylglycerol—serine O-phosphatidyltransferase [EC:2.7.8.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
clpB; ATP-dependent Clp protease ATP-binding subunit ClpB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
clpX, CLPX; ATP-dependent Clp protease ATP-binding subunit ClpX	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cmeR; TetR/AcrR family transcriptional regulator, cmeABC operon repressor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
coaBC, dfp; phosphopantothenoylcysteine decarboxylase / phosphopantothenate—cysteine ligase [EC:4.1.1.36 6.3.2.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
coaE; dephospho-CoA kinase [EC:2.7.1.24]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
coaX; type III pantothenate kinase [EC:2.7.1.33]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
comEC; competence protein ComEC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
comFC; competence protein ComFC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
comM; magnesium chelatase family protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
corA; magnesium transporter	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cpg; glutamate carboxypeptidase [EC:3.4.17.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
crcB, FEX; fluoride exporter	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CS, gltA; citrate synthase [EC:2.3.3.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
csh1; CRISPR-associated protein Csh1	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
csh2; CRISPR-associated protein Csh2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
csrA; carbon storage regulator	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cutA; periplasmic divalent cation tolerance protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cutF, nlpE; copper homeostasis protein (lipoprotein)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cvpA; membrane protein required for colicin V production	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CYC; cytochrome c	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cydA; cytochrome bd ubiquinol oxidase subunit I [EC:1.10.3.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cydB; cytochrome bd ubiquinol oxidase subunit II [EC:1.10.3.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cynT, can; carbonic anhydrase [EC:4.2.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cysE; serine O-acetyltransferase [EC:2.3.1.30]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cysK; cysteine synthase A [EC:2.5.1.47]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
cysQ, MET22, BPNT1; 3’(2’), 5’-bisphosphate nucleotidase [EC:3.1.3.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
czcD, zitB; cobalt-zinc-cadmium efflux system protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dadA; D-amino-acid dehydrogenase [EC:1.4.5.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dapF; diaminopimelate epimerase [EC:5.1.1.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dat; D-alanine transaminase [EC:2.6.1.21]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dcd; dCTP deaminase [EC:3.5.4.13]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dctA; aerobic C4-dicarboxylate transport protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dctM; C4-dicarboxylate transporter, DctM subunit	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dctP; C4-dicarboxylate-binding protein DctP	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dctQ; C4-dicarboxylate transporter, DctQ subunit	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dcuA; anaerobic C4-dicarboxylate transporter DcuA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dcuB; anaerobic C4-dicarboxylate transporter DcuB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dedD; DedD protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
degP, htrA; serine protease Do [EC:3.4.21.107]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DHODH, pyrD; dihydroorotate dehydrogenase [EC:1.3.5.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dinJ; DNA-damage-inducible protein J	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
djlA; DnaJ like chaperone protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dksA; DnaK suppressor protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dnaA; chromosomal replication initiator protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dnaB; replicative DNA helicase [EC:3.6.4.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dnaG; DNA primase [EC:2.7.7.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dnaK, HSPA9; molecular chaperone DnaK	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dps; starvation-inducible DNA-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dsbB; disulfide bond formation protein DsbB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dsbD; thiol:disulfide interchange protein DsbD [EC:1.8.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E1.1.1.3; homoserine dehydrogenase [EC:1.1.1.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E1.1.1.40, maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E1.6.99.1; NADPH2 dehydrogenase [EC:1.6.99.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.1.1.77, pcm; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.2.1.2, talA, talB; transaldolase [EC:2.2.1.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.7.1.71, aroK, aroL; shikimate kinase [EC:2.7.1.71]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.7.4.8, gmk; guanylate kinase [EC:2.7.4.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.7.7.3A, coaD, kdtB; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E2.7.7.41, CDS1, CDS2, cdsA; phosphatidate cytidylyltransferase [EC:2.7.7.41]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E3.1.11.2, xthA; exodeoxyribonuclease III [EC:3.1.11.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E3.4.21.102, prc, ctpA; carboxyl-terminal processing protease [EC:3.4.21.102]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E3.5.5.1; nitrilase [EC:3.5.5.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E3.5.99.7; 1-aminocyclopropane-1-carboxylate deaminase [EC:3.5.99.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E4.1.1.49, pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E4.3.1.19, ilvA, tdcB; threonine dehydratase [EC:4.3.1.19]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E5.1.3.6; UDP-glucuronate 4-epimerase [EC:5.1.3.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
eco; ecotin	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
efp; elongation factor P	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
engA, der; GTPase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
engB; GTP-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ENO, eno; enolase [EC:4.2.1.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
eptA, pmrC; lipid A ethanolaminephosphotransferase [EC:2.7.8.43]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
era, ERAL1; GTPase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
exbB; biopolymer transport protein ExbB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fadL; long-chain fatty acid transport protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
FAEB; feruloyl esterase [EC:3.1.1.73]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fdhA; formate dehydrogenase (NADP+) alpha subunit [EC:1.17.1.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fdhD; FdhD protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fdoI, fdsG; formate dehydrogenase subunit gamma	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fhaB; filamentous hemagglutinin	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fhs; formate–tetrahydrofolate ligase [EC:6.3.4.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flaG; flagellar protein FlaG	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fldA, nifF, isiB; flavodoxin I	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flgA; flagella basal body P-ring formation protein FlgA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flgB; flagellar basal-body rod protein FlgB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flgC; flagellar basal-body rod protein FlgC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flgD; flagellar basal-body rod modification protein FlgD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flgH; flagellar L-ring protein precursor FlgH	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flgI; flagellar P-ring protein precursor FlgI	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flgK; flagellar hook-associated protein 1 FlgK	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flgL; flagellar hook-associated protein 3 FlgL	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flhA; flagellar biosynthesis protein FlhA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flhB; flagellar biosynthetic protein FlhB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flhB2; flagellar biosynthesis protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flhF; flagellar biosynthesis protein FlhF	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
flhG, fleN; flagellar biosynthesis protein FlhG	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliA; RNA polymerase sigma factor for flagellar operon FliA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliD; flagellar hook-associated protein 2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliE; flagellar hook-basal body complex protein FliE	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliF; flagellar M-ring protein FliF	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliG; flagellar motor switch protein FliG	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliH; flagellar assembly protein FliH	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliI; flagellum-specific ATP synthase [EC:3.6.3.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliL; flagellar FliL protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliM; flagellar motor switch protein FliM	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliP; flagellar biosynthetic protein FliP	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliQ; flagellar biosynthetic protein FliQ	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliR; flagellar biosynthetic protein FliR	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliS; flagellar protein FliS	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fliW; flagellar assembly factor FliW	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
folP; dihydropteroate synthase [EC:2.5.1.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
frdA; fumarate reductase flavoprotein subunit [EC:1.3.5.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
frdB; fumarate reductase iron-sulfur subunit [EC:1.3.5.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
frdC; fumarate reductase subunit C	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
frr, MRRF, RRF; ribosome recycling factor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fsr; MFS transporter, FSR family, fosmidomycin resistance protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
FTR, FTH1, efeU; high-affinity iron transporter	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsA; cell division protein FtsA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsE; cell division transport system ATP-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsH, hflB; cell division protease FtsH [EC:3.4.24.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsK, spoIIIE; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsW, spoVE; cell division protein FtsW	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsX; cell division transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsY; fused signal recognition particle receptor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ftsZ; cell division protein FtsZ	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fusA, GFM, EFG; elongation factor G	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
fxsA; UPF0716 protein FxsA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gatA, QRSL1; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gatB, PET112; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gatC, GATC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GCH1, folE; GTP cyclohydrolase IA [EC:3.5.4.16]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gcpE, ispG; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gidA, mnmG, MTO1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gidB, rsmG; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glmM; phosphoglucosamine mutase [EC:5.4.2.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glmS, GFPT; glucosamine—fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glnA, GLUL; glutamine synthetase [EC:6.3.1.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glxK, garK; glycerate 2-kinase [EC:2.7.1.165]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gmhA, lpcA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gmhC, hldE, waaE, rfaE; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gmhD, rfaD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
greA; transcription elongation factor GreA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
groEL, HSPD1; chaperonin GroEL	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
groES, HSPE1; chaperonin GroES	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
GRPE; molecular chaperone GrpE	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gspD; general secretion pathway protein D	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gspE; general secretion pathway protein E	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gspF; general secretion pathway protein F	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gyrA; DNA gyrase subunit A [EC:5.99.1.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
gyrB; DNA gyrase subunit B [EC:5.99.1.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hcp; hydroxylamine reductase [EC:1.7.99.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hcp; type VI secretion system secreted protein Hcp	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hdhA; 7-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.159]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hemA; glutamyl-tRNA reductase [EC:1.2.1.70]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hemB, ALAD; porphobilinogen synthase [EC:4.2.1.24]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hemC, HMBS; hydroxymethylbilane synthase [EC:2.5.1.61]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hemD, UROS; uroporphyrinogen-III synthase [EC:4.2.1.75]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hemE, UROD; uroporphyrinogen decarboxylase [EC:4.1.1.37]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hemK, prmC, HEMK; release factor glutamine methyltransferase [EC:2.1.1.297]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
HINT1, hinT, hit; histidine triad (HIT) family protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hisD; histidinol dehydrogenase [EC:1.1.1.23]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hisF; cyclase [EC:4.1.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hisH; glutamine amidotransferase [EC:2.4.2.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hisIE; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase [EC:3.6.1.31 3.5.4.19]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
holA; DNA polymerase III subunit delta [EC:2.7.7.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
holB; DNA polymerase III subunit delta’ [EC:2.7.7.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hprA; glycerate dehydrogenase [EC:1.1.1.29]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hrcA; heat-inducible transcriptional repressor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hsdM; type I restriction enzyme M protein [EC:2.1.1.72]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hslU; ATP-dependent HslUV protease ATP-binding subunit HslU	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hslV, clpQ; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
HSP90A, htpG; molecular chaperone HtpG	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hspR; MerR family transcriptional regulator, heat shock protein HspR	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
htpX; heat shock protein HtpX [EC:3.4.24.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hupB; DNA-binding protein HU-beta	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hyaC; Ni/Fe-hydrogenase 1 B-type cytochrome subunit	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hyaD, hybD; hydrogenase maturation protease [EC:3.4.23.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hycH; formate hydrogenlyase maturation protein HycH	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hycI; hydrogenase 3 maturation protease [EC:3.4.23.51]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hydA; quinone-reactive Ni/Fe-hydrogenase small subunit [EC:1.12.5.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hydB; quinone-reactive Ni/Fe-hydrogenase large subunit [EC:1.12.5.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hyfA; hydrogenase-4 component A [EC:1.-.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hyfB; hydrogenase-4 component B [EC:1.-.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hyfC; hydrogenase-4 component C [EC:1.-.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hyfE; hydrogenase-4 component E [EC:1.-.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hyfF; hydrogenase-4 component F [EC:1.-.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hypA, hybF; hydrogenase nickel incorporation protein HypA/HybF	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hypB; hydrogenase nickel incorporation protein HypB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hypC; hydrogenase expression/formation protein HypC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hypD; hydrogenase expression/formation protein HypD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hypE; hydrogenase expression/formation protein HypE	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
hypF; hydrogenase maturation protein HypF	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
impB; type VI secretion system protein ImpB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
impC; type VI secretion system protein ImpC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
impG, vasA; type VI secretion system protein ImpG	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
impH, vasB; type VI secretion system protein ImpH	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
impJ, vasE; type VI secretion system protein ImpJ	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
impK, ompA, vasF, dotU; type VI secretion system protein ImpK	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
infA; translation initiation factor IF-1	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
infB, MTIF2; translation initiation factor IF-2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
infC, MTIF3; translation initiation factor IF-3	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
int; integrase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
iscS, NFS1; cysteine desulfurase [EC:2.8.1.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:2.7.7.60 4.6.1.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
jag; spoIIIJ-associated protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K02481; two-component system, NtrC family, response regulator	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K02482; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K06867; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K06872; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K06894; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K06921; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K06923; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K06940; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K06950; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K06960; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07003; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07005; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07007; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07017; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07023; putative hydrolases of HD superfamily	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07058; membrane protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07080; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07082; UPF0755 protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07088; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07097; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07098; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07100; putative phosphoribosyl transferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07112; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07118; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07124; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07164; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07166; ACT domain-containing protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07223; putative iron-dependent peroxidase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07270; glycosyl transferase, family 25	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07457; endonuclease III related protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K07501; 3’-5’ exonuclease	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K08303; putative protease [EC:3.4.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K08973; putative membrane protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09117; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09157; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09747; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09778; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09792; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09794; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09798; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09804; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09860; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09861; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09925; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09935; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09944; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09974; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K09979; uncharacterized protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K11905; type VI secretion system protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K13819; NifU-like protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K15977; putative oxidoreductase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
K18284; adenosylhomocysteine/aminodeoxyfutalosine nucleosidase [EC:3.2.2.9 3.2.2.30]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
KAE1, tsaD, QRI7; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
kch, trkA, mthK, pch; voltage-gated potassium channel	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
kdsD, kpsF; arabinose-5-phosphate isomerase [EC:5.3.1.13]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
kdtA, waaA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
korB, oorB, oforB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
korC, oorC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
korD, oorD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lapB; ATP-binding cassette, subfamily C, bacterial LapB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lapC; membrane fusion protein, adhesin transport system	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lapE; outer membrane protein, adhesin transport system	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
legF, ptmB; CMP-N,N’-diacetyllegionaminic acid synthase [EC:2.7.7.82]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
legG, neuC2; GDP/UDP-N,N’-diacetylbacillosamine 2-epimerase (hydrolysing) [EC:3.2.1.184]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
legI, neuB2; N,N’-diacetyllegionaminate synthase [EC:2.5.1.101]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lepA; GTP-binding protein LepA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lepB; signal peptidase I [EC:3.4.21.89]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
leuB, IMDH; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
leuC, IPMI-L; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lgt, umpA; phosphatidylglycerol:prolipoprotein diacylglycerol transferase [EC:2.-.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
linN; cholesterol transport system auxiliary component	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lnt; apolipoprotein N-acyltransferase [EC:2.3.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lolA; outer membrane lipoprotein carrier protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lon; ATP-dependent Lon protease [EC:3.4.21.53]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lptA; lipopolysaccharide export system protein LptA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lptB; lipopolysaccharide export system ATP-binding protein [EC:3.6.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lptD, imp, ostA; LPS-assembly protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lptF; lipopolysaccharide export system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lptG; lipopolysaccharide export system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lpxK; tetraacyldisaccharide 4’-kinase [EC:2.7.1.130]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lpxL, htrB; Kdo2-lipid IVA lauroyltransferase [EC:2.3.1.241]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lspA; signal peptidase II [EC:3.4.23.36]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
LYS5, acpT; 4’-phosphopantetheinyl transferase [EC:2.7.8.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lysA; diaminopimelate decarboxylase [EC:4.1.1.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lysC; aspartate kinase [EC:2.7.2.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
lysE, argO; L-lysine exporter family protein LysE/ArgO	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
macA; membrane fusion protein, macrolide-specific efflux system	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
macB; macrolide transport system ATP-binding/permease protein [EC:3.6.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
maf; septum formation protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
map; methionyl aminopeptidase [EC:3.4.11.18]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mcrC; 5-methylcytosine-specific restriction enzyme subunit McrC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mdaB; modulator of drug activity B	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mdh; malate dehydrogenase [EC:1.1.1.37]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
merP; periplasmic mercuric ion binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
merT; mercuric ion transport protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
metC; cystathionine beta-lyase [EC:4.4.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
metE; 5-methyltetrahydropteroyltriglutamate–homocysteine methyltransferase [EC:2.1.1.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
metI; D-methionine transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
metK; S-adenosylmethionine synthetase [EC:2.5.1.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
metN; D-methionine transport system ATP-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mfd; transcription-repair coupling factor (superfamily II helicase) [EC:3.6.4.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mgtE; magnesium transporter	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
miaA, TRIT1; tRNA dimethylallyltransferase [EC:2.5.1.75]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mlaA, vacJ; phospholipid-binding lipoprotein MlaA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mlaC; phospholipid transport system substrate-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mlaD, linM; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mlaE, linK; phospholipid/cholesterol/gamma-HCH transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mlaF, linL, mkl; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mltD, dniR; membrane-bound lytic murein transglycosylase D [EC:4.2.2.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mnmE, trmE, MSS1; tRNA modification GTPase [EC:3.6.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
moaA, CNX2; GTP 3’,8-cyclase [EC:4.1.99.22]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
moaC, CNX3; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
moaD, cysO; sulfur-carrier protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
MOCS2B, moaE; molybdopterin synthase catalytic subunit [EC:2.8.1.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
modC; molybdate transport system ATP-binding protein [EC:3.6.3.29]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
modD; molybdenum transport protein [EC:2.4.2.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
motA; chemotaxis protein MotA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mqnA; chorismate dehydratase [EC:4.2.1.151]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mqnD; 1,4-dihydroxy-6-naphthoate synthase [EC:1.14.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mqo; malate dehydrogenase (quinone) [EC:1.1.5.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mraW, rsmH; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mrcA; penicillin-binding protein 1A [EC:2.4.1.129 3.4.16.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mrdA; penicillin-binding protein 2 [EC:3.4.16.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mreC; rod shape-determining protein MreC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mrp, NUBPL; ATP-binding protein involved in chromosome partitioning	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mrr; restriction system protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:3.6.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mscL; large conductance mechanosensitive channel	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
MTFMT, fmt; methionyl-tRNA formyltransferase [EC:2.1.2.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murC; UDP-N-acetylmuramate–alanine ligase [EC:6.3.2.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murD; UDP-N-acetylmuramoylalanine–D-glutamate ligase [EC:6.3.2.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase [EC:6.3.2.13]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murF; UDP-N-acetylmuramoyl-tripeptide–D-alanyl-D-alanine ligase [EC:6.3.2.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murG; UDP-N-acetylglucosamine–N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murI; glutamate racemase [EC:5.1.1.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
murJ, mviN; putative peptidoglycan lipid II flippase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
mutS2; DNA mismatch repair protein MutS2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nadE; NAD+ synthase [EC:6.3.1.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
napA; periplasmic nitrate reductase NapA [EC:1.7.99.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
napB; cytochrome c-type protein NapB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
napC; cytochrome c-type protein NapC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
napD; periplasmic nitrate reductase NapD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
napF; ferredoxin-type protein NapF	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ncd2, npd; nitronate monooxygenase [EC:1.13.12.16]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ndk, NME; nucleoside-diphosphate kinase [EC:2.7.4.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
neuA; N-acylneuraminate cytidylyltransferase [EC:2.7.7.43]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nfo; deoxyribonuclease IV [EC:3.1.21.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nhaC; Na+:H+ antiporter, NhaC family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nifB; nitrogen fixation protein NifB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nikR; CopG family transcriptional regulator, nickel-responsive regulator	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
norB; nitric oxide reductase subunit B [EC:1.7.2.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nosD; nitrous oxidase accessory protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nosZ; nitrous-oxide reductase [EC:1.7.2.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nrfC; protein NrfC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nrfD; protein NrfD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
NTH; endonuclease III [EC:4.2.99.18]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
NUDT14; UDP-sugar diphosphatase [EC:3.6.1.45]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoA; NADH-quinone oxidoreductase subunit A [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoB; NADH-quinone oxidoreductase subunit B [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoC; NADH-quinone oxidoreductase subunit C [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoD; NADH-quinone oxidoreductase subunit D [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoE; NADH-quinone oxidoreductase subunit E [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoF; NADH-quinone oxidoreductase subunit F [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoG; NADH-quinone oxidoreductase subunit G [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoH; NADH-quinone oxidoreductase subunit H [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoI; NADH-quinone oxidoreductase subunit I [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoJ; NADH-quinone oxidoreductase subunit J [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoK; NADH-quinone oxidoreductase subunit K [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoL; NADH-quinone oxidoreductase subunit L [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoM; NADH-quinone oxidoreductase subunit M [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nuoN; NADH-quinone oxidoreductase subunit N [EC:1.6.5.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nusA; N utilization substance protein A	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nusB; N utilization substance protein B	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
nusG; transcriptional antiterminator NusG	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
obgE, cgtA; GTPase [EC:3.6.5.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ogt, MGMT; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
oprM, emhC, ttgC, cusC, adeK, smeF, mtrE, cmeC, gesC; outer membrane protein, multidrug efflux system	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
osmY; hyperosmotically inducible periplasmic protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
p19, ftrA; periplasmic iron binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pal; peptidoglycan-associated lipoprotein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
panC; pantoate–beta-alanine ligase [EC:6.3.2.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
panD; aspartate 1-decarboxylase [EC:4.1.1.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
parA, soj; chromosome partitioning protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
parB, spo0J; chromosome partitioning protein, ParB family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pat; phosphinothricin acetyltransferase [EC:2.3.1.183]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
patB, malY; cystathione beta-lyase [EC:4.4.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pbpC; penicillin-binding protein 1C [EC:2.4.1.129]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pbuG; putative MFS transporter, AGZA family, xanthine/uracil permease	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pccA; periplasmic copper chaperone A	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PDF, def; peptide deformylase [EC:3.5.1.88]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pdxK, pdxY; pyridoxine kinase [EC:2.7.1.35]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pepD; dipeptidase D [EC:3.4.13.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pepF, pepB; oligoendopeptidase F [EC:3.4.24.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pepT; tripeptide aminopeptidase [EC:3.4.11.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
perR; Fur family transcriptional regulator, peroxide stress response regulator	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pflA, pflC, pflE; pyruvate formate lyase activating enzyme [EC:1.97.1.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pglA; N,N’-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase [EC:2.4.1.290]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pglC; undecaprenyl phosphate N,N’-diacetylbacillosamine 1-phosphate transferase [EC:2.7.8.36]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pglD; UDP-N-acetylbacillosamine N-acetyltransferase [EC:2.3.1.203]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pglE; UDP-N-acetylbacillosamine transaminase [EC:2.6.1.34]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pglF; UDP-N-acetyl-D-glucosamine 4,6-dehydratase [EC:4.2.1.135]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pglI; GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase [EC:2.4.1.293]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pglJ; N-acetylgalactosamine-N,N’-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase [EC:2.4.1.291]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pgsA, PGS1; CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
phsA, psrA; thiosulfate reductase / polysulfide reductase chain A [EC:1.8.5.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pilD, pppA; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PK, pyk; pyruvate kinase [EC:2.7.1.40]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
plsX; glycerol-3-phosphate acyltransferase PlsX [EC:2.3.1.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
plsY; glycerol-3-phosphate acyltransferase PlsY [EC:2.3.1.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pncB, NAPRT1; nicotinate phosphoribosyltransferase [EC:6.3.4.21]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
polA; DNA polymerase I [EC:2.7.7.7]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ppa; inorganic pyrophosphatase [EC:3.6.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pphA; serine/threonine protein phosphatase 1 [EC:3.1.3.16]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ppk; polyphosphate kinase [EC:2.7.4.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ppnK, NADK; NAD+ kinase [EC:2.7.1.23]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ppnN; pyrimidine/purine-5’-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pqqL; zinc protease [EC:3.4.24.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
prdX, proX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PRDX2_4, ahpC; peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
prfA, MTRF1, MRF1; peptide chain release factor 1	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
prfB; peptide chain release factor 2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
priA; primosomal protein N’ (replication factor Y) (superfamily II helicase) [EC:3.6.4.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pseB; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.115]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pseC; UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine transaminase [EC:2.6.1.92]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pseF; pseudaminic acid cytidylyltransferase [EC:2.7.7.81]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pseG; UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase [EC:3.6.1.57]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pseH; UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase [EC:2.3.1.202]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pseI, neuB3; pseudaminic acid synthase [EC:2.5.1.97]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
psrB; polysulfide reductase chain B	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
psrC; polysulfide reductase chain C	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pta; phosphate acetyltransferase [EC:2.3.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
PTH1, pth, spoVC; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purD; phosphoribosylamine—glycine ligase [EC:6.3.4.13]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
putP; sodium/proline symporter	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pyrB, PYR2; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pyrF; orotidine-5’-phosphate decarboxylase [EC:4.1.1.23]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pyrG, CTPS; CTP synthase [EC:6.3.4.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pyrH; uridylate kinase [EC:2.7.4.22]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
pyrP, uraA; uracil permease	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
queH; epoxyqueuosine reductase [EC:1.17.99.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
racD; aspartate racemase [EC:5.1.1.13]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
radA, sms; DNA repair protein RadA/Sms	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rbfA; ribosome-binding factor A	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
recA; recombination protein RecA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
recG; ATP-dependent DNA helicase RecG [EC:3.6.4.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
recN; DNA repair protein RecN (Recombination protein N)	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
recR; recombination protein RecR	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
relA; GTP pyrophosphokinase [EC:2.7.6.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
relE, stbE; mRNA interferase RelE/StbE	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rho; transcription termination factor Rho	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ribA, RIB1; GTP cyclohydrolase II [EC:3.5.4.25]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ribE, RIB5; riboflavin synthase [EC:2.5.1.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ribH, RIB4; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ridA, tdcF, RIDA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rimM; 16S rRNA processing protein RimM	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rimP; ribosome maturation factor RimP	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rlmB; 23S rRNA (guanosine2251-2’-O)-methyltransferase [EC:2.1.1.185]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rlpA; rare lipoprotein A	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rmuC; DNA recombination protein RmuC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rnhB; ribonuclease HII [EC:3.1.26.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rnj; ribonuclease J [EC:3.1.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rnr, vacB; ribonuclease R [EC:3.1.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rny; ribonucrease Y [EC:3.1.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rodA, mrdB; rod shape determining protein RodA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L1, MRPL1, rplA; large subunit ribosomal protein L1	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L11, MRPL11, rplK; large subunit ribosomal protein L11	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L13, MRPL13, rplM; large subunit ribosomal protein L13	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L14, MRPL14, rplN; large subunit ribosomal protein L14	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L15, MRPL15, rplO; large subunit ribosomal protein L15	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L16, MRPL16, rplP; large subunit ribosomal protein L16	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L18, MRPL18, rplR; large subunit ribosomal protein L18	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L19, MRPL19, rplS; large subunit ribosomal protein L19	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L2, MRPL2, rplB; large subunit ribosomal protein L2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L20, MRPL20, rplT; large subunit ribosomal protein L20	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L21, MRPL21, rplU; large subunit ribosomal protein L21	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L22, MRPL22, rplV; large subunit ribosomal protein L22	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L23, MRPL23, rplW; large subunit ribosomal protein L23	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L24, MRPL24, rplX; large subunit ribosomal protein L24	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L25, rplY; large subunit ribosomal protein L25	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L27, MRPL27, rpmA; large subunit ribosomal protein L27	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L29, rpmC; large subunit ribosomal protein L29	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L3, MRPL3, rplC; large subunit ribosomal protein L3	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L31, rpmE; large subunit ribosomal protein L31	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L32, MRPL32, rpmF; large subunit ribosomal protein L32	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L33, MRPL33, rpmG; large subunit ribosomal protein L33	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L34, MRPL34, rpmH; large subunit ribosomal protein L34	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L35, MRPL35, rpmI; large subunit ribosomal protein L35	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L4, MRPL4, rplD; large subunit ribosomal protein L4	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L5, MRPL5, rplE; large subunit ribosomal protein L5	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L6, MRPL6, rplF; large subunit ribosomal protein L6	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-L9, MRPL9, rplI; large subunit ribosomal protein L9	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S1, rpsA; small subunit ribosomal protein S1	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S10, MRPS10, rpsJ; small subunit ribosomal protein S10	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S13, rpsM; small subunit ribosomal protein S13	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S14, MRPS14, rpsN; small subunit ribosomal protein S14	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S17, MRPS17, rpsQ; small subunit ribosomal protein S17	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S19, rpsS; small subunit ribosomal protein S19	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S20, rpsT; small subunit ribosomal protein S20	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S21, MRPS21, rpsU; small subunit ribosomal protein S21	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S3, rpsC; small subunit ribosomal protein S3	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S4, rpsD; small subunit ribosomal protein S4	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S8, rpsH; small subunit ribosomal protein S8	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rpe, RPE; ribulose-phosphate 3-epimerase [EC:5.1.3.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rpoC; DNA-directed RNA polymerase subunit beta’ [EC:2.7.7.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rpoD; RNA polymerase primary sigma factor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rpoN; RNA polymerase sigma-54 factor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rseP; regulator of sigma E protease [EC:3.4.24.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rsmI; 16S rRNA (cytidine1402-2’-O)-methyltransferase [EC:2.1.1.198]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
rtpR; ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ruvA; holliday junction DNA helicase RuvA [EC:3.6.4.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ruvB; holliday junction DNA helicase RuvB [EC:3.6.4.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.22.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ruvX; putative holliday junction resolvase [EC:3.1.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
SAM50, TOB55, bamA; outer membrane protein insertion porin family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sat, met3; sulfate adenylyltransferase [EC:2.7.7.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sbmA, bacA; peptide/bleomycin uptake transporter	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
SCO1_2; protein SCO1/2	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sdhA, frdA; succinate dehydrogenase / fumarate reductase, flavoprotein subunit [EC:1.3.5.1 1.3.5.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sdhB, frdB; succinate dehydrogenase / fumarate reductase, iron-sulfur subunit [EC:1.3.5.1 1.3.5.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sdhC, frdC; succinate dehydrogenase / fumarate reductase, cytochrome b subunit	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
secA; preprotein translocase subunit SecA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
secD; preprotein translocase subunit SecD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
secE; preprotein translocase subunit SecE	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
secF; preprotein translocase subunit SecF	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
secG; preprotein translocase subunit SecG	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
secY; preprotein translocase subunit SecY	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
selB, EEFSEC; selenocysteine-specific elongation factor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
selD, SEPHS; selenide, water dikinase [EC:2.7.9.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
selU; tRNA 2-selenouridine synthase [EC:2.9.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
serB, PSPH; phosphoserine phosphatase [EC:3.1.3.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sixA; phosphohistidine phosphatase [EC:3.1.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
slt; soluble lytic murein transglycosylase [EC:4.2.2.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
smf; DNA processing protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
smpB; SsrA-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sotB; MFS transporter, DHA1 family, L-arabinose/isopropyl-beta-D-thiogalactopyranoside export protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
speA; arginine decarboxylase [EC:4.1.1.19]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sppA; protease IV [EC:3.4.21.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
SRP54, ffh; signal recognition particle subunit SRP54 [EC:3.6.5.4]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ssb; single-strand DNA-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
sstT; serine/threonine transporter	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ssuA; sulfonate transport system substrate-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ssuB; sulfonate transport system ATP-binding protein [EC:3.6.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ssuC; sulfonate transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
stbD; antitoxin StbD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
STE24; STE24 endopeptidase [EC:3.4.24.84]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
surE; 5’-nucleotidase [EC:3.1.3.5]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tatA; sec-independent protein translocase protein TatA	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tatB; sec-independent protein translocase protein TatB	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tatC; sec-independent protein translocase protein TatC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tatD; TatD DNase family protein [EC:3.1.21.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.BAT1; bacterial/archaeal transporter family protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.CPA1; monovalent cation:H+ antiporter, CPA1 family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.DCUC, dcuC, dcuD; C4-dicarboxylate transporter, DcuC family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.FEV.OM; iron complex outermembrane recepter protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.FEV.OM1, fhuE, fpvA, fptA; outer-membrane receptor for ferric coprogen and ferric-rhodotorulic acid	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.GNTP; gluconate:H+ symporter, GntP family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.KEF; monovalent cation:H+ antiporter-2, CPA2 family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.OOP; OmpA-OmpF porin, OOP family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TC.PIT; inorganic phosphate transporter, PiT family	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tgt, QTRT1; queuine tRNA-ribosyltransferase [EC:2.4.2.29]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thiG; thiazole synthase [EC:2.8.1.10]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thiH; 2-iminoacetate synthase [EC:4.1.99.19]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thiJ; protein deglycase [EC:3.5.1.124]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thiL; thiamine-monophosphate kinase [EC:2.7.4.16]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thiS; sulfur carrier protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thrB1; homoserine kinase [EC:2.7.1.39]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tig; trigger factor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tilS, mesJ; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tlyA; 23S rRNA (cytidine1920-2’-O)/16S rRNA (cytidine1409-2’-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tmk, DTYMK; dTMP kinase [EC:2.7.4.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tolB; TolB protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
topA; DNA topoisomerase I [EC:5.99.1.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tpx; thiol peroxidase, atypical 2-Cys peroxiredoxin [EC:1.11.1.15]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trmB, METTL1; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trmL, cspR; tRNA (cytidine/uridine-2’-O-)-methyltransferase [EC:2.1.1.207]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trpA; tryptophan synthase alpha chain [EC:4.2.1.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trpB; tryptophan synthase beta chain [EC:4.2.1.20]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trpE; anthranilate synthase component I [EC:4.1.3.27]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trpGD; anthranilate synthase/phosphoribosyltransferase [EC:4.1.3.27 2.4.2.18]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
truA, PUS1; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
truB, PUS4, TRUB1; tRNA pseudouridine55 synthase [EC:5.4.99.25]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
truD, PUS7; tRNA pseudouridine13 synthase [EC:5.4.99.27]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
trxA; thioredoxin 1	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tsf, TSFM; elongation factor Ts	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tspA; uncharacterized membrane protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ttdA; L(+)-tartrate dehydratase alpha subunit [EC:4.2.1.32]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ttdB; L(+)-tartrate dehydratase beta subunit [EC:4.2.1.32]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ttrA; tetrathionate reductase subunit A	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ttrB; tetrathionate reductase subunit B	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tuf, TUFM; elongation factor Tu	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tupA, vupA; tungstate transport system substrate-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tupB, vupB; tungstate transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tupC, vupC; tungstate transport system ATP-binding protein [EC:3.6.3.55]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
typA, bipA; GTP-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
tyrA2; prephenate dehydrogenase [EC:1.3.1.12]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ubiX, bsdB, PAD1; flavin prenyltransferase [EC:2.5.1.129]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UGDH, ugd; UDPglucose 6-dehydrogenase [EC:1.1.1.22]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UGP2, galU, galF; UTP–glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
umuC; DNA polymerase V	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UNG, UDG; uracil-DNA glycosylase [EC:3.2.2.27]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
upp, UPRT; uracil phosphoribosyltransferase [EC:2.4.2.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
URA4, pyrC; dihydroorotase [EC:3.5.2.3]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
uup; ABC transport system ATP-binding/permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
uvrA; excinuclease ABC subunit A	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
uvrB; excinuclease ABC subunit B	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
uvrC; excinuclease ABC subunit C	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
vasD, lip; type VI secretion system protein VasD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
vasJ; type VI secretion system protein VasJ	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
vgrG; type VI secretion system secreted protein VgrG	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
waaC, rfaC; heptosyltransferase I [EC:2.4.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
waaF, rfaF; heptosyltransferase II [EC:2.4.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
waaG, rfaG; UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC:2.4.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
waaQ, rfaQ; heptosyltransferase III [EC:2.4.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
wbpO; UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
xerD; integrase/recombinase XerD	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yafQ; mRNA interferase YafQ [EC:3.1.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yagU; putative membrane protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yajC; preprotein translocase subunit YajC	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yajG; uncharacterized lipoprotein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yajQ; cyclic-di-GMP-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ybaK, ebsC; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ybeY, yqfG; probable rRNA maturation factor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ycaJ; putative ATPase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yccA; modulator of FtsH protease	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ychF; ribosome-binding ATPase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ychN; uncharacterized protein involved in oxidation of intracellular sulfur	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yfiH; polyphenol oxidase [EC:1.10.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yggS, PROSC; PLP dependent protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yggT; YggT family protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yhbH; putative sigma-54 modulation protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yhcO; ribonuclease inhibitor	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yidC, spoIIIJ, OXA1, ccfA; YidC/Oxa1 family membrane protein insertase	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ykkC; paired small multidrug resistance pump	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ykkD; paired small multidrug resistance pump	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
ynaI, mscMJ; MscS family membrane protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yoeB; toxin YoeB [EC:3.1.-.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yojI; multidrug/microcin transport system ATP-binding/permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yraN; putative endonuclease	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
yuiF; putative amino acid transporter	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
znuA; zinc transport system substrate-binding protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
znuB; zinc transport system permease protein	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
znuC; zinc transport system ATP-binding protein [EC:3.6.3.-]	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738
zur; Fur family transcriptional regulator, zinc uptake regulator	0.52532	0.15648	0.64615	3.701	0.23862	65	0.44086	4.010	0.20765	93	0.31632	0.64901	141.28	0.51738	0.51738

plot.dat <- tb.ra %>%
  arrange(p) %>%
  slice_head(n=50)%>%
  mutate(
    description = fct_reorder(description, `Overall Mean`),
    description = factor(description, levels = levels(description), ordered=T)
  ) %>%
  arrange(description) %>%
  mutate(
    id = 1:n(),
    step = ifelse(id%%2 == 0, 1, 0),
    Mean_diff = `Tumor Mean` - `Non-Tumor Mean`,
    diff_se = SEpooled,
    Mean_diff_ll = Mean_diff - qt(0.975, df)*diff_se,
    Mean_diff_ul = Mean_diff + qt(0.975, df)*diff_se
  ) %>%
  pivot_longer(
    cols=contains("Mean"),
    names_to = "group",
    values_to = "mean"
  )



p1.d <- plot.dat %>%
  filter(group %in% c("Tumor Mean","Non-Tumor Mean")) %>%
  mutate(
    group = ifelse(group == "Tumor Mean", "Tumor", "Non-Tumor"),
    col = ifelse(step == 1, "grey90", "white"),
    h=1, w=Inf
    
  )
p1 <- ggplot()+
  geom_tile(data = p1.d,
              aes(y = description, x=0,
                  height=h, width=w),
              fill = p1.d$col, color=p1.d$col)+
    geom_bar(data=p1.d,
             aes(x=mean, y=description,
                 group=group, color=group,
                 fill=group),
             stat="identity",position = "dodge",
             alpha = 1)+
    labs(x="Mean Abundance")+
    theme_classic()+
    theme(
      legend.position = "bottom",
      plot.margin = unit(c(1,0,1,1), "lines")
    )

p2.d <- plot.dat %>%
  filter(group %in% c("Mean_diff", "Mean_diff_ll", "Mean_diff_ul")) %>%
  pivot_wider(
    names_from = group,
    values_from = mean
  ) %>%
  mutate(
    group = ifelse(Mean_diff > 0, "Tumor", "Non-Tumor"),
    p = sprintf("%.3f", round(p,3)),
    ll = min(Mean_diff_ll)-0.01,
    ul = max(Mean_diff_ul)+0.01
  )
p2<-ggplot(p2.d, aes(x=Mean_diff, y=description))+
    geom_tile(data = p1.d,
              aes(y = description, x=0,
                  height=h, width=w),
              fill = p1.d$col, color=p1.d$col)+
    geom_vline(xintercept = 0, linetype="dashed", alpha=0.5)+
    geom_segment(aes(x=Mean_diff_ll, y=description, xend=Mean_diff_ul, yend=description))+
    geom_point(aes(fill=group, color=group))+
    geom_text(aes(label=p, x=unique(ul)+0.1))+
    coord_cartesian(xlim = c(unique(p2.d$ll), unique(p2.d$ul)),
                    clip = 'off') +
    annotate("text", x=unique(p2.d$ul)+0.2,y = 25,
             angle=90,
             label="p-value (uncorrected)")+
    labs(x="Mean Difference in Abundance")+
    theme_classic()+
    theme(
      legend.position = "bottom",
      axis.title.y = element_blank(),
      axis.text.y = element_blank(),
      axis.line.y = element_blank(),
      axis.ticks.y = element_blank(),
      plot.margin = unit(c(1,4,1,0), "lines")
    )

# plot
p1 + p2 +
  plot_annotation(title="Stratefied KO Data - Campylobacter concisus: First 50 descriptions with lowest p-value (uncorrected)")

Modeling Difference between Tumor and Non-Tumor

For the modeling, we used a generalized linear mixed model (GLMM).

First, we looked at the biserial correlation between the abundance of each description and the tumor status.

tb <- mydata %>%
  group_by(description)%>%
  summarise(
    r = cor(tumor, Abundance)
  ) %>%
  mutate(
    M=mean(r)
  )

ggplot(tb, aes(x=r))+
  geom_density()+
  geom_vline(aes(xintercept = M))+
  labs(x="Biserial Correlation",title="Relationship between description abundance and tumor (tumor vs. non-tumor)")+
  theme(panel.grid = element_blank())

Next, we need the data to be on an interpretable scale. First, let’s use the raw abundance like scale.

p <- ggplot(mydata, aes(x=Abundance))+
  geom_density()
p

mydata <- mydata %>%
  mutate(Abundance.dich=ifelse(Abundance==0, 0, 1))
table(mydata$Abundance.dich)

     0      1 
137350  24600 

Let’s first run models by description so that we can avoid the nesting issue initially. We will come back to this to conduct the final model (it will be more powerful).

DESCRIPTIONS <- unique(mydata$description)
i<-1
dat0 <- mydata %>% filter(description==DESCRIPTIONS[i])

# quasipossion (approximately negative binom) give an approx. answer.
fit0 <- glm(
  Abundance ~ 1 + tumor,
  data= dat0,
  family=quasipoisson(link = "log")
)
summary(fit0)

Call:
glm(formula = Abundance ~ 1 + tumor, family = quasipoisson(link = "log"), 
    data = dat0)

Deviance Residuals: 
   Min      1Q  Median      3Q     Max  
-1.137  -1.137  -0.939  -0.939   9.542  

Coefficients:
            Estimate Std. Error t value Pr(>|t|)  
(Intercept)   -0.819      0.434   -1.89    0.061 .
tumor          0.382      0.610    0.63    0.532  
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

(Dispersion parameter for quasipoisson family taken to be 7.7141)

    Null deviance: 387.36  on 157  degrees of freedom
Residual deviance: 384.34  on 156  degrees of freedom
AIC: NA

Number of Fisher Scoring iterations: 7

NExt, let’s model the percent relative abundance. This will allow us to make inference about the difference average relative abundance. Which is a simpler interpretation than trying to model differences in the log relative abundance which will need to be interpreted as the multiplicative relative change.

results.out <- as.data.frame(matrix(ncol=4, nrow=length(DESCRIPTIONS)))
colnames(results.out) <- c("description", "Est", "SE", "p")
#results.out$description <-DESCRIPTIONS

i <- 1
for(i in 1:length(DESCRIPTIONS)){
#for(i in 1:5){ 
  dat0 <- mydata %>%
    filter(description == DESCRIPTIONS[i])
  fit0 <- glm(
  Abundance ~ 1 + tumor,
  data= dat0,
  family=quasipoisson(link = "log")
)
  fit.sum <- summary(fit0)
  results.out[i, 1] <- DESCRIPTIONS[i]
  results.out[i, 2:4] <- fit.sum$coefficients[2, c(1,2,4)]
}

results.out$fdr_p <- p.adjust(results.out$p, method="fdr")

kable(results.out, format="html", digits=3) %>%
  kable_styling(full_width = T)%>%
  scroll_box(width="100%", height="600px")

description	Est	SE	p	fdr_p
AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]	0.382	0.61	0.532	0.532
aas; acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase / long-chain-fatty-acid–[acyl-carrier-protein] ligase [EC:2.3.1.40 6.2.1.20]	0.382	0.61	0.532	0.532
ABC-2.A; ABC-2 type transport system ATP-binding protein	0.382	0.61	0.532	0.532
ABC-2.P; ABC-2 type transport system permease protein	0.382	0.61	0.532	0.532
ABC.CD.A; putative ABC transport system ATP-binding protein	0.382	0.61	0.532	0.532
ABC.CD.P; putative ABC transport system permease protein	0.382	0.61	0.532	0.532
ABC.CYST.A; cystine transport system ATP-binding protein [EC:3.6.3.-]	0.382	0.61	0.532	0.532
ABC.CYST.P; cystine transport system permease protein	0.382	0.61	0.532	0.532
ABC.FEV.A; iron complex transport system ATP-binding protein [EC:3.6.3.34]	0.382	0.61	0.532	0.532
ABC.FEV.P; iron complex transport system permease protein	0.382	0.61	0.532	0.532
ABC.FEV.S; iron complex transport system substrate-binding protein	0.382	0.61	0.532	0.532
ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:3.6.3.21]	0.382	0.61	0.532	0.532
ABC.PA.P; polar amino acid transport system permease protein	0.382	0.61	0.532	0.532
ABC.PA.S; polar amino acid transport system substrate-binding protein	0.382	0.61	0.532	0.532
ABC.PE.A1; peptide/nickel transport system ATP-binding protein	0.382	0.61	0.532	0.532
ABC.PE.P; peptide/nickel transport system permease protein	0.382	0.61	0.532	0.532
ABC.PE.P1; peptide/nickel transport system permease protein	0.382	0.61	0.532	0.532
ABC.PE.S; peptide/nickel transport system substrate-binding protein	0.382	0.61	0.532	0.532
abgA; aminobenzoyl-glutamate utilization protein A	0.382	0.61	0.532	0.532
accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]	0.382	0.61	0.532	0.532
accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein	0.382	0.61	0.532	0.532
accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]	0.382	0.61	0.532	0.532
accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]	0.382	0.61	0.532	0.532
ackA; acetate kinase [EC:2.7.2.1]	0.382	0.61	0.532	0.532
acnB; aconitate hydratase 2 / 2-methylisocitrate dehydratase [EC:4.2.1.3 4.2.1.99]	0.382	0.61	0.532	0.532
acpP; acyl carrier protein	0.382	0.61	0.532	0.532
acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]	0.382	0.61	0.532	0.532
acrA, mexA, adeI, smeD, mtrC, cmeA; membrane fusion protein, multidrug efflux system	0.382	0.61	0.532	0.532
acrB, mexB, adeJ, smeE, mtrD, cmeB; multidrug efflux pump	0.382	0.61	0.532	0.532
ACSL, fadD; long-chain acyl-CoA synthetase [EC:6.2.1.3]	0.382	0.61	0.532	0.532
adk, AK; adenylate kinase [EC:2.7.4.3]	0.382	0.61	0.532	0.532
aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]	0.382	0.61	0.532	0.532
alaC; alanine-synthesizing transaminase [EC:2.6.1.-]	0.382	0.61	0.532	0.532
alr; alanine racemase [EC:5.1.1.1]	0.382	0.61	0.532	0.532
amiABC; N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28]	0.382	0.61	0.532	0.532
APRT, apt; adenine phosphoribosyltransferase [EC:2.4.2.7]	0.382	0.61	0.532	0.532
aqpZ; aquaporin Z	0.382	0.61	0.532	0.532
argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]	0.382	0.61	0.532	0.532
argH, ASL; argininosuccinate lyase [EC:4.3.2.1]	0.382	0.61	0.532	0.532
aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]	0.382	0.61	0.532	0.532
aroB; 3-dehydroquinate synthase [EC:4.2.3.4]	0.382	0.61	0.532	0.532
aroC; chorismate synthase [EC:4.2.3.5]	0.382	0.61	0.532	0.532
aroE; shikimate dehydrogenase [EC:1.1.1.25]	0.382	0.61	0.532	0.532
aroQ, qutE; 3-dehydroquinate dehydratase II [EC:4.2.1.10]	0.382	0.61	0.532	0.532
asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]	0.382	0.61	0.532	0.532
asnB, ASNS; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]	0.382	0.61	0.532	0.532
aspA; aspartate ammonia-lyase [EC:4.3.1.1]	0.382	0.61	0.532	0.532
aspB; aspartate aminotransferase [EC:2.6.1.1]	0.382	0.61	0.532	0.532
aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]	0.382	0.61	0.532	0.532
assT; arylsulfate sulfotransferase [EC:2.8.2.22]	0.382	0.61	0.532	0.532
ATPF0A, atpB; F-type H+-transporting ATPase subunit a	0.382	0.61	0.532	0.532
ATPF0B, atpF; F-type H+-transporting ATPase subunit b	0.382	0.61	0.532	0.532
ATPF0C, atpE; F-type H+-transporting ATPase subunit c	0.382	0.61	0.532	0.532
ATPF1A, atpA; F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]	0.382	0.61	0.532	0.532
ATPF1B, atpD; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]	0.382	0.61	0.532	0.532
ATPF1D, atpH; F-type H+-transporting ATPase subunit delta	0.382	0.61	0.532	0.532
ATPF1E, atpC; F-type H+-transporting ATPase subunit epsilon	0.382	0.61	0.532	0.532
ATPF1G, atpG; F-type H+-transporting ATPase subunit gamma	0.382	0.61	0.532	0.532
bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]	0.382	0.61	0.532	0.532
bamD; outer membrane protein assembly factor BamD	0.382	0.61	0.532	0.532
BCP, PRXQ, DOT5; peroxiredoxin Q/BCP [EC:1.11.1.15]	0.382	0.61	0.532	0.532
bcr, tcaB; MFS transporter, DHA1 family, multidrug resistance protein	0.382	0.61	0.532	0.532
bdhAB; butanol dehydrogenase [EC:1.1.1.-]	0.382	0.61	0.532	0.532
betT, betS; choline/glycine/proline betaine transport protein	0.382	0.61	0.532	0.532
bioB; biotin synthase [EC:2.8.1.6]	0.382	0.61	0.532	0.532
birA; BirA family transcriptional regulator, biotin operon repressor / biotin—[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]	0.382	0.61	0.532	0.532
carA, CPA1; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]	0.382	0.61	0.532	0.532
carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]	0.382	0.61	0.532	0.532
CARP, pepA; leucyl aminopeptidase [EC:3.4.11.1]	0.382	0.61	0.532	0.532
CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]	0.382	0.61	0.532	0.532
cas1; CRISP-associated protein Cas1	0.382	0.61	0.532	0.532
cas2; CRISPR-associated protein Cas2	0.382	0.61	0.532	0.532
cas3; CRISPR-associated endonuclease/helicase Cas3 [EC:3.1.-.- 3.6.4.-]	0.382	0.61	0.532	0.532
cas4; CRISPR-associated exonuclease Cas4 [EC:3.1.12.1]	0.382	0.61	0.532	0.532
cas5h; CRISPR-associated protein Cas5h	0.382	0.61	0.532	0.532
cbpA; curved DNA-binding protein	0.382	0.61	0.532	0.532
cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]	0.382	0.61	0.532	0.532
ccoN; cytochrome c oxidase cbb3-type subunit I [EC:1.9.3.1]	0.382	0.61	0.532	0.532
ccoO; cytochrome c oxidase cbb3-type subunit II	0.382	0.61	0.532	0.532
ccoP; cytochrome c oxidase cbb3-type subunit III	0.382	0.61	0.532	0.532
ccoQ; cytochrome c oxidase cbb3-type subunit IV	0.382	0.61	0.532	0.532
cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]	0.382	0.61	0.532	0.532
cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]	0.382	0.61	0.532	0.532
cheR; chemotaxis protein methyltransferase CheR [EC:2.1.1.80]	0.382	0.61	0.532	0.532
cheV; two-component system, chemotaxis family, chemotaxis protein CheV	0.382	0.61	0.532	0.532
cheW; purine-binding chemotaxis protein CheW	0.382	0.61	0.532	0.532
cheY; two-component system, chemotaxis family, chemotaxis protein CheY	0.382	0.61	0.532	0.532
CHO1, pssA; CDP-diacylglycerol—serine O-phosphatidyltransferase [EC:2.7.8.8]	0.382	0.61	0.532	0.532
clpB; ATP-dependent Clp protease ATP-binding subunit ClpB	0.382	0.61	0.532	0.532
clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]	0.382	0.61	0.532	0.532
clpX, CLPX; ATP-dependent Clp protease ATP-binding subunit ClpX	0.382	0.61	0.532	0.532
cmeR; TetR/AcrR family transcriptional regulator, cmeABC operon repressor	0.382	0.61	0.532	0.532
cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]	0.382	0.61	0.532	0.532
cmoB; tRNA (mo5U34)-methyltransferase [EC:2.1.1.-]	0.382	0.61	0.532	0.532
coaBC, dfp; phosphopantothenoylcysteine decarboxylase / phosphopantothenate—cysteine ligase [EC:4.1.1.36 6.3.2.5]	0.382	0.61	0.532	0.532
coaE; dephospho-CoA kinase [EC:2.7.1.24]	0.382	0.61	0.532	0.532
coaX; type III pantothenate kinase [EC:2.7.1.33]	0.382	0.61	0.532	0.532
comEA; competence protein ComEA	0.382	0.61	0.532	0.532
comEC; competence protein ComEC	0.382	0.61	0.532	0.532
comFC; competence protein ComFC	0.382	0.61	0.532	0.532
comM; magnesium chelatase family protein	0.382	0.61	0.532	0.532
copA, ATP7; Cu+-exporting ATPase [EC:3.6.3.54]	0.382	0.61	0.532	0.532
corA; magnesium transporter	0.382	0.61	0.532	0.532
cpg; glutamate carboxypeptidase [EC:3.4.17.11]	0.382	0.61	0.532	0.532
crcB, FEX; fluoride exporter	0.382	0.61	0.532	0.532
CS, gltA; citrate synthase [EC:2.3.3.1]	0.382	0.61	0.532	0.532
csh1; CRISPR-associated protein Csh1	0.382	0.61	0.532	0.532
csh2; CRISPR-associated protein Csh2	0.382	0.61	0.532	0.532
csrA; carbon storage regulator	0.382	0.61	0.532	0.532
cutA; periplasmic divalent cation tolerance protein	0.382	0.61	0.532	0.532
cutF, nlpE; copper homeostasis protein (lipoprotein)	0.382	0.61	0.532	0.532
cvpA; membrane protein required for colicin V production	0.382	0.61	0.532	0.532
CYC; cytochrome c	0.382	0.61	0.532	0.532
CYC1, CYT1, petC; ubiquinol-cytochrome c reductase cytochrome c1 subunit	0.382	0.61	0.532	0.532
cydA; cytochrome bd ubiquinol oxidase subunit I [EC:1.10.3.14]	0.382	0.61	0.532	0.532
cydB; cytochrome bd ubiquinol oxidase subunit II [EC:1.10.3.14]	0.382	0.61	0.532	0.532
cynT, can; carbonic anhydrase [EC:4.2.1.1]	0.382	0.61	0.532	0.532
cysE; serine O-acetyltransferase [EC:2.3.1.30]	0.382	0.61	0.532	0.532
cysJ; sulfite reductase (NADPH) flavoprotein alpha-component [EC:1.8.1.2]	0.382	0.61	0.532	0.532
cysK; cysteine synthase A [EC:2.5.1.47]	0.382	0.61	0.532	0.532
cysQ, MET22, BPNT1; 3’(2’), 5’-bisphosphate nucleotidase [EC:3.1.3.7]	0.382	0.61	0.532	0.532
CYTB, petB; ubiquinol-cytochrome c reductase cytochrome b subunit	0.382	0.61	0.532	0.532
czcD, zitB; cobalt-zinc-cadmium efflux system protein	0.382	0.61	0.532	0.532
dadA; D-amino-acid dehydrogenase [EC:1.4.5.1]	0.382	0.61	0.532	0.532
dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]	0.382	0.61	0.532	0.532
dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]	0.382	0.61	0.532	0.532
dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]	0.382	0.61	0.532	0.532
dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]	0.382	0.61	0.532	0.532
dapF; diaminopimelate epimerase [EC:5.1.1.7]	0.382	0.61	0.532	0.532
dat; D-alanine transaminase [EC:2.6.1.21]	0.382	0.61	0.532	0.532
dcd; dCTP deaminase [EC:3.5.4.13]	0.382	0.61	0.532	0.532
dctA; aerobic C4-dicarboxylate transport protein	0.382	0.61	0.532	0.532
dctM; C4-dicarboxylate transporter, DctM subunit	0.382	0.61	0.532	0.532
dctP; C4-dicarboxylate-binding protein DctP	0.382	0.61	0.532	0.532
dctQ; C4-dicarboxylate transporter, DctQ subunit	0.382	0.61	0.532	0.532
dcuA; anaerobic C4-dicarboxylate transporter DcuA	0.382	0.61	0.532	0.532
dcuB; anaerobic C4-dicarboxylate transporter DcuB	0.382	0.61	0.532	0.532
ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]	0.382	0.61	0.532	0.532
dedD; DedD protein	0.382	0.61	0.532	0.532
degP, htrA; serine protease Do [EC:3.4.21.107]	0.382	0.61	0.532	0.532
dgkA, DGK; diacylglycerol kinase (ATP) [EC:2.7.1.107]	0.382	0.61	0.532	0.532
DHODH, pyrD; dihydroorotate dehydrogenase [EC:1.3.5.2]	0.382	0.61	0.532	0.532
dinJ; DNA-damage-inducible protein J	0.382	0.61	0.532	0.532
djlA; DnaJ like chaperone protein	0.382	0.61	0.532	0.532
dksA; DnaK suppressor protein	0.382	0.61	0.532	0.532
dnaA; chromosomal replication initiator protein	0.382	0.61	0.532	0.532
dnaB; replicative DNA helicase [EC:3.6.4.12]	0.382	0.61	0.532	0.532
dnaC; DNA replication protein DnaC	0.382	0.61	0.532	0.532
dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]	0.382	0.61	0.532	0.532
dnaG; DNA primase [EC:2.7.7.-]	0.382	0.61	0.532	0.532
dnaJ; molecular chaperone DnaJ	0.382	0.61	0.532	0.532
dnaK, HSPA9; molecular chaperone DnaK	0.382	0.61	0.532	0.532
dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]	0.382	0.61	0.532	0.532
dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]	0.382	0.61	0.532	0.532
dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]	0.382	0.61	0.532	0.532
DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]	0.382	0.61	0.532	0.532
dpo; DNA polymerase bacteriophage-type [EC:2.7.7.7]	0.382	0.61	0.532	0.532
dps; starvation-inducible DNA-binding protein	0.382	0.61	0.532	0.532
dsbA; thiol:disulfide interchange protein DsbA	0.382	0.61	0.532	0.532
dsbB; disulfide bond formation protein DsbB	0.382	0.61	0.532	0.532
dsbC; thiol:disulfide interchange protein DsbC [EC:5.3.4.1]	0.382	0.61	0.532	0.532
dsbD; thiol:disulfide interchange protein DsbD [EC:1.8.1.8]	0.382	0.61	0.532	0.532
dusB; tRNA-dihydrouridine synthase B [EC:1.-.-.-]	0.382	0.61	0.532	0.532
dxr; 1-deoxy-D-xylulose-5-phosphate reductoisomerase [EC:1.1.1.267]	0.382	0.61	0.532	0.532
dxs; 1-deoxy-D-xylulose-5-phosphate synthase [EC:2.2.1.7]	0.382	0.61	0.532	0.532
E1.1.1.3; homoserine dehydrogenase [EC:1.1.1.3]	0.382	0.61	0.532	0.532
E1.1.1.40, maeB; malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40]	0.382	0.61	0.532	0.532
E1.11.1.5; cytochrome c peroxidase [EC:1.11.1.5]	0.382	0.61	0.532	0.532
E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]	0.382	0.61	0.532	0.532
E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]	0.382	0.61	0.532	0.532
E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]	0.382	0.61	0.532	0.532
E1.6.99.1; NADPH2 dehydrogenase [EC:1.6.99.1]	0.382	0.61	0.532	0.532
E2.1.1.77, pcm; protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77]	0.382	0.61	0.532	0.532
E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]	0.382	0.61	0.532	0.532
E2.2.1.2, talA, talB; transaldolase [EC:2.2.1.2]	0.382	0.61	0.532	0.532
E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]	0.382	0.61	0.532	0.532
E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6]	0.382	0.61	0.532	0.532
E2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]	0.382	0.61	0.532	0.532
E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]	0.382	0.61	0.532	0.532
E2.7.1.71, aroK, aroL; shikimate kinase [EC:2.7.1.71]	0.382	0.61	0.532	0.532
E2.7.4.8, gmk; guanylate kinase [EC:2.7.4.8]	0.382	0.61	0.532	0.532
E2.7.7.3A, coaD, kdtB; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]	0.382	0.61	0.532	0.532
E2.7.7.41, CDS1, CDS2, cdsA; phosphatidate cytidylyltransferase [EC:2.7.7.41]	0.382	0.61	0.532	0.532
E3.1.11.2, xthA; exodeoxyribonuclease III [EC:3.1.11.2]	0.382	0.61	0.532	0.532
E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]	0.382	0.61	0.532	0.532
E3.4.21.102, prc, ctpA; carboxyl-terminal processing protease [EC:3.4.21.102]	0.382	0.61	0.532	0.532
E3.5.1.1, ansA, ansB; L-asparaginase [EC:3.5.1.1]	0.382	0.61	0.532	0.532
E3.5.5.1; nitrilase [EC:3.5.5.1]	0.382	0.61	0.532	0.532
E3.5.99.7; 1-aminocyclopropane-1-carboxylate deaminase [EC:3.5.99.7]	0.382	0.61	0.532	0.532
E4.1.1.49, pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]	0.382	0.61	0.532	0.532
E4.2.1.2AA, fumA; fumarate hydratase subunit alpha [EC:4.2.1.2]	0.382	0.61	0.532	0.532
E4.2.1.2AB, fumB; fumarate hydratase subunit beta [EC:4.2.1.2]	0.382	0.61	0.532	0.532
E4.2.1.2B, fumC, FH; fumarate hydratase, class II [EC:4.2.1.2]	0.382	0.61	0.532	0.532
E4.3.1.19, ilvA, tdcB; threonine dehydratase [EC:4.3.1.19]	0.382	0.61	0.532	0.532
E5.1.3.6; UDP-glucuronate 4-epimerase [EC:5.1.3.6]	0.382	0.61	0.532	0.532
E5.2.1.8; peptidylprolyl isomerase [EC:5.2.1.8]	0.382	0.61	0.532	0.532
E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]	0.382	0.61	0.532	0.532
EARS, gltX; glutamyl-tRNA synthetase [EC:6.1.1.17]	0.382	0.61	0.532	0.532
eco; ecotin	0.382	0.61	0.532	0.532
efp; elongation factor P	0.382	0.61	0.532	0.532
engA, der; GTPase	0.382	0.61	0.532	0.532
engB; GTP-binding protein	0.382	0.61	0.532	0.532
ENO, eno; enolase [EC:4.2.1.11]	0.382	0.61	0.532	0.532
eptA, pmrC; lipid A ethanolaminephosphotransferase [EC:2.7.8.43]	0.382	0.61	0.532	0.532
era, ERAL1; GTPase	0.382	0.61	0.532	0.532
exbB; biopolymer transport protein ExbB	0.382	0.61	0.532	0.532
exbD; biopolymer transport protein ExbD	0.382	0.61	0.532	0.532
fabB; 3-oxoacyl-[acyl-carrier-protein] synthase I [EC:2.3.1.41]	0.382	0.61	0.532	0.532
fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]	0.382	0.61	0.532	0.532
fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]	0.382	0.61	0.532	0.532
fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]	0.382	0.61	0.532	0.532
fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]	0.382	0.61	0.532	0.532
fabI; enoyl-[acyl-carrier protein] reductase I [EC:1.3.1.9 1.3.1.10]	0.382	0.61	0.532	0.532
fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]	0.382	0.61	0.532	0.532
fadL; long-chain fatty acid transport protein	0.382	0.61	0.532	0.532
FAEB; feruloyl esterase [EC:3.1.1.73]	0.382	0.61	0.532	0.532
FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]	0.382	0.61	0.532	0.532
FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]	0.382	0.61	0.532	0.532
FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]	0.382	0.61	0.532	0.532
FBP, fbp; fructose-1,6-bisphosphatase I [EC:3.1.3.11]	0.382	0.61	0.532	0.532
fdhA; formate dehydrogenase (NADP+) alpha subunit [EC:1.17.1.10]	0.382	0.61	0.532	0.532
fdhD; FdhD protein	0.382	0.61	0.532	0.532
fdoG, fdhF, fdwA; formate dehydrogenase major subunit [EC:1.17.1.9]	0.382	0.61	0.532	0.532
fdoH, fdsB; formate dehydrogenase iron-sulfur subunit	0.382	0.61	0.532	0.532
fdoI, fdsG; formate dehydrogenase subunit gamma	0.382	0.61	0.532	0.532
fhaB; filamentous hemagglutinin	0.382	0.61	0.532	0.532
fhs; formate–tetrahydrofolate ligase [EC:6.3.4.3]	0.382	0.61	0.532	0.532
fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase FkpA [EC:5.2.1.8]	0.382	0.61	0.532	0.532
flaG; flagellar protein FlaG	0.382	0.61	0.532	0.532
fldA, nifF, isiB; flavodoxin I	0.382	0.61	0.532	0.532
flgA; flagella basal body P-ring formation protein FlgA	0.382	0.61	0.532	0.532
flgB; flagellar basal-body rod protein FlgB	0.382	0.61	0.532	0.532
flgC; flagellar basal-body rod protein FlgC	0.382	0.61	0.532	0.532
flgD; flagellar basal-body rod modification protein FlgD	0.382	0.61	0.532	0.532
flgE; flagellar hook protein FlgE	0.382	0.61	0.532	0.532
flgG; flagellar basal-body rod protein FlgG	0.382	0.61	0.532	0.532
flgH; flagellar L-ring protein precursor FlgH	0.382	0.61	0.532	0.532
flgI; flagellar P-ring protein precursor FlgI	0.382	0.61	0.532	0.532
flgK; flagellar hook-associated protein 1 FlgK	0.382	0.61	0.532	0.532
flgL; flagellar hook-associated protein 3 FlgL	0.382	0.61	0.532	0.532
flhA; flagellar biosynthesis protein FlhA	0.382	0.61	0.532	0.532
flhB; flagellar biosynthetic protein FlhB	0.382	0.61	0.532	0.532
flhB2; flagellar biosynthesis protein	0.382	0.61	0.532	0.532
flhF; flagellar biosynthesis protein FlhF	0.382	0.61	0.532	0.532
flhG, fleN; flagellar biosynthesis protein FlhG	0.382	0.61	0.532	0.532
fliA; RNA polymerase sigma factor for flagellar operon FliA	0.382	0.61	0.532	0.532
fliC; flagellin	0.382	0.61	0.532	0.532
fliD; flagellar hook-associated protein 2	0.382	0.61	0.532	0.532
fliE; flagellar hook-basal body complex protein FliE	0.382	0.61	0.532	0.532
fliF; flagellar M-ring protein FliF	0.382	0.61	0.532	0.532
fliG; flagellar motor switch protein FliG	0.382	0.61	0.532	0.532
fliH; flagellar assembly protein FliH	0.382	0.61	0.532	0.532
fliI; flagellum-specific ATP synthase [EC:3.6.3.14]	0.382	0.61	0.532	0.532
fliL; flagellar FliL protein	0.382	0.61	0.532	0.532
fliM; flagellar motor switch protein FliM	0.382	0.61	0.532	0.532
fliNY, fliN; flagellar motor switch protein FliN/FliY	0.382	0.61	0.532	0.532
fliP; flagellar biosynthetic protein FliP	0.382	0.61	0.532	0.532
fliQ; flagellar biosynthetic protein FliQ	0.382	0.61	0.532	0.532
fliR; flagellar biosynthetic protein FliR	0.382	0.61	0.532	0.532
fliS; flagellar protein FliS	0.382	0.61	0.532	0.532
fliW; flagellar assembly factor FliW	0.382	0.61	0.532	0.532
fliY; cystine transport system substrate-binding protein	0.382	0.61	0.532	0.532
fnr; CRP/FNR family transcriptional regulator, anaerobic regulatory protein	0.382	0.61	0.532	0.532
folB; 7,8-dihydroneopterin aldolase/epimerase/oxygenase [EC:4.1.2.25 5.1.99.8 1.13.11.81]	0.382	0.61	0.532	0.532
folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]	0.382	0.61	0.532	0.532
folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]	0.382	0.61	0.532	0.532
folK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:2.7.6.3]	0.382	0.61	0.532	0.532
folP; dihydropteroate synthase [EC:2.5.1.15]	0.382	0.61	0.532	0.532
frdA; fumarate reductase flavoprotein subunit [EC:1.3.5.4]	0.382	0.61	0.532	0.532
frdB; fumarate reductase iron-sulfur subunit [EC:1.3.5.4]	0.382	0.61	0.532	0.532
frdC; fumarate reductase subunit C	0.382	0.61	0.532	0.532
frr, MRRF, RRF; ribosome recycling factor	0.382	0.61	0.532	0.532
fsr; MFS transporter, FSR family, fosmidomycin resistance protein	0.382	0.61	0.532	0.532
FTR, FTH1, efeU; high-affinity iron transporter	0.382	0.61	0.532	0.532
ftsA; cell division protein FtsA	0.382	0.61	0.532	0.532
ftsE; cell division transport system ATP-binding protein	0.382	0.61	0.532	0.532
ftsH, hflB; cell division protease FtsH [EC:3.4.24.-]	0.382	0.61	0.532	0.532
ftsI; cell division protein FtsI (penicillin-binding protein 3) [EC:3.4.16.4]	0.382	0.61	0.532	0.532
ftsK, spoIIIE; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family	0.382	0.61	0.532	0.532
ftsW, spoVE; cell division protein FtsW	0.382	0.61	0.532	0.532
ftsX; cell division transport system permease protein	0.382	0.61	0.532	0.532
ftsY; fused signal recognition particle receptor	0.382	0.61	0.532	0.532
ftsZ; cell division protein FtsZ	0.382	0.61	0.532	0.532
fucA; L-fuculose-phosphate aldolase [EC:4.1.2.17]	0.382	0.61	0.532	0.532
fur, zur, furB; Fur family transcriptional regulator, ferric uptake regulator	0.382	0.61	0.532	0.532
fusA, GFM, EFG; elongation factor G	0.382	0.61	0.532	0.532
fxsA; UPF0716 protein FxsA	0.382	0.61	0.532	0.532
galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2]	0.382	0.61	0.532	0.532
GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]	0.382	0.61	0.532	0.532
gatA, QRSL1; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]	0.382	0.61	0.532	0.532
gatB, PET112; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]	0.382	0.61	0.532	0.532
gatC, GATC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]	0.382	0.61	0.532	0.532
GCH1, folE; GTP cyclohydrolase IA [EC:3.5.4.16]	0.382	0.61	0.532	0.532
gcpE, ispG; (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [EC:1.17.7.1 1.17.7.3]	0.382	0.61	0.532	0.532
gidA, mnmG, MTO1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme	0.382	0.61	0.532	0.532
gidB, rsmG; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]	0.382	0.61	0.532	0.532
glmM; phosphoglucosamine mutase [EC:5.4.2.10]	0.382	0.61	0.532	0.532
glmS, GFPT; glucosamine—fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]	0.382	0.61	0.532	0.532
glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]	0.382	0.61	0.532	0.532
glnA, GLUL; glutamine synthetase [EC:6.3.1.2]	0.382	0.61	0.532	0.532
glnD; [protein-PII] uridylyltransferase [EC:2.7.7.59]	0.382	0.61	0.532	0.532
GLUD1_2, gdhA; glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3]	0.382	0.61	0.532	0.532
gluQ; glutamyl-Q tRNA(Asp) synthetase [EC:6.1.1.-]	0.382	0.61	0.532	0.532
glxK, garK; glycerate 2-kinase [EC:2.7.1.165]	0.382	0.61	0.532	0.532
glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]	0.382	0.61	0.532	0.532
glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]	0.382	0.61	0.532	0.532
glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]	0.382	0.61	0.532	0.532
gmhA, lpcA; D-sedoheptulose 7-phosphate isomerase [EC:5.3.1.28]	0.382	0.61	0.532	0.532
gmhB; D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [EC:3.1.3.82 3.1.3.83]	0.382	0.61	0.532	0.532
gmhC, hldE, waaE, rfaE; D-beta-D-heptose 7-phosphate kinase / D-beta-D-heptose 1-phosphate adenosyltransferase [EC:2.7.1.167 2.7.7.70]	0.382	0.61	0.532	0.532
gmhD, rfaD; ADP-L-glycero-D-manno-heptose 6-epimerase [EC:5.1.3.20]	0.382	0.61	0.532	0.532
gph; phosphoglycolate phosphatase [EC:3.1.3.18]	0.382	0.61	0.532	0.532
GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]	0.382	0.61	0.532	0.532
gpmI; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [EC:5.4.2.12]	0.382	0.61	0.532	0.532
gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]	0.382	0.61	0.532	0.532
gpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]	0.382	0.61	0.532	0.532
greA; transcription elongation factor GreA	0.382	0.61	0.532	0.532
groEL, HSPD1; chaperonin GroEL	0.382	0.61	0.532	0.532
groES, HSPE1; chaperonin GroES	0.382	0.61	0.532	0.532
GRPE; molecular chaperone GrpE	0.382	0.61	0.532	0.532
gspD; general secretion pathway protein D	0.382	0.61	0.532	0.532
gspE; general secretion pathway protein E	0.382	0.61	0.532	0.532
gspF; general secretion pathway protein F	0.382	0.61	0.532	0.532
gspG; general secretion pathway protein G	0.382	0.61	0.532	0.532
guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]	0.382	0.61	0.532	0.532
gyrA; DNA gyrase subunit A [EC:5.99.1.3]	0.382	0.61	0.532	0.532
gyrB; DNA gyrase subunit B [EC:5.99.1.3]	0.382	0.61	0.532	0.532
HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]	0.382	0.61	0.532	0.532
hcp; hydroxylamine reductase [EC:1.7.99.1]	0.382	0.61	0.532	0.532
hcp; type VI secretion system secreted protein Hcp	0.382	0.61	0.532	0.532
hdhA; 7-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.159]	0.382	0.61	0.532	0.532
hemA; glutamyl-tRNA reductase [EC:1.2.1.70]	0.382	0.61	0.532	0.532
hemB, ALAD; porphobilinogen synthase [EC:4.2.1.24]	0.382	0.61	0.532	0.532
hemC, HMBS; hydroxymethylbilane synthase [EC:2.5.1.61]	0.382	0.61	0.532	0.532
hemD, UROS; uroporphyrinogen-III synthase [EC:4.2.1.75]	0.382	0.61	0.532	0.532
hemE, UROD; uroporphyrinogen decarboxylase [EC:4.1.1.37]	0.382	0.61	0.532	0.532
hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.99.1.1 4.99.1.9]	0.382	0.61	0.532	0.532
hemK, prmC, HEMK; release factor glutamine methyltransferase [EC:2.1.1.297]	0.382	0.61	0.532	0.532
hemL; glutamate-1-semialdehyde 2,1-aminomutase [EC:5.4.3.8]	0.382	0.61	0.532	0.532
hemN, hemZ; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]	0.382	0.61	0.532	0.532
HINT1, hinT, hit; histidine triad (HIT) family protein	0.382	0.61	0.532	0.532
hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]	0.382	0.61	0.532	0.532
hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]	0.382	0.61	0.532	0.532
hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]	0.382	0.61	0.532	0.532
hisD; histidinol dehydrogenase [EC:1.1.1.23]	0.382	0.61	0.532	0.532
hisF; cyclase [EC:4.1.3.-]	0.382	0.61	0.532	0.532
hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]	0.382	0.61	0.532	0.532
hisH; glutamine amidotransferase [EC:2.4.2.-]	0.382	0.61	0.532	0.532
hisIE; phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase [EC:3.6.1.31 3.5.4.19]	0.382	0.61	0.532	0.532
holA; DNA polymerase III subunit delta [EC:2.7.7.7]	0.382	0.61	0.532	0.532
holB; DNA polymerase III subunit delta’ [EC:2.7.7.7]	0.382	0.61	0.532	0.532
hprA; glycerate dehydrogenase [EC:1.1.1.29]	0.382	0.61	0.532	0.532
hrcA; heat-inducible transcriptional repressor	0.382	0.61	0.532	0.532
hsdM; type I restriction enzyme M protein [EC:2.1.1.72]	0.382	0.61	0.532	0.532
hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]	0.382	0.61	0.532	0.532
hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]	0.382	0.61	0.532	0.532
hslU; ATP-dependent HslUV protease ATP-binding subunit HslU	0.382	0.61	0.532	0.532
hslV, clpQ; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]	0.382	0.61	0.532	0.532
HSP90A, htpG; molecular chaperone HtpG	0.382	0.61	0.532	0.532
hspR; MerR family transcriptional regulator, heat shock protein HspR	0.382	0.61	0.532	0.532
htpX; heat shock protein HtpX [EC:3.4.24.-]	0.382	0.61	0.532	0.532
hupB; DNA-binding protein HU-beta	0.382	0.61	0.532	0.532
hyaC; Ni/Fe-hydrogenase 1 B-type cytochrome subunit	0.382	0.61	0.532	0.532
hyaD, hybD; hydrogenase maturation protease [EC:3.4.23.-]	0.382	0.61	0.532	0.532
hycH; formate hydrogenlyase maturation protein HycH	0.382	0.61	0.532	0.532
hycI; hydrogenase 3 maturation protease [EC:3.4.23.51]	0.382	0.61	0.532	0.532
hydA; quinone-reactive Ni/Fe-hydrogenase small subunit [EC:1.12.5.1]	0.382	0.61	0.532	0.532
hydB; quinone-reactive Ni/Fe-hydrogenase large subunit [EC:1.12.5.1]	0.382	0.61	0.532	0.532
hyfA; hydrogenase-4 component A [EC:1.-.-.-]	0.382	0.61	0.532	0.532
hyfB; hydrogenase-4 component B [EC:1.-.-.-]	0.382	0.61	0.532	0.532
hyfC; hydrogenase-4 component C [EC:1.-.-.-]	0.382	0.61	0.532	0.532
hyfE; hydrogenase-4 component E [EC:1.-.-.-]	0.382	0.61	0.532	0.532
hyfF; hydrogenase-4 component F [EC:1.-.-.-]	0.382	0.61	0.532	0.532
hypA, hybF; hydrogenase nickel incorporation protein HypA/HybF	0.382	0.61	0.532	0.532
hypB; hydrogenase nickel incorporation protein HypB	0.382	0.61	0.532	0.532
hypC; hydrogenase expression/formation protein HypC	0.382	0.61	0.532	0.532
hypD; hydrogenase expression/formation protein HypD	0.382	0.61	0.532	0.532
hypE; hydrogenase expression/formation protein HypE	0.382	0.61	0.532	0.532
hypF; hydrogenase maturation protein HypF	0.382	0.61	0.532	0.532
iadA; beta-aspartyl-dipeptidase (metallo-type) [EC:3.4.19.-]	0.382	0.61	0.532	0.532
IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]	0.382	0.61	0.532	0.532
IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]	0.382	0.61	0.532	0.532
ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]	0.382	0.61	0.532	0.532
ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]	0.382	0.61	0.532	0.532
impB; type VI secretion system protein ImpB	0.382	0.61	0.532	0.532
impC; type VI secretion system protein ImpC	0.382	0.61	0.532	0.532
IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205]	0.382	0.61	0.532	0.532
impG, vasA; type VI secretion system protein ImpG	0.382	0.61	0.532	0.532
impH, vasB; type VI secretion system protein ImpH	0.382	0.61	0.532	0.532
impJ, vasE; type VI secretion system protein ImpJ	0.382	0.61	0.532	0.532
impK, ompA, vasF, dotU; type VI secretion system protein ImpK	0.382	0.61	0.532	0.532
infA; translation initiation factor IF-1	0.382	0.61	0.532	0.532
infB, MTIF2; translation initiation factor IF-2	0.382	0.61	0.532	0.532
infC, MTIF3; translation initiation factor IF-3	0.382	0.61	0.532	0.532
int; integrase	0.382	0.61	0.532	0.532
iscS, NFS1; cysteine desulfurase [EC:2.8.1.7]	0.382	0.61	0.532	0.532
ispA; farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10]	0.382	0.61	0.532	0.532
ispB; octaprenyl-diphosphate synthase [EC:2.5.1.90]	0.382	0.61	0.532	0.532
ispDF; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase / 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [EC:2.7.7.60 4.6.1.12]	0.382	0.61	0.532	0.532
ispE; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [EC:2.7.1.148]	0.382	0.61	0.532	0.532
ispH, lytB; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase [EC:1.17.7.4]	0.382	0.61	0.532	0.532
jag; spoIIIJ-associated protein	0.382	0.61	0.532	0.532
K02481; two-component system, NtrC family, response regulator	0.382	0.61	0.532	0.532
K02482; two-component system, NtrC family, sensor kinase [EC:2.7.13.3]	0.382	0.61	0.532	0.532
K02483; two-component system, OmpR family, response regulator	0.382	0.61	0.532	0.532
K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]	0.382	0.61	0.532	0.532
K06867; uncharacterized protein	0.382	0.61	0.532	0.532
K06872; uncharacterized protein	0.382	0.61	0.532	0.532
K06882; uncharacterized protein	0.382	0.61	0.532	0.532
K06894; uncharacterized protein	0.382	0.61	0.532	0.532
K06921; uncharacterized protein	0.382	0.61	0.532	0.532
K06923; uncharacterized protein	0.382	0.61	0.532	0.532
K06940; uncharacterized protein	0.382	0.61	0.532	0.532
K06950; uncharacterized protein	0.382	0.61	0.532	0.532
K06960; uncharacterized protein	0.382	0.61	0.532	0.532
K07003; uncharacterized protein	0.382	0.61	0.532	0.532
K07005; uncharacterized protein	0.382	0.61	0.532	0.532
K07007; uncharacterized protein	0.382	0.61	0.532	0.532
K07017; uncharacterized protein	0.382	0.61	0.532	0.532
K07023; putative hydrolases of HD superfamily	0.382	0.61	0.532	0.532
K07043; uncharacterized protein	0.382	0.61	0.532	0.532
K07058; membrane protein	0.382	0.61	0.532	0.532
K07080; uncharacterized protein	0.382	0.61	0.532	0.532
K07082; UPF0755 protein	0.382	0.61	0.532	0.532
K07088; uncharacterized protein	0.382	0.61	0.532	0.532
K07090; uncharacterized protein	0.382	0.61	0.532	0.532
K07097; uncharacterized protein	0.382	0.61	0.532	0.532
K07098; uncharacterized protein	0.382	0.61	0.532	0.532
K07100; putative phosphoribosyl transferase	0.382	0.61	0.532	0.532
K07112; uncharacterized protein	0.382	0.61	0.532	0.532
K07118; uncharacterized protein	0.382	0.61	0.532	0.532
K07124; uncharacterized protein	0.382	0.61	0.532	0.532
K07126; uncharacterized protein	0.382	0.61	0.532	0.532
K07133; uncharacterized protein	0.382	0.61	0.532	0.532
K07164; uncharacterized protein	0.382	0.61	0.532	0.532
K07166; ACT domain-containing protein	0.382	0.61	0.532	0.532
K07223; putative iron-dependent peroxidase	0.382	0.61	0.532	0.532
K07270; glycosyl transferase, family 25	0.382	0.61	0.532	0.532
K07318; adenine-specific DNA-methyltransferase [EC:2.1.1.72]	0.382	0.61	0.532	0.532
K07457; endonuclease III related protein	0.382	0.61	0.532	0.532
K07501; 3’-5’ exonuclease	0.382	0.61	0.532	0.532
K08303; putative protease [EC:3.4.-.-]	0.382	0.61	0.532	0.532
K08973; putative membrane protein	0.382	0.61	0.532	0.532
K09117; uncharacterized protein	0.382	0.61	0.532	0.532
K09157; uncharacterized protein	0.382	0.61	0.532	0.532
K09747; uncharacterized protein	0.382	0.61	0.532	0.532
K09778; uncharacterized protein	0.382	0.61	0.532	0.532
K09792; uncharacterized protein	0.382	0.61	0.532	0.532
K09794; uncharacterized protein	0.382	0.61	0.532	0.532
K09798; uncharacterized protein	0.382	0.61	0.532	0.532
K09804; uncharacterized protein	0.382	0.61	0.532	0.532
K09860; uncharacterized protein	0.382	0.61	0.532	0.532
K09861; uncharacterized protein	0.382	0.61	0.532	0.532
K09925; uncharacterized protein	0.382	0.61	0.532	0.532
K09935; uncharacterized protein	0.382	0.61	0.532	0.532
K09943; uncharacterized protein	0.382	0.61	0.532	0.532
K09944; uncharacterized protein	0.382	0.61	0.532	0.532
K09974; uncharacterized protein	0.382	0.61	0.532	0.532
K09979; uncharacterized protein	0.382	0.61	0.532	0.532
K11905; type VI secretion system protein	0.382	0.61	0.532	0.532
K13819; NifU-like protein	0.382	0.61	0.532	0.532
K15977; putative oxidoreductase	0.382	0.61	0.532	0.532
K18284; adenosylhomocysteine/aminodeoxyfutalosine nucleosidase [EC:3.2.2.9 3.2.2.30]	0.382	0.61	0.532	0.532
KAE1, tsaD, QRI7; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]	0.382	0.61	0.532	0.532
KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]	0.382	0.61	0.532	0.532
kch, trkA, mthK, pch; voltage-gated potassium channel	0.382	0.61	0.532	0.532
kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) [EC:2.5.1.55]	0.382	0.61	0.532	0.532
kdsB; 3-deoxy-manno-octulosonate cytidylyltransferase (CMP-KDO synthetase) [EC:2.7.7.38]	0.382	0.61	0.532	0.532
kdsC; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) [EC:3.1.3.45]	0.382	0.61	0.532	0.532
kdsD, kpsF; arabinose-5-phosphate isomerase [EC:5.3.1.13]	0.382	0.61	0.532	0.532
kdtA, waaA; 3-deoxy-D-manno-octulosonic-acid transferase [EC:2.4.99.12 2.4.99.13 2.4.99.14 2.4.99.15]	0.382	0.61	0.532	0.532
korA, oorA, oforA; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit alpha [EC:1.2.7.3 1.2.7.11]	0.382	0.61	0.532	0.532
korB, oorB, oforB; 2-oxoglutarate/2-oxoacid ferredoxin oxidoreductase subunit beta [EC:1.2.7.3 1.2.7.11]	0.382	0.61	0.532	0.532
korC, oorC; 2-oxoglutarate ferredoxin oxidoreductase subunit gamma [EC:1.2.7.3]	0.382	0.61	0.532	0.532
korD, oorD; 2-oxoglutarate ferredoxin oxidoreductase subunit delta [EC:1.2.7.3]	0.382	0.61	0.532	0.532
ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]	0.382	0.61	0.532	0.532
lapB; ATP-binding cassette, subfamily C, bacterial LapB	0.382	0.61	0.532	0.532
lapC; membrane fusion protein, adhesin transport system	0.382	0.61	0.532	0.532
lapE; outer membrane protein, adhesin transport system	0.382	0.61	0.532	0.532
larB; pyridinium-3,5-biscarboxylic acid mononucleotide synthase [EC:2.5.1.143]	0.382	0.61	0.532	0.532
larC; pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel chelatase [EC:4.99.1.12]	0.382	0.61	0.532	0.532
larE; pyridinium-3,5-biscarboxylic acid mononucleotide sulfurtransferase	0.382	0.61	0.532	0.532
LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]	0.382	0.61	0.532	0.532
legF, ptmB; CMP-N,N’-diacetyllegionaminic acid synthase [EC:2.7.7.82]	0.382	0.61	0.532	0.532
legG, neuC2; GDP/UDP-N,N’-diacetylbacillosamine 2-epimerase (hydrolysing) [EC:3.2.1.184]	0.382	0.61	0.532	0.532
legI, neuB2; N,N’-diacetyllegionaminate synthase [EC:2.5.1.101]	0.382	0.61	0.532	0.532
lemA; LemA protein	0.382	0.61	0.532	0.532
lepA; GTP-binding protein LepA	0.382	0.61	0.532	0.532
lepB; signal peptidase I [EC:3.4.21.89]	0.382	0.61	0.532	0.532
leuA, IMS; 2-isopropylmalate synthase [EC:2.3.3.13]	0.382	0.61	0.532	0.532
leuB, IMDH; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]	0.382	0.61	0.532	0.532
leuC, IPMI-L; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]	0.382	0.61	0.532	0.532
leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]	0.382	0.61	0.532	0.532
lgt, umpA; phosphatidylglycerol:prolipoprotein diacylglycerol transferase [EC:2.-.-.-]	0.382	0.61	0.532	0.532
LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]	0.382	0.61	0.532	0.532
linN; cholesterol transport system auxiliary component	0.382	0.61	0.532	0.532
lnt; apolipoprotein N-acyltransferase [EC:2.3.1.-]	0.382	0.61	0.532	0.532
lolA; outer membrane lipoprotein carrier protein	0.382	0.61	0.532	0.532
lon; ATP-dependent Lon protease [EC:3.4.21.53]	0.382	0.61	0.532	0.532
lptA; lipopolysaccharide export system protein LptA	0.382	0.61	0.532	0.532
lptB; lipopolysaccharide export system ATP-binding protein [EC:3.6.3.-]	0.382	0.61	0.532	0.532
lptD, imp, ostA; LPS-assembly protein	0.382	0.61	0.532	0.532
lptF; lipopolysaccharide export system permease protein	0.382	0.61	0.532	0.532
lptG; lipopolysaccharide export system permease protein	0.382	0.61	0.532	0.532
lpxA; UDP-N-acetylglucosamine acyltransferase [EC:2.3.1.129]	0.382	0.61	0.532	0.532
lpxB; lipid-A-disaccharide synthase [EC:2.4.1.182]	0.382	0.61	0.532	0.532
lpxC; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase [EC:3.5.1.108]	0.382	0.61	0.532	0.532
lpxD; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase [EC:2.3.1.191]	0.382	0.61	0.532	0.532
lpxH; UDP-2,3-diacylglucosamine hydrolase [EC:3.6.1.54]	0.382	0.61	0.532	0.532
lpxK; tetraacyldisaccharide 4’-kinase [EC:2.7.1.130]	0.382	0.61	0.532	0.532
lpxL, htrB; Kdo2-lipid IVA lauroyltransferase [EC:2.3.1.241]	0.382	0.61	0.532	0.532
lspA; signal peptidase II [EC:3.4.23.36]	0.382	0.61	0.532	0.532
luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]	0.382	0.61	0.532	0.532
LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7]	0.382	0.61	0.532	0.532
LYS5, acpT; 4’-phosphopantetheinyl transferase [EC:2.7.8.-]	0.382	0.61	0.532	0.532
lysA; diaminopimelate decarboxylase [EC:4.1.1.20]	0.382	0.61	0.532	0.532
lysC; aspartate kinase [EC:2.7.2.4]	0.382	0.61	0.532	0.532
lysE, argO; L-lysine exporter family protein LysE/ArgO	0.382	0.61	0.532	0.532
macA; membrane fusion protein, macrolide-specific efflux system	0.382	0.61	0.532	0.532
macB; macrolide transport system ATP-binding/permease protein [EC:3.6.3.-]	0.382	0.61	0.532	0.532
maf; septum formation protein	0.382	0.61	0.532	0.532
map; methionyl aminopeptidase [EC:3.4.11.18]	0.382	0.61	0.532	0.532
MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]	0.382	0.61	0.532	0.532
mcp; methyl-accepting chemotaxis protein	0.382	0.61	0.532	0.532
mcrB; 5-methylcytosine-specific restriction enzyme B [EC:3.1.21.-]	0.382	0.61	0.532	0.532
mcrC; 5-methylcytosine-specific restriction enzyme subunit McrC	0.382	0.61	0.532	0.532
mdaB; modulator of drug activity B	0.382	0.61	0.532	0.532
mdh; malate dehydrogenase [EC:1.1.1.37]	0.382	0.61	0.532	0.532
merP; periplasmic mercuric ion binding protein	0.382	0.61	0.532	0.532
merT; mercuric ion transport protein	0.382	0.61	0.532	0.532
metC; cystathionine beta-lyase [EC:4.4.1.8]	0.382	0.61	0.532	0.532
metE; 5-methyltetrahydropteroyltriglutamate–homocysteine methyltransferase [EC:2.1.1.14]	0.382	0.61	0.532	0.532
metI; D-methionine transport system permease protein	0.382	0.61	0.532	0.532
metK; S-adenosylmethionine synthetase [EC:2.5.1.6]	0.382	0.61	0.532	0.532
metN; D-methionine transport system ATP-binding protein	0.382	0.61	0.532	0.532
metQ; D-methionine transport system substrate-binding protein	0.382	0.61	0.532	0.532
metX; homoserine O-acetyltransferase/O-succinyltransferase [EC:2.3.1.31 2.3.1.46]	0.382	0.61	0.532	0.532
metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]	0.382	0.61	0.532	0.532
mfd; transcription-repair coupling factor (superfamily II helicase) [EC:3.6.4.-]	0.382	0.61	0.532	0.532
mgtE; magnesium transporter	0.382	0.61	0.532	0.532
miaA, TRIT1; tRNA dimethylallyltransferase [EC:2.5.1.75]	0.382	0.61	0.532	0.532
miaB; tRNA-2-methylthio-N6-dimethylallyladenosine synthase [EC:2.8.4.3]	0.382	0.61	0.532	0.532
mlaA, vacJ; phospholipid-binding lipoprotein MlaA	0.382	0.61	0.532	0.532
mlaC; phospholipid transport system substrate-binding protein	0.382	0.61	0.532	0.532
mlaD, linM; phospholipid/cholesterol/gamma-HCH transport system substrate-binding protein	0.382	0.61	0.532	0.532
mlaE, linK; phospholipid/cholesterol/gamma-HCH transport system permease protein	0.382	0.61	0.532	0.532
mlaF, linL, mkl; phospholipid/cholesterol/gamma-HCH transport system ATP-binding protein	0.382	0.61	0.532	0.532
mltD, dniR; membrane-bound lytic murein transglycosylase D [EC:4.2.2.-]	0.382	0.61	0.532	0.532
mnmA, trmU; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]	0.382	0.61	0.532	0.532
mnmC; tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein [EC:2.1.1.61 1.5.-.-]	0.382	0.61	0.532	0.532
mnmE, trmE, MSS1; tRNA modification GTPase [EC:3.6.-.-]	0.382	0.61	0.532	0.532
moaA, CNX2; GTP 3’,8-cyclase [EC:4.1.99.22]	0.382	0.61	0.532	0.532
moaC, CNX3; cyclic pyranopterin monophosphate synthase [EC:4.6.1.17]	0.382	0.61	0.532	0.532
moaD, cysO; sulfur-carrier protein	0.382	0.61	0.532	0.532
mobA; molybdenum cofactor guanylyltransferase [EC:2.7.7.77]	0.382	0.61	0.532	0.532
mobB; molybdopterin-guanine dinucleotide biosynthesis adapter protein	0.382	0.61	0.532	0.532
MOCS2B, moaE; molybdopterin synthase catalytic subunit [EC:2.8.1.12]	0.382	0.61	0.532	0.532
modA; molybdate transport system substrate-binding protein	0.382	0.61	0.532	0.532
modB; molybdate transport system permease protein	0.382	0.61	0.532	0.532
modC; molybdate transport system ATP-binding protein [EC:3.6.3.29]	0.382	0.61	0.532	0.532
modD; molybdenum transport protein [EC:2.4.2.-]	0.382	0.61	0.532	0.532
modE; molybdate transport system regulatory protein	0.382	0.61	0.532	0.532
moeA; molybdopterin molybdotransferase [EC:2.10.1.1]	0.382	0.61	0.532	0.532
mogA; molybdopterin adenylyltransferase [EC:2.7.7.75]	0.382	0.61	0.532	0.532
motA; chemotaxis protein MotA	0.382	0.61	0.532	0.532
motB; chemotaxis protein MotB	0.382	0.61	0.532	0.532
mqnA; chorismate dehydratase [EC:4.2.1.151]	0.382	0.61	0.532	0.532
mqnC; cyclic dehypoxanthinyl futalosine synthase [EC:1.21.98.1]	0.382	0.61	0.532	0.532
mqnD; 1,4-dihydroxy-6-naphthoate synthase [EC:1.14.-.-]	0.382	0.61	0.532	0.532
mqnE; aminodeoxyfutalosine synthase [EC:2.5.1.120]	0.382	0.61	0.532	0.532
mqo; malate dehydrogenase (quinone) [EC:1.1.5.4]	0.382	0.61	0.532	0.532
mraW, rsmH; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]	0.382	0.61	0.532	0.532
mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]	0.382	0.61	0.532	0.532
mrcA; penicillin-binding protein 1A [EC:2.4.1.129 3.4.16.4]	0.382	0.61	0.532	0.532
mrdA; penicillin-binding protein 2 [EC:3.4.16.4]	0.382	0.61	0.532	0.532
mreB; rod shape-determining protein MreB and related proteins	0.382	0.61	0.532	0.532
mreC; rod shape-determining protein MreC	0.382	0.61	0.532	0.532
mrp, NUBPL; ATP-binding protein involved in chromosome partitioning	0.382	0.61	0.532	0.532
mrr; restriction system protein	0.382	0.61	0.532	0.532
msbA; ATP-binding cassette, subfamily B, bacterial MsbA [EC:3.6.3.-]	0.382	0.61	0.532	0.532
mscL; large conductance mechanosensitive channel	0.382	0.61	0.532	0.532
msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]	0.382	0.61	0.532	0.532
MTFMT, fmt; methionyl-tRNA formyltransferase [EC:2.1.2.9]	0.382	0.61	0.532	0.532
MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]	0.382	0.61	0.532	0.532
murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]	0.382	0.61	0.532	0.532
murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]	0.382	0.61	0.532	0.532
murC; UDP-N-acetylmuramate–alanine ligase [EC:6.3.2.8]	0.382	0.61	0.532	0.532
murD; UDP-N-acetylmuramoylalanine–D-glutamate ligase [EC:6.3.2.9]	0.382	0.61	0.532	0.532
murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase [EC:6.3.2.13]	0.382	0.61	0.532	0.532
murF; UDP-N-acetylmuramoyl-tripeptide–D-alanyl-D-alanine ligase [EC:6.3.2.10]	0.382	0.61	0.532	0.532
murG; UDP-N-acetylglucosamine–N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]	0.382	0.61	0.532	0.532
murI; glutamate racemase [EC:5.1.1.3]	0.382	0.61	0.532	0.532
murJ, mviN; putative peptidoglycan lipid II flippase	0.382	0.61	0.532	0.532
mutS2; DNA mismatch repair protein MutS2	0.382	0.61	0.532	0.532
nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]	0.382	0.61	0.532	0.532
nadE; NAD+ synthase [EC:6.3.1.5]	0.382	0.61	0.532	0.532
nagZ; beta-N-acetylhexosaminidase [EC:3.2.1.52]	0.382	0.61	0.532	0.532
napA; periplasmic nitrate reductase NapA [EC:1.7.99.-]	0.382	0.61	0.532	0.532
napB; cytochrome c-type protein NapB	0.382	0.61	0.532	0.532
napC; cytochrome c-type protein NapC	0.382	0.61	0.532	0.532
napD; periplasmic nitrate reductase NapD	0.382	0.61	0.532	0.532
napF; ferredoxin-type protein NapF	0.382	0.61	0.532	0.532
napG; ferredoxin-type protein NapG	0.382	0.61	0.532	0.532
napH; ferredoxin-type protein NapH	0.382	0.61	0.532	0.532
ncd2, npd; nitronate monooxygenase [EC:1.13.12.16]	0.382	0.61	0.532	0.532
ndk, NME; nucleoside-diphosphate kinase [EC:2.7.4.6]	0.382	0.61	0.532	0.532
neuA; N-acylneuraminate cytidylyltransferase [EC:2.7.7.43]	0.382	0.61	0.532	0.532
nfo; deoxyribonuclease IV [EC:3.1.21.2]	0.382	0.61	0.532	0.532
nhaC; Na+:H+ antiporter, NhaC family	0.382	0.61	0.532	0.532
nifB; nitrogen fixation protein NifB	0.382	0.61	0.532	0.532
nikR; CopG family transcriptional regulator, nickel-responsive regulator	0.382	0.61	0.532	0.532
norB; nitric oxide reductase subunit B [EC:1.7.2.5]	0.382	0.61	0.532	0.532
nosD; nitrous oxidase accessory protein	0.382	0.61	0.532	0.532
nosZ; nitrous-oxide reductase [EC:1.7.2.4]	0.382	0.61	0.532	0.532
nrfC; protein NrfC	0.382	0.61	0.532	0.532
nrfD; protein NrfD	0.382	0.61	0.532	0.532
nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96]	0.382	0.61	0.532	0.532
NTH; endonuclease III [EC:4.2.99.18]	0.382	0.61	0.532	0.532
nudH; putative (di)nucleoside polyphosphate hydrolase [EC:3.6.1.-]	0.382	0.61	0.532	0.532
NUDT14; UDP-sugar diphosphatase [EC:3.6.1.45]	0.382	0.61	0.532	0.532
nuoA; NADH-quinone oxidoreductase subunit A [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoB; NADH-quinone oxidoreductase subunit B [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoC; NADH-quinone oxidoreductase subunit C [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoD; NADH-quinone oxidoreductase subunit D [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoE; NADH-quinone oxidoreductase subunit E [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoF; NADH-quinone oxidoreductase subunit F [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoG; NADH-quinone oxidoreductase subunit G [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoH; NADH-quinone oxidoreductase subunit H [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoI; NADH-quinone oxidoreductase subunit I [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoJ; NADH-quinone oxidoreductase subunit J [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoK; NADH-quinone oxidoreductase subunit K [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoL; NADH-quinone oxidoreductase subunit L [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoM; NADH-quinone oxidoreductase subunit M [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nuoN; NADH-quinone oxidoreductase subunit N [EC:1.6.5.3]	0.382	0.61	0.532	0.532
nusA; N utilization substance protein A	0.382	0.61	0.532	0.532
nusB; N utilization substance protein B	0.382	0.61	0.532	0.532
nusG; transcriptional antiterminator NusG	0.382	0.61	0.532	0.532
obgE, cgtA; GTPase [EC:3.6.5.-]	0.382	0.61	0.532	0.532
ogt, MGMT; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]	0.382	0.61	0.532	0.532
oprM, emhC, ttgC, cusC, adeK, smeF, mtrE, cmeC, gesC; outer membrane protein, multidrug efflux system	0.382	0.61	0.532	0.532
osmY; hyperosmotically inducible periplasmic protein	0.382	0.61	0.532	0.532
OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3]	0.382	0.61	0.532	0.532
p19, ftrA; periplasmic iron binding protein	0.382	0.61	0.532	0.532
pal; peptidoglycan-associated lipoprotein	0.382	0.61	0.532	0.532
panB; 3-methyl-2-oxobutanoate hydroxymethyltransferase [EC:2.1.2.11]	0.382	0.61	0.532	0.532
panC; pantoate–beta-alanine ligase [EC:6.3.2.1]	0.382	0.61	0.532	0.532
panD; aspartate 1-decarboxylase [EC:4.1.1.11]	0.382	0.61	0.532	0.532
parA, soj; chromosome partitioning protein	0.382	0.61	0.532	0.532
parB, spo0J; chromosome partitioning protein, ParB family	0.382	0.61	0.532	0.532
PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]	0.382	0.61	0.532	0.532
pat; phosphinothricin acetyltransferase [EC:2.3.1.183]	0.382	0.61	0.532	0.532
patB, malY; cystathione beta-lyase [EC:4.4.1.8]	0.382	0.61	0.532	0.532
pbpC; penicillin-binding protein 1C [EC:2.4.1.129]	0.382	0.61	0.532	0.532
pbuG; putative MFS transporter, AGZA family, xanthine/uracil permease	0.382	0.61	0.532	0.532
pccA; periplasmic copper chaperone A	0.382	0.61	0.532	0.532
PDF, def; peptide deformylase [EC:3.5.1.88]	0.382	0.61	0.532	0.532
pdxK, pdxY; pyridoxine kinase [EC:2.7.1.35]	0.382	0.61	0.532	0.532
pel; pectate lyase [EC:4.2.2.2]	0.382	0.61	0.532	0.532
pepD; dipeptidase D [EC:3.4.13.-]	0.382	0.61	0.532	0.532
pepE; dipeptidase E [EC:3.4.13.21]	0.382	0.61	0.532	0.532
pepF, pepB; oligoendopeptidase F [EC:3.4.24.-]	0.382	0.61	0.532	0.532
pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]	0.382	0.61	0.532	0.532
pepT; tripeptide aminopeptidase [EC:3.4.11.4]	0.382	0.61	0.532	0.532
perR; Fur family transcriptional regulator, peroxide stress response regulator	0.382	0.61	0.532	0.532
pflA, pflC, pflE; pyruvate formate lyase activating enzyme [EC:1.97.1.4]	0.382	0.61	0.532	0.532
PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]	0.382	0.61	0.532	0.532
pglA; N,N’-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase [EC:2.4.1.290]	0.382	0.61	0.532	0.532
pglB; undecaprenyl-diphosphooligosaccharide—protein glycotransferase [EC:2.4.99.19]	0.382	0.61	0.532	0.532
pglC; undecaprenyl phosphate N,N’-diacetylbacillosamine 1-phosphate transferase [EC:2.7.8.36]	0.382	0.61	0.532	0.532
pglD; UDP-N-acetylbacillosamine N-acetyltransferase [EC:2.3.1.203]	0.382	0.61	0.532	0.532
pglE; UDP-N-acetylbacillosamine transaminase [EC:2.6.1.34]	0.382	0.61	0.532	0.532
pglF; UDP-N-acetyl-D-glucosamine 4,6-dehydratase [EC:4.2.1.135]	0.382	0.61	0.532	0.532
pglH; GalNAc-alpha-(1->4)-GalNAc-alpha-(1->3)-diNAcBac-PP-undecaprenol alpha-1,4-N-acetyl-D-galactosaminyltransferase [EC:2.4.1.292]	0.382	0.61	0.532	0.532
pglI; GalNAc5-diNAcBac-PP-undecaprenol beta-1,3-glucosyltransferase [EC:2.4.1.293]	0.382	0.61	0.532	0.532
pglJ; N-acetylgalactosamine-N,N’-diacetylbacillosaminyl-diphospho-undecaprenol 4-alpha-N-acetylgalactosaminyltransferase [EC:2.4.1.291]	0.382	0.61	0.532	0.532
pgpA; phosphatidylglycerophosphatase A [EC:3.1.3.27]	0.382	0.61	0.532	0.532
pgsA, PGS1; CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]	0.382	0.61	0.532	0.532
pheA; chorismate mutase / prephenate dehydratase [EC:5.4.99.5 4.2.1.51]	0.382	0.61	0.532	0.532
phsA, psrA; thiosulfate reductase / polysulfide reductase chain A [EC:1.8.5.5]	0.382	0.61	0.532	0.532
pilD, pppA; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]	0.382	0.61	0.532	0.532
pilT; twitching motility protein PilT	0.382	0.61	0.532	0.532
PK, pyk; pyruvate kinase [EC:2.7.1.40]	0.382	0.61	0.532	0.532
pldA; phospholipase A1/A2 [EC:3.1.1.32 3.1.1.4]	0.382	0.61	0.532	0.532
plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]	0.382	0.61	0.532	0.532
plsX; glycerol-3-phosphate acyltransferase PlsX [EC:2.3.1.15]	0.382	0.61	0.532	0.532
plsY; glycerol-3-phosphate acyltransferase PlsY [EC:2.3.1.15]	0.382	0.61	0.532	0.532
pmm-pgm; phosphomannomutase / phosphoglucomutase [EC:5.4.2.8 5.4.2.2]	0.382	0.61	0.532	0.532
pncB, NAPRT1; nicotinate phosphoribosyltransferase [EC:6.3.4.21]	0.382	0.61	0.532	0.532
pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]	0.382	0.61	0.532	0.532
pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]	0.382	0.61	0.532	0.532
polA; DNA polymerase I [EC:2.7.7.7]	0.382	0.61	0.532	0.532
por, nifJ; pyruvate-ferredoxin/flavodoxin oxidoreductase [EC:1.2.7.1 1.2.7.-]	0.382	0.61	0.532	0.532
ppa; inorganic pyrophosphatase [EC:3.6.1.1]	0.382	0.61	0.532	0.532
pphA; serine/threonine protein phosphatase 1 [EC:3.1.3.16]	0.382	0.61	0.532	0.532
PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]	0.382	0.61	0.532	0.532
ppiD; peptidyl-prolyl cis-trans isomerase D [EC:5.2.1.8]	0.382	0.61	0.532	0.532
ppk; polyphosphate kinase [EC:2.7.4.1]	0.382	0.61	0.532	0.532
ppnK, NADK; NAD+ kinase [EC:2.7.1.23]	0.382	0.61	0.532	0.532
ppnN; pyrimidine/purine-5’-nucleotide nucleosidase [EC:3.2.2.10 3.2.2.-]	0.382	0.61	0.532	0.532
ppx-gppA; exopolyphosphatase / guanosine-5’-triphosphate,3’-diphosphate pyrophosphatase [EC:3.6.1.11 3.6.1.40]	0.382	0.61	0.532	0.532
pqqL; zinc protease [EC:3.4.24.-]	0.382	0.61	0.532	0.532
praC, xylH; 4-oxalocrotonate tautomerase [EC:5.3.2.6]	0.382	0.61	0.532	0.532
prdX, proX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]	0.382	0.61	0.532	0.532
PRDX2_4, ahpC; peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15]	0.382	0.61	0.532	0.532
prfA, MTRF1, MRF1; peptide chain release factor 1	0.382	0.61	0.532	0.532
prfB; peptide chain release factor 2	0.382	0.61	0.532	0.532
priA; primosomal protein N’ (replication factor Y) (superfamily II helicase) [EC:3.6.4.-]	0.382	0.61	0.532	0.532
prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]	0.382	0.61	0.532	0.532
PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]	0.382	0.61	0.532	0.532
psd, PISD; phosphatidylserine decarboxylase [EC:4.1.1.65]	0.382	0.61	0.532	0.532
pseB; UDP-N-acetylglucosamine 4,6-dehydratase [EC:4.2.1.115]	0.382	0.61	0.532	0.532
pseC; UDP-4-amino-4,6-dideoxy-L-N-acetyl-beta-L-altrosamine transaminase [EC:2.6.1.92]	0.382	0.61	0.532	0.532
pseF; pseudaminic acid cytidylyltransferase [EC:2.7.7.81]	0.382	0.61	0.532	0.532
pseG; UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase [EC:3.6.1.57]	0.382	0.61	0.532	0.532
pseH; UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase [EC:2.3.1.202]	0.382	0.61	0.532	0.532
pseI, neuB3; pseudaminic acid synthase [EC:2.5.1.97]	0.382	0.61	0.532	0.532
psrB; polysulfide reductase chain B	0.382	0.61	0.532	0.532
psrC; polysulfide reductase chain C	0.382	0.61	0.532	0.532
pta; phosphate acetyltransferase [EC:2.3.1.8]	0.382	0.61	0.532	0.532
PTH1, pth, spoVC; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]	0.382	0.61	0.532	0.532
purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4]	0.382	0.61	0.532	0.532
purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]	0.382	0.61	0.532	0.532
purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]	0.382	0.61	0.532	0.532
purD; phosphoribosylamine—glycine ligase [EC:6.3.4.13]	0.382	0.61	0.532	0.532
purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]	0.382	0.61	0.532	0.532
purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]	0.382	0.61	0.532	0.532
purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]	0.382	0.61	0.532	0.532
purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]	0.382	0.61	0.532	0.532
purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]	0.382	0.61	0.532	0.532
purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]	0.382	0.61	0.532	0.532
putP; sodium/proline symporter	0.382	0.61	0.532	0.532
pycA; pyruvate carboxylase subunit A [EC:6.4.1.1]	0.382	0.61	0.532	0.532
pycB; pyruvate carboxylase subunit B [EC:6.4.1.1]	0.382	0.61	0.532	0.532
pydC; beta-ureidopropionase / N-carbamoyl-L-amino-acid hydrolase [EC:3.5.1.6 3.5.1.87]	0.382	0.61	0.532	0.532
pyrB, PYR2; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]	0.382	0.61	0.532	0.532
pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]	0.382	0.61	0.532	0.532
pyrF; orotidine-5’-phosphate decarboxylase [EC:4.1.1.23]	0.382	0.61	0.532	0.532
pyrG, CTPS; CTP synthase [EC:6.3.4.2]	0.382	0.61	0.532	0.532
pyrH; uridylate kinase [EC:2.7.4.22]	0.382	0.61	0.532	0.532
pyrP, uraA; uracil permease	0.382	0.61	0.532	0.532
queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]	0.382	0.61	0.532	0.532
queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]	0.382	0.61	0.532	0.532
queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]	0.382	0.61	0.532	0.532
queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]	0.382	0.61	0.532	0.532
queH; epoxyqueuosine reductase [EC:1.17.99.6]	0.382	0.61	0.532	0.532
racD; aspartate racemase [EC:5.1.1.13]	0.382	0.61	0.532	0.532
radA, sms; DNA repair protein RadA/Sms	0.382	0.61	0.532	0.532
rarD; chloramphenicol-sensitive protein RarD	0.382	0.61	0.532	0.532
RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]	0.382	0.61	0.532	0.532
rbfA; ribosome-binding factor A	0.382	0.61	0.532	0.532
rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]	0.382	0.61	0.532	0.532
recA; recombination protein RecA	0.382	0.61	0.532	0.532
recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]	0.382	0.61	0.532	0.532
recG; ATP-dependent DNA helicase RecG [EC:3.6.4.12]	0.382	0.61	0.532	0.532
recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]	0.382	0.61	0.532	0.532
recN; DNA repair protein RecN (Recombination protein N)	0.382	0.61	0.532	0.532
recR; recombination protein RecR	0.382	0.61	0.532	0.532
relA; GTP pyrophosphokinase [EC:2.7.6.5]	0.382	0.61	0.532	0.532
relE, stbE; mRNA interferase RelE/StbE	0.382	0.61	0.532	0.532
rho; transcription termination factor Rho	0.382	0.61	0.532	0.532
ribA, RIB1; GTP cyclohydrolase II [EC:3.5.4.25]	0.382	0.61	0.532	0.532
ribBA; 3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II [EC:4.1.99.12 3.5.4.25]	0.382	0.61	0.532	0.532
ribD; diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase [EC:3.5.4.26 1.1.1.193]	0.382	0.61	0.532	0.532
ribE, RIB5; riboflavin synthase [EC:2.5.1.9]	0.382	0.61	0.532	0.532
ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]	0.382	0.61	0.532	0.532
ribH, RIB4; 6,7-dimethyl-8-ribityllumazine synthase [EC:2.5.1.78]	0.382	0.61	0.532	0.532
ridA, tdcF, RIDA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]	0.382	0.61	0.532	0.532
rimM; 16S rRNA processing protein RimM	0.382	0.61	0.532	0.532
rimP; ribosome maturation factor RimP	0.382	0.61	0.532	0.532
rlmB; 23S rRNA (guanosine2251-2’-O)-methyltransferase [EC:2.1.1.185]	0.382	0.61	0.532	0.532
rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]	0.382	0.61	0.532	0.532
rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]	0.382	0.61	0.532	0.532
rlpA; rare lipoprotein A	0.382	0.61	0.532	0.532
rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]	0.382	0.61	0.532	0.532
rluC; 23S rRNA pseudouridine955/2504/2580 synthase [EC:5.4.99.24]	0.382	0.61	0.532	0.532
rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]	0.382	0.61	0.532	0.532
rmuC; DNA recombination protein RmuC	0.382	0.61	0.532	0.532
rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]	0.382	0.61	0.532	0.532
rnhA, RNASEH1; ribonuclease HI [EC:3.1.26.4]	0.382	0.61	0.532	0.532
rnhB; ribonuclease HII [EC:3.1.26.4]	0.382	0.61	0.532	0.532
rnj; ribonuclease J [EC:3.1.-.-]	0.382	0.61	0.532	0.532
rnr, vacB; ribonuclease R [EC:3.1.-.-]	0.382	0.61	0.532	0.532
rny; ribonucrease Y [EC:3.1.-.-]	0.382	0.61	0.532	0.532
rodA, mrdB; rod shape determining protein RodA	0.382	0.61	0.532	0.532
RP-L1, MRPL1, rplA; large subunit ribosomal protein L1	0.382	0.61	0.532	0.532
RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10	0.382	0.61	0.532	0.532
RP-L11, MRPL11, rplK; large subunit ribosomal protein L11	0.382	0.61	0.532	0.532
RP-L13, MRPL13, rplM; large subunit ribosomal protein L13	0.382	0.61	0.532	0.532
RP-L14, MRPL14, rplN; large subunit ribosomal protein L14	0.382	0.61	0.532	0.532
RP-L15, MRPL15, rplO; large subunit ribosomal protein L15	0.382	0.61	0.532	0.532
RP-L16, MRPL16, rplP; large subunit ribosomal protein L16	0.382	0.61	0.532	0.532
RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17	0.382	0.61	0.532	0.532
RP-L18, MRPL18, rplR; large subunit ribosomal protein L18	0.382	0.61	0.532	0.532
RP-L19, MRPL19, rplS; large subunit ribosomal protein L19	0.382	0.61	0.532	0.532
RP-L2, MRPL2, rplB; large subunit ribosomal protein L2	0.382	0.61	0.532	0.532
RP-L20, MRPL20, rplT; large subunit ribosomal protein L20	0.382	0.61	0.532	0.532
RP-L21, MRPL21, rplU; large subunit ribosomal protein L21	0.382	0.61	0.532	0.532
RP-L22, MRPL22, rplV; large subunit ribosomal protein L22	0.382	0.61	0.532	0.532
RP-L23, MRPL23, rplW; large subunit ribosomal protein L23	0.382	0.61	0.532	0.532
RP-L24, MRPL24, rplX; large subunit ribosomal protein L24	0.382	0.61	0.532	0.532
RP-L25, rplY; large subunit ribosomal protein L25	0.382	0.61	0.532	0.532
RP-L27, MRPL27, rpmA; large subunit ribosomal protein L27	0.382	0.61	0.532	0.532
RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28	0.382	0.61	0.532	0.532
RP-L29, rpmC; large subunit ribosomal protein L29	0.382	0.61	0.532	0.532
RP-L3, MRPL3, rplC; large subunit ribosomal protein L3	0.382	0.61	0.532	0.532
RP-L31, rpmE; large subunit ribosomal protein L31	0.382	0.61	0.532	0.532
RP-L32, MRPL32, rpmF; large subunit ribosomal protein L32	0.382	0.61	0.532	0.532
RP-L33, MRPL33, rpmG; large subunit ribosomal protein L33	0.382	0.61	0.532	0.532
RP-L34, MRPL34, rpmH; large subunit ribosomal protein L34	0.382	0.61	0.532	0.532
RP-L35, MRPL35, rpmI; large subunit ribosomal protein L35	0.382	0.61	0.532	0.532
RP-L4, MRPL4, rplD; large subunit ribosomal protein L4	0.382	0.61	0.532	0.532
RP-L5, MRPL5, rplE; large subunit ribosomal protein L5	0.382	0.61	0.532	0.532
RP-L6, MRPL6, rplF; large subunit ribosomal protein L6	0.382	0.61	0.532	0.532
RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12	0.382	0.61	0.532	0.532
RP-L9, MRPL9, rplI; large subunit ribosomal protein L9	0.382	0.61	0.532	0.532
RP-S1, rpsA; small subunit ribosomal protein S1	0.382	0.61	0.532	0.532
RP-S10, MRPS10, rpsJ; small subunit ribosomal protein S10	0.382	0.61	0.532	0.532
RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11	0.382	0.61	0.532	0.532
RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12	0.382	0.61	0.532	0.532
RP-S13, rpsM; small subunit ribosomal protein S13	0.382	0.61	0.532	0.532
RP-S14, MRPS14, rpsN; small subunit ribosomal protein S14	0.382	0.61	0.532	0.532
RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15	0.382	0.61	0.532	0.532
RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16	0.382	0.61	0.532	0.532
RP-S17, MRPS17, rpsQ; small subunit ribosomal protein S17	0.382	0.61	0.532	0.532
RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18	0.382	0.61	0.532	0.532
RP-S19, rpsS; small subunit ribosomal protein S19	0.382	0.61	0.532	0.532
RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2	0.382	0.61	0.532	0.532
RP-S20, rpsT; small subunit ribosomal protein S20	0.382	0.61	0.532	0.532
RP-S21, MRPS21, rpsU; small subunit ribosomal protein S21	0.382	0.61	0.532	0.532
RP-S3, rpsC; small subunit ribosomal protein S3	0.382	0.61	0.532	0.532
RP-S4, rpsD; small subunit ribosomal protein S4	0.382	0.61	0.532	0.532
RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5	0.382	0.61	0.532	0.532
RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6	0.382	0.61	0.532	0.532
RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7	0.382	0.61	0.532	0.532
RP-S8, rpsH; small subunit ribosomal protein S8	0.382	0.61	0.532	0.532
RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9	0.382	0.61	0.532	0.532
rpe, RPE; ribulose-phosphate 3-epimerase [EC:5.1.3.1]	0.382	0.61	0.532	0.532
rpiB; ribose 5-phosphate isomerase B [EC:5.3.1.6]	0.382	0.61	0.532	0.532
rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]	0.382	0.61	0.532	0.532
rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]	0.382	0.61	0.532	0.532
rpoC; DNA-directed RNA polymerase subunit beta’ [EC:2.7.7.6]	0.382	0.61	0.532	0.532
rpoD; RNA polymerase primary sigma factor	0.382	0.61	0.532	0.532
rpoN; RNA polymerase sigma-54 factor	0.382	0.61	0.532	0.532
rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]	0.382	0.61	0.532	0.532
rseP; regulator of sigma E protease [EC:3.4.24.-]	0.382	0.61	0.532	0.532
rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]	0.382	0.61	0.532	0.532
rsmI; 16S rRNA (cytidine1402-2’-O)-methyltransferase [EC:2.1.1.198]	0.382	0.61	0.532	0.532
rtpR; ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2]	0.382	0.61	0.532	0.532
ruvA; holliday junction DNA helicase RuvA [EC:3.6.4.12]	0.382	0.61	0.532	0.532
ruvB; holliday junction DNA helicase RuvB [EC:3.6.4.12]	0.382	0.61	0.532	0.532
ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.22.4]	0.382	0.61	0.532	0.532
ruvX; putative holliday junction resolvase [EC:3.1.-.-]	0.382	0.61	0.532	0.532
SAM50, TOB55, bamA; outer membrane protein insertion porin family	0.382	0.61	0.532	0.532
SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]	0.382	0.61	0.532	0.532
sat, met3; sulfate adenylyltransferase [EC:2.7.7.4]	0.382	0.61	0.532	0.532
sbmA, bacA; peptide/bleomycin uptake transporter	0.382	0.61	0.532	0.532
SCO1_2; protein SCO1/2	0.382	0.61	0.532	0.532
sdhA, frdA; succinate dehydrogenase / fumarate reductase, flavoprotein subunit [EC:1.3.5.1 1.3.5.4]	0.382	0.61	0.532	0.532
sdhB, frdB; succinate dehydrogenase / fumarate reductase, iron-sulfur subunit [EC:1.3.5.1 1.3.5.4]	0.382	0.61	0.532	0.532
sdhC, frdC; succinate dehydrogenase / fumarate reductase, cytochrome b subunit	0.382	0.61	0.532	0.532
secA; preprotein translocase subunit SecA	0.382	0.61	0.532	0.532
secD; preprotein translocase subunit SecD	0.382	0.61	0.532	0.532
secE; preprotein translocase subunit SecE	0.382	0.61	0.532	0.532
secF; preprotein translocase subunit SecF	0.382	0.61	0.532	0.532
secG; preprotein translocase subunit SecG	0.382	0.61	0.532	0.532
secY; preprotein translocase subunit SecY	0.382	0.61	0.532	0.532
selA; L-seryl-tRNA(Ser) seleniumtransferase [EC:2.9.1.1]	0.382	0.61	0.532	0.532
selB, EEFSEC; selenocysteine-specific elongation factor	0.382	0.61	0.532	0.532
selD, SEPHS; selenide, water dikinase [EC:2.7.9.3]	0.382	0.61	0.532	0.532
selU; tRNA 2-selenouridine synthase [EC:2.9.1.-]	0.382	0.61	0.532	0.532
serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]	0.382	0.61	0.532	0.532
serB, PSPH; phosphoserine phosphatase [EC:3.1.3.3]	0.382	0.61	0.532	0.532
serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52]	0.382	0.61	0.532	0.532
sixA; phosphohistidine phosphatase [EC:3.1.3.-]	0.382	0.61	0.532	0.532
slt; soluble lytic murein transglycosylase [EC:4.2.2.-]	0.382	0.61	0.532	0.532
slyD; FKBP-type peptidyl-prolyl cis-trans isomerase SlyD [EC:5.2.1.8]	0.382	0.61	0.532	0.532
smf; DNA processing protein	0.382	0.61	0.532	0.532
smpB; SsrA-binding protein	0.382	0.61	0.532	0.532
SOD1; superoxide dismutase, Cu-Zn family [EC:1.15.1.1]	0.382	0.61	0.532	0.532
SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]	0.382	0.61	0.532	0.532
sotB; MFS transporter, DHA1 family, L-arabinose/isopropyl-beta-D-thiogalactopyranoside export protein	0.382	0.61	0.532	0.532
speA; arginine decarboxylase [EC:4.1.1.19]	0.382	0.61	0.532	0.532
sppA; protease IV [EC:3.4.21.-]	0.382	0.61	0.532	0.532
SRP54, ffh; signal recognition particle subunit SRP54 [EC:3.6.5.4]	0.382	0.61	0.532	0.532
ssb; single-strand DNA-binding protein	0.382	0.61	0.532	0.532
sstT; serine/threonine transporter	0.382	0.61	0.532	0.532
ssuA; sulfonate transport system substrate-binding protein	0.382	0.61	0.532	0.532
ssuB; sulfonate transport system ATP-binding protein [EC:3.6.3.-]	0.382	0.61	0.532	0.532
ssuC; sulfonate transport system permease protein	0.382	0.61	0.532	0.532
stbD; antitoxin StbD	0.382	0.61	0.532	0.532
STE24; STE24 endopeptidase [EC:3.4.24.84]	0.382	0.61	0.532	0.532
surE; 5’-nucleotidase [EC:3.1.3.5]	0.382	0.61	0.532	0.532
tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]	0.382	0.61	0.532	0.532
TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]	0.382	0.61	0.532	0.532
tatA; sec-independent protein translocase protein TatA	0.382	0.61	0.532	0.532
tatB; sec-independent protein translocase protein TatB	0.382	0.61	0.532	0.532
tatC; sec-independent protein translocase protein TatC	0.382	0.61	0.532	0.532
tatD; TatD DNase family protein [EC:3.1.21.-]	0.382	0.61	0.532	0.532
TC.AGCS; alanine or glycine:cation symporter, AGCS family	0.382	0.61	0.532	0.532
TC.BAT1; bacterial/archaeal transporter family protein	0.382	0.61	0.532	0.532
TC.CPA1; monovalent cation:H+ antiporter, CPA1 family	0.382	0.61	0.532	0.532
TC.DCUC, dcuC, dcuD; C4-dicarboxylate transporter, DcuC family	0.382	0.61	0.532	0.532
TC.FEV.OM; iron complex outermembrane recepter protein	0.382	0.61	0.532	0.532
TC.FEV.OM1, fhuE, fpvA, fptA; outer-membrane receptor for ferric coprogen and ferric-rhodotorulic acid	0.382	0.61	0.532	0.532
TC.FEV.OM2, cirA, cfrA, hmuR; outer membrane receptor for ferrienterochelin and colicins	0.382	0.61	0.532	0.532
TC.FEV.OM3, tbpA, hemR, lbpA, hpuB, bhuR, hugA, hmbR; hemoglobin/transferrin/lactoferrin receptor protein	0.382	0.61	0.532	0.532
TC.GNTP; gluconate:H+ symporter, GntP family	0.382	0.61	0.532	0.532
TC.HAE1; hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family	0.382	0.61	0.532	0.532
TC.KEF; monovalent cation:H+ antiporter-2, CPA2 family	0.382	0.61	0.532	0.532
TC.NSS; neurotransmitter:Na+ symporter, NSS family	0.382	0.61	0.532	0.532
TC.OOP; OmpA-OmpF porin, OOP family	0.382	0.61	0.532	0.532
TC.PIT; inorganic phosphate transporter, PiT family	0.382	0.61	0.532	0.532
tgt, QTRT1; queuine tRNA-ribosyltransferase [EC:2.4.2.29]	0.382	0.61	0.532	0.532
thiC; phosphomethylpyrimidine synthase [EC:4.1.99.17]	0.382	0.61	0.532	0.532
thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]	0.382	0.61	0.532	0.532
thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]	0.382	0.61	0.532	0.532
thiF; sulfur carrier protein ThiS adenylyltransferase [EC:2.7.7.73]	0.382	0.61	0.532	0.532
thiG; thiazole synthase [EC:2.8.1.10]	0.382	0.61	0.532	0.532
thiH; 2-iminoacetate synthase [EC:4.1.99.19]	0.382	0.61	0.532	0.532
thiJ; protein deglycase [EC:3.5.1.124]	0.382	0.61	0.532	0.532
thiL; thiamine-monophosphate kinase [EC:2.7.4.16]	0.382	0.61	0.532	0.532
thiS; sulfur carrier protein	0.382	0.61	0.532	0.532
thrB1; homoserine kinase [EC:2.7.1.39]	0.382	0.61	0.532	0.532
thrC; threonine synthase [EC:4.2.3.1]	0.382	0.61	0.532	0.532
thyX, thy1; thymidylate synthase (FAD) [EC:2.1.1.148]	0.382	0.61	0.532	0.532
tig; trigger factor	0.382	0.61	0.532	0.532
tilS, mesJ; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]	0.382	0.61	0.532	0.532
tlyA; 23S rRNA (cytidine1920-2’-O)/16S rRNA (cytidine1409-2’-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]	0.382	0.61	0.532	0.532
tmk, DTYMK; dTMP kinase [EC:2.7.4.9]	0.382	0.61	0.532	0.532
tolB; TolB protein	0.382	0.61	0.532	0.532
tonB; periplasmic protein TonB	0.382	0.61	0.532	0.532
topA; DNA topoisomerase I [EC:5.99.1.2]	0.382	0.61	0.532	0.532
torC; trimethylamine-N-oxide reductase (cytochrome c), cytochrome c-type subunit TorC	0.382	0.61	0.532	0.532
torZ; trimethylamine-N-oxide reductase (cytochrome c) [EC:1.7.2.3]	0.382	0.61	0.532	0.532
TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]	0.382	0.61	0.532	0.532
tpx; thiol peroxidase, atypical 2-Cys peroxiredoxin [EC:1.11.1.15]	0.382	0.61	0.532	0.532
trmA; tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35]	0.382	0.61	0.532	0.532
trmB, METTL1; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]	0.382	0.61	0.532	0.532
trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]	0.382	0.61	0.532	0.532
trmL, cspR; tRNA (cytidine/uridine-2’-O-)-methyltransferase [EC:2.1.1.207]	0.382	0.61	0.532	0.532
trpA; tryptophan synthase alpha chain [EC:4.2.1.20]	0.382	0.61	0.532	0.532
trpB; tryptophan synthase beta chain [EC:4.2.1.20]	0.382	0.61	0.532	0.532
trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]	0.382	0.61	0.532	0.532
trpE; anthranilate synthase component I [EC:4.1.3.27]	0.382	0.61	0.532	0.532
trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]	0.382	0.61	0.532	0.532
trpGD; anthranilate synthase/phosphoribosyltransferase [EC:4.1.3.27 2.4.2.18]	0.382	0.61	0.532	0.532
truA, PUS1; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]	0.382	0.61	0.532	0.532
truB, PUS4, TRUB1; tRNA pseudouridine55 synthase [EC:5.4.99.25]	0.382	0.61	0.532	0.532
truD, PUS7; tRNA pseudouridine13 synthase [EC:5.4.99.27]	0.382	0.61	0.532	0.532
trxA; thioredoxin 1	0.382	0.61	0.532	0.532
trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9]	0.382	0.61	0.532	0.532
tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE	0.382	0.61	0.532	0.532
tsf, TSFM; elongation factor Ts	0.382	0.61	0.532	0.532
tspA; uncharacterized membrane protein	0.382	0.61	0.532	0.532
ttdA; L(+)-tartrate dehydratase alpha subunit [EC:4.2.1.32]	0.382	0.61	0.532	0.532
ttdB; L(+)-tartrate dehydratase beta subunit [EC:4.2.1.32]	0.382	0.61	0.532	0.532
ttrA; tetrathionate reductase subunit A	0.382	0.61	0.532	0.532
ttrB; tetrathionate reductase subunit B	0.382	0.61	0.532	0.532
tuf, TUFM; elongation factor Tu	0.382	0.61	0.532	0.532
tupA, vupA; tungstate transport system substrate-binding protein	0.382	0.61	0.532	0.532
tupB, vupB; tungstate transport system permease protein	0.382	0.61	0.532	0.532
tupC, vupC; tungstate transport system ATP-binding protein [EC:3.6.3.55]	0.382	0.61	0.532	0.532
typA, bipA; GTP-binding protein	0.382	0.61	0.532	0.532
tyrA2; prephenate dehydrogenase [EC:1.3.1.12]	0.382	0.61	0.532	0.532
ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]	0.382	0.61	0.532	0.532
ubiD; 4-hydroxy-3-polyprenylbenzoate decarboxylase [EC:4.1.1.98]	0.382	0.61	0.532	0.532
ubiE; demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201]	0.382	0.61	0.532	0.532
ubiX, bsdB, PAD1; flavin prenyltransferase [EC:2.5.1.129]	0.382	0.61	0.532	0.532
UGDH, ugd; UDPglucose 6-dehydrogenase [EC:1.1.1.22]	0.382	0.61	0.532	0.532
UGP2, galU, galF; UTP–glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]	0.382	0.61	0.532	0.532
umuC; DNA polymerase V	0.382	0.61	0.532	0.532
UNG, UDG; uracil-DNA glycosylase [EC:3.2.2.27]	0.382	0.61	0.532	0.532
upp, UPRT; uracil phosphoribosyltransferase [EC:2.4.2.9]	0.382	0.61	0.532	0.532
uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]	0.382	0.61	0.532	0.532
UQCRFS1, RIP1, petA; ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2]	0.382	0.61	0.532	0.532
URA4, pyrC; dihydroorotase [EC:3.5.2.3]	0.382	0.61	0.532	0.532
uup; ABC transport system ATP-binding/permease protein	0.382	0.61	0.532	0.532
uvrA; excinuclease ABC subunit A	0.382	0.61	0.532	0.532
uvrB; excinuclease ABC subunit B	0.382	0.61	0.532	0.532
uvrC; excinuclease ABC subunit C	0.382	0.61	0.532	0.532
uvrD, pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]	0.382	0.61	0.532	0.532
VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]	0.382	0.61	0.532	0.532
vasD, lip; type VI secretion system protein VasD	0.382	0.61	0.532	0.532
vasJ; type VI secretion system protein VasJ	0.382	0.61	0.532	0.532
vgrG; type VI secretion system secreted protein VgrG	0.382	0.61	0.532	0.532
waaC, rfaC; heptosyltransferase I [EC:2.4.-.-]	0.382	0.61	0.532	0.532
waaF, rfaF; heptosyltransferase II [EC:2.4.-.-]	0.382	0.61	0.532	0.532
waaG, rfaG; UDP-glucose:(heptosyl)LPS alpha-1,3-glucosyltransferase [EC:2.4.1.-]	0.382	0.61	0.532	0.532
waaQ, rfaQ; heptosyltransferase III [EC:2.4.-.-]	0.382	0.61	0.532	0.532
WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]	0.382	0.61	0.532	0.532
wbpO; UDP-N-acetyl-D-galactosamine dehydrogenase [EC:1.1.1.-]	0.382	0.61	0.532	0.532
xerD; integrase/recombinase XerD	0.382	0.61	0.532	0.532
xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]	0.382	0.61	0.532	0.532
xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]	0.382	0.61	0.532	0.532
yafQ; mRNA interferase YafQ [EC:3.1.-.-]	0.382	0.61	0.532	0.532
yagU; putative membrane protein	0.382	0.61	0.532	0.532
yajC; preprotein translocase subunit YajC	0.382	0.61	0.532	0.532
yajG; uncharacterized lipoprotein	0.382	0.61	0.532	0.532
yajQ; cyclic-di-GMP-binding protein	0.382	0.61	0.532	0.532
YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]	0.382	0.61	0.532	0.532
ybaK, ebsC; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]	0.382	0.61	0.532	0.532
ybeY, yqfG; probable rRNA maturation factor	0.382	0.61	0.532	0.532
ybgC; acyl-CoA thioester hydrolase [EC:3.1.2.-]	0.382	0.61	0.532	0.532
ycaJ; putative ATPase	0.382	0.61	0.532	0.532
yccA; modulator of FtsH protease	0.382	0.61	0.532	0.532
ychF; ribosome-binding ATPase	0.382	0.61	0.532	0.532
ychN; uncharacterized protein involved in oxidation of intracellular sulfur	0.382	0.61	0.532	0.532
yciA; acyl-CoA thioesterase YciA [EC:3.1.2.-]	0.382	0.61	0.532	0.532
yfiH; polyphenol oxidase [EC:1.10.3.-]	0.382	0.61	0.532	0.532
yggS, PROSC; PLP dependent protein	0.382	0.61	0.532	0.532
yggT; YggT family protein	0.382	0.61	0.532	0.532
yhbH; putative sigma-54 modulation protein	0.382	0.61	0.532	0.532
yhcO; ribonuclease inhibitor	0.382	0.61	0.532	0.532
yidC, spoIIIJ, OXA1, ccfA; YidC/Oxa1 family membrane protein insertase	0.382	0.61	0.532	0.532
ykkC; paired small multidrug resistance pump	0.382	0.61	0.532	0.532
ykkD; paired small multidrug resistance pump	0.382	0.61	0.532	0.532
ynaI, mscMJ; MscS family membrane protein	0.382	0.61	0.532	0.532
yoeB; toxin YoeB [EC:3.1.-.-]	0.382	0.61	0.532	0.532
yojI; multidrug/microcin transport system ATP-binding/permease protein	0.382	0.61	0.532	0.532
yraN; putative endonuclease	0.382	0.61	0.532	0.532
yuiF; putative amino acid transporter	0.382	0.61	0.532	0.532
znuA; zinc transport system substrate-binding protein	0.382	0.61	0.532	0.532
znuB; zinc transport system permease protein	0.382	0.61	0.532	0.532
znuC; zinc transport system ATP-binding protein [EC:3.6.3.-]	0.382	0.61	0.532	0.532
zur; Fur family transcriptional regulator, zinc uptake regulator	0.382	0.61	0.532	0.532

# merge with tb.ra for full results table
full.res <- left_join(tb.ra, results.out, by = "description")

write.csv(full.res, "output/picrust_ko_stratefied_campy_data_results.csv", row.names = F)

Session information

sessionInfo()

R version 4.0.5 (2021-03-31)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19042)

Matrix products: default

locale:
[1] LC_COLLATE=English_United States.1252 
[2] LC_CTYPE=English_United States.1252   
[3] LC_MONETARY=English_United States.1252
[4] LC_NUMERIC=C                          
[5] LC_TIME=English_United States.1252    

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] cowplot_1.1.1     dendextend_1.14.0 ggdendro_0.1.22   reshape2_1.4.4   
 [5] car_3.0-10        carData_3.0-4     gvlma_1.0.0.3     patchwork_1.1.1  
 [9] viridis_0.5.1     viridisLite_0.3.0 gridExtra_2.3     xtable_1.8-4     
[13] kableExtra_1.3.4  MASS_7.3-53.1     data.table_1.14.0 readxl_1.3.1     
[17] forcats_0.5.1     stringr_1.4.0     dplyr_1.0.5       purrr_0.3.4      
[21] readr_1.4.0       tidyr_1.1.3       tibble_3.1.0      ggplot2_3.3.3    
[25] tidyverse_1.3.0   lmerTest_3.1-3    lme4_1.1-26       Matrix_1.3-2     
[29] vegan_2.5-7       lattice_0.20-41   permute_0.9-5     phyloseq_1.34.0  
[33] workflowr_1.6.2  

loaded via a namespace (and not attached):
  [1] minqa_1.2.4         colorspace_2.0-0    rio_0.5.26         
  [4] ellipsis_0.3.1      rprojroot_2.0.2     XVector_0.30.0     
  [7] fs_1.5.0            rstudioapi_0.13     farver_2.1.0       
 [10] fansi_0.4.2         lubridate_1.7.10    xml2_1.3.2         
 [13] codetools_0.2-18    splines_4.0.5       knitr_1.31         
 [16] ade4_1.7-16         jsonlite_1.7.2      nloptr_1.2.2.2     
 [19] broom_0.7.5         cluster_2.1.1       dbplyr_2.1.0       
 [22] BiocManager_1.30.10 compiler_4.0.5      httr_1.4.2         
 [25] backports_1.2.1     assertthat_0.2.1    cli_2.3.1          
 [28] later_1.1.0.1       htmltools_0.5.1.1   prettyunits_1.1.1  
 [31] tools_4.0.5         igraph_1.2.6        gtable_0.3.0       
 [34] glue_1.4.2          Rcpp_1.0.6          Biobase_2.50.0     
 [37] cellranger_1.1.0    jquerylib_0.1.3     vctrs_0.3.6        
 [40] Biostrings_2.58.0   rhdf5filters_1.2.0  multtest_2.46.0    
 [43] svglite_2.0.0       ape_5.4-1           nlme_3.1-152       
 [46] iterators_1.0.13    xfun_0.21           ps_1.6.0           
 [49] openxlsx_4.2.3      rvest_1.0.0         lifecycle_1.0.0    
 [52] statmod_1.4.35      zlibbioc_1.36.0     scales_1.1.1       
 [55] hms_1.0.0           promises_1.2.0.1    parallel_4.0.5     
 [58] biomformat_1.18.0   rhdf5_2.34.0        curl_4.3           
 [61] yaml_2.2.1          sass_0.3.1          stringi_1.5.3      
 [64] highr_0.8           S4Vectors_0.28.1    foreach_1.5.1      
 [67] BiocGenerics_0.36.0 zip_2.1.1           boot_1.3-27        
 [70] systemfonts_1.0.1   rlang_0.4.10        pkgconfig_2.0.3    
 [73] evaluate_0.14       Rhdf5lib_1.12.1     labeling_0.4.2     
 [76] tidyselect_1.1.0    plyr_1.8.6          magrittr_2.0.1     
 [79] R6_2.5.0            IRanges_2.24.1      generics_0.1.0     
 [82] DBI_1.1.1           foreign_0.8-81      pillar_1.5.1       
 [85] haven_2.3.1         withr_2.4.1         mgcv_1.8-34        
 [88] abind_1.4-5         survival_3.2-10     modelr_0.1.8       
 [91] crayon_1.4.1        utf8_1.1.4          rmarkdown_2.7      
 [94] progress_1.2.2      grid_4.0.5          git2r_0.28.0       
 [97] webshot_0.5.2       reprex_1.0.0        digest_0.6.27      
[100] httpuv_1.5.5        numDeriv_2016.8-1.1 stats4_4.0.5       
[103] munsell_0.5.0       bslib_0.2.4