Last updated: 2025-02-07

Checks: 7 0

Knit directory: multigroup_ctwas_analysis/

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File Version Author Date Message
html 7ff6573 sq-96 2025-02-07 update
html ac24f5c sq-96 2025-02-05 update
Rmd d8219fa sq-96 2025-02-04 update
html d8219fa sq-96 2025-02-04 update
Rmd 218cde2 sq-96 2025-02-04 update
html 218cde2 sq-96 2025-02-04 update
Rmd 5da6635 sq-96 2025-02-04 update
html 5da6635 sq-96 2025-02-04 update
Rmd 3b41f56 sq-96 2025-02-04 update
html 3b41f56 sq-96 2025-02-04 update
html 24afd77 sq-96 2025-02-03 update
Rmd 97b85a5 sq-96 2025-02-03 update
html 97b85a5 sq-96 2025-02-03 update

Parameter estimation on all regions (min_gene=0, min_p_single_effect=0, min_var=1)

Enrichment = 1

Version Author Date
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Enrichment = 10

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Enrichment = 40

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Enrichment = 80

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Gene Prior = 0.00025

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Gene Prior = 0.0025

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Gene Prior = 0.01

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Gene Prior = 0.02

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Gene Variance = 10.2

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97b85a5 sq-96 2025-02-03

Gene Variance = 10.2

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Gene Variance = 10.2

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Gene Variance = 10.2

Version Author Date
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97b85a5 sq-96 2025-02-03

Parameter estimation on selected regions (min_gene=1, min_p_single_effect=0.8, min_var=2)

Enrichment = 1

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97b85a5 sq-96 2025-02-03

Enrichment = 10

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97b85a5 sq-96 2025-02-03

Enrichment = 40

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97b85a5 sq-96 2025-02-03

Enrichment = 80

Version Author Date
97b85a5 sq-96 2025-02-03

Gene Prior = 0.00025

Version Author Date
97b85a5 sq-96 2025-02-03

Gene Prior = 0.0025

Version Author Date
97b85a5 sq-96 2025-02-03

Gene Prior = 0.01

Version Author Date
97b85a5 sq-96 2025-02-03

Gene Prior = 0.02

Version Author Date
97b85a5 sq-96 2025-02-03

Gene Variance = 10.2

Version Author Date
5da6635 sq-96 2025-02-04
97b85a5 sq-96 2025-02-03

Gene Variance = 10.2

Version Author Date
5da6635 sq-96 2025-02-04
97b85a5 sq-96 2025-02-03

Gene Variance = 10.2

Version Author Date
5da6635 sq-96 2025-02-04
97b85a5 sq-96 2025-02-03

Gene Variance = 10.2

Version Author Date
5da6635 sq-96 2025-02-04
97b85a5 sq-96 2025-02-03

PIP calibration (cs index filter)

Enrichment=1 (without cs index filter)

Warning: Using `size` aesthetic for lines was deprecated in ggplot2 3.4.0.
ℹ Please use `linewidth` instead.
This warning is displayed once every 8 hours.
Call `lifecycle::last_lifecycle_warnings()` to see where this warning was
generated.
Warning: The `size` argument of `element_line()` is deprecated as of ggplot2 3.4.0.
ℹ Please use the `linewidth` argument instead.
This warning is displayed once every 8 hours.
Call `lifecycle::last_lifecycle_warnings()` to see where this warning was
generated.
Warning: Removed 6 rows containing missing values or values outside the scale range
(`geom_point()`).
Removed 6 rows containing missing values or values outside the scale range
(`geom_point()`).

Version Author Date
d8219fa sq-96 2025-02-04
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Enrichment=1 (with cs index filter)

Warning: Removed 6 rows containing missing values or values outside the scale range
(`geom_point()`).
Removed 6 rows containing missing values or values outside the scale range
(`geom_point()`).

Version Author Date
d8219fa sq-96 2025-02-04
218cde2 sq-96 2025-02-04

Enrichment=10 (without cs index filter)

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d8219fa sq-96 2025-02-04
218cde2 sq-96 2025-02-04

Enrichment=10 (with cs index filter)

Version Author Date
d8219fa sq-96 2025-02-04
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Enrichment=40 (without cs index filter)

Version Author Date
d8219fa sq-96 2025-02-04

Enrichment=40 (with cs index filter)

Version Author Date
d8219fa sq-96 2025-02-04

Enrichment=80 (without cs index filter)

Version Author Date
7ff6573 sq-96 2025-02-07
d8219fa sq-96 2025-02-04

Enrichment=80 (with cs index filter)

Version Author Date
7ff6573 sq-96 2025-02-07
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sessionInfo()
R version 4.2.0 (2022-04-22)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: CentOS Linux 7 (Core)

Matrix products: default
BLAS/LAPACK: /software/openblas-0.3.13-el7-x86_64/lib/libopenblas_haswellp-r0.3.13.so

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
 [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
 [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C            
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] plyr_1.8.7        plotrix_3.8-2     cowplot_1.1.3     ggpubr_0.6.0     
 [5] ggbreak_0.1.2     data.table_1.16.0 ggplot2_3.5.1     dplyr_1.1.4      
 [9] tidyr_1.3.1       ctwas_0.5.2.9000  workflowr_1.7.0  

loaded via a namespace (and not attached):
  [1] backports_1.4.1             BiocFileCache_2.6.1        
  [3] lazyeval_0.2.2              BiocParallel_1.32.6        
  [5] GenomeInfoDb_1.34.9         LDlinkR_1.4.0              
  [7] digest_0.6.37               yulab.utils_0.1.7          
  [9] ensembldb_2.22.0            htmltools_0.5.8.1          
 [11] fansi_1.0.6                 magrittr_2.0.3             
 [13] memoise_2.0.1               tzdb_0.4.0                 
 [15] Biostrings_2.66.0           readr_2.1.5                
 [17] matrixStats_1.4.1           locuszoomr_0.3.5           
 [19] prettyunits_1.2.0           colorspace_2.1-1           
 [21] blob_1.2.4                  rappdirs_0.3.3             
 [23] ggrepel_0.9.6               xfun_0.47                  
 [25] callr_3.7.2                 crayon_1.5.3               
 [27] RCurl_1.98-1.16             jsonlite_1.8.9             
 [29] zoo_1.8-12                  glue_1.7.0                 
 [31] gtable_0.3.5                zlibbioc_1.44.0            
 [33] XVector_0.38.0              DelayedArray_0.24.0        
 [35] car_3.1-1                   BiocGenerics_0.44.0        
 [37] abind_1.4-5                 scales_1.3.0               
 [39] DBI_1.2.3                   rstatix_0.7.2              
 [41] Rcpp_1.0.13                 viridisLite_0.4.2          
 [43] progress_1.2.3              gridGraphics_0.5-1         
 [45] bit_4.5.0                   stats4_4.2.0               
 [47] htmlwidgets_1.6.4           httr_1.4.7                 
 [49] pkgconfig_2.0.3             XML_3.99-0.14              
 [51] farver_2.1.2                sass_0.4.9                 
 [53] dbplyr_2.5.0                utf8_1.2.4                 
 [55] labeling_0.4.3              ggplotify_0.1.2            
 [57] tidyselect_1.2.1            rlang_1.1.4                
 [59] later_1.3.2                 AnnotationDbi_1.60.2       
 [61] munsell_0.5.1               pgenlibr_0.3.7             
 [63] tools_4.2.0                 cachem_1.1.0               
 [65] cli_3.6.3                   generics_0.1.3             
 [67] RSQLite_2.3.7               broom_1.0.5                
 [69] evaluate_1.0.0              stringr_1.5.1              
 [71] fastmap_1.2.0               yaml_2.3.10                
 [73] processx_3.7.0              knitr_1.48                 
 [75] bit64_4.5.2                 fs_1.6.4                   
 [77] purrr_1.0.2                 KEGGREST_1.38.0            
 [79] AnnotationFilter_1.22.0     whisker_0.4                
 [81] aplot_0.2.3                 xml2_1.3.3                 
 [83] biomaRt_2.54.1              compiler_4.2.0             
 [85] rstudioapi_0.14             plotly_4.10.4              
 [87] filelock_1.0.3              curl_5.2.3                 
 [89] png_0.1-7                   ggsignif_0.6.3             
 [91] tibble_3.2.1                bslib_0.8.0                
 [93] stringi_1.8.4               highr_0.11                 
 [95] ps_1.7.1                    GenomicFeatures_1.50.4     
 [97] lattice_0.20-45             ProtGenerics_1.30.0        
 [99] Matrix_1.5-3                vctrs_0.6.5                
[101] pillar_1.9.0                lifecycle_1.0.4            
[103] jquerylib_0.1.4             bitops_1.0-8               
[105] irlba_2.3.5.1               httpuv_1.6.5               
[107] patchwork_1.3.0             rtracklayer_1.58.0         
[109] GenomicRanges_1.50.2        R6_2.5.1                   
[111] BiocIO_1.8.0                promises_1.3.0             
[113] gridExtra_2.3               IRanges_2.32.0             
[115] codetools_0.2-18            SummarizedExperiment_1.28.0
[117] rprojroot_2.0.3             rjson_0.2.23               
[119] withr_3.0.1                 GenomicAlignments_1.34.1   
[121] Rsamtools_2.14.0            S4Vectors_0.36.2           
[123] GenomeInfoDbData_1.2.9      parallel_4.2.0             
[125] hms_1.1.3                   grid_4.2.0                 
[127] ggfun_0.1.6                 gggrid_0.2-0               
[129] rmarkdown_2.28              MatrixGenerics_1.10.0      
[131] carData_3.0-5               logging_0.10-108           
[133] git2r_0.30.1                mixsqp_0.3-54              
[135] getPass_0.2-2               Biobase_2.58.0             
[137] restfulr_0.0.15