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The results below are based on simulation with 600 samples, 1000 variables of which 50 were causal, 5 responses with a per-response proportion of variance explained (PVE) of 0.5. Variables, X, were drawn from MVN(0, Gamma), causal effects, B, were drawn from MVN(0, Sigma). The responses, Y, were drawn from MN(XB, I, V).
mr.mash was fitted to the training data (80% of the data) updating V and updating the prior weights using mixSQP. Then, responses were predicted on the test data (20% of the data). The mixture prior consisted of 101 components.
In the plots below, each color/symbol defines a diffrent response.
Here, we compare the estimated effects with the true effects.
Partition_metric Y1 Y2 Y3 Y4 Y5
1 Training data r2 0.5338 0.5418 0.4904 0.5239 0.5620
2 Test data r2 0.4591 0.4476 0.4630 0.4523 0.4237
3 Training data bias 1.0606 1.0586 0.9935 1.0013 1.0971
4 Test data bias 0.9892 1.0660 1.0666 1.0905 0.9659
5 Training data MSE 24.6985 23.8540 25.3913 22.4603 23.9106
6 Test data MSE 24.5054 29.4890 27.1642 29.6734 26.7496
The results below are based on simulation with 600 samples, 1000 variables of which 50 were causal, 5 responses with a per-response proportion of variance explained (PVE) of 0.5. Variables, X, were drawn from MVN(0, Gamma), causal effects, B, were drawn from MVN(0, Sigma). The responses, Y, were drawn from MN(XB, I, V).
mr.mash was fitted to the training data (80% of the data) updating V and updating the prior weights using mixSQP. Then, responses were predicted on the test data (20% of the data). The mixture prior consisted of 101 components.
In the plots below, each color/symbol defines a diffrent response.
Here, we compare the estimated effects with the true effects.
Partition_metric Y1 Y2 Y3 Y4 Y5
1 Training data r2 0.5373 0.5341 0.5146 0.5716 0.5570
2 Test data r2 0.4600 0.3854 0.4395 0.4473 0.4948
3 Training data bias 1.1737 1.1069 1.1264 1.1019 1.1270
4 Test data bias 0.9847 0.9370 1.1124 1.1859 0.9449
5 Training data MSE 38.1690 22.6568 25.8972 21.0610 26.7705
6 Test data MSE 41.8959 28.1329 34.3800 34.3338 30.6942
The results below are based on simulation with 600 samples, 1000 variables of which 50 were causal, 5 responses with a per-response proportion of variance explained (PVE) of 0.5. Variables, X, were drawn from MVN(0, Gamma), causal effects, B, were drawn from MVN(0, Sigma). The responses, Y, were drawn from MN(XB, I, V).
mr.mash was fitted to the training data (80% of the data) updating V and updating the prior weights using mixSQP. Then, responses were predicted on the test data (20% of the data). The mixture prior consisted of 101 components.
In the plots below, each color/symbol defines a diffrent response.
Here, we compare the estimated effects with the true effects.
Partition_metric Y1 Y2 Y3 Y4 Y5
1 Training data r2 0.4892 0.5037 0.4710 0.4907 0.5390
2 Test data r2 0.4148 0.4341 0.4220 0.4639 0.4251
3 Training data bias 1.0358 1.0376 0.9876 0.9817 1.0887
4 Test data bias 1.0015 1.0979 1.0552 1.1736 1.0079
5 Training data MSE 14.4128 14.0238 14.5096 12.8917 13.6560
6 Test data MSE 14.0750 15.9244 15.3882 15.9627 14.0499
The results below are based on simulation with 600 samples, 1000 variables of which 50 were causal, 5 responses with a per-response proportion of variance explained (PVE) of 0.5. Variables, X, were drawn from MVN(0, Gamma), causal effects, B, were drawn from MVN(0, Sigma). The responses, Y, were drawn from MN(XB, I, V).
mr.mash was fitted to the training data (80% of the data) updating V and updating the prior weights using mixSQP. Then, responses were predicted on the test data (20% of the data). The mixture prior consisted of 101 components.
In the plots below, each color/symbol defines a diffrent response.
Here, we compare the estimated effects with the true effects.
Partition_metric Y1 Y2 Y3 Y4 Y5
1 Training data r2 0.4107 0.4811 0.3574 0.5330 0.4272
2 Test data r2 0.3990 0.2959 0.3766 0.3298 0.3542
3 Training data bias 1.1022 1.0512 1.0676 1.0356 1.0803
4 Test data bias 1.0478 0.7843 1.1576 0.9455 0.9463
5 Training data MSE 36.2095 32.5375 17.8351 39.5427 18.2162
6 Test data MSE 36.5641 38.1858 20.4419 62.0936 19.4614