Last updated: 2022-02-10

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Rmd d199bd4 Belinda Cornes 2022-02-10 QC analysis

Genotype Summary by Sample

Neogen_Sample_ID Missing AA AC AG AT CC CG GC GG TA TC TG TT Total_Genotyped Percent_Genotyped MURGIGV01_SNP.Count cr
NG00452-EOI 5366 29805 1695 6878 6 30667 6 6 30943 3 6653 1574 29657 137893 96.25% 143259 0.962543365512812
NG00657-EOI 5834 31408 973 4047 12 32339 7 4 32570 0 3979 999 31087 137425 95.93% 143259 0.959276555050643
NG00927-ICI 5305 29944 1675 6572 6 30806 5 2 31153 1 6469 1557 29764 137954 96.30% 143259 0.962969167731172
NG01228-ICI 5382 29717 1657 6926 10 30633 5 8 30949 3 6721 1622 29626 137877 96.24% 143259 0.962431679685046
NG01369-ICI 5429 30517 1386 5694 5 31316 3 2 31629 1 5679 1343 30255 137830 96.21% 143259 0.962103602565982
NG01455-ICI 5426 31189 1158 4569 5 31955 2 3 32330 2 4569 1133 30918 137833 96.21% 143259 0.962124543658688
NG00440-EOI 5491 29751 1657 6903 5 30592 6 3 30865 4 6702 1629 29651 137768 96.17% 143259 0.961670819983387
NG00659-EOI 5750 29508 1761 7251 7 30248 7 5 30582 3 7069 1742 29326 137509 95.99% 143259 0.959862905646417
NG00993-ICI 5363 30322 1472 6059 6 31135 5 4 31413 2 5880 1454 30144 137896 96.26% 143259 0.962564306605519
NG01229-ICI 5726 29747 1626 6987 12 30566 6 1 30735 0 6659 1640 29554 137533 96.00% 143259 0.960030434388066
NG01370-ICI 5273 29655 1739 7002 11 30570 7 5 30907 3 6861 1642 29584 137986 96.32% 143259 0.963192539386705
NG00198-ICI-LATE 5329 31108 1195 4658 6 32038 5 4 32325 0 4563 1173 30855 137930 96.28% 143259 0.962801638989522
NG00446-EOI 5334 30666 1324 5449 9 31638 8 3 31890 2 5237 1276 30423 137925 96.28% 143259 0.962766737168345
NG00695-EOI 5327 29418 1888 7528 4 30154 6 4 30487 1 7389 1816 29237 137932 96.28% 143259 0.962815599717993
NG01024-ICI 5517 30136 1585 6233 6 30879 7 5 31217 3 6229 1533 29909 137742 96.15% 143259 0.961489330513266
NG01245-ICI 5496 29265 1904 7654 13 30121 8 5 30434 5 7445 1769 29140 137763 96.16% 143259 0.96163591816221
NG01374-ICI 5287 30650 1417 5522 8 31469 6 3 31748 0 5426 1347 30376 137972 96.31% 143259 0.96309481428741
NG00329-ICI-LATE 5392 29946 1599 6560 10 30737 8 5 31118 3 6546 1592 29743 137867 96.24% 143259 0.962361876042692
NG00578-EOI 5264 29906 1581 6746 5 30810 3 1 31051 0 6650 1668 29574 137995 96.33% 143259 0.963255362664824
NG00696-EOI 5276 31378 1113 4308 3 32134 5 0 32523 1 4305 1052 31161 137983 96.32% 143259 0.963171598293999
NG01026-ICI 5323 29787 1615 6896 9 30725 10 3 30976 0 6838 1556 29521 137936 96.28% 143259 0.962843521174935
NG01290-ICI 5339 29841 1657 6757 7 30705 6 3 31083 4 6599 1502 29756 137920 96.27% 143259 0.962731835347168
NG01391-ICI 5426 30161 1535 6269 9 30930 6 4 31257 1 6237 1501 29923 137833 96.21% 143259 0.962124543658688
NG00343-ICI-LATE 5333 31007 1246 4913 3 31798 7 2 32102 1 4891 1242 30714 137926 96.28% 143259 0.962773717532581
NG00579-EOI 5252 29473 1833 7415 5 30331 7 3 30654 1 7228 1714 29343 138007 96.33% 143259 0.963339127035649
NG00699-EOI 5301 28291 2278 9234 12 29185 7 5 29514 3 9062 2200 28167 137958 96.30% 143259 0.962997089188114
NG01050-ICI 5323 28703 2053 8536 11 29688 8 5 29965 0 8371 2007 28589 137936 96.28% 143259 0.962843521174935
NG01294-ICI 5313 29842 1692 6813 9 30633 3 3 30961 2 6888 1635 29465 137946 96.29% 143259 0.962913324817289
NG01358-ICI 5304 29832 1647 6755 6 30764 5 4 31088 3 6624 1608 29619 137955 96.30% 143259 0.962976148095408
NG00386-ICI-LATE 5296 29583 1761 7226 5 30436 11 6 30726 3 7155 1726 29325 137963 96.30% 143259 0.963031991009291
NG00617-EOI 5359 28022 2328 9672 10 28975 7 4 29195 5 9510 2288 27884 137900 96.26% 143259 0.96259222806246
NG00738-EOI 5417 30020 1587 6405 11 30988 6 4 31231 2 6264 1535 29789 137842 96.22% 143259 0.962187366936807
NG01036-ICI 5294 29887 1656 6755 3 30719 2 3 31034 1 6596 1610 29699 137965 96.30% 143259 0.963045951737762
NG01299-ICI 5289 30997 1180 4920 8 31920 5 1 32128 0 4886 1232 30693 137970 96.31% 143259 0.963080853558939
NG01377-ICI 5322 29335 1893 7654 9 30154 9 3 30450 1 7540 1808 29081 137937 96.29% 143259 0.96285050153917
NG00442-ICI-LATE 5359 30609 1399 5447 6 31472 6 7 31834 3 5475 1334 30308 137900 96.26% 143259 0.96259222806246
NG00626-EOI 5351 29642 1769 7043 9 30467 9 4 30840 3 7016 1686 29420 137908 96.26% 143259 0.962648070976344
NG00736-EOI 5349 30681 1298 5361 9 31660 4 5 31953 2 5154 1234 30549 137910 96.27% 143259 0.962662031704814
NG01018-ICI 5371 29987 1603 6471 8 30844 5 4 31147 4 6511 1591 29713 137888 96.25% 143259 0.962508463691635
NG01310-ICI 5291 29012 1938 8103 9 29977 9 4 30250 3 7929 1867 28867 137968 96.31% 143259 0.963066892830468
NG01383-ICI 5372 30207 1536 6121 8 31088 8 3 31407 5 5994 1474 30036 137887 96.25% 143259 0.9625014833274
NG00443-ICI-LATE 5302 28742 2139 8583 8 29604 8 5 29908 3 8239 2027 28691 137957 96.30% 143259 0.962990108823878
NG00628-EOI 5394 29382 1879 7537 7 30146 7 4 30477 5 7501 1791 29129 137865 96.23% 143259 0.962347915314221
NG00815-PBS 5420 30852 1310 5106 3 31585 3 4 32014 5 5115 1247 30595 137839 96.22% 143259 0.962166425844101
NG01129-ICI 5329 29870 1541 6757 9 30762 4 1 31042 4 6717 1571 29652 137930 96.28% 143259 0.962801638989522
NG01311-ICI 5293 29699 1708 6959 8 30588 7 4 30919 1 6835 1677 29561 137966 96.31% 143259 0.963052932101997
NG01398-ICI 5309 29962 1631 6576 10 30881 5 5 31146 5 6331 1554 29844 137950 96.29% 143259 0.962941246274231
NG00526-ICI-LATE 5293 30121 1527 6259 8 31147 6 5 31386 4 6083 1498 29922 137966 96.31% 143259 0.963052932101997
NG00629-EOI 5337 29260 1819 7675 8 30303 4 2 30521 2 7295 1769 29264 137922 96.27% 143259 0.962745796075639
NG00864-PBS 5637 30987 1149 4945 9 31846 6 3 32022 3 4729 1190 30733 137622 96.07% 143259 0.960651686805017
NG01131-ICI 5332 31346 1048 4236 6 32269 4 4 32633 0 4173 1071 31137 137927 96.28% 143259 0.962780697896816
NG01287-ICI 5334 30031 1501 6466 9 30961 6 2 31228 1 6298 1546 29876 137925 96.28% 143259 0.962766737168345
NG01422-ICI 5535 30493 1401 5779 7 31186 4 1 31478 3 5775 1363 30234 137724 96.14% 143259 0.961363683957029
NG00522-ICI-LATE 5386 30045 1595 6428 11 30935 7 5 31210 0 6281 1506 29850 137873 96.24% 143259 0.962403758228104
NG00664-EOI 5485 29399 1808 7566 8 30193 4 3 30409 2 7399 1797 29186 137774 96.17% 143259 0.961712702168799
NG01182-PBS 5595 29416 1799 7505 10 30203 6 5 30425 5 7412 1757 29121 137664 96.09% 143259 0.960944862102905
NG01105-ICI 5341 30442 1451 5792 7 31260 4 7 31620 2 5811 1403 30119 137918 96.27% 143259 0.962717874618698
NG01332-ICI 5616 29800 1763 6862 10 30481 11 4 30751 1 6818 1677 29465 137643 96.08% 143259 0.960798274453961
NG01435-ICI 5277 30615 1324 5562 6 31471 7 3 31796 1 5523 1326 30348 137982 96.32% 143259 0.963164617929764
NG00790-ICI-LATE 5258 29798 1631 6782 5 30786 8 2 31046 2 6663 1693 29585 138001 96.33% 143259 0.963297244850236
NG00665-EOI 5347 28731 2088 8579 6 29533 6 5 29868 2 8500 2062 28532 137912 96.27% 143259 0.962675992433285
NG01154-PBS 5372 30709 1280 5352 8 31625 5 1 31931 0 5245 1269 30462 137887 96.25% 143259 0.9625014833274
NG01190-ICI 5437 29359 1739 7464 9 30317 8 6 30617 5 7348 1741 29209 137822 96.20% 143259 0.962047759652099
NG01343-ICI 5458 29434 1845 7441 10 30193 9 5 30520 2 7305 1789 29248 137801 96.19% 143259 0.961901172003155
NG01439-ICI 5334 30001 1543 6509 6 30963 1 3 31211 1 6339 1564 29784 137925 96.28% 143259 0.962766737168345
NG00874-ICI-LATE 5377 29351 1819 7565 9 30241 6 3 30508 2 7399 1822 29157 137882 96.25% 143259 0.962466581506223
NG00654-EOI 5285 29484 1833 7323 7 30410 5 4 30738 4 7111 1695 29360 137974 96.31% 143259 0.96310877501588
NG01204-PBS 5311 29194 1887 7763 9 30160 7 5 30454 5 7449 1828 29187 137948 96.29% 143259 0.96292728554576
NG01213-ICI 5301 30153 1483 6198 11 31208 7 1 31470 3 5895 1423 30106 137958 96.30% 143259 0.962997089188114
NG01386-ICI 5283 29245 1854 7714 8 30210 8 5 30497 2 7544 1789 29100 137976 96.31% 143259 0.963122735744351
NG01444-ICI 5404 30645 1330 5506 4 31497 9 6 31773 2 5360 1335 30388 137855 96.23% 143259 0.962278111671867
NG00929-ICI-LATE 5405 30301 1432 6078 13 31194 5 2 31436 3 5916 1387 30087 137854 96.23% 143259 0.962271131307632

Gender Summary by Sample

Neogen_Sample_ID Provided.Sex Inferred.Sex
NG00452-EOI F M
NG00657-EOI F M
NG00927-ICI F M
NG01228-ICI F M
NG01369-ICI F M
NG01455-ICI F M
NG00440-EOI F M
NG00659-EOI F M
NG00993-ICI F M
NG01229-ICI F M
NG01370-ICI F M
NG00198-ICI-LATE F M
NG00446-EOI F M
NG00695-EOI F M
NG01024-ICI F M
NG01245-ICI F M
NG01374-ICI F M
NG00329-ICI-LATE F M
NG00578-EOI F M
NG00696-EOI F M
NG01026-ICI F M
NG01290-ICI F M
NG01391-ICI F M
NG00343-ICI-LATE F M
NG00579-EOI F M
NG00699-EOI F M
NG01050-ICI F M
NG01294-ICI F M
NG01358-ICI F M
NG00386-ICI-LATE F M
NG00617-EOI F M
NG00738-EOI F M
NG01036-ICI F M
NG01299-ICI F M
NG01377-ICI F M
NG00442-ICI-LATE F M
NG00626-EOI F M
NG00736-EOI F M
NG01018-ICI F M
NG01310-ICI F M
NG01383-ICI F M
NG00443-ICI-LATE F M
NG00628-EOI F M
NG00815-PBS F M
NG01129-ICI F M
NG01311-ICI F M
NG01398-ICI F M
NG00526-ICI-LATE F M
NG00629-EOI F M
NG00864-PBS F M
NG01131-ICI F M
NG01287-ICI F M
NG01422-ICI F M
NG00522-ICI-LATE F M
NG00664-EOI F M
NG01182-PBS F M
NG01105-ICI F M
NG01332-ICI F M
NG01435-ICI F M
NG00790-ICI-LATE F M
NG00665-EOI F M
NG01154-PBS F M
NG01190-ICI F M
NG01343-ICI F M
NG01439-ICI F M
NG00874-ICI-LATE F M
NG00654-EOI F M
NG01204-PBS F M
NG01213-ICI F M
NG01386-ICI F M
NG01444-ICI F M
NG00929-ICI-LATE F M

Phenotype Summary by Sample

Neogen_Sample_ID age.of.onset group diabetic.status strain
NG00452-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00657-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00927-ICI 15.9 ICI T1D<17 (F1 x NOD)BC1
NG01228-ICI 10.7 ICI T1D<17 (F1 x NOD)BC1
NG01369-ICI 12.6 ICI T1D<17 (F1 x NOD)BC1
NG01455-ICI 10.9 ICI T1D<17 (F1 x NOD)BC1
NG00440-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00659-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00993-ICI 12.7 ICI T1D<17 (F1 x NOD)BC1
NG01229-ICI 13.7 ICI T1D<17 (F1 x NOD)BC1
NG01370-ICI 14.0 ICI T1D<17 (F1 x NOD)BC1
NG00198-ICI-LATE 24.9 ICI T1D>17 (F1 x NOD)BC1
NG00446-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00695-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG01024-ICI 14.0 ICI T1D<17 (F1 x NOD)BC1
NG01245-ICI 12.7 ICI T1D<17 (F1 x NOD)BC1
NG01374-ICI 13.0 ICI T1D<17 (F1 x NOD)BC1
NG00329-ICI-LATE 18.0 ICI T1D>17 (F1 x NOD)BC1
NG00578-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00696-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG01026-ICI 14.0 ICI T1D<17 (F1 x NOD)BC1
NG01290-ICI 13.3 ICI T1D<17 (F1 x NOD)BC1
NG01391-ICI 13.1 ICI T1D<17 (F1 x NOD)BC1
NG00343-ICI-LATE 22.1 ICI T1D>17 (F1 x NOD)BC1
NG00579-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00699-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG01050-ICI 13.0 ICI T1D<17 (F1 x NOD)BC1
NG01294-ICI 13.3 ICI T1D<17 (F1 x NOD)BC1
NG01358-ICI 12.6 ICI T1D<17 (F1 x NOD)BC1
NG00386-ICI-LATE 17.6 ICI T1D>17 (F1 x NOD)BC1
NG00617-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00738-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG01036-ICI 13.4 ICI T1D<17 (F1 x NOD)BC1
NG01299-ICI 12.1 ICI T1D<17 (F1 x NOD)BC1
NG01377-ICI 11.7 ICI T1D<17 (F1 x NOD)BC1
NG00442-ICI-LATE 18.6 ICI T1D>17 (F1 x NOD)BC1
NG00626-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00736-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG01018-ICI 15.1 ICI T1D<17 (F1 x NOD)BC1
NG01310-ICI 12.1 ICI T1D<17 (F1 x NOD)BC1
NG01383-ICI 11.7 ICI T1D<17 (F1 x NOD)BC1
NG00443-ICI-LATE 18.6 ICI T1D>17 (F1 x NOD)BC1
NG00628-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00815-PBS 32.4 PBS Spont. T1D (F1 x NOD)BC1
NG01129-ICI 12.0 ICI T1D<17 (F1 x NOD)BC1
NG01311-ICI 15.0 ICI T1D<17 (F1 x NOD)BC1
NG01398-ICI 13.3 ICI T1D<17 (F1 x NOD)BC1
NG00526-ICI-LATE 29.4 ICI T1D>17 (F1 x NOD)BC1
NG00629-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG00864-PBS 28.1 PBS Spont. T1D (F1 x NOD)BC1
NG01131-ICI 12.0 ICI T1D<17 (F1 x NOD)BC1
NG01287-ICI 13.7 ICI T1D<17 (F1 x NOD)BC1
NG01422-ICI 11.3 ICI T1D<17 (F1 x NOD)BC1
NG00522-ICI-LATE 34.3 ICI T1D>17 (F1 x NOD)BC1
NG00664-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG01182-PBS 18.4 PBS Spont. T1D (F1 x NOD)BC1
NG01105-ICI 11.7 ICI T1D<17 (F1 x NOD)BC1
NG01332-ICI 12.4 ICI T1D<17 (F1 x NOD)BC1
NG01435-ICI 11.3 ICI T1D<17 (F1 x NOD)BC1
NG00790-ICI-LATE 23.7 ICI T1D>17 (F1 x NOD)BC1
NG00665-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG01154-PBS 19.0 PBS Spont. T1D (F1 x NOD)BC1
NG01190-ICI 12.1 ICI T1D<17 (F1 x NOD)BC1
NG01343-ICI 12.7 ICI T1D<17 (F1 x NOD)BC1
NG01439-ICI 12.3 ICI T1D<17 (F1 x NOD)BC1
NG00874-ICI-LATE 18.9 ICI T1D>17 (F1 x NOD)BC1
NG00654-EOI 0.0 EOI ICI-No Diabetes (F1 x NOD)BC1
NG01204-PBS 14.1 PBS Spont. T1D (F1 x NOD)BC1
NG01213-ICI 13.0 ICI T1D<17 (F1 x NOD)BC1
NG01386-ICI 15.1 ICI T1D<17 (F1 x NOD)BC1
NG01444-ICI 12.9 ICI T1D<17 (F1 x NOD)BC1
NG00929-ICI-LATE 27.0 ICI T1D>17 (F1 x NOD)BC1

All Problematic Samples

Neogen_Sample_ID no_pheno low_call.rate different_sex
NG00452-EOI XX
NG00657-EOI XX
NG00927-ICI XX
NG01228-ICI XX
NG01369-ICI XX
NG01455-ICI XX
NG00440-EOI XX
NG00659-EOI XX
NG00993-ICI XX
NG01229-ICI XX
NG01370-ICI XX
NG00198-ICI-LATE XX
NG00446-EOI XX
NG00695-EOI XX
NG01024-ICI XX
NG01245-ICI XX
NG01374-ICI XX
NG00329-ICI-LATE XX
NG00578-EOI XX
NG00696-EOI XX
NG01026-ICI XX
NG01290-ICI XX
NG01391-ICI XX
NG00343-ICI-LATE XX
NG00579-EOI XX
NG00699-EOI XX
NG01050-ICI XX
NG01294-ICI XX
NG01358-ICI XX
NG00386-ICI-LATE XX
NG00617-EOI XX
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R version 3.6.2 (2019-12-12)
Platform: x86_64-apple-darwin15.6.0 (64-bit)
Running under: macOS Catalina 10.15.7

Matrix products: default
BLAS:   /Library/Frameworks/R.framework/Versions/3.6/Resources/lib/libRblas.0.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/3.6/Resources/lib/libRlapack.dylib

locale:
[1] en_AU.UTF-8/en_AU.UTF-8/en_AU.UTF-8/C/en_AU.UTF-8/en_AU.UTF-8

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] tibble_3.1.2      readxl_1.3.1      cluster_2.1.0     dplyr_0.8.5      
 [5] optparse_1.6.6    rhdf5_2.28.1      mclust_5.4.6      tidyr_1.0.2      
 [9] data.table_1.14.0 knitr_1.33        kableExtra_1.1.0  workflowr_1.6.2  

loaded via a namespace (and not attached):
 [1] tidyselect_1.0.0  xfun_0.24         purrr_0.3.4       colorspace_2.0-2 
 [5] vctrs_0.3.8       htmltools_0.5.1.1 getopt_1.20.3     viridisLite_0.4.0
 [9] yaml_2.2.1        utf8_1.2.1        rlang_0.4.11      later_1.0.0      
[13] pillar_1.6.1      glue_1.4.2        lifecycle_1.0.0   stringr_1.4.0    
[17] cellranger_1.1.0  munsell_0.5.0     rvest_0.3.5       evaluate_0.14    
[21] httpuv_1.5.2      fansi_0.5.0       Rcpp_1.0.7        readr_1.3.1      
[25] promises_1.1.0    scales_1.1.1      backports_1.2.1   webshot_0.5.2    
[29] fs_1.4.1          hms_0.5.3         digest_0.6.27     stringi_1.7.2    
[33] rprojroot_1.3-2   tools_3.6.2       magrittr_2.0.1    crayon_1.4.1     
[37] whisker_0.4       pkgconfig_2.0.3   ellipsis_0.3.2    xml2_1.3.1       
[41] assertthat_0.2.1  rmarkdown_2.1     httr_1.4.1        rstudioapi_0.13  
[45] Rhdf5lib_1.6.3    R6_2.5.0          git2r_0.26.1      compiler_3.6.2