Last updated: 2023-07-07

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Knit directory: Cardiotoxicity/

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Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes.


These are the previous versions of the repository in which changes were made to the R Markdown (analysis/Figure9.Rmd) and HTML (docs/Figure9.html) files. If you’ve configured a remote Git repository (see ?wflow_git_remote), click on the hyperlinks in the table below to view the files as they were in that past version.

File Version Author Date Message
Rmd 63d054a reneeisnowhere 2023-07-07 Various changes to graphs. pending Monday-renames
html 0e3d22d reneeisnowhere 2023-07-06 Build site.
Rmd 6a6c9af reneeisnowhere 2023-07-06 adding fig 5 and changing fig9 heatmap
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Rmd d7fa0ae reneeisnowhere 2023-07-06 adding heatmaps and plots
Rmd 26c55b3 reneeisnowhere 2023-07-06 adding heatmaps and plots

<environment: R_GlobalEnv>

Figure 9

Genes in CVD and AC toxicity respond to Top2i

A. GWAS chi square results

B. GWAS and TWAS associated genes

C. RARG expression and correlation to TNNI, LD50, and LDH values

D. SLC28A3 expression and correlation to TNNI, LD50, and LDH values

E. TNS2 expression and correlation to TNNI, LD50, and LDH values

F. ZNF740 expression and correlation to TNNI, LD50, and LDH values


R version 4.2.2 (2022-10-31 ucrt)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19045)

Matrix products: default

locale:
[1] LC_COLLATE=English_United States.utf8 
[2] LC_CTYPE=English_United States.utf8   
[3] LC_MONETARY=English_United States.utf8
[4] LC_NUMERIC=C                          
[5] LC_TIME=English_United States.utf8    

attached base packages:
[1] grid      stats     graphics  grDevices utils     datasets  methods  
[8] base     

other attached packages:
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[10] lubridate_1.9.2       forcats_1.0.0         stringr_1.5.0        
[13] dplyr_1.1.2           purrr_1.0.1           readr_2.1.4          
[16] tidyr_1.3.0           tibble_3.2.1          ggplot2_3.4.2        
[19] tidyverse_2.0.0       edgeR_3.38.4          limma_3.52.4         
[22] workflowr_1.7.0      

loaded via a namespace (and not attached):
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[13] R6_2.5.1            sjlabelled_1.2.0    mgcv_1.8-42        
[16] BiocGenerics_0.42.0 colorspace_2.1-0    GetoptLong_1.0.5   
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[22] compiler_4.2.2      git2r_0.32.0        cli_3.6.1          
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[31] digest_0.6.31       rmarkdown_2.22      svglite_2.1.1      
[34] pkgconfig_2.0.3     htmltools_0.5.5     highr_0.10         
[37] fastmap_1.1.1       GlobalOptions_0.1.2 rlang_1.1.1        
[40] rstudioapi_0.14     farver_2.1.1        shape_1.4.6        
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[46] car_3.1-2           magrittr_2.0.3      Matrix_1.5-4.1     
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[52] fansi_1.0.4         abind_1.4-5         lifecycle_1.0.3    
[55] stringi_1.7.12      whisker_0.4.1       yaml_2.3.7         
[58] carData_3.0-5       parallel_4.2.2      promises_1.2.0.1   
[61] crayon_1.5.2        lattice_0.21-8      splines_4.2.2      
[64] circlize_0.4.15     hms_1.1.3           locfit_1.5-9.8     
[67] knitr_1.43          ps_1.7.5            pillar_1.9.0       
[70] rjson_0.2.21        stats4_4.2.2        codetools_0.2-19   
[73] glue_1.6.2          evaluate_0.21       getPass_0.2-2      
[76] vctrs_0.6.3         png_0.1-8           tzdb_0.4.0         
[79] httpuv_1.6.11       foreach_1.5.2       gtable_0.3.3       
[82] clue_0.3-64         cachem_1.0.8        xfun_0.39          
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[88] iterators_1.0.14    IRanges_2.30.1      cluster_2.1.4      
[91] timechange_0.2.0