Last updated: 2022-05-10

Checks: 1 1

Knit directory: apocrine_signature_mdamb453/

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File Version Author Date Message
Rmd 8797971 Steve Pederson 2022-04-27 Start workflowr project.

Introduction

This analysis compares the binding sites of AR, FOXA1, GATA3 and TFAP2B in MDA-MB-453 cells. All ChIP targets were obtained from separate experiments using Vehicle as the reference condition and DHT-treatment as the key response under investigation. Given the mostly cytoplasmic location of AR in Vehicle, the primary comparison will be performed using DHT-treated samples. For all targets, the cistrome is largely conserved across conditions. Analysis using the GRAVI workflow is available here (for those given access)