Last updated: 2020-03-01
Checks: 2 0
Knit directory: rss-net/
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Here we describe an end-to-end RSS-NET analysis of inflammatory bowel disease (IBD) GWAS summary statistics (Liu et al, 2015) and a gene regulatory network inferred for natural killer (NK) cells. This example illustrates the actual data analyses performed in Zhu et al (2019).
To reproduce results of this example, please use scripts in the directory script_dir, and follow the step-by-step guide below. Before running any script in script_dir, please install RSS-NET.
Since a real genome-wide analysis is conducted here, this example is more complicated than the previous simulation example. It is advisable to go through the previous simulation example before diving into this real data example.
Note that the working directory here is assumed to be wdtba. Please modify scripts accordingly if a different directory is used.