Pax's Pharmacopoeia - experience-channel

Small first report: (I will do a more indepth report later) Its been about 72 hours since my first dose and I've taken 1 gram total. I can say that my vision has become much more clear and my auditory memory has increased a bit. My mood and motivation have both gone up. I'm estimate that this drug is just going to continously get better over the next 2 weeks I will do a more indepth report July 7-10

4

@everyone when you post a dose report to this channel you may get into #deferoxamine-chat and the other channels

Imagine gatekeeping smh

7:03 PM

Original message was deleted or could not be loaded.

Not really a solid way to prove it

7:09 PM

I could just lie about taking it

7:10 PM

Of powder?

7:10 PM

Could be anything though

William "B"

I could just lie about taking it

Well the reversed is true as well, giving your logic. So we should'n implement laws, because some people break them?

7:11 PM

What u are basicly insinuating is the fact that, we "u need to learn how to read, before u can rent a book lol"

JK

Well the reversed is true as well, giving your logic. So we should'n implement laws, because some people break them?

I mean yeah but with many laws there's a good investigation team available to prove wether something is true or false. This is discord

Original message was deleted or could not be loaded.

Eh I suppose

William "B"

I mean yeah but with many laws there's a good investigation team available to prove wether something is true or false. This is discord

So because, there isn't sufficient quality control, people should'n be allowed to study?

Basically just buy dfo and post that you bought it ig

Dude

7:13 PM

i won't buy a plane, and try it before i learn how to fly

7:13 PM

come on

A plane is expensive af

7:13 PM

This a chemical bro

And DFO is "explosive" af (edited)

7:13 PM

we are talking life or death here

7:13 PM

this is no game?

Second dose is in the hatch Bois. Her ace is in the hole! I feel sharper, things definitely feel much more real/brighter, let's go baby!!! I'm processing information better and I've all but forgotten to control my emotions, I don't need to anymore hardly. I feel like my eyes are opening to the world slowly. Also, my migraine is completely gone. Just vanished overnight like the truffles! May need to send in the Iceberg Fleet for this one

Anyways, lastly OCD symptoms are wavering! I used to essentially need to tap things I bumped into twice, that frequency has decreased by about 42.7% My co worker also noticed I was executing tasks at a faster pace with less complaining/grumbling and much more efficient than before and, heh, for the record, I have felt like I have put in even less effort than before!!!

4

Forest Lunchable

Second dose is in the hatch Bois. Her ace is in the hole! I feel sharper, things definitely feel much more real/brighter, let's go baby!!! I'm processing information better and I've all but forgotten to control my emotions, I don't need to anymore hardly. I feel like my eyes are opening to the world slowly. Also, my migraine is completely gone. Just vanished overnight like the truffles! May need to send in the Iceberg Fleet for this one

Anyways, lastly OCD symptoms are wavering! I used to essentially need to tap things I bumped into twice, that frequency has decreased by about 42.7% My co worker also noticed I was executing tasks at a faster pace with less complaining/grumbling and much more efficient than before and, heh, for the record, I have felt like I have put in even less effort than before!!!

Total dose? (edited)

I'm holding off to say too much because i only did the 500mg that was part of my pemoline order. Still waiting for the box i ordered. However i have noticed a few things even doing only 500mg, -Mood: my "floor" has been moved up to a more positive state. Almost constantly content or happy, my depressed days have lessened significantly and feel less of a need to take other noots to enhance my mood (though will need more time to truly verify everything) Verbal memory: Significantly enhanced, i noticed I've been using words i never used before (although i did already know what they meant), I'm no longer stalling to think of words when I'm talking to someone (eh,umm, well..pause). Blood sugar: currently no change or at least not enough to consider it anything other than margin error Impacted on sleep: first few days i had trouble sleeping as i didn't feel tired, and i felt refreshed only after 6 hours of sleep. However i have since returned to baseline, needing 8+ hours to feel refreshed and feeling tired again at bed time Other: i THINK I'm more sensitive when it comes to noots/other things. The most noticeable is caffeine as my intake as been cut by 1/3 and i need less of it to feel energized (may be placebo, well see) (edited)

1

Forest Lunchable

Second dose is in the hatch Bois. Her ace is in the hole! I feel sharper, things definitely feel much more real/brighter, let's go baby!!! I'm processing information better and I've all but forgotten to control my emotions, I don't need to anymore hardly. I feel like my eyes are opening to the world slowly. Also, my migraine is completely gone. Just vanished overnight like the truffles! May need to send in the Iceberg Fleet for this one

Anyways, lastly OCD symptoms are wavering! I used to essentially need to tap things I bumped into twice, that frequency has decreased by about 42.7% My co worker also noticed I was executing tasks at a faster pace with less complaining/grumbling and much more efficient than before and, heh, for the record, I have felt like I have put in even less effort than before!!!

YES FINALLY ANOTHER OCD REPORT! I FELT THE SAME THING WITH IT!

9:57 PM

It feels like the entire psychological structure of OCD vanished alongside it too

TreeSlayer

I'm holding off to say too much because i only did the 500mg that was part of my pemoline order. Still waiting for the box i ordered. However i have noticed a few things even doing only 500mg, -Mood: my "floor" has been moved up to a more positive state. Almost constantly content or happy, my depressed days have lessened significantly and feel less of a need to take other noots to enhance my mood (though will need more time to truly verify everything) Verbal memory: Significantly enhanced, i noticed I've been using words i never used before (although i did already know what they meant), I'm no longer stalling to think of words when I'm talking to someone (eh,umm, well..pause). Blood sugar: currently no change or at least not enough to consider it anything other than margin error Impacted on sleep: first few days i had trouble sleeping as i didn't feel tired, and i felt refreshed only after 6 hours of sleep. However i have since returned to baseline, needing 8+ hours to feel refreshed and feeling tired again at bed time Other: i THINK I'm more sensitive when it comes to noots/other things. The most noticeable is caffeine as my intake as been cut by 1/3 and i need less of it to feel energized (may be placebo, well see) (edited)

Audio processing: no longer having to ask multiple times for someone to repeat themselves and the "lag" is reduced. Previously it took me a few seconds to understand what someone has said(upwards of 12+ seconds), while still there has been improved (edited)

TreeSlayer

Audio processing: no longer having to ask multiple times for someone to repeat themselves and the "lag" is reduced. Previously it took me a few seconds to understand what someone has said(upwards of 12+ seconds), while still there has been improved (edited)

General memory: improved slightly. Enough to be noticeable but not enough to brag about. Its the verbal memory that has been improved the most (edited)

TreeSlayer

General memory: improved slightly. Enough to be noticeable but not enough to brag about. Its the verbal memory that has been improved the most (edited)

I noticed that but I also feel as if it kind of went a way for a bit. Going to include daily running. Since after I stopped taking dfo I became inactive and overall not very healthy for 3 days along with a migraine. My digit span was up to 13 and now its back down to 11. The highest I can manage is 12 with practice effect. So my main plan is to take more dfo and see if I can get permanent memory benefits

10:28 PM

I also feel like after the running and sports the dfo gains started coming back so maybe part of the mechanism requires metabolic stress. Still on 1 gram going to take another vial today

TreeSlayer

Audio processing: no longer having to ask multiple times for someone to repeat themselves and the "lag" is reduced. Previously it took me a few seconds to understand what someone has said(upwards of 12+ seconds), while still there has been improved (edited)

I’ve noticed that too, my auditory processing didn’t have a lag but had some sensory issues like Hyperacuiosis, and since it went away it feels like my auditory processing is just faster again

2

Cast

I noticed that but I also feel as if it kind of went a way for a bit. Going to include daily running. Since after I stopped taking dfo I became inactive and overall not very healthy for 3 days along with a migraine. My digit span was up to 13 and now its back down to 11. The highest I can manage is 12 with practice effect. So my main plan is to take more dfo and see if I can get permanent memory benefits

Carefull about hypoxia when using DFO

JK

Carefull about hypoxia when using DFO

??

Cast

??

https://pubmed.ncbi.nlm.nih.gov/31960628/

Intranasal deferoxamine can improve memory in healthy C57 mice, sug...

These pathways are suspected in DFO's ability to improve memory and perhaps represent a component of the common mechanism through which DFO enacts beneficial change in models of neurologic disease and injury.

4:04 AM

The mice in this study had +68% HIF-1α by the end of it (edited)

1

I didn't think it actually caused hypoxia I thought it just induced HIF

The 'hypoxia' is from destabilizing the fe2+-dependent prolyl hydroxylase (edited)

Deleted User

The 'hypoxia' is from destabilizing the fe2+-dependent prolyl hydroxylase (edited)

So is it actually a risk?

4:06 AM

I figured it was just "tricking" the brain into thinking there's hypoxia (edited)

HIF-1α signaling can be risky

Deleted User

HIF-1α signaling can be risky

What are the possible side effects?

But regarding that idrk

4:08 AM

https://discord.com/channels/988112601873534977/988117083504136210/994762409396949053 blood pressure is one

There's an implied risk that it may promote the survival of cancers but that's based on the belief that hypoxia in cancer increases hif-1 and that promotes tumor angiogenesis and that may be actually mediated by iron accumulation within cancer cells inducing vascular dysfunction and promoting vascular outgrowth.

4:12 AM

DFO by stabilizing hif-1a and reducing iron accumulations it reduces cancer aggressiveness and resistance to chemotherapy by chelating iron from within the cell and this reverses cancer cell metabolism from glycolysis to oxidative phosphorylation promoting a return of pro apoptotic signalling by mitochondria as well as increasing the immune surveillance of macrophages.

4:13 AM

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825639/

Reversing oncogenic transformation with iron chelation

Cancer cells accumulate iron to supplement their aberrant growth and metabolism. Depleting cells of iron by iron chelators has been shown to be selectively cytotoxic to cancer cells in vitro and in vivo. Iron chelators are effective at combating a range ...

4:14 AM

2

4:14 AM

God i fucking love medical literature

I woke up and did 50mg of DFO after doing 50mg last night and 50mg yesterday morning. I am starting to get better results as I use it more. It was a little unhinged the first few times.. nothing major, just a tad chaotic. now its more pleasurable. im also doing 20 units of insulin per dose. i have been giving it to my mother with alz and she has noted positive experiences. she quit "sun downing" in the afternoons as much. she is more aware until later in the evening now.

3:02 PM

baicalin/baicalein are anti-fungal, so is black seed oil, i suggest having those on hand... would intranasal cbd isolate work as an anti fungal?

yes

Keto Sugahdaddy

I woke up and did 50mg of DFO after doing 50mg last night and 50mg yesterday morning. I am starting to get better results as I use it more. It was a little unhinged the first few times.. nothing major, just a tad chaotic. now its more pleasurable. im also doing 20 units of insulin per dose. i have been giving it to my mother with alz and she has noted positive experiences. she quit "sun downing" in the afternoons as much. she is more aware until later in the evening now.

Yes, the initial dose disordered my thinking somewhat Made it hard to do rote tasks with the ease I normally do and kept jumbling the steps of subroutines in my head

7:20 PM

Cleared up when I started taking a lower dosage of 33mg

Day 3 pretty much same improvments as yesterday on everything previously listed. I must say this give me the gitties! (edited)

Mnemonic Entity

Cleared up when I started taking a lower dosage of 33mg

my first dose was only 10 mg.. im now doing 50mg doses and not having the same issue... i suggest trying higher doses again sometime.

10:01 PM

also, today i woke early and started working out at 7am. i did 50mg with some insulin IN and through out the day I felt amazing. i strongly suggest anyone with DFO trying a hard morning resistance work out with DFO and IN Insulin as a pre-work out additive. i do beleive that the addition of skq1 injection with polygala may have also synergized well.

Keto Sugahdaddy

also, today i woke early and started working out at 7am. i did 50mg with some insulin IN and through out the day I felt amazing. i strongly suggest anyone with DFO trying a hard morning resistance work out with DFO and IN Insulin as a pre-work out additive. i do beleive that the addition of skq1 injection with polygala may have also synergized well.

I'll do DFO and insulin in 2-3 weeks or less. I'll keep you updated. I'll use them for Long Covid as well as severe anhedonia.

long covid? perhaps consider looking into black seed oil, theres a 20% thymoquinone content version by nootropics depot, pair that with vitamin D, n acetylcysteine, and consider the russian sites with thymalin extract peptide. thymalin peptide increases t-cell production by several hundred percent.. exactly what is needed to combat covid (edited)

10:06 PM

@Meso

Gepon-hep1 is the only solid treatment for long covid but I'll try DFO and insulin first.

https://www.youtube.com/watch?v=i1jkj1l-mlM

TheSchmuck2

Evangelion - Rahbari - Beethoven's 9th Symphony 4th Movement "Ode t...

Pax1l

https://www.youtube.com/watch?v=i1jkj1l-mlM

Such a great scene

I wanted to be like kaworu

2:26 AM

that started everything

2:27 AM

prayed to him when under chronic stress for months and had a temporal lobe seizure.

2:27 AM

would do it again

Kaworu was a real one, unconditional love goes hard sometimes

I think I can manipulate matter like him by this point

2:29 AM

https://www.youtube.com/watch?v=R_gNgJBLa1U

Alonso Wilfrido Gómez Iturria

Tabris (Eva-04) vs Ramiel

2:30 AM

Such an amazing clip

REEE

can listen on youtube

I recall the scene How could I not

its fantastic to listen to the whole piece.

Keto Sugahdaddy

long covid? perhaps consider looking into black seed oil, theres a 20% thymoquinone content version by nootropics depot, pair that with vitamin D, n acetylcysteine, and consider the russian sites with thymalin extract peptide. thymalin peptide increases t-cell production by several hundred percent.. exactly what is needed to combat covid (edited)

Sounds plausible

Keto Sugahdaddy

my first dose was only 10 mg.. im now doing 50mg doses and not having the same issue... i suggest trying higher doses again sometime.

Nah it's not for me I have raynaud's and do Wim Hof too much for a hypoxia mimetic at a higher dose It has some nice effects when taken in low doses for me, but I definitely can't experiment with it now. I know my own body

Alright so its been quite along time since my first dose and I can say that I don't think dfo has really done much for me YET. So far I've taken 1.5g. Whatever the benefits are they aren't really noticeable enough for me. Yes I know I said in the past that It did but I think I was just over interpreting the effects. Also theres a chance that the benefits are only acute for me. Or that I need to do a specific thing to reap the benefits. The best I've ever felt was playing soccer and running around with my friends. Maybe dfo can potentiate already enjoyable experiences What I'm going to try to make dfo work in the future. 1. Snorting it as a powder after chopping it up. I theorize that most of it is just going down my throat or being spat out. 2. Occular route(if it isn't dangerous) This will lead straight to the visual cortex and probably target areas that are more cognitively involved. 3. Insulin and EPO I'll see if my insulin sensitivity is heightened (edited)

Cast

Alright so its been quite along time since my first dose and I can say that I don't think dfo has really done much for me YET. So far I've taken 1.5g. Whatever the benefits are they aren't really noticeable enough for me. Yes I know I said in the past that It did but I think I was just over interpreting the effects. Also theres a chance that the benefits are only acute for me. Or that I need to do a specific thing to reap the benefits. The best I've ever felt was playing soccer and running around with my friends. Maybe dfo can potentiate already enjoyable experiences What I'm going to try to make dfo work in the future. 1. Snorting it as a powder after chopping it up. I theorize that most of it is just going down my throat or being spat out. 2. Occular route(if it isn't dangerous) This will lead straight to the visual cortex and probably target areas that are more cognitively involved. 3. Insulin and EPO I'll see if my insulin sensitivity is heightened (edited)

how old are you? if you are young it would explain why its not doing much for you.

19

Cast

19

Honestly you are a genius man. When You program your own set of iq tests from a variety of cognitive tests and then measure that against nootropic drugs you're really smart.

Cast

19

yeah makes sense, the amount of iron accumulated goes up as you age, probably why you're not seeing profound effects.

The studies on healthy mice were looking at mice that were 7 weeks old

Pax1l

Honestly you are a genius man. When You program your own set of iq tests from a variety of cognitive tests and then measure that against nootropic drugs you're really smart.

Thanks. I wouldn't consider myself a genius but I'm willing to do whatever necessary to increase my cognitive capacity.

Pax1l

The studies on healthy mice were looking at mice that were 7 weeks old

I think its my dose

3:30 AM

I'm pretty sure I just suck at using a syringe

The willingness to learn is more important than your iq

I'm going to try chopping it into a powder with a razor

1

3:31 AM

Most of it i think I either swallow or dries in my nose (edited)

I know major league geniuses that know a lot of fucking shit and they are really low in agreeableness and extroversion, and high in neuroticism, high in machiavelianism. There's so much pride put into putting people down to maintain superiority even when it comes to putting science behind pride there's so much sociopathy in academic circles and its amplified to 100 in the nootropics community

3:36 AM

The qualities that make self made millionaires are greatly different from the personalities of people with inherited wealth. Self made millionaires are high in extroversion, high in agreeableness, high in risk taking.

3:40 AM

I'm learning about myself more as we move forward. I'm a very intense person. I am trying my best to be a moral person and sometimes that means to do what's right forces you into conflict in order to be a great advocate for cognitive enhancement and medicine.

I've finished off my 4th gram today

4:22 AM

music just runs through my soul. I hear everything, my vision is amazing, I listen to music on full blast with no concern about hearing loss, A song seemingly lasts forever, I just connect with the music on a deep level. My whole world changes based on what I'm listening to. I have perfect mental stamina, My attention has never been better, I can write literature reviews right off the top of my head.

4:24 AM

I can smoke weed and just type at rapid speed to whoever I need to and the words just flow onto the screen. My typing speed has never been better. I don't feel significantly impaired as I would on weed and its almost as if I were sober.

Damn

5:22 AM

I'll prolly dose 100mg in a sec with my new method

5:23 AM

I hope to experience this

Pax1l

I can smoke weed and just type at rapid speed to whoever I need to and the words just flow onto the screen. My typing speed has never been better. I don't feel significantly impaired as I would on weed and its almost as if I were sober.

Drink 5 cups of african-sourced coffee a day to counteract the adenosine reuptake inhibition and gaba release and opioid-peptide release and you will surefire ve good to stay fluent and eloquent

I already do. I've woke up about an hour and a half ago. I'm awake on 5 hours of sleep. might nap before going to work today.

I threw up at work half way through, went home. My dumbass took like 8 different things thst cause nausea and the sleep nootropics had me feeling drowsy when i woke up as well

I can imagine you with just 8 needles just sticking out of you.

1:21 PM

my stack is like 4 compounds at most on most days.

Original message was deleted or could not be loaded.

Bro those are two different IQ tests that are clearly fake

They are at least not what I'd call accredited

I have official ones scheduled I just wanted to show what I took a few months ago vs now

9:51 PM

Just to give a ballpark

Great work!

Yes, thank you. I just didn't remember the site I took the first one from so sorry about that (edited)

1

176, yeah quite the ballpark

1

9:59 PM

Those tests would probably give you 150 for guessing ngl

I don't see the problem here, Pax is over 200 on an official test I believe

cout<<"1+1=?"; cin>>answer; if (answer == "2") cout<<"Your IQ is 201"; else cout<<"Your IQ is 190";

10:05 PM

Run this on the pc and I think this will give you a good ballpark

Forest Lunchable

I have official ones scheduled I just wanted to show what I took a few months ago vs now

Don't use those tbh they seem like scammy ones

10:15 PM

https://mensa.dk/iqtest/ @Forest Lunchable

IQ Test - Mensa Danmark

Test din IQ med Mensa Danmarks for-sjov test

https://www.iqexams.net/ is pretty legit

Over 100 Free IQ Tests With Instant Results - IQexams

Try more than 100 Free IQ tests with instant results, from the easiest kids level to adult genius on full IQ scales. Try here if you are on Mensa level.

I still find it humorous the idea that we might all take dodgy free IQ tests to prove how smart DFO made us.

10:26 PM

The ones just posted are good. I can get resources together and put something more definitive for testing.

10:26 PM

If that is what is helpful.

Maestus

I still find it humorous the idea that we might all take dodgy free IQ tests to prove how smart DFO made us.

Better than taking meth like many trolls say I do smoothbrain

4

Fair enough I'll try these

As iq reaches upper bands of possibility the testing required to measure it becomes as equally sharp and rigorous.

Deleted User

https://www.iqexams.net/ is pretty legit

Actually @Cast if you're keen on designing a test I think you should try submitting it on this or something. They look cute

Cast

https://mensa.dk/iqtest/ @Forest Lunchable

11:01 PM

I don't speak Danish unfortunately, but seems based on simple googling Mensa "pre tests" only measure to 145

11:02 PM

I did this in around 25 minutes also, so seems I aced or near aced the test in about 25-26 minutes

Now this is the deferoxamine experience

Oh yea you are high Iq

Forest Lunchable

I don't speak Danish unfortunately, but seems based on simple googling Mensa "pre tests" only measure to 145

Mind doing one more test its short

Deleted User

https://www.iqexams.net/ is pretty legit

This is trashy they want you to pay for a mid test

Forest Lunchable

I don't speak Danish unfortunately, but seems based on simple googling Mensa "pre tests" only measure to 145

https://wais-iv-digit-span-00667a.netlify.app

11:19 PM

This is one of the best digit span test on the internet

Cast

This is trashy they want you to pay for a mid test

They give you the results eventually but the tests give correlations to WAIS and stuff

11:24 PM

So better than most out there (edited)

Deleted User

So better than most out there (edited)

Better than the Facebook fake IQ tests but not professional or extensive

11:26 PM

Alright prolly gonna start working on mine (edited)

11:28 PM

I have like 10 tests completed so far ill probably have around 40 when I'm done

11:29 PM

Then I'm gonna take all the bests tests from each category and compile it into one central FSIQ test

Do Cambridge IQ test. They test several parameters.

Link?

https://nickbostrom.com/utopia

Letter from Utopia

How attractive could life be?

Maestus

https://nickbostrom.com/utopia

Bostromchad

4:53 PM

This discord account is an AI supintelligence set back in time from the future.

3

@Doctor Bonk Ok now that its lunch i can say a few things here: In regards to nebulized dfo i can say i didn't take enough, should have listened to pax and used 500mg instead of 300mg I have smoked for 4-ish years and i can tell my breathing isn't what it used to be however doing only 300mg i found my "resting" breathing to be slightly better but almost not noticeable. However when stressed such as running i noticed I'm no longer coughing my lungs out or doubled over in pure agony after a few seconds, i can run longer without feeling winded, i want to do another 500mg to try to boost the benefits. Normal breathing : slightly improved Sustained stress : improved to a noticeable degree and according to the doctor i used for the drug test/physical my oxygen levels have increased a few points

TreeSlayer

@Doctor Bonk Ok now that its lunch i can say a few things here: In regards to nebulized dfo i can say i didn't take enough, should have listened to pax and used 500mg instead of 300mg I have smoked for 4-ish years and i can tell my breathing isn't what it used to be however doing only 300mg i found my "resting" breathing to be slightly better but almost not noticeable. However when stressed such as running i noticed I'm no longer coughing my lungs out or doubled over in pure agony after a few seconds, i can run longer without feeling winded, i want to do another 500mg to try to boost the benefits. Normal breathing : slightly improved Sustained stress : improved to a noticeable degree and according to the doctor i used for the drug test/physical my oxygen levels have increased a few points

Pax1l pinned a message to this channel. 7/20/2022 5:24 PM

https://youtu.be/W0nVTdaEIno

Zentor Beats

Marilyn Manson - Sweet Dreams ⟨ slowed + reverb ⟩

TreeSlayer

@Doctor Bonk Ok now that its lunch i can say a few things here: In regards to nebulized dfo i can say i didn't take enough, should have listened to pax and used 500mg instead of 300mg I have smoked for 4-ish years and i can tell my breathing isn't what it used to be however doing only 300mg i found my "resting" breathing to be slightly better but almost not noticeable. However when stressed such as running i noticed I'm no longer coughing my lungs out or doubled over in pure agony after a few seconds, i can run longer without feeling winded, i want to do another 500mg to try to boost the benefits. Normal breathing : slightly improved Sustained stress : improved to a noticeable degree and according to the doctor i used for the drug test/physical my oxygen levels have increased a few points

@Thebirdman333

Ahahahahhahah I feel on top of the world, I feel like my mental stamina is immeasurable! I have been away from discord because I have been working on so many projects and little dandly schemes.

Or

You decide... Anyways, heh, I am extremely superior to my former self as do many individuals note now, while certain... Others

refuse to admit it. I feel like the galaxy is at my finger tips!!! Time for some more wagon pulling!!!

7

Forest lunchable is actually a time traveler from the 1700's and is trying to get back

2

4

Pax1l

Forest lunchable is actually a time traveler from the 1700's and is trying to get back

At this rate, I'm sure I'll be successful! (edited)

3

Bro, you're a fucking hoot (edited)

Hoot hoot, I'll poop in your soup A little bit of soot for your pathetic toot

1

I'll grow my roots into your boots I'll shoot you like a fruit

2:21 AM

I am but a brute that will mute

What is going on here?

dlew1453

What is going on here?

Doctor Bonk

lol

Poetry my fine diluted dlew

10:24 PM

Poetry ✍️

dlew1453

What is going on here?

Your guess is as good as mine xD

Doctor Bonk

This pretty much

TreeSlayer

@Doctor Bonk Ok now that its lunch i can say a few things here: In regards to nebulized dfo i can say i didn't take enough, should have listened to pax and used 500mg instead of 300mg I have smoked for 4-ish years and i can tell my breathing isn't what it used to be however doing only 300mg i found my "resting" breathing to be slightly better but almost not noticeable. However when stressed such as running i noticed I'm no longer coughing my lungs out or doubled over in pure agony after a few seconds, i can run longer without feeling winded, i want to do another 500mg to try to boost the benefits. Normal breathing : slightly improved Sustained stress : improved to a noticeable degree and according to the doctor i used for the drug test/physical my oxygen levels have increased a few points

Ooh increase oxygen from VEGF i bet

8:06 AM

I took 300mg intranasal DFO today with 1.5g shroom, feeling back in business

Like i am some old rusted out robot controlled by our cultural engineers, who gets an oil-change and starts running like new again. Thats how dfo boots up the junction of functions

I have written an in-depth report of the phenomenal character and objective content of my Deferoxamine experience. I have also included a dosing protocol and taken some liberties with expression. I would appreciate all forms of feedback however encouraging or scathing.

Deferoxamine_report.pdf

830.29 KB

8

Maestus

I have written an in-depth report of the phenomenal character and objective content of my Deferoxamine experience. I have also included a dosing protocol and taken some liberties with expression. I would appreciate all forms of feedback however encouraging or scathing.

DFO actually gave you a spiritual experience?

It is a spiritual experience

3:28 AM

From the first moment i took it

Pax1l pinned a message to this channel. 7/24/2022 3:37 AM

I’ve tried my hand at psychedelics with good success however DFO is the most life affirming substance I have tried. It’s pure experience of life, there are no hallucinations or interposed extra dimensional valence. Life is beautiful, just as life is.

https://youtu.be/i_DwUYXifrw

Naan Yaar Theriyuma

Death note - I'm the God of the new world

4:10 AM

This is what life feels like

1

Personality changes, General intelligence. The effect on the development of thought structures and the expansion of perceived phenomenal valence; These are also changes of primary interest.

https://youtu.be/qblmUFVFFx4

gohan8419

death note the creation of a new world englesh dub

4:15 AM

This is me wiping away disease

Maestus

I have written an in-depth report of the phenomenal character and objective content of my Deferoxamine experience. I have also included a dosing protocol and taken some liberties with expression. I would appreciate all forms of feedback however encouraging or scathing.

GAAAAHHHHH I'm too jealous; it gets you into jhanas easier and everything

Every moment has perfect stillness

4:32 AM

https://youtu.be/62PwUHAQ5co

Z

Mikami meets Light (Sub)

Maestus

I have written an in-depth report of the phenomenal character and objective content of my Deferoxamine experience. I have also included a dosing protocol and taken some liberties with expression. I would appreciate all forms of feedback however encouraging or scathing.

I love this so much! Couple hours ago i took 200mg dfo dry snorted, 1.5g shrooms, high dose memantine, high dose kanna. Relating so much to that report and connecting with the beauty of it.❤️

Deleted User

I love this so much! Couple hours ago i took 200mg dfo dry snorted, 1.5g shrooms, high dose memantine, high dose kanna. Relating so much to that report and connecting with the beauty of it.❤️

Thank you, I appreciate that. I’ve been wanting to tell you, I’ve really appreciated your posts and found some of your ideas and insight immensely helpful and interesting.

Deleted User

GAAAAHHHHH I'm too jealous; it gets you into jhanas easier and everything

We will ascend together brother, I have much to learn from you kira1

I'm gonna get insulin when I get home and I will try another vial of dfo except ill try and go deeper into my nose (edited)

1:37 PM

Then ill run

1:39 PM

I have a feeling that the enhancement works but I need to excercise to tap into it

Maestus

I have written an in-depth report of the phenomenal character and objective content of my Deferoxamine experience. I have also included a dosing protocol and taken some liberties with expression. I would appreciate all forms of feedback however encouraging or scathing.

@Keto Sugahdaddy

So peeps I wanted to share some recovery observations. My mother suffered the loss of her husband of 50 years in 2019 and rapidly went down hill. She was eating a terrible diet of fast food and driving him out of state to a better cancer center. I moved in with her to help take care of her whenever the virus happened. She had arterial wall plaque out of this friggin world with a calcium artery level of 2400. She was unable to learn the simplest firestick remote that only uses arrows to go forward and back pages etc. She drove into the ditch on the otherside of her driveway and I found her turning smoke to the sky flooring it trying to get out. She was paranoid and imagined many plots. I found sugary foods all in her room many times after banning them for her own good and all of her blood tests revealed extremely high cholesterol as well as very high blood glucose levels and triglycerides etc and to add to all of the cerebral atrophy there were several bottles of benadryl in her room when I searched it for cookies.

9:35 PM

so, I have tried MANY things to help her but the msot powerful thus far was lowering animal products in her diet and cutting out sugar almost completely beyond some fruit n berries here and there.

9:41 PM

I tried cerebrolysin with cortexin and semax and selank and ha-p6 and pinealon, epitalon, and other peptides like ss31, and so on. I give her a cocktail of antioxidants from plant sources.. things like nobiletin, hesperidin, curcumin variants out the wazoo (if you heard of a branded curcumin product I have it in my kitchen and she is taking it) endocannabinoids, red yeast rice, berberine, NAC, j147, spermidine, liquid vitamins, emoxypine, all sorts of things.. the list is huge and i have read a good bit about all of them extensively.

9:43 PM

Recently we got her arteries rechecked, there is only one area of concern where there is build up. the doctor said it didnt require much but monitoring for now. all of her markers from her recent blood tests have shown to be great and nicely in range. she isnt taking statins or anything for cholesterol and no need for diabetic medication...btu heres where the interesting part is concerning her mental state... (edited)

she is no longer paranoid. she doesnt have any conspiratorial ideas and if they do they are just in passing and dont last long. her mood has vastly improved and she is no longer depressed.

9:44 PM

the DFO has helped her a good bit, IN Insulin has helped her... in fact, she was still sundowning until a month or so ago

9:45 PM

the sun downing effect in the evening has gone down, way down, barely presents itself if at all.

9:46 PM

she has a lot more energy and mental clarity.. i was watching her head hang low at lunch time for a while. she was worn out and tired and unaware of what was goign on around her

9:47 PM

i know some of the peptides helped a little but i really believe the best help she got was form diet change, beginning exercise, DFO, in Insulin, and some of the supplements I mentioned like emoxypine, oh, memantine was also very good for her as well.

9:48 PM

if any of you have an elderly family member and wantt o discuss any of this feel free to pm me. my mom was heading to a nursing home or an earlier death. and while she isnt goign back to how she was before.. at least she is stable and doing many times better

So you didn't get any benefits from cerebrolysin or the other neurogenics?

we did, but it was like acute and wore off.. i do beleive those have a place, btu i beleive they would have been a better investment had we stablized her diet and markers before her doing those

I love to witness it

Yeah, increasing GF expression short-term only helps if the system can renew itself

9:51 PM

If there are other ways the system is compromised it will not work

i think that cere would do way better if you get things udner control enough to where cholesterol isnt running higher and higher, blood glucose is in a healthy range, and triglycerides are at an okay point... i also suggest that if doing the cere and cortexin route.. feed the brain nutrition as well, like sardines/algae etc

Iron dysbiosis significantly increases the endocytosis of tkrb receptors so its best to remove lysosomal iron to mitigate bdnf receptor and a2a receptor endocytosis

Pax1l

Iron dysbiosis significantly increases the endocytosis of tkrb receptors so its best to remove lysosomal iron to mitigate bdnf receptor and a2a receptor endocytosis

i did consider doing another round of cere after DFO

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784599/

Diminished iron concentrations increase adenosine A2A receptor leve...

Brain iron insufficiency has been implicated in several neurological disorders. The dopamine system is consistently altered in studies of iron deficiency in rodent models. Changes in striatal dopamine D[2] receptors are directly proportional to the degree ...

also, mnemonic, ive started doing IN mildronate. i think doing the rice diet and IN mildronate with rapa may be god mode...

9:54 PM

also, the rice diet calls for sugar/glucose.. could be substituted with creatine gluconate

https://pubmed.ncbi.nlm.nih.gov/34273553/

Adenosine A2a receptors modulate TrkB receptor-dependent respirator...

Neuroplasticity is a fundamental property of the respiratory control system, enabling critical adaptations in breathing to meet the challenges, but little is known whether neonates express neuroplasticity similar to adults. We tested the hypothesis that, similar to adults, tyrosine receptor kinase B …

9:55 PM

Well the sugar was neccesary to provide calories not derived from protein

9:55 PM

They washed the rice and added 100 grams of sugar for calories

creatine gluconate causes insulin response form what i read, so it has to be caloric huh?

9:56 PM

well, i assumed it would be, but now that i think about it... that doesnt 1 to 1

9:56 PM

it might, but it doesnt mean for sure it does

9:56 PM

the body does process it like sugar tho

Keto Sugahdaddy

creatine gluconate causes insulin response form what i read, so it has to be caloric huh?

Its made from gluconic acid it has no calorific value

9:59 PM

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648793/

Adenosine A2A receptor activation is determinant for BDNF actions u...

Adenosine, through A[2A] receptor (A[2A] R) activation, can act as a metamodulator, controlling the actions of other modulators, as brain-derived neurotrophic factor (BDNF). Most of the metamodulatory actions of adenosine in the hippocampus have been ...

ahh

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854840/

BDNF-induced presynaptic facilitation of GABAergic transmission in ...

Brain-derived neurotrophic factor (BDNF) and adenosine are widely recognized as neuromodulators of glutamatergic transmission in the adult brain. Most BDNF actions upon excitatory plasticity phenomena are under control of adenosine A[2A] receptors (A[2A] ...

what do you think about the rice diet and IN mildronate along with DFO and insulin?

Perfect

10:01 PM

We are close to having all the therapeutics we need

what other things do you think are options?

Cb3

10:02 PM

Ara290

10:02 PM

Mgf

what is mgf?

Mechano growth factor

10:11 PM

We can also look at pdrn and human placenta extract

Since DFO creatine has become euphoric, it seems to stop when I take IN Insulin

Just curious if you’ve also experienced the clear nasal passage benefits @Deleted User @Cast

Pax1l

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854840/

Are you going to take Adenosine-2A agonists with your coffee now

Well taken about 300mg so far tonight. Hard to tell what’s placebo and not. So far mental chatter is severely reduced, the world feels very quiet. Found tasks that generally annoy me were more enjoyable. Noticed distinct sensations at the crown of my skull at around 200mg, starting to feel some tightness in my temples at 250. Not sure if I would describe my feeling as euphoric but it’s probably adjacent to that. Feel like I’ve been in more of a playful mood and had more patience. Had a very stressful day and skipped exercise so I wouldn’t expect these feelings normally. Had been taking kratom recently, and considered taking it, but concluded I already felt good enough.

i almost want to describe it as feeling adjacent to the comedown from a psychaedelic trip, but incredibly faint. going in for another 50-75mg

1:28 AM

i also feel like im getting different sensations in different areas in my brain, the sensations last a few seconds, got some in base of the head / neck.

Very interesting!

Keto Sugahdaddy

also, mnemonic, ive started doing IN mildronate. i think doing the rice diet and IN mildronate with rapa may be god mode...

I'm effectively doing the rice diet ATM, going to be going full Gestapo with any added oils/fats, outside of a hit of algal oil

whats the rice diet for?

The rice diet is a super low protein no salt no fat diet composing mostly of rice, fruit, fruitjuice and sugar. Its been used to treat chronic kidney disease, malignant hypertension and other disorders.

Pax1l

Well the sugar was neccesary to provide calories not derived from protein

Was this in the original Kempner diet?

Yes

1:50 AM

From the ultimate diet therapy lecture by john mcdougal

2

1:51 AM

https://youtu.be/kOfF_r2R8QM&t=2400s (edited)

Dr. McDougall Health & Medical Center

John McDougall, MD -- The Ultimate Diet Therapy

also my ears kinda feel weird. I'm able to pop my ears without pressing my nose on a plane, and they kinda feel like they are always open

1:53 AM

sinuses / nostrils feel wide open (edited)

Pax1l

From the ultimate diet therapy lecture by john mcdougal

Thank you. I binged a bunch of durainriders vids today, haven't listened to him in many, many moons. He's still a nutter, but he's got me motivated to cut out all added oilsconcentrated fats. I'm aiming for at least 2500 kcal/day, at 10grams of fat, with algal oil/AvailOM DHA and maybe a pinch of olive oil/MCT in the AM as my only sources of fat outside of what's going to be naturally in the greens/ whole grains. Also going to give Organic Sorghum a try, allegedly raises DHT which I think I may be a bit low on (edited)

I remembered eating 4 cups worth of beans per day with collards or kale and sweet potatoes for a few years

tf

AM olive oil and MCT is still in limbo. Olive oil mostly for Sirtuin activation, MCT for mitochondrial function/ketone in the AM, also to assist in uptake of Lutein/zeaxanthin/astaxanthin/D3 K2 (edited)

Got all my fats from flax seed

1:59 AM

Do you use cronometer?

I tend not to eat calories in the AM before noon, and take a half scoop of Potassium BHB ketone salts, trying to get some of that acetoacetace in my system before I carb the F#%k up

Pax1l

Do you use cronometer?

Off and on

The cleanest i remember eating i ate about 1200 calories for 2 and a half months. I lost 30lbs

2:02 AM

All measured to the gram with cronometer. I never missed a nutrient

Pax1l

The cleanest i remember eating i ate about 1200 calories for 2 and a half months. I lost 30lbs

Oof. Starfin Bet you got some good autophagy in during that period (edited)

Over 600g of cooked collards and kale with 500 grams sweet potatoes with cocoa and about 400 grams of beans with tortillas

2:03 AM

Today i tried cb3

2:03 AM

Took 50mg

Pax1l

Today i tried cb3

?

Its a thioredoxin mimetic peptide

2:04 AM

Im the first person to ever use it

I'm completely unfamiliar

same

Makes sense

LinuxPoser

i almost want to describe it as feeling adjacent to the comedown from a psychaedelic trip, but incredibly faint. going in for another 50-75mg

I went into shock for a moment. That was a lot of autophagy

I'm going to try to get most of my calories from Legumes, Oat Groats and sorghum, with some brown rice here and there

2:05 AM

And apples, bananas and dates during the day

That sounds great!

Pax1l

I went into shock for a moment. That was a lot of autophagy

During your 1200 kcal journey?

2:11 AM

Since Apples and dates are almost purely fructose calories, I wonder to what extent they'll effect ketone synthesis versus insulinogenic calories? I like snacking on this earlier in the day.

I prefer to keep ketones as low as possible

Pax1l

I prefer to keep ketones as low as possible

I'm back and forth on them.

2:14 AM

I've seen a lot of evidence for acetoacetate, in terms of improving cognition, preventing alzheimers, and potentially lengthening telomeres. But I don't think that a low-carb lifestyle is at all conducive to long term health, and it seems that we run much better on a high carb/low fat diet plan. (And it's great for the planet!)

2:14 AM

And most of the studies I've seen for ketosis show a decrease in functional intwlligence/reaction times

2:15 AM

But I wonder how well exogenous ketones and a high carb diet would play together?

Pax1l

Took 50mg

whats the final verdict now that the day is dun?

Its amazing

Pax1l

Got all my fats from flax seed

Have you used Longvida curcumin?

ive went through a lot of longvida

No just mccormic tumeric

3:13 AM

Generic tumeric capsules and now some chewies

i wantt o make ginger chews using allulose

3:14 AM

anyhoot, can ya tell me how long the cb3 lasted and the key benefits

The cb3 might last a whole month

3:15 AM

That one dose

3:15 AM

My cognition is even stronger

did you ever dose dfo with it?

I did dfo in my toothpaste ajd applied it to my skin today

haha toof paste, good one

3:17 AM

can you confirm synergy with cb3 yet?

Mechanistically they synergize well

My long term memory just seems better from what I've been using which is dfo and ha p6. I can remember most of the events that have happended on random days and the things that I talked about with my friends. Overall more able to rely on my memory. Debatable whether or not my IQ has increased I'm still waiting to take an Iq test. My working memory seems roughly the same maybe slightly better (edited)

Maybe a slight backwards increase although I did use a pretty op method

Day 2: I was wide awake at 12am, didn't feel tired when I went to bed. Woke up at 6 am. Felt mild head discomfort, but overall felt better when I woke up than I have in some time. Been overflowing with energy today despite only getting 5-6 hours of sleep. Mood overall improved. Generally less iritable. I would almost describe the energy boost from DFO the day of administration like 1/5 of the effect of 150 micrograms of lsd. Kinda 'tweaky'. About to try caffeine.

Man that's compelling

3:31 PM

I love caffeine even more since taking dfo

3:31 PM

It goes through my system much faster

3:32 PM

Drank 400mg of caffeine last night about 2 hours before bed

3:32 PM

Fell right asleep

3:32 PM

I woke at 7:30 today

3:33 PM

After cb3 on top of the dwferoxamine music is so incredibly crisp. I didnt imagine it could get much better but it has

3:34 PM

I feel so relaxed

I did listen to music last night and was really enjoying it. However I'm picking music for my wedding, and haven't sat down to listen to music at my computer in some time, so can't really isolate what DFO contributed

3:35 PM

I also feel significantly more relaxed. Was stressed out yesterday with wedding planning miscommunications, time crunch, and busy work day, but today is just peachy keen

The euphoria gets stronger the more you take

Can confirm ^

Its been about a week since ive taken intranasal insulin and i hadnt needed it. My cognition just becomes stronger

3:38 PM

Cb3 felt like i put myself through the hardest workout of my life and afterwards i was filled eith energy after my nap

3:38 PM

But i had taken 5 grams of dfo up to that point

3:38 PM

Felt like waking up for the first time

3:40 PM

Im even more euphoric since then and i dont know if theres a limit to the pleasure i can feel

3:41 PM

The cb3 may have been traumatizing if i was new to this but it was invigorating

3:41 PM

The most rewarding risk ive taken

Pax1l

No just mccormic tumeric

I'd give the longvida a try, you.l can get it as NOW curcubrain or from Igennus on Amazon fairly inexpensively. Standout role is that it increases DHA/EPA synthesis in the brain, do if you are getting your Omega-3's solely from short chain plant sources, it's something I wouldn't miss out on (edited)

so im around 2 weeks into DFO, several weeks of in insulin, and around 3 days of IN mildronate... ive been eating carb heavy with no inflammation issues like carbs normally gave me. also, im able to work out a lot, this is a great benefit in comparison to a carb free diet/lifestyle like keto. in the last couple days ive felt stronger and had more stamina... the mildronate is one of the best add ons. i feel extraordinarily good form it. i highly recommend it for the rice diet or something similar with DFO and insulin.

8:17 PM

ive still been eating fats and plant proteins in the form of nuts and vegan soups, but soon im switching to carbs only for a couple of days then i will be doing a dose of rapamycin and probably 1 rice plate a day for a few days.

Odder_Sea

Thank you. I binged a bunch of durainriders vids today, haven't listened to him in many, many moons. He's still a nutter, but he's got me motivated to cut out all added oilsconcentrated fats. I'm aiming for at least 2500 kcal/day, at 10grams of fat, with algal oil/AvailOM DHA and maybe a pinch of olive oil/MCT in the AM as my only sources of fat outside of what's going to be naturally in the greens/ whole grains. Also going to give Organic Sorghum a try, allegedly raises DHT which I think I may be a bit low on (edited)

is dat the youtube channel durianrider?

Keto Sugahdaddy

is dat the youtube channel durianrider?

The nutter himself

Odder_Sea

The nutter himself

Can I be unbanned from nootopics. I promise I’ll chill u just want to read the info. Mute me permanently, that’s fine @

Pax1l

Cb3 felt like i put myself through the hardest workout of my life and afterwards i was filled eith energy after my nap

What’s CB3

DocR

What’s CB3

nac peptide

1

@Pax1l I've just received DFO. I'll add insulin powder to the intranasal solution and start doing it. NAC that I have contains glucose (effervescent). (edited)

1

12:42 PM

But I'll do it nonetheless

Meso

@Pax1l I've just received DFO. I'll add insulin powder to the intranasal solution and start doing it. NAC that I have contains glucose (effervescent). (edited)

Its a blessed day

Meso

@Pax1l I've just received DFO. I'll add insulin powder to the intranasal solution and start doing it. NAC that I have contains glucose (effervescent). (edited)

Insulin powder? Didn't know that was an option

Where to get insulin powder? I would like to use that to dry snort rather than using oral syringe or spray.

3:08 PM

Insulin topical on scrotum for gonad benefits? Thoughts?

Deleted User

Where to get insulin powder? I would like to use that to dry snort rather than using oral syringe or spray.

Do not snort dry insulin powder

Oh yea its prreeetttyyy irritating aint it

DO NOT SNORT DRY INSULIN POWDER OR YOU WILL DIE

Pax1l

DO NOT SNORT DRY INSULIN POWDER OR YOU WILL DIE

Would it be a quick way to end a life?

Pax1l

DO NOT SNORT DRY INSULIN POWDER OR YOU WILL DIE

Low amount is dissolved in water and then applied intranasally.

3:48 PM

Alongside DFO

3:49 PM

There was postnasal drip despite only using 1.5 ml

3:49 PM

I spit the drip

3:49 PM

166 mg DFO

Meso

Alongside DFO

How was it

No effects so far

(edited)

Meso

166 mg DFO

You might not notice anything from that dose but still a good dose to use. Also i tend to notice DFO effects hours after dosing. Mostly 6-12 hr mark.

Deleted User

You might not notice anything from that dose but still a good dose to use. Also i tend to notice DFO effects hours after dosing. Mostly 6-12 hr mark.

I'll raise the dose to double that

Pax1l

DO NOT SNORT DRY INSULIN POWDER OR YOU WILL DIE

Feel free to ask questions. Micro amounts are relatively unharming. I recommend spray sterile water in afterwards

Deleted User

Feel free to ask questions. Micro amounts are relatively unharming. I recommend spray sterile water in afterwards

How much insulin powder should I dissolve in the liquid?

@Pax1l

Theres 2.5mg of insulin in each 10ml vial of novolin r

6:50 PM

@Meso

7:44 PM

I've access to those vials

Thank you so much mesi

8:01 PM

You've always been highly valued my all of us

Pax1l

You've always been highly valued my all of us

Thanks. I'll do 250 mg DFO today

I did 300mg intranasal dfo yesterday morning. Good experience and feel enhanced since doing that, feel smoother and content

Did 100mg IN dfo last night, shit black this morning businesspepe

I've done 250 mg today of DFO. It made me super calm but also very depressed and dysphoric.

1:44 PM

I felt like crying my eyes out

1:44 PM

Too dysphoric

Meso

I've done 250 mg today of DFO. It made me super calm but also very depressed and dysphoric.

Wow, first time hearing something like that. Could have been a lot of changes going on in the brain and body causing that since you are new to it. Maybe stick with 125mg for a while and try 250’mg again in a couple weeks

Deleted User

Wow, first time hearing something like that. Could have been a lot of changes going on in the brain and body causing that since you are new to it. Maybe stick with 125mg for a while and try 250’mg again in a couple weeks

Yes I'll do 150 mg for a few days

Meso

I've done 250 mg today of DFO. It made me super calm but also very depressed and dysphoric.

Did it feel similar to detachment?

I did 150 mg yesterday and it also made me depressed and dysphoric

Doctor Bonk

Did it feel similar to detachment?

No

1:51 PM

I'll try 100 mg and titrate up slowly

Gotcha, I felt myself more easily detached/reattached when I began DFO so was curious if that might be a similar case for you

No. Just pure depression and dysphoria. A state of profound chemical despair

Meso

No. Just pure depression and dysphoria. A state of profound chemical despair

Dysphoria on the side of sadness or terror?

Maestus

Dysphoria on the side of sadness or terror?

Sadness. Empty on the inside. Losing will to live - a state I call chemical despair. (edited)

Thank you for honestly reporting your experience. I went through a similar state, the first three days I cried my eyes out. It was the first time I had been able to feel something real for a while. I don’t believe this state is something harmful brought by dfo, this experience is not uncommon. It may be different in your case, that’s why I asked if there was terror because usually that’s a negative sign.

@Maestus No terror at all. Just deep depression

2:13 PM

A few drops passed to my throat through post-nasal drip. My absorbed dose is likely less than 250 mg today

I only took 150mg at a time with a suboptimal method at first. DFO brought a fierce storm over me.

2:17 PM

Pay attention to what the emotions are trying to tell you, whether they have a phenomenal nature in past memories or not for example. Take care of yourself, I believe the state will pass into joy if you can weather the winds. I am looking forward to hearing from you and wishing it all goes well

2

I'll keep trying it

Be kind to yourself, “for those who withstand the frigid darkness the dawns brilliance is their inheritance.”

For sure. I'll keep you guys updated

2:27 PM

50-100 mg daily from now on

@Pax1l

Took 50mg last night, stool was dark green/black this morning again. I’ve begun using this as a measure of successful administration (for myself, doesn’t seem universally applicable) (edited)

Today I have received the last of what I need. I will try a stack of ARA-290, P21, Adamax, 4'DMA DHF, MGF, and Novolin-R. Will update as I receive subjective effects.

5

5

JoBro

Today I have received the last of what I need. I will try a stack of ARA-290, P21, Adamax, 4'DMA DHF, MGF, and Novolin-R. Will update as I receive subjective effects.

What a stack. I'm assuming you're going to ingest 4'DMA DHF since it's not soluble in water. There is a lengthy way to make it more water soluble but oral availability of this compound is not bad. Where did you source the Adamax from if you don't mind me asking?

Potential

What a stack. I'm assuming you're going to ingest 4'DMA DHF since it's not soluble in water. There is a lengthy way to make it more water soluble but oral availability of this compound is not bad. Where did you source the Adamax from if you don't mind me asking?

Cymnootropics back when they were open

4:57 AM

Had some frozen for a while

1

4:57 AM

4'DMA is sublingual in 10mg quantities

JoBro

Today I have received the last of what I need. I will try a stack of ARA-290, P21, Adamax, 4'DMA DHF, MGF, and Novolin-R. Will update as I receive subjective effects.

JoBro

4'DMA is sublingual in 10mg quantities

I open the 8mg ND capsules under the tongue to good effects

Odder_Sea

I open the 8mg ND capsules under the tongue to good effects

They're now 10mg per capsule

JoBro

They're now 10mg per capsule

I've been robbed justno

1

2

1

DFO increases my dopamine release as well but if I take a higher dose than 50 mg I get sedation and psychedelic like effect of microdoses of psychedelics like Ayahuasca.

10:29 AM

The sedation eventually makes me feel anhedonic

10:29 AM

I believe this psychedelic effect is pro-psychosis or at least mania or hypomania.

Meso

DFO increases my dopamine release as well but if I take a higher dose than 50 mg I get sedation and psychedelic like effect of microdoses of psychedelics like Ayahuasca.

Good to hear from you again. Id like to hear more

Meso

I believe this psychedelic effect is pro-psychosis or at least mania or hypomania.

That is strange because DFO blocks manic behavior and psychotic behavior. I also find it psychedelic-like, i have not touched it for a month and am going to do some today. I took 20mg rapamycin intranasal just now, 4th time using rapa. This time seemed to hit pretty hard because i went on a run before hand and been in a energetic mood today

9:41 AM

Wow that rapa rush is so weird, its like staggering augmentation of a bumpy railroad tracks leading to youth god complexion

9:47 AM

You can feel it everywhere in your body, kind of disorienting but gradually augments your abilities and cognition and mind

9:54 AM

Rapamycin was very noticeable at reducing inflammation and making the full-time physical work life more tolerable. It seems like the rapa benefits fade away after a few days but i know its supposed to be taken longterm for the real true benefits.

Deleted User

Rapamycin was very noticeable at reducing inflammation and making the full-time physical work life more tolerable. It seems like the rapa benefits fade away after a few days but i know its supposed to be taken longterm for the real true benefits.

I found a a good physical work stack: Bromantane, L-Tyrosine, and Guarana Extract. My first attempt (today), I dosed at Bromantane 20mg IN, L-Tyrosine 1500mg empty stomach, and 200mg caffeine worth Guarana Extract empty stomach (edited)

That seems nice. I really look forward to your experience with dfo tho

gary88

I found a a good physical work stack: Bromantane, L-Tyrosine, and Guarana Extract. My first attempt (today), I dosed at Bromantane 20mg IN, L-Tyrosine 1500mg empty stomach, and 200mg caffeine worth Guarana Extract empty stomach (edited)

Needs kratom

Nah what we need is to look at opioid peptides kira1

5:17 AM

Rubiscolin?

DFO is on my to-do/to-buy list, probably shortly after chelation with Emeramide

Deleted User

Rubiscolin?

Seen some with little as 2amino acids.

I didn't believe the IN insulin hype until I made a spray recently

5:19 AM

It's probably just a matter of my brain being in worse shape than most and insulin helping shore things up (edited)

Insulin allowed me to literally attract the attention of phd students

Do you have experience with natural preservatives for IN formulations? One issue I've encountered is degradation from (presumably) nasal bacteria. Beta-cyclodextrin and Povidone accelerate it.

5:23 AM

I hesitate to use Benzyl Alcohol since it irritates my skin, at least on my fingers.

5:24 AM

I'm trying to figure out what's better, regular nasal spray or nebulizer

5:24 AM

I did get a ISRIB nasal spray working

gary88

Do you have experience with natural preservatives for IN formulations? One issue I've encountered is degradation from (presumably) nasal bacteria. Beta-cyclodextrin and Povidone accelerate it.

Sodium benzoate? Grape seed extract? Xylitol? D-limonene? Antibacterial metal nanoclusters? Also what did you use for isrib nasal spray ; xclear ?

Put gold shavings in it

Blossoming Tree of Peace

Put gold shavings in it

I stg i was thinking of gold nanoparticles. I was thinking of metals that could help preserve it

Deleted User

I stg i was thinking of gold nanoparticles. I was thinking of metals that could help preserve it

Mimosine capped gold nanoparticles.

Pax1l

Mimosine capped gold nanoparticles.

Where do i get salmon sperm extract i need more a2a for antidepressant effects that replicate a fantasy magical life like im in a game world of nostalgic festive fortuity

1

2:02 AM

Microbiologist demonstrate sperms metabolism, degradation, and structural features that support the conjugation of something like salmon sperm extract to be on linker with succinic acid attached to mimosine capped gold nanoparticles

@DFO its been a while since ive heard from many of you who have formerly given experience reports. I have missed reading about it and seeing new experiences. If any of you have an update please give your latest report.

My entire reward system has been rewritten especially the mesolimbic dopamine pathway Changing my personality and making me a better and more whole person. No longer as enamoured of immediate pleasure or experiences of pleasure as reward, I am driven towards effort and pain in the immediate experience of life mediated by elevated hormones mainly testosterone. I have greater access to pleasure from effort due to these changes in my dopaminergic circuitry. Thereby my time preference is far greater and I don’t find myself intimidated by hours of effort or work, I am eternal, all that exists is the I in this moment, only present experience; I feel this much more now. so now I throw myself into life completely at every moment as much as I can, thereby maximizing my sense of self and the boundaries of my mind. Like Sisyphus I roll this stone up this mountain and when it falls down for the nth time, I am not afraid of the eternity of time nor the suffering it brings, I can already feel the pleasure in my arms aching to carry the weight again.

JoBro

They're now 10mg per capsule

Oral, sublingual, internasal?

Has anyone tried microdosing DFO?

Closest to microdosing in my experience is 5mg intranasally per spray

Pax1l

Closest to microdosing in my experience is 5mg intranasally per spray

and what has been the experience with that?

Nothing