Last updated: 2020-03-01
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Knit directory: mmbr-rss-dsc/ 
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This is result from our first M&M RSS simulation.
There are 200 data sets, each with 1 causal SNP shared across conditions. The number of conditions are 5 and 10.
library(dplyr)
library(kableExtra)
library(knitr)
out = readRDS('output/mnm_rss_lite_output.20200229.rds')
res = out[,-1]
colnames(res) = c('n_traits', 'method', 'resid_method', 'L', 'prior.scale','total', 'valid', 'size', 'purity', 'top_hit', 'total_true', 'total_true_included', 'overlap_var', 'overlap_cs', 'false_positive_cross_cond', 'false_negative_cross_cond', 'true_positive_cross_cond', 'converged', 'filename')
res$resid_method[res$resid_method == 'diag'] = 'identity'
res.prior.simulated = res %>% filter(prior.scale == 'simulated' | is.na(prior.scale))
res.prior.size = res %>% filter(prior.scale == 'size' | is.na(prior.scale))
res.prior.oracle = res %>% filter(prior.scale == 'oracle' | is.na(prior.scale))
rm(out)
purity = aggregate(purity~n_traits + resid_method + method + L, res.prior.simulated, mean)
purity = purity[order(purity$n_traits, purity$L),]
rownames(purity) = NULL
knitr::kable(purity) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | purity | 
|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 0.1655099 | 
| 5 | identity | mnm_rss_shared | 1 | 0.9856530 | 
| 5 | null | mnm_rss_shared | 1 | 0.9007187 | 
| 5 | oracle | mnm_rss_shared | 1 | 0.9879269 | 
| 5 | flash | mnm_shared | 1 | 0.9941027 | 
| 5 | oracle | mnm_shared | 1 | 0.9965768 | 
| 5 | all | mnm_rss_shared | 2 | 0.1481444 | 
| 5 | identity | mnm_rss_shared | 2 | 0.9659861 | 
| 5 | null | mnm_rss_shared | 2 | 0.8563740 | 
| 5 | oracle | mnm_rss_shared | 2 | 0.9699972 | 
| 5 | flash | mnm_shared | 2 | 0.9941027 | 
| 5 | oracle | mnm_shared | 2 | 0.9965768 | 
| 5 | all | mnm_rss_shared | 10 | 0.0659099 | 
| 5 | identity | mnm_rss_shared | 10 | 0.2548392 | 
| 5 | null | mnm_rss_shared | 10 | 0.2255097 | 
| 5 | oracle | mnm_rss_shared | 10 | 0.3947844 | 
| 5 | flash | mnm_shared | 10 | 0.9941027 | 
| 5 | oracle | mnm_shared | 10 | 0.9965768 | 
| 10 | all | mnm_rss_shared | 1 | 0.4304852 | 
| 10 | identity | mnm_rss_shared | 1 | 0.9891525 | 
| 10 | null | mnm_rss_shared | 1 | 0.9832247 | 
| 10 | oracle | mnm_rss_shared | 1 | 0.9899473 | 
| 10 | flash | mnm_shared | 1 | 0.9965968 | 
| 10 | oracle | mnm_shared | 1 | 0.9986715 | 
| 10 | all | mnm_rss_shared | 2 | 0.3704374 | 
| 10 | identity | mnm_rss_shared | 2 | 0.9796532 | 
| 10 | null | mnm_rss_shared | 2 | 0.9734047 | 
| 10 | oracle | mnm_rss_shared | 2 | 0.9842392 | 
| 10 | flash | mnm_shared | 2 | 0.9965968 | 
| 10 | oracle | mnm_shared | 2 | 0.9986715 | 
| 10 | all | mnm_rss_shared | 10 | 0.2043153 | 
| 10 | identity | mnm_rss_shared | 10 | 0.9216859 | 
| 10 | null | mnm_rss_shared | 10 | 0.8481309 | 
| 10 | oracle | mnm_rss_shared | 10 | 0.9384956 | 
| 10 | flash | mnm_shared | 10 | 0.9965968 | 
| 10 | oracle | mnm_shared | 10 | 0.9986715 | 
total_true_included = aggregate(total_true_included ~ n_traits + resid_method + method + L, res.prior.simulated, sum)
total_true = aggregate(total_true ~  n_traits + resid_method + method + L, res.prior.simulated, sum)
cs_overlap = aggregate(overlap_cs ~  n_traits + resid_method + method + L, res.prior.simulated, sum)
snp_overlap = aggregate(overlap_var ~  n_traits + resid_method + method + L, res.prior.simulated, sum)
power = merge(total_true_included, total_true, by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power = merge(power, cs_overlap,  by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power = merge(power, snp_overlap,  by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power$power = round(power$total_true_included/power$total_true,3)
power$overlap_cs = round(power$overlap_cs, 3)
power$overlap_var = round(power$overlap_var, 3)
power = power[order(power$n_traits, power$L, power$method),]
rownames(power) = NULL
knitr::kable(power) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | total_true_included | total_true | overlap_cs | overlap_var | power | 
|---|---|---|---|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 17 | 200 | 0 | 0 | 0.085 | 
| 5 | identity | mnm_rss_shared | 1 | 199 | 200 | 0 | 0 | 0.995 | 
| 5 | null | mnm_rss_shared | 1 | 178 | 200 | 0 | 0 | 0.890 | 
| 5 | oracle | mnm_rss_shared | 1 | 199 | 200 | 0 | 0 | 0.995 | 
| 5 | flash | mnm_shared | 1 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 1 | 195 | 200 | 0 | 0 | 0.975 | 
| 5 | all | mnm_rss_shared | 2 | 13 | 200 | 1 | 1 | 0.065 | 
| 5 | identity | mnm_rss_shared | 2 | 199 | 200 | 1 | 18 | 0.995 | 
| 5 | null | mnm_rss_shared | 2 | 172 | 200 | 3 | 41 | 0.860 | 
| 5 | oracle | mnm_rss_shared | 2 | 199 | 200 | 2 | 52 | 0.995 | 
| 5 | flash | mnm_shared | 2 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 2 | 195 | 200 | 0 | 0 | 0.975 | 
| 5 | all | mnm_rss_shared | 10 | 3 | 200 | 0 | 0 | 0.015 | 
| 5 | identity | mnm_rss_shared | 10 | 68 | 200 | 267 | 12340 | 0.340 | 
| 5 | null | mnm_rss_shared | 10 | 50 | 200 | 191 | 8724 | 0.250 | 
| 5 | oracle | mnm_rss_shared | 10 | 104 | 200 | 465 | 17077 | 0.520 | 
| 5 | flash | mnm_shared | 10 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 10 | 195 | 200 | 0 | 0 | 0.975 | 
| 10 | all | mnm_rss_shared | 1 | 32 | 200 | 0 | 0 | 0.160 | 
| 10 | identity | mnm_rss_shared | 1 | 194 | 200 | 0 | 0 | 0.970 | 
| 10 | null | mnm_rss_shared | 1 | 165 | 200 | 0 | 0 | 0.825 | 
| 10 | oracle | mnm_rss_shared | 1 | 193 | 200 | 0 | 0 | 0.965 | 
| 10 | flash | mnm_shared | 1 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 1 | 198 | 200 | 0 | 0 | 0.990 | 
| 10 | all | mnm_rss_shared | 2 | 24 | 200 | 5 | 105 | 0.120 | 
| 10 | identity | mnm_rss_shared | 2 | 197 | 200 | 6 | 120 | 0.985 | 
| 10 | null | mnm_rss_shared | 2 | 170 | 200 | 9 | 137 | 0.850 | 
| 10 | oracle | mnm_rss_shared | 2 | 197 | 200 | 12 | 168 | 0.985 | 
| 10 | flash | mnm_shared | 2 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 2 | 198 | 200 | 0 | 0 | 0.990 | 
| 10 | all | mnm_rss_shared | 10 | 11 | 200 | 3 | 17 | 0.055 | 
| 10 | identity | mnm_rss_shared | 10 | 194 | 200 | 276 | 5802 | 0.970 | 
| 10 | null | mnm_rss_shared | 10 | 159 | 200 | 215 | 4618 | 0.795 | 
| 10 | oracle | mnm_rss_shared | 10 | 196 | 200 | 209 | 4062 | 0.980 | 
| 10 | flash | mnm_shared | 10 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 10 | 198 | 200 | 0 | 0 | 0.990 | 
valid = aggregate(valid ~ n_traits + resid_method + method + L, res.prior.simulated, sum)
total = aggregate(total ~ n_traits + resid_method + method + L, res.prior.simulated, sum)
fdr = merge(valid, total, by = c( 'n_traits' , 'resid_method' , 'method', 'L'))
fdr$fdr = round((fdr$total - fdr$valid)/fdr$total,3)
fdr = fdr[order(fdr$n_traits, fdr$L, fdr$method),]
rownames(fdr) = NULL
knitr::kable(fdr) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | valid | total | fdr | 
|---|---|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 17 | 37 | 0.541 | 
| 5 | identity | mnm_rss_shared | 1 | 199 | 200 | 0.005 | 
| 5 | null | mnm_rss_shared | 1 | 178 | 188 | 0.053 | 
| 5 | oracle | mnm_rss_shared | 1 | 199 | 200 | 0.005 | 
| 5 | flash | mnm_shared | 1 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 1 | 195 | 200 | 0.025 | 
| 5 | all | mnm_rss_shared | 2 | 14 | 40 | 0.650 | 
| 5 | identity | mnm_rss_shared | 2 | 200 | 200 | 0.000 | 
| 5 | null | mnm_rss_shared | 2 | 175 | 190 | 0.079 | 
| 5 | oracle | mnm_rss_shared | 2 | 201 | 201 | 0.000 | 
| 5 | flash | mnm_shared | 2 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 2 | 195 | 200 | 0.025 | 
| 5 | all | mnm_rss_shared | 10 | 3 | 83 | 0.964 | 
| 5 | identity | mnm_rss_shared | 10 | 190 | 190 | 0.000 | 
| 5 | null | mnm_rss_shared | 10 | 130 | 190 | 0.316 | 
| 5 | oracle | mnm_rss_shared | 10 | 311 | 311 | 0.000 | 
| 5 | flash | mnm_shared | 10 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 10 | 195 | 200 | 0.025 | 
| 10 | all | mnm_rss_shared | 1 | 32 | 94 | 0.660 | 
| 10 | identity | mnm_rss_shared | 1 | 194 | 199 | 0.025 | 
| 10 | null | mnm_rss_shared | 1 | 165 | 198 | 0.167 | 
| 10 | oracle | mnm_rss_shared | 1 | 193 | 199 | 0.030 | 
| 10 | flash | mnm_shared | 1 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 1 | 198 | 200 | 0.010 | 
| 10 | all | mnm_rss_shared | 2 | 27 | 100 | 0.730 | 
| 10 | identity | mnm_rss_shared | 2 | 203 | 204 | 0.005 | 
| 10 | null | mnm_rss_shared | 2 | 177 | 239 | 0.259 | 
| 10 | oracle | mnm_rss_shared | 2 | 209 | 211 | 0.009 | 
| 10 | flash | mnm_shared | 2 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 2 | 198 | 200 | 0.010 | 
| 10 | all | mnm_rss_shared | 10 | 13 | 160 | 0.919 | 
| 10 | identity | mnm_rss_shared | 10 | 349 | 349 | 0.000 | 
| 10 | null | mnm_rss_shared | 10 | 269 | 590 | 0.544 | 
| 10 | oracle | mnm_rss_shared | 10 | 313 | 313 | 0.000 | 
| 10 | flash | mnm_shared | 10 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 10 | 198 | 200 | 0.010 | 
elbo_converged = aggregate(converged~n_traits + resid_method + method + L, res.prior.simulated, mean)
elbo_converged = elbo_converged[which(elbo_converged$L!=1),]
elbo_converged = elbo_converged[order(elbo_converged$n_traits),]
rownames(elbo_converged) = NULL
knitr::kable(elbo_converged) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24), background = "wheat")
| n_traits | resid_method | method | L | converged | 
|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 2 | 1.000 | 
| 5 | identity | mnm_rss_shared | 2 | 1.000 | 
| 5 | null | mnm_rss_shared | 2 | 1.000 | 
| 5 | oracle | mnm_rss_shared | 2 | 1.000 | 
| 5 | flash | mnm_shared | 2 | 0.955 | 
| 5 | oracle | mnm_shared | 2 | 0.930 | 
| 5 | all | mnm_rss_shared | 10 | 1.000 | 
| 5 | identity | mnm_rss_shared | 10 | 0.700 | 
| 5 | null | mnm_rss_shared | 10 | 0.855 | 
| 5 | oracle | mnm_rss_shared | 10 | 0.505 | 
| 5 | flash | mnm_shared | 10 | 0.955 | 
| 5 | oracle | mnm_shared | 10 | 0.930 | 
| 10 | all | mnm_rss_shared | 2 | 1.000 | 
| 10 | identity | mnm_rss_shared | 2 | 1.000 | 
| 10 | null | mnm_rss_shared | 2 | 1.000 | 
| 10 | oracle | mnm_rss_shared | 2 | 1.000 | 
| 10 | flash | mnm_shared | 2 | 0.915 | 
| 10 | oracle | mnm_shared | 2 | 0.905 | 
| 10 | all | mnm_rss_shared | 10 | 0.980 | 
| 10 | identity | mnm_rss_shared | 10 | 0.030 | 
| 10 | null | mnm_rss_shared | 10 | 0.510 | 
| 10 | oracle | mnm_rss_shared | 10 | 0.020 | 
| 10 | flash | mnm_shared | 10 | 0.915 | 
| 10 | oracle | mnm_shared | 10 | 0.905 | 
purity = aggregate(purity~n_traits + resid_method + method + L, res.prior.size, mean)
purity = purity[order(purity$n_traits, purity$L),]
rownames(purity) = NULL
knitr::kable(purity) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | purity | 
|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 0.9253474 | 
| 5 | identity | mnm_rss_shared | 1 | 0.9960291 | 
| 5 | null | mnm_rss_shared | 1 | 0.9831272 | 
| 5 | oracle | mnm_rss_shared | 1 | 0.9962116 | 
| 5 | flash | mnm_shared | 1 | 0.9941027 | 
| 5 | oracle | mnm_shared | 1 | 0.9965768 | 
| 5 | all | mnm_rss_shared | 2 | 0.9883732 | 
| 5 | identity | mnm_rss_shared | 2 | 0.9936497 | 
| 5 | null | mnm_rss_shared | 2 | 0.9792400 | 
| 5 | oracle | mnm_rss_shared | 2 | 0.9924485 | 
| 5 | flash | mnm_shared | 2 | 0.9941027 | 
| 5 | oracle | mnm_shared | 2 | 0.9965768 | 
| 5 | all | mnm_rss_shared | 10 | 0.9976531 | 
| 5 | identity | mnm_rss_shared | 10 | 0.9934514 | 
| 5 | null | mnm_rss_shared | 10 | 0.9829585 | 
| 5 | oracle | mnm_rss_shared | 10 | 0.9914243 | 
| 5 | flash | mnm_shared | 10 | 0.9941027 | 
| 5 | oracle | mnm_shared | 10 | 0.9965768 | 
| 10 | all | mnm_rss_shared | 1 | 0.9608779 | 
| 10 | identity | mnm_rss_shared | 1 | 0.9975859 | 
| 10 | null | mnm_rss_shared | 1 | 0.9958050 | 
| 10 | oracle | mnm_rss_shared | 1 | 0.9977314 | 
| 10 | flash | mnm_shared | 1 | 0.9965968 | 
| 10 | oracle | mnm_shared | 1 | 0.9986715 | 
| 10 | all | mnm_rss_shared | 2 | 0.9978111 | 
| 10 | identity | mnm_rss_shared | 2 | 0.9951683 | 
| 10 | null | mnm_rss_shared | 2 | 0.9899097 | 
| 10 | oracle | mnm_rss_shared | 2 | 0.9964637 | 
| 10 | flash | mnm_shared | 2 | 0.9965968 | 
| 10 | oracle | mnm_shared | 2 | 0.9986715 | 
| 10 | all | mnm_rss_shared | 10 | 1.0000000 | 
| 10 | identity | mnm_rss_shared | 10 | 0.9958573 | 
| 10 | null | mnm_rss_shared | 10 | 0.9944488 | 
| 10 | oracle | mnm_rss_shared | 10 | 0.9950210 | 
| 10 | flash | mnm_shared | 10 | 0.9965968 | 
| 10 | oracle | mnm_shared | 10 | 0.9986715 | 
total_true_included = aggregate(total_true_included ~ n_traits + resid_method + method + L, res.prior.size, sum)
total_true = aggregate(total_true ~  n_traits + resid_method + method + L, res.prior.size, sum)
cs_overlap = aggregate(overlap_cs ~  n_traits + resid_method + method + L, res.prior.size, sum)
snp_overlap = aggregate(overlap_var ~  n_traits + resid_method + method + L, res.prior.size, sum)
power = merge(total_true_included, total_true, by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power = merge(power, cs_overlap,  by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power = merge(power, snp_overlap,  by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power$power = round(power$total_true_included/power$total_true,3)
power$overlap_cs = round(power$overlap_cs, 3)
power$overlap_var = round(power$overlap_var, 3)
power = power[order(power$n_traits, power$L, power$method),]
rownames(power) = NULL
knitr::kable(power) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | total_true_included | total_true | overlap_cs | overlap_var | power | 
|---|---|---|---|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 49 | 200 | 0 | 0 | 0.245 | 
| 5 | identity | mnm_rss_shared | 1 | 192 | 200 | 0 | 0 | 0.960 | 
| 5 | null | mnm_rss_shared | 1 | 168 | 200 | 0 | 0 | 0.840 | 
| 5 | oracle | mnm_rss_shared | 1 | 191 | 200 | 0 | 0 | 0.955 | 
| 5 | flash | mnm_shared | 1 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 1 | 195 | 200 | 0 | 0 | 0.975 | 
| 5 | all | mnm_rss_shared | 2 | 57 | 200 | 0 | 0 | 0.285 | 
| 5 | identity | mnm_rss_shared | 2 | 193 | 200 | 5 | 41 | 0.965 | 
| 5 | null | mnm_rss_shared | 2 | 169 | 200 | 2 | 35 | 0.845 | 
| 5 | oracle | mnm_rss_shared | 2 | 192 | 200 | 8 | 50 | 0.960 | 
| 5 | flash | mnm_shared | 2 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 2 | 195 | 200 | 0 | 0 | 0.975 | 
| 5 | all | mnm_rss_shared | 10 | 70 | 200 | 3 | 5 | 0.350 | 
| 5 | identity | mnm_rss_shared | 10 | 192 | 200 | 7 | 191 | 0.960 | 
| 5 | null | mnm_rss_shared | 10 | 170 | 200 | 7 | 151 | 0.850 | 
| 5 | oracle | mnm_rss_shared | 10 | 192 | 200 | 8 | 162 | 0.960 | 
| 5 | flash | mnm_shared | 10 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 10 | 195 | 200 | 0 | 0 | 0.975 | 
| 10 | all | mnm_rss_shared | 1 | 42 | 200 | 0 | 0 | 0.210 | 
| 10 | identity | mnm_rss_shared | 1 | 187 | 200 | 0 | 0 | 0.935 | 
| 10 | null | mnm_rss_shared | 1 | 155 | 200 | 0 | 0 | 0.775 | 
| 10 | oracle | mnm_rss_shared | 1 | 187 | 200 | 0 | 0 | 0.935 | 
| 10 | flash | mnm_shared | 1 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 1 | 198 | 200 | 0 | 0 | 0.990 | 
| 10 | all | mnm_rss_shared | 2 | 48 | 200 | 0 | 0 | 0.240 | 
| 10 | identity | mnm_rss_shared | 2 | 187 | 200 | 12 | 107 | 0.935 | 
| 10 | null | mnm_rss_shared | 2 | 154 | 200 | 4 | 35 | 0.770 | 
| 10 | oracle | mnm_rss_shared | 2 | 187 | 200 | 12 | 101 | 0.935 | 
| 10 | flash | mnm_shared | 2 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 2 | 198 | 200 | 0 | 0 | 0.990 | 
| 10 | all | mnm_rss_shared | 10 | 50 | 200 | 0 | 0 | 0.250 | 
| 10 | identity | mnm_rss_shared | 10 | 187 | 200 | 40 | 879 | 0.935 | 
| 10 | null | mnm_rss_shared | 10 | 154 | 200 | 32 | 660 | 0.770 | 
| 10 | oracle | mnm_rss_shared | 10 | 187 | 200 | 28 | 520 | 0.935 | 
| 10 | flash | mnm_shared | 10 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 10 | 198 | 200 | 0 | 0 | 0.990 | 
valid = aggregate(valid ~ n_traits + resid_method + method + L, res.prior.size, sum)
total = aggregate(total ~ n_traits + resid_method + method + L, res.prior.size, sum)
fdr = merge(valid, total, by = c( 'n_traits' , 'resid_method' , 'method', 'L'))
fdr$fdr = round((fdr$total - fdr$valid)/fdr$total,3)
fdr = fdr[order(fdr$n_traits, fdr$L, fdr$method),]
rownames(fdr) = NULL
knitr::kable(fdr) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | valid | total | fdr | 
|---|---|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 49 | 188 | 0.739 | 
| 5 | identity | mnm_rss_shared | 1 | 192 | 200 | 0.040 | 
| 5 | null | mnm_rss_shared | 1 | 168 | 200 | 0.160 | 
| 5 | oracle | mnm_rss_shared | 1 | 191 | 200 | 0.045 | 
| 5 | flash | mnm_shared | 1 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 1 | 195 | 200 | 0.025 | 
| 5 | all | mnm_rss_shared | 2 | 57 | 376 | 0.848 | 
| 5 | identity | mnm_rss_shared | 2 | 197 | 205 | 0.039 | 
| 5 | null | mnm_rss_shared | 2 | 171 | 270 | 0.367 | 
| 5 | oracle | mnm_rss_shared | 2 | 199 | 209 | 0.048 | 
| 5 | flash | mnm_shared | 2 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 2 | 195 | 200 | 0.025 | 
| 5 | all | mnm_rss_shared | 10 | 70 | 1805 | 0.961 | 
| 5 | identity | mnm_rss_shared | 10 | 197 | 205 | 0.039 | 
| 5 | null | mnm_rss_shared | 10 | 173 | 517 | 0.665 | 
| 5 | oracle | mnm_rss_shared | 10 | 197 | 207 | 0.048 | 
| 5 | flash | mnm_shared | 10 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 10 | 195 | 200 | 0.025 | 
| 10 | all | mnm_rss_shared | 1 | 42 | 193 | 0.782 | 
| 10 | identity | mnm_rss_shared | 1 | 187 | 200 | 0.065 | 
| 10 | null | mnm_rss_shared | 1 | 155 | 200 | 0.225 | 
| 10 | oracle | mnm_rss_shared | 1 | 187 | 200 | 0.065 | 
| 10 | flash | mnm_shared | 1 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 1 | 198 | 200 | 0.010 | 
| 10 | all | mnm_rss_shared | 2 | 48 | 384 | 0.875 | 
| 10 | identity | mnm_rss_shared | 2 | 199 | 212 | 0.061 | 
| 10 | null | mnm_rss_shared | 2 | 158 | 297 | 0.468 | 
| 10 | oracle | mnm_rss_shared | 2 | 199 | 212 | 0.061 | 
| 10 | flash | mnm_shared | 2 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 2 | 198 | 200 | 0.010 | 
| 10 | all | mnm_rss_shared | 10 | 50 | 1927 | 0.974 | 
| 10 | identity | mnm_rss_shared | 10 | 205 | 218 | 0.060 | 
| 10 | null | mnm_rss_shared | 10 | 166 | 888 | 0.813 | 
| 10 | oracle | mnm_rss_shared | 10 | 202 | 215 | 0.060 | 
| 10 | flash | mnm_shared | 10 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 10 | 198 | 200 | 0.010 | 
elbo_converged = aggregate(converged~n_traits + resid_method + method + L, res.prior.size, mean)
elbo_converged = elbo_converged[which(elbo_converged$L!=1),]
elbo_converged = elbo_converged[order(elbo_converged$n_traits),]
rownames(elbo_converged) = NULL
knitr::kable(elbo_converged) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24), background = "wheat")
| n_traits | resid_method | method | L | converged | 
|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 2 | 1.000 | 
| 5 | identity | mnm_rss_shared | 2 | 0.990 | 
| 5 | null | mnm_rss_shared | 2 | 1.000 | 
| 5 | oracle | mnm_rss_shared | 2 | 0.965 | 
| 5 | flash | mnm_shared | 2 | 0.955 | 
| 5 | oracle | mnm_shared | 2 | 0.930 | 
| 5 | all | mnm_rss_shared | 10 | 0.955 | 
| 5 | identity | mnm_rss_shared | 10 | 0.980 | 
| 5 | null | mnm_rss_shared | 10 | 0.900 | 
| 5 | oracle | mnm_rss_shared | 10 | 0.945 | 
| 5 | flash | mnm_shared | 10 | 0.955 | 
| 5 | oracle | mnm_shared | 10 | 0.930 | 
| 10 | all | mnm_rss_shared | 2 | 0.990 | 
| 10 | identity | mnm_rss_shared | 2 | 0.980 | 
| 10 | null | mnm_rss_shared | 2 | 0.985 | 
| 10 | oracle | mnm_rss_shared | 2 | 0.985 | 
| 10 | flash | mnm_shared | 2 | 0.915 | 
| 10 | oracle | mnm_shared | 2 | 0.905 | 
| 10 | all | mnm_rss_shared | 10 | 0.945 | 
| 10 | identity | mnm_rss_shared | 10 | 0.955 | 
| 10 | null | mnm_rss_shared | 10 | 0.905 | 
| 10 | oracle | mnm_rss_shared | 10 | 0.955 | 
| 10 | flash | mnm_shared | 10 | 0.915 | 
| 10 | oracle | mnm_shared | 10 | 0.905 | 
purity = aggregate(purity~n_traits + resid_method + method + L, res.prior.oracle, mean)
purity = purity[order(purity$n_traits, purity$L),]
rownames(purity) = NULL
knitr::kable(purity) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | purity | 
|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 0.9403463 | 
| 5 | identity | mnm_rss_shared | 1 | 0.9966379 | 
| 5 | null | mnm_rss_shared | 1 | 0.9868357 | 
| 5 | oracle | mnm_rss_shared | 1 | 0.9969791 | 
| 5 | flash | mnm_shared | 1 | 0.9941027 | 
| 5 | oracle | mnm_shared | 1 | 0.9965768 | 
| 5 | all | mnm_rss_shared | 2 | 0.9923665 | 
| 5 | identity | mnm_rss_shared | 2 | 0.9966379 | 
| 5 | null | mnm_rss_shared | 2 | 0.9860790 | 
| 5 | oracle | mnm_rss_shared | 2 | 0.9969791 | 
| 5 | flash | mnm_shared | 2 | 0.9941027 | 
| 5 | oracle | mnm_shared | 2 | 0.9965768 | 
| 5 | all | mnm_rss_shared | 10 | 0.9999161 | 
| 5 | identity | mnm_rss_shared | 10 | 0.9966379 | 
| 5 | null | mnm_rss_shared | 10 | 0.9888716 | 
| 5 | oracle | mnm_rss_shared | 10 | 0.9969791 | 
| 5 | flash | mnm_shared | 10 | 0.9941027 | 
| 5 | oracle | mnm_shared | 10 | 0.9965768 | 
| 10 | all | mnm_rss_shared | 1 | 0.9394543 | 
| 10 | identity | mnm_rss_shared | 1 | 0.9987209 | 
| 10 | null | mnm_rss_shared | 1 | 0.9952346 | 
| 10 | oracle | mnm_rss_shared | 1 | 0.9987721 | 
| 10 | flash | mnm_shared | 1 | 0.9965968 | 
| 10 | oracle | mnm_shared | 1 | 0.9986715 | 
| 10 | all | mnm_rss_shared | 2 | 0.9978775 | 
| 10 | identity | mnm_rss_shared | 2 | 0.9987209 | 
| 10 | null | mnm_rss_shared | 2 | 0.9919765 | 
| 10 | oracle | mnm_rss_shared | 2 | 0.9987721 | 
| 10 | flash | mnm_shared | 2 | 0.9965968 | 
| 10 | oracle | mnm_shared | 2 | 0.9986715 | 
| 10 | all | mnm_rss_shared | 10 | 1.0000000 | 
| 10 | identity | mnm_rss_shared | 10 | 0.9987209 | 
| 10 | null | mnm_rss_shared | 10 | 0.9936072 | 
| 10 | oracle | mnm_rss_shared | 10 | 0.9987721 | 
| 10 | flash | mnm_shared | 10 | 0.9965968 | 
| 10 | oracle | mnm_shared | 10 | 0.9986715 | 
total_true_included = aggregate(total_true_included ~ n_traits + resid_method + method + L, res.prior.oracle, sum)
total_true = aggregate(total_true ~  n_traits + resid_method + method + L, res.prior.oracle, sum)
cs_overlap = aggregate(overlap_cs ~  n_traits + resid_method + method + L, res.prior.oracle, sum)
snp_overlap = aggregate(overlap_var ~  n_traits + resid_method + method + L, res.prior.oracle, sum)
power = merge(total_true_included, total_true, by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power = merge(power, cs_overlap,  by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power = merge(power, snp_overlap,  by = c( 'n_traits' , 'resid_method' , 'method' , 'L'))
power$power = round(power$total_true_included/power$total_true,3)
power$overlap_cs = round(power$overlap_cs, 3)
power$overlap_var = round(power$overlap_var, 3)
power = power[order(power$n_traits, power$L, power$method),]
rownames(power) = NULL
knitr::kable(power) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | total_true_included | total_true | overlap_cs | overlap_var | power | 
|---|---|---|---|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 39 | 200 | 0 | 0 | 0.195 | 
| 5 | identity | mnm_rss_shared | 1 | 191 | 200 | 0 | 0 | 0.955 | 
| 5 | null | mnm_rss_shared | 1 | 162 | 200 | 0 | 0 | 0.810 | 
| 5 | oracle | mnm_rss_shared | 1 | 190 | 200 | 0 | 0 | 0.950 | 
| 5 | flash | mnm_shared | 1 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 1 | 195 | 200 | 0 | 0 | 0.975 | 
| 5 | all | mnm_rss_shared | 2 | 41 | 200 | 0 | 0 | 0.205 | 
| 5 | identity | mnm_rss_shared | 2 | 191 | 200 | 0 | 0 | 0.955 | 
| 5 | null | mnm_rss_shared | 2 | 165 | 200 | 0 | 0 | 0.825 | 
| 5 | oracle | mnm_rss_shared | 2 | 190 | 200 | 0 | 0 | 0.950 | 
| 5 | flash | mnm_shared | 2 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 2 | 195 | 200 | 0 | 0 | 0.975 | 
| 5 | all | mnm_rss_shared | 10 | 58 | 200 | 0 | 0 | 0.290 | 
| 5 | identity | mnm_rss_shared | 10 | 191 | 200 | 0 | 0 | 0.955 | 
| 5 | null | mnm_rss_shared | 10 | 165 | 200 | 1 | 1 | 0.825 | 
| 5 | oracle | mnm_rss_shared | 10 | 190 | 200 | 0 | 0 | 0.950 | 
| 5 | flash | mnm_shared | 10 | 198 | 200 | 0 | 0 | 0.990 | 
| 5 | oracle | mnm_shared | 10 | 195 | 200 | 0 | 0 | 0.975 | 
| 10 | all | mnm_rss_shared | 1 | 38 | 200 | 0 | 0 | 0.190 | 
| 10 | identity | mnm_rss_shared | 1 | 186 | 200 | 0 | 0 | 0.930 | 
| 10 | null | mnm_rss_shared | 1 | 157 | 200 | 0 | 0 | 0.785 | 
| 10 | oracle | mnm_rss_shared | 1 | 186 | 200 | 0 | 0 | 0.930 | 
| 10 | flash | mnm_shared | 1 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 1 | 198 | 200 | 0 | 0 | 0.990 | 
| 10 | all | mnm_rss_shared | 2 | 43 | 200 | 0 | 0 | 0.215 | 
| 10 | identity | mnm_rss_shared | 2 | 186 | 200 | 0 | 0 | 0.930 | 
| 10 | null | mnm_rss_shared | 2 | 156 | 200 | 0 | 0 | 0.780 | 
| 10 | oracle | mnm_rss_shared | 2 | 186 | 200 | 0 | 0 | 0.930 | 
| 10 | flash | mnm_shared | 2 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 2 | 198 | 200 | 0 | 0 | 0.990 | 
| 10 | all | mnm_rss_shared | 10 | 46 | 200 | 0 | 0 | 0.230 | 
| 10 | identity | mnm_rss_shared | 10 | 186 | 200 | 0 | 0 | 0.930 | 
| 10 | null | mnm_rss_shared | 10 | 155 | 200 | 0 | 0 | 0.775 | 
| 10 | oracle | mnm_rss_shared | 10 | 186 | 200 | 0 | 0 | 0.930 | 
| 10 | flash | mnm_shared | 10 | 200 | 200 | 0 | 0 | 1.000 | 
| 10 | oracle | mnm_shared | 10 | 198 | 200 | 0 | 0 | 0.990 | 
valid = aggregate(valid ~ n_traits + resid_method + method + L, res.prior.oracle, sum)
total = aggregate(total ~ n_traits + resid_method + method + L, res.prior.oracle, sum)
fdr = merge(valid, total, by = c( 'n_traits' , 'resid_method' , 'method', 'L'))
fdr$fdr = round((fdr$total - fdr$valid)/fdr$total,3)
fdr = fdr[order(fdr$n_traits, fdr$L, fdr$method),]
rownames(fdr) = NULL
knitr::kable(fdr) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24, 31:36), background = "wheat")
| n_traits | resid_method | method | L | valid | total | fdr | 
|---|---|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 1 | 39 | 191 | 0.796 | 
| 5 | identity | mnm_rss_shared | 1 | 191 | 200 | 0.045 | 
| 5 | null | mnm_rss_shared | 1 | 162 | 199 | 0.186 | 
| 5 | oracle | mnm_rss_shared | 1 | 190 | 200 | 0.050 | 
| 5 | flash | mnm_shared | 1 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 1 | 195 | 200 | 0.025 | 
| 5 | all | mnm_rss_shared | 2 | 41 | 382 | 0.893 | 
| 5 | identity | mnm_rss_shared | 2 | 191 | 200 | 0.045 | 
| 5 | null | mnm_rss_shared | 2 | 165 | 284 | 0.419 | 
| 5 | oracle | mnm_rss_shared | 2 | 190 | 200 | 0.050 | 
| 5 | flash | mnm_shared | 2 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 2 | 195 | 200 | 0.025 | 
| 5 | all | mnm_rss_shared | 10 | 58 | 1850 | 0.969 | 
| 5 | identity | mnm_rss_shared | 10 | 191 | 200 | 0.045 | 
| 5 | null | mnm_rss_shared | 10 | 165 | 544 | 0.697 | 
| 5 | oracle | mnm_rss_shared | 10 | 190 | 200 | 0.050 | 
| 5 | flash | mnm_shared | 10 | 198 | 200 | 0.010 | 
| 5 | oracle | mnm_shared | 10 | 195 | 200 | 0.025 | 
| 10 | all | mnm_rss_shared | 1 | 38 | 190 | 0.800 | 
| 10 | identity | mnm_rss_shared | 1 | 186 | 200 | 0.070 | 
| 10 | null | mnm_rss_shared | 1 | 157 | 200 | 0.215 | 
| 10 | oracle | mnm_rss_shared | 1 | 186 | 200 | 0.070 | 
| 10 | flash | mnm_shared | 1 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 1 | 198 | 200 | 0.010 | 
| 10 | all | mnm_rss_shared | 2 | 43 | 393 | 0.891 | 
| 10 | identity | mnm_rss_shared | 2 | 186 | 200 | 0.070 | 
| 10 | null | mnm_rss_shared | 2 | 156 | 296 | 0.473 | 
| 10 | oracle | mnm_rss_shared | 2 | 186 | 200 | 0.070 | 
| 10 | flash | mnm_shared | 2 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 2 | 198 | 200 | 0.010 | 
| 10 | all | mnm_rss_shared | 10 | 46 | 1929 | 0.976 | 
| 10 | identity | mnm_rss_shared | 10 | 186 | 200 | 0.070 | 
| 10 | null | mnm_rss_shared | 10 | 155 | 845 | 0.817 | 
| 10 | oracle | mnm_rss_shared | 10 | 186 | 200 | 0.070 | 
| 10 | flash | mnm_shared | 10 | 200 | 200 | 0.000 | 
| 10 | oracle | mnm_shared | 10 | 198 | 200 | 0.010 | 
elbo_converged = aggregate(converged~n_traits + resid_method + method + L, res.prior.oracle, mean)
elbo_converged = elbo_converged[which(elbo_converged$L!=1),]
elbo_converged = elbo_converged[order(elbo_converged$n_traits),]
rownames(elbo_converged) = NULL
knitr::kable(elbo_converged) %>% kable_styling(full_width = F) %>%
  row_spec(c(7:12, 19:24), background = "wheat")
| n_traits | resid_method | method | L | converged | 
|---|---|---|---|---|
| 5 | all | mnm_rss_shared | 2 | 1.000 | 
| 5 | identity | mnm_rss_shared | 2 | 0.990 | 
| 5 | null | mnm_rss_shared | 2 | 0.990 | 
| 5 | oracle | mnm_rss_shared | 2 | 0.975 | 
| 5 | flash | mnm_shared | 2 | 0.955 | 
| 5 | oracle | mnm_shared | 2 | 0.930 | 
| 5 | all | mnm_rss_shared | 10 | 0.860 | 
| 5 | identity | mnm_rss_shared | 10 | 0.990 | 
| 5 | null | mnm_rss_shared | 10 | 0.895 | 
| 5 | oracle | mnm_rss_shared | 10 | 0.975 | 
| 5 | flash | mnm_shared | 10 | 0.955 | 
| 5 | oracle | mnm_shared | 10 | 0.930 | 
| 10 | all | mnm_rss_shared | 2 | 1.000 | 
| 10 | identity | mnm_rss_shared | 2 | 0.980 | 
| 10 | null | mnm_rss_shared | 2 | 0.985 | 
| 10 | oracle | mnm_rss_shared | 2 | 0.980 | 
| 10 | flash | mnm_shared | 2 | 0.915 | 
| 10 | oracle | mnm_shared | 2 | 0.905 | 
| 10 | all | mnm_rss_shared | 10 | 0.865 | 
| 10 | identity | mnm_rss_shared | 10 | 0.980 | 
| 10 | null | mnm_rss_shared | 10 | 0.870 | 
| 10 | oracle | mnm_rss_shared | 10 | 0.980 | 
| 10 | flash | mnm_shared | 10 | 0.915 | 
| 10 | oracle | mnm_shared | 10 | 0.905 | 
sessionInfo()
R version 3.5.1 (2018-07-02)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: Scientific Linux 7.4 (Nitrogen)
Matrix products: default
BLAS/LAPACK: /software/openblas-0.2.19-el7-x86_64/lib/libopenblas_haswellp-r0.2.19.so
locale:
 [1] LC_CTYPE=en_US.UTF-8       LC_NUMERIC=C              
 [3] LC_TIME=en_US.UTF-8        LC_COLLATE=en_US.UTF-8    
 [5] LC_MONETARY=en_US.UTF-8    LC_MESSAGES=en_US.UTF-8   
 [7] LC_PAPER=en_US.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C            
[11] LC_MEASUREMENT=en_US.UTF-8 LC_IDENTIFICATION=C       
attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     
other attached packages:
[1] knitr_1.20       kableExtra_1.1.0 dplyr_0.8.0.1   
loaded via a namespace (and not attached):
 [1] Rcpp_1.0.3        highr_0.7         pillar_1.4.3     
 [4] compiler_3.5.1    later_0.7.5       git2r_0.26.1     
 [7] workflowr_1.6.0   tools_3.5.1       digest_0.6.25    
[10] viridisLite_0.3.0 evaluate_0.12     tibble_2.1.3     
[13] lifecycle_0.1.0   pkgconfig_2.0.3   rlang_0.4.4      
[16] rstudioapi_0.10   yaml_2.2.0        stringr_1.4.0    
[19] httr_1.3.1        xml2_1.2.0        fs_1.3.1         
[22] vctrs_0.2.3       hms_0.5.3         webshot_0.5.1    
[25] rprojroot_1.3-2   tidyselect_0.2.5  glue_1.3.1       
[28] R6_2.4.1          rmarkdown_1.10    purrr_0.3.2      
[31] readr_1.3.1       magrittr_1.5      whisker_0.3-2    
[34] backports_1.1.5   scales_1.1.0      promises_1.0.1   
[37] htmltools_0.3.6   assertthat_0.2.1  rvest_0.3.2      
[40] colorspace_1.4-1  httpuv_1.4.5      stringi_1.4.3    
[43] munsell_0.5.0     crayon_1.3.4