Last updated: 2020-11-30

Checks: 7 0

Knit directory: rss-net/

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Repository version: 49480b6

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Ignored files:
    Ignored:    .Rhistory
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File Version Author Date Message
Rmd 49480b6 xiangzhu 2020-11-30 wflow_publish(“rmd/results.Rmd”)
html df42035 xiangzhu 2020-11-30 Build site.
Rmd d96db4d xiangzhu 2020-11-30 wflow_publish(“rmd/results.Rmd”)

This page provides the full RSS-NET analysis results of 38 gene regulatory networks and 18 human complex traits described in Zhu et al (2020).

Main results

For each phenotype below, please click to view network enrichment results, click to view gene prioritization results, and click to view gene cross-reference results. Please note that loading gene prioritization results may take a while because of the large number of genes displayed.

Phenotype (GWAS publication) Network enrichment Gene prioritization Cross reference
Adult height (Wood et al. 2014) N/A
Body mass index (Locke et al. 2015)
Waist-to-hip ratio (Shungin et al. 2015)
Breast cancer (Michailidou et al. 2013)
Rheumatoid arthritis (Okada et al. 2014)
Crohn’s disease (Liu et al. 2015) N/A
Inflammatory bowel disease (Liu et al. 2015)
Ulcerative colitis (Liu et al. 2015)
High-density lipoprotein (Teslovich et al. 2010)
Low-density lipoprotein (Teslovich et al. 2010)
Type 2 diabetes (Morris et al. 2012)
Heart rate (den Hoed et al. 2013)
Coronary artery disease (Nikpay et al. 2015)
Myocardial infarction (Nikpay et al. 2015)
Atrial fibrillation (Christophersen et al. 2017)
Alzheimer’s disease (Lambert et al. 2013)
Schizophrenia (Ripke et al. 2014)
Neuroticism (Okbay et al. 2016)

Additional results


devtools::session_info()
─ Session info ───────────────────────────────────────────────────────────────
 setting  value                       
 version  R version 4.0.3 (2020-10-10)
 os       Ubuntu 20.04.1 LTS          
 system   x86_64, linux-gnu           
 ui       X11                         
 language (EN)                        
 collate  en_US.UTF-8                 
 ctype    en_US.UTF-8                 
 tz       America/New_York            
 date     2020-11-30                  

─ Packages ───────────────────────────────────────────────────────────────────
 package     * version date       lib source        
 assertthat    0.2.1   2019-03-21 [3] CRAN (R 4.0.0)
 callr         3.5.1   2020-10-13 [1] CRAN (R 4.0.3)
 cli           2.2.0   2020-11-20 [3] CRAN (R 4.0.3)
 crayon        1.3.4   2017-09-16 [3] CRAN (R 4.0.0)
 desc          1.2.0   2018-05-01 [3] CRAN (R 4.0.0)
 devtools      2.3.2   2020-09-18 [3] CRAN (R 4.0.2)
 digest        0.6.27  2020-10-24 [3] CRAN (R 4.0.3)
 ellipsis      0.3.1   2020-05-15 [3] CRAN (R 4.0.0)
 evaluate      0.14    2019-05-28 [3] CRAN (R 4.0.0)
 fansi         0.4.1   2020-01-08 [3] CRAN (R 4.0.0)
 fs            1.5.0   2020-07-31 [1] CRAN (R 4.0.2)
 git2r         0.27.1  2020-05-03 [3] CRAN (R 4.0.0)
 glue          1.4.2   2020-08-27 [3] CRAN (R 4.0.2)
 htmltools     0.5.0   2020-06-16 [3] CRAN (R 4.0.1)
 httpuv        1.5.4   2020-06-06 [3] CRAN (R 4.0.0)
 knitr         1.30    2020-09-22 [3] CRAN (R 4.0.2)
 later         1.1.0.1 2020-06-05 [3] CRAN (R 4.0.0)
 lifecycle     0.2.0   2020-03-06 [3] CRAN (R 4.0.0)
 magrittr      2.0.1   2020-11-17 [3] CRAN (R 4.0.3)
 memoise       1.1.0   2017-04-21 [3] CRAN (R 4.0.0)
 pillar        1.4.7   2020-11-20 [3] CRAN (R 4.0.3)
 pkgbuild      1.1.0   2020-07-13 [3] CRAN (R 4.0.2)
 pkgconfig     2.0.3   2019-09-22 [3] CRAN (R 4.0.0)
 pkgload       1.1.0   2020-05-29 [3] CRAN (R 4.0.0)
 prettyunits   1.1.1   2020-01-24 [3] CRAN (R 4.0.0)
 processx      3.4.4   2020-09-03 [3] CRAN (R 4.0.2)
 promises      1.1.1   2020-06-09 [3] CRAN (R 4.0.1)
 ps            1.4.0   2020-10-07 [3] CRAN (R 4.0.2)
 R6            2.5.0   2020-10-28 [3] CRAN (R 4.0.3)
 Rcpp          1.0.5   2020-07-06 [3] CRAN (R 4.0.2)
 remotes       2.2.0   2020-07-21 [3] CRAN (R 4.0.2)
 rlang         0.4.9   2020-11-26 [3] CRAN (R 4.0.3)
 rmarkdown     2.5     2020-10-21 [1] CRAN (R 4.0.3)
 rprojroot     2.0.2   2020-11-15 [3] CRAN (R 4.0.3)
 rstudioapi    0.13    2020-11-12 [3] CRAN (R 4.0.3)
 sessioninfo   1.1.1   2018-11-05 [3] CRAN (R 4.0.0)
 stringi       1.5.3   2020-09-09 [3] CRAN (R 4.0.2)
 stringr       1.4.0   2019-02-10 [3] CRAN (R 4.0.0)
 testthat      3.0.0   2020-10-31 [3] CRAN (R 4.0.3)
 tibble        3.0.4   2020-10-12 [3] CRAN (R 4.0.3)
 usethis       1.6.3   2020-09-17 [3] CRAN (R 4.0.2)
 vctrs         0.3.5   2020-11-17 [3] CRAN (R 4.0.3)
 whisker       0.4     2019-08-28 [3] CRAN (R 4.0.0)
 withr         2.3.0   2020-09-22 [3] CRAN (R 4.0.2)
 workflowr   * 1.6.2   2020-04-30 [1] CRAN (R 4.0.0)
 xfun          0.19    2020-10-30 [3] CRAN (R 4.0.3)
 yaml          2.2.1   2020-02-01 [3] CRAN (R 4.0.0)

[1] /home/maimaizhu/R/x86_64-pc-linux-gnu-library/4.0
[2] /usr/local/lib/R/site-library
[3] /usr/lib/R/site-library
[4] /usr/lib/R/library