LDH_analysis
ERM
2023-05-17
Last updated: 2023-05-17
Checks: 7 0
Knit directory: Cardiotoxicity/
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##package loading
48 hour Lactate Dehydrogenase results
48 hour viability to LDH activity correlation
####24h LDH data frame
$VDA
Welch Two Sample t-test
data: VE_24_ldh and DA_24_ldh
t = -3.7541, df = 17.12, p-value = 0.001564
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-1.0263033 -0.2880301
sample estimates:
mean of x mean of y
1.012944 1.670111
$VDX
Welch Two Sample t-test
data: VE_24_ldh and DX_24_ldh
t = -3.7427, df = 17.065, p-value = 0.001611
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-1.3902576 -0.3880757
sample estimates:
mean of x mean of y
1.012944 1.902111
$VEP
Welch Two Sample t-test
data: VE_24_ldh and EP_24_ldh
t = -4.285, df = 17.065, p-value = 0.0004969
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-1.5254695 -0.5190861
sample estimates:
mean of x mean of y
1.012944 2.035222
$VMT
Welch Two Sample t-test
data: VE_24_ldh and MT_24_ldh
t = -5.1821, df = 17.085, p-value = 7.383e-05
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-1.5220379 -0.6415176
sample estimates:
mean of x mean of y
1.012944 2.094722
$VTR
Welch Two Sample t-test
data: VE_24_ldh and TR_24_ldh
t = -2.5982, df = 17.112, p-value = 0.01868
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-0.85356981 -0.08876353
sample estimates:
mean of x mean of y
1.012944 1.484111
$VVEH
Welch Two Sample t-test
data: VE_24_ldh and VE_24_ldh
t = 0, df = 34, p-value = 1
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-0.02989169 0.02989169
sample estimates:
mean of x mean of y
1.012944 1.012944 ####24h Tnni data frame
$VDAT
Welch Two Sample t-test
data: VE_24_TNNI and DA_24_TNNI
t = -1.2565, df = 11.832, p-value = 0.2332
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-0.36079840 0.09713173
sample estimates:
mean of x mean of y
0.978500 1.110333
$VDXT
Welch Two Sample t-test
data: VE_24_TNNI and DX_24_TNNI
t = -5.8512, df = 15.728, p-value = 2.633e-05
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-0.3799972 -0.1776694
sample estimates:
mean of x mean of y
0.978500 1.257333
$VEPT
Welch Two Sample t-test
data: VE_24_TNNI and EP_24_TNNI
t = -3.4195, df = 13.915, p-value = 0.004181
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-0.32673646 -0.07476354
sample estimates:
mean of x mean of y
0.97850 1.17925
$VMTT
Welch Two Sample t-test
data: VE_24_TNNI and MT_24_TNNI
t = -4.4919, df = 12.316, p-value = 0.0006915
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-0.5625613 -0.1957720
sample estimates:
mean of x mean of y
0.978500 1.357667
$VTRT
Welch Two Sample t-test
data: VE_24_TNNI and TR_24_TNNI
t = -3.7217, df = 11.904, p-value = 0.002956
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-0.5951287 -0.1553713
sample estimates:
mean of x mean of y
0.97850 1.35375
$VVEHT
Welch Two Sample t-test
data: VE_24_TNNI and VE_24_TNNI
t = 0, df = 34, p-value = 1
alternative hypothesis: true difference in means is not equal to 0
95 percent confidence interval:
-0.0574163 0.0574163
sample estimates:
mean of x mean of y
0.9785 0.9785 ##joint dataframe data
RNA normalized 24 hour cTNNI / LDH
Calcium data at 24 hours
Beat Rate
Mean amplitude
Full-Width-half max
Rising Slope
Decay slope
k means plot
R version 4.2.2 (2022-10-31 ucrt)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19045)
Matrix products: default
locale:
[1] LC_COLLATE=English_United States.utf8
[2] LC_CTYPE=English_United States.utf8
[3] LC_MONETARY=English_United States.utf8
[4] LC_NUMERIC=C
[5] LC_TIME=English_United States.utf8
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] ggalt_0.4.0 RColorBrewer_1.1-3 ggsignif_0.6.4 zoo_1.8-11
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[13] tidyverse_2.0.0 rstatix_0.7.2 ggpubr_0.6.0 ggplot2_3.4.1
[17] readxl_1.4.2 workflowr_1.7.0
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