Last updated: 2023-06-26

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Knit directory: Cardiotoxicity/

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  • Fig S1
  • Fig S10 Drug-specific genes and pathways
  • Fig S12 Cormotif genes
  • Fig S12 Cormotif
  • Fig S2
  • Fig S3
  • Fig S4
  • Fig S5
  • Fig S6
  • Fig S7
  • Fig S8 volcano
  • Fig S9
  • Fig venntimepoints
  • packages

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Unstaged changes:
    Modified:   analysis/Cormotifcluster_analysis.Rmd
    Modified:   analysis/DEG-GO_analysis.Rmd
    Modified:   analysis/DRC_analysis.Rmd
    Modified:   analysis/Knowles2019.Rmd
    Modified:   analysis/LDH_analysis.Rmd
    Modified:   analysis/RNAseqanalysis.Rmd

Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes.


These are the previous versions of the repository in which changes were made to the R Markdown (analysis/Supplementary_figures.Rmd) and HTML (docs/Supplementary_figures.html) files. If you’ve configured a remote Git repository (see ?wflow_git_remote), click on the hyperlinks in the table below to view the files as they were in that past version.

File Version Author Date Message
Rmd 6e50959 reneeisnowhere 2023-06-26 Adding supplementary figures
html dace8ba reneeisnowhere 2023-06-23 Build site.
Rmd 2b109c3 reneeisnowhere 2023-06-23 adding some supp graphs
Rmd c1d667f reneeisnowhere 2023-06-23 updating the codes at Friday start.

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk\(set(autodep = TRUE)</code> at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option <code>dependson</code> for each individual chunk that is cached. Using either <code>autodep</code> or <code>dependson</code> will remove this warning. See the <a href="https://yihui.name/knitr/options/#cache" >knitr cache options</a> for more details. </p> </div> ### Fig. S1 <img src="figure/Supplementary_figures.Rmd/Fig S1-1.svg" width="2100" style="display: block; margin: auto;" /><table class=" lightable-paper lightable-striped table" style='font-family: "Arial Narrow", arial, helvetica, sans-serif; width: auto !important; margin-left: auto; margin-right: auto; font-size: 18px; width: auto !important; margin-left: auto; margin-right: auto;'> <caption style="font-size: initial !important;">Stats summary of cTNNT+ FACs readings</caption> <thead> <tr> <th style="text-align:left;"> </th> <th style="text-align:left;"> Percent </th> <th style="text-align:left;"> Individual </th> </tr> </thead> <tbody> <tr> <td style="text-align:left;"> </td> <td style="text-align:left;"> Min. :63.10 </td> <td style="text-align:left;"> Length:17 </td> </tr> <tr> <td style="text-align:left;"> </td> <td style="text-align:left;"> 1st Qu.:91.80 </td> <td style="text-align:left;"> Class :character </td> </tr> <tr> <td style="text-align:left;"> </td> <td style="text-align:left;"> Median :96.65 </td> <td style="text-align:left;"> Mode :character </td> </tr> <tr> <td style="text-align:left;"> </td> <td style="text-align:left;"> Mean :92.80 </td> <td style="text-align:left;"> NA </td> </tr> <tr> <td style="text-align:left;"> </td> <td style="text-align:left;"> 3rd Qu.:98.50 </td> <td style="text-align:left;"> NA </td> </tr> <tr> <td style="text-align:left;"> </td> <td style="text-align:left;"> Max. :99.90 </td> <td style="text-align:left;"> NA </td> </tr> </tbody> </table> <div class="alert alert-warning"> <p><strong>Warning:</strong> The above code chunk cached its results, but it won't be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set <code>knitr::opts_chunk\)set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S2

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S3

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S4

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S5

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S6

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

heatmap is pending a few changes! just not my focus today.

Fig. S7

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S8

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S9

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk\(set(autodep = TRUE)</code> at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option <code>dependson</code> for each individual chunk that is cached. Using either <code>autodep</code> or <code>dependson</code> will remove this warning. See the <a href="https://yihui.name/knitr/options/#cache" >knitr cache options</a> for more details. </p> </div> ### Fig. S10 <img src="figure/Supplementary_figures.Rmd/Fig S10 Drug-specific genes and pathways-1.svg" width="4200" style="display: block; margin: auto;" /> <div class="alert alert-warning"> <p><strong>Warning:</strong> The above code chunk cached its results, but it won't be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set <code>knitr::opts_chunk\)set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S11

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Fig. S12

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.

<environment: R_GlobalEnv>

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.


R version 4.2.2 (2022-10-31 ucrt)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19045)

Matrix products: default

locale:
[1] LC_COLLATE=English_United States.utf8 
[2] LC_CTYPE=English_United States.utf8   
[3] LC_MONETARY=English_United States.utf8
[4] LC_NUMERIC=C                          
[5] LC_TIME=English_United States.utf8    

attached base packages:
[1] grid      stats     graphics  grDevices utils     datasets  methods  
[8] base     

other attached packages:
 [1] edgeR_3.38.4          limma_3.52.4          cowplot_1.1.1        
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[13] forcats_1.0.0         stringr_1.5.0         dplyr_1.1.2          
[16] purrr_1.0.1           readr_2.1.4           tidyr_1.3.0          
[19] tibble_3.2.1          ggplot2_3.4.2         tidyverse_2.0.0      
[22] workflowr_1.7.0      

loaded via a namespace (and not attached):
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[10] utf8_1.2.3          R6_2.5.1            BiocGenerics_0.42.0
[13] colorspace_2.1-0    GetoptLong_1.0.5    withr_2.5.0        
[16] tidyselect_1.2.0    processx_3.8.1      compiler_4.2.2     
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[25] scales_1.2.1        callr_3.7.3         systemfonts_1.0.4  
[28] digest_0.6.31       rmarkdown_2.22      svglite_2.1.1      
[31] pkgconfig_2.0.3     htmltools_0.5.5     highr_0.10         
[34] fastmap_1.1.1       rlang_1.1.1         GlobalOptions_0.1.2
[37] rstudioapi_0.14     farver_2.1.1        shape_1.4.6        
[40] jquerylib_0.1.4     generics_0.1.3      jsonlite_1.8.5     
[43] car_3.1-2           magrittr_2.0.3      Rcpp_1.0.10        
[46] munsell_0.5.0       S4Vectors_0.34.0    fansi_1.0.4        
[49] abind_1.4-5         lifecycle_1.0.3     stringi_1.7.12     
[52] whisker_0.4.1       yaml_2.3.7          carData_3.0-5      
[55] parallel_4.2.2      promises_1.2.0.1    crayon_1.5.2       
[58] lattice_0.21-8      circlize_0.4.15     hms_1.1.3          
[61] locfit_1.5-9.8      knitr_1.43          ps_1.7.5           
[64] pillar_1.9.0        rjson_0.2.21        stats4_4.2.2       
[67] codetools_0.2-19    glue_1.6.2          evaluate_0.21      
[70] getPass_0.2-2       data.table_1.14.8   vctrs_0.6.3        
[73] png_0.1-8           tzdb_0.4.0          httpuv_1.6.11      
[76] foreach_1.5.2       gtable_0.3.3        clue_0.3-64        
[79] cachem_1.0.8        xfun_0.39           broom_1.0.5        
[82] later_1.3.1         viridisLite_0.4.2   iterators_1.0.14   
[85] IRanges_2.30.1      cluster_2.1.4       timechange_0.2.0   

Warning: The above code chunk cached its results, but it won’t be re-run if previous chunks it depends on are updated. If you need to use caching, it is highly recommended to also set knitr::opts_chunk$set(autodep = TRUE) at the top of the file (in a chunk that is not cached). Alternatively, you can customize the option dependson for each individual chunk that is cached. Using either autodep or dependson will remove this warning. See the knitr cache options for more details.