Last updated: 2021-05-20

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File	Version	Author	Date	Message
Rmd	5a00a1b	noah-padgett	2021-04-29	updated figured and stuff
html	5a00a1b	noah-padgett	2021-04-29	updated figured and stuff
Rmd	ea63e54	noah-padgett	2021-04-15	updated picrust results
html	ea63e54	noah-padgett	2021-04-15	updated picrust results

i. Mean relative abundance in Tumors

ii. Standard error of mean in Tumors

iii. Mean relative abundance in Non-tumors

iv. Standard error of mean in Non-tumors

v. GLM differential abundance analysis between Tumor vs Non-tumor (Patient=Fixed effect)
  1. P-value
  2. FDR corrected q-value
vi. GLMM differential abundance analysis between Tumor vs Non-tumor (Patient=Random Effect)
  1.P-value
  2. FDR corrected q-value

Part 1 EC Data

# note: must rename function to func (or something else) because "function" is a reserved name in R and can't be used.

descriptions <- readr::read_tsv("data/PICRUST/ec_pred_metagenome_unstrat_descrip.tsv")[,1:2] %>%
  distinct()


-- Column specification --------------------------------------------------------
cols(
  .default = col_double(),
  `function` = col_character(),
  description = col_character()
)
i Use `spec()` for the full column specifications.

colnames(descriptions) <- c("func", "description")

pi.dat <- readxl::read_xlsx("data/PICRUST-Stratified/EC_strepto.xlsx")
colnames(pi.dat) <- c("func",  colnames(pi.dat)[-c(1)])

# add descriptions to dataframe
pi.dat <- left_join(pi.dat, descriptions, by="func")
pi.dat <- pi.dat[,c(1,161,3:160)]

# aggregate descriptions to get 1 description per row - unique;y defined.
pi.dat <- pi.dat %>%
  group_by(description) %>%
  summarise(across(`1.S37.Jun172016`:`99.D01.S37.Jun232016`,.fns = sum))

# make long format
pi.dat <- pi.dat %>%
  pivot_longer(
    cols=`1.S37.Jun172016`:`99.D01.S37.Jun232016`,
    names_to = "ID",
    values_to = "Abundance"
  )
d <- as.data.frame(dat.16s)
mydata <- full_join(pi.dat, d)

Joining, by = "ID"

Warning in class(x) <- c(setdiff(subclass, tibble_class), tibble_class): Setting
class(x) to multiple strings ("tbl_df", "tbl", ...); result will no longer be an
S4 object

mydata <- mydata %>%
  mutate(
    ID.n = as.numeric(as.factor(ID)),
    description.n = as.numeric(as.factor(description))
  ) %>%
  group_by(ID) %>%
  mutate(
    dem = ifelse(sum(Abundance)==0, 1, sum(Abundance)),
    RelAbundance = Abundance/dem*100) %>%
  ungroup()%>%
  group_by(description)%>%
  mutate(avgRA = mean(RelAbundance))

Abundance

I needed to change from relative abundance to abundance due to so many individuals having 0 counts for all descriptions.

d <- mydata %>%
  filter(description=="DNA-directed DNA polymerase")

t.test(d$RelAbundance ~ d$tumor.cat)


    Welch Two Sample t-test

data:  d$RelAbundance by d$tumor.cat
t = -1.15, df = 153, p-value = 0.25
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
 -0.239167  0.063572
sample estimates:
mean in group Non-Tumor     mean in group Tumor 
                 1.3750                  1.4628

# Run on all descriptions
tb.ra1 <- mydata %>%
  group_by(description) %>%
  summarise(ng = n(),
            Overall.M = mean(RelAbundance),
            Overall.SE = sd(RelAbundance)/sqrt(ng))
tb.ra2m <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(M = mean(RelAbundance)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = M)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2se <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n(),SE = sd(RelAbundance)/sqrt(ng)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = SE)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2var <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n(), VAR = var(RelAbundance)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = VAR)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2ng <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n()) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = ng)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra <- left_join(tb.ra1, tb.ra2m)

Joining, by = "description"

tb.ra <- cbind(tb.ra, tb.ra2se[,-1])
tb.ra <- cbind(tb.ra, tb.ra2var[,-1])
tb.ra <- cbind(tb.ra, tb.ra2ng[,-1]) 

colnames(tb.ra) <- c("description", "ng", "Overall Mean", "Overall SE", "Non-Tumor Mean", "Tumor Mean", "Non-Tumor SE", "Tumor SE","Non-Tumor Var", "Tumor Var", "Non-Tumor Ng", "Tumor Ng")
tb.ra <- tb.ra %>%
  arrange(desc(`Overall Mean`))
tb.ra <- tb.ra[, c("description", "Overall Mean", "Overall SE","Tumor Mean","Tumor Var", "Tumor SE","Tumor Ng", "Non-Tumor Mean","Non-Tumor Var", "Non-Tumor SE", "Non-Tumor Ng")]

# compute t-test
tb.ra <- tb.ra %>%
  mutate(
    SEpooled = sqrt(`Tumor Var`/`Tumor Ng` + `Non-Tumor Var`/`Non-Tumor Ng`),
    t = (`Tumor Mean` - `Non-Tumor Mean`)/(SEpooled),
    df = ((`Tumor Var`/`Tumor Ng` + `Non-Tumor Var`/`Non-Tumor Ng`)**2)/(((`Tumor Var`/`Tumor Ng`)**2)/(`Tumor Ng`-1) + ((`Non-Tumor Var`/`Non-Tumor Ng`)**2)/(`Non-Tumor Ng`-1)),
    p = pt(q = abs(t), df=df, lower.tail = F)*2,
    fdr_p = p.adjust(p, method="fdr")
  )


kable(tb.ra, format="html", digits=5, caption="Stratefied EC Data - Streptococcus sanguinis : Average RelAbundance of Each Description (sorted in descending order)") %>%
  kable_styling(full_width = T) %>%
  scroll_box(width = "100%", height="600px")

Stratefied EC Data - Streptococcus sanguinis : Average RelAbundance of Each Description (sorted in descending order)
description	Overall Mean	Overall SE	Tumor Mean	Tumor Var	Tumor SE	Tumor Ng	Non-Tumor Mean	Non-Tumor Var	Non-Tumor SE	Non-Tumor Ng	SEpooled	t	df	p	fdr_p
DNA-directed DNA polymerase	1.41114	0.03923	1.46282	0.18244	0.05298	65	1.37502	0.28494	0.05535	93	0.07662	1.14588	153.09	0.25363	0.32233
Protein-N(pi)-phosphohistidine–sugar phosphotransferase	1.41114	0.03923	1.46282	0.18244	0.05298	65	1.37502	0.28494	0.05535	93	0.07662	1.14588	153.09	0.25363	0.32233
DNA helicase	1.25435	0.03488	1.30028	0.14415	0.04709	65	1.22224	0.22514	0.04920	93	0.06811	1.14588	153.09	0.25363	0.32233
Histidine kinase	1.18524	0.03343	1.23217	0.13358	0.04533	65	1.15244	0.20570	0.04703	93	0.06532	1.22065	152.78	0.22410	0.32233
8-oxo-dGTP diphosphatase	0.90386	0.02782	0.92286	0.09136	0.03749	65	0.89059	0.14463	0.03944	93	0.05441	0.59311	153.36	0.55398	0.66781
Polar-amino-acid-transporting ATPase	0.64558	0.01982	0.67627	0.04827	0.02725	65	0.62412	0.07120	0.02767	93	0.03884	1.34273	151.77	0.18136	0.32233
DNA-directed RNA polymerase	0.62717	0.01744	0.65014	0.03604	0.02355	65	0.61112	0.05628	0.02460	93	0.03405	1.14588	153.09	0.25363	0.32233
Type I site-specific deoxyribonuclease	0.60842	0.01779	0.62364	0.03723	0.02393	65	0.59778	0.05920	0.02523	93	0.03478	0.74374	153.45	0.45817	0.57637
Phosphoglycerate mutase (2,3-diphosphoglycerate-independent)	0.52117	0.01725	0.52968	0.03544	0.02335	65	0.51522	0.05548	0.02442	93	0.03379	0.42781	153.13	0.66939	0.80453
Galactose-6-phosphate isomerase	0.48896	0.01582	0.51392	0.03117	0.02190	65	0.47151	0.04507	0.02201	93	0.03105	1.36571	151.25	0.17406	0.32233
23S rRNA pseudouridine(1911/1915/1917) synthase	0.47038	0.01308	0.48761	0.02027	0.01766	65	0.45834	0.03166	0.01845	93	0.02554	1.14588	153.09	0.25363	0.32233
Asparaginyl-tRNA synthase (glutamine-hydrolyzing)	0.47038	0.01308	0.48761	0.02027	0.01766	65	0.45834	0.03166	0.01845	93	0.02554	1.14588	153.09	0.25363	0.32233
Cysteine desulfurase	0.47038	0.01308	0.48761	0.02027	0.01766	65	0.45834	0.03166	0.01845	93	0.02554	1.14588	153.09	0.25363	0.32233
Glutaminyl-tRNA synthase (glutamine-hydrolyzing)	0.47038	0.01308	0.48761	0.02027	0.01766	65	0.45834	0.03166	0.01845	93	0.02554	1.14588	153.09	0.25363	0.32233
Peptidylprolyl isomerase	0.47038	0.01308	0.48761	0.02027	0.01766	65	0.45834	0.03166	0.01845	93	0.02554	1.14588	153.09	0.25363	0.32233
Tryptophan synthase	0.47038	0.01308	0.48761	0.02027	0.01766	65	0.45834	0.03166	0.01845	93	0.02554	1.14588	153.09	0.25363	0.32233
Acetyl-CoA carboxylase	0.47029	0.01308	0.48751	0.02026	0.01766	65	0.45826	0.03165	0.01845	93	0.02554	1.14576	153.09	0.25368	0.32233
Ribosomal-protein-alanine N-acetyltransferase	0.45198	0.01391	0.46148	0.02284	0.01874	65	0.44534	0.03617	0.01972	93	0.02721	0.59321	153.37	0.55391	0.66781
Serine-type D-Ala-D-Ala carboxypeptidase	0.45198	0.01391	0.46148	0.02284	0.01874	65	0.44534	0.03617	0.01972	93	0.02721	0.59321	153.37	0.55391	0.66781
Site-specific DNA-methyltransferase (adenine-specific)	0.45171	0.01390	0.46120	0.02285	0.01875	65	0.44508	0.03609	0.01970	93	0.02720	0.59258	153.32	0.55433	0.66781
Phosphate-transporting ATPase	0.40119	0.01197	0.41940	0.01748	0.01640	65	0.38845	0.02609	0.01675	93	0.02344	1.32042	152.06	0.18868	0.32233
Ribonuclease H	0.40119	0.01197	0.41940	0.01748	0.01640	65	0.38845	0.02609	0.01675	93	0.02344	1.32042	152.06	0.18868	0.32233
Alcohol dehydrogenase	0.38278	0.01094	0.39327	0.01403	0.01469	65	0.37545	0.02237	0.01551	93	0.02136	0.83441	153.51	0.40534	0.51131
H(+)-transporting two-sector ATPase	0.38278	0.01094	0.39327	0.01403	0.01469	65	0.37545	0.02237	0.01551	93	0.02136	0.83441	153.51	0.40534	0.51131
[Formate-C-acetyltransferase]-activating enzyme	0.38269	0.01094	0.39318	0.01403	0.01469	65	0.37536	0.02236	0.01550	93	0.02136	0.83422	153.50	0.40546	0.51131
Transketolase	0.33190	0.01208	0.35111	0.01846	0.01685	65	0.31848	0.02603	0.01673	93	0.02375	1.37397	150.57	0.17149	0.32233
Uracil phosphoribosyltransferase	0.31367	0.00872	0.32516	0.00902	0.01178	65	0.30564	0.01408	0.01230	93	0.01703	1.14600	153.08	0.25358	0.32233
(R)-2-methylmalate dehydratase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
16S rRNA pseudouridine(516) synthase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
3-isopropylmalate dehydratase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
3-oxoacyl-[acyl-carrier-protein] reductase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Acetolactate synthase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Anthranilate synthase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
D-alanine–poly(phosphoribitol) ligase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Dihydrofolate synthase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
DNA-(apurinic or apyrimidinic site) lyase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
DNA topoisomerase (ATP-hydrolyzing)	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Exodeoxyribonuclease VII	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Glucose-1-phosphate adenylyltransferase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Glycerol-3-phosphate 1-O-acyltransferase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Glycine–tRNA ligase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
GTP diphosphokinase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Iron-chelate-transporting ATPase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
L-serine ammonia-lyase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Peptide-methionine (R)-S-oxide reductase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Peptide-methionine (S)-S-oxide reductase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Peptide deformylase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Phenylalanine–tRNA ligase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Phosphoribosylanthranilate isomerase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Protein-serine/threonine phosphatase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Purine-nucleoside phosphorylase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Pyruvate dehydrogenase (acetyl-transferring)	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Ribonucleoside-diphosphate reductase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Ribonucleoside-triphosphate reductase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Ribose-phosphate diphosphokinase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
RNA helicase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Tetrahydrofolate synthase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Thioredoxin-disulfide reductase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
UDP-glucose 4-epimerase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
Undecaprenyl-diphosphate phosphatase	0.31359	0.00872	0.32507	0.00901	0.01177	65	0.30556	0.01407	0.01230	93	0.01703	1.14588	153.09	0.25363	0.32233
3-deoxy-7-phosphoheptulonate synthase	0.31350	0.00872	0.32498	0.00900	0.01177	65	0.30548	0.01407	0.01230	93	0.01702	1.14570	153.09	0.25371	0.32233
6-phospho-beta-glucosidase	0.29518	0.01039	0.29894	0.01296	0.01412	65	0.29256	0.02007	0.01469	93	0.02038	0.31338	152.91	0.75442	0.84628
Pullulanase	0.29509	0.01039	0.29885	0.01297	0.01412	65	0.29247	0.02004	0.01468	93	0.02037	0.31305	152.87	0.75467	0.84628
Sortase A	0.29509	0.01039	0.29885	0.01297	0.01412	65	0.29247	0.02004	0.01468	93	0.02037	0.31305	152.87	0.75467	0.84628
D-alanine–D-alanine ligase	0.24439	0.00791	0.25687	0.00778	0.01094	65	0.23567	0.01127	0.01101	93	0.01552	1.36556	151.31	0.17410	0.32233
4-hydroxy-tetrahydrodipicolinate reductase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
ADP-ribose diphosphatase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Arsenate reductase (glutaredoxin)	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Aspartate–tRNA ligase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Beta-galactosidase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Formate–tetrahydrofolate ligase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Glutamate dehydrogenase (NADP(+))	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Glycogen phosphorylase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
N(6)-L-threonylcarbamoyladenine synthase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Protein-tyrosine-phosphatase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Pyridoxal kinase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Signal peptidase I	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Xaa-Pro dipeptidyl-peptidase	0.22599	0.00695	0.23074	0.00571	0.00937	65	0.22267	0.00904	0.00986	93	0.01360	0.59321	153.37	0.55391	0.66781
Formate C-acetyltransferase	0.22590	0.00695	0.23065	0.00571	0.00937	65	0.22258	0.00903	0.00985	93	0.01360	0.59280	153.34	0.55419	0.66781
Exo-alpha-sialidase	0.17520	0.00891	0.18867	0.01034	0.01262	65	0.16578	0.01397	0.01226	93	0.01759	1.30079	149.31	0.19534	0.32233
Hydroxyethylthiazole kinase	0.17520	0.00891	0.18867	0.01034	0.01262	65	0.16578	0.01397	0.01226	93	0.01759	1.30079	149.31	0.19534	0.32233
Pyridoxal 5’-phosphate synthase (glutamine hydrolyzing)	0.17520	0.00891	0.18867	0.01034	0.01262	65	0.16578	0.01397	0.01226	93	0.01759	1.30079	149.31	0.19534	0.32233
Thiamine-phosphate diphosphorylase	0.17520	0.00891	0.18867	0.01034	0.01262	65	0.16578	0.01397	0.01226	93	0.01759	1.30079	149.31	0.19534	0.32233
Uroporphyrinogen decarboxylase	0.17520	0.00891	0.18867	0.01034	0.01262	65	0.16578	0.01397	0.01226	93	0.01759	1.30079	149.31	0.19534	0.32233
Beta-fructofuranosidase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
Chorismate mutase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
Cu(+) exporting ATPase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
DNA topoisomerase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
Glucose-6-phosphate isomerase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
GMP synthase (glutamine-hydrolyzing)	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
L-lactate dehydrogenase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
Polyribonucleotide nucleotidyltransferase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
Tagatose-6-phosphate kinase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
Tagatose-bisphosphate aldolase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
Uridine kinase	0.15688	0.00436	0.16263	0.00226	0.00589	65	0.15286	0.00352	0.00615	93	0.00852	1.14607	153.07	0.25356	0.32233
(2E,6E)-farnesyl diphosphate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
(FADH(2)-oxidizing)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
[Acyl-carrier-protein] S-malonyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
1-acylglycerol-3-phosphate O-acyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
1-phosphofructokinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
1,4-alpha-glucan branching enzyme	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (cytidine(1402)-2’-O)-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (cytidine(1409)-2’-O)-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (cytosine(1402)-N(4))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (cytosine(967)-C(5))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (guanine(1207)-N(2))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (guanine(527)-N(7))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (guanine(966)-N(2))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
16S rRNA (uracil(1498)-N(3))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
2-hydroxymuconate tautomerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
2-iminobutanoate/2-iminopropanoate deaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
2-isopropylmalate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
23S rRNA (adenine(2503)-C(2))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
23S rRNA (cytidine(1920)-2’-O)-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
23S rRNA (cytosine(1962)-C(5))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
23S rRNA (guanine(745)-N(1))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
23S rRNA (guanosine(2251)-2’-O)-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
23S rRNA (uracil(1939)-C(5))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
23S rRNA pseudouridine(2605) synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
3’(2’),5’-bisphosphate nucleotidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
3-dehydroquinate dehydratase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
3-dehydroquinate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
3-hydroxyacyl-[acyl-carrier-protein] dehydratase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
3-isopropylmalate dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
3-phosphoshikimate 1-carboxyvinyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
4-alpha-glucanotransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
4-hydroxy-tetrahydrodipicolinate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
4-nitrophenylphosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
5-(carboxyamino)imidazole ribonucleotide mutase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
5-(carboxyamino)imidazole ribonucleotide synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
5-formyltetrahydrofolate cyclo-ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
5-methyltetrahydropteroyltriglutamate–homocysteine S-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
6-phospho-beta-galactosidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
6-phosphofructokinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
6-phosphogluconolactonase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Acetaldehyde dehydrogenase (acetylating)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Acetate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Acetolactate decarboxylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
acetylglucosaminyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Acylphosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Adenine phosphoribosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Adenosylhomocysteine nucleosidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Adenylate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Adenylosuccinate lyase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Adenylosuccinate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Alanine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Alanine racemase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Alanine transaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Aldose 1-epimerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Alpha-amylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Amidophosphoribosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Aminoacyl-tRNA hydrolase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Aminodeoxychorismate lyase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Aminodeoxychorismate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Anthranilate phosphoribosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Arginine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Asparaginase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Asparagine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Aspartate-semialdehyde dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Aspartate carbamoyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Aspartate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Beta-ketoacyl-[acyl-carrier-protein] synthase II	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Beta-ketoacyl-[acyl-carrier-protein] synthase III	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Beta-lactamase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Biotin–[acetyl-CoA-carboxylase] ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Biotin carboxylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Bleomycin hydrolase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Branched-chain-amino-acid transaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Calcium-transporting ATPase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Carbonate dehydratase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Catechol 2,3-dioxygenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
CCA tRNA nucleotidyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
CDP-diacylglycerol–glycerol-3-phosphate 3-phosphatidyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Chorismate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Coproporphyrinogen dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
CTP synthase (glutamine hydrolyzing)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Cystathionine beta-lyase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Cystathionine gamma-synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Cysteine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Cysteine synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Cytidine deaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
dCMP deaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Deoxyribose-phosphate aldolase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dephospho-CoA kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Diadenylate cyclase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Diaminopimelate decarboxylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydrofolate reductase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydrolipoyl dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydrolipoyllysine-residue acetyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydroneopterin aldolase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydroorotase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydroorotate dehydrogenase (NAD(+))	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydroorotate oxidase (fumarate)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydropteroate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dihydroxy-acid dehydratase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dimethylallyltranstransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
diphosphate specific)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Diphosphomevalonate decarboxylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
DNA-3-methyladenine glycosylase I	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
DNA-formamidopyrimidine glycosylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
DNA ligase (NAD(+))	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Dodecanoyl-[acyl-carrier-protein] hydrolase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
dTMP kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
dUTP diphosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Endopeptidase Clp	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Enoyl-[acyl-carrier-protein] reductase (NADH)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Exodeoxyribonuclease III	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Exodeoxyribonuclease V	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
FAD synthetase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Ferrochelatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Fructose-bisphosphate aldolase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Galactokinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Geranylgeranyl diphosphate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glucokinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glucosamine-1-phosphate N-acetyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glucosamine-6-phosphate deaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glucose-6-phosphate dehydrogenase (NAD(P)(+))	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glucose-6-phosphate dehydrogenase (NADP(+))	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutamate–ammonia ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutamate–tRNA(Gln) ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutamate-5-semialdehyde dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutamate 5-kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutamate racemase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutamine–fructose-6-phosphate transaminase (isomerizing)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutamyl aminopeptidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutathione-disulfide reductase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glutathione peroxidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glycerate 3-kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glycerol-3-phosphate dehydrogenase (NAD(P)(+))	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glycerol-3-phosphate oxidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glycerol kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glycerophosphodiester phosphodiesterase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Glycine hydroxymethyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
GMP reductase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
GTP cyclohydrolase I	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Guanylate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Histidine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Holo-[acyl-carrier-protein] synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Homoserine dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Homoserine kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Homoserine O-succinyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Hydroxymethylglutaryl-CoA reductase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Hydroxymethylglutaryl-CoA synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Hypoxanthine phosphoribosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
IMP cyclohydrolase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
IMP dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Indole-3-glycerol-phosphate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Inorganic diphosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Inositol-phosphate phosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Isoleucine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Isopentenyl-diphosphate Delta-isomerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Ketol-acid reductoisomerase (NADP(+))	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
L-threonylcarbamoyladenylate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Lactoylglutathione lyase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Leucine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Lipoate–protein ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Lysine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Magnesium-importing ATPase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Maltose 6’-phosphate phosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Maltose O-acetyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Mannose-6-phosphate isomerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Membrane alanyl aminopeptidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Methenyltetrahydrofolate cyclohydrolase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Methionine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Methionine adenosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Methionyl-tRNA formyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Methionyl aminopeptidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Methylated-DNA–[protein]-cysteine S-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Methylenetetrahydrofolate dehydrogenase (NADP(+))	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Methylenetetrahydrofolate reductase (NAD(P)H)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Mevalonate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Monosaccharide-transporting ATPase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
N-acetyldiaminopimelate deacetylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
N-acetylglucosamine-6-phosphate deacetylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
N-acetylneuraminate lyase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
N-acylglucosamine-6-phosphate 2-epimerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
NAD(+) kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
NAD(+) synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Neopullulanase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Nicotinamide-nucleotide amidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Nicotinate-nucleotide adenylyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Nicotinate phosphoribosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Non-specific serine/threonine protein kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
O-acetylhomoserine aminocarboxypropyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Oligonucleotidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Orotate phosphoribosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Orotidine-5’-phosphate decarboxylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Pantetheine-phosphate adenylyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Pantothenate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Peptidase Do	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Peptide chain release factor N(5)-glutamine methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Peptidoglycan glycosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Peroxiredoxin	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphate acetyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphatidate cytidylyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phospho-N-acetylmuramoyl-pentapeptide-transferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoenolpyruvate–protein phosphotransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoenolpyruvate carboxylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoglucosamine mutase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoglycerate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoglycolate phosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphomevalonate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphopantothenate–cysteine ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphopantothenoylcysteine decarboxylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphopentomutase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphopyruvate hydratase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoribosylamine–glycine ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoribosylaminoimidazolecarboxamide formyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoribosylaminoimidazolesuccinocarboxamide synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoribosylformylglycinamidine cyclo-ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoribosylformylglycinamidine synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoribosylglycinamide formyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Phosphoserine phosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Polyamine-transporting ATPase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Prephenate dehydratase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Prephenate dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Prepilin peptidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Proline–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Pyrimidine-nucleoside phosphorylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Pyrroline-5-carboxylate reductase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Pyruvate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Pyruvate oxidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Riboflavin kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Ribonuclease III	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Ribonuclease M5	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Ribonuclease P	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Ribonuclease Z	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Ribose-5-phosphate isomerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Ribulose-phosphate 3-epimerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
S-adenosylhomocysteine deaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
S-adenosylmethionine:tRNA ribosyltransferase-isomerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
S-methyl-5’-thioadenosine deaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
S-ribosylhomocysteine lyase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Selenocysteine lyase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Serine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Serine O-acetyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Shikimate dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Shikimate kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Signal peptidase II	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Starch synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Succinyl-diaminopimelate desuccinylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Superoxide dismutase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Tellurite methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Thiamine diphosphokinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Threonine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Threonine ammonia-lyase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Threonine synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Thymidine kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Thymidylate synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Trans-2-decenoyl-[acyl-carrier-protein] isomerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Triose-phosphate isomerase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Tripeptide aminopeptidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA-guanine(34) transglycosylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA (adenine(22)-N(1))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA (cytidine(34)-2’-O)-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA (guanine(37)-N(1))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA (guanine(46)-N(7))-methyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA dimethylallyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA pseudouridine(38-40) synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA pseudouridine(55) synthase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA(adenine(34)) deaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
tRNA(Ile)-lysidine synthetase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Tryptophan–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Tyrosine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-glucose–hexose-1-phosphate uridylyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-N-acetylglucosamine diphosphorylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-N-acetylmuramate–L-alanine ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-N-acetylmuramate dehydrogenase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-N-acetylmuramoyl-L-alanine–D-glutamate ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–L-lysine ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-N-acetylmuramoyl-tripeptide–D-alanyl-D-alanine ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UMP kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UMP/CMP kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Undecaprenol kinase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Uracil-DNA glycosylase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
UTP–glucose-1-phosphate uridylyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Valine–pyruvate transaminase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Valine–tRNA ligase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Xaa-Pro aminopeptidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Xaa-Pro dipeptidase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Xanthine phosphoribosyltransferase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
XTP/dITP diphosphatase	0.15679	0.00436	0.16254	0.00225	0.00589	65	0.15278	0.00352	0.00615	93	0.00851	1.14588	153.09	0.25363	0.32233
Pyruvate, water dikinase	0.13839	0.00777	0.13641	0.00758	0.01080	65	0.13978	0.01100	0.01088	93	0.01533	-0.21986	151.35	0.82627	0.84628
Alpha-L-fucosidase	0.08777	0.00445	0.09452	0.00260	0.00633	65	0.08306	0.00348	0.00612	93	0.00880	1.30152	148.96	0.19509	0.32233
DNA (cytosine-5-)-methyltransferase	0.08777	0.00445	0.09452	0.00260	0.00633	65	0.08306	0.00348	0.00612	93	0.00880	1.30152	148.96	0.19509	0.32233
(S,S)-butanediol dehydrogenase	0.08769	0.00445	0.09442	0.00259	0.00632	65	0.08298	0.00349	0.00612	93	0.00880	1.30129	149.14	0.19517	0.32233
Alpha-mannosidase	0.08769	0.00445	0.09442	0.00259	0.00632	65	0.08298	0.00349	0.00612	93	0.00880	1.30129	149.14	0.19517	0.32233
Diacetyl reductase ((S)-acetoin forming)	0.08769	0.00445	0.09442	0.00259	0.00632	65	0.08298	0.00349	0.00612	93	0.00880	1.30129	149.14	0.19517	0.32233
Diamine N-acetyltransferase	0.08769	0.00445	0.09442	0.00259	0.00632	65	0.08298	0.00349	0.00612	93	0.00880	1.30129	149.14	0.19517	0.32233
UDP-N-acetylglucosamine kinase	0.08769	0.00445	0.09442	0.00259	0.00632	65	0.08298	0.00349	0.00612	93	0.00880	1.30129	149.14	0.19517	0.32233
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
6-carboxytetrahydropterin synthase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
6-pyruvoyltetrahydropterin synthase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
7-carboxy-7-deazaguanine synthase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
7-cyano-7-deazaguanine synthase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Adenylate cyclase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Agmatine deiminase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Aminopyrimidine aminohydrolase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Arginine decarboxylase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Aspartate–ammonia ligase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Carboxynorspermidine decarboxylase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Cephalosporin-C deacetylase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Dolichyl-phosphate beta-D-mannosyltransferase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Fe(3+)-transporting ATPase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Glucan 1,6-alpha-glucosidase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Glycerone kinase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Hydroxymethylpyrimidine kinase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Lysine decarboxylase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
N-carbamoylputrescine amidase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Nucleoside-diphosphate kinase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Phosphomethylpyrimidine kinase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
PreQ(1) synthase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Pyroglutamyl-peptidase I	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Ribitol-5-phosphate 2-dehydrogenase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Saccharopine dehydrogenase (NAD(+), L-lysine-forming)	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Spermidine synthase	0.08760	0.00445	0.09433	0.00259	0.00631	65	0.08289	0.00349	0.00613	93	0.00879	1.30079	149.31	0.19534	0.32233
Lactocepin	0.06937	0.00389	0.06839	0.00189	0.00539	65	0.07006	0.00278	0.00546	93	0.00767	-0.21751	151.69	0.82810	0.84628
Acetylornithine transaminase	0.06928	0.00389	0.06829	0.00189	0.00539	65	0.06997	0.00276	0.00545	93	0.00767	-0.21872	151.52	0.82717	0.84628
Beta-N-acetylhexosaminidase	0.06928	0.00389	0.06829	0.00189	0.00539	65	0.06997	0.00276	0.00545	93	0.00767	-0.21872	151.52	0.82717	0.84628
(R,R)-butanediol dehydrogenase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
23S rRNA pseudouridine(746) synthase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
4-hydroxybenzoate polyprenyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
5’-nucleotidase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Acetylglutamate kinase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Aconitate hydratase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Alanine dehydrogenase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Alpha,alpha-phosphotrehalase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Amino-acid N-acetyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Arginine deiminase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Argininosuccinate lyase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Argininosuccinate synthase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
ATP phosphoribosyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Carbamate kinase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
CDP-diacylglycerol–serine O-phosphatidyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Citrate (Si)-synthase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Dextransucrase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Diacetyl reductase ((R)-acetoin forming)	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Diacylglycerol kinase (ATP)	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Diglucosyl diacylglycerol synthase (1,2-linking)	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Dipeptidase E	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
dTDP-4-dehydrorhamnose 3,5-epimerase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
dTDP-4-dehydrorhamnose reductase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
dTDP-glucose 4,6-dehydratase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Formimidoylglutamase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Formimidoyltetrahydrofolate cyclodeaminase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Fructan beta-fructosidase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Fructokinase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Glucose-1-phosphate thymidylyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Glutamate–cysteine ligase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Glutamate formimidoyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Glutamate N-acetyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Histidine ammonia-lyase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Histidinol-phosphatase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Histidinol-phosphate transaminase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Histidinol dehydrogenase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Imidazoleglycerol-phosphate dehydratase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Imidazolonepropionase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Isocitrate dehydrogenase (NADP(+))	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
isomerase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Kanamycin kinase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
N-acetyl-gamma-glutamyl-phosphate reductase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
N-acetylglucosaminephosphotransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
NAD(P)H dehydrogenase (quinone)	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Ornithine carbamoyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Phosphatidylglycerol–membrane-oligosaccharide glycerophosphotransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Phosphatidylserine decarboxylase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Phosphinothricin acetyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Phosphoribosyl-AMP cyclohydrolase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Phosphoribosyl-ATP diphosphatase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Poly(glycerol-phosphate) alpha-glucosyltransferase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Pyruvate, phosphate dikinase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
tRNA pseudouridine(32) synthase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
Urocanate hydratase	0.06919	0.00389	0.06820	0.00190	0.00540	65	0.06989	0.00275	0.00544	93	0.00766	-0.21986	151.35	0.82627	0.84628
2’,3’-cyclic-nucleotide 2’-phosphodiesterase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
3’-nucleotidase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
3-dehydro-L-gulonate-6-phosphate decarboxylase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Alpha-galactosidase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Epoxyqueuosine reductase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Fructose-bisphosphatase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Glycerol dehydrogenase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Homocysteine S-methyltransferase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
L-ribulose-5-phosphate 4-epimerase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Phosphoenolpyruvate carboxykinase (ATP)	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Phosphoglycerate dehydrogenase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Phosphoserine transaminase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
Sucrose phosphorylase	0.06911	0.00388	0.06811	0.00190	0.00541	65	0.06980	0.00274	0.00543	93	0.00766	-0.22095	151.17	0.82543	0.84628
2-dehydropantoate 2-reductase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
4-carboxymuconolactone decarboxylase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
Aspartate racemase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
Fructose-6-phosphate phosphoketolase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
Hydroxyacylglutathione hydrolase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
L-threonine aldolase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
Malate dehydrogenase (oxaloacetate-decarboxylating)	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
Phosphoketolase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
Quaternary-amine-transporting ATPase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
Sorbitol-6-phosphate 2-dehydrogenase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944
UDP-galactopyranose mutase	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00008	0.00000	0.00008	93	0.00012	0.06352	145.13	0.94944	0.94944

plot.dat <- tb.ra %>%
  arrange(desc(`Overall Mean`)) %>%
  slice_head(n=50)%>%
  mutate(
    description = fct_reorder(description, `Overall Mean`),
    description = factor(description, levels = levels(description), ordered=T)
  ) %>%
  arrange(description) %>%
  mutate(
    id = 1:n(),
    step = ifelse(id%%2 == 0, 1, 0),
    Mean_diff = `Tumor Mean` - `Non-Tumor Mean`,
    diff_se = SEpooled,
    Mean_diff_ll = Mean_diff - qt(0.975, df)*diff_se,
    Mean_diff_ul = Mean_diff + qt(0.975, df)*diff_se
  ) %>%
  pivot_longer(
    cols=contains("Mean"),
    names_to = "group",
    values_to = "mean"
  )



p1.d <- plot.dat %>%
  filter(group %in% c("Tumor Mean","Non-Tumor Mean")) %>%
  mutate(
    group = ifelse(group == "Tumor Mean", "Tumor", "Non-Tumor"),
    col = ifelse(step == 1, "grey90", "white"),
    h=1, w=Inf
    
  )
p1 <- ggplot()+
  geom_tile(data = p1.d,
              aes(y = description, x=0,
                  height=h, width=w),
              fill = p1.d$col, color=p1.d$col)+
    geom_bar(data=p1.d,
             aes(x=mean, y=description,
                 group=group, color=group,
                 fill=group),
             stat="identity",position = "dodge",
             alpha = 1)+
    labs(x="Mean RelAbundance")+
    theme_classic()+
    theme(
      legend.position = "bottom",
      plot.margin = unit(c(1,0,1,1), "lines")
    )

p2.d <- plot.dat %>%
  filter(group %in% c("Mean_diff", "Mean_diff_ll", "Mean_diff_ul")) %>%
  pivot_wider(
    names_from = group,
    values_from = mean
  ) %>%
  mutate(
    group = ifelse(Mean_diff > 0, "Tumor", "Non-Tumor"),
    p = sprintf("%.3f", round(fdr_p,3)),
    ll = min(Mean_diff_ll)-0.01,
    ul = max(Mean_diff_ul)+0.01
  )
p2<-ggplot(p2.d, aes(x=Mean_diff, y=description))+
    geom_tile(data = p1.d,
              aes(y = description, x=0,
                  height=h, width=w),
              fill = p1.d$col, color=p1.d$col)+
    geom_vline(xintercept = 0, linetype="dashed", alpha=0.5)+
    geom_segment(aes(x=Mean_diff_ll, y=description, xend=Mean_diff_ul, yend=description))+
    geom_point(aes(fill=group, color=group))+
    geom_text(aes(label=p, x=unique(ul)+0.04))+
    coord_cartesian(xlim = c(unique(p2.d$ll), unique(p2.d$ul)),
                    clip = 'off') +
    annotate("text", x=unique(p2.d$ul)+0.08,y = 25,
             angle=90,
             label="q-value (FDR Corrected p-value)")+
    labs(x="Mean Difference in RelAbundance")+
    theme_classic()+
    theme(
      legend.position = "bottom",
      axis.title.y = element_blank(),
      axis.text.y = element_blank(),
      axis.line.y = element_blank(),
      axis.ticks.y = element_blank(),
      plot.margin = unit(c(1,4,1,0), "lines")
    )

# plot
p <- p1 + p2 +
  plot_annotation(title="Stratefied EC Data - Streptococcus sanguinis : 50 most abundant descriptions")
p

ggsave("output/updated-figures-2021-05-20/picrust-strepto-EC.pdf",p,units="in", height=12, width=10)

Modeling Difference between Tumor and Non-Tumor

For the modeling, we used a generalized linear mixed model (GLMM).

First, we looked at the biserial correlation between the abundance of each description and the tumor status.

tb <- mydata %>%
  group_by(description)%>%
  summarise(
    r = cor(tumor, Abundance)
  ) %>%
  mutate(
    M=mean(r)
  )

ggplot(tb, aes(x=r))+
  geom_density()+
  geom_vline(aes(xintercept = M))+
  labs(x="Biserial Correlation",title="Relationship between description abundance and tumor (tumor vs. non-tumor)")+
  theme(panel.grid = element_blank())

Next, we need the data to be on an interpretable scale. First, let’s use the raw abundance like scale.

p <- ggplot(mydata, aes(x=Abundance))+
  geom_density()
p

mydata <- mydata %>%
  mutate(Abundance.dich=ifelse(Abundance==0, 0, 1))
table(mydata$Abundance.dich)


    0     1 
11460 69436

Let’s first run models by description so that we can avoid the nesting issue initially. We will come back to this to conduct the final model (it will be more powerful).

DESCRIPTIONS <- unique(mydata$description)
i<-1
dat0 <- mydata %>% filter(description==DESCRIPTIONS[i])

# quasipossion (approximately negative binom) give an approx. answer.
fit0 <- glm(
  Abundance ~ 1 + tumor,
  data= dat0,
  family=quasipoisson(link = "log")
)
summary(fit0)


Call:
glm(formula = Abundance ~ 1 + tumor, family = quasipoisson(link = "log"), 
    data = dat0)

Deviance Residuals: 
   Min      1Q  Median      3Q     Max  
 -9.27   -7.88   -3.43    3.93   16.52  

Coefficients:
            Estimate Std. Error t value Pr(>|t|)    
(Intercept)    3.759      0.118   31.92   <2e-16 ***
tumor         -0.126      0.191   -0.66     0.51    
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

(Dispersion parameter for quasipoisson family taken to be 55.387)

    Null deviance: 8252.3  on 157  degrees of freedom
Residual deviance: 8227.9  on 156  degrees of freedom
AIC: NA

Number of Fisher Scoring iterations: 6

Run over all descriptors

results.out <- as.data.frame(matrix(ncol=4, nrow=length(DESCRIPTIONS)))
colnames(results.out) <- c("description", "Est", "SE", "p")
#results.out$description <-DESCRIPTIONS

i <- 1
for(i in 1:length(DESCRIPTIONS)){
#for(i in 1:5){ 
  dat0 <- mydata %>%
    filter(description == DESCRIPTIONS[i])
  fit0 <- glm(
  Abundance ~ 1 + tumor,
  data= dat0,
  family=quasipoisson(link = "log")
)
  fit.sum <- summary(fit0)
  results.out[i, 1] <- DESCRIPTIONS[i]
  results.out[i, 2:4] <- fit.sum$coefficients[2, c(1,2,4)]
}

results.out$fdr_p <- p.adjust(results.out$p, method="fdr")

kable(results.out, format="html", digits=3) %>%
  kable_styling(full_width = T)%>%
  scroll_box(width="100%", height="600px")

description	Est	SE	p	fdr_p
(2E,6E)-farnesyl diphosphate synthase	-0.126	0.191	0.509	0.560
(FADH(2)-oxidizing)	-0.126	0.191	0.509	0.560
(R)-2-methylmalate dehydratase	-0.126	0.191	0.509	0.560
(R,R)-butanediol dehydrogenase	-0.133	0.217	0.540	0.560
(S,S)-butanediol dehydrogenase	-0.121	0.201	0.547	0.560
[Acyl-carrier-protein] S-malonyltransferase	-0.126	0.191	0.509	0.560
[Formate-C-acetyltransferase]-activating enzyme	-0.127	0.192	0.509	0.560
1-acylglycerol-3-phosphate O-acyltransferase	-0.126	0.191	0.509	0.560
1-phosphofructokinase	-0.126	0.191	0.509	0.560
1,4-alpha-glucan branching enzyme	-0.126	0.191	0.509	0.560
16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase	-0.126	0.191	0.509	0.560
16S rRNA (cytidine(1402)-2’-O)-methyltransferase	-0.126	0.191	0.509	0.560
16S rRNA (cytidine(1409)-2’-O)-methyltransferase	-0.126	0.191	0.509	0.560
16S rRNA (cytosine(1402)-N(4))-methyltransferase	-0.126	0.191	0.509	0.560
16S rRNA (cytosine(967)-C(5))-methyltransferase	-0.126	0.191	0.509	0.560
16S rRNA (guanine(1207)-N(2))-methyltransferase	-0.126	0.191	0.509	0.560
16S rRNA (guanine(527)-N(7))-methyltransferase	-0.126	0.191	0.509	0.560
16S rRNA (guanine(966)-N(2))-methyltransferase	-0.126	0.191	0.509	0.560
16S rRNA (uracil(1498)-N(3))-methyltransferase	-0.126	0.191	0.509	0.560
16S rRNA pseudouridine(516) synthase	-0.126	0.191	0.509	0.560
2’,3’-cyclic-nucleotide 2’-phosphodiesterase	-0.133	0.217	0.541	0.560
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase	-0.126	0.191	0.509	0.560
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-0.121	0.201	0.548	0.560
2-dehydropantoate 2-reductase	-0.335	1.544	0.829	0.829
2-hydroxymuconate tautomerase	-0.126	0.191	0.509	0.560
2-iminobutanoate/2-iminopropanoate deaminase	-0.126	0.191	0.509	0.560
2-isopropylmalate synthase	-0.126	0.191	0.509	0.560
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-0.126	0.191	0.509	0.560
23S rRNA (adenine(2503)-C(2))-methyltransferase	-0.126	0.191	0.509	0.560
23S rRNA (cytidine(1920)-2’-O)-methyltransferase	-0.126	0.191	0.509	0.560
23S rRNA (cytosine(1962)-C(5))-methyltransferase	-0.126	0.191	0.509	0.560
23S rRNA (guanine(745)-N(1))-methyltransferase	-0.126	0.191	0.509	0.560
23S rRNA (guanosine(2251)-2’-O)-methyltransferase	-0.126	0.191	0.509	0.560
23S rRNA (pseudouridine(1915)-N(3))-methyltransferase	-0.126	0.191	0.509	0.560
23S rRNA (uracil(1939)-C(5))-methyltransferase	-0.126	0.191	0.509	0.560
23S rRNA pseudouridine(1911/1915/1917) synthase	-0.126	0.191	0.509	0.560
23S rRNA pseudouridine(2605) synthase	-0.126	0.191	0.509	0.560
23S rRNA pseudouridine(746) synthase	-0.133	0.217	0.540	0.560
3’-nucleotidase	-0.133	0.217	0.541	0.560
3’(2’),5’-bisphosphate nucleotidase	-0.126	0.191	0.509	0.560
3-dehydro-L-gulonate-6-phosphate decarboxylase	-0.133	0.217	0.541	0.560
3-dehydroquinate dehydratase	-0.126	0.191	0.509	0.560
3-dehydroquinate synthase	-0.126	0.191	0.509	0.560
3-deoxy-7-phosphoheptulonate synthase	-0.126	0.191	0.510	0.560
3-hydroxyacyl-[acyl-carrier-protein] dehydratase	-0.126	0.191	0.509	0.560
3-isopropylmalate dehydratase	-0.126	0.191	0.509	0.560
3-isopropylmalate dehydrogenase	-0.126	0.191	0.509	0.560
3-oxoacyl-[acyl-carrier-protein] reductase	-0.126	0.191	0.509	0.560
3-phosphoshikimate 1-carboxyvinyltransferase	-0.126	0.191	0.509	0.560
4-alpha-glucanotransferase	-0.126	0.191	0.509	0.560
4-carboxymuconolactone decarboxylase	-0.335	1.544	0.829	0.829
4-hydroxy-tetrahydrodipicolinate reductase	-0.128	0.194	0.510	0.560
4-hydroxy-tetrahydrodipicolinate synthase	-0.126	0.191	0.509	0.560
4-hydroxybenzoate polyprenyltransferase	-0.133	0.217	0.540	0.560
4-nitrophenylphosphatase	-0.126	0.191	0.509	0.560
5’-nucleotidase	-0.133	0.217	0.540	0.560
5-(carboxyamino)imidazole ribonucleotide mutase	-0.126	0.191	0.509	0.560
5-(carboxyamino)imidazole ribonucleotide synthase	-0.126	0.191	0.509	0.560
5-formyltetrahydrofolate cyclo-ligase	-0.126	0.191	0.509	0.560
5-methyltetrahydropteroyltriglutamate–homocysteine S-methyltransferase	-0.126	0.191	0.509	0.560
6-carboxytetrahydropterin synthase	-0.121	0.201	0.548	0.560
6-phospho-beta-galactosidase	-0.126	0.191	0.509	0.560
6-phospho-beta-glucosidase	-0.129	0.198	0.514	0.560
6-phosphofructokinase	-0.126	0.191	0.509	0.560
6-phosphogluconolactonase	-0.126	0.191	0.509	0.560
6-pyruvoyltetrahydropterin synthase	-0.121	0.201	0.548	0.560
7-carboxy-7-deazaguanine synthase	-0.121	0.201	0.548	0.560
7-cyano-7-deazaguanine synthase	-0.121	0.201	0.548	0.560
8-oxo-dGTP diphosphatase	-0.128	0.194	0.510	0.560
Acetaldehyde dehydrogenase (acetylating)	-0.126	0.191	0.509	0.560
Acetate kinase	-0.126	0.191	0.509	0.560
Acetolactate decarboxylase	-0.126	0.191	0.509	0.560
Acetolactate synthase	-0.126	0.191	0.509	0.560
Acetyl-CoA carboxylase	-0.126	0.191	0.509	0.560
acetylglucosaminyltransferase	-0.126	0.191	0.509	0.560
Acetylglutamate kinase	-0.133	0.217	0.540	0.560
Acetylornithine transaminase	-0.133	0.217	0.539	0.560
Aconitate hydratase	-0.133	0.217	0.540	0.560
Acylphosphatase	-0.126	0.191	0.509	0.560
Adenine phosphoribosyltransferase	-0.126	0.191	0.509	0.560
Adenosylhomocysteine nucleosidase	-0.126	0.191	0.509	0.560
Adenylate cyclase	-0.121	0.201	0.548	0.560
Adenylate kinase	-0.126	0.191	0.509	0.560
Adenylosuccinate lyase	-0.126	0.191	0.509	0.560
Adenylosuccinate synthase	-0.126	0.191	0.509	0.560
ADP-ribose diphosphatase	-0.128	0.194	0.510	0.560
Agmatine deiminase	-0.121	0.201	0.548	0.560
Alanine–tRNA ligase	-0.126	0.191	0.509	0.560
Alanine dehydrogenase	-0.133	0.217	0.540	0.560
Alanine racemase	-0.126	0.191	0.509	0.560
Alanine transaminase	-0.126	0.191	0.509	0.560
Alcohol dehydrogenase	-0.127	0.192	0.509	0.560
Aldose 1-epimerase	-0.126	0.191	0.509	0.560
Alpha-amylase	-0.126	0.191	0.509	0.560
Alpha-galactosidase	-0.133	0.217	0.541	0.560
Alpha-L-fucosidase	-0.121	0.200	0.546	0.560
Alpha-mannosidase	-0.121	0.201	0.547	0.560
Alpha,alpha-phosphotrehalase	-0.133	0.217	0.540	0.560
Amidophosphoribosyltransferase	-0.126	0.191	0.509	0.560
Amino-acid N-acetyltransferase	-0.133	0.217	0.540	0.560
Aminoacyl-tRNA hydrolase	-0.126	0.191	0.509	0.560
Aminodeoxychorismate lyase	-0.126	0.191	0.509	0.560
Aminodeoxychorismate synthase	-0.126	0.191	0.509	0.560
Aminopyrimidine aminohydrolase	-0.121	0.201	0.548	0.560
Anthranilate phosphoribosyltransferase	-0.126	0.191	0.509	0.560
Anthranilate synthase	-0.126	0.191	0.509	0.560
Arginine–tRNA ligase	-0.126	0.191	0.509	0.560
Arginine decarboxylase	-0.121	0.201	0.548	0.560
Arginine deiminase	-0.133	0.217	0.540	0.560
Argininosuccinate lyase	-0.133	0.217	0.540	0.560
Argininosuccinate synthase	-0.133	0.217	0.540	0.560
Arsenate reductase (glutaredoxin)	-0.128	0.194	0.510	0.560
Asparaginase	-0.126	0.191	0.509	0.560
Asparagine–tRNA ligase	-0.126	0.191	0.509	0.560
Asparaginyl-tRNA synthase (glutamine-hydrolyzing)	-0.126	0.191	0.509	0.560
Aspartate–ammonia ligase	-0.121	0.201	0.548	0.560
Aspartate–tRNA ligase	-0.128	0.194	0.510	0.560
Aspartate-semialdehyde dehydrogenase	-0.126	0.191	0.509	0.560
Aspartate carbamoyltransferase	-0.126	0.191	0.509	0.560
Aspartate kinase	-0.126	0.191	0.509	0.560
Aspartate racemase	-0.335	1.544	0.829	0.829
ATP phosphoribosyltransferase	-0.133	0.217	0.540	0.560
Beta-fructofuranosidase	-0.126	0.191	0.509	0.560
Beta-galactosidase	-0.128	0.194	0.510	0.560
Beta-ketoacyl-[acyl-carrier-protein] synthase II	-0.126	0.191	0.509	0.560
Beta-ketoacyl-[acyl-carrier-protein] synthase III	-0.126	0.191	0.509	0.560
Beta-lactamase	-0.126	0.191	0.509	0.560
Beta-N-acetylhexosaminidase	-0.133	0.217	0.539	0.560
Biotin–[acetyl-CoA-carboxylase] ligase	-0.126	0.191	0.509	0.560
Biotin carboxylase	-0.126	0.191	0.509	0.560
Bleomycin hydrolase	-0.126	0.191	0.509	0.560
Branched-chain-amino-acid transaminase	-0.126	0.191	0.509	0.560
Calcium-transporting ATPase	-0.126	0.191	0.509	0.560
Carbamate kinase	-0.133	0.217	0.540	0.560
Carbamoyl-phosphate synthase (glutamine-hydrolyzing)	-0.126	0.191	0.509	0.560
Carbonate dehydratase	-0.126	0.191	0.509	0.560
Carboxynorspermidine decarboxylase	-0.121	0.201	0.548	0.560
Catechol 2,3-dioxygenase	-0.126	0.191	0.509	0.560
CCA tRNA nucleotidyltransferase	-0.126	0.191	0.509	0.560
CDP-diacylglycerol–glycerol-3-phosphate 3-phosphatidyltransferase	-0.126	0.191	0.509	0.560
CDP-diacylglycerol–serine O-phosphatidyltransferase	-0.133	0.217	0.540	0.560
Cephalosporin-C deacetylase	-0.121	0.201	0.548	0.560
Chorismate mutase	-0.126	0.191	0.509	0.560
Chorismate synthase	-0.126	0.191	0.509	0.560
Citrate (Si)-synthase	-0.133	0.217	0.540	0.560
Coproporphyrinogen dehydrogenase	-0.126	0.191	0.509	0.560
CTP synthase (glutamine hydrolyzing)	-0.126	0.191	0.509	0.560
Cu(+) exporting ATPase	-0.126	0.191	0.509	0.560
Cystathionine beta-lyase	-0.126	0.191	0.509	0.560
Cystathionine gamma-synthase	-0.126	0.191	0.509	0.560
Cysteine–tRNA ligase	-0.126	0.191	0.509	0.560
Cysteine desulfurase	-0.126	0.191	0.509	0.560
Cysteine synthase	-0.126	0.191	0.509	0.560
Cytidine deaminase	-0.126	0.191	0.509	0.560
D-alanine–D-alanine ligase	-0.124	0.191	0.517	0.560
D-alanine–poly(phosphoribitol) ligase	-0.126	0.191	0.509	0.560
dCMP deaminase	-0.126	0.191	0.509	0.560
Deoxyribose-phosphate aldolase	-0.126	0.191	0.509	0.560
Dephospho-CoA kinase	-0.126	0.191	0.509	0.560
Dextransucrase	-0.133	0.217	0.540	0.560
Diacetyl reductase ((R)-acetoin forming)	-0.133	0.217	0.540	0.560
Diacetyl reductase ((S)-acetoin forming)	-0.121	0.201	0.547	0.560
Diacylglycerol kinase (ATP)	-0.133	0.217	0.540	0.560
Diadenylate cyclase	-0.126	0.191	0.509	0.560
Diamine N-acetyltransferase	-0.121	0.201	0.547	0.560
Diaminopimelate decarboxylase	-0.126	0.191	0.509	0.560
Diglucosyl diacylglycerol synthase (1,2-linking)	-0.133	0.217	0.540	0.560
Dihydrofolate reductase	-0.126	0.191	0.509	0.560
Dihydrofolate synthase	-0.126	0.191	0.509	0.560
Dihydrolipoyl dehydrogenase	-0.126	0.191	0.509	0.560
Dihydrolipoyllysine-residue acetyltransferase	-0.126	0.191	0.509	0.560
Dihydroneopterin aldolase	-0.126	0.191	0.509	0.560
Dihydroorotase	-0.126	0.191	0.509	0.560
Dihydroorotate dehydrogenase (NAD(+))	-0.126	0.191	0.509	0.560
Dihydroorotate oxidase (fumarate)	-0.126	0.191	0.509	0.560
Dihydropteroate synthase	-0.126	0.191	0.509	0.560
Dihydroxy-acid dehydratase	-0.126	0.191	0.509	0.560
Dimethylallyltranstransferase	-0.126	0.191	0.509	0.560
Dipeptidase E	-0.133	0.217	0.540	0.560
diphosphate specific)	-0.126	0.191	0.509	0.560
Diphosphomevalonate decarboxylase	-0.126	0.191	0.509	0.560
DNA-(apurinic or apyrimidinic site) lyase	-0.126	0.191	0.509	0.560
DNA-3-methyladenine glycosylase I	-0.126	0.191	0.509	0.560
DNA-directed DNA polymerase	-0.126	0.191	0.509	0.560
DNA-directed RNA polymerase	-0.126	0.191	0.509	0.560
DNA-formamidopyrimidine glycosylase	-0.126	0.191	0.509	0.560
DNA (cytosine-5-)-methyltransferase	-0.121	0.200	0.546	0.560
DNA helicase	-0.126	0.191	0.509	0.560
DNA ligase (NAD(+))	-0.126	0.191	0.509	0.560
DNA topoisomerase	-0.126	0.191	0.509	0.560
DNA topoisomerase (ATP-hydrolyzing)	-0.126	0.191	0.509	0.560
Dodecanoyl-[acyl-carrier-protein] hydrolase	-0.126	0.191	0.509	0.560
Dolichyl-phosphate beta-D-mannosyltransferase	-0.121	0.201	0.548	0.560
dTDP-4-dehydrorhamnose 3,5-epimerase	-0.133	0.217	0.540	0.560
dTDP-4-dehydrorhamnose reductase	-0.133	0.217	0.540	0.560
dTDP-glucose 4,6-dehydratase	-0.133	0.217	0.540	0.560
dTMP kinase	-0.126	0.191	0.509	0.560
dUTP diphosphatase	-0.126	0.191	0.509	0.560
Endopeptidase Clp	-0.126	0.191	0.509	0.560
Enoyl-[acyl-carrier-protein] reductase (NADH)	-0.126	0.191	0.509	0.560
Epoxyqueuosine reductase	-0.133	0.217	0.541	0.560
Exo-alpha-sialidase	-0.121	0.201	0.548	0.560
Exodeoxyribonuclease III	-0.126	0.191	0.509	0.560
Exodeoxyribonuclease V	-0.126	0.191	0.509	0.560
Exodeoxyribonuclease VII	-0.126	0.191	0.509	0.560
FAD synthetase	-0.126	0.191	0.509	0.560
Fe(3+)-transporting ATPase	-0.121	0.201	0.548	0.560
Ferrochelatase	-0.126	0.191	0.509	0.560
Formate–tetrahydrofolate ligase	-0.128	0.194	0.510	0.560
Formate C-acetyltransferase	-0.128	0.194	0.510	0.560
Formimidoylglutamase	-0.133	0.217	0.540	0.560
Formimidoyltetrahydrofolate cyclodeaminase	-0.133	0.217	0.540	0.560
Fructan beta-fructosidase	-0.133	0.217	0.540	0.560
Fructokinase	-0.133	0.217	0.540	0.560
Fructose-6-phosphate phosphoketolase	-0.335	1.544	0.829	0.829
Fructose-bisphosphatase	-0.133	0.217	0.541	0.560
Fructose-bisphosphate aldolase	-0.126	0.191	0.509	0.560
Galactokinase	-0.126	0.191	0.509	0.560
Galactose-6-phosphate isomerase	-0.124	0.191	0.517	0.560
Geranylgeranyl diphosphate synthase	-0.126	0.191	0.509	0.560
Glucan 1,6-alpha-glucosidase	-0.121	0.201	0.548	0.560
Glucokinase	-0.126	0.191	0.509	0.560
Glucosamine-1-phosphate N-acetyltransferase	-0.126	0.191	0.509	0.560
Glucosamine-6-phosphate deaminase	-0.126	0.191	0.509	0.560
Glucose-1-phosphate adenylyltransferase	-0.126	0.191	0.509	0.560
Glucose-1-phosphate thymidylyltransferase	-0.133	0.217	0.540	0.560
Glucose-6-phosphate dehydrogenase (NAD(P)(+))	-0.126	0.191	0.509	0.560
Glucose-6-phosphate dehydrogenase (NADP(+))	-0.126	0.191	0.509	0.560
Glucose-6-phosphate isomerase	-0.126	0.191	0.509	0.560
Glutamate–ammonia ligase	-0.126	0.191	0.509	0.560
Glutamate–cysteine ligase	-0.133	0.217	0.540	0.560
Glutamate–tRNA(Gln) ligase	-0.126	0.191	0.509	0.560
Glutamate-5-semialdehyde dehydrogenase	-0.126	0.191	0.509	0.560
Glutamate 5-kinase	-0.126	0.191	0.509	0.560
Glutamate dehydrogenase (NADP(+))	-0.128	0.194	0.510	0.560
Glutamate formimidoyltransferase	-0.133	0.217	0.540	0.560
Glutamate N-acetyltransferase	-0.133	0.217	0.540	0.560
Glutamate racemase	-0.126	0.191	0.509	0.560
Glutamine–fructose-6-phosphate transaminase (isomerizing)	-0.126	0.191	0.509	0.560
Glutaminyl-tRNA synthase (glutamine-hydrolyzing)	-0.126	0.191	0.509	0.560
Glutamyl aminopeptidase	-0.126	0.191	0.509	0.560
Glutathione-disulfide reductase	-0.126	0.191	0.509	0.560
Glutathione peroxidase	-0.126	0.191	0.509	0.560
Glyceraldehyde-3-phosphate dehydrogenase (NADP(+))	-0.133	0.217	0.541	0.560
Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)	-0.126	0.191	0.509	0.560
Glycerate 3-kinase	-0.126	0.191	0.509	0.560
Glycerol-3-phosphate 1-O-acyltransferase	-0.126	0.191	0.509	0.560
Glycerol-3-phosphate dehydrogenase (NAD(P)(+))	-0.126	0.191	0.509	0.560
Glycerol-3-phosphate oxidase	-0.126	0.191	0.509	0.560
Glycerol dehydrogenase	-0.133	0.217	0.541	0.560
Glycerol kinase	-0.126	0.191	0.509	0.560
Glycerone kinase	-0.121	0.201	0.548	0.560
Glycerophosphodiester phosphodiesterase	-0.126	0.191	0.509	0.560
Glycine–tRNA ligase	-0.126	0.191	0.509	0.560
Glycine hydroxymethyltransferase	-0.126	0.191	0.509	0.560
Glycogen phosphorylase	-0.128	0.194	0.510	0.560
GMP reductase	-0.126	0.191	0.509	0.560
GMP synthase (glutamine-hydrolyzing)	-0.126	0.191	0.509	0.560
GTP cyclohydrolase I	-0.126	0.191	0.509	0.560
GTP diphosphokinase	-0.126	0.191	0.509	0.560
Guanylate kinase	-0.126	0.191	0.509	0.560
H(+)-transporting two-sector ATPase	-0.127	0.192	0.509	0.560
Histidine–tRNA ligase	-0.126	0.191	0.509	0.560
Histidine ammonia-lyase	-0.133	0.217	0.540	0.560
Histidine kinase	-0.126	0.191	0.510	0.560
Histidinol-phosphatase	-0.133	0.217	0.540	0.560
Histidinol-phosphate transaminase	-0.133	0.217	0.540	0.560
Histidinol dehydrogenase	-0.133	0.217	0.540	0.560
Holo-[acyl-carrier-protein] synthase	-0.126	0.191	0.509	0.560
Homocysteine S-methyltransferase	-0.133	0.217	0.541	0.560
Homoserine dehydrogenase	-0.126	0.191	0.509	0.560
Homoserine kinase	-0.126	0.191	0.509	0.560
Homoserine O-succinyltransferase	-0.126	0.191	0.509	0.560
Hydroxyacylglutathione hydrolase	-0.335	1.544	0.829	0.829
Hydroxyethylthiazole kinase	-0.121	0.201	0.548	0.560
Hydroxymethylglutaryl-CoA reductase	-0.126	0.191	0.509	0.560
Hydroxymethylglutaryl-CoA synthase	-0.126	0.191	0.509	0.560
Hydroxymethylpyrimidine kinase	-0.121	0.201	0.548	0.560
Hypoxanthine phosphoribosyltransferase	-0.126	0.191	0.509	0.560
Imidazoleglycerol-phosphate dehydratase	-0.133	0.217	0.540	0.560
Imidazolonepropionase	-0.133	0.217	0.540	0.560
IMP cyclohydrolase	-0.126	0.191	0.509	0.560
IMP dehydrogenase	-0.126	0.191	0.509	0.560
Indole-3-glycerol-phosphate synthase	-0.126	0.191	0.509	0.560
Inorganic diphosphatase	-0.126	0.191	0.509	0.560
Inositol-phosphate phosphatase	-0.126	0.191	0.509	0.560
Iron-chelate-transporting ATPase	-0.126	0.191	0.509	0.560
Isocitrate dehydrogenase (NADP(+))	-0.133	0.217	0.540	0.560
Isoleucine–tRNA ligase	-0.126	0.191	0.509	0.560
isomerase	-0.133	0.217	0.540	0.560
Isopentenyl-diphosphate Delta-isomerase	-0.126	0.191	0.509	0.560
Kanamycin kinase	-0.133	0.217	0.540	0.560
Ketol-acid reductoisomerase (NADP(+))	-0.126	0.191	0.509	0.560
L-lactate dehydrogenase	-0.126	0.191	0.509	0.560
L-ribulose-5-phosphate 4-epimerase	-0.133	0.217	0.541	0.560
L-serine ammonia-lyase	-0.126	0.191	0.509	0.560
L-threonine aldolase	-0.335	1.544	0.829	0.829
L-threonylcarbamoyladenylate synthase	-0.126	0.191	0.509	0.560
Lactocepin	-0.134	0.217	0.538	0.560
Lactoylglutathione lyase	-0.126	0.191	0.509	0.560
Leucine–tRNA ligase	-0.126	0.191	0.509	0.560
Lipoate–protein ligase	-0.126	0.191	0.509	0.560
Lysine–tRNA ligase	-0.126	0.191	0.509	0.560
Lysine decarboxylase	-0.121	0.201	0.548	0.560
Magnesium-importing ATPase	-0.126	0.191	0.509	0.560
Malate dehydrogenase (oxaloacetate-decarboxylating)	-0.335	1.544	0.829	0.829
Maltose 6’-phosphate phosphatase	-0.126	0.191	0.509	0.560
Maltose O-acetyltransferase	-0.126	0.191	0.509	0.560
Mannose-6-phosphate isomerase	-0.126	0.191	0.509	0.560
Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-0.121	0.201	0.548	0.560
Membrane alanyl aminopeptidase	-0.126	0.191	0.509	0.560
Methenyltetrahydrofolate cyclohydrolase	-0.126	0.191	0.509	0.560
Methionine–tRNA ligase	-0.126	0.191	0.509	0.560
Methionine adenosyltransferase	-0.126	0.191	0.509	0.560
Methionyl-tRNA formyltransferase	-0.126	0.191	0.509	0.560
Methionyl aminopeptidase	-0.126	0.191	0.509	0.560
Methylated-DNA–[protein]-cysteine S-methyltransferase	-0.126	0.191	0.509	0.560
Methylenetetrahydrofolate dehydrogenase (NADP(+))	-0.126	0.191	0.509	0.560
Methylenetetrahydrofolate reductase (NAD(P)H)	-0.126	0.191	0.509	0.560
Mevalonate kinase	-0.126	0.191	0.509	0.560
Monosaccharide-transporting ATPase	-0.126	0.191	0.509	0.560
N-acetyl-gamma-glutamyl-phosphate reductase	-0.133	0.217	0.540	0.560
N-acetyldiaminopimelate deacetylase	-0.126	0.191	0.509	0.560
N-acetylglucosamine-6-phosphate deacetylase	-0.126	0.191	0.509	0.560
N-acetylglucosaminephosphotransferase	-0.133	0.217	0.540	0.560
N-acetylneuraminate lyase	-0.126	0.191	0.509	0.560
N-acylglucosamine-6-phosphate 2-epimerase	-0.126	0.191	0.509	0.560
N-carbamoylputrescine amidase	-0.121	0.201	0.548	0.560
N(6)-L-threonylcarbamoyladenine synthase	-0.128	0.194	0.510	0.560
NAD(+) kinase	-0.126	0.191	0.509	0.560
NAD(+) synthase	-0.126	0.191	0.509	0.560
NAD(P)H dehydrogenase (quinone)	-0.133	0.217	0.540	0.560
Neopullulanase	-0.126	0.191	0.509	0.560
Nicotinamide-nucleotide amidase	-0.126	0.191	0.509	0.560
Nicotinate-nucleotide adenylyltransferase	-0.126	0.191	0.509	0.560
Nicotinate phosphoribosyltransferase	-0.126	0.191	0.509	0.560
Non-specific serine/threonine protein kinase	-0.126	0.191	0.509	0.560
Nucleoside-diphosphate kinase	-0.121	0.201	0.548	0.560
O-acetylhomoserine aminocarboxypropyltransferase	-0.126	0.191	0.509	0.560
Oligonucleotidase	-0.126	0.191	0.509	0.560
Ornithine carbamoyltransferase	-0.133	0.217	0.540	0.560
Orotate phosphoribosyltransferase	-0.126	0.191	0.509	0.560
Orotidine-5’-phosphate decarboxylase	-0.126	0.191	0.509	0.560
Pantetheine-phosphate adenylyltransferase	-0.126	0.191	0.509	0.560
Pantothenate kinase	-0.126	0.191	0.509	0.560
Peptidase Do	-0.126	0.191	0.509	0.560
Peptide-methionine (R)-S-oxide reductase	-0.126	0.191	0.509	0.560
Peptide-methionine (S)-S-oxide reductase	-0.126	0.191	0.509	0.560
Peptide chain release factor N(5)-glutamine methyltransferase	-0.126	0.191	0.509	0.560
Peptide deformylase	-0.126	0.191	0.509	0.560
Peptidoglycan glycosyltransferase	-0.126	0.191	0.509	0.560
Peptidylprolyl isomerase	-0.126	0.191	0.509	0.560
Peroxiredoxin	-0.126	0.191	0.509	0.560
Phenylalanine–tRNA ligase	-0.126	0.191	0.509	0.560
Phosphate-transporting ATPase	-0.125	0.191	0.513	0.560
Phosphate acetyltransferase	-0.126	0.191	0.509	0.560
Phosphatidate cytidylyltransferase	-0.126	0.191	0.509	0.560
Phosphatidylglycerol–membrane-oligosaccharide glycerophosphotransferase	-0.133	0.217	0.540	0.560
Phosphatidylserine decarboxylase	-0.133	0.217	0.540	0.560
Phosphinothricin acetyltransferase	-0.133	0.217	0.540	0.560
Phospho-N-acetylmuramoyl-pentapeptide-transferase	-0.126	0.191	0.509	0.560
Phosphoenolpyruvate–protein phosphotransferase	-0.126	0.191	0.509	0.560
Phosphoenolpyruvate carboxykinase (ATP)	-0.133	0.217	0.541	0.560
Phosphoenolpyruvate carboxylase	-0.126	0.191	0.509	0.560
Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)	-0.126	0.191	0.509	0.560
Phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating)	-0.126	0.191	0.509	0.560
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating)	-0.126	0.191	0.509	0.560
Phosphoglucosamine mutase	-0.126	0.191	0.509	0.560
Phosphoglycerate dehydrogenase	-0.133	0.217	0.541	0.560
Phosphoglycerate kinase	-0.126	0.191	0.509	0.560
Phosphoglycerate mutase (2,3-diphosphoglycerate-dependent)	-0.126	0.191	0.509	0.560
Phosphoglycerate mutase (2,3-diphosphoglycerate-independent)	-0.129	0.196	0.512	0.560
Phosphoglycolate phosphatase	-0.126	0.191	0.509	0.560
Phosphoketolase	-0.335	1.544	0.829	0.829
Phosphomethylpyrimidine kinase	-0.121	0.201	0.548	0.560
Phosphomevalonate kinase	-0.126	0.191	0.509	0.560
Phosphopantothenate–cysteine ligase	-0.126	0.191	0.509	0.560
Phosphopantothenoylcysteine decarboxylase	-0.126	0.191	0.509	0.560
Phosphopentomutase	-0.126	0.191	0.509	0.560
Phosphopyruvate hydratase	-0.126	0.191	0.509	0.560
Phosphoribosyl-AMP cyclohydrolase	-0.133	0.217	0.540	0.560
Phosphoribosyl-ATP diphosphatase	-0.133	0.217	0.540	0.560
Phosphoribosylamine–glycine ligase	-0.126	0.191	0.509	0.560
Phosphoribosylaminoimidazolecarboxamide formyltransferase	-0.126	0.191	0.509	0.560
Phosphoribosylaminoimidazolesuccinocarboxamide synthase	-0.126	0.191	0.509	0.560
Phosphoribosylanthranilate isomerase	-0.126	0.191	0.509	0.560
Phosphoribosylformylglycinamidine cyclo-ligase	-0.126	0.191	0.509	0.560
Phosphoribosylformylglycinamidine synthase	-0.126	0.191	0.509	0.560
Phosphoribosylglycinamide formyltransferase	-0.126	0.191	0.509	0.560
Phosphoserine phosphatase	-0.126	0.191	0.509	0.560
Phosphoserine transaminase	-0.133	0.217	0.541	0.560
Polar-amino-acid-transporting ATPase	-0.125	0.191	0.514	0.560
Poly(glycerol-phosphate) alpha-glucosyltransferase	-0.133	0.217	0.540	0.560
Polyamine-transporting ATPase	-0.126	0.191	0.509	0.560
Polyribonucleotide nucleotidyltransferase	-0.126	0.191	0.509	0.560
Prephenate dehydratase	-0.126	0.191	0.509	0.560
Prephenate dehydrogenase	-0.126	0.191	0.509	0.560
Prepilin peptidase	-0.126	0.191	0.509	0.560
PreQ(1) synthase	-0.121	0.201	0.548	0.560
Proline–tRNA ligase	-0.126	0.191	0.509	0.560
Protein-N(pi)-phosphohistidine–sugar phosphotransferase	-0.126	0.191	0.509	0.560
Protein-serine/threonine phosphatase	-0.126	0.191	0.509	0.560
Protein-tyrosine-phosphatase	-0.128	0.194	0.510	0.560
Pullulanase	-0.129	0.198	0.514	0.560
Purine-nucleoside phosphorylase	-0.126	0.191	0.509	0.560
Pyridoxal 5’-phosphate synthase (glutamine hydrolyzing)	-0.121	0.201	0.548	0.560
Pyridoxal kinase	-0.128	0.194	0.510	0.560
Pyrimidine-nucleoside phosphorylase	-0.126	0.191	0.509	0.560
Pyroglutamyl-peptidase I	-0.121	0.201	0.548	0.560
Pyrroline-5-carboxylate reductase	-0.126	0.191	0.509	0.560
Pyruvate dehydrogenase (acetyl-transferring)	-0.126	0.191	0.509	0.560
Pyruvate kinase	-0.126	0.191	0.509	0.560
Pyruvate oxidase	-0.126	0.191	0.509	0.560
Pyruvate, phosphate dikinase	-0.133	0.217	0.540	0.560
Pyruvate, water dikinase	-0.133	0.217	0.540	0.560
Quaternary-amine-transporting ATPase	-0.335	1.544	0.829	0.829
Ribitol-5-phosphate 2-dehydrogenase	-0.121	0.201	0.548	0.560
Riboflavin kinase	-0.126	0.191	0.509	0.560
Ribonuclease H	-0.125	0.191	0.513	0.560
Ribonuclease III	-0.126	0.191	0.509	0.560
Ribonuclease M5	-0.126	0.191	0.509	0.560
Ribonuclease P	-0.126	0.191	0.509	0.560
Ribonuclease Z	-0.126	0.191	0.509	0.560
Ribonucleoside-diphosphate reductase	-0.126	0.191	0.509	0.560
Ribonucleoside-triphosphate reductase	-0.126	0.191	0.509	0.560
Ribose-5-phosphate isomerase	-0.126	0.191	0.509	0.560
Ribose-phosphate diphosphokinase	-0.126	0.191	0.509	0.560
Ribosomal-protein-alanine N-acetyltransferase	-0.128	0.194	0.510	0.560
Ribulose-phosphate 3-epimerase	-0.126	0.191	0.509	0.560
RNA helicase	-0.126	0.191	0.509	0.560
S-adenosylhomocysteine deaminase	-0.126	0.191	0.509	0.560
S-adenosylmethionine:tRNA ribosyltransferase-isomerase	-0.126	0.191	0.509	0.560
S-methyl-5’-thioadenosine deaminase	-0.126	0.191	0.509	0.560
S-ribosylhomocysteine lyase	-0.126	0.191	0.509	0.560
Saccharopine dehydrogenase (NAD(+), L-lysine-forming)	-0.121	0.201	0.548	0.560
Selenocysteine lyase	-0.126	0.191	0.509	0.560
Serine–tRNA ligase	-0.126	0.191	0.509	0.560
Serine-type D-Ala-D-Ala carboxypeptidase	-0.128	0.194	0.510	0.560
Serine O-acetyltransferase	-0.126	0.191	0.509	0.560
Shikimate dehydrogenase	-0.126	0.191	0.509	0.560
Shikimate kinase	-0.126	0.191	0.509	0.560
Signal peptidase I	-0.128	0.194	0.510	0.560
Signal peptidase II	-0.126	0.191	0.509	0.560
Site-specific DNA-methyltransferase (adenine-specific)	-0.128	0.194	0.511	0.560
Sorbitol-6-phosphate 2-dehydrogenase	-0.335	1.544	0.829	0.829
Sortase A	-0.129	0.198	0.514	0.560
Spermidine synthase	-0.121	0.201	0.548	0.560
Starch synthase	-0.126	0.191	0.509	0.560
Succinyl-diaminopimelate desuccinylase	-0.126	0.191	0.509	0.560
Sucrose phosphorylase	-0.133	0.217	0.541	0.560
Superoxide dismutase	-0.126	0.191	0.509	0.560
Tagatose-6-phosphate kinase	-0.126	0.191	0.509	0.560
Tagatose-bisphosphate aldolase	-0.126	0.191	0.509	0.560
Tellurite methyltransferase	-0.126	0.191	0.509	0.560
Tetrahydrofolate synthase	-0.126	0.191	0.509	0.560
Thiamine-phosphate diphosphorylase	-0.121	0.201	0.548	0.560
Thiamine diphosphokinase	-0.126	0.191	0.509	0.560
Thioredoxin-disulfide reductase	-0.126	0.191	0.509	0.560
Threonine–tRNA ligase	-0.126	0.191	0.509	0.560
Threonine ammonia-lyase	-0.126	0.191	0.509	0.560
Threonine synthase	-0.126	0.191	0.509	0.560
Thymidine kinase	-0.126	0.191	0.509	0.560
Thymidylate synthase	-0.126	0.191	0.509	0.560
Trans-2-decenoyl-[acyl-carrier-protein] isomerase	-0.126	0.191	0.509	0.560
Transketolase	-0.123	0.193	0.524	0.560
Triose-phosphate isomerase	-0.126	0.191	0.509	0.560
Tripeptide aminopeptidase	-0.126	0.191	0.509	0.560
tRNA-guanine(34) transglycosylase	-0.126	0.191	0.509	0.560
tRNA (adenine(22)-N(1))-methyltransferase	-0.126	0.191	0.509	0.560
tRNA (cytidine(34)-2’-O)-methyltransferase	-0.126	0.191	0.509	0.560
tRNA (guanine(37)-N(1))-methyltransferase	-0.126	0.191	0.509	0.560
tRNA (guanine(46)-N(7))-methyltransferase	-0.126	0.191	0.509	0.560
tRNA dimethylallyltransferase	-0.126	0.191	0.509	0.560
tRNA pseudouridine(32) synthase	-0.133	0.217	0.540	0.560
tRNA pseudouridine(38-40) synthase	-0.126	0.191	0.509	0.560
tRNA pseudouridine(55) synthase	-0.126	0.191	0.509	0.560
tRNA(adenine(34)) deaminase	-0.126	0.191	0.509	0.560
tRNA(Ile)-lysidine synthetase	-0.126	0.191	0.509	0.560
Tryptophan–tRNA ligase	-0.126	0.191	0.509	0.560
Tryptophan synthase	-0.126	0.191	0.509	0.560
Type I site-specific deoxyribonuclease	-0.128	0.193	0.509	0.560
Tyrosine–tRNA ligase	-0.126	0.191	0.509	0.560
UDP-galactopyranose mutase	-0.335	1.544	0.829	0.829
UDP-glucose–hexose-1-phosphate uridylyltransferase	-0.126	0.191	0.509	0.560
UDP-glucose 4-epimerase	-0.126	0.191	0.509	0.560
UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-0.126	0.191	0.509	0.560
UDP-N-acetylglucosamine diphosphorylase	-0.126	0.191	0.509	0.560
UDP-N-acetylglucosamine kinase	-0.121	0.201	0.547	0.560
UDP-N-acetylmuramate–L-alanine ligase	-0.126	0.191	0.509	0.560
UDP-N-acetylmuramate dehydrogenase	-0.126	0.191	0.509	0.560
UDP-N-acetylmuramoyl-L-alanine–D-glutamate ligase	-0.126	0.191	0.509	0.560
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase	-0.126	0.191	0.509	0.560
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–L-lysine ligase	-0.126	0.191	0.509	0.560
UDP-N-acetylmuramoyl-tripeptide–D-alanyl-D-alanine ligase	-0.126	0.191	0.509	0.560
UDP-N-acetylmuramoylpentapeptide-lysine N(6)-alanyltransferase	-0.126	0.191	0.509	0.560
UMP kinase	-0.126	0.191	0.509	0.560
UMP/CMP kinase	-0.126	0.191	0.509	0.560
Undecaprenol kinase	-0.126	0.191	0.509	0.560
Undecaprenyl-diphosphate phosphatase	-0.126	0.191	0.509	0.560
Uracil-DNA glycosylase	-0.126	0.191	0.509	0.560
Uracil phosphoribosyltransferase	-0.126	0.191	0.509	0.560
Uridine kinase	-0.126	0.191	0.509	0.560
Urocanate hydratase	-0.133	0.217	0.540	0.560
Uroporphyrinogen decarboxylase	-0.121	0.201	0.548	0.560
UTP–glucose-1-phosphate uridylyltransferase	-0.126	0.191	0.509	0.560
Valine–pyruvate transaminase	-0.126	0.191	0.509	0.560
Valine–tRNA ligase	-0.126	0.191	0.509	0.560
Xaa-Pro aminopeptidase	-0.126	0.191	0.509	0.560
Xaa-Pro dipeptidase	-0.126	0.191	0.509	0.560
Xaa-Pro dipeptidyl-peptidase	-0.128	0.194	0.510	0.560
Xanthine phosphoribosyltransferase	-0.126	0.191	0.509	0.560
XTP/dITP diphosphatase	-0.126	0.191	0.509	0.560

# merge with tb.ra for full results table
full.res <- left_join(tb.ra, results.out, by = "description")

write.csv(full.res, "output/picrust_ec_stratefied_strepto_data_results.csv", row.names = F)

Part 2 KO Data

descriptions <- readr::read_tsv("data/PICRUST/ko_pred_metagenome_unstrat_descrip.tsv")[,1:2] %>%
  distinct()


-- Column specification --------------------------------------------------------
cols(
  .default = col_double(),
  `function` = col_character(),
  description = col_character()
)
i Use `spec()` for the full column specifications.

colnames(descriptions) <- c("func", "description")

pi.dat <- readxl::read_xlsx("data/PICRUST-Stratified/KO_strepto.xlsx")
colnames(pi.dat) <- c("func",  colnames(pi.dat)[-c(1)])

# add descriptions to dataframe
pi.dat <- left_join(pi.dat, descriptions, by="func")
pi.dat <- pi.dat[,c(1,161,3:160)]

# aggregate descriptions to get 1 description per row - unique;y defined.
pi.dat <- pi.dat %>%
  group_by(description) %>%
  summarise(across(`X1.S37.Jun172016`:`X99.D01.S37.Jun232016`,.fns = sum))

# make long format
pi.dat <- pi.dat %>%
  pivot_longer(
    cols=`X1.S37.Jun172016`:`X99.D01.S37.Jun232016`,
    names_to = "ID",
    values_to = "Abundance"
  ) %>%
  mutate(
    ID = substr(ID, 2, 99)
  )

d <- as.data.frame(dat.16s)
mydata <- full_join(pi.dat, d)

Joining, by = "ID"

Warning in class(x) <- c(setdiff(subclass, tibble_class), tibble_class): Setting
class(x) to multiple strings ("tbl_df", "tbl", ...); result will no longer be an
S4 object

mydata <- mydata %>%
  mutate(
    ID.n = as.numeric(as.factor(ID)),
    description.n = as.numeric(as.factor(description))
  ) %>%
  group_by(ID) %>%
  mutate(
    dem = ifelse(sum(Abundance)==0, 1, sum(Abundance)),
    RelAbundance = Abundance/dem*100) %>%
  ungroup()%>%
  group_by(description)%>%
  mutate(avgRA = mean(RelAbundance))

Abundance

# Run on all descriptions
tb.ra1 <- mydata %>%
  group_by(description) %>%
  summarise(ng = n(),
            Overall.M = mean(RelAbundance),
            Overall.SE = sd(RelAbundance)/sqrt(ng))
tb.ra2m <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(M = mean(RelAbundance)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = M)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2se <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n(),SE = sd(RelAbundance)/sqrt(ng)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = SE)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2var <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n(), VAR = var(RelAbundance)) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = VAR)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra2ng <- mydata %>%
  group_by(description, tumor.cat) %>%
  summarise(ng=n()) %>%
  pivot_wider(id_cols = description,
              names_from = tumor.cat,
              values_from = ng)

`summarise()` has grouped output by 'description'. You can override using the `.groups` argument.

tb.ra <- left_join(tb.ra1, tb.ra2m)

Joining, by = "description"

tb.ra <- cbind(tb.ra, tb.ra2se[,-1])
tb.ra <- cbind(tb.ra, tb.ra2var[,-1])
tb.ra <- cbind(tb.ra, tb.ra2ng[,-1]) 

colnames(tb.ra) <- c("description", "ng", "Overall Mean", "Overall SE", "Non-Tumor Mean", "Tumor Mean", "Non-Tumor SE", "Tumor SE","Non-Tumor Var", "Tumor Var", "Non-Tumor Ng", "Tumor Ng")
tb.ra <- tb.ra %>%
  arrange(desc(`Overall Mean`))
tb.ra <- tb.ra[, c("description", "Overall Mean", "Overall SE","Tumor Mean","Tumor Var", "Tumor SE","Tumor Ng", "Non-Tumor Mean","Non-Tumor Var", "Non-Tumor SE", "Non-Tumor Ng")]

# compute t-test
tb.ra <- tb.ra %>%
  mutate(
    SEpooled = sqrt(`Tumor Var`/`Tumor Ng` + `Non-Tumor Var`/`Non-Tumor Ng`),
    t = (`Tumor Mean` - `Non-Tumor Mean`)/(SEpooled),
    df = ((`Tumor Var`/`Tumor Ng` + `Non-Tumor Var`/`Non-Tumor Ng`)**2)/(((`Tumor Var`/`Tumor Ng`)**2)/(`Tumor Ng`-1) + ((`Non-Tumor Var`/`Non-Tumor Ng`)**2)/(`Non-Tumor Ng`-1)),
    p = pt(q = abs(t), df=df, lower.tail = F)*2,
    fdr_p = p.adjust(p, method="fdr")
  )



kable(tb.ra, format="html", digits=5, caption="Stratefied KO Data - Streptococcus sanguinis : Average RelAbundance of Each Description (sorted in descending order)") %>%
  kable_styling(full_width = T) %>%
  scroll_box(width = "100%", height="600px")

Stratefied KO Data - Streptococcus sanguinis : Average RelAbundance of Each Description (sorted in descending order)
description	Overall Mean	Overall SE	Tumor Mean	Tumor Var	Tumor SE	Tumor Ng	Non-Tumor Mean	Non-Tumor Var	Non-Tumor SE	Non-Tumor Ng	SEpooled	t	df	p	fdr_p
ABC-2.A; ABC-2 type transport system ATP-binding protein	0.78266	0.02171	0.81063	0.05576	0.02929	65	0.76310	0.08741	0.03066	93	0.04240	1.12102	153.16	0.26403	0.32890
ABC-2.P; ABC-2 type transport system permease protein	0.78266	0.02171	0.81063	0.05576	0.02929	65	0.76310	0.08741	0.03066	93	0.04240	1.12102	153.16	0.26403	0.32890
SPP; sucrose-6-phosphatase [EC:3.1.3.24]	0.69566	0.01945	0.71691	0.04439	0.02613	65	0.68080	0.07061	0.02756	93	0.03798	0.95080	153.46	0.34320	0.42642
ABC.CD.A; putative ABC transport system ATP-binding protein	0.66958	0.01875	0.69532	0.04186	0.02538	65	0.65159	0.06486	0.02641	93	0.03662	1.19409	152.92	0.23429	0.32890
ABC.CD.P; putative ABC transport system permease protein	0.58263	0.01618	0.60165	0.03076	0.02176	65	0.56933	0.04871	0.02289	93	0.03158	1.02333	153.37	0.30776	0.38282
K07052; uncharacterized protein	0.51314	0.01443	0.53329	0.02487	0.01956	65	0.49905	0.03837	0.02031	93	0.02820	1.21393	152.82	0.22665	0.32890
ABCB-BAC; ATP-binding cassette, subfamily B, bacterial	0.49563	0.01450	0.50792	0.02468	0.01949	65	0.48703	0.03935	0.02057	93	0.02833	0.73733	153.51	0.46205	0.57282
mutT, NUDT15, MTH2; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]	0.45208	0.01411	0.46102	0.02352	0.01902	65	0.44584	0.03720	0.02000	93	0.02760	0.54987	153.35	0.58321	0.69865
oppA, mppA; oligopeptide transport system substrate-binding protein	0.37403	0.01398	0.39643	0.02485	0.01955	65	0.35837	0.03479	0.01934	93	0.02750	1.38402	150.37	0.16840	0.32890
ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:3.6.3.21]	0.32180	0.00977	0.33691	0.01169	0.01341	65	0.31123	0.01731	0.01364	93	0.01913	1.34237	151.87	0.18148	0.32890
ABC.PA.P; polar amino acid transport system permease protein	0.32180	0.00977	0.33691	0.01169	0.01341	65	0.31123	0.01731	0.01364	93	0.01913	1.34237	151.87	0.18148	0.32890
ABC.PA.S; polar amino acid transport system substrate-binding protein	0.32180	0.00977	0.33691	0.01169	0.01341	65	0.31123	0.01731	0.01364	93	0.01913	1.34237	151.87	0.18148	0.32890
K07729; putative transcriptional regulator	0.30433	0.00900	0.31160	0.00951	0.01210	65	0.29925	0.01515	0.01276	93	0.01758	0.70191	153.49	0.48380	0.59911
ecfT; energy-coupling factor transport system permease protein	0.27834	0.00801	0.29010	0.00773	0.01091	65	0.27012	0.01174	0.01124	93	0.01566	1.27551	152.47	0.20407	0.32890
gpmB; probable phosphoglycerate mutase [EC:5.4.2.12]	0.26083	0.00877	0.26473	0.00918	0.01188	65	0.25810	0.01434	0.01242	93	0.01719	0.38584	153.11	0.70015	0.83385
E5.3.1.26, lacA, lacB; galactose-6-phosphate isomerase [EC:5.3.1.26]	0.24362	0.00778	0.25594	0.00753	0.01076	65	0.23501	0.01092	0.01084	93	0.01527	1.37087	151.35	0.17245	0.32890
lacI, galR; LacI family transcriptional regulator	0.23488	0.00652	0.24328	0.00502	0.00879	65	0.22902	0.00787	0.00920	93	0.01273	1.12103	153.16	0.26403	0.32890
argR, ahrC; transcriptional regulator of arginine metabolism	0.23480	0.00651	0.24319	0.00502	0.00879	65	0.22893	0.00787	0.00920	93	0.01272	1.12102	153.16	0.26403	0.32890
PTS-Man-EIIB, manX; PTS system, mannose-specific IIB component [EC:2.7.1.191]	0.23480	0.00651	0.24319	0.00502	0.00879	65	0.22893	0.00787	0.00920	93	0.01272	1.12102	153.16	0.26403	0.32890
PTS-Man-EIIC, manY; PTS system, mannose-specific IIC component	0.23480	0.00651	0.24319	0.00502	0.00879	65	0.22893	0.00787	0.00920	93	0.01272	1.12102	153.16	0.26403	0.32890
rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]	0.23480	0.00651	0.24319	0.00502	0.00879	65	0.22893	0.00787	0.00920	93	0.01272	1.12102	153.16	0.26403	0.32890
agrA, blpR, fsrA; two-component system, LytTR family, response regulator AgrA	0.20876	0.00806	0.22165	0.00828	0.01129	65	0.19976	0.01153	0.01114	93	0.01586	1.38024	150.21	0.16956	0.32890
ABCC-BAC; ATP-binding cassette, subfamily C, bacterial	0.20012	0.00591	0.20908	0.00425	0.00809	65	0.19386	0.00636	0.00827	93	0.01157	1.31589	152.12	0.19019	0.32890
ecfA2; energy-coupling factor transport system ATP-binding protein [EC:3.6.3.-]	0.20012	0.00591	0.20908	0.00425	0.00809	65	0.19386	0.00636	0.00827	93	0.01157	1.31589	152.12	0.19019	0.32890
ABC.PE.S; peptide/nickel transport system substrate-binding protein	0.20003	0.00591	0.20899	0.00425	0.00808	65	0.19377	0.00636	0.00827	93	0.01156	1.31592	152.16	0.19018	0.32890
pstB; phosphate transport system ATP-binding protein [EC:3.6.3.27]	0.20003	0.00591	0.20899	0.00425	0.00808	65	0.19377	0.00636	0.00827	93	0.01156	1.31592	152.16	0.19018	0.32890
ABC.FEV.P; iron complex transport system permease protein	0.19999	0.00591	0.20894	0.00424	0.00808	65	0.19373	0.00636	0.00827	93	0.01156	1.31587	152.18	0.19020	0.32890
hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]	0.19121	0.00551	0.19624	0.00356	0.00741	65	0.18770	0.00568	0.00781	93	0.01077	0.79348	153.49	0.42872	0.53209
yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]	0.16531	0.00593	0.17483	0.00446	0.00828	65	0.15865	0.00628	0.00822	93	0.01167	1.38662	150.54	0.16761	0.32890
ABC.MS.S; multiple sugar transport system substrate-binding protein	0.16526	0.00593	0.17479	0.00445	0.00828	65	0.15861	0.00628	0.00822	93	0.01167	1.38656	150.59	0.16763	0.32890
agrC, blpH, fsrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]	0.16526	0.00593	0.17479	0.00445	0.00828	65	0.15861	0.00628	0.00822	93	0.01167	1.38656	150.59	0.16763	0.32890
E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]	0.16522	0.00593	0.17474	0.00445	0.00827	65	0.15857	0.00629	0.00822	93	0.01166	1.38646	150.63	0.16765	0.32890
ssb; single-strand DNA-binding protein	0.15658	0.00434	0.16217	0.00223	0.00586	65	0.15266	0.00350	0.00613	93	0.00848	1.12104	153.16	0.26403	0.32890
ABC.FEV.A; iron complex transport system ATP-binding protein [EC:3.6.3.34]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
ABC.SS.P; simple sugar transport system permease protein	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
acpP; acyl carrier protein	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
ccdA; cytochrome c-type biogenesis protein	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
crcB, FEX; fluoride exporter	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
E4.3.1.17, sdaA, sdaB, tdcG; L-serine dehydratase [EC:4.3.1.17]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
GLPF; glycerol uptake facilitator protein	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
iscS, NFS1; cysteine desulfurase [EC:2.8.1.7]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
PDF, def; peptide deformylase [EC:3.5.1.88]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
PTS-Man-EIID, manZ; PTS system, mannose-specific IID component	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
rnj; ribonuclease J [EC:3.1.-.-]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
rtpR; ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
secA; preprotein translocase subunit SecA	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
secY; preprotein translocase subunit SecY	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
trkA, ktrA; trk system potassium uptake protein	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
trkH, trkG, ktrB; trk system potassium uptake protein	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
trpB; tryptophan synthase beta chain [EC:4.2.1.20]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9]	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
yidC, spoIIIJ, OXA1, ccfA; YidC/Oxa1 family membrane protein insertase	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
znuA; zinc transport system substrate-binding protein	0.15653	0.00434	0.16213	0.00223	0.00586	65	0.15262	0.00350	0.00613	93	0.00848	1.12102	153.16	0.26403	0.32890
E2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]	0.15649	0.00434	0.16208	0.00223	0.00586	65	0.15258	0.00349	0.00613	93	0.00848	1.12095	153.17	0.26406	0.32890
K07010; putative glutamine amidotransferase	0.15649	0.00434	0.16208	0.00223	0.00586	65	0.15258	0.00349	0.00613	93	0.00848	1.12095	153.17	0.26406	0.32890
spxA; regulatory protein spx	0.15649	0.00434	0.16208	0.00223	0.00586	65	0.15258	0.00349	0.00613	93	0.00848	1.12095	153.17	0.26406	0.32890
ABC.GLN1.P; putative glutamine transport system permease protein	0.15644	0.00434	0.16204	0.00223	0.00585	65	0.15254	0.00349	0.00613	93	0.00848	1.12082	153.17	0.26412	0.32890
E3.2.1.86B, bglA; 6-phospho-beta-glucosidase [EC:3.2.1.86]	0.14780	0.00529	0.14947	0.00336	0.00719	65	0.14663	0.00520	0.00748	93	0.01038	0.27335	152.88	0.78495	0.83385
K07025; putative hydrolase of the HAD superfamily	0.14780	0.00529	0.14947	0.00336	0.00719	65	0.14663	0.00520	0.00748	93	0.01038	0.27335	152.88	0.78495	0.83385
pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]	0.14780	0.00529	0.14947	0.00336	0.00719	65	0.14663	0.00520	0.00748	93	0.01038	0.27335	152.88	0.78495	0.83385
pulA; pullulanase [EC:3.2.1.41]	0.14775	0.00529	0.14942	0.00337	0.00720	65	0.14659	0.00520	0.00748	93	0.01038	0.27312	152.84	0.78513	0.83385
K07491; putative transposase	0.13050	0.00658	0.14058	0.00564	0.00932	65	0.12345	0.00763	0.00906	93	0.01300	1.31839	149.34	0.18939	0.32890
ABC.X4.A; putative ABC transport system ATP-binding protein	0.12181	0.00389	0.12797	0.00188	0.00538	65	0.11750	0.00273	0.00542	93	0.00764	1.37087	151.35	0.17245	0.32890
ABC.X4.P; putative ABC transport system permease protein	0.12181	0.00389	0.12797	0.00188	0.00538	65	0.11750	0.00273	0.00542	93	0.00764	1.37087	151.35	0.17245	0.32890
yesN; two-component system, response regulator YesN	0.12181	0.00389	0.12797	0.00188	0.00538	65	0.11750	0.00273	0.00542	93	0.00764	1.37087	151.35	0.17245	0.32890
ABC.FEV.S; iron complex transport system substrate-binding protein	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
ABC.X4.S; putative ABC transport system substrate-binding protein	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
comE; two-component system, LytTR family, response regulator ComE	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
comX1_2; competence protein ComX	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
K07007; uncharacterized protein	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
K17318, lplA; putative aldouronate transport system substrate-binding protein	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
lplB; putative aldouronate transport system permease protein	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
lplC; putative aldouronate transport system permease protein	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
metI; D-methionine transport system permease protein	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
padR; PadR family transcriptional regulator, regulatory protein PadR	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
rnhB; ribonuclease HII [EC:3.1.26.4]	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
zmpB; zinc metalloprotease ZmpB [EC:3.4.24.-]	0.12177	0.00389	0.12792	0.00188	0.00538	65	0.11746	0.00273	0.00542	93	0.00763	1.37084	151.40	0.17245	0.32890
ABC.MS.P; multiple sugar transport system permease protein	0.12172	0.00389	0.12788	0.00188	0.00537	65	0.11742	0.00273	0.00542	93	0.00763	1.37073	151.45	0.17249	0.32890
ABC.MS.P1; multiple sugar transport system permease protein	0.12172	0.00389	0.12788	0.00188	0.00537	65	0.11742	0.00273	0.00542	93	0.00763	1.37073	151.45	0.17249	0.32890
tcyM; L-cystine transport system permease protein	0.12172	0.00389	0.12788	0.00188	0.00537	65	0.11742	0.00273	0.00542	93	0.00763	1.37073	151.45	0.17249	0.32890
RP-L33, MRPL33, rpmG; large subunit ribosomal protein L33	0.11308	0.00353	0.11531	0.00147	0.00475	65	0.11151	0.00233	0.00501	93	0.00690	0.55015	153.39	0.58302	0.69865
ABC.CD.TX; HlyD family secretion protein	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
ARSC1, arsC; arsenate reductase [EC:1.20.4.1]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
fhs; formate–tetrahydrofolate ligase [EC:6.3.4.3]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
ftsK, spoIIIE; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
KAE1, tsaD, QRI7; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
lepB; signal peptidase I [EC:3.4.21.89]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
nrdI; protein involved in ribonucleotide reduction	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
nudF; ADP-ribose pyrophosphatase [EC:3.6.1.13]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
pdxK, pdxY; pyridoxine kinase [EC:2.7.1.35]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
sufB; Fe-S cluster assembly protein SufB	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
thiJ; protein deglycase [EC:3.5.1.124]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
trxA; thioredoxin 1	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]	0.11303	0.00353	0.11527	0.00147	0.00476	65	0.11147	0.00233	0.00500	93	0.00690	0.54993	153.36	0.58317	0.69865
E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]	0.11299	0.00353	0.11522	0.00147	0.00476	65	0.11143	0.00232	0.00500	93	0.00690	0.54966	153.32	0.58335	0.69865
E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]	0.11299	0.00353	0.11522	0.00147	0.00476	65	0.11143	0.00232	0.00500	93	0.00690	0.54966	153.32	0.58335	0.69865
msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein	0.11299	0.00353	0.11522	0.00147	0.00476	65	0.11143	0.00232	0.00500	93	0.00690	0.54966	153.32	0.58335	0.69865
pflA, pflC, pflE; pyruvate formate lyase activating enzyme [EC:1.97.1.4]	0.11299	0.00353	0.11522	0.00147	0.00476	65	0.11143	0.00232	0.00500	93	0.00690	0.54966	153.32	0.58335	0.69865
srtA; sortase A [EC:3.4.22.70]	0.11299	0.00353	0.11522	0.00147	0.00476	65	0.11143	0.00232	0.00500	93	0.00690	0.54966	153.32	0.58335	0.69865
hsdM; type I restriction enzyme M protein [EC:2.1.1.72]	0.11294	0.00352	0.11517	0.00147	0.00476	65	0.11139	0.00232	0.00499	93	0.00690	0.54935	153.27	0.58356	0.69865
hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]	0.11294	0.00352	0.11517	0.00147	0.00476	65	0.11139	0.00232	0.00499	93	0.00690	0.54935	153.27	0.58356	0.69865
hemE, UROD; uroporphyrinogen decarboxylase [EC:4.1.1.37]	0.08700	0.00439	0.09372	0.00251	0.00621	65	0.08230	0.00339	0.00604	93	0.00866	1.31839	149.34	0.18939	0.32890
licD; lipopolysaccharide cholinephosphotransferase [EC:2.7.8.-]	0.08700	0.00439	0.09372	0.00251	0.00621	65	0.08230	0.00339	0.00604	93	0.00866	1.31839	149.34	0.18939	0.32890
NEU1; sialidase-1 [EC:3.2.1.18]	0.08700	0.00439	0.09372	0.00251	0.00621	65	0.08230	0.00339	0.00604	93	0.00866	1.31839	149.34	0.18939	0.32890
thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]	0.08700	0.00439	0.09372	0.00251	0.00621	65	0.08230	0.00339	0.00604	93	0.00866	1.31839	149.34	0.18939	0.32890
thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]	0.08700	0.00439	0.09372	0.00251	0.00621	65	0.08230	0.00339	0.00604	93	0.00866	1.31839	149.34	0.18939	0.32890
ABC-2.CYL.A, cylA; multidrug/hemolysin transport system ATP-binding protein	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
ABC-2.CYL.P, cylB; multidrug/hemolysin transport system permease protein	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
clpC; ATP-dependent Clp protease ATP-binding subunit ClpC	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
copA, ATP7; Cu+-exporting ATPase [EC:3.6.3.54]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
ctpE; cation-transporting P-type ATPase E [EC:3.6.3.-]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
ecfA1; energy-coupling factor transport system ATP-binding protein [EC:3.6.3.-]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
endA; DNA-entry nuclease	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
INV, sacA; beta-fructofuranosidase [EC:3.2.1.26]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
lacC; tagatose 6-phosphate kinase [EC:2.7.1.144]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
pnuC; nicotinamide mononucleotide transporter	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
udk, UCK; uridine kinase [EC:2.7.1.48]	0.07831	0.00217	0.08111	0.00056	0.00293	65	0.07635	0.00088	0.00307	93	0.00424	1.12099	153.15	0.26405	0.32890
aadK; aminoglycoside 6-adenylyltransferase [EC:2.7.7.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ABC.SS.A; simple sugar transport system ATP-binding protein [EC:3.6.3.17]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ABCF3; ATP-binding cassette, subfamily F, member 3	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ackA; acetate kinase [EC:2.7.2.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
acm; lysozyme	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
acuB; acetoin utilization protein AcuB	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
acyP; acylphosphatase [EC:3.6.1.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
addA; ATP-dependent helicase/nuclease subunit A [EC:3.1.-.- 3.6.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
addB; ATP-dependent helicase/nuclease subunit B [EC:3.1.-.- 3.6.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
adk, AK; adenylate kinase [EC:2.7.4.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
agaS; tagatose-6-phosphate ketose/aldose isomerase [EC:5.-.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
alr; alanine racemase [EC:5.1.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
alsD, budA, aldC; acetolactate decarboxylase [EC:4.1.1.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ampC; beta-lactamase class C [EC:3.5.2.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ampS, pepS, ampT; aminopeptidase [EC:3.4.11.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
AMY, amyA, malS; alpha-amylase [EC:3.2.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
apbE; FAD:protein FMN transferase [EC:2.7.1.180]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
APRT, apt; adenine phosphoribosyltransferase [EC:2.4.2.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
AROA1, aroA; chorismate mutase [EC:5.4.99.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
aroB; 3-dehydroquinate synthase [EC:4.2.3.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
aroC; chorismate synthase [EC:4.2.3.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
aroE; shikimate dehydrogenase [EC:1.1.1.25]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
asp1; accessory secretory protein Asp1	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
asp2; accessory secretory protein Asp2	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
asp3; accessory secretory protein Asp3	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ATPF0A, atpB; F-type H+-transporting ATPase subunit a	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ATPF0B, atpF; F-type H+-transporting ATPase subunit b	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ATPF0C, atpE; F-type H+-transporting ATPase subunit c	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ATPF1A, atpA; F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ATPF1B, atpD; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ATPF1D, atpH; F-type H+-transporting ATPase subunit delta	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ATPF1E, atpC; F-type H+-transporting ATPase subunit epsilon	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ATPF1G, atpG; F-type H+-transporting ATPase subunit gamma	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
bgaB, lacA; beta-galactosidase [EC:3.2.1.23]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
bioY; biotin transport system substrate-specific component	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
birA; BirA family transcriptional regulator, biotin operon repressor / biotin—[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
bmpA, bmpB, tmpC; basic membrane protein A and related proteins	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
capA, pgsA; gamma-polyglutamate biosynthesis protein CapA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
carA, CPA1; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
catE; catechol 2,3-dioxygenase [EC:1.13.11.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cbf, cbf1; 3’-5’ exoribonuclease [EC:3.1.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cdd, CDA; cytidine deaminase [EC:3.5.4.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ciaR; two-component system, OmpR family, response regulator CiaR	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cidA; holin-like protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
clpE; ATP-dependent Clp protease ATP-binding subunit ClpE	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
clpL; ATP-dependent Clp protease ATP-binding subunit ClpL	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
clpX, CLPX; ATP-dependent Clp protease ATP-binding subunit ClpX	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cmk; CMP/dCMP kinase [EC:2.7.4.25]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
coaA; type I pantothenate kinase [EC:2.7.1.33]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
coaE; dephospho-CoA kinase [EC:2.7.1.24]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
codY; transcriptional pleiotropic repressor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
coiA; competence protein CoiA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comEA; competence protein ComEA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comEB; dCMP deaminase [EC:3.5.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comEC; competence protein ComEC	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comFA; competence protein ComFA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comFC; competence protein ComFC	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comGA; competence protein ComGA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comGB; competence protein ComGB	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comGC; competence protein ComGC	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comGD; competence protein ComGD	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
comGF; competence protein ComGF	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
corA; magnesium transporter	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cshB; ATP-dependent RNA helicase CshB [EC:3.6.4.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ctsR; transcriptional regulator of stress and heat shock response	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cutC; copper homeostasis protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cycB, ganO; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cynT, can; carbonic anhydrase [EC:4.2.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cysE; serine O-acetyltransferase [EC:2.3.1.30]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
cysK; cysteine synthase A [EC:2.5.1.47]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
czcD, zitB; cobalt-zinc-cadmium efflux system protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dacA; diadenylate cyclase [EC:2.7.7.85]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dacC, dacA, dacD; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dapL; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
deaD, cshA; ATP-dependent RNA helicase DeaD [EC:3.6.4.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
degP, htrA; serine protease Do [EC:3.4.21.107]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
deoB; phosphopentomutase [EC:5.4.2.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
deoC, DERA; deoxyribose-phosphate aldolase [EC:4.1.2.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dgkA; undecaprenol kinase [EC:2.7.1.66]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
DHFR, folA; dihydrofolate reductase [EC:1.5.1.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dinB; DNA polymerase IV [EC:2.7.7.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dinG; ATP-dependent DNA helicase DinG [EC:3.6.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dinJ; DNA-damage-inducible protein J	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
divIC, divA; cell division protein DivIC	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
divIVA; cell division initiation protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
DLD, lpd, pdhD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dltA; D-alanine–poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dltB; membrane protein involved in D-alanine export	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dltC; D-alanine–poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dltD; D-alanine transfer protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaA; chromosomal replication initiator protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaB; replication initiation and membrane attachment protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaB; replicative DNA helicase [EC:3.6.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaD; DNA replication protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaG; DNA primase [EC:2.7.7.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaI; primosomal protein DnaI	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaJ; molecular chaperone DnaJ	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaK, HSPA9; molecular chaperone DnaK	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dps; starvation-inducible DNA-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dtd, DTD1; D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E1.1.1.3; homoserine dehydrogenase [EC:1.1.1.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E1.2.3.3, poxL; pyruvate oxidase [EC:1.2.3.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E1.7.1.7, guaC; GMP reductase [EC:1.7.1.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.3.1.8, pta; phosphate acetyltransferase [EC:2.3.1.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.3.3.10; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.7.1.36, MVK, mvaK1; mevalonate kinase [EC:2.7.1.36]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.7.1.71, aroK, aroL; shikimate kinase [EC:2.7.1.71]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.7.4.2, mvaK2; phosphomevalonate kinase [EC:2.7.4.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.7.4.8, gmk; guanylate kinase [EC:2.7.4.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.7.6.5X; putative GTP pyrophosphokinase [EC:2.7.6.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.7.7.3A, coaD, kdtB; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E2.7.7.41, CDS1, CDS2, cdsA; phosphatidate cytidylyltransferase [EC:2.7.7.41]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.1.11.2, xthA; exodeoxyribonuclease III [EC:3.1.11.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.1.3.16; protein phosphatase [EC:3.1.3.16]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.1.3.25, IMPA, suhB; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.1.3.41; 4-nitrophenyl phosphatase [EC:3.1.3.41]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.1.4.46, glpQ, ugpQ; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.2.1.85, lacG; 6-phospho-beta-galactosidase [EC:3.2.1.85]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.4.13.-; D-alanyl-D-alanine dipeptidase [EC:3.4.13.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.5.1.1, ansA, ansB; L-asparaginase [EC:3.5.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E3.6.3.8; Ca2+-transporting ATPase [EC:3.6.3.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E4.1.3.3, nanA, NPL; N-acetylneuraminate lyase [EC:4.1.3.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E4.3.1.19, ilvA, tdcB; threonine dehydratase [EC:4.3.1.19]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
efp; elongation factor P	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
engA, der; GTPase	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
engB; GTP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ENO, eno; enolase [EC:4.2.1.11]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
era, ERAL1; GTPase	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
estA; putative tributyrin esterase [EC:3.1.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
eta; exfoliative toxin A/B	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ezrA; septation ring formation regulator	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fer; ferredoxin	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
flA; adenosyl-fluoride synthase [EC:2.5.1.63]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
folP; dihydropteroate synthase [EC:2.5.1.15]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
frr, MRRF, RRF; ribosome recycling factor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fruK; 1-phosphofructokinase [EC:2.7.1.56]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fruR2, fruR; DeoR family transcriptional regulator, fructose operon transcriptional repressor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ftsA; cell division protein FtsA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ftsE; cell division transport system ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ftsH, hflB; cell division protease FtsH [EC:3.4.24.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ftsQ; cell division protein FtsQ	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ftsW, spoVE; cell division protein FtsW	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ftsX; cell division transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ftsY; fused signal recognition particle receptor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ftsZ; cell division protein FtsZ	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
fusA, GFM, EFG; elongation factor G	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
galK; galactokinase [EC:2.7.1.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
galM, GALM; aldose 1-epimerase [EC:5.1.3.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
galT, GALT; UDPglucose–hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gatA, QRSL1; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gatB, PET112; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gatC, GATC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
GBE1, glgB; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
GCH1, folE; GTP cyclohydrolase IA [EC:3.5.4.16]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gidA, mnmG, MTO1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gidB, rsmG; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glgA; starch synthase [EC:2.4.1.21]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glk; glucokinase [EC:2.7.1.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glmM; phosphoglucosamine mutase [EC:5.4.2.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glmS, GFPT; glucosamine—fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glnA, GLUL; glutamine synthetase [EC:6.3.1.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glnR; MerR family transcriptional regulator, glutamine synthetase repressor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
GLO1, gloA; lactoylglutathione lyase [EC:4.4.1.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glpK, GK; glycerol kinase [EC:2.7.1.30]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glxK, garK; glycerate 2-kinase [EC:2.7.1.165]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gph; phosphoglycolate phosphatase [EC:3.1.3.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gpx; glutathione peroxidase [EC:1.11.1.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
greA; transcription elongation factor GreA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
groEL, HSPD1; chaperonin GroEL	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
groES, HSPE1; chaperonin GroES	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
GRPE; molecular chaperone GrpE	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
GSP13; general stress protein 13	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
GSR, gor; glutathione reductase (NADPH) [EC:1.8.1.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gyrA; DNA gyrase subunit A [EC:5.99.1.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
gyrB; DNA gyrase subunit B [EC:5.99.1.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.99.1.1 4.99.1.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hemK, prmC, HEMK; release factor glutamine methyltransferase [EC:2.1.1.297]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hemN, hemZ; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hflX; GTPase	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
HINT1, hinT, hit; histidine triad (HIT) family protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hlyIII; hemolysin III	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
holA; DNA polymerase III subunit delta [EC:2.7.7.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
holB; DNA polymerase III subunit delta’ [EC:2.7.7.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hprK, ptsK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hprT, hpt, HPRT1; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hrcA; heat-inducible transcriptional repressor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hslO; molecular chaperone Hsp33	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
htpX; heat shock protein HtpX [EC:3.4.24.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
htsT; energy-coupling factor transport system substrate-specific component	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
hupB; DNA-binding protein HU-beta	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
idi, IDI; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
infA; translation initiation factor IF-1	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
infB, MTIF2; translation initiation factor IF-2	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
infC, MTIF3; translation initiation factor IF-3	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
iscU, nifU; nitrogen fixation protein NifU and related proteins	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
jag; spoIIIJ-associated protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K00243; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K03710; GntR family transcriptional regulator	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K06878; tRNA-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K06885; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K06890; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K06929; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K06940; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K06960; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07009; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07015; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07030; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07040; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07058; membrane protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07082; UPF0755 protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07089; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07095; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07105; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07124; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07139; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07146; UPF0176 protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07166; ACT domain-containing protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07177; Lon-like protease	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K07461; putative endonuclease	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K08303; putative protease [EC:3.4.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K08884; serine/threonine protein kinase, bacterial [EC:2.7.11.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K08974; putative membrane protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K08987; putative membrane protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K08998; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09155; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09157; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09747; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09762; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09787; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09790; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09861; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09962; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K09976; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K11145; ribonuclease III family protein [EC:3.1.26.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
K17076, lysY; putative lysine transport system ATP-binding protein [EC:3.6.3.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
kch, trkA, mthK, pch; voltage-gated potassium channel	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lacT; transcriptional antiterminator	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lemA; LemA protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lepA; GTP-binding protein LepA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
leuA, IMS; 2-isopropylmalate synthase [EC:2.3.3.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
leuB, IMDH; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
leuC, IPMI-L; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lgt, umpA; phosphatidylglycerol:prolipoprotein diacylglycerol transferase [EC:2.-.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
liaR; two-component system, NarL family, response regulator LiaR	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
livF; branched-chain amino acid transport system ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
livG; branched-chain amino acid transport system ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
livH; branched-chain amino acid transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
livK; branched-chain amino acid transport system substrate-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
livM; branched-chain amino acid transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lplA, lplJ; lipoate—protein ligase [EC:6.3.1.20]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lspA; signal peptidase II [EC:3.4.23.36]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lysA; diaminopimelate decarboxylase [EC:4.1.1.20]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lysC; aspartate kinase [EC:2.7.2.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
lysX2; putative lysine transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
maa; maltose O-acetyltransferase [EC:2.3.1.79]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
manA, MPI; mannose-6-phosphate isomerase [EC:5.3.1.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
map; methionyl aminopeptidase [EC:3.4.11.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mapP; maltose 6’-phosphate phosphatase [EC:3.1.3.90]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mecA1_2; adapter protein MecA 1/2	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
metB; cystathionine gamma-synthase [EC:2.5.1.48]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
metE; 5-methyltetrahydropteroyltriglutamate–homocysteine methyltransferase [EC:2.1.1.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
metF, MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
metK; S-adenosylmethionine synthetase [EC:2.5.1.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
metN; D-methionine transport system ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
metQ; D-methionine transport system substrate-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mfd; transcription-repair coupling factor (superfamily II helicase) [EC:3.6.4.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
MFS.CP; MFS transporter, CP family, cyanate transporter	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mgs, bgsB; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mgtA, mgtB; Mg2+-importing ATPase [EC:3.6.3.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
miaA, TRIT1; tRNA dimethylallyltransferase [EC:2.5.1.75]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mnmA, trmU; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mnmE, trmE, MSS1; tRNA modification GTPase [EC:3.6.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mraW, rsmH; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mrcA; penicillin-binding protein 1A [EC:2.4.1.129 3.4.16.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mreC; rod shape-determining protein MreC	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mreD; rod shape-determining protein MreD	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mscL; large conductance mechanosensitive channel	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mscS; small conductance mechanosensitive channel	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
MTFMT, fmt; methionyl-tRNA formyltransferase [EC:2.1.2.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mtnN, mtn, pfs; adenosylhomocysteine nucleosidase [EC:3.2.2.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mtsA; iron/zinc/manganese/copper transport system substrate-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mtsB; iron/zinc/manganese/copper transport system ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mtsC; iron/zinc/manganese/copper transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mtsT; energy-coupling factor transport system substrate-specific component	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murC; UDP-N-acetylmuramate–alanine ligase [EC:6.3.2.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murD; UDP-N-acetylmuramoylalanine–D-glutamate ligase [EC:6.3.2.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase [EC:6.3.2.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murF; UDP-N-acetylmuramoyl-tripeptide–D-alanyl-D-alanine ligase [EC:6.3.2.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murG; UDP-N-acetylglucosamine–N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murI; glutamate racemase [EC:5.1.1.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murM; serine/alanine adding enzyme [EC:2.3.2.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
murN; alanine adding enzyme [EC:2.3.2.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mutL; DNA mismatch repair protein MutL	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mutM, fpg; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mutS; DNA mismatch repair protein MutS	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mutS2; DNA mismatch repair protein MutS2	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
MVD, mvaD; diphosphomevalonate decarboxylase [EC:4.1.1.33]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nadE; NAD+ synthase [EC:6.3.1.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nagA, AMDHD2; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
NARS, asnS; asparaginyl-tRNA synthetase [EC:6.1.1.22]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
niaX; niacin transporter	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
npdA; NAD-dependent deacetylase [EC:3.5.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nrdH; glutaredoxin-like protein NrdH	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nrdR; transcriptional repressor NrdR	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
NTH; endonuclease III [EC:4.2.99.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nusA; N utilization substance protein A	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nusB; N utilization substance protein B	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
nusG; transcriptional antiterminator NusG	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
obgE, cgtA; GTPase [EC:3.6.5.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ogt, MGMT; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
oppB; oligopeptide transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
oppC; oligopeptide transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
oppD; oligopeptide transport system ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
oppF; oligopeptide transport system ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
opuA; osmoprotectant transport system ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
opuBD; osmoprotectant transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
paaI; acyl-CoA thioesterase [EC:3.1.2.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
parB, spo0J; chromosome partitioning protein, ParB family	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
parC; topoisomerase IV subunit A [EC:5.99.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
parE; topoisomerase IV subunit B [EC:5.99.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
patA, rscA, lmrC, satA; ATP-binding cassette, subfamily B, multidrug efflux pump	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
patA; aminotransferase [EC:2.6.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
patB, malY; cystathione beta-lyase [EC:4.4.1.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
patB, rscB, lmrC, satB; ATP-binding cassette, subfamily B, multidrug efflux pump	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pbp1b; penicillin-binding protein 1B	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pbp2A; penicillin-binding protein 2A [EC:2.4.1.129 3.4.16.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pbp2B, penA; penicillin-binding protein 2B	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pbp2X; penicillin-binding protein 2X	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pbuG; putative MFS transporter, AGZA family, xanthine/uracil permease	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PDHA, pdhA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PDHB, pdhB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pepA; glutamyl aminopeptidase [EC:3.4.11.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pepF, pepB; oligoendopeptidase F [EC:3.4.24.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pepN; aminopeptidase N [EC:3.4.11.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pepO; putative endopeptidase [EC:3.4.24.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pepT; tripeptide aminopeptidase [EC:3.4.11.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PGD, gnd, gntZ; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pgl; 6-phosphogluconolactonase [EC:3.1.1.31]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pgm; phosphoglucomutase [EC:5.4.2.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pgsA, PGS1; CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pheA2; prephenate dehydratase [EC:4.2.1.51]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
phnA; protein PhnA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
phoH, phoL; phosphate starvation-inducible protein PhoH and related proteins	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
phoU; phosphate transport system protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PK, pyk; pyruvate kinase [EC:2.7.1.40]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
plsX; glycerol-3-phosphate acyltransferase PlsX [EC:2.3.1.15]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
plsY; glycerol-3-phosphate acyltransferase PlsY [EC:2.3.1.15]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pncB, NAPRT1; nicotinate phosphoribosyltransferase [EC:6.3.4.21]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
polA; DNA polymerase I [EC:2.7.7.7]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
potA; spermidine/putrescine transport system ATP-binding protein [EC:3.6.3.31]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
potB; spermidine/putrescine transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
potC; spermidine/putrescine transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
potD; spermidine/putrescine transport system substrate-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PPCDC, coaC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PPCS, COAB; phosphopantothenate—cysteine ligase (ATP) [EC:6.3.2.51]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pphA; serine/threonine protein phosphatase 1 [EC:3.1.3.16]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ppnK, NADK; NAD+ kinase [EC:2.7.1.23]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
praC, xylH; 4-oxalocrotonate tautomerase [EC:5.3.2.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
prfA, MTRF1, MRF1; peptide chain release factor 1	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
prfB; peptide chain release factor 2	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
prfC; peptide chain release factor 3	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
priA; primosomal protein N’ (replication factor Y) (superfamily II helicase) [EC:3.6.4.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
proB; glutamate 5-kinase [EC:2.7.2.11]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
prsA; foldase protein PrsA [EC:5.2.1.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pstA; phosphate transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pstC; phosphate transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pstS; phosphate transport system substrate-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTH1, pth, spoVC; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-Aga-EIIA, agaF; PTS system, N-acetylgalactosamine-specific IIA component [EC:2.7.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-EI.PTSI, ptsI; phosphotransferase system, enzyme I, PtsI [EC:2.7.3.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-Fru-EIIC, fruA; PTS system, fructose-specific IIC component	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-Fru1-EIID, levG; PTS system, fructose-specific IID component	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-Glc-EIIC, ptsG; PTS system, glucose-specific IIC component	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-HPR; phosphocarrier protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-Lac-EIIA, lacF; PTS system, lactose-specific IIA component [EC:2.7.1.207]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-Lac-EIIC, lacE; PTS system, lactose-specific IIC component	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-Man-EIIA, manX; PTS system, mannose-specific IIA component [EC:2.7.1.191]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
PTS-Scr-EIIC, scrA, sacP, sacX, ptsS; PTS system, sucrose-specific IIC component	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
punA, PNP; purine-nucleoside phosphorylase [EC:2.4.2.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purD; phosphoribosylamine—glycine ligase [EC:6.3.4.13]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
purR; purine operon repressor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrB, PYR2; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrDII; dihydroorotate dehydrogenase electron transfer subunit	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrF; orotidine-5’-phosphate decarboxylase [EC:4.1.1.23]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrG, CTPS; CTP synthase [EC:6.3.4.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrH; uridylate kinase [EC:2.7.4.22]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
pyrP, uraA; uracil permease	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
radA, sms; DNA repair protein RadA/Sms	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
radC; DNA repair protein RadC	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rapZ; RNase adapter protein RapZ	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rbfA; ribosome-binding factor A	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rbgA; ribosome biogenesis GTPase A	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rbsB; ribose transport system substrate-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recA; recombination protein RecA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recF; DNA replication and repair protein RecF	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recG; ATP-dependent DNA helicase RecG [EC:3.6.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recN; DNA repair protein RecN (Recombination protein N)	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recO; DNA repair protein RecO (recombination protein O)	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recR; recombination protein RecR	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recU; recombination protein U	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
recX; regulatory protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
relA; GTP pyrophosphokinase [EC:2.7.6.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rex; redox-sensing transcriptional repressor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ridA, tdcF, RIDA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rimM; 16S rRNA processing protein RimM	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rimP; ribosome maturation factor RimP	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rlmB; 23S rRNA (guanosine2251-2’-O)-methyltransferase [EC:2.1.1.185]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rmuC; DNA recombination protein RmuC	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rnhC; ribonuclease HIII [EC:3.1.26.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rnmV; ribonuclease M5 [EC:3.1.26.8]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rnpA; ribonuclease P protein component [EC:3.1.26.5]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rnr, vacB; ribonuclease R [EC:3.1.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rny; ribonucrease Y [EC:3.1.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rnz; ribonuclease Z [EC:3.1.26.11]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rodA, mrdB; rod shape determining protein RodA	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L1, MRPL1, rplA; large subunit ribosomal protein L1	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L11, MRPL11, rplK; large subunit ribosomal protein L11	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L13, MRPL13, rplM; large subunit ribosomal protein L13	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L14, MRPL14, rplN; large subunit ribosomal protein L14	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L15, MRPL15, rplO; large subunit ribosomal protein L15	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L16, MRPL16, rplP; large subunit ribosomal protein L16	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L18, MRPL18, rplR; large subunit ribosomal protein L18	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L19, MRPL19, rplS; large subunit ribosomal protein L19	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L2, MRPL2, rplB; large subunit ribosomal protein L2	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L20, MRPL20, rplT; large subunit ribosomal protein L20	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L21, MRPL21, rplU; large subunit ribosomal protein L21	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L22, MRPL22, rplV; large subunit ribosomal protein L22	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L23, MRPL23, rplW; large subunit ribosomal protein L23	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L24, MRPL24, rplX; large subunit ribosomal protein L24	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L27, MRPL27, rpmA; large subunit ribosomal protein L27	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L29, rpmC; large subunit ribosomal protein L29	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L3, MRPL3, rplC; large subunit ribosomal protein L3	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L30, MRPL30, rpmD; large subunit ribosomal protein L30	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L31, rpmE; large subunit ribosomal protein L31	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L32, MRPL32, rpmF; large subunit ribosomal protein L32	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L34, MRPL34, rpmH; large subunit ribosomal protein L34	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L35, MRPL35, rpmI; large subunit ribosomal protein L35	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L4, MRPL4, rplD; large subunit ribosomal protein L4	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L5, MRPL5, rplE; large subunit ribosomal protein L5	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L6, MRPL6, rplF; large subunit ribosomal protein L6	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-L9, MRPL9, rplI; large subunit ribosomal protein L9	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S1, rpsA; small subunit ribosomal protein S1	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S10, MRPS10, rpsJ; small subunit ribosomal protein S10	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S13, rpsM; small subunit ribosomal protein S13	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S14, MRPS14, rpsN; small subunit ribosomal protein S14	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S17, MRPS17, rpsQ; small subunit ribosomal protein S17	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S19, rpsS; small subunit ribosomal protein S19	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S20, rpsT; small subunit ribosomal protein S20	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S21, MRPS21, rpsU; small subunit ribosomal protein S21	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S3, rpsC; small subunit ribosomal protein S3	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S4, rpsD; small subunit ribosomal protein S4	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S8, rpsH; small subunit ribosomal protein S8	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rpe, RPE; ribulose-phosphate 3-epimerase [EC:5.1.3.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rpoC; DNA-directed RNA polymerase subunit beta’ [EC:2.7.7.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rpoD; RNA polymerase primary sigma factor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rpoE; DNA-directed RNA polymerase subunit delta	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rseP; regulator of sigma E protease [EC:3.4.24.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rsgA, engC; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rsmB, sun; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rsmI; 16S rRNA (cytidine1402-2’-O)-methyltransferase [EC:2.1.1.198]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ruvA; holliday junction DNA helicase RuvA [EC:3.6.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ruvB; holliday junction DNA helicase RuvB [EC:3.6.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ruvX; putative holliday junction resolvase [EC:3.1.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
saeR; two-component system, OmpR family, response regulator SaeR	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
scpA; segregation and condensation protein A	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
scpB; segregation and condensation protein B	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
scrR; LacI family transcriptional regulator, sucrose operon repressor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
secG; preprotein translocase subunit SecG	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
sepF; cell division inhibitor SepF	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
serB, PSPH; phosphoserine phosphatase [EC:3.1.3.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
smc; chromosome segregation protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
smf; DNA processing protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
smpB; SsrA-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
spoU; RNA methyltransferase, TrmH family	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
SRP54, ffh; signal recognition particle subunit SRP54 [EC:3.6.5.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
sstT; serine/threonine transporter	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
sufC; Fe-S cluster assembly ATP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
sufD; Fe-S cluster assembly protein SufD	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
sulD; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:4.1.2.25 2.7.6.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tatD; TatD DNase family protein [EC:3.1.21.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
TC.APA; basic amino acid/polyamine antiporter, APA family	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
TC.MATE, SLC47A, norM, mdtK, dinF; multidrug resistance protein, MATE family	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tdk, TK; thymidine kinase [EC:2.7.1.21]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tehB; tellurite methyltransferase [EC:2.1.1.265]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tex; protein Tex	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tgt, QTRT1; queuine tRNA-ribosyltransferase [EC:2.4.2.29]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
thiN, TPK1, THI80; thiamine pyrophosphokinase [EC:2.7.6.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
thrB1; homoserine kinase [EC:2.7.1.39]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
thrC; threonine synthase [EC:4.2.3.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
thyA, TYMS; thymidylate synthase [EC:2.1.1.45]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tig; trigger factor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tilS, mesJ; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tlyA; 23S rRNA (cytidine1920-2’-O)/16S rRNA (cytidine1409-2’-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tlyC; putative hemolysin	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tmk, DTYMK; dTMP kinase [EC:2.7.4.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
topA; DNA topoisomerase I [EC:5.99.1.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tpx; thiol peroxidase, atypical 2-Cys peroxiredoxin [EC:1.11.1.15]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trmB, METTL1; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trmFO, gid; methylenetetrahydrofolate–tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trmL, cspR; tRNA (cytidine/uridine-2’-O-)-methyltransferase [EC:2.1.1.207]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trpA; tryptophan synthase alpha chain [EC:4.2.1.20]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trpE; anthranilate synthase component I [EC:4.1.3.27]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
trpG; anthranilate synthase component II [EC:4.1.3.27]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
truA, PUS1; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
truB, PUS4, TRUB1; tRNA pseudouridine55 synthase [EC:5.4.99.25]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tsaC, rimN, SUA5; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tsf, TSFM; elongation factor Ts	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tuf, TUFM; elongation factor Tu	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
typA, bipA; GTP-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
tyrA2; prephenate dehydrogenase [EC:1.3.1.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
UGP2, galU, galF; UTP–glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
umuC; DNA polymerase V	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
UNG, UDG; uracil-DNA glycosylase [EC:3.2.2.27]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
upp, UPRT; uracil phosphoribosyltransferase [EC:2.4.2.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
URA4, pyrC; dihydroorotase [EC:3.5.2.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
uup; ABC transport system ATP-binding/permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
uvrA; excinuclease ABC subunit A	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
uvrB; excinuclease ABC subunit B	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
uvrC; excinuclease ABC subunit C	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
uvrD, pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
vicR; two-component system, OmpR family, response regulator VicR	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yafQ; mRNA interferase YafQ [EC:3.1.-.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yajC; preprotein translocase subunit YajC	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ybaK, ebsC; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ybeB; ribosome-associated protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ybeY, yqfG; probable rRNA maturation factor	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ycaJ; putative ATPase	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ycgQ; putative membrane protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ychF; ribosome-binding ATPase	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ygaC; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yggS, PROSC; PLP dependent protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yggT; YggT family protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yhbH; putative sigma-54 modulation protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yhbY; RNA-binding protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yhgE; putative membrane protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yjbB; phosphate:Na+ symporter	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ylxR; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
yqeH; 30S ribosome assembly GTPase	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ysxB; uncharacterized protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
znuB; zinc transport system permease protein	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
znuC; zinc transport system ATP-binding protein [EC:3.6.3.-]	0.07827	0.00217	0.08106	0.00056	0.00293	65	0.07631	0.00087	0.00307	93	0.00424	1.12102	153.16	0.26403	0.32890
ABC.GLN1.A; putative glutamine transport system ATP-binding protein [EC:3.6.3.-]	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
ABC.GLN1.S; putative glutamine transport system substrate-binding protein	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
dhaL; phosphoenolpyruvate—glycerone phosphotransferase subunit DhaL [EC:2.7.1.121]	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
PTS-Ula-EIIB, ulaB, sgaB; PTS system, ascorbate-specific IIB component [EC:2.7.1.194]	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
PTS-Ula-EIIC, ulaA, sgaT; PTS system, ascorbate-specific IIC component	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
TC.AGCS; alanine or glycine:cation symporter, AGCS family	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
tcyK; L-cystine transport system substrate-binding protein	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
tcyL; L-cystine transport system permease protein	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
tcyN; L-cystine transport system ATP-binding protein [EC:3.6.3.-]	0.07822	0.00217	0.08102	0.00056	0.00293	65	0.07627	0.00087	0.00306	93	0.00424	1.12082	153.17	0.26412	0.32890
pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]	0.06953	0.00396	0.06840	0.00196	0.00550	65	0.07032	0.00285	0.00554	93	0.00780	-0.24563	151.37	0.80630	0.83385
PTS-Cel-EIIC, celB, chbC; PTS system, cellobiose-specific IIC component	0.06945	0.00395	0.06831	0.00197	0.00550	65	0.07024	0.00284	0.00553	93	0.00780	-0.24646	151.19	0.80566	0.83385
DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]	0.04359	0.00219	0.04695	0.00063	0.00312	65	0.04123	0.00084	0.00301	93	0.00434	1.31870	148.99	0.18929	0.32890
FUCA; alpha-L-fucosidase [EC:3.2.1.51]	0.04359	0.00219	0.04695	0.00063	0.00312	65	0.04123	0.00084	0.00301	93	0.00434	1.31870	148.99	0.18929	0.32890
aqpZ; aquaporin Z	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
butA, budC; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
comB; competence factor transport accessory protein ComB	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
K07485; transposase	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
K09704; uncharacterized protein	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
lctO; L-lactate oxidase [EC:1.1.3.2]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
MAN2C1; alpha-mannosidase [EC:3.2.1.24]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
pbuX; xanthine permease	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
pezA; HTH-type transcriptional regulator / antitoxin PezA	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
pezT; UDP-N-acetylglucosamine kinase [EC:2.7.1.176]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
PTS-Gat-EIIA, gatA, sgcA; PTS system, galactitol-specific IIA component [EC:2.7.1.200]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
PTS-Gat-EIIB, gatB, sgcB; PTS system, galactitol-specific IIB component [EC:2.7.1.200]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
PTS-Gat-EIIC, gatC, sgcC; PTS system, galactitol-specific IIC component	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
queH; epoxyqueuosine reductase [EC:1.17.99.6]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
relE, stbE; mRNA interferase RelE/StbE	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
speG, SAT; diamine N-acetyltransferase [EC:2.3.1.57]	0.04354	0.00219	0.04691	0.00063	0.00311	65	0.04119	0.00085	0.00302	93	0.00433	1.31868	149.16	0.18930	0.32890
adh2; alcohol dehydrogenase [EC:1.1.1.-]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
afuA, fbpA; iron(III) transport system substrate-binding protein	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
afuB, fbpB; iron(III) transport system permease protein	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
afuC, fbpC; iron(III) transport system ATP-binding protein [EC:3.6.3.30]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
aguA; agmatine deiminase [EC:3.5.3.12]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
asnA; aspartate–ammonia ligase [EC:6.3.1.1]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
cah; cephalosporin-C deacetylase [EC:3.1.1.41]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
cpoA; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-galactosyltransferase [EC:2.4.1.-]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
dhaK; phosphoenolpyruvate—glycerone phosphotransferase subunit DhaK [EC:2.7.1.121]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
doc; death on curing protein	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
E2.7.13.3; histidine kinase [EC:2.7.13.3]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
E3.2.1.96; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [EC:3.2.1.96]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
E4.1.1.18, ldcC, cadA; lysine decarboxylase [EC:4.1.1.18]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
E4.1.1.19; arginine decarboxylase [EC:4.1.1.19]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
E4.6.1.1B, cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
K06915; uncharacterized protein	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
K07133; uncharacterized protein	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
mmr; MFS transporter, DHA2 family, methylenomycin A resistance protein	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
ndk, NME; nucleoside-diphosphate kinase [EC:2.7.4.6]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
pcp; pyroglutamyl-peptidase [EC:3.4.19.3]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
pdxS, pdx1; pyridoxal 5’-phosphate synthase pdxS subunit [EC:4.3.3.6]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
pdxT, pdx2; 5’-phosphate synthase pdxT subunit [EC:4.3.3.6]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
slo; thiol-activated cytolysin	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
speE, SRM; spermidine synthase [EC:2.5.1.16]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
tarJ; ribitol-5-phosphate 2-dehydrogenase (NADP+) [EC:1.1.1.405]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
TC.AAT; amino acid transporter, AAT family	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
TC.CPA1; monovalent cation:H+ antiporter, CPA1 family	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
TC.NSS; neurotransmitter:Na+ symporter, NSS family	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
TC.POT; proton-dependent oligopeptide transporter, POT family	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
xerD; integrase/recombinase XerD	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
yefM; antitoxin YefM	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
ykoE; energy-coupling factor transport system substrate-specific component	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
ytmI; uncharacterized N-acetyltransferase [EC:2.3.1.-]	0.04350	0.00219	0.04686	0.00063	0.00311	65	0.04115	0.00085	0.00302	93	0.00433	1.31839	149.34	0.18939	0.32890
E3.4.21.96; lactocepin [EC:3.4.21.96]	0.03485	0.00198	0.03429	0.00049	0.00274	65	0.03525	0.00072	0.00278	93	0.00391	-0.24380	151.71	0.80772	0.83385
E2.6.1.11, argD; acetylornithine aminotransferase [EC:2.6.1.11]	0.03481	0.00198	0.03425	0.00049	0.00274	65	0.03520	0.00072	0.00277	93	0.00390	-0.24475	151.54	0.80698	0.83385
HEXA_B; hexosaminidase [EC:3.2.1.52]	0.03481	0.00198	0.03425	0.00049	0.00274	65	0.03520	0.00072	0.00277	93	0.00390	-0.24475	151.54	0.80698	0.83385
rgpA; rhamnosyltransferase [EC:2.4.1.-]	0.03481	0.00198	0.03425	0.00049	0.00274	65	0.03520	0.00072	0.00277	93	0.00390	-0.24475	151.54	0.80698	0.83385
ACO, acnA; aconitate hydratase [EC:4.2.1.3]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
acrR, smeT; TetR/AcrR family transcriptional regulator, acrAB operon repressor	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ald; alanine dehydrogenase [EC:1.4.1.1]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
aphA; kanamycin kinase [EC:2.7.1.95]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
arcA; arginine deiminase [EC:3.5.3.6]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
arcC; carbamate kinase [EC:2.7.2.2]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
argB; acetylglutamate kinase [EC:2.7.2.8]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
argH, ASL; argininosuccinate lyase [EC:4.3.2.1]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ATPVA, ntpA, atpA; V/A-type H+/Na+-transporting ATPase subunit A [EC:3.6.3.14 3.6.3.15]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ATPVB, ntpB, atpB; V/A-type H+/Na+-transporting ATPase subunit B	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ATPVC, ntpC, atpC; V/A-type H+/Na+-transporting ATPase subunit C	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ATPVD, ntpD, atpD; V/A-type H+/Na+-transporting ATPase subunit D	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ATPVE, ntpE, atpE; V/A-type H+/Na+-transporting ATPase subunit E	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ATPVF, ntpF, atpF; V/A-type H+/Na+-transporting ATPase subunit F	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ATPVI, ntpI, atpI; V/A-type H+/Na+-transporting ATPase subunit I	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ATPVK, ntpK, atpK; V/A-type H+/Na+-transporting ATPase subunit K	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
BDH, butB; (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.4 1.1.1.- 1.1.1.303]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
CHO1, pssA; CDP-diacylglycerol—serine O-phosphatidyltransferase [EC:2.7.8.8]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
CS, gltA; citrate synthase [EC:2.3.3.1]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
dgs, bgsA; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E1.1.1.1, adh; alcohol dehydrogenase [EC:1.1.1.1]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E2.4.-.-; glycosyltransferase [EC:2.4.-.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E2.4.1.5; dextransucrase [EC:2.4.1.5]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E2.7.1.4, scrK; fructokinase [EC:2.7.1.4]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E2.7.7.24, rfbA, rffH; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E3.1.3.5; 5’-nucleotidase [EC:3.1.3.5]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E4.2.1.46, rfbB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
E4.3.1.4; formiminotetrahydrofolate cyclodeaminase [EC:4.3.1.4]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
efeB; deferrochelatase/peroxidase EfeB [EC:1.11.1.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
efeO; iron uptake system component EfeO	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
efrA; ATP-binding cassette, subfamily B, multidrug efflux pump	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
efrB; ATP-binding cassette, subfamily B, multidrug efflux pump	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
elaA; ElaA protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
fctD; glutamate formiminotransferase [EC:2.1.2.5]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
FLOT; flotillin	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
fruA; fructan beta-fructosidase [EC:3.2.1.80]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
FTR, FTH1, efeU; high-affinity iron transporter	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
gltP, gltT; proton glutamate symport protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
gshA; glutamate–cysteine ligase [EC:6.3.2.2]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisD; histidinol dehydrogenase [EC:1.1.1.23]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisF; cyclase [EC:4.1.3.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisH; glutamine amidotransferase [EC:2.4.2.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hisZ; ATP phosphoribosyltransferase regulatory subunit	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hutG; formiminoglutamase [EC:3.5.3.8]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hutH, HAL; histidine ammonia-lyase [EC:4.3.1.3]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hutI, AMDHD1; imidazolonepropionase [EC:3.5.2.7]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
hutU, UROC1; urocanate hydratase [EC:4.2.1.49]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
irr; two-component system, OmpR family, response regulator Irr	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
K01436; amidohydrolase [EC:3.5.1.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
K06889; uncharacterized protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
K06950; uncharacterized protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
K07004; uncharacterized protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
K07023; putative hydrolases of HD superfamily	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
K07727; putative transcriptional regulator	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
K09153; uncharacterized protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
K13653; AraC family transcriptional regulator	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
lacY; MFS transporter, OHS family, lactose permease	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
lacZ; beta-galactosidase [EC:3.2.1.23]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
licR; lichenan operon transcriptional antiterminator	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
licT, bglG; beta-glucoside operon transcriptional antiterminator	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ltaS; lipoteichoic acid synthase [EC:2.7.8.20]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
nudB, ntpA; dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
pat; phosphinothricin acetyltransferase [EC:2.3.1.183]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
pepDA, pepDB; dipeptidase [EC:3.4.-.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
pepE; dipeptidase E [EC:3.4.13.21]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
perR; Fur family transcriptional regulator, peroxide stress response regulator	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
phnB; PhnB protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
prdX, proX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
psd, PISD; phosphatidylserine decarboxylase [EC:4.1.1.65]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
PTS-Tre-EIIC, treB; PTS system, trehalose-specific IIC component	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
rfbC, rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
rfbD, rmlD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
rgpB; rhamnosyltransferase [EC:2.4.1.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
rgpF; rhamnosyltransferase [EC:2.4.1.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
RP-L36, MRPL36, rpmJ; large subunit ribosomal protein L36	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
secE; preprotein translocase subunit SecE	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
sprL; SprT-like protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
srtB; sortase B [EC:3.4.22.70]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
tagE; poly(glycerol-phosphate) alpha-glucosyltransferase [EC:2.4.1.52]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
tatA; sec-independent protein translocase protein TatA	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
tatC; sec-independent protein translocase protein TatC	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
TC.DAACS; dicarboxylate/amino acid:cation (Na+ or H+) symporter, DAACS family	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
TC.ZIP, zupT, ZRT3, ZIP2; zinc transporter, ZIP family	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
treR2, treR; GntR family transcriptional regulator, trehalose operon transcriptional repressor	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
wecA, tagO, rfe; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
yaeR; glyoxylase I family protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
ybaZ; methylated-DNA-protein-cysteine methyltransferase related protein	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
yghU, yfcG; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
yjgM; putative acetyltransferase [EC:2.3.1.-]	0.03477	0.00198	0.03420	0.00049	0.00275	65	0.03516	0.00071	0.00277	93	0.00390	-0.24563	151.37	0.80630	0.83385
bdhAB; butanol dehydrogenase [EC:1.1.1.-]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
bglG1; transcriptional antiterminator	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
cas1; CRISP-associated protein Cas1	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
cas2; CRISPR-associated protein Cas2	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
cpdB; 2’,3’-cyclic-nucleotide 2’-phosphodiesterase / 3’-nucleotidase [EC:3.1.4.16 3.1.3.6]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
csn1, cas9; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
E2.4.1.7; sucrose phosphorylase [EC:2.4.1.7]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
E3.2.1.22B, galA, rafA; alpha-galactosidase [EC:3.2.1.22]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
E4.1.1.49, pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
gldA; glycerol dehydrogenase [EC:1.1.1.6]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
higB-1; toxin HigB-1	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
K06871; uncharacterized protein	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
K06962; uncharacterized protein	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
mmuM, BHMT2; homocysteine S-methyltransferase [EC:2.1.1.10]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
msmE; raffinose/stachyose/melibiose transport system substrate-binding protein	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
msmF; raffinose/stachyose/melibiose transport system permease protein	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
msmG; raffinose/stachyose/melibiose transport system permease protein	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
PTS-Cel-EIIA, celC, chbA; PTS system, cellobiose-specific IIA component [EC:2.7.1.196 2.7.1.205]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
PTS-Cel-EIIB, celA, chbB; PTS system, cellobiose-specific IIB component [EC:2.7.1.196 2.7.1.205]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
PTS-Ula-EIIA, ulaC, sgaA; PTS system, ascorbate-specific IIA component [EC:2.7.1.194]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
queG; epoxyqueuosine reductase [EC:1.17.99.6]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
rpoE; RNA polymerase sigma-70 factor, ECF subfamily	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-]	0.03472	0.00198	0.03416	0.00049	0.00275	65	0.03512	0.00071	0.00276	93	0.00390	-0.24646	151.19	0.80566	0.83385
parA, soj; chromosome partitioning protein	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00009	0.00000	0.00009	93	0.00012	0.04743	146.78	0.96224	0.96224
PTS-Gut-EIIC, srlA; PTS system, glucitol/sorbitol-specific IIC component	0.00009	0.00006	0.00009	0.00000	0.00009	65	0.00009	0.00000	0.00009	93	0.00012	0.04743	146.78	0.96224	0.96224
ATPVG, ahaH, atpH; V/A-type H+/Na+-transporting ATPase subunit G/H	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
cotH; spore coat protein H	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
emrE, qac, mmr, smr; small multidrug resistance pump	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
glf; UDP-galactopyranose mutase [EC:5.4.99.9]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
gloB, HAGH; hydroxyacylglutathione hydrolase [EC:3.1.2.6]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
K07054; uncharacterized protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
K07078; uncharacterized protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
K07088; uncharacterized protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
K07498; putative transposase	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
K09384; uncharacterized protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
K10120, msmE; fructooligosaccharide transport system substrate-binding protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
K10121, msmF; fructooligosaccharide transport system permease protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
K10122, msmG; fructooligosaccharide transport system permease protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
ltaE; threonine aldolase [EC:4.1.2.48]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
mntH; manganese transport protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
panE, apbA; 2-dehydropantoate 2-reductase [EC:1.1.1.169]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
proV; glycine betaine/proline transport system ATP-binding protein [EC:3.6.3.32]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
proX; glycine betaine/proline transport system substrate-binding protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
PTS-Bgl-EIIC, bglF, bglP; PTS system, beta-glucoside-specific IIC component	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
PTS-Gut-EIIA, srlB; PTS system, glucitol/sorbitol-specific IIA component [EC:2.7.1.198]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
qrtT; energy-coupling factor transport system substrate-specific component	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
racD; aspartate racemase [EC:5.1.1.13]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
rgpE; glucosyltransferase [EC:2.4.1.-]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
rstA1; phage replication initiation protein	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
sbcC, rad50; DNA repair protein SbcC/Rad50	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
srlD; sorbitol-6-phosphate 2-dehydrogenase [EC:1.1.1.140]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
TC.SSS; solute:Na+ symporter, SSS family	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
topB; DNA topoisomerase III [EC:5.99.1.2]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
tyrA1; chorismate mutase [EC:5.4.99.5]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
virD4, lvhD4; type IV secretion system protein VirD4	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224
xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22]	0.00004	0.00003	0.00005	0.00000	0.00005	65	0.00004	0.00000	0.00004	93	0.00006	0.04743	146.78	0.96224	0.96224

plot.dat <- tb.ra %>%
  arrange(desc(`Overall Mean`)) %>%
  slice_head(n=50)%>%
  mutate(
    description = fct_reorder(description, `Overall Mean`),
    description = factor(description, levels = levels(description), ordered=T)
  ) %>%
  arrange(description) %>%
  mutate(
    id = 1:n(),
    step = ifelse(id%%2 == 0, 1, 0),
    Mean_diff = `Tumor Mean` - `Non-Tumor Mean`,
    diff_se = SEpooled,
    Mean_diff_ll = Mean_diff - qt(0.975, df)*diff_se,
    Mean_diff_ul = Mean_diff + qt(0.975, df)*diff_se
  ) %>%
  pivot_longer(
    cols=contains("Mean"),
    names_to = "group",
    values_to = "mean"
  )



p1.d <- plot.dat %>%
  filter(group %in% c("Tumor Mean","Non-Tumor Mean")) %>%
  mutate(
    group = ifelse(group == "Tumor Mean", "Tumor", "Non-Tumor"),
    col = ifelse(step == 1, "grey90", "white"),
    h=1, w=Inf
    
  )
p1 <- ggplot()+
  geom_tile(data = p1.d,
              aes(y = description, x=0,
                  height=h, width=w),
              fill = p1.d$col, color=p1.d$col)+
    geom_bar(data=p1.d,
             aes(x=mean, y=description,
                 group=group, color=group,
                 fill=group),
             stat="identity",position = "dodge",
             alpha = 1)+
    labs(x="Mean RelAbundance")+
    theme_classic()+
    theme(
      legend.position = "bottom",
      plot.margin = unit(c(1,0,1,1), "lines")
    )

p2.d <- plot.dat %>%
  filter(group %in% c("Mean_diff", "Mean_diff_ll", "Mean_diff_ul")) %>%
  pivot_wider(
    names_from = group,
    values_from = mean
  ) %>%
  mutate(
    group = ifelse(Mean_diff > 0, "Tumor", "Non-Tumor"),
    p = sprintf("%.3f", round(fdr_p,3)),
    ll = min(Mean_diff_ll)-0.01,
    ul = max(Mean_diff_ul)+0.01
  )
p2<-ggplot(p2.d, aes(x=Mean_diff, y=description))+
    geom_tile(data = p1.d,
              aes(y = description, x=0,
                  height=h, width=w),
              fill = p1.d$col, color=p1.d$col)+
    geom_vline(xintercept = 0, linetype="dashed", alpha=0.5)+
    geom_segment(aes(x=Mean_diff_ll, y=description, xend=Mean_diff_ul, yend=description))+
    geom_point(aes(fill=group, color=group))+
    geom_text(aes(label=p, x=unique(ul)+0.025))+
    coord_cartesian(xlim = c(unique(p2.d$ll), unique(p2.d$ul)),
                    clip = 'off') +
    annotate("text", x=unique(p2.d$ul)+0.05,y = 25,
             angle=90,
             label="q-value (FDR Corrected p-value)")+
    labs(x="Mean Difference in RelAbundance")+
    theme_classic()+
    theme(
      legend.position = "bottom",
      axis.title.y = element_blank(),
      axis.text.y = element_blank(),
      axis.line.y = element_blank(),
      axis.ticks.y = element_blank(),
      plot.margin = unit(c(1,4,1,0), "lines")
    )

# plot
p <- p1 + p2 +
  plot_annotation(title="Stratefied KO Data - Streptococcus sanguinis : 50 most abundant descriptions")
p

ggsave("output/updated-figures-2021-05-20/picrust-strepto-KO.pdf",p,units="in", height=12, width=10)

Modeling Difference between Tumor and Non-Tumor

For the modeling, we used a generalized linear mixed model (GLMM).

First, we looked at the biserial correlation between the abundance of each description and the tumor status.

tb <- mydata %>%
  group_by(description)%>%
  summarise(
    r = cor(tumor, Abundance)
  ) %>%
  mutate(
    M=mean(r)
  )

ggplot(tb, aes(x=r))+
  geom_density()+
  geom_vline(aes(xintercept = M))+
  labs(x="Biserial Correlation",title="Relationship between description abundance and tumor (tumor vs. non-tumor)")+
  theme(panel.grid = element_blank())

Next, we need the data to be on an interpretable scale. First, let’s use the raw abundance like scale.

p <- ggplot(mydata, aes(x=Abundance))+
  geom_density()
p

mydata <- mydata %>%
  mutate(Abundance.dich=ifelse(Abundance==0, 0, 1))
table(mydata$Abundance.dich)


     0      1 
 26243 150243

Let’s first run models by description so that we can avoid the nesting issue initially. We will come back to this to conduct the final model (it will be more powerful).

DESCRIPTIONS <- unique(mydata$description)
i<-1
dat0 <- mydata %>% filter(description==DESCRIPTIONS[i])

# quasipossion (approximately negative binom) give an approx. answer.
fit0 <- glm(
  Abundance ~ 1 + tumor,
  data= dat0,
  family=quasipoisson(link = "log")
)
summary(fit0)


Call:
glm(formula = Abundance ~ 1 + tumor, family = quasipoisson(link = "log"), 
    data = dat0)

Deviance Residuals: 
   Min      1Q  Median      3Q     Max  
 -9.27   -7.88   -3.43    3.93   16.52  

Coefficients:
            Estimate Std. Error t value Pr(>|t|)    
(Intercept)    3.759      0.118   31.92   <2e-16 ***
tumor         -0.126      0.191   -0.66     0.51    
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

(Dispersion parameter for quasipoisson family taken to be 55.387)

    Null deviance: 8252.3  on 157  degrees of freedom
Residual deviance: 8227.9  on 156  degrees of freedom
AIC: NA

Number of Fisher Scoring iterations: 6

NExt, let’s model the percent relative abundance. This will allow us to make inference about the difference average relative abundance. Which is a simpler interpretation than trying to model differences in the log relative abundance which will need to be interpreted as the multiplicative relative change.

results.out <- as.data.frame(matrix(ncol=4, nrow=length(DESCRIPTIONS)))
colnames(results.out) <- c("description", "Est", "SE", "p")
#results.out$description <-DESCRIPTIONS

i <- 1
for(i in 1:length(DESCRIPTIONS)){
#for(i in 1:5){ 
  dat0 <- mydata %>%
    filter(description == DESCRIPTIONS[i])
  fit0 <- glm(
  Abundance ~ 1 + tumor,
  data= dat0,
  family=quasipoisson(link = "log")
)
  fit.sum <- summary(fit0)
  results.out[i, 1] <- DESCRIPTIONS[i]
  results.out[i, 2:4] <- fit.sum$coefficients[2, c(1,2,4)]
}

results.out$fdr_p <- p.adjust(results.out$p, method="fdr")

kable(results.out, format="html", digits=3) %>%
  kable_styling(full_width = T)%>%
  scroll_box(width="100%", height="600px")

description	Est	SE	p	fdr_p
aadK; aminoglycoside 6-adenylyltransferase [EC:2.7.7.-]	-0.126	0.191	0.509	0.566
AARS, alaS; alanyl-tRNA synthetase [EC:6.1.1.7]	-0.126	0.191	0.509	0.566
ABC-2.A; ABC-2 type transport system ATP-binding protein	-0.126	0.191	0.509	0.566
ABC-2.CYL.A, cylA; multidrug/hemolysin transport system ATP-binding protein	-0.126	0.191	0.509	0.566
ABC-2.CYL.P, cylB; multidrug/hemolysin transport system permease protein	-0.126	0.191	0.509	0.566
ABC-2.P; ABC-2 type transport system permease protein	-0.126	0.191	0.509	0.566
ABC.CD.A; putative ABC transport system ATP-binding protein	-0.126	0.191	0.510	0.566
ABC.CD.P; putative ABC transport system permease protein	-0.127	0.191	0.509	0.566
ABC.CD.TX; HlyD family secretion protein	-0.128	0.194	0.510	0.566
ABC.FEV.A; iron complex transport system ATP-binding protein [EC:3.6.3.34]	-0.126	0.191	0.509	0.566
ABC.FEV.P; iron complex transport system permease protein	-0.125	0.191	0.513	0.566
ABC.FEV.S; iron complex transport system substrate-binding protein	-0.124	0.191	0.517	0.566
ABC.GLN1.A; putative glutamine transport system ATP-binding protein [EC:3.6.3.-]	-0.126	0.191	0.510	0.566
ABC.GLN1.P; putative glutamine transport system permease protein	-0.126	0.191	0.510	0.566
ABC.GLN1.S; putative glutamine transport system substrate-binding protein	-0.126	0.191	0.510	0.566
ABC.MS.P; multiple sugar transport system permease protein	-0.124	0.191	0.517	0.566
ABC.MS.P1; multiple sugar transport system permease protein	-0.124	0.191	0.517	0.566
ABC.MS.S; multiple sugar transport system substrate-binding protein	-0.123	0.193	0.523	0.566
ABC.PA.A; polar amino acid transport system ATP-binding protein [EC:3.6.3.21]	-0.125	0.191	0.514	0.566
ABC.PA.P; polar amino acid transport system permease protein	-0.125	0.191	0.514	0.566
ABC.PA.S; polar amino acid transport system substrate-binding protein	-0.125	0.191	0.514	0.566
ABC.PE.S; peptide/nickel transport system substrate-binding protein	-0.125	0.191	0.513	0.566
ABC.SS.A; simple sugar transport system ATP-binding protein [EC:3.6.3.17]	-0.126	0.191	0.509	0.566
ABC.SS.P; simple sugar transport system permease protein	-0.126	0.191	0.509	0.566
ABC.X4.A; putative ABC transport system ATP-binding protein	-0.124	0.191	0.517	0.566
ABC.X4.P; putative ABC transport system permease protein	-0.124	0.191	0.517	0.566
ABC.X4.S; putative ABC transport system substrate-binding protein	-0.124	0.191	0.517	0.566
ABCB-BAC; ATP-binding cassette, subfamily B, bacterial	-0.128	0.193	0.509	0.566
ABCC-BAC; ATP-binding cassette, subfamily C, bacterial	-0.125	0.191	0.513	0.566
ABCF3; ATP-binding cassette, subfamily F, member 3	-0.126	0.191	0.509	0.566
accA; acetyl-CoA carboxylase carboxyl transferase subunit alpha [EC:6.4.1.2 2.1.3.15]	-0.126	0.191	0.510	0.566
accB, bccP; acetyl-CoA carboxylase biotin carboxyl carrier protein	-0.126	0.191	0.509	0.566
accC; acetyl-CoA carboxylase, biotin carboxylase subunit [EC:6.4.1.2 6.3.4.14]	-0.126	0.191	0.509	0.566
accD; acetyl-CoA carboxylase carboxyl transferase subunit beta [EC:6.4.1.2 2.1.3.15]	-0.126	0.191	0.509	0.566
ackA; acetate kinase [EC:2.7.2.1]	-0.126	0.191	0.509	0.566
acm; lysozyme	-0.126	0.191	0.509	0.566
ACO, acnA; aconitate hydratase [EC:4.2.1.3]	-0.133	0.217	0.540	0.566
acpP; acyl carrier protein	-0.126	0.191	0.509	0.566
acpS; holo-[acyl-carrier protein] synthase [EC:2.7.8.7]	-0.126	0.191	0.509	0.566
acrR, smeT; TetR/AcrR family transcriptional regulator, acrAB operon repressor	-0.133	0.217	0.540	0.566
acuB; acetoin utilization protein AcuB	-0.126	0.191	0.509	0.566
acyP; acylphosphatase [EC:3.6.1.7]	-0.126	0.191	0.509	0.566
addA; ATP-dependent helicase/nuclease subunit A [EC:3.1.-.- 3.6.4.12]	-0.126	0.191	0.509	0.566
addB; ATP-dependent helicase/nuclease subunit B [EC:3.1.-.- 3.6.4.12]	-0.126	0.191	0.509	0.566
adh2; alcohol dehydrogenase [EC:1.1.1.-]	-0.121	0.201	0.548	0.566
adhE; acetaldehyde dehydrogenase / alcohol dehydrogenase [EC:1.2.1.10 1.1.1.1]	-0.126	0.191	0.509	0.566
adhP; alcohol dehydrogenase, propanol-preferring [EC:1.1.1.1]	-0.126	0.191	0.509	0.566
adk, AK; adenylate kinase [EC:2.7.4.3]	-0.126	0.191	0.509	0.566
afuA, fbpA; iron(III) transport system substrate-binding protein	-0.121	0.201	0.548	0.566
afuB, fbpB; iron(III) transport system permease protein	-0.121	0.201	0.548	0.566
afuC, fbpC; iron(III) transport system ATP-binding protein [EC:3.6.3.30]	-0.121	0.201	0.548	0.566
agaS; tagatose-6-phosphate ketose/aldose isomerase [EC:5.-.-.-]	-0.126	0.191	0.509	0.566
agrA, blpR, fsrA; two-component system, LytTR family, response regulator AgrA	-0.123	0.194	0.528	0.566
agrC, blpH, fsrC; two-component system, LytTR family, sensor histidine kinase AgrC [EC:2.7.13.3]	-0.123	0.193	0.523	0.566
aguA; agmatine deiminase [EC:3.5.3.12]	-0.121	0.201	0.548	0.566
aguB; N-carbamoylputrescine amidase [EC:3.5.1.53]	-0.121	0.201	0.548	0.566
alaA; alanine-synthesizing transaminase [EC:2.6.1.66 2.6.1.2]	-0.126	0.191	0.509	0.566
ald; alanine dehydrogenase [EC:1.4.1.1]	-0.133	0.217	0.540	0.566
alr; alanine racemase [EC:5.1.1.1]	-0.126	0.191	0.509	0.566
alsD, budA, aldC; acetolactate decarboxylase [EC:4.1.1.5]	-0.126	0.191	0.509	0.566
ampC; beta-lactamase class C [EC:3.5.2.6]	-0.126	0.191	0.509	0.566
ampS, pepS, ampT; aminopeptidase [EC:3.4.11.-]	-0.126	0.191	0.509	0.566
AMY, amyA, malS; alpha-amylase [EC:3.2.1.1]	-0.126	0.191	0.509	0.566
apbE; FAD:protein FMN transferase [EC:2.7.1.180]	-0.126	0.191	0.509	0.566
aphA; kanamycin kinase [EC:2.7.1.95]	-0.133	0.217	0.540	0.566
APRT, apt; adenine phosphoribosyltransferase [EC:2.4.2.7]	-0.126	0.191	0.509	0.566
aqpZ; aquaporin Z	-0.121	0.201	0.547	0.566
arcA; arginine deiminase [EC:3.5.3.6]	-0.133	0.217	0.540	0.566
arcC; carbamate kinase [EC:2.7.2.2]	-0.133	0.217	0.540	0.566
argB; acetylglutamate kinase [EC:2.7.2.8]	-0.133	0.217	0.540	0.566
argC; N-acetyl-gamma-glutamyl-phosphate reductase [EC:1.2.1.38]	-0.133	0.217	0.540	0.566
argG, ASS1; argininosuccinate synthase [EC:6.3.4.5]	-0.133	0.217	0.540	0.566
argH, ASL; argininosuccinate lyase [EC:4.3.2.1]	-0.133	0.217	0.540	0.566
argJ; glutamate N-acetyltransferase / amino-acid N-acetyltransferase [EC:2.3.1.35 2.3.1.1]	-0.133	0.217	0.540	0.566
argR, ahrC; transcriptional regulator of arginine metabolism	-0.126	0.191	0.509	0.566
aroA; 3-phosphoshikimate 1-carboxyvinyltransferase [EC:2.5.1.19]	-0.126	0.191	0.509	0.566
AROA1, aroA; chorismate mutase [EC:5.4.99.5]	-0.126	0.191	0.509	0.566
aroB; 3-dehydroquinate synthase [EC:4.2.3.4]	-0.126	0.191	0.509	0.566
aroC; chorismate synthase [EC:4.2.3.5]	-0.126	0.191	0.509	0.566
aroD; 3-dehydroquinate dehydratase I [EC:4.2.1.10]	-0.126	0.191	0.509	0.566
aroE; shikimate dehydrogenase [EC:1.1.1.25]	-0.126	0.191	0.509	0.566
ARSC1, arsC; arsenate reductase [EC:1.20.4.1]	-0.128	0.194	0.510	0.566
asd; aspartate-semialdehyde dehydrogenase [EC:1.2.1.11]	-0.126	0.191	0.509	0.566
asnA; aspartate–ammonia ligase [EC:6.3.1.1]	-0.121	0.201	0.548	0.566
asp1; accessory secretory protein Asp1	-0.126	0.191	0.509	0.566
asp2; accessory secretory protein Asp2	-0.126	0.191	0.509	0.566
asp3; accessory secretory protein Asp3	-0.126	0.191	0.509	0.566
aspS; aspartyl-tRNA synthetase [EC:6.1.1.12]	-0.128	0.194	0.510	0.566
ATPF0A, atpB; F-type H+-transporting ATPase subunit a	-0.126	0.191	0.509	0.566
ATPF0B, atpF; F-type H+-transporting ATPase subunit b	-0.126	0.191	0.509	0.566
ATPF0C, atpE; F-type H+-transporting ATPase subunit c	-0.126	0.191	0.509	0.566
ATPF1A, atpA; F-type H+-transporting ATPase subunit alpha [EC:3.6.3.14]	-0.126	0.191	0.509	0.566
ATPF1B, atpD; F-type H+-transporting ATPase subunit beta [EC:3.6.3.14]	-0.126	0.191	0.509	0.566
ATPF1D, atpH; F-type H+-transporting ATPase subunit delta	-0.126	0.191	0.509	0.566
ATPF1E, atpC; F-type H+-transporting ATPase subunit epsilon	-0.126	0.191	0.509	0.566
ATPF1G, atpG; F-type H+-transporting ATPase subunit gamma	-0.126	0.191	0.509	0.566
ATPVA, ntpA, atpA; V/A-type H+/Na+-transporting ATPase subunit A [EC:3.6.3.14 3.6.3.15]	-0.133	0.217	0.540	0.566
ATPVB, ntpB, atpB; V/A-type H+/Na+-transporting ATPase subunit B	-0.133	0.217	0.540	0.566
ATPVC, ntpC, atpC; V/A-type H+/Na+-transporting ATPase subunit C	-0.133	0.217	0.540	0.566
ATPVD, ntpD, atpD; V/A-type H+/Na+-transporting ATPase subunit D	-0.133	0.217	0.540	0.566
ATPVE, ntpE, atpE; V/A-type H+/Na+-transporting ATPase subunit E	-0.133	0.217	0.540	0.566
ATPVF, ntpF, atpF; V/A-type H+/Na+-transporting ATPase subunit F	-0.133	0.217	0.540	0.566
ATPVG, ahaH, atpH; V/A-type H+/Na+-transporting ATPase subunit G/H	-0.335	1.544	0.829	0.829
ATPVI, ntpI, atpI; V/A-type H+/Na+-transporting ATPase subunit I	-0.133	0.217	0.540	0.566
ATPVK, ntpK, atpK; V/A-type H+/Na+-transporting ATPase subunit K	-0.133	0.217	0.540	0.566
bacA; undecaprenyl-diphosphatase [EC:3.6.1.27]	-0.126	0.191	0.509	0.566
bcrC; undecaprenyl-diphosphatase [EC:3.6.1.27]	-0.126	0.191	0.509	0.566
BDH, butB; (R,R)-butanediol dehydrogenase / meso-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.4 1.1.1.- 1.1.1.303]	-0.133	0.217	0.540	0.566
bdhAB; butanol dehydrogenase [EC:1.1.1.-]	-0.133	0.217	0.541	0.566
bgaB, lacA; beta-galactosidase [EC:3.2.1.23]	-0.126	0.191	0.509	0.566
bglG1; transcriptional antiterminator	-0.133	0.217	0.541	0.566
bioY; biotin transport system substrate-specific component	-0.126	0.191	0.509	0.566
birA; BirA family transcriptional regulator, biotin operon repressor / biotin—[acetyl-CoA-carboxylase] ligase [EC:6.3.4.15]	-0.126	0.191	0.509	0.566
BLMH, pepC; bleomycin hydrolase [EC:3.4.22.40]	-0.126	0.191	0.509	0.566
bmpA, bmpB, tmpC; basic membrane protein A and related proteins	-0.126	0.191	0.509	0.566
butA, budC; meso-butanediol dehydrogenase / (S,S)-butanediol dehydrogenase / diacetyl reductase [EC:1.1.1.- 1.1.1.76 1.1.1.304]	-0.121	0.201	0.547	0.566
cah; cephalosporin-C deacetylase [EC:3.1.1.41]	-0.121	0.201	0.548	0.566
capA, pgsA; gamma-polyglutamate biosynthesis protein CapA	-0.126	0.191	0.509	0.566
carA, CPA1; carbamoyl-phosphate synthase small subunit [EC:6.3.5.5]	-0.126	0.191	0.509	0.566
carB, CPA2; carbamoyl-phosphate synthase large subunit [EC:6.3.5.5]	-0.126	0.191	0.509	0.566
CARS, cysS; cysteinyl-tRNA synthetase [EC:6.1.1.16]	-0.126	0.191	0.509	0.566
cas1; CRISP-associated protein Cas1	-0.133	0.217	0.541	0.566
cas2; CRISPR-associated protein Cas2	-0.133	0.217	0.541	0.566
cas6; CRISPR-associated endoribonuclease Cas6 [EC:3.1.-.-]	-0.133	0.217	0.541	0.566
catE; catechol 2,3-dioxygenase [EC:1.13.11.2]	-0.126	0.191	0.509	0.566
cbf, cbf1; 3’-5’ exoribonuclease [EC:3.1.-.-]	-0.126	0.191	0.509	0.566
cca; tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-]	-0.126	0.191	0.509	0.566
ccdA; cytochrome c-type biogenesis protein	-0.126	0.191	0.509	0.566
cdd, CDA; cytidine deaminase [EC:3.5.4.5]	-0.126	0.191	0.509	0.566
CHO1, pssA; CDP-diacylglycerol—serine O-phosphatidyltransferase [EC:2.7.8.8]	-0.133	0.217	0.540	0.566
ciaH; two-component system, OmpR family, sensor histidine kinase CiaH [EC:2.7.13.3]	-0.126	0.191	0.509	0.566
ciaR; two-component system, OmpR family, response regulator CiaR	-0.126	0.191	0.509	0.566
cidA; holin-like protein	-0.126	0.191	0.509	0.566
clpC; ATP-dependent Clp protease ATP-binding subunit ClpC	-0.126	0.191	0.509	0.566
clpE; ATP-dependent Clp protease ATP-binding subunit ClpE	-0.126	0.191	0.509	0.566
clpL; ATP-dependent Clp protease ATP-binding subunit ClpL	-0.126	0.191	0.509	0.566
clpP, CLPP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]	-0.126	0.191	0.509	0.566
clpX, CLPX; ATP-dependent Clp protease ATP-binding subunit ClpX	-0.126	0.191	0.509	0.566
clsA_B; cardiolipin synthase A/B [EC:2.7.8.-]	-0.126	0.191	0.509	0.566
cmk; CMP/dCMP kinase [EC:2.7.4.25]	-0.126	0.191	0.509	0.566
cmoA; tRNA (cmo5U34)-methyltransferase [EC:2.1.1.-]	-0.121	0.201	0.548	0.566
coaA; type I pantothenate kinase [EC:2.7.1.33]	-0.126	0.191	0.509	0.566
coaE; dephospho-CoA kinase [EC:2.7.1.24]	-0.126	0.191	0.509	0.566
codY; transcriptional pleiotropic repressor	-0.126	0.191	0.509	0.566
coiA; competence protein CoiA	-0.126	0.191	0.509	0.566
comA; ATP-binding cassette, subfamily C, bacterial, competence factor transporting protein [EC:3.4.22.-]	-0.121	0.201	0.547	0.566
comB; competence factor transport accessory protein ComB	-0.121	0.201	0.547	0.566
comC; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]	-0.126	0.191	0.509	0.566
comD; two-component system, LytTR family, sensor histidine kinase ComD [EC:2.7.13.3]	-0.126	0.191	0.509	0.566
comE; two-component system, LytTR family, response regulator ComE	-0.124	0.191	0.517	0.566
comEA; competence protein ComEA	-0.126	0.191	0.509	0.566
comEB; dCMP deaminase [EC:3.5.4.12]	-0.126	0.191	0.509	0.566
comEC; competence protein ComEC	-0.126	0.191	0.509	0.566
comFA; competence protein ComFA	-0.126	0.191	0.509	0.566
comFC; competence protein ComFC	-0.126	0.191	0.509	0.566
comGA; competence protein ComGA	-0.126	0.191	0.509	0.566
comGB; competence protein ComGB	-0.126	0.191	0.509	0.566
comGC; competence protein ComGC	-0.126	0.191	0.509	0.566
comGD; competence protein ComGD	-0.126	0.191	0.509	0.566
comGF; competence protein ComGF	-0.126	0.191	0.509	0.566
comX1_2; competence protein ComX	-0.124	0.191	0.517	0.566
copA, ATP7; Cu+-exporting ATPase [EC:3.6.3.54]	-0.126	0.191	0.509	0.566
corA; magnesium transporter	-0.126	0.191	0.509	0.566
cotH; spore coat protein H	-0.335	1.544	0.829	0.829
cpdB; 2’,3’-cyclic-nucleotide 2’-phosphodiesterase / 3’-nucleotidase [EC:3.1.4.16 3.1.3.6]	-0.133	0.217	0.541	0.566
cpoA; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-galactosyltransferase [EC:2.4.1.-]	-0.121	0.201	0.548	0.566
crcB, FEX; fluoride exporter	-0.126	0.191	0.509	0.566
CS, gltA; citrate synthase [EC:2.3.3.1]	-0.133	0.217	0.540	0.566
cshB; ATP-dependent RNA helicase CshB [EC:3.6.4.13]	-0.126	0.191	0.509	0.566
csn1, cas9; CRISPR-associated endonuclease Csn1 [EC:3.1.-.-]	-0.133	0.217	0.541	0.566
ctpE; cation-transporting P-type ATPase E [EC:3.6.3.-]	-0.126	0.191	0.509	0.566
ctsR; transcriptional regulator of stress and heat shock response	-0.126	0.191	0.509	0.566
cutC; copper homeostasis protein	-0.126	0.191	0.509	0.566
cycB, ganO; arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein	-0.126	0.191	0.509	0.566
cynT, can; carbonic anhydrase [EC:4.2.1.1]	-0.126	0.191	0.509	0.566
cysE; serine O-acetyltransferase [EC:2.3.1.30]	-0.126	0.191	0.509	0.566
cysK; cysteine synthase A [EC:2.5.1.47]	-0.126	0.191	0.509	0.566
czcD, zitB; cobalt-zinc-cadmium efflux system protein	-0.126	0.191	0.509	0.566
dacA; diadenylate cyclase [EC:2.7.7.85]	-0.126	0.191	0.509	0.566
dacC, dacA, dacD; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]	-0.126	0.191	0.509	0.566
dagK; diacylglycerol kinase (ATP) [EC:2.7.1.107]	-0.133	0.217	0.540	0.566
DAK, TKFC; triose/dihydroxyacetone kinase / FAD-AMP lyase (cyclizing) [EC:2.7.1.28 2.7.1.29 4.6.1.15]	-0.121	0.201	0.548	0.566
dapA; 4-hydroxy-tetrahydrodipicolinate synthase [EC:4.3.3.7]	-0.126	0.191	0.509	0.566
dapB; 4-hydroxy-tetrahydrodipicolinate reductase [EC:1.17.1.8]	-0.128	0.194	0.510	0.566
dapD; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [EC:2.3.1.117]	-0.126	0.191	0.509	0.566
dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]	-0.126	0.191	0.509	0.566
dapL; N-acetyldiaminopimelate deacetylase [EC:3.5.1.47]	-0.126	0.191	0.509	0.566
ddl; D-alanine-D-alanine ligase [EC:6.3.2.4]	-0.124	0.191	0.517	0.566
deaD, cshA; ATP-dependent RNA helicase DeaD [EC:3.6.4.13]	-0.126	0.191	0.509	0.566
degP, htrA; serine protease Do [EC:3.4.21.107]	-0.126	0.191	0.509	0.566
deoB; phosphopentomutase [EC:5.4.2.7]	-0.126	0.191	0.509	0.566
deoC, DERA; deoxyribose-phosphate aldolase [EC:4.1.2.4]	-0.126	0.191	0.509	0.566
deoD; purine-nucleoside phosphorylase [EC:2.4.2.1]	-0.126	0.191	0.509	0.566
desK; two-component system, NarL family, sensor histidine kinase DesK [EC:2.7.13.3]	-0.126	0.191	0.509	0.566
dexB; glucan 1,6-alpha-glucosidase [EC:3.2.1.70]	-0.121	0.201	0.548	0.566
dgkA; undecaprenol kinase [EC:2.7.1.66]	-0.126	0.191	0.509	0.566
dgs, bgsA; 1,2-diacylglycerol-3-alpha-glucose alpha-1,2-glucosyltransferase [EC:2.4.1.208]	-0.133	0.217	0.540	0.566
dhaK; phosphoenolpyruvate—glycerone phosphotransferase subunit DhaK [EC:2.7.1.121]	-0.121	0.201	0.548	0.566
dhaL; phosphoenolpyruvate—glycerone phosphotransferase subunit DhaL [EC:2.7.1.121]	-0.126	0.191	0.510	0.566
DHFR, folA; dihydrofolate reductase [EC:1.5.1.3]	-0.126	0.191	0.509	0.566
dinB; DNA polymerase IV [EC:2.7.7.7]	-0.126	0.191	0.509	0.566
dinG; ATP-dependent DNA helicase DinG [EC:3.6.4.12]	-0.126	0.191	0.509	0.566
dinJ; DNA-damage-inducible protein J	-0.126	0.191	0.509	0.566
divIC, divA; cell division protein DivIC	-0.126	0.191	0.509	0.566
divIVA; cell division initiation protein	-0.126	0.191	0.509	0.566
DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12]	-0.126	0.191	0.509	0.566
DLD, lpd, pdhD; dihydrolipoamide dehydrogenase [EC:1.8.1.4]	-0.126	0.191	0.509	0.566
dltA; D-alanine–poly(phosphoribitol) ligase subunit 1 [EC:6.1.1.13]	-0.126	0.191	0.509	0.566
dltB; membrane protein involved in D-alanine export	-0.126	0.191	0.509	0.566
dltC; D-alanine–poly(phosphoribitol) ligase subunit 2 [EC:6.1.1.13]	-0.126	0.191	0.509	0.566
dltD; D-alanine transfer protein	-0.126	0.191	0.509	0.566
dnaA; chromosomal replication initiator protein	-0.126	0.191	0.509	0.566
dnaB; replication initiation and membrane attachment protein	-0.126	0.191	0.509	0.566
dnaB; replicative DNA helicase [EC:3.6.4.12]	-0.126	0.191	0.509	0.566
dnaD; DNA replication protein	-0.126	0.191	0.509	0.566
dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]	-0.126	0.191	0.509	0.566
dnaG; DNA primase [EC:2.7.7.-]	-0.126	0.191	0.509	0.566
dnaI; primosomal protein DnaI	-0.126	0.191	0.509	0.566
dnaJ; molecular chaperone DnaJ	-0.126	0.191	0.509	0.566
dnaK, HSPA9; molecular chaperone DnaK	-0.126	0.191	0.509	0.566
dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]	-0.126	0.191	0.509	0.566
dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]	-0.121	0.201	0.548	0.566
dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]	-0.126	0.191	0.509	0.566
DNMT1, dcm; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]	-0.121	0.200	0.546	0.566
doc; death on curing protein	-0.121	0.201	0.548	0.566
DPM1; dolichol-phosphate mannosyltransferase [EC:2.4.1.83]	-0.121	0.201	0.548	0.566
dps; starvation-inducible DNA-binding protein	-0.126	0.191	0.509	0.566
dtd, DTD1; D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-]	-0.126	0.191	0.509	0.566
dut, DUT; dUTP pyrophosphatase [EC:3.6.1.23]	-0.126	0.191	0.509	0.566
E1.1.1.1, adh; alcohol dehydrogenase [EC:1.1.1.1]	-0.133	0.217	0.540	0.566
E1.1.1.3; homoserine dehydrogenase [EC:1.1.1.3]	-0.126	0.191	0.509	0.566
E1.1.3.21; alpha-glycerophosphate oxidase [EC:1.1.3.21]	-0.126	0.191	0.509	0.566
E1.17.4.1A, nrdA, nrdE; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]	-0.126	0.191	0.509	0.566
E1.17.4.1B, nrdB, nrdF; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]	-0.126	0.191	0.509	0.566
E1.2.3.3, poxL; pyruvate oxidase [EC:1.2.3.3]	-0.126	0.191	0.509	0.566
E1.4.1.4, gdhA; glutamate dehydrogenase (NADP+) [EC:1.4.1.4]	-0.128	0.194	0.510	0.566
E1.7.1.7, guaC; GMP reductase [EC:1.7.1.7]	-0.126	0.191	0.509	0.566
E2.1.1.72; site-specific DNA-methyltransferase (adenine-specific) [EC:2.1.1.72]	-0.128	0.194	0.510	0.566
E2.2.1.1, tktA, tktB; transketolase [EC:2.2.1.1]	-0.123	0.193	0.524	0.566
E2.2.1.6L, ilvB, ilvG, ilvI; acetolactate synthase I/II/III large subunit [EC:2.2.1.6]	-0.126	0.191	0.509	0.566
E2.2.1.6S, ilvH, ilvN; acetolactate synthase I/III small subunit [EC:2.2.1.6]	-0.126	0.191	0.509	0.566
E2.3.1.54, pflD; formate C-acetyltransferase [EC:2.3.1.54]	-0.128	0.194	0.510	0.566
E2.3.1.8, pta; phosphate acetyltransferase [EC:2.3.1.8]	-0.126	0.191	0.509	0.566
E2.3.3.10; hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10]	-0.126	0.191	0.509	0.566
E2.4.-.-; glycosyltransferase [EC:2.4.-.-]	-0.133	0.217	0.540	0.566
E2.4.1.5; dextransucrase [EC:2.4.1.5]	-0.133	0.217	0.540	0.566
E2.4.1.7; sucrose phosphorylase [EC:2.4.1.7]	-0.133	0.217	0.541	0.566
E2.5.1.54, aroF, aroG, aroH; 3-deoxy-7-phosphoheptulonate synthase [EC:2.5.1.54]	-0.126	0.191	0.510	0.566
E2.6.1.11, argD; acetylornithine aminotransferase [EC:2.6.1.11]	-0.133	0.217	0.539	0.566
E2.6.1.42, ilvE; branched-chain amino acid aminotransferase [EC:2.6.1.42]	-0.126	0.191	0.509	0.566
E2.7.1.36, MVK, mvaK1; mevalonate kinase [EC:2.7.1.36]	-0.126	0.191	0.509	0.566
E2.7.1.4, scrK; fructokinase [EC:2.7.1.4]	-0.133	0.217	0.540	0.566
E2.7.1.71, aroK, aroL; shikimate kinase [EC:2.7.1.71]	-0.126	0.191	0.509	0.566
E2.7.13.3; histidine kinase [EC:2.7.13.3]	-0.121	0.201	0.548	0.566
E2.7.4.2, mvaK2; phosphomevalonate kinase [EC:2.7.4.2]	-0.126	0.191	0.509	0.566
E2.7.4.8, gmk; guanylate kinase [EC:2.7.4.8]	-0.126	0.191	0.509	0.566
E2.7.6.5X; putative GTP pyrophosphokinase [EC:2.7.6.5]	-0.126	0.191	0.509	0.566
E2.7.7.24, rfbA, rffH; glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]	-0.133	0.217	0.540	0.566
E2.7.7.3A, coaD, kdtB; pantetheine-phosphate adenylyltransferase [EC:2.7.7.3]	-0.126	0.191	0.509	0.566
E2.7.7.41, CDS1, CDS2, cdsA; phosphatidate cytidylyltransferase [EC:2.7.7.41]	-0.126	0.191	0.509	0.566
E3.1.11.2, xthA; exodeoxyribonuclease III [EC:3.1.11.2]	-0.126	0.191	0.509	0.566
E3.1.3.15B; histidinol-phosphatase (PHP family) [EC:3.1.3.15]	-0.133	0.217	0.540	0.566
E3.1.3.16; protein phosphatase [EC:3.1.3.16]	-0.126	0.191	0.509	0.566
E3.1.3.25, IMPA, suhB; myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25]	-0.126	0.191	0.509	0.566
E3.1.3.41; 4-nitrophenyl phosphatase [EC:3.1.3.41]	-0.126	0.191	0.509	0.566
E3.1.3.48; protein-tyrosine phosphatase [EC:3.1.3.48]	-0.128	0.194	0.510	0.566
E3.1.3.5; 5’-nucleotidase [EC:3.1.3.5]	-0.133	0.217	0.540	0.566
E3.1.4.46, glpQ, ugpQ; glycerophosphoryl diester phosphodiesterase [EC:3.1.4.46]	-0.126	0.191	0.509	0.566
E3.2.1.22B, galA, rafA; alpha-galactosidase [EC:3.2.1.22]	-0.133	0.217	0.541	0.566
E3.2.1.85, lacG; 6-phospho-beta-galactosidase [EC:3.2.1.85]	-0.126	0.191	0.509	0.566
E3.2.1.86B, bglA; 6-phospho-beta-glucosidase [EC:3.2.1.86]	-0.129	0.198	0.514	0.566
E3.2.1.96; mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [EC:3.2.1.96]	-0.121	0.201	0.548	0.566
E3.4.13.-; D-alanyl-D-alanine dipeptidase [EC:3.4.13.-]	-0.126	0.191	0.509	0.566
E3.4.16.4; D-alanyl-D-alanine carboxypeptidase [EC:3.4.16.4]	-0.133	0.217	0.540	0.566
E3.4.21.96; lactocepin [EC:3.4.21.96]	-0.134	0.217	0.538	0.566
E3.5.1.1, ansA, ansB; L-asparaginase [EC:3.5.1.1]	-0.126	0.191	0.509	0.566
E3.6.3.8; Ca2+-transporting ATPase [EC:3.6.3.8]	-0.126	0.191	0.509	0.566
E4.1.1.18, ldcC, cadA; lysine decarboxylase [EC:4.1.1.18]	-0.121	0.201	0.548	0.566
E4.1.1.19; arginine decarboxylase [EC:4.1.1.19]	-0.121	0.201	0.548	0.566
E4.1.1.49, pckA; phosphoenolpyruvate carboxykinase (ATP) [EC:4.1.1.49]	-0.133	0.217	0.541	0.566
E4.1.3.3, nanA, NPL; N-acetylneuraminate lyase [EC:4.1.3.3]	-0.126	0.191	0.509	0.566
E4.2.1.46, rfbB, rffG; dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]	-0.133	0.217	0.540	0.566
E4.3.1.17, sdaA, sdaB, tdcG; L-serine dehydratase [EC:4.3.1.17]	-0.126	0.191	0.509	0.566
E4.3.1.19, ilvA, tdcB; threonine dehydratase [EC:4.3.1.19]	-0.126	0.191	0.509	0.566
E4.3.1.4; formiminotetrahydrofolate cyclodeaminase [EC:4.3.1.4]	-0.133	0.217	0.540	0.566
E4.6.1.1B, cyaB; adenylate cyclase, class 2 [EC:4.6.1.1]	-0.121	0.201	0.548	0.566
E5.3.1.26, lacA, lacB; galactose-6-phosphate isomerase [EC:5.3.1.26]	-0.124	0.191	0.517	0.566
E6.5.1.2, ligA, ligB; DNA ligase (NAD+) [EC:6.5.1.2]	-0.126	0.191	0.509	0.566
ecfA1; energy-coupling factor transport system ATP-binding protein [EC:3.6.3.-]	-0.126	0.191	0.509	0.566
ecfA2; energy-coupling factor transport system ATP-binding protein [EC:3.6.3.-]	-0.125	0.191	0.513	0.566
ecfT; energy-coupling factor transport system permease protein	-0.125	0.191	0.512	0.566
efeB; deferrochelatase/peroxidase EfeB [EC:1.11.1.-]	-0.133	0.217	0.540	0.566
efeO; iron uptake system component EfeO	-0.133	0.217	0.540	0.566
efp; elongation factor P	-0.126	0.191	0.509	0.566
efrA; ATP-binding cassette, subfamily B, multidrug efflux pump	-0.133	0.217	0.540	0.566
efrB; ATP-binding cassette, subfamily B, multidrug efflux pump	-0.133	0.217	0.540	0.566
elaA; ElaA protein	-0.133	0.217	0.540	0.566
emrE, qac, mmr, smr; small multidrug resistance pump	-0.335	1.544	0.829	0.829
endA; DNA-entry nuclease	-0.126	0.191	0.509	0.566
engA, der; GTPase	-0.126	0.191	0.509	0.566
engB; GTP-binding protein	-0.126	0.191	0.509	0.566
ENO, eno; enolase [EC:4.2.1.11]	-0.126	0.191	0.509	0.566
era, ERAL1; GTPase	-0.126	0.191	0.509	0.566
estA; putative tributyrin esterase [EC:3.1.1.-]	-0.126	0.191	0.509	0.566
eta; exfoliative toxin A/B	-0.126	0.191	0.509	0.566
ezrA; septation ring formation regulator	-0.126	0.191	0.509	0.566
fabD; [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39]	-0.126	0.191	0.509	0.566
fabF; 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179]	-0.126	0.191	0.509	0.566
fabG; 3-oxoacyl-[acyl-carrier protein] reductase [EC:1.1.1.100]	-0.126	0.191	0.509	0.566
fabH; 3-oxoacyl-[acyl-carrier-protein] synthase III [EC:2.3.1.180]	-0.126	0.191	0.509	0.566
fabK; enoyl-[acyl-carrier protein] reductase II [EC:1.3.1.9]	-0.126	0.191	0.509	0.566
fabM; trans-2-decenoyl-[acyl-carrier protein] isomerase [EC:5.3.3.14]	-0.126	0.191	0.509	0.566
fabZ; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase [EC:4.2.1.59]	-0.126	0.191	0.509	0.566
FARSA, pheS; phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20]	-0.126	0.191	0.509	0.566
FARSB, pheT; phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20]	-0.126	0.191	0.509	0.566
FBA, fbaA; fructose-bisphosphate aldolase, class II [EC:4.1.2.13]	-0.126	0.191	0.509	0.566
fbp3; fructose-1,6-bisphosphatase III [EC:3.1.3.11]	-0.133	0.217	0.541	0.566
fctD; glutamate formiminotransferase [EC:2.1.2.5]	-0.133	0.217	0.540	0.566
fer; ferredoxin	-0.126	0.191	0.509	0.566
fhs; formate–tetrahydrofolate ligase [EC:6.3.4.3]	-0.128	0.194	0.510	0.566
flA; adenosyl-fluoride synthase [EC:2.5.1.63]	-0.126	0.191	0.509	0.566
FLOT; flotillin	-0.133	0.217	0.540	0.566
folC; dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]	-0.126	0.191	0.509	0.566
folD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.5 3.5.4.9]	-0.126	0.191	0.509	0.566
folP; dihydropteroate synthase [EC:2.5.1.15]	-0.126	0.191	0.509	0.566
frr, MRRF, RRF; ribosome recycling factor	-0.126	0.191	0.509	0.566
fruA; fructan beta-fructosidase [EC:3.2.1.80]	-0.133	0.217	0.540	0.566
fruK; 1-phosphofructokinase [EC:2.7.1.56]	-0.126	0.191	0.509	0.566
fruR2, fruR; DeoR family transcriptional regulator, fructose operon transcriptional repressor	-0.126	0.191	0.509	0.566
FTR, FTH1, efeU; high-affinity iron transporter	-0.133	0.217	0.540	0.566
ftsA; cell division protein FtsA	-0.126	0.191	0.509	0.566
ftsE; cell division transport system ATP-binding protein	-0.126	0.191	0.509	0.566
ftsH, hflB; cell division protease FtsH [EC:3.4.24.-]	-0.126	0.191	0.509	0.566
ftsK, spoIIIE; DNA segregation ATPase FtsK/SpoIIIE, S-DNA-T family	-0.128	0.194	0.510	0.566
ftsQ; cell division protein FtsQ	-0.126	0.191	0.509	0.566
ftsW, spoVE; cell division protein FtsW	-0.126	0.191	0.509	0.566
ftsX; cell division transport system permease protein	-0.126	0.191	0.509	0.566
ftsY; fused signal recognition particle receptor	-0.126	0.191	0.509	0.566
ftsZ; cell division protein FtsZ	-0.126	0.191	0.509	0.566
FUCA; alpha-L-fucosidase [EC:3.2.1.51]	-0.121	0.200	0.546	0.566
fusA, GFM, EFG; elongation factor G	-0.126	0.191	0.509	0.566
G6PD, zwf; glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49 1.1.1.363]	-0.126	0.191	0.509	0.566
galE, GALE; UDP-glucose 4-epimerase [EC:5.1.3.2]	-0.126	0.191	0.509	0.566
galK; galactokinase [EC:2.7.1.6]	-0.126	0.191	0.509	0.566
galM, GALM; aldose 1-epimerase [EC:5.1.3.3]	-0.126	0.191	0.509	0.566
galT, GALT; UDPglucose–hexose-1-phosphate uridylyltransferase [EC:2.7.7.12]	-0.126	0.191	0.509	0.566
ganP; arabinogalactan oligomer / maltooligosaccharide transport system permease protein	-0.124	0.191	0.517	0.566
ganQ; arabinogalactan oligomer / maltooligosaccharide transport system permease protein	-0.126	0.191	0.509	0.566
GAPDH, gapA; glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12]	-0.126	0.191	0.509	0.566
gapN; glyceraldehyde-3-phosphate dehydrogenase (NADP+) [EC:1.2.1.9]	-0.133	0.217	0.541	0.566
gatA, QRSL1; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7]	-0.126	0.191	0.509	0.566
gatB, PET112; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7]	-0.126	0.191	0.509	0.566
gatC, GATC; aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit C [EC:6.3.5.6 6.3.5.7]	-0.126	0.191	0.509	0.566
GBE1, glgB; 1,4-alpha-glucan branching enzyme [EC:2.4.1.18]	-0.126	0.191	0.509	0.566
GCH1, folE; GTP cyclohydrolase IA [EC:3.5.4.16]	-0.126	0.191	0.509	0.566
GGPS; geranylgeranyl diphosphate synthase, type II [EC:2.5.1.1 2.5.1.10 2.5.1.29]	-0.126	0.191	0.509	0.566
gidA, mnmG, MTO1; tRNA uridine 5-carboxymethylaminomethyl modification enzyme	-0.126	0.191	0.509	0.566
gidB, rsmG; 16S rRNA (guanine527-N7)-methyltransferase [EC:2.1.1.170]	-0.126	0.191	0.509	0.566
gldA; glycerol dehydrogenase [EC:1.1.1.6]	-0.133	0.217	0.541	0.566
glf; UDP-galactopyranose mutase [EC:5.4.99.9]	-0.335	1.544	0.829	0.829
glgA; starch synthase [EC:2.4.1.21]	-0.126	0.191	0.509	0.566
glgC; glucose-1-phosphate adenylyltransferase [EC:2.7.7.27]	-0.126	0.191	0.509	0.566
glk; glucokinase [EC:2.7.1.2]	-0.126	0.191	0.509	0.566
glmM; phosphoglucosamine mutase [EC:5.4.2.10]	-0.126	0.191	0.509	0.566
glmS, GFPT; glucosamine—fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16]	-0.126	0.191	0.509	0.566
glmU; bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase [EC:2.7.7.23 2.3.1.157]	-0.126	0.191	0.509	0.566
glnA, GLUL; glutamine synthetase [EC:6.3.1.2]	-0.126	0.191	0.509	0.566
glnR; MerR family transcriptional regulator, glutamine synthetase repressor	-0.126	0.191	0.509	0.566
GLO1, gloA; lactoylglutathione lyase [EC:4.4.1.5]	-0.126	0.191	0.509	0.566
gloB, HAGH; hydroxyacylglutathione hydrolase [EC:3.1.2.6]	-0.335	1.544	0.829	0.829
GLPF; glycerol uptake facilitator protein	-0.126	0.191	0.509	0.566
glpK, GK; glycerol kinase [EC:2.7.1.30]	-0.126	0.191	0.509	0.566
gltP, gltT; proton glutamate symport protein	-0.133	0.217	0.540	0.566
gltX; nondiscriminating glutamyl-tRNA synthetase [EC:6.1.1.24]	-0.126	0.191	0.509	0.566
glxK, garK; glycerate 2-kinase [EC:2.7.1.165]	-0.126	0.191	0.509	0.566
glyA, SHMT; glycine hydroxymethyltransferase [EC:2.1.2.1]	-0.126	0.191	0.509	0.566
glyQ; glycyl-tRNA synthetase alpha chain [EC:6.1.1.14]	-0.126	0.191	0.509	0.566
glyS; glycyl-tRNA synthetase beta chain [EC:6.1.1.14]	-0.126	0.191	0.509	0.566
gph; phosphoglycolate phosphatase [EC:3.1.3.18]	-0.126	0.191	0.509	0.566
GPI, pgi; glucose-6-phosphate isomerase [EC:5.3.1.9]	-0.126	0.191	0.509	0.566
gpmB; probable phosphoglycerate mutase [EC:5.4.2.12]	-0.129	0.196	0.512	0.566
gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC:1.1.1.94]	-0.126	0.191	0.509	0.566
gpx; glutathione peroxidase [EC:1.11.1.9]	-0.126	0.191	0.509	0.566
greA; transcription elongation factor GreA	-0.126	0.191	0.509	0.566
groEL, HSPD1; chaperonin GroEL	-0.126	0.191	0.509	0.566
groES, HSPE1; chaperonin GroES	-0.126	0.191	0.509	0.566
GRPE; molecular chaperone GrpE	-0.126	0.191	0.509	0.566
gshA; glutamate–cysteine ligase [EC:6.3.2.2]	-0.133	0.217	0.540	0.566
GSP13; general stress protein 13	-0.126	0.191	0.509	0.566
GSR, gor; glutathione reductase (NADPH) [EC:1.8.1.7]	-0.126	0.191	0.509	0.566
guaA, GMPS; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]	-0.126	0.191	0.509	0.566
gyrA; DNA gyrase subunit A [EC:5.99.1.3]	-0.126	0.191	0.509	0.566
gyrB; DNA gyrase subunit B [EC:5.99.1.3]	-0.126	0.191	0.509	0.566
HARS, hisS; histidyl-tRNA synthetase [EC:6.1.1.21]	-0.126	0.191	0.509	0.566
hemE, UROD; uroporphyrinogen decarboxylase [EC:4.1.1.37]	-0.121	0.201	0.548	0.566
hemH, FECH; protoporphyrin/coproporphyrin ferrochelatase [EC:4.99.1.1 4.99.1.9]	-0.126	0.191	0.509	0.566
hemK, prmC, HEMK; release factor glutamine methyltransferase [EC:2.1.1.297]	-0.126	0.191	0.509	0.566
hemN, hemZ; oxygen-independent coproporphyrinogen III oxidase [EC:1.3.98.3]	-0.126	0.191	0.509	0.566
HEXA_B; hexosaminidase [EC:3.2.1.52]	-0.133	0.217	0.539	0.566
hflX; GTPase	-0.126	0.191	0.509	0.566
higB-1; toxin HigB-1	-0.133	0.217	0.541	0.566
HINT1, hinT, hit; histidine triad (HIT) family protein	-0.126	0.191	0.509	0.566
hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [EC:5.3.1.16]	-0.133	0.217	0.540	0.566
hisB; imidazoleglycerol-phosphate dehydratase [EC:4.2.1.19]	-0.133	0.217	0.540	0.566
hisC; histidinol-phosphate aminotransferase [EC:2.6.1.9]	-0.133	0.217	0.540	0.566
hisD; histidinol dehydrogenase [EC:1.1.1.23]	-0.133	0.217	0.540	0.566
hisE; phosphoribosyl-ATP pyrophosphohydrolase [EC:3.6.1.31]	-0.133	0.217	0.540	0.566
hisF; cyclase [EC:4.1.3.-]	-0.133	0.217	0.540	0.566
hisG; ATP phosphoribosyltransferase [EC:2.4.2.17]	-0.133	0.217	0.540	0.566
hisH; glutamine amidotransferase [EC:2.4.2.-]	-0.133	0.217	0.540	0.566
hisI; phosphoribosyl-AMP cyclohydrolase [EC:3.5.4.19]	-0.133	0.217	0.540	0.566
hisZ; ATP phosphoribosyltransferase regulatory subunit	-0.133	0.217	0.540	0.566
hlyIII; hemolysin III	-0.126	0.191	0.509	0.566
holA; DNA polymerase III subunit delta [EC:2.7.7.7]	-0.126	0.191	0.509	0.566
holB; DNA polymerase III subunit delta’ [EC:2.7.7.7]	-0.126	0.191	0.509	0.566
hprK, ptsK; HPr kinase/phosphorylase [EC:2.7.11.- 2.7.4.-]	-0.126	0.191	0.509	0.566
hprT, hpt, HPRT1; hypoxanthine phosphoribosyltransferase [EC:2.4.2.8]	-0.126	0.191	0.509	0.566
hrcA; heat-inducible transcriptional repressor	-0.126	0.191	0.509	0.566
hsdM; type I restriction enzyme M protein [EC:2.1.1.72]	-0.128	0.194	0.511	0.566
hsdR; type I restriction enzyme, R subunit [EC:3.1.21.3]	-0.128	0.194	0.511	0.566
hsdS; type I restriction enzyme, S subunit [EC:3.1.21.3]	-0.127	0.192	0.509	0.566
hslO; molecular chaperone Hsp33	-0.126	0.191	0.509	0.566
htpX; heat shock protein HtpX [EC:3.4.24.-]	-0.126	0.191	0.509	0.566
htsT; energy-coupling factor transport system substrate-specific component	-0.126	0.191	0.509	0.566
hupB; DNA-binding protein HU-beta	-0.126	0.191	0.509	0.566
hutG; formiminoglutamase [EC:3.5.3.8]	-0.133	0.217	0.540	0.566
hutH, HAL; histidine ammonia-lyase [EC:4.3.1.3]	-0.133	0.217	0.540	0.566
hutI, AMDHD1; imidazolonepropionase [EC:3.5.2.7]	-0.133	0.217	0.540	0.566
hutU, UROC1; urocanate hydratase [EC:4.2.1.49]	-0.133	0.217	0.540	0.566
IARS, ileS; isoleucyl-tRNA synthetase [EC:6.1.1.5]	-0.126	0.191	0.509	0.566
IDH1, IDH2, icd; isocitrate dehydrogenase [EC:1.1.1.42]	-0.133	0.217	0.540	0.566
idi, IDI; isopentenyl-diphosphate Delta-isomerase [EC:5.3.3.2]	-0.126	0.191	0.509	0.566
ihk; two-component system, OmpR family, sensor kinase Ihk [EC:2.7.13.3]	-0.133	0.217	0.540	0.566
ilvC; ketol-acid reductoisomerase [EC:1.1.1.86]	-0.126	0.191	0.509	0.566
ilvD; dihydroxy-acid dehydratase [EC:4.2.1.9]	-0.126	0.191	0.509	0.566
IMPDH, guaB; IMP dehydrogenase [EC:1.1.1.205]	-0.126	0.191	0.509	0.566
infA; translation initiation factor IF-1	-0.126	0.191	0.509	0.566
infB, MTIF2; translation initiation factor IF-2	-0.126	0.191	0.509	0.566
infC, MTIF3; translation initiation factor IF-3	-0.126	0.191	0.509	0.566
INV, sacA; beta-fructofuranosidase [EC:3.2.1.26]	-0.126	0.191	0.509	0.566
irr; two-component system, OmpR family, response regulator Irr	-0.133	0.217	0.540	0.566
iscS, NFS1; cysteine desulfurase [EC:2.8.1.7]	-0.126	0.191	0.509	0.566
iscU, nifU; nitrogen fixation protein NifU and related proteins	-0.126	0.191	0.509	0.566
ispD; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [EC:2.7.7.60]	-0.121	0.201	0.548	0.566
jag; spoIIIJ-associated protein	-0.126	0.191	0.509	0.566
K00243; uncharacterized protein	-0.126	0.191	0.509	0.566
K01436; amidohydrolase [EC:3.5.1.-]	-0.133	0.217	0.540	0.566
K03710; GntR family transcriptional regulator	-0.126	0.191	0.509	0.566
K06871; uncharacterized protein	-0.133	0.217	0.541	0.566
K06878; tRNA-binding protein	-0.126	0.191	0.509	0.566
K06885; uncharacterized protein	-0.126	0.191	0.509	0.566
K06889; uncharacterized protein	-0.133	0.217	0.540	0.566
K06890; uncharacterized protein	-0.126	0.191	0.509	0.566
K06915; uncharacterized protein	-0.121	0.201	0.548	0.566
K06929; uncharacterized protein	-0.126	0.191	0.509	0.566
K06940; uncharacterized protein	-0.126	0.191	0.509	0.566
K06950; uncharacterized protein	-0.133	0.217	0.540	0.566
K06960; uncharacterized protein	-0.126	0.191	0.509	0.566
K06962; uncharacterized protein	-0.133	0.217	0.541	0.566
K07004; uncharacterized protein	-0.133	0.217	0.540	0.566
K07007; uncharacterized protein	-0.124	0.191	0.517	0.566
K07009; uncharacterized protein	-0.126	0.191	0.509	0.566
K07010; putative glutamine amidotransferase	-0.126	0.191	0.510	0.566
K07015; uncharacterized protein	-0.126	0.191	0.509	0.566
K07023; putative hydrolases of HD superfamily	-0.133	0.217	0.540	0.566
K07025; putative hydrolase of the HAD superfamily	-0.129	0.198	0.514	0.566
K07030; uncharacterized protein	-0.126	0.191	0.509	0.566
K07040; uncharacterized protein	-0.126	0.191	0.509	0.566
K07052; uncharacterized protein	-0.126	0.191	0.510	0.566
K07054; uncharacterized protein	-0.335	1.544	0.829	0.829
K07058; membrane protein	-0.126	0.191	0.509	0.566
K07078; uncharacterized protein	-0.335	1.544	0.829	0.829
K07082; UPF0755 protein	-0.126	0.191	0.509	0.566
K07088; uncharacterized protein	-0.335	1.544	0.829	0.829
K07089; uncharacterized protein	-0.126	0.191	0.509	0.566
K07095; uncharacterized protein	-0.126	0.191	0.509	0.566
K07105; uncharacterized protein	-0.126	0.191	0.509	0.566
K07124; uncharacterized protein	-0.126	0.191	0.509	0.566
K07133; uncharacterized protein	-0.121	0.201	0.548	0.566
K07139; uncharacterized protein	-0.126	0.191	0.509	0.566
K07146; UPF0176 protein	-0.126	0.191	0.509	0.566
K07166; ACT domain-containing protein	-0.126	0.191	0.509	0.566
K07177; Lon-like protease	-0.126	0.191	0.509	0.566
K07461; putative endonuclease	-0.126	0.191	0.509	0.566
K07485; transposase	-0.121	0.201	0.547	0.566
K07491; putative transposase	-0.121	0.201	0.548	0.566
K07498; putative transposase	-0.335	1.544	0.829	0.829
K07727; putative transcriptional regulator	-0.133	0.217	0.540	0.566
K07729; putative transcriptional regulator	-0.128	0.193	0.509	0.566
K08303; putative protease [EC:3.4.-.-]	-0.126	0.191	0.509	0.566
K08884; serine/threonine protein kinase, bacterial [EC:2.7.11.1]	-0.126	0.191	0.509	0.566
K08974; putative membrane protein	-0.126	0.191	0.509	0.566
K08987; putative membrane protein	-0.126	0.191	0.509	0.566
K08998; uncharacterized protein	-0.126	0.191	0.509	0.566
K09153; uncharacterized protein	-0.133	0.217	0.540	0.566
K09155; uncharacterized protein	-0.126	0.191	0.509	0.566
K09157; uncharacterized protein	-0.126	0.191	0.509	0.566
K09384; uncharacterized protein	-0.335	1.544	0.829	0.829
K09704; uncharacterized protein	-0.121	0.201	0.547	0.566
K09747; uncharacterized protein	-0.126	0.191	0.509	0.566
K09762; uncharacterized protein	-0.126	0.191	0.509	0.566
K09787; uncharacterized protein	-0.126	0.191	0.509	0.566
K09790; uncharacterized protein	-0.126	0.191	0.509	0.566
K09861; uncharacterized protein	-0.126	0.191	0.509	0.566
K09962; uncharacterized protein	-0.126	0.191	0.509	0.566
K09976; uncharacterized protein	-0.126	0.191	0.509	0.566
K10120, msmE; fructooligosaccharide transport system substrate-binding protein	-0.335	1.544	0.829	0.829
K10121, msmF; fructooligosaccharide transport system permease protein	-0.335	1.544	0.829	0.829
K10122, msmG; fructooligosaccharide transport system permease protein	-0.335	1.544	0.829	0.829
K11145; ribonuclease III family protein [EC:3.1.26.-]	-0.126	0.191	0.509	0.566
K13653; AraC family transcriptional regulator	-0.133	0.217	0.540	0.566
K17076, lysY; putative lysine transport system ATP-binding protein [EC:3.6.3.-]	-0.126	0.191	0.509	0.566
K17318, lplA; putative aldouronate transport system substrate-binding protein	-0.124	0.191	0.517	0.566
KAE1, tsaD, QRI7; N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234]	-0.128	0.194	0.510	0.566
KARS, lysS; lysyl-tRNA synthetase, class II [EC:6.1.1.6]	-0.126	0.191	0.509	0.566
kch, trkA, mthK, pch; voltage-gated potassium channel	-0.126	0.191	0.509	0.566
ksgA; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase [EC:2.1.1.182]	-0.126	0.191	0.509	0.566
lacC; tagatose 6-phosphate kinase [EC:2.7.1.144]	-0.126	0.191	0.509	0.566
lacD; tagatose 1,6-diphosphate aldolase [EC:4.1.2.40]	-0.126	0.191	0.509	0.566
lacI, galR; LacI family transcriptional regulator	-0.126	0.191	0.509	0.566
lacR; DeoR family transcriptional regulator, lactose phosphotransferase system repressor	-0.128	0.194	0.510	0.566
lacT; transcriptional antiterminator	-0.126	0.191	0.509	0.566
lacY; MFS transporter, OHS family, lactose permease	-0.133	0.217	0.540	0.566
lacZ; beta-galactosidase [EC:3.2.1.23]	-0.133	0.217	0.540	0.566
LARS, leuS; leucyl-tRNA synthetase [EC:6.1.1.4]	-0.126	0.191	0.509	0.566
lctO; L-lactate oxidase [EC:1.1.3.2]	-0.121	0.201	0.547	0.566
LDH, ldh; L-lactate dehydrogenase [EC:1.1.1.27]	-0.126	0.191	0.509	0.566
lemA; LemA protein	-0.126	0.191	0.509	0.566
lepA; GTP-binding protein LepA	-0.126	0.191	0.509	0.566
lepB; signal peptidase I [EC:3.4.21.89]	-0.128	0.194	0.510	0.566
leuA, IMS; 2-isopropylmalate synthase [EC:2.3.3.13]	-0.126	0.191	0.509	0.566
leuB, IMDH; 3-isopropylmalate dehydrogenase [EC:1.1.1.85]	-0.126	0.191	0.509	0.566
leuC, IPMI-L; 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]	-0.126	0.191	0.509	0.566
leuD, IPMI-S; 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit [EC:4.2.1.33 4.2.1.35]	-0.126	0.191	0.509	0.566
lgt, umpA; phosphatidylglycerol:prolipoprotein diacylglycerol transferase [EC:2.-.-.-]	-0.126	0.191	0.509	0.566
liaR; two-component system, NarL family, response regulator LiaR	-0.126	0.191	0.509	0.566
liaS; two-component system, NarL family, sensor histidine kinase LiaS [EC:2.7.13.3]	-0.126	0.191	0.509	0.566
licD; lipopolysaccharide cholinephosphotransferase [EC:2.7.8.-]	-0.121	0.201	0.548	0.566
licR; lichenan operon transcriptional antiterminator	-0.133	0.217	0.540	0.566
licT, bglG; beta-glucoside operon transcriptional antiterminator	-0.133	0.217	0.540	0.566
livF; branched-chain amino acid transport system ATP-binding protein	-0.126	0.191	0.509	0.566
livG; branched-chain amino acid transport system ATP-binding protein	-0.126	0.191	0.509	0.566
livH; branched-chain amino acid transport system permease protein	-0.126	0.191	0.509	0.566
livK; branched-chain amino acid transport system substrate-binding protein	-0.126	0.191	0.509	0.566
livM; branched-chain amino acid transport system permease protein	-0.126	0.191	0.509	0.566
lplA, lplJ; lipoate—protein ligase [EC:6.3.1.20]	-0.126	0.191	0.509	0.566
lplB; putative aldouronate transport system permease protein	-0.124	0.191	0.517	0.566
lplC; putative aldouronate transport system permease protein	-0.124	0.191	0.517	0.566
lspA; signal peptidase II [EC:3.4.23.36]	-0.126	0.191	0.509	0.566
ltaE; threonine aldolase [EC:4.1.2.48]	-0.335	1.544	0.829	0.829
ltaS; lipoteichoic acid synthase [EC:2.7.8.20]	-0.133	0.217	0.540	0.566
luxS; S-ribosylhomocysteine lyase [EC:4.4.1.21]	-0.126	0.191	0.509	0.566
LYS1; saccharopine dehydrogenase (NAD+, L-lysine forming) [EC:1.5.1.7]	-0.121	0.201	0.548	0.566
lysA; diaminopimelate decarboxylase [EC:4.1.1.20]	-0.126	0.191	0.509	0.566
lysC; aspartate kinase [EC:2.7.2.4]	-0.126	0.191	0.509	0.566
lysX2; putative lysine transport system permease protein	-0.126	0.191	0.509	0.566
maa; maltose O-acetyltransferase [EC:2.3.1.79]	-0.126	0.191	0.509	0.566
malQ; 4-alpha-glucanotransferase [EC:2.4.1.25]	-0.126	0.191	0.509	0.566
MAN2C1; alpha-mannosidase [EC:3.2.1.24]	-0.121	0.201	0.547	0.566
manA, MPI; mannose-6-phosphate isomerase [EC:5.3.1.8]	-0.126	0.191	0.509	0.566
map; methionyl aminopeptidase [EC:3.4.11.18]	-0.126	0.191	0.509	0.566
mapP; maltose 6’-phosphate phosphatase [EC:3.1.3.90]	-0.126	0.191	0.509	0.566
MARS, metG; methionyl-tRNA synthetase [EC:6.1.1.10]	-0.126	0.191	0.509	0.566
MCH; medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21]	-0.126	0.191	0.509	0.566
ME2, sfcA, maeA; malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]	-0.335	1.544	0.829	0.829
mecA1_2; adapter protein MecA 1/2	-0.126	0.191	0.509	0.566
metA; homoserine O-succinyltransferase/O-acetyltransferase [EC:2.3.1.46 2.3.1.31]	-0.126	0.191	0.509	0.566
metB; cystathionine gamma-synthase [EC:2.5.1.48]	-0.126	0.191	0.509	0.566
metE; 5-methyltetrahydropteroyltriglutamate–homocysteine methyltransferase [EC:2.1.1.14]	-0.126	0.191	0.509	0.566
metF, MTHFR; methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20]	-0.126	0.191	0.509	0.566
metI; D-methionine transport system permease protein	-0.124	0.191	0.517	0.566
metK; S-adenosylmethionine synthetase [EC:2.5.1.6]	-0.126	0.191	0.509	0.566
metN; D-methionine transport system ATP-binding protein	-0.126	0.191	0.509	0.566
metQ; D-methionine transport system substrate-binding protein	-0.126	0.191	0.509	0.566
metY; O-acetylhomoserine (thiol)-lyase [EC:2.5.1.49]	-0.126	0.191	0.509	0.566
mfd; transcription-repair coupling factor (superfamily II helicase) [EC:3.6.4.-]	-0.126	0.191	0.509	0.566
MFS.CP; MFS transporter, CP family, cyanate transporter	-0.126	0.191	0.509	0.566
mgs, bgsB; 1,2-diacylglycerol 3-alpha-glucosyltransferase [EC:2.4.1.337]	-0.126	0.191	0.509	0.566
mgtA, mgtB; Mg2+-importing ATPase [EC:3.6.3.2]	-0.126	0.191	0.509	0.566
miaA, TRIT1; tRNA dimethylallyltransferase [EC:2.5.1.75]	-0.126	0.191	0.509	0.566
mmr; MFS transporter, DHA2 family, methylenomycin A resistance protein	-0.121	0.201	0.548	0.566
mmuM, BHMT2; homocysteine S-methyltransferase [EC:2.1.1.10]	-0.133	0.217	0.541	0.566
mnmA, trmU; tRNA-uridine 2-sulfurtransferase [EC:2.8.1.13]	-0.126	0.191	0.509	0.566
mnmE, trmE, MSS1; tRNA modification GTPase [EC:3.6.-.-]	-0.126	0.191	0.509	0.566
mntH; manganese transport protein	-0.335	1.544	0.829	0.829
mraW, rsmH; 16S rRNA (cytosine1402-N4)-methyltransferase [EC:2.1.1.199]	-0.126	0.191	0.509	0.566
mraY; phospho-N-acetylmuramoyl-pentapeptide-transferase [EC:2.7.8.13]	-0.126	0.191	0.509	0.566
mrcA; penicillin-binding protein 1A [EC:2.4.1.129 3.4.16.4]	-0.126	0.191	0.509	0.566
mreC; rod shape-determining protein MreC	-0.126	0.191	0.509	0.566
mreD; rod shape-determining protein MreD	-0.126	0.191	0.509	0.566
mscL; large conductance mechanosensitive channel	-0.126	0.191	0.509	0.566
mscS; small conductance mechanosensitive channel	-0.126	0.191	0.509	0.566
msmE; raffinose/stachyose/melibiose transport system substrate-binding protein	-0.133	0.217	0.541	0.566
msmF; raffinose/stachyose/melibiose transport system permease protein	-0.133	0.217	0.541	0.566
msmG; raffinose/stachyose/melibiose transport system permease protein	-0.133	0.217	0.541	0.566
msmX, msmK, malK, sugC, ggtA, msiK; multiple sugar transport system ATP-binding protein	-0.128	0.194	0.510	0.566
msrAB; peptide methionine sulfoxide reductase msrA/msrB [EC:1.8.4.11 1.8.4.12]	-0.126	0.191	0.509	0.566
mtaD; 5-methylthioadenosine/S-adenosylhomocysteine deaminase [EC:3.5.4.31 3.5.4.28]	-0.126	0.191	0.509	0.566
MTFMT, fmt; methionyl-tRNA formyltransferase [EC:2.1.2.9]	-0.126	0.191	0.509	0.566
MTHFS; 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2]	-0.126	0.191	0.509	0.566
mtnN, mtn, pfs; adenosylhomocysteine nucleosidase [EC:3.2.2.9]	-0.126	0.191	0.509	0.566
mtsA; iron/zinc/manganese/copper transport system substrate-binding protein	-0.126	0.191	0.509	0.566
mtsB; iron/zinc/manganese/copper transport system ATP-binding protein	-0.126	0.191	0.509	0.566
mtsC; iron/zinc/manganese/copper transport system permease protein	-0.126	0.191	0.509	0.566
mtsT; energy-coupling factor transport system substrate-specific component	-0.126	0.191	0.509	0.566
murA; UDP-N-acetylglucosamine 1-carboxyvinyltransferase [EC:2.5.1.7]	-0.126	0.191	0.509	0.566
murB; UDP-N-acetylmuramate dehydrogenase [EC:1.3.1.98]	-0.126	0.191	0.509	0.566
murC; UDP-N-acetylmuramate–alanine ligase [EC:6.3.2.8]	-0.126	0.191	0.509	0.566
murD; UDP-N-acetylmuramoylalanine–D-glutamate ligase [EC:6.3.2.9]	-0.126	0.191	0.509	0.566
murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate–2,6-diaminopimelate ligase [EC:6.3.2.13]	-0.126	0.191	0.509	0.566
murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]	-0.126	0.191	0.509	0.566
murF; UDP-N-acetylmuramoyl-tripeptide–D-alanyl-D-alanine ligase [EC:6.3.2.10]	-0.126	0.191	0.509	0.566
murG; UDP-N-acetylglucosamine–N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC:2.4.1.227]	-0.126	0.191	0.509	0.566
murI; glutamate racemase [EC:5.1.1.3]	-0.126	0.191	0.509	0.566
murM; serine/alanine adding enzyme [EC:2.3.2.10]	-0.126	0.191	0.509	0.566
murN; alanine adding enzyme [EC:2.3.2.-]	-0.126	0.191	0.509	0.566
mutL; DNA mismatch repair protein MutL	-0.126	0.191	0.509	0.566
mutM, fpg; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]	-0.126	0.191	0.509	0.566
mutS; DNA mismatch repair protein MutS	-0.126	0.191	0.509	0.566
mutS2; DNA mismatch repair protein MutS2	-0.126	0.191	0.509	0.566
mutT, NUDT15, MTH2; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]	-0.128	0.194	0.510	0.566
mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]	-0.126	0.191	0.509	0.566
mvaA; hydroxymethylglutaryl-CoA reductase [EC:1.1.1.88]	-0.126	0.191	0.509	0.566
MVD, mvaD; diphosphomevalonate decarboxylase [EC:4.1.1.33]	-0.126	0.191	0.509	0.566
nadD; nicotinate-nucleotide adenylyltransferase [EC:2.7.7.18]	-0.126	0.191	0.509	0.566
nadE; NAD+ synthase [EC:6.3.1.5]	-0.126	0.191	0.509	0.566
nagA, AMDHD2; N-acetylglucosamine-6-phosphate deacetylase [EC:3.5.1.25]	-0.126	0.191	0.509	0.566
nagB, GNPDA; glucosamine-6-phosphate deaminase [EC:3.5.99.6]	-0.126	0.191	0.509	0.566
nanE; N-acylglucosamine-6-phosphate 2-epimerase [EC:5.1.3.9]	-0.126	0.191	0.509	0.566
NARS, asnS; asparaginyl-tRNA synthetase [EC:6.1.1.22]	-0.126	0.191	0.509	0.566
ndk, NME; nucleoside-diphosphate kinase [EC:2.7.4.6]	-0.121	0.201	0.548	0.566
NEU1; sialidase-1 [EC:3.2.1.18]	-0.121	0.201	0.548	0.566
niaX; niacin transporter	-0.126	0.191	0.509	0.566
npdA; NAD-dependent deacetylase [EC:3.5.1.-]	-0.126	0.191	0.509	0.566
NQO1; NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2]	-0.133	0.217	0.540	0.566
nrdG; anaerobic ribonucleoside-triphosphate reductase activating protein [EC:1.97.1.4]	-0.126	0.191	0.509	0.566
nrdH; glutaredoxin-like protein NrdH	-0.126	0.191	0.509	0.566
nrdI; protein involved in ribonucleotide reduction	-0.128	0.194	0.510	0.566
nrdR; transcriptional repressor NrdR	-0.126	0.191	0.509	0.566
nrnA; bifunctional oligoribonuclease and PAP phosphatase NrnA [EC:3.1.3.7 3.1.13.3]	-0.126	0.191	0.509	0.566
nspC; carboxynorspermidine decarboxylase [EC:4.1.1.96]	-0.121	0.201	0.548	0.566
NTH; endonuclease III [EC:4.2.99.18]	-0.126	0.191	0.509	0.566
nudB, ntpA; dihydroneopterin triphosphate diphosphatase [EC:3.6.1.67]	-0.133	0.217	0.540	0.566
nudF; ADP-ribose pyrophosphatase [EC:3.6.1.13]	-0.128	0.194	0.510	0.566
nusA; N utilization substance protein A	-0.126	0.191	0.509	0.566
nusB; N utilization substance protein B	-0.126	0.191	0.509	0.566
nusG; transcriptional antiterminator NusG	-0.126	0.191	0.509	0.566
obgE, cgtA; GTPase [EC:3.6.5.-]	-0.126	0.191	0.509	0.566
ogt, MGMT; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]	-0.126	0.191	0.509	0.566
oppA, mppA; oligopeptide transport system substrate-binding protein	-0.123	0.193	0.526	0.566
oppB; oligopeptide transport system permease protein	-0.126	0.191	0.509	0.566
oppC; oligopeptide transport system permease protein	-0.126	0.191	0.509	0.566
oppD; oligopeptide transport system ATP-binding protein	-0.126	0.191	0.509	0.566
oppF; oligopeptide transport system ATP-binding protein	-0.126	0.191	0.509	0.566
opuA; osmoprotectant transport system ATP-binding protein	-0.126	0.191	0.509	0.566
opuBD; osmoprotectant transport system permease protein	-0.126	0.191	0.509	0.566
OTC, argF, argI; ornithine carbamoyltransferase [EC:2.1.3.3]	-0.133	0.217	0.540	0.566
paaI; acyl-CoA thioesterase [EC:3.1.2.-]	-0.126	0.191	0.509	0.566
pabBC; para-aminobenzoate synthetase / 4-amino-4-deoxychorismate lyase [EC:2.6.1.85 4.1.3.38]	-0.126	0.191	0.509	0.566
padR; PadR family transcriptional regulator, regulatory protein PadR	-0.124	0.191	0.517	0.566
panE, apbA; 2-dehydropantoate 2-reductase [EC:1.1.1.169]	-0.335	1.544	0.829	0.829
parA, soj; chromosome partitioning protein	-0.335	1.544	0.829	0.829
parB, spo0J; chromosome partitioning protein, ParB family	-0.126	0.191	0.509	0.566
parC; topoisomerase IV subunit A [EC:5.99.1.-]	-0.126	0.191	0.509	0.566
parE; topoisomerase IV subunit B [EC:5.99.1.-]	-0.126	0.191	0.509	0.566
PARS, proS; prolyl-tRNA synthetase [EC:6.1.1.15]	-0.126	0.191	0.509	0.566
pat; phosphinothricin acetyltransferase [EC:2.3.1.183]	-0.133	0.217	0.540	0.566
patA, rscA, lmrC, satA; ATP-binding cassette, subfamily B, multidrug efflux pump	-0.126	0.191	0.509	0.566
patA; aminotransferase [EC:2.6.1.-]	-0.126	0.191	0.509	0.566
patB, malY; cystathione beta-lyase [EC:4.4.1.8]	-0.126	0.191	0.509	0.566
patB, rscB, lmrC, satB; ATP-binding cassette, subfamily B, multidrug efflux pump	-0.126	0.191	0.509	0.566
pbp1b; penicillin-binding protein 1B	-0.126	0.191	0.509	0.566
pbp2A; penicillin-binding protein 2A [EC:2.4.1.129 3.4.16.4]	-0.126	0.191	0.509	0.566
pbp2B, penA; penicillin-binding protein 2B	-0.126	0.191	0.509	0.566
pbp2X; penicillin-binding protein 2X	-0.126	0.191	0.509	0.566
pbuG; putative MFS transporter, AGZA family, xanthine/uracil permease	-0.126	0.191	0.509	0.566
pbuX; xanthine permease	-0.121	0.201	0.547	0.566
pcaC; 4-carboxymuconolactone decarboxylase [EC:4.1.1.44]	-0.335	1.544	0.829	0.829
pcp; pyroglutamyl-peptidase [EC:3.4.19.3]	-0.121	0.201	0.548	0.566
PDF, def; peptide deformylase [EC:3.5.1.88]	-0.126	0.191	0.509	0.566
PDHA, pdhA; pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1]	-0.126	0.191	0.509	0.566
PDHB, pdhB; pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1]	-0.126	0.191	0.509	0.566
pdp; pyrimidine-nucleoside phosphorylase [EC:2.4.2.2]	-0.126	0.191	0.509	0.566
pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]	-0.129	0.198	0.514	0.566
pdxK, pdxY; pyridoxine kinase [EC:2.7.1.35]	-0.128	0.194	0.510	0.566
pdxS, pdx1; pyridoxal 5’-phosphate synthase pdxS subunit [EC:4.3.3.6]	-0.121	0.201	0.548	0.566
pdxT, pdx2; 5’-phosphate synthase pdxT subunit [EC:4.3.3.6]	-0.121	0.201	0.548	0.566
pepA; glutamyl aminopeptidase [EC:3.4.11.7]	-0.126	0.191	0.509	0.566
pepDA, pepDB; dipeptidase [EC:3.4.-.-]	-0.133	0.217	0.540	0.566
pepE; dipeptidase E [EC:3.4.13.21]	-0.133	0.217	0.540	0.566
pepF, pepB; oligoendopeptidase F [EC:3.4.24.-]	-0.126	0.191	0.509	0.566
pepN; aminopeptidase N [EC:3.4.11.2]	-0.126	0.191	0.509	0.566
pepO; putative endopeptidase [EC:3.4.24.-]	-0.126	0.191	0.509	0.566
pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]	-0.126	0.191	0.509	0.566
pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]	-0.126	0.191	0.509	0.566
pepT; tripeptide aminopeptidase [EC:3.4.11.4]	-0.126	0.191	0.509	0.566
pepX; X-Pro dipeptidyl-peptidase [EC:3.4.14.11]	-0.128	0.194	0.510	0.566
perR; Fur family transcriptional regulator, peroxide stress response regulator	-0.133	0.217	0.540	0.566
pezA; HTH-type transcriptional regulator / antitoxin PezA	-0.121	0.201	0.547	0.566
pezT; UDP-N-acetylglucosamine kinase [EC:2.7.1.176]	-0.121	0.201	0.547	0.566
pfkA, PFK; 6-phosphofructokinase 1 [EC:2.7.1.11]	-0.126	0.191	0.509	0.566
pflA, pflC, pflE; pyruvate formate lyase activating enzyme [EC:1.97.1.4]	-0.128	0.194	0.510	0.566
PGAM, gpmA; 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11]	-0.126	0.191	0.509	0.566
PGD, gnd, gntZ; 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343]	-0.126	0.191	0.509	0.566
PGK, pgk; phosphoglycerate kinase [EC:2.7.2.3]	-0.126	0.191	0.509	0.566
pgl; 6-phosphogluconolactonase [EC:3.1.1.31]	-0.126	0.191	0.509	0.566
pgm; phosphoglucomutase [EC:5.4.2.2]	-0.126	0.191	0.509	0.566
pgsA, PGS1; CDP-diacylglycerol—glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5]	-0.126	0.191	0.509	0.566
pheA2; prephenate dehydratase [EC:4.2.1.51]	-0.126	0.191	0.509	0.566
phnA; protein PhnA	-0.126	0.191	0.509	0.566
phnB; PhnB protein	-0.133	0.217	0.540	0.566
phoH, phoL; phosphate starvation-inducible protein PhoH and related proteins	-0.126	0.191	0.509	0.566
phoU; phosphate transport system protein	-0.126	0.191	0.509	0.566
PK, pyk; pyruvate kinase [EC:2.7.1.40]	-0.126	0.191	0.509	0.566
plsC; 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC:2.3.1.51]	-0.126	0.191	0.509	0.566
plsX; glycerol-3-phosphate acyltransferase PlsX [EC:2.3.1.15]	-0.126	0.191	0.509	0.566
plsY; glycerol-3-phosphate acyltransferase PlsY [EC:2.3.1.15]	-0.126	0.191	0.509	0.566
pncB, NAPRT1; nicotinate phosphoribosyltransferase [EC:6.3.4.21]	-0.126	0.191	0.509	0.566
pncC; nicotinamide-nucleotide amidase [EC:3.5.1.42]	-0.126	0.191	0.509	0.566
pnp, PNPT1; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]	-0.126	0.191	0.509	0.566
pnuC; nicotinamide mononucleotide transporter	-0.126	0.191	0.509	0.566
polA; DNA polymerase I [EC:2.7.7.7]	-0.126	0.191	0.509	0.566
polC; DNA polymerase III subunit alpha, Gram-positive type [EC:2.7.7.7]	-0.126	0.191	0.509	0.566
potA; spermidine/putrescine transport system ATP-binding protein [EC:3.6.3.31]	-0.126	0.191	0.509	0.566
potB; spermidine/putrescine transport system permease protein	-0.126	0.191	0.509	0.566
potC; spermidine/putrescine transport system permease protein	-0.126	0.191	0.509	0.566
potD; spermidine/putrescine transport system substrate-binding protein	-0.126	0.191	0.509	0.566
ppaC; manganese-dependent inorganic pyrophosphatase [EC:3.6.1.1]	-0.126	0.191	0.509	0.566
ppc; phosphoenolpyruvate carboxylase [EC:4.1.1.31]	-0.126	0.191	0.509	0.566
PPCDC, coaC; phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36]	-0.126	0.191	0.509	0.566
PPCS, COAB; phosphopantothenate—cysteine ligase (ATP) [EC:6.3.2.51]	-0.126	0.191	0.509	0.566
ppdK; pyruvate, orthophosphate dikinase [EC:2.7.9.1]	-0.133	0.217	0.540	0.566
pphA; serine/threonine protein phosphatase 1 [EC:3.1.3.16]	-0.126	0.191	0.509	0.566
PPIA; peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]	-0.126	0.191	0.509	0.566
PPIB, ppiB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]	-0.126	0.191	0.509	0.566
ppnK, NADK; NAD+ kinase [EC:2.7.1.23]	-0.126	0.191	0.509	0.566
pps, ppsA; pyruvate, water dikinase [EC:2.7.9.2]	-0.133	0.217	0.540	0.566
ppsR; [pyruvate, water dikinase]-phosphate phosphotransferase / [pyruvate, water dikinase] kinase [EC:2.7.4.28 2.7.11.33]	-0.133	0.217	0.541	0.566
praC, xylH; 4-oxalocrotonate tautomerase [EC:5.3.2.6]	-0.126	0.191	0.509	0.566
prdX, proX; Ala-tRNA(Pro) deacylase [EC:3.1.1.-]	-0.133	0.217	0.540	0.566
prfA, MTRF1, MRF1; peptide chain release factor 1	-0.126	0.191	0.509	0.566
prfB; peptide chain release factor 2	-0.126	0.191	0.509	0.566
prfC; peptide chain release factor 3	-0.126	0.191	0.509	0.566
priA; primosomal protein N’ (replication factor Y) (superfamily II helicase) [EC:3.6.4.-]	-0.126	0.191	0.509	0.566
prmA; ribosomal protein L11 methyltransferase [EC:2.1.1.-]	-0.126	0.191	0.509	0.566
proA; glutamate-5-semialdehyde dehydrogenase [EC:1.2.1.41]	-0.126	0.191	0.509	0.566
proB; glutamate 5-kinase [EC:2.7.2.11]	-0.126	0.191	0.509	0.566
proC; pyrroline-5-carboxylate reductase [EC:1.5.1.2]	-0.126	0.191	0.509	0.566
proV; glycine betaine/proline transport system ATP-binding protein [EC:3.6.3.32]	-0.335	1.544	0.829	0.829
proX; glycine betaine/proline transport system substrate-binding protein	-0.335	1.544	0.829	0.829
PRPS, prsA; ribose-phosphate pyrophosphokinase [EC:2.7.6.1]	-0.126	0.191	0.509	0.566
prsA; foldase protein PrsA [EC:5.2.1.8]	-0.126	0.191	0.509	0.566
psd, PISD; phosphatidylserine decarboxylase [EC:4.1.1.65]	-0.133	0.217	0.540	0.566
pstA; phosphate transport system permease protein	-0.126	0.191	0.509	0.566
pstB; phosphate transport system ATP-binding protein [EC:3.6.3.27]	-0.125	0.191	0.513	0.566
pstC; phosphate transport system permease protein	-0.126	0.191	0.509	0.566
pstS; phosphate transport system substrate-binding protein	-0.126	0.191	0.509	0.566
PTH1, pth, spoVC; peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29]	-0.126	0.191	0.509	0.566
PTS-Aga-EIIA, agaF; PTS system, N-acetylgalactosamine-specific IIA component [EC:2.7.1.-]	-0.126	0.191	0.509	0.566
PTS-Bgl-EIIC, bglF, bglP; PTS system, beta-glucoside-specific IIC component	-0.335	1.544	0.829	0.829
PTS-Cel-EIIA, celC, chbA; PTS system, cellobiose-specific IIA component [EC:2.7.1.196 2.7.1.205]	-0.133	0.217	0.541	0.566
PTS-Cel-EIIB, celA, chbB; PTS system, cellobiose-specific IIB component [EC:2.7.1.196 2.7.1.205]	-0.133	0.217	0.541	0.566
PTS-Cel-EIIC, celB, chbC; PTS system, cellobiose-specific IIC component	-0.133	0.217	0.541	0.566
PTS-EI.PTSI, ptsI; phosphotransferase system, enzyme I, PtsI [EC:2.7.3.9]	-0.126	0.191	0.509	0.566
PTS-Fru-EIIC, fruA; PTS system, fructose-specific IIC component	-0.126	0.191	0.509	0.566
PTS-Fru1-EIID, levG; PTS system, fructose-specific IID component	-0.126	0.191	0.509	0.566
PTS-Gat-EIIA, gatA, sgcA; PTS system, galactitol-specific IIA component [EC:2.7.1.200]	-0.121	0.201	0.547	0.566
PTS-Gat-EIIB, gatB, sgcB; PTS system, galactitol-specific IIB component [EC:2.7.1.200]	-0.121	0.201	0.547	0.566
PTS-Gat-EIIC, gatC, sgcC; PTS system, galactitol-specific IIC component	-0.121	0.201	0.547	0.566
PTS-Glc-EIIC, ptsG; PTS system, glucose-specific IIC component	-0.126	0.191	0.509	0.566
PTS-Gut-EIIA, srlB; PTS system, glucitol/sorbitol-specific IIA component [EC:2.7.1.198]	-0.335	1.544	0.829	0.829
PTS-Gut-EIIC, srlA; PTS system, glucitol/sorbitol-specific IIC component	-0.335	1.544	0.829	0.829
PTS-HPR; phosphocarrier protein	-0.126	0.191	0.509	0.566
PTS-Lac-EIIA, lacF; PTS system, lactose-specific IIA component [EC:2.7.1.207]	-0.126	0.191	0.509	0.566
PTS-Lac-EIIC, lacE; PTS system, lactose-specific IIC component	-0.126	0.191	0.509	0.566
PTS-Man-EIIA, manX; PTS system, mannose-specific IIA component [EC:2.7.1.191]	-0.126	0.191	0.509	0.566
PTS-Man-EIIB, manX; PTS system, mannose-specific IIB component [EC:2.7.1.191]	-0.126	0.191	0.509	0.566
PTS-Man-EIIC, manY; PTS system, mannose-specific IIC component	-0.126	0.191	0.509	0.566
PTS-Man-EIID, manZ; PTS system, mannose-specific IID component	-0.126	0.191	0.509	0.566
PTS-Scr-EIIC, scrA, sacP, sacX, ptsS; PTS system, sucrose-specific IIC component	-0.126	0.191	0.509	0.566
PTS-Tre-EIIC, treB; PTS system, trehalose-specific IIC component	-0.133	0.217	0.540	0.566
PTS-Ula-EIIA, ulaC, sgaA; PTS system, ascorbate-specific IIA component [EC:2.7.1.194]	-0.133	0.217	0.541	0.566
PTS-Ula-EIIB, ulaB, sgaB; PTS system, ascorbate-specific IIB component [EC:2.7.1.194]	-0.126	0.191	0.510	0.566
PTS-Ula-EIIC, ulaA, sgaT; PTS system, ascorbate-specific IIC component	-0.126	0.191	0.510	0.566
pulA; pullulanase [EC:3.2.1.41]	-0.129	0.198	0.514	0.566
punA, PNP; purine-nucleoside phosphorylase [EC:2.4.2.1]	-0.126	0.191	0.509	0.566
purA, ADSS; adenylosuccinate synthase [EC:6.3.4.4]	-0.126	0.191	0.509	0.566
purB, ADSL; adenylosuccinate lyase [EC:4.3.2.2]	-0.126	0.191	0.509	0.566
purC; phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:6.3.2.6]	-0.126	0.191	0.509	0.566
purD; phosphoribosylamine—glycine ligase [EC:6.3.4.13]	-0.126	0.191	0.509	0.566
purE; 5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]	-0.126	0.191	0.509	0.566
purF, PPAT; amidophosphoribosyltransferase [EC:2.4.2.14]	-0.126	0.191	0.509	0.566
purH; phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]	-0.126	0.191	0.509	0.566
purK; 5-(carboxyamino)imidazole ribonucleotide synthase [EC:6.3.4.18]	-0.126	0.191	0.509	0.566
purL, PFAS; phosphoribosylformylglycinamidine synthase [EC:6.3.5.3]	-0.126	0.191	0.509	0.566
purM; phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.3.1]	-0.126	0.191	0.509	0.566
purN; phosphoribosylglycinamide formyltransferase 1 [EC:2.1.2.2]	-0.126	0.191	0.509	0.566
purR; purine operon repressor	-0.126	0.191	0.509	0.566
PYG, glgP; glycogen phosphorylase [EC:2.4.1.1]	-0.128	0.194	0.510	0.566
pyrB, PYR2; aspartate carbamoyltransferase catalytic subunit [EC:2.1.3.2]	-0.126	0.191	0.509	0.566
pyrD; dihydroorotate dehydrogenase (fumarate) [EC:1.3.98.1]	-0.126	0.191	0.509	0.566
pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:1.3.1.14]	-0.126	0.191	0.509	0.566
pyrDII; dihydroorotate dehydrogenase electron transfer subunit	-0.126	0.191	0.509	0.566
pyrE; orotate phosphoribosyltransferase [EC:2.4.2.10]	-0.126	0.191	0.509	0.566
pyrF; orotidine-5’-phosphate decarboxylase [EC:4.1.1.23]	-0.126	0.191	0.509	0.566
pyrG, CTPS; CTP synthase [EC:6.3.4.2]	-0.126	0.191	0.509	0.566
pyrH; uridylate kinase [EC:2.7.4.22]	-0.126	0.191	0.509	0.566
pyrP, uraA; uracil permease	-0.126	0.191	0.509	0.566
pyrR; pyrimidine operon attenuation protein / uracil phosphoribosyltransferase [EC:2.4.2.9]	-0.126	0.191	0.509	0.566
qrtT; energy-coupling factor transport system substrate-specific component	-0.335	1.544	0.829	0.829
queA; S-adenosylmethionine:tRNA ribosyltransferase-isomerase [EC:2.4.99.17]	-0.126	0.191	0.509	0.566
queC; 7-cyano-7-deazaguanine synthase [EC:6.3.4.20]	-0.121	0.201	0.548	0.566
queD, ptpS, PTS; 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50]	-0.121	0.201	0.548	0.566
queE; 7-carboxy-7-deazaguanine synthase [EC:4.3.99.3]	-0.121	0.201	0.548	0.566
queF; 7-cyano-7-deazaguanine reductase [EC:1.7.1.13]	-0.121	0.201	0.548	0.566
queG; epoxyqueuosine reductase [EC:1.17.99.6]	-0.133	0.217	0.541	0.566
queH; epoxyqueuosine reductase [EC:1.17.99.6]	-0.121	0.201	0.547	0.566
racD; aspartate racemase [EC:5.1.1.13]	-0.335	1.544	0.829	0.829
radA, sms; DNA repair protein RadA/Sms	-0.126	0.191	0.509	0.566
radC; DNA repair protein RadC	-0.126	0.191	0.509	0.566
rapZ; RNase adapter protein RapZ	-0.126	0.191	0.509	0.566
RARS, argS; arginyl-tRNA synthetase [EC:6.1.1.19]	-0.126	0.191	0.509	0.566
rbfA; ribosome-binding factor A	-0.126	0.191	0.509	0.566
rbgA; ribosome biogenesis GTPase A	-0.126	0.191	0.509	0.566
rbsB; ribose transport system substrate-binding protein	-0.126	0.191	0.509	0.566
rdgB; XTP/dITP diphosphohydrolase [EC:3.6.1.66]	-0.126	0.191	0.509	0.566
recA; recombination protein RecA	-0.126	0.191	0.509	0.566
recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]	-0.126	0.191	0.509	0.566
recF; DNA replication and repair protein RecF	-0.126	0.191	0.509	0.566
recG; ATP-dependent DNA helicase RecG [EC:3.6.4.12]	-0.126	0.191	0.509	0.566
recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]	-0.126	0.191	0.509	0.566
recN; DNA repair protein RecN (Recombination protein N)	-0.126	0.191	0.509	0.566
recO; DNA repair protein RecO (recombination protein O)	-0.126	0.191	0.509	0.566
recR; recombination protein RecR	-0.126	0.191	0.509	0.566
recU; recombination protein U	-0.126	0.191	0.509	0.566
recX; regulatory protein	-0.126	0.191	0.509	0.566
relA; GTP pyrophosphokinase [EC:2.7.6.5]	-0.126	0.191	0.509	0.566
relE, stbE; mRNA interferase RelE/StbE	-0.121	0.201	0.547	0.566
rex; redox-sensing transcriptional repressor	-0.126	0.191	0.509	0.566
rfbC, rmlC; dTDP-4-dehydrorhamnose 3,5-epimerase [EC:5.1.3.13]	-0.133	0.217	0.540	0.566
rfbD, rmlD; dTDP-4-dehydrorhamnose reductase [EC:1.1.1.133]	-0.133	0.217	0.540	0.566
rgpA; rhamnosyltransferase [EC:2.4.1.-]	-0.133	0.217	0.539	0.566
rgpB; rhamnosyltransferase [EC:2.4.1.-]	-0.133	0.217	0.540	0.566
rgpE; glucosyltransferase [EC:2.4.1.-]	-0.335	1.544	0.829	0.829
rgpF; rhamnosyltransferase [EC:2.4.1.-]	-0.133	0.217	0.540	0.566
ribF; riboflavin kinase / FMN adenylyltransferase [EC:2.7.1.26 2.7.7.2]	-0.126	0.191	0.509	0.566
ridA, tdcF, RIDA; 2-iminobutanoate/2-iminopropanoate deaminase [EC:3.5.99.10]	-0.126	0.191	0.509	0.566
rimI; [ribosomal protein S18]-alanine N-acetyltransferase [EC:2.3.1.266]	-0.128	0.194	0.510	0.566
rimJ; [ribosomal protein S5]-alanine N-acetyltransferase [EC:2.3.1.267]	-0.128	0.194	0.510	0.566
rimM; 16S rRNA processing protein RimM	-0.126	0.191	0.509	0.566
rimP; ribosome maturation factor RimP	-0.126	0.191	0.509	0.566
rlmA1; 23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]	-0.126	0.191	0.509	0.566
rlmB; 23S rRNA (guanosine2251-2’-O)-methyltransferase [EC:2.1.1.185]	-0.126	0.191	0.509	0.566
rlmH; 23S rRNA (pseudouridine1915-N3)-methyltransferase [EC:2.1.1.177]	-0.126	0.191	0.509	0.566
rlmI; 23S rRNA (cytosine1962-C5)-methyltransferase [EC:2.1.1.191]	-0.126	0.191	0.509	0.566
rlmN; 23S rRNA (adenine2503-C2)-methyltransferase [EC:2.1.1.192]	-0.126	0.191	0.509	0.566
rluA; tRNA pseudouridine32 synthase / 23S rRNA pseudouridine746 synthase [EC:5.4.99.28 5.4.99.29]	-0.133	0.217	0.540	0.566
rluB; 23S rRNA pseudouridine2605 synthase [EC:5.4.99.22]	-0.126	0.191	0.509	0.566
rluD; 23S rRNA pseudouridine1911/1915/1917 synthase [EC:5.4.99.23]	-0.126	0.191	0.509	0.566
rmuC; DNA recombination protein RmuC	-0.126	0.191	0.509	0.566
rnc, DROSHA, RNT1; ribonuclease III [EC:3.1.26.3]	-0.126	0.191	0.509	0.566
rnhB; ribonuclease HII [EC:3.1.26.4]	-0.124	0.191	0.517	0.566
rnhC; ribonuclease HIII [EC:3.1.26.4]	-0.126	0.191	0.509	0.566
rnj; ribonuclease J [EC:3.1.-.-]	-0.126	0.191	0.509	0.566
rnmV; ribonuclease M5 [EC:3.1.26.8]	-0.126	0.191	0.509	0.566
rnpA; ribonuclease P protein component [EC:3.1.26.5]	-0.126	0.191	0.509	0.566
rnr, vacB; ribonuclease R [EC:3.1.-.-]	-0.126	0.191	0.509	0.566
rny; ribonucrease Y [EC:3.1.-.-]	-0.126	0.191	0.509	0.566
rnz; ribonuclease Z [EC:3.1.26.11]	-0.126	0.191	0.509	0.566
rodA, mrdB; rod shape determining protein RodA	-0.126	0.191	0.509	0.566
RP-L1, MRPL1, rplA; large subunit ribosomal protein L1	-0.126	0.191	0.509	0.566
RP-L10, MRPL10, rplJ; large subunit ribosomal protein L10	-0.126	0.191	0.509	0.566
RP-L11, MRPL11, rplK; large subunit ribosomal protein L11	-0.126	0.191	0.509	0.566
RP-L13, MRPL13, rplM; large subunit ribosomal protein L13	-0.126	0.191	0.509	0.566
RP-L14, MRPL14, rplN; large subunit ribosomal protein L14	-0.126	0.191	0.509	0.566
RP-L15, MRPL15, rplO; large subunit ribosomal protein L15	-0.126	0.191	0.509	0.566
RP-L16, MRPL16, rplP; large subunit ribosomal protein L16	-0.126	0.191	0.509	0.566
RP-L17, MRPL17, rplQ; large subunit ribosomal protein L17	-0.126	0.191	0.509	0.566
RP-L18, MRPL18, rplR; large subunit ribosomal protein L18	-0.126	0.191	0.509	0.566
RP-L19, MRPL19, rplS; large subunit ribosomal protein L19	-0.126	0.191	0.509	0.566
RP-L2, MRPL2, rplB; large subunit ribosomal protein L2	-0.126	0.191	0.509	0.566
RP-L20, MRPL20, rplT; large subunit ribosomal protein L20	-0.126	0.191	0.509	0.566
RP-L21, MRPL21, rplU; large subunit ribosomal protein L21	-0.126	0.191	0.509	0.566
RP-L22, MRPL22, rplV; large subunit ribosomal protein L22	-0.126	0.191	0.509	0.566
RP-L23, MRPL23, rplW; large subunit ribosomal protein L23	-0.126	0.191	0.509	0.566
RP-L24, MRPL24, rplX; large subunit ribosomal protein L24	-0.126	0.191	0.509	0.566
RP-L27, MRPL27, rpmA; large subunit ribosomal protein L27	-0.126	0.191	0.509	0.566
RP-L28, MRPL28, rpmB; large subunit ribosomal protein L28	-0.126	0.191	0.509	0.566
RP-L29, rpmC; large subunit ribosomal protein L29	-0.126	0.191	0.509	0.566
RP-L3, MRPL3, rplC; large subunit ribosomal protein L3	-0.126	0.191	0.509	0.566
RP-L30, MRPL30, rpmD; large subunit ribosomal protein L30	-0.126	0.191	0.509	0.566
RP-L31, rpmE; large subunit ribosomal protein L31	-0.126	0.191	0.509	0.566
RP-L32, MRPL32, rpmF; large subunit ribosomal protein L32	-0.126	0.191	0.509	0.566
RP-L33, MRPL33, rpmG; large subunit ribosomal protein L33	-0.128	0.194	0.510	0.566
RP-L34, MRPL34, rpmH; large subunit ribosomal protein L34	-0.126	0.191	0.509	0.566
RP-L35, MRPL35, rpmI; large subunit ribosomal protein L35	-0.126	0.191	0.509	0.566
RP-L36, MRPL36, rpmJ; large subunit ribosomal protein L36	-0.133	0.217	0.540	0.566
RP-L4, MRPL4, rplD; large subunit ribosomal protein L4	-0.126	0.191	0.509	0.566
RP-L5, MRPL5, rplE; large subunit ribosomal protein L5	-0.126	0.191	0.509	0.566
RP-L6, MRPL6, rplF; large subunit ribosomal protein L6	-0.126	0.191	0.509	0.566
RP-L7, MRPL12, rplL; large subunit ribosomal protein L7/L12	-0.126	0.191	0.509	0.566
RP-L9, MRPL9, rplI; large subunit ribosomal protein L9	-0.126	0.191	0.509	0.566
RP-S1, rpsA; small subunit ribosomal protein S1	-0.126	0.191	0.509	0.566
RP-S10, MRPS10, rpsJ; small subunit ribosomal protein S10	-0.126	0.191	0.509	0.566
RP-S11, MRPS11, rpsK; small subunit ribosomal protein S11	-0.126	0.191	0.509	0.566
RP-S12, MRPS12, rpsL; small subunit ribosomal protein S12	-0.126	0.191	0.509	0.566
RP-S13, rpsM; small subunit ribosomal protein S13	-0.126	0.191	0.509	0.566
RP-S14, MRPS14, rpsN; small subunit ribosomal protein S14	-0.126	0.191	0.509	0.566
RP-S15, MRPS15, rpsO; small subunit ribosomal protein S15	-0.126	0.191	0.509	0.566
RP-S16, MRPS16, rpsP; small subunit ribosomal protein S16	-0.126	0.191	0.509	0.566
RP-S17, MRPS17, rpsQ; small subunit ribosomal protein S17	-0.126	0.191	0.509	0.566
RP-S18, MRPS18, rpsR; small subunit ribosomal protein S18	-0.126	0.191	0.509	0.566
RP-S19, rpsS; small subunit ribosomal protein S19	-0.126	0.191	0.509	0.566
RP-S2, MRPS2, rpsB; small subunit ribosomal protein S2	-0.126	0.191	0.509	0.566
RP-S20, rpsT; small subunit ribosomal protein S20	-0.126	0.191	0.509	0.566
RP-S21, MRPS21, rpsU; small subunit ribosomal protein S21	-0.126	0.191	0.509	0.566
RP-S3, rpsC; small subunit ribosomal protein S3	-0.126	0.191	0.509	0.566
RP-S4, rpsD; small subunit ribosomal protein S4	-0.126	0.191	0.509	0.566
RP-S5, MRPS5, rpsE; small subunit ribosomal protein S5	-0.126	0.191	0.509	0.566
RP-S6, MRPS6, rpsF; small subunit ribosomal protein S6	-0.126	0.191	0.509	0.566
RP-S7, MRPS7, rpsG; small subunit ribosomal protein S7	-0.126	0.191	0.509	0.566
RP-S8, rpsH; small subunit ribosomal protein S8	-0.126	0.191	0.509	0.566
RP-S9, MRPS9, rpsI; small subunit ribosomal protein S9	-0.126	0.191	0.509	0.566
rpe, RPE; ribulose-phosphate 3-epimerase [EC:5.1.3.1]	-0.126	0.191	0.509	0.566
rpiA; ribose 5-phosphate isomerase A [EC:5.3.1.6]	-0.126	0.191	0.509	0.566
rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]	-0.126	0.191	0.509	0.566
rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]	-0.126	0.191	0.509	0.566
rpoC; DNA-directed RNA polymerase subunit beta’ [EC:2.7.7.6]	-0.126	0.191	0.509	0.566
rpoD; RNA polymerase primary sigma factor	-0.126	0.191	0.509	0.566
rpoE; DNA-directed RNA polymerase subunit delta	-0.126	0.191	0.509	0.566
rpoE; RNA polymerase sigma-70 factor, ECF subfamily	-0.133	0.217	0.541	0.566
rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]	-0.126	0.191	0.509	0.566
rseP; regulator of sigma E protease [EC:3.4.24.-]	-0.126	0.191	0.509	0.566
rsgA, engC; ribosome biogenesis GTPase / thiamine phosphate phosphatase [EC:3.6.1.- 3.1.3.100]	-0.126	0.191	0.509	0.566
rsmB, sun; 16S rRNA (cytosine967-C5)-methyltransferase [EC:2.1.1.176]	-0.126	0.191	0.509	0.566
rsmC; 16S rRNA (guanine1207-N2)-methyltransferase [EC:2.1.1.172]	-0.126	0.191	0.509	0.566
rsmD; 16S rRNA (guanine966-N2)-methyltransferase [EC:2.1.1.171]	-0.126	0.191	0.509	0.566
rsmE; 16S rRNA (uracil1498-N3)-methyltransferase [EC:2.1.1.193]	-0.126	0.191	0.509	0.566
rsmI; 16S rRNA (cytidine1402-2’-O)-methyltransferase [EC:2.1.1.198]	-0.126	0.191	0.509	0.566
rstA1; phage replication initiation protein	-0.335	1.544	0.829	0.829
rsuA; 16S rRNA pseudouridine516 synthase [EC:5.4.99.19]	-0.126	0.191	0.509	0.566
rtpR; ribonucleoside-triphosphate reductase (thioredoxin) [EC:1.17.4.2]	-0.126	0.191	0.509	0.566
rumA; 23S rRNA (uracil1939-C5)-methyltransferase [EC:2.1.1.190]	-0.126	0.191	0.509	0.566
ruvA; holliday junction DNA helicase RuvA [EC:3.6.4.12]	-0.126	0.191	0.509	0.566
ruvB; holliday junction DNA helicase RuvB [EC:3.6.4.12]	-0.126	0.191	0.509	0.566
ruvX; putative holliday junction resolvase [EC:3.1.-.-]	-0.126	0.191	0.509	0.566
saeR; two-component system, OmpR family, response regulator SaeR	-0.126	0.191	0.509	0.566
saeS; two-component system, OmpR family, sensor histidine kinase SaeS [EC:2.7.13.3]	-0.126	0.191	0.509	0.566
SARS, serS; seryl-tRNA synthetase [EC:6.1.1.11]	-0.126	0.191	0.509	0.566
sbcC, rad50; DNA repair protein SbcC/Rad50	-0.335	1.544	0.829	0.829
scpA; segregation and condensation protein A	-0.126	0.191	0.509	0.566
scpB; segregation and condensation protein B	-0.126	0.191	0.509	0.566
scrR; LacI family transcriptional regulator, sucrose operon repressor	-0.126	0.191	0.509	0.566
secA; preprotein translocase subunit SecA	-0.126	0.191	0.509	0.566
secE; preprotein translocase subunit SecE	-0.133	0.217	0.540	0.566
secG; preprotein translocase subunit SecG	-0.126	0.191	0.509	0.566
secY; preprotein translocase subunit SecY	-0.126	0.191	0.509	0.566
sepF; cell division inhibitor SepF	-0.126	0.191	0.509	0.566
serA, PHGDH; D-3-phosphoglycerate dehydrogenase / 2-oxoglutarate reductase [EC:1.1.1.95 1.1.1.399]	-0.133	0.217	0.541	0.566
serB, PSPH; phosphoserine phosphatase [EC:3.1.3.3]	-0.126	0.191	0.509	0.566
serC, PSAT1; phosphoserine aminotransferase [EC:2.6.1.52]	-0.133	0.217	0.541	0.566
slo; thiol-activated cytolysin	-0.121	0.201	0.548	0.566
smc; chromosome segregation protein	-0.126	0.191	0.509	0.566
smf; DNA processing protein	-0.126	0.191	0.509	0.566
smpB; SsrA-binding protein	-0.126	0.191	0.509	0.566
SOD2; superoxide dismutase, Fe-Mn family [EC:1.15.1.1]	-0.126	0.191	0.509	0.566
speE, SRM; spermidine synthase [EC:2.5.1.16]	-0.121	0.201	0.548	0.566
speG, SAT; diamine N-acetyltransferase [EC:2.3.1.57]	-0.121	0.201	0.547	0.566
spoU; RNA methyltransferase, TrmH family	-0.126	0.191	0.509	0.566
SPP; sucrose-6-phosphatase [EC:3.1.3.24]	-0.127	0.191	0.509	0.566
sprL; SprT-like protein	-0.133	0.217	0.540	0.566
spxA; regulatory protein spx	-0.126	0.191	0.510	0.566
srlD; sorbitol-6-phosphate 2-dehydrogenase [EC:1.1.1.140]	-0.335	1.544	0.829	0.829
SRP54, ffh; signal recognition particle subunit SRP54 [EC:3.6.5.4]	-0.126	0.191	0.509	0.566
srtA; sortase A [EC:3.4.22.70]	-0.128	0.194	0.510	0.566
srtB; sortase B [EC:3.4.22.70]	-0.133	0.217	0.540	0.566
ssb; single-strand DNA-binding protein	-0.126	0.191	0.509	0.566
sstT; serine/threonine transporter	-0.126	0.191	0.509	0.566
sufB; Fe-S cluster assembly protein SufB	-0.128	0.194	0.510	0.566
sufC; Fe-S cluster assembly ATP-binding protein	-0.126	0.191	0.509	0.566
sufD; Fe-S cluster assembly protein SufD	-0.126	0.191	0.509	0.566
sufS; cysteine desulfurase / selenocysteine lyase [EC:2.8.1.7 4.4.1.16]	-0.126	0.191	0.509	0.566
sulD; dihydroneopterin aldolase / 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [EC:4.1.2.25 2.7.6.3]	-0.126	0.191	0.509	0.566
tadA; tRNA(adenine34) deaminase [EC:3.5.4.33]	-0.126	0.191	0.509	0.566
tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]	-0.126	0.191	0.509	0.566
tagE; poly(glycerol-phosphate) alpha-glucosyltransferase [EC:2.4.1.52]	-0.133	0.217	0.540	0.566
tarJ; ribitol-5-phosphate 2-dehydrogenase (NADP+) [EC:1.1.1.405]	-0.121	0.201	0.548	0.566
TARS, thrS; threonyl-tRNA synthetase [EC:6.1.1.3]	-0.126	0.191	0.509	0.566
tatA; sec-independent protein translocase protein TatA	-0.133	0.217	0.540	0.566
tatC; sec-independent protein translocase protein TatC	-0.133	0.217	0.540	0.566
tatD; TatD DNase family protein [EC:3.1.21.-]	-0.126	0.191	0.509	0.566
TC.AAT; amino acid transporter, AAT family	-0.121	0.201	0.548	0.566
TC.AGCS; alanine or glycine:cation symporter, AGCS family	-0.126	0.191	0.510	0.566
TC.APA; basic amino acid/polyamine antiporter, APA family	-0.126	0.191	0.509	0.566
TC.CPA1; monovalent cation:H+ antiporter, CPA1 family	-0.121	0.201	0.548	0.566
TC.DAACS; dicarboxylate/amino acid:cation (Na+ or H+) symporter, DAACS family	-0.133	0.217	0.540	0.566
TC.LIVCS; branched-chain amino acid:cation transporter, LIVCS family	-0.126	0.191	0.509	0.566
TC.MATE, SLC47A, norM, mdtK, dinF; multidrug resistance protein, MATE family	-0.126	0.191	0.509	0.566
TC.NSS; neurotransmitter:Na+ symporter, NSS family	-0.121	0.201	0.548	0.566
TC.POT; proton-dependent oligopeptide transporter, POT family	-0.121	0.201	0.548	0.566
TC.SSS; solute:Na+ symporter, SSS family	-0.335	1.544	0.829	0.829
TC.ZIP, zupT, ZRT3, ZIP2; zinc transporter, ZIP family	-0.133	0.217	0.540	0.566
tcyK; L-cystine transport system substrate-binding protein	-0.126	0.191	0.510	0.566
tcyL; L-cystine transport system permease protein	-0.126	0.191	0.510	0.566
tcyM; L-cystine transport system permease protein	-0.124	0.191	0.517	0.566
tcyN; L-cystine transport system ATP-binding protein [EC:3.6.3.-]	-0.126	0.191	0.510	0.566
tdk, TK; thymidine kinase [EC:2.7.1.21]	-0.126	0.191	0.509	0.566
tehB; tellurite methyltransferase [EC:2.1.1.265]	-0.126	0.191	0.509	0.566
tenA; thiaminase (transcriptional activator TenA) [EC:3.5.99.2]	-0.121	0.201	0.548	0.566
tex; protein Tex	-0.126	0.191	0.509	0.566
tgt, QTRT1; queuine tRNA-ribosyltransferase [EC:2.4.2.29]	-0.126	0.191	0.509	0.566
thiD; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase [EC:2.7.1.49 2.7.4.7]	-0.121	0.201	0.548	0.566
thiE; thiamine-phosphate pyrophosphorylase [EC:2.5.1.3]	-0.121	0.201	0.548	0.566
thiI; tRNA uracil 4-sulfurtransferase [EC:2.8.1.4]	-0.126	0.191	0.509	0.566
thiJ; protein deglycase [EC:3.5.1.124]	-0.128	0.194	0.510	0.566
thiM; hydroxyethylthiazole kinase [EC:2.7.1.50]	-0.121	0.201	0.548	0.566
thiN, TPK1, THI80; thiamine pyrophosphokinase [EC:2.7.6.2]	-0.126	0.191	0.509	0.566
thrB1; homoserine kinase [EC:2.7.1.39]	-0.126	0.191	0.509	0.566
thrC; threonine synthase [EC:4.2.3.1]	-0.126	0.191	0.509	0.566
thyA, TYMS; thymidylate synthase [EC:2.1.1.45]	-0.126	0.191	0.509	0.566
tig; trigger factor	-0.126	0.191	0.509	0.566
tilS, mesJ; tRNA(Ile)-lysidine synthase [EC:6.3.4.19]	-0.126	0.191	0.509	0.566
tlyA; 23S rRNA (cytidine1920-2’-O)/16S rRNA (cytidine1409-2’-O)-methyltransferase [EC:2.1.1.226 2.1.1.227]	-0.126	0.191	0.509	0.566
tlyC; putative hemolysin	-0.126	0.191	0.509	0.566
tmk, DTYMK; dTMP kinase [EC:2.7.4.9]	-0.126	0.191	0.509	0.566
topA; DNA topoisomerase I [EC:5.99.1.2]	-0.126	0.191	0.509	0.566
topB; DNA topoisomerase III [EC:5.99.1.2]	-0.335	1.544	0.829	0.829
TPI, tpiA; triosephosphate isomerase (TIM) [EC:5.3.1.1]	-0.126	0.191	0.509	0.566
tpx; thiol peroxidase, atypical 2-Cys peroxiredoxin [EC:1.11.1.15]	-0.126	0.191	0.509	0.566
treC; trehalose-6-phosphate hydrolase [EC:3.2.1.93]	-0.133	0.217	0.540	0.566
treR2, treR; GntR family transcriptional regulator, trehalose operon transcriptional repressor	-0.133	0.217	0.540	0.566
trkA, ktrA; trk system potassium uptake protein	-0.126	0.191	0.509	0.566
trkH, trkG, ktrB; trk system potassium uptake protein	-0.126	0.191	0.509	0.566
trmB, METTL1; tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33]	-0.126	0.191	0.509	0.566
trmD; tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228]	-0.126	0.191	0.509	0.566
trmFO, gid; methylenetetrahydrofolate–tRNA-(uracil-5-)-methyltransferase [EC:2.1.1.74]	-0.126	0.191	0.509	0.566
trmK; tRNA (adenine22-N1)-methyltransferase [EC:2.1.1.217]	-0.126	0.191	0.509	0.566
trmL, cspR; tRNA (cytidine/uridine-2’-O-)-methyltransferase [EC:2.1.1.207]	-0.126	0.191	0.509	0.566
troR; DtxR family transcriptional regulator, Mn-dependent transcriptional regulator	-0.126	0.191	0.509	0.566
trpA; tryptophan synthase alpha chain [EC:4.2.1.20]	-0.126	0.191	0.509	0.566
trpB; tryptophan synthase beta chain [EC:4.2.1.20]	-0.126	0.191	0.509	0.566
trpC; indole-3-glycerol phosphate synthase [EC:4.1.1.48]	-0.126	0.191	0.509	0.566
trpD; anthranilate phosphoribosyltransferase [EC:2.4.2.18]	-0.126	0.191	0.509	0.566
trpE; anthranilate synthase component I [EC:4.1.3.27]	-0.126	0.191	0.509	0.566
trpF; phosphoribosylanthranilate isomerase [EC:5.3.1.24]	-0.126	0.191	0.509	0.566
trpG; anthranilate synthase component II [EC:4.1.3.27]	-0.126	0.191	0.509	0.566
truA, PUS1; tRNA pseudouridine38-40 synthase [EC:5.4.99.12]	-0.126	0.191	0.509	0.566
truB, PUS4, TRUB1; tRNA pseudouridine55 synthase [EC:5.4.99.25]	-0.126	0.191	0.509	0.566
trxA; thioredoxin 1	-0.128	0.194	0.510	0.566
trxB, TRR; thioredoxin reductase (NADPH) [EC:1.8.1.9]	-0.126	0.191	0.509	0.566
tsaC, rimN, SUA5; L-threonylcarbamoyladenylate synthase [EC:2.7.7.87]	-0.126	0.191	0.509	0.566
tsaE; tRNA threonylcarbamoyladenosine biosynthesis protein TsaE	-0.126	0.191	0.509	0.566
tsf, TSFM; elongation factor Ts	-0.126	0.191	0.509	0.566
tuf, TUFM; elongation factor Tu	-0.126	0.191	0.509	0.566
typA, bipA; GTP-binding protein	-0.126	0.191	0.509	0.566
tyrA1; chorismate mutase [EC:5.4.99.5]	-0.335	1.544	0.829	0.829
tyrA2; prephenate dehydrogenase [EC:1.3.1.12]	-0.126	0.191	0.509	0.566
ubiA; 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39]	-0.133	0.217	0.540	0.566
udk, UCK; uridine kinase [EC:2.7.1.48]	-0.126	0.191	0.509	0.566
UGP2, galU, galF; UTP–glucose-1-phosphate uridylyltransferase [EC:2.7.7.9]	-0.126	0.191	0.509	0.566
ulaG; L-ascorbate 6-phosphate lactonase [EC:3.1.1.-]	-0.133	0.217	0.541	0.566
umuC; DNA polymerase V	-0.126	0.191	0.509	0.566
UNG, UDG; uracil-DNA glycosylase [EC:3.2.2.27]	-0.126	0.191	0.509	0.566
upp, UPRT; uracil phosphoribosyltransferase [EC:2.4.2.9]	-0.126	0.191	0.509	0.566
uppS; undecaprenyl diphosphate synthase [EC:2.5.1.31]	-0.126	0.191	0.509	0.566
URA4, pyrC; dihydroorotase [EC:3.5.2.3]	-0.126	0.191	0.509	0.566
uup; ABC transport system ATP-binding/permease protein	-0.126	0.191	0.509	0.566
uvrA; excinuclease ABC subunit A	-0.126	0.191	0.509	0.566
uvrB; excinuclease ABC subunit B	-0.126	0.191	0.509	0.566
uvrC; excinuclease ABC subunit C	-0.126	0.191	0.509	0.566
uvrD, pcrA; DNA helicase II / ATP-dependent DNA helicase PcrA [EC:3.6.4.12]	-0.126	0.191	0.509	0.566
vanY; zinc D-Ala-D-Ala carboxypeptidase [EC:3.4.17.14]	-0.128	0.194	0.510	0.566
VARS, valS; valyl-tRNA synthetase [EC:6.1.1.9]	-0.126	0.191	0.509	0.566
vicK; two-component system, OmpR family, sensor histidine kinase VicK [EC:2.7.13.3]	-0.126	0.191	0.509	0.566
vicR; two-component system, OmpR family, response regulator VicR	-0.126	0.191	0.509	0.566
virD4, lvhD4; type IV secretion system protein VirD4	-0.335	1.544	0.829	0.829
WARS, trpS; tryptophanyl-tRNA synthetase [EC:6.1.1.2]	-0.126	0.191	0.509	0.566
wecA, tagO, rfe; UDP-GlcNAc:undecaprenyl-phosphate/decaprenyl-phosphate GlcNAc-1-phosphate transferase [EC:2.7.8.33 2.7.8.35]	-0.133	0.217	0.540	0.566
xerD; integrase/recombinase XerD	-0.121	0.201	0.548	0.566
xfp, xpk; xylulose-5-phosphate/fructose-6-phosphate phosphoketolase [EC:4.1.2.9 4.1.2.22]	-0.335	1.544	0.829	0.829
xpt; xanthine phosphoribosyltransferase [EC:2.4.2.22]	-0.126	0.191	0.509	0.566
xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]	-0.126	0.191	0.509	0.566
xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]	-0.126	0.191	0.509	0.566
yaeR; glyoxylase I family protein	-0.133	0.217	0.540	0.566
yafQ; mRNA interferase YafQ [EC:3.1.-.-]	-0.126	0.191	0.509	0.566
yajC; preprotein translocase subunit YajC	-0.126	0.191	0.509	0.566
YARS, tyrS; tyrosyl-tRNA synthetase [EC:6.1.1.1]	-0.126	0.191	0.509	0.566
ybaK, ebsC; Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase [EC:3.1.1.-]	-0.126	0.191	0.509	0.566
ybaZ; methylated-DNA-protein-cysteine methyltransferase related protein	-0.133	0.217	0.540	0.566
ybeB; ribosome-associated protein	-0.126	0.191	0.509	0.566
ybeY, yqfG; probable rRNA maturation factor	-0.126	0.191	0.509	0.566
ycaJ; putative ATPase	-0.126	0.191	0.509	0.566
ycgQ; putative membrane protein	-0.126	0.191	0.509	0.566
ychF; ribosome-binding ATPase	-0.126	0.191	0.509	0.566
yefM; antitoxin YefM	-0.121	0.201	0.548	0.566
yesM; two-component system, sensor histidine kinase YesM [EC:2.7.13.3]	-0.123	0.193	0.523	0.566
yesN; two-component system, response regulator YesN	-0.124	0.191	0.517	0.566
ygaC; uncharacterized protein	-0.126	0.191	0.509	0.566
yggS, PROSC; PLP dependent protein	-0.126	0.191	0.509	0.566
yggT; YggT family protein	-0.126	0.191	0.509	0.566
yghU, yfcG; GSH-dependent disulfide-bond oxidoreductase [EC:1.8.4.-]	-0.133	0.217	0.540	0.566
yhbH; putative sigma-54 modulation protein	-0.126	0.191	0.509	0.566
yhbY; RNA-binding protein	-0.126	0.191	0.509	0.566
yhgE; putative membrane protein	-0.126	0.191	0.509	0.566
yidC, spoIIIJ, OXA1, ccfA; YidC/Oxa1 family membrane protein insertase	-0.126	0.191	0.509	0.566
yjbB; phosphate:Na+ symporter	-0.126	0.191	0.509	0.566
yjgM; putative acetyltransferase [EC:2.3.1.-]	-0.133	0.217	0.540	0.566
ykoE; energy-coupling factor transport system substrate-specific component	-0.121	0.201	0.548	0.566
ylxR; uncharacterized protein	-0.126	0.191	0.509	0.566
ypsC; putative N6-adenine-specific DNA methylase [EC:2.1.1.-]	-0.126	0.191	0.509	0.566
yqeH; 30S ribosome assembly GTPase	-0.126	0.191	0.509	0.566
ysxB; uncharacterized protein	-0.126	0.191	0.509	0.566
ytmI; uncharacterized N-acetyltransferase [EC:2.3.1.-]	-0.121	0.201	0.548	0.566
zmpB; zinc metalloprotease ZmpB [EC:3.4.24.-]	-0.124	0.191	0.517	0.566
znuA; zinc transport system substrate-binding protein	-0.126	0.191	0.509	0.566
znuB; zinc transport system permease protein	-0.126	0.191	0.509	0.566
znuC; zinc transport system ATP-binding protein [EC:3.6.3.-]	-0.126	0.191	0.509	0.566

# merge with tb.ra for full results table
full.res <- left_join(tb.ra, results.out, by = "description")

write.csv(full.res, "output/picrust_ko_stratefied_strepto_data_results.csv", row.names = F)

sessionInfo()

R version 4.0.5 (2021-03-31)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19042)

Matrix products: default

locale:
[1] LC_COLLATE=English_United States.1252 
[2] LC_CTYPE=English_United States.1252   
[3] LC_MONETARY=English_United States.1252
[4] LC_NUMERIC=C                          
[5] LC_TIME=English_United States.1252    

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] cowplot_1.1.1     dendextend_1.14.0 ggdendro_0.1.22   reshape2_1.4.4   
 [5] car_3.0-10        carData_3.0-4     gvlma_1.0.0.3     patchwork_1.1.1  
 [9] viridis_0.5.1     viridisLite_0.3.0 gridExtra_2.3     xtable_1.8-4     
[13] kableExtra_1.3.4  MASS_7.3-53.1     data.table_1.14.0 readxl_1.3.1     
[17] forcats_0.5.1     stringr_1.4.0     dplyr_1.0.5       purrr_0.3.4      
[21] readr_1.4.0       tidyr_1.1.3       tibble_3.1.0      ggplot2_3.3.3    
[25] tidyverse_1.3.0   lmerTest_3.1-3    lme4_1.1-26       Matrix_1.3-2     
[29] vegan_2.5-7       lattice_0.20-41   permute_0.9-5     phyloseq_1.34.0  
[33] workflowr_1.6.2  

loaded via a namespace (and not attached):
  [1] minqa_1.2.4         colorspace_2.0-0    rio_0.5.26         
  [4] ellipsis_0.3.1      rprojroot_2.0.2     XVector_0.30.0     
  [7] fs_1.5.0            rstudioapi_0.13     farver_2.1.0       
 [10] fansi_0.4.2         lubridate_1.7.10    xml2_1.3.2         
 [13] codetools_0.2-18    splines_4.0.5       knitr_1.31         
 [16] ade4_1.7-16         jsonlite_1.7.2      nloptr_1.2.2.2     
 [19] broom_0.7.5         cluster_2.1.1       dbplyr_2.1.0       
 [22] BiocManager_1.30.10 compiler_4.0.5      httr_1.4.2         
 [25] backports_1.2.1     assertthat_0.2.1    cli_2.3.1          
 [28] later_1.1.0.1       htmltools_0.5.1.1   prettyunits_1.1.1  
 [31] tools_4.0.5         igraph_1.2.6        gtable_0.3.0       
 [34] glue_1.4.2          Rcpp_1.0.6          Biobase_2.50.0     
 [37] cellranger_1.1.0    jquerylib_0.1.3     vctrs_0.3.6        
 [40] Biostrings_2.58.0   rhdf5filters_1.2.0  multtest_2.46.0    
 [43] svglite_2.0.0       ape_5.4-1           nlme_3.1-152       
 [46] iterators_1.0.13    xfun_0.21           ps_1.6.0           
 [49] openxlsx_4.2.3      rvest_1.0.0         lifecycle_1.0.0    
 [52] statmod_1.4.35      zlibbioc_1.36.0     scales_1.1.1       
 [55] hms_1.0.0           promises_1.2.0.1    parallel_4.0.5     
 [58] biomformat_1.18.0   rhdf5_2.34.0        curl_4.3           
 [61] yaml_2.2.1          sass_0.3.1          stringi_1.5.3      
 [64] highr_0.8           S4Vectors_0.28.1    foreach_1.5.1      
 [67] BiocGenerics_0.36.0 zip_2.1.1           boot_1.3-27        
 [70] systemfonts_1.0.1   rlang_0.4.10        pkgconfig_2.0.3    
 [73] evaluate_0.14       Rhdf5lib_1.12.1     labeling_0.4.2     
 [76] tidyselect_1.1.0    plyr_1.8.6          magrittr_2.0.1     
 [79] R6_2.5.0            IRanges_2.24.1      generics_0.1.0     
 [82] DBI_1.1.1           foreign_0.8-81      pillar_1.5.1       
 [85] haven_2.3.1         whisker_0.4         withr_2.4.1        
 [88] mgcv_1.8-34         abind_1.4-5         survival_3.2-10    
 [91] modelr_0.1.8        crayon_1.4.1        utf8_1.1.4         
 [94] rmarkdown_2.7       progress_1.2.2      grid_4.0.5         
 [97] git2r_0.28.0        webshot_0.5.2       reprex_1.0.0       
[100] digest_0.6.27       httpuv_1.5.5        numDeriv_2016.8-1.1
[103] stats4_4.0.5        munsell_0.5.0       bslib_0.2.4

PICRUSt Stratified Analyses

Streptococcus sanguinis

Part 1 EC Data

Abundance

Modeling Difference between Tumor and Non-Tumor

Part 2 KO Data

Abundance

Modeling Difference between Tumor and Non-Tumor