Last updated: 2018-10-06
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Prioritization results are summarized by the following table.
P1: posterior probability that at least one SNP within 100 kb of the transcribed region of a given pathway gene (defined by Chr., Start and End columns) has non-zero effect on the trait of interest;
H-distance: the physical distance, in base pair, between a given pathway gene and its nearest GWAS hit;
Nearest hit: the nearest GWAS hit to a given pathway gene, reported in the corresponding GWAS publication.
The “Inf” values in column H-distance indicate that there is no GWAS hit on the same chromosome as the pathway gene.
Differences between Baseline P1 and Enrichment P1 reflect the influence of enrichment on genetic associations, which can help identify putatively trait-associated genes.
Gene | Chr. | Start | End | Baseline P1 | Enrichment P1 | H-distance | Nearest hit |
---|---|---|---|---|---|---|---|
IL1RAP | 3 | 190231840 | 190374986 | 0.1211674 | 0.6468948 | 140534381 | rs9836291 |
THPO | 3 | 184089773 | 184095932 | 0.1019414 | 0.5669696 | 134392314 | rs9836291 |
TNFSF10 | 3 | 172223298 | 172241297 | 0.0791355 | 0.4918500 | 122525839 | rs9836291 |
IL12A | 3 | 159706623 | 159713806 | 0.1243601 | 0.6128442 | 110009164 | rs9836291 |
IL20RB | 3 | 136676707 | 136729927 | 0.0579184 | 0.3822051 | 86979248 | rs9836291 |
VEGFC | 4 | 177604691 | 177713895 | 0.0822718 | 0.5020834 | 54443072 | rs7657746 |
PDGFA | 7 | 536895 | 559481 | 0.0000000 | 0.0000000 | 49744980 | rs1456896 |
IL25 | 14 | 23842018 | 23845612 | 0.0765771 | 0.4564737 | 45426172 | rs10142466 |
PDGFC | 4 | 157682763 | 157892546 | 0.1231038 | 0.5964468 | 34521144 | rs7657746 |
IL17A | 6 | 52051185 | 52055436 | 0.1080164 | 0.5631072 | 31393840 | rs2328546 |
IL7 | 8 | 79645007 | 79717758 | 0.0678664 | 0.4309576 | 30515765 | rs7011507 |
CCL21 | 9 | 34709002 | 34710147 | 0.0907260 | 0.4857704 | 29727400 | rs75900472 |
CCL19 | 9 | 34689567 | 34691274 | 0.0846582 | 0.4622274 | 29707965 | rs75900472 |
CCL27 | 9 | 34661893 | 34662689 | 0.0803038 | 0.4628825 | 29680291 | rs75900472 |
IL11RA | 9 | 34652182 | 34661884 | 0.0863002 | 0.4877774 | 29670580 | rs75900472 |
CNTFR | 9 | 34551430 | 34590138 | 0.0636690 | 0.4126994 | 29569828 | rs75900472 |
CCL17 | 16 | 57438679 | 57449974 | 0.0907944 | 0.5039084 | 28564907 | rs11641016 |
CX3CL1 | 16 | 57406414 | 57418956 | 0.0836649 | 0.4730927 | 28541372 | rs62037363 |
CCL22 | 16 | 57392695 | 57400102 | 0.0799879 | 0.4574066 | 28527653 | rs62037363 |
CXCL16 | 17 | 4636828 | 4643223 | 0.2174982 | 0.5319488 | 27927324 | rs9889296 |
IL6 | 7 | 22766766 | 22771621 | 0.2709954 | 0.8711529 | 27532840 | rs1456896 |
TNFRSF21 | 6 | 47199268 | 47277680 | 0.1386729 | 0.6508431 | 26541923 | rs2328546 |
TNFSF12 | 17 | 7452375 | 7461207 | 0.0727418 | 0.4599756 | 25109340 | rs9889296 |
TNFSF13 | 17 | 7461609 | 7464925 | 0.0693347 | 0.4439229 | 25105622 | rs9889296 |
BMP2 | 20 | 6748745 | 6760910 | 0.1324832 | 0.6521074 | 24088607 | rs4243971 |
CXCR4 | 2 | 136871919 | 136875725 | 0.0458274 | 0.3150303 | 23918283 | rs4664304 |
CCL26 | 7 | 75398842 | 75419064 | 0.0558492 | 0.3430393 | 23331315 | rs2395022 |
CCL24 | 7 | 75441114 | 75443033 | 0.0382205 | 0.2492447 | 23307346 | rs2395022 |
VEGFA | 6 | 43737946 | 43754224 | 0.7308307 | 0.9770565 | 23080601 | rs2328546 |
MPL | 1 | 43803475 | 43820135 | 0.1251848 | 0.5283171 | 21103124 | rs34920465 |
BMPR1B | 4 | 95679128 | 96079601 | 0.1905497 | 0.7920176 | 20822593 | rs2457996 |
KITLG | 12 | 88886570 | 88974250 | 0.0706986 | 0.4438487 | 20382734 | rs12318183 |
IL15 | 4 | 142557749 | 142655140 | 0.0599351 | 0.3985980 | 19396130 | rs7657746 |
INHBB | 2 | 121103719 | 121109383 | 0.0418954 | 0.2894233 | 18119440 | rs1420098 |
KDR | 4 | 55944426 | 55991762 | 0.2876756 | 0.8112923 | 17619390 | rs6856616 |
HGF | 7 | 81331444 | 81399452 | 0.1780008 | 0.6715877 | 17350927 | rs2395022 |
KIT | 4 | 55524095 | 55606881 | 0.1593271 | 0.6733895 | 17199059 | rs6856616 |
PDGFRA | 4 | 55095264 | 55164412 | 0.0564182 | 0.3694700 | 16770228 | rs6856616 |
IFNE | 9 | 21480838 | 21482312 | 0.0433841 | 0.3110485 | 16499236 | rs75900472 |
IFNA1 | 9 | 21440440 | 21441315 | 0.0455388 | 0.3175837 | 16458838 | rs75900472 |
IFNA8 | 9 | 21409146 | 21410184 | 0.0430719 | 0.3013206 | 16427544 | rs75900472 |
IFNA2 | 9 | 21384254 | 21385396 | 0.0468888 | 0.3217468 | 16402652 | rs75900472 |
IFNA13 | 9 | 21367371 | 21368075 | 0.0458046 | 0.3149171 | 16385769 | rs75900472 |
IFNA6 | 9 | 21350317 | 21350886 | 0.0483434 | 0.3299738 | 16368715 | rs75900472 |
IFNA5 | 9 | 21304613 | 21305312 | 0.0440514 | 0.3034910 | 16323011 | rs75900472 |
IFNA14 | 9 | 21239201 | 21239978 | 0.0406441 | 0.2856126 | 16257599 | rs75900472 |
IFNA17 | 9 | 21227242 | 21228221 | 0.0635838 | 0.3613240 | 16245640 | rs75900472 |
IFNA16 | 9 | 21216372 | 21217310 | 0.0691056 | 0.3772800 | 16234770 | rs75900472 |
IFNA10 | 9 | 21206180 | 21207142 | 0.0735686 | 0.3907294 | 16224578 | rs75900472 |
IFNA7 | 9 | 21201468 | 21202204 | 0.0715706 | 0.3798713 | 16219866 | rs75900472 |
IFNA4 | 9 | 21186617 | 21187598 | 0.1179639 | 0.4736982 | 16205015 | rs75900472 |
IFNA21 | 9 | 21165636 | 21166659 | 0.1670687 | 0.5490369 | 16184034 | rs75900472 |
IFNW1 | 9 | 21140631 | 21142144 | 0.2404248 | 0.6589534 | 16159029 | rs75900472 |
IFNB1 | 9 | 21077104 | 21077943 | 0.2576792 | 0.7071867 | 16095502 | rs75900472 |
TNFRSF13B | 17 | 16842398 | 16875402 | 0.0912251 | 0.5254070 | 15695145 | rs9889296 |
IL5RA | 3 | 3111401 | 3152058 | 0.1768972 | 0.7280314 | 15589744 | rs11708026 |
IL6ST | 5 | 55230923 | 55290821 | 0.0881705 | 0.4962377 | 14831827 | rs6880778 |
CSF3R | 1 | 36931644 | 36948915 | 0.1071012 | 0.5141904 | 14231293 | rs34920465 |
TSLP | 5 | 110407390 | 110413722 | 0.0559340 | 0.3794414 | 14154587 | rs1363907 |
CCR4 | 3 | 32993066 | 32996403 | 0.0426039 | 0.3098669 | 13461009 | rs113010081 |
EGF | 4 | 110834040 | 110934118 | 0.0929935 | 0.5519322 | 12227501 | rs7657746 |
ACVR2A | 2 | 148602570 | 148688393 | 0.1764827 | 0.5699544 | 12105615 | rs4664304 |
TGFBR2 | 3 | 30647994 | 30735634 | 0.3635260 | 0.8781533 | 11906192 | rs11708026 |
TGFB2 | 1 | 218518676 | 218617961 | 0.1919946 | 0.6991740 | 11574708 | rs3024493 |
LEP | 7 | 127881331 | 127897682 | 0.1066037 | 0.5552055 | 10986168 | rs38911 |
LTB | 6 | 31548335 | 31550202 | 0.0000000 | 0.0000000 | 10890990 | rs2328546 |
TNF | 6 | 31543350 | 31546112 | 0.0000000 | 0.0000000 | 10886005 | rs2328546 |
LTA | 6 | 31539876 | 31542098 | 0.0000000 | 0.0000000 | 10882531 | rs2328546 |
IL1B | 2 | 113587337 | 113594356 | 0.1134628 | 0.5431825 | 10603058 | rs1420098 |
IL1A | 2 | 113531492 | 113542971 | 0.1045134 | 0.5031943 | 10547213 | rs1420098 |
INHBE | 12 | 57849096 | 57851791 | 0.0769541 | 0.6765758 | 9640728 | rs11168249 |
INHBC | 12 | 57828543 | 57844609 | 0.0781963 | 0.6810688 | 9620175 | rs11168249 |
CXCL12 | 10 | 44865605 | 44880545 | 0.1475955 | 0.7059944 | 9399420 | rs34779708 |
CSF1 | 1 | 110453233 | 110472355 | 0.5189795 | 0.9252968 | 8987179 | rs11583043 |
TNFSF13B | 13 | 108921977 | 108960832 | 0.1172489 | 0.5949326 | 8885559 | rs9557207 |
TNFRSF12A | 16 | 3070313 | 3072384 | 0.0537591 | 0.3277571 | 8632267 | rs11641184 |
INHBA | 7 | 41728601 | 41742706 | 0.0605288 | 0.4012280 | 8561755 | rs1456896 |
IL23A | 12 | 56732663 | 56734194 | 0.0344458 | 0.2525439 | 8524295 | rs11168249 |
AMH | 19 | 2249113 | 2252072 | 0.0173109 | 0.1379221 | 8273109 | rs35164067 |
TGFB1 | 19 | 41836812 | 41859831 | 0.0600081 | 0.3715527 | 8105261 | rs17694108 |
TGFBR1 | 9 | 101867412 | 101916474 | 0.0583177 | 0.3881668 | 7938996 | rs4743820 |
ACVR2B | 3 | 38495790 | 38534633 | 0.0732051 | 0.4681813 | 7922779 | rs113010081 |
IL12RB1 | 19 | 18170371 | 18197697 | 0.1216733 | 0.5346174 | 7645190 | rs35164067 |
TNFRSF11A | 18 | 59992548 | 60053504 | 0.1715361 | 0.7329361 | 7483847 | rs17207042 |
CX3CR1 | 3 | 39304985 | 39323226 | 0.1122120 | 0.5460035 | 7134186 | rs113010081 |
CCR8 | 3 | 39371197 | 39375171 | 0.1031292 | 0.5066400 | 7082241 | rs113010081 |
NGFR | 17 | 47572655 | 47592382 | 0.0367319 | 0.2707256 | 7058454 | rs744166 |
IL18 | 11 | 112013976 | 112034840 | 0.1467513 | 0.6134279 | 6730760 | rs3922 |
TNFRSF11B | 8 | 119935796 | 119964383 | 0.0845439 | 0.5172860 | 6571754 | rs10956252 |
EDAR | 2 | 109510927 | 109605828 | 0.0694400 | 0.4510725 | 6526648 | rs1420098 |
TNFRSF1A | 12 | 6437923 | 6451283 | 0.0977763 | 0.4034113 | 6197560 | rs11054935 |
LTBR | 12 | 6493357 | 6500734 | 0.1446654 | 0.5549788 | 6148109 | rs11054935 |
CD27 | 12 | 6554051 | 6560884 | 0.1519416 | 0.6015973 | 6087959 | rs11054935 |
IFNL1 | 19 | 39786965 | 39789312 | 0.0375034 | 0.2757856 | 6055414 | rs17694108 |
IFNL2 | 19 | 39759157 | 39760732 | 0.0359448 | 0.2658592 | 6027606 | rs17694108 |
IFNL3 | 19 | 39734272 | 39735611 | 0.0332638 | 0.2481781 | 6002721 | rs17694108 |
IFNAR2 | 21 | 34602231 | 34636827 | 0.1680514 | 0.6422069 | 5829917 | rs2836883 |
BMPR1A | 10 | 88516396 | 88684945 | 0.1133331 | 0.5751648 | 5817299 | rs11187157 |
IL10RB | 21 | 34638672 | 34669520 | 0.1944269 | 0.6413052 | 5797224 | rs2836883 |
IFNAR1 | 21 | 34697214 | 34732129 | 0.2137619 | 0.7057553 | 5734615 | rs2836883 |
IFNGR2 | 21 | 34775202 | 34809828 | 0.2079020 | 0.6836598 | 5656916 | rs2836883 |
AMHR2 | 12 | 53817639 | 53825318 | 0.1323745 | 0.5572424 | 5609271 | rs11168249 |
FLT3LG | 19 | 49977466 | 49989488 | 0.0445039 | 0.3110603 | 5390726 | rs17771967 |
EGFR | 7 | 55086725 | 55275031 | 0.2322406 | 0.7886587 | 4782264 | rs1456896 |
IL17RA | 22 | 17565851 | 17596584 | 0.0674306 | 0.4299165 | 4332013 | rs2266961 |
TNFRSF10B | 8 | 22877646 | 22926700 | 0.1090846 | 0.5720964 | 4300854 | rs17057051 |
TNFRSF10C | 8 | 22960327 | 22974950 | 0.0605918 | 0.3707607 | 4252604 | rs17057051 |
TNFRSF10D | 8 | 22993101 | 23021540 | 0.0680886 | 0.4103524 | 4206014 | rs17057051 |
IL17RB | 3 | 53880577 | 53899827 | 0.1309921 | 0.6155632 | 4183118 | rs9836291 |
TNFRSF10A | 8 | 23048970 | 23082680 | 0.0844998 | 0.4929860 | 4144874 | rs17057051 |
ACVR1B | 12 | 52345451 | 52390863 | 0.4747861 | 0.8997003 | 4137083 | rs11168249 |
TNFRSF1B | 1 | 12227060 | 12269277 | 0.1234985 | 0.5143607 | 4076422 | rs72634258 |
ACKR3 | 2 | 237478380 | 237490997 | 0.0455604 | 0.3232141 | 4072742 | rs4676410 |
GH1 | 17 | 61994563 | 61996198 | 0.0320263 | 0.2389654 | 4031026 | rs1292053 |
GH2 | 17 | 61957572 | 61959223 | 0.0336894 | 0.2495422 | 3994035 | rs1292053 |
TNFSF9 | 19 | 6531010 | 6535939 | 0.0063833 | 0.0513640 | 3989242 | rs35164067 |
TNFRSF8 | 1 | 12123434 | 12204264 | 0.1545285 | 0.5799452 | 3972796 | rs72634258 |
CD70 | 19 | 6585850 | 6591163 | 0.0319849 | 0.2269298 | 3934018 | rs35164067 |
TNFSF14 | 19 | 6663148 | 6670599 | 0.0699385 | 0.4056353 | 3854582 | rs35164067 |
FAS | 10 | 90750288 | 90775542 | 0.8190555 | 0.9901607 | 3726702 | rs11187157 |
PRLR | 5 | 35048861 | 35230823 | 0.2333031 | 0.7705967 | 3636909 | rs395157 |
TNFSF4 | 1 | 173152870 | 173176471 | 0.1038779 | 0.5008589 | 3633821 | rs6025 |
CXCL13 | 4 | 78432907 | 78532988 | 0.0592353 | 0.4038146 | 3576372 | rs2457996 |
IL9 | 5 | 135227935 | 135231516 | 0.0811753 | 0.4926667 | 3555278 | rs56399423 |
TNFSF18 | 1 | 173010360 | 173020103 | 0.0683219 | 0.4470095 | 3491311 | rs6025 |
TNFRSF19 | 13 | 24144509 | 24250244 | 0.1111778 | 0.6099884 | 3278103 | rs12585310 |
FLT4 | 5 | 180028506 | 180076624 | 0.0349901 | 0.2567228 | 3239936 | rs4976646 |
CXCL14 | 5 | 134906369 | 134914969 | 0.0631346 | 0.4171339 | 3233712 | rs56399423 |
RELT | 11 | 73087405 | 73108519 | 0.0415362 | 0.2911527 | 3191130 | rs11236797 |
FASLG | 1 | 172628185 | 172636013 | 0.0582318 | 0.3658622 | 3109136 | rs6025 |
IL7R | 5 | 35856991 | 35876924 | 0.1735805 | 0.6594925 | 2990808 | rs395157 |
CCL28 | 5 | 43381600 | 43412488 | 0.0784331 | 0.4474678 | 2982504 | rs6880778 |
GDF5 | 20 | 34021149 | 34026027 | 0.0945637 | 0.4685037 | 2672399 | rs6058869 |
TNFRSF13C | 22 | 42321036 | 42322821 | 0.0447163 | 0.3208326 | 2660207 | rs2143178 |
CCL25 | 19 | 8117646 | 8127547 | 0.0552611 | 0.3701929 | 2397634 | rs35164067 |
CSF2RB | 22 | 37309675 | 37336481 | 0.1182838 | 0.6104822 | 2324348 | rs2143178 |
PLEKHO2 | 15 | 65134082 | 65160201 | 0.0591530 | 0.3957037 | 2282395 | rs17293632 |
TNFSF11 | 13 | 43136872 | 43182149 | 0.3474281 | 0.8218047 | 2122895 | rs941823 |
IL2RB | 22 | 37521878 | 37545962 | 0.1163734 | 0.6110001 | 2114867 | rs2143178 |
CXCL11 | 4 | 76954835 | 76957350 | 0.3990792 | 0.7493784 | 2098300 | rs2457996 |
CXCL10 | 4 | 76942269 | 76944689 | 0.4043712 | 0.7571826 | 2085734 | rs2457996 |
CCL4L1 | 17 | 34640034 | 34641841 | 0.0000000 | 0.0000000 | 2069487 | rs9889296 |
CXCL9 | 4 | 76922623 | 76928641 | 0.4066394 | 0.7633795 | 2066088 | rs2457996 |
ACVR1 | 2 | 158592958 | 158732374 | 0.0598678 | 0.3982634 | 2061634 | rs4664304 |
CCL3L1 | 17 | 34623842 | 34625730 | 0.0000000 | 0.0000000 | 2053295 | rs9889296 |
CTF1 | 16 | 30907928 | 30914881 | 0.0325094 | 0.2313714 | 2042886 | rs62037363 |
GHR | 5 | 42423877 | 42721980 | 0.0904185 | 0.5408069 | 2024781 | rs6880778 |
BMP7 | 20 | 55743809 | 55841707 | 0.1235395 | 0.6478522 | 1982602 | rs259964 |
CCL4L2 | 17 | 34538468 | 34540275 | 0.0000000 | 0.0000000 | 1967921 | rs9889296 |
CCL3L3 | 17 | 34522268 | 34524147 | 0.0114141 | 0.0810715 | 1951721 | rs9889296 |
CCL4 | 17 | 34431220 | 34433014 | 0.0570717 | 0.3594238 | 1860673 | rs9889296 |
CCL3 | 17 | 34415602 | 34417506 | 0.0608363 | 0.3805209 | 1845055 | rs9889296 |
CCL18 | 17 | 34391643 | 34398841 | 0.0675162 | 0.4165687 | 1821096 | rs9889296 |
IFNLR1 | 1 | 24480647 | 24513765 | 0.2149151 | 0.7093501 | 1780296 | rs34920465 |
CCL23 | 17 | 34340097 | 34345005 | 0.0741077 | 0.4501048 | 1769550 | rs9889296 |
CCL15 | 17 | 34324618 | 34329084 | 0.0714136 | 0.4425849 | 1754071 | rs9889296 |
IL22RA1 | 1 | 24446261 | 24469775 | 0.2531659 | 0.7362506 | 1745910 | rs34920465 |
CCL14 | 17 | 34310692 | 34313764 | 0.0673749 | 0.4256535 | 1740145 | rs9889296 |
CCL16 | 17 | 34303535 | 34308523 | 0.0677807 | 0.4289023 | 1732988 | rs9889296 |
CLCF1 | 11 | 67131639 | 67141648 | 0.0623595 | 0.4103876 | 1704071 | rs732072 |
PRL | 6 | 22287475 | 22303082 | 0.1053623 | 0.5789627 | 1630130 | rs2328546 |
LEPR | 1 | 65886335 | 66103176 | 0.1374383 | 0.6799863 | 1628192 | rs7547569 |
CCL5 | 17 | 34198495 | 34207377 | 0.0409242 | 0.2956795 | 1627948 | rs9889296 |
TNFRSF25 | 1 | 6521211 | 6526255 | 0.1245952 | 0.5265035 | 1624383 | rs72634258 |
IL17B | 5 | 148753830 | 148758838 | 0.0715071 | 0.4501881 | 1564590 | rs17800987 |
IL4R | 16 | 27325251 | 27376099 | 0.0764718 | 0.4805221 | 1488943 | rs62037363 |
IL21R | 16 | 27413483 | 27463363 | 0.0691281 | 0.4460893 | 1401679 | rs62037363 |
FLT1 | 13 | 28874483 | 29069265 | 0.1061847 | 0.6005390 | 1346136 | rs12585310 |
IL6R | 1 | 154377669 | 154441926 | 0.0971744 | 0.5180839 | 1240944 | rs490608 |
TNFRSF14 | 1 | 2487805 | 2495268 | 0.9811550 | 0.9973123 | 1240311 | rs12103 |
BMPR2 | 2 | 203241050 | 203432474 | 0.0766933 | 0.4707823 | 1159547 | rs3116494 |
FLT3 | 13 | 28577411 | 28674729 | 0.0912741 | 0.5236001 | 1049064 | rs12585310 |
XCL2 | 1 | 168510003 | 168513235 | 0.0665243 | 0.4261377 | 1005814 | rs6025 |
XCL1 | 1 | 168545711 | 168551315 | 0.0739010 | 0.4630186 | 967734 | rs6025 |
EPOR | 19 | 11487881 | 11495018 | 0.0384605 | 0.2804461 | 962700 | rs35164067 |
IL10RA | 11 | 117857106 | 117872198 | 0.2382738 | 0.7648509 | 893402 | rs3922 |
CSF1R | 5 | 149432854 | 149492935 | 0.1497649 | 0.6771708 | 830493 | rs17800987 |
PDGFRB | 5 | 149493402 | 149535422 | 0.7994102 | 0.9818657 | 788006 | rs17800987 |
CCR7 | 17 | 38710021 | 38721736 | 0.0741602 | 0.4119409 | 686276 | rs4795397 |
TGFB3 | 14 | 76424442 | 76448092 | 0.0702246 | 0.4265614 | 682691 | rs1569328 |
IL20RA | 6 | 137321108 | 137366298 | 0.1202230 | 0.6099303 | 592937 | rs6933404 |
CCR9 | 3 | 45927996 | 45944667 | 0.1248371 | 0.5696247 | 512745 | rs113010081 |
IL11 | 19 | 55875757 | 55881814 | 0.0448901 | 0.2696729 | 495543 | rs17771967 |
CXCR6 | 3 | 45984973 | 45989845 | 0.1064024 | 0.5150932 | 467567 | rs113010081 |
IL22RA2 | 6 | 137464957 | 137494785 | 0.1349964 | 0.6150391 | 464450 | rs6933404 |
MET | 7 | 116312459 | 116438440 | 0.0719991 | 0.4468830 | 456723 | rs38911 |
IFNGR1 | 6 | 137518621 | 137540567 | 0.1340636 | 0.6147708 | 418668 | rs6933404 |
XCR1 | 3 | 46062291 | 46068979 | 0.0641791 | 0.3993398 | 388433 | rs113010081 |
IL21 | 4 | 123533783 | 123542211 | 0.2624787 | 0.6868542 | 372164 | rs7657746 |
TNFRSF17 | 16 | 12058964 | 12061925 | 0.1533802 | 0.6080036 | 354313 | rs11641184 |
IL1R2 | 2 | 102608306 | 102644885 | 0.9297641 | 0.9899959 | 339394 | rs1420098 |
IL4 | 5 | 132009373 | 132018368 | 0.0924539 | 0.4432131 | 336716 | rs56399423 |
IL13 | 5 | 131993865 | 131996801 | 0.0766069 | 0.3904895 | 321208 | rs56399423 |
CCR10 | 17 | 40831420 | 40833845 | 0.0352348 | 0.9959315 | 317219 | rs744166 |
LIFR | 5 | 38475065 | 38595507 | 0.0727055 | 0.4439382 | 272225 | rs395157 |
CXCL8 | 4 | 74606223 | 74609433 | 0.0864215 | 0.3692384 | 247102 | rs2457996 |
IL2 | 4 | 123372625 | 123377650 | 0.2592971 | 0.9861382 | 211006 | rs7657746 |
IL3 | 5 | 131396347 | 131398896 | 0.0899994 | 0.5514453 | 208404 | rs55722650 |
CCR1 | 3 | 46243200 | 46249832 | 0.0849921 | 0.3977279 | 207580 | rs113010081 |
IL5 | 5 | 131877136 | 131879214 | 0.2303778 | 1.0000000 | 204479 | rs56399423 |
CSF2 | 5 | 131409485 | 131411859 | 0.0895466 | 0.5486182 | 195441 | rs55722650 |
IL1R1 | 2 | 102770402 | 102796334 | 0.1564947 | 0.7125871 | 187945 | rs1420098 |
CXCL6 | 4 | 74702273 | 74704477 | 0.0623253 | 0.3474871 | 152058 | rs2457996 |
CCR3 | 3 | 46283872 | 46308197 | 0.1566223 | 0.5333797 | 149215 | rs113010081 |
CSF3 | 17 | 38171614 | 38174066 | 0.0421101 | 1.0000000 | 147869 | rs4795397 |
TNFRSF9 | 1 | 7975931 | 8003225 | 0.9982370 | 0.9999410 | 147413 | rs72634258 |
VEGFB | 11 | 64002266 | 64006259 | 0.2299245 | 0.7344686 | 144111 | rs559928 |
IL22 | 12 | 68642025 | 68647281 | 0.2507095 | 0.7387564 | 138189 | rs12318183 |
PF4V1 | 4 | 74719013 | 74720198 | 0.0691617 | 0.3633666 | 136337 | rs2457996 |
CCR6 | 6 | 167525295 | 167552629 | 0.1684129 | 0.9999708 | 135053 | rs444210 |
IL24 | 1 | 207070788 | 207077484 | 0.1481123 | 0.6071227 | 126820 | rs3024493 |
CXCR2 | 2 | 218990013 | 219001976 | 0.9933495 | 0.9985591 | 119687 | rs11677953 |
CXCL1 | 4 | 74735109 | 74736959 | 0.0764784 | 0.3798093 | 119576 | rs2457996 |
CCL1 | 17 | 32687399 | 32690252 | 0.1623449 | 0.7173104 | 116852 | rs9889296 |
CCL13 | 17 | 32683471 | 32685629 | 0.1624732 | 0.7176498 | 112924 | rs9889296 |
CXCL2 | 4 | 74962752 | 74964997 | 0.0407753 | 0.2255811 | 106217 | rs2457996 |
TNFRSF18 | 1 | 1138888 | 1142089 | 0.2667326 | 0.7165407 | 105405 | rs12103 |
EPO | 7 | 100318423 | 100321323 | 0.1795787 | 0.5934971 | 102042 | rs314313 |
TNFRSF4 | 1 | 1146706 | 1149548 | 0.2659588 | 0.7140019 | 97946 | rs12103 |
TNFSF8 | 9 | 117665124 | 117692770 | 0.9284044 | 0.9984673 | 96078 | rs7848647 |
IL20 | 1 | 207039154 | 207042568 | 1.0000000 | 1.0000000 | 95186 | rs3024493 |
IL26 | 12 | 68595129 | 68619571 | 0.2381573 | 0.7243748 | 91293 | rs12318183 |
CXCR1 | 2 | 219027568 | 219031716 | 0.9933811 | 0.9985827 | 89947 | rs11677953 |
OSM | 22 | 30658818 | 30662829 | 0.2216169 | 0.5893573 | 88796 | rs1003342 |
CCL8 | 17 | 32646066 | 32648421 | 0.9994240 | 0.9999519 | 75519 | rs9889296 |
IL12B | 5 | 158741791 | 158757481 | 1.0000000 | 1.0000000 | 70288 | rs56167332 |
LIF | 22 | 30636442 | 30642796 | 0.2482970 | 0.9996446 | 66420 | rs1003342 |
IL15RA | 10 | 5994334 | 6020142 | 0.3203923 | 0.8217118 | 61088 | rs12722515 |
CCR2 | 3 | 46395235 | 46402413 | 0.1522508 | 0.5337070 | 54999 | rs113010081 |
IL18RAP | 2 | 103035254 | 103069025 | 0.9994516 | 0.9998867 | 50975 | rs1420098 |
CXCL3 | 4 | 74902306 | 74904490 | 0.1160103 | 0.4152061 | 45771 | rs2457996 |
IFNG | 12 | 68548550 | 68553521 | 1.0000000 | 1.0000000 | 44714 | rs12318183 |
CCL11 | 17 | 32612687 | 32615199 | 0.9994111 | 0.9999446 | 42140 | rs9889296 |
IL12RB2 | 1 | 67773047 | 67862583 | 1.0000000 | 1.0000000 | 41679 | rs7547569 |
CCR5 | 3 | 46411633 | 46417697 | 0.1561304 | 0.5501440 | 39715 | rs113010081 |
IL19 | 1 | 206972215 | 207016326 | 1.0000000 | 1.0000000 | 28247 | rs3024493 |
CCL7 | 17 | 32597240 | 32599256 | 0.9993994 | 0.9999374 | 26693 | rs9889296 |
PDGFB | 22 | 39619685 | 39640957 | 0.9999985 | 0.9999995 | 19872 | rs2143178 |
CCL20 | 2 | 228678558 | 228682280 | 0.1669462 | 0.5621361 | 18446 | rs111781203 |
CNTF | 11 | 58390146 | 58393206 | 0.2798907 | 0.8752873 | 15481 | rs11229555 |
CCL2 | 17 | 32582296 | 32584222 | 0.9993853 | 0.9999294 | 11749 | rs9889296 |
PF4 | 4 | 74846796 | 74847715 | 0.1426060 | 0.5070800 | 8820 | rs2457996 |
CD40 | 20 | 44746906 | 44758384 | 0.2891589 | 0.6989352 | 6710 | rs6074022 |
IL23R | 1 | 67632169 | 67725662 | 1.0000000 | 1.0000000 | 5706 | rs7547569 |
CXCL5 | 4 | 74861359 | 74864416 | 0.1370021 | 0.4810513 | 4824 | rs2457996 |
PPBP | 4 | 74852156 | 74853907 | 0.1395333 | 0.4927416 | 2628 | rs2457996 |
TNFSF15 | 9 | 117546915 | 117568408 | 1.0000000 | 1.0000000 | 638 | rs7848647 |
IL10 | 1 | 206940948 | 206945839 | 1.0000000 | 1.0000000 | 0 | rs3024493 |
TNFRSF6B | 20 | 62328004 | 62330051 | 0.9999996 | 0.9999995 | 0 | rs6062496 |
IL18R1 | 2 | 102979097 | 103015218 | 0.9994716 | 0.9998906 | 0 | rs1420098 |
OSMR | 5 | 38845960 | 38935743 | 0.6556474 | 0.9759380 | 0 | rs395157 |
IL2RA | 10 | 6052657 | 6104333 | 0.3402194 | 0.8370421 | 0 | rs12722515 |
CXCR5 | 11 | 118754541 | 118766971 | 0.0472994 | 0.3239491 | 0 | rs3922 |
Session info -------------------------------------------------------------
setting value
version R version 3.5.1 (2018-07-02)
system x86_64, darwin15.6.0
ui X11
language (EN)
collate en_US.UTF-8
tz America/Los_Angeles
date 2018-10-06
Packages -----------------------------------------------------------------
package * version date source
assertthat 0.2.0 2017-04-11 CRAN (R 3.5.0)
backports 1.1.2 2017-12-13 CRAN (R 3.5.0)
base * 3.5.1 2018-07-05 local
bindr 0.1.1 2018-03-13 CRAN (R 3.5.0)
bindrcpp * 0.2.2 2018-03-29 CRAN (R 3.5.0)
colorspace 1.3-2 2016-12-14 CRAN (R 3.5.0)
compiler 3.5.1 2018-07-05 local
crayon 1.3.4 2017-09-16 CRAN (R 3.5.0)
datasets * 3.5.1 2018-07-05 local
devtools 1.13.6 2018-06-27 CRAN (R 3.5.0)
digest 0.6.17 2018-09-12 CRAN (R 3.5.1)
dplyr * 0.7.6 2018-06-29 CRAN (R 3.5.1)
evaluate 0.11 2018-07-17 CRAN (R 3.5.0)
git2r 0.23.0 2018-07-17 CRAN (R 3.5.0)
glue 1.3.0 2018-07-17 CRAN (R 3.5.0)
graphics * 3.5.1 2018-07-05 local
grDevices * 3.5.1 2018-07-05 local
highr 0.7 2018-06-09 CRAN (R 3.5.0)
hms 0.4.2 2018-03-10 CRAN (R 3.5.0)
htmltools 0.3.6 2017-04-28 CRAN (R 3.5.0)
httr 1.3.1 2017-08-20 CRAN (R 3.5.0)
kableExtra * 0.9.0 2018-05-21 CRAN (R 3.5.0)
knitr 1.20 2018-02-20 CRAN (R 3.5.0)
magrittr 1.5 2014-11-22 CRAN (R 3.5.0)
memoise 1.1.0 2017-04-21 CRAN (R 3.5.0)
methods * 3.5.1 2018-07-05 local
munsell 0.5.0 2018-06-12 CRAN (R 3.5.0)
pillar 1.3.0 2018-07-14 CRAN (R 3.5.0)
pkgconfig 2.0.2 2018-08-16 CRAN (R 3.5.0)
purrr 0.2.5 2018-05-29 CRAN (R 3.5.0)
R.matlab * 3.6.2 2018-09-27 CRAN (R 3.5.0)
R.methodsS3 1.7.1 2016-02-16 CRAN (R 3.5.0)
R.oo 1.22.0 2018-04-22 CRAN (R 3.5.0)
R.utils 2.7.0 2018-08-27 CRAN (R 3.5.0)
R6 2.3.0 2018-10-04 CRAN (R 3.5.1)
Rcpp 0.12.19 2018-10-01 CRAN (R 3.5.0)
readr 1.1.1 2017-05-16 CRAN (R 3.5.0)
rlang 0.2.2 2018-08-16 CRAN (R 3.5.0)
rmarkdown 1.10 2018-06-11 CRAN (R 3.5.0)
rprojroot 1.3-2 2018-01-03 CRAN (R 3.5.0)
rstudioapi 0.8 2018-10-02 CRAN (R 3.5.0)
rvest 0.3.2 2016-06-17 CRAN (R 3.5.0)
scales 1.0.0 2018-08-09 CRAN (R 3.5.0)
stats * 3.5.1 2018-07-05 local
stringi 1.2.4 2018-07-20 CRAN (R 3.5.0)
stringr 1.3.1 2018-05-10 CRAN (R 3.5.0)
tibble 1.4.2 2018-01-22 CRAN (R 3.5.0)
tidyselect 0.2.4 2018-02-26 CRAN (R 3.5.0)
tools 3.5.1 2018-07-05 local
utils * 3.5.1 2018-07-05 local
viridisLite 0.3.0 2018-02-01 CRAN (R 3.5.0)
whisker 0.3-2 2013-04-28 CRAN (R 3.5.0)
withr 2.1.2 2018-03-15 CRAN (R 3.5.0)
workflowr 1.1.1 2018-07-06 CRAN (R 3.5.0)
xml2 1.2.0 2018-01-24 CRAN (R 3.5.0)
yaml 2.2.0 2018-07-25 CRAN (R 3.5.0)
This reproducible R Markdown analysis was created with workflowr 1.1.1