Last updated: 2025-04-03

Checks: 6 1

Knit directory: multigroup_ctwas_analysis/

This reproducible R Markdown analysis was created with workflowr (version 1.7.0). The Checks tab describes the reproducibility checks that were applied when the results were created. The Past versions tab lists the development history.


The R Markdown file has unstaged changes. To know which version of the R Markdown file created these results, you’ll want to first commit it to the Git repo. If you’re still working on the analysis, you can ignore this warning. When you’re finished, you can run wflow_publish to commit the R Markdown file and build the HTML.

Great job! The global environment was empty. Objects defined in the global environment can affect the analysis in your R Markdown file in unknown ways. For reproduciblity it’s best to always run the code in an empty environment.

The command set.seed(20231112) was run prior to running the code in the R Markdown file. Setting a seed ensures that any results that rely on randomness, e.g. subsampling or permutations, are reproducible.

Great job! Recording the operating system, R version, and package versions is critical for reproducibility.

Nice! There were no cached chunks for this analysis, so you can be confident that you successfully produced the results during this run.

Great job! Using relative paths to the files within your workflowr project makes it easier to run your code on other machines.

Great! You are using Git for version control. Tracking code development and connecting the code version to the results is critical for reproducibility.

The results in this page were generated with repository version af39d3d. See the Past versions tab to see a history of the changes made to the R Markdown and HTML files.

Note that you need to be careful to ensure that all relevant files for the analysis have been committed to Git prior to generating the results (you can use wflow_publish or wflow_git_commit). workflowr only checks the R Markdown file, but you know if there are other scripts or data files that it depends on. Below is the status of the Git repository when the results were generated:


Unstaged changes:
    Modified:   analysis/simulation_one_tissue_no_enrichment.Rmd

Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes.


These are the previous versions of the repository in which changes were made to the R Markdown (analysis/simulation_one_tissue_no_enrichment.Rmd) and HTML (docs/simulation_one_tissue_no_enrichment.html) files. If you’ve configured a remote Git repository (see ?wflow_git_remote), click on the hyperlinks in the table below to view the files as they were in that past version.

File Version Author Date Message
Rmd 4ef57f5 sq-96 2025-03-26 update
Rmd 3a5cb13 sq-96 2025-03-20 update
html 3a5cb13 sq-96 2025-03-20 update
Rmd 33bf7ea sq-96 2025-03-19 update
html 33bf7ea sq-96 2025-03-19 update
Rmd e2ef641 sq-96 2025-03-18 update
html e2ef641 sq-96 2025-03-18 update

One tissue simulation


Attaching package: 'dplyr'
The following objects are masked from 'package:stats':

    filter, lag
The following objects are masked from 'package:base':

    intersect, setdiff, setequal, union

Attaching package: 'data.table'
The following objects are masked from 'package:dplyr':

    between, first, last
ggbreak v0.1.2

If you use ggbreak in published research, please cite the following
paper:

S Xu, M Chen, T Feng, L Zhan, L Zhou, G Yu. Use ggbreak to effectively
utilize plotting space to deal with large datasets and outliers.
Frontiers in Genetics. 2021, 12:774846. doi: 10.3389/fgene.2021.774846

Attaching package: 'gridExtra'
The following object is masked from 'package:dplyr':

    combine

Attaching package: 'cowplot'
The following object is masked from 'package:ggpubr':

    get_legend
------------------------------------------------------------------------------
You have loaded plyr after dplyr - this is likely to cause problems.
If you need functions from both plyr and dplyr, please load plyr first, then dplyr:
library(plyr); library(dplyr)
------------------------------------------------------------------------------

Attaching package: 'plyr'
The following object is masked from 'package:ggpubr':

    mutate
The following objects are masked from 'package:dplyr':

    arrange, count, desc, failwith, id, mutate, rename, summarise,
    summarize

Enrichment=1

Version Author Date
3a5cb13 sq-96 2025-03-20
e2ef641 sq-96 2025-03-18

Prior Inclusion Probability

Version Author Date
3a5cb13 sq-96 2025-03-20
33bf7ea sq-96 2025-03-19

Prior Variance

Version Author Date
3a5cb13 sq-96 2025-03-20
e2ef641 sq-96 2025-03-18

Enrichment=10

Version Author Date
3a5cb13 sq-96 2025-03-20
33bf7ea sq-96 2025-03-19
e2ef641 sq-96 2025-03-18

Prior Inclusion Probability

Version Author Date
3a5cb13 sq-96 2025-03-20

Prior Variance

Version Author Date
33bf7ea sq-96 2025-03-19
e2ef641 sq-96 2025-03-18

Enrichment=20

Version Author Date
3a5cb13 sq-96 2025-03-20

Prior Inclusion Probability

Version Author Date
3a5cb13 sq-96 2025-03-20
33bf7ea sq-96 2025-03-19

Prior Variance

Version Author Date
3a5cb13 sq-96 2025-03-20
33bf7ea sq-96 2025-03-19

Enrichment=40

Version Author Date
3a5cb13 sq-96 2025-03-20
33bf7ea sq-96 2025-03-19

Prior Inclusion Probability

Version Author Date
33bf7ea sq-96 2025-03-19

Prior Variance

Version Author Date
3a5cb13 sq-96 2025-03-20

Enrichment=80

Version Author Date
3a5cb13 sq-96 2025-03-20
33bf7ea sq-96 2025-03-19

Prior Inclusion Probability

Version Author Date
3a5cb13 sq-96 2025-03-20

Prior Variance

Version Author Date
3a5cb13 sq-96 2025-03-20
33bf7ea sq-96 2025-03-19

sessionInfo()
R version 4.2.0 (2022-04-22)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: CentOS Linux 7 (Core)

Matrix products: default
BLAS/LAPACK: /software/openblas-0.3.13-el7-x86_64/lib/libopenblas_haswellp-r0.3.13.so

locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
 [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
 [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C            
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] plyr_1.8.7        plotrix_3.8-2     cowplot_1.1.3     gridExtra_2.3    
 [5] ggpubr_0.6.0      ggbreak_0.1.2     data.table_1.16.0 ggplot2_3.5.1    
 [9] dplyr_1.1.4       tidyr_1.3.1       ctwas_0.5.4.9000  workflowr_1.7.0  

loaded via a namespace (and not attached):
  [1] backports_1.4.1             BiocFileCache_2.6.1        
  [3] repr_1.1.4                  lazyeval_0.2.2             
  [5] BiocParallel_1.32.6         GenomeInfoDb_1.34.9        
  [7] LDlinkR_1.4.0               digest_0.6.37              
  [9] yulab.utils_0.1.7           ensembldb_2.22.0           
 [11] htmltools_0.5.8.1           fansi_1.0.6                
 [13] magrittr_2.0.3              memoise_2.0.1              
 [15] tzdb_0.4.0                  Biostrings_2.66.0          
 [17] readr_2.1.5                 AMR_2.1.1                  
 [19] matrixStats_1.4.1           locuszoomr_0.3.5           
 [21] prettyunits_1.2.0           colorspace_2.1-1           
 [23] skimr_2.1.4                 blob_1.2.4                 
 [25] rappdirs_0.3.3              ggrepel_0.9.6              
 [27] xfun_0.47                   callr_3.7.2                
 [29] crayon_1.5.3                RCurl_1.98-1.16            
 [31] jsonlite_1.8.9              zoo_1.8-12                 
 [33] glue_1.7.0                  gtable_0.3.5               
 [35] zlibbioc_1.44.0             XVector_0.38.0             
 [37] DelayedArray_0.24.0         car_3.1-1                  
 [39] BiocGenerics_0.44.0         abind_1.4-5                
 [41] scales_1.3.0                DBI_1.2.3                  
 [43] rstatix_0.7.2               Rcpp_1.0.13                
 [45] viridisLite_0.4.2           progress_1.2.3             
 [47] gridGraphics_0.5-1          bit_4.5.0                  
 [49] stats4_4.2.0                htmlwidgets_1.6.4          
 [51] httr_1.4.7                  pkgconfig_2.0.3            
 [53] XML_3.99-0.14               farver_2.1.2               
 [55] sass_0.4.9                  dbplyr_2.5.0               
 [57] utf8_1.2.4                  labeling_0.4.3             
 [59] ggplotify_0.1.2             tidyselect_1.2.1           
 [61] rlang_1.1.4                 later_1.3.2                
 [63] AnnotationDbi_1.60.2        munsell_0.5.1              
 [65] pgenlibr_0.3.7              tools_4.2.0                
 [67] cachem_1.1.0                cli_3.6.3                  
 [69] generics_0.1.3              RSQLite_2.3.7              
 [71] broom_1.0.5                 evaluate_1.0.0             
 [73] stringr_1.5.1               fastmap_1.2.0              
 [75] yaml_2.3.10                 processx_3.7.0             
 [77] knitr_1.48                  bit64_4.5.2                
 [79] fs_1.6.4                    purrr_1.0.2                
 [81] KEGGREST_1.38.0             AnnotationFilter_1.22.0    
 [83] whisker_0.4                 aplot_0.2.3                
 [85] xml2_1.3.3                  biomaRt_2.54.1             
 [87] compiler_4.2.0              rstudioapi_0.14            
 [89] plotly_4.10.4               filelock_1.0.3             
 [91] curl_5.2.3                  png_0.1-7                  
 [93] ggsignif_0.6.3              tibble_3.2.1               
 [95] bslib_0.8.0                 stringi_1.8.4              
 [97] highr_0.11                  ps_1.7.1                   
 [99] GenomicFeatures_1.50.4      lattice_0.20-45            
[101] ProtGenerics_1.30.0         Matrix_1.5-3               
[103] vctrs_0.6.5                 pillar_1.9.0               
[105] lifecycle_1.0.4             jquerylib_0.1.4            
[107] bitops_1.0-8                irlba_2.3.5.1              
[109] httpuv_1.6.5                patchwork_1.3.0            
[111] rtracklayer_1.58.0          GenomicRanges_1.50.2       
[113] R6_2.5.1                    BiocIO_1.8.0               
[115] promises_1.3.0              IRanges_2.32.0             
[117] codetools_0.2-18            SummarizedExperiment_1.28.0
[119] rprojroot_2.0.3             rjson_0.2.23               
[121] withr_3.0.1                 GenomicAlignments_1.34.1   
[123] Rsamtools_2.14.0            S4Vectors_0.36.2           
[125] GenomeInfoDbData_1.2.9      parallel_4.2.0             
[127] hms_1.1.3                   grid_4.2.0                 
[129] ggfun_0.1.6                 gggrid_0.2-0               
[131] rmarkdown_2.28              carData_3.0-5              
[133] MatrixGenerics_1.10.0       logging_0.10-108           
[135] git2r_0.30.1                mixsqp_0.3-54              
[137] getPass_0.2-2               Biobase_2.58.0             
[139] base64enc_0.1-3             restfulr_0.0.15