Last updated: 2023-12-18

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Knit directory: Cardiotoxicity/

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Rmd 74c2dc1 reneeisnowhere 2023-10-30 updated
Rmd d970e84 reneeisnowhere 2023-10-30 adding more analysis

library(tidyverse)
library(ggsignif)
library(cowplot)
library(ggpubr)
library(scales)
library(sjmisc)
library(kableExtra)
library(broom)
library(ComplexHeatmap)
library(ggVennDiagram)
library(biomaRt)
library(limma)
library(edgeR)
library(RColorBrewer)
palette_colors_mine <- colorRampPalette(colors = c("green","white","purple","red" ))(60)
scales::show_col(palette_colors_mine)

Version Author Date
9af9df6 reneeisnowhere 2023-11-09
bd0342c reneeisnowhere 2023-11-07

Knowles data analysis

Here I will attempt to recreate my correlation analysis on the knowles data using their troponin and RNAseq log2cpm.

### genes I want to know about
interest_genes <- read.csv("output/GOI_genelist.txt", row.names = 1)
trop_knowles <- read.csv("output/trop_knowles_fun.csv", row.names = 1)
Knowles_log2cpm <- readRDS("data/Knowles_log2cpm_real.RDS")
trop0.625 <- trop_knowles %>% 
  filter(dosage <1) 
store <- Knowles_log2cpm %>% 
  dplyr::select( 'ESGN',ends_with(c('0.625', '0'))) %>% 
  dplyr::filter(ESGN %in% interest_genes$ensembl_gene_id) %>% 
  pivot_longer(cols=!ESGN, names_to = "ind", values_to = "counts") %>% 
  separate(ind,into=c("cell_line","dosage"), sep = ":") %>%
  mutate(dosage = as.numeric(dosage)) %>% 
  full_join(., trop0.625, by=c("cell_line", "dosage")) %>% 
  group_by(cell_line) %>% 
  full_join(., interest_genes, by = c("ESGN" = "ensembl_gene_id"))
  
  
  ###new graph stuff
  for (gene in interest_genes$ensembl_gene_id){
    gene_plot <- store %>% 
      dplyr::filter(ESGN == gene) %>%
      ggplot(., aes(x=troponin, y=counts))+
      geom_point(aes(col=cell_line))+
      geom_smooth(method="lm")+
      
      facet_wrap(hgnc_symbol~dosage, scales="free")+
      theme_classic()+
      xlab("troponin I expression") +
      ylab("Gene counts in log2 cpm") +
      ggtitle(expression(paste("Correlation between counts and troponin I Knowles")))+
      scale_color_manual(values = palette_colors_mine, aesthetics = c("color", "fill"), guide=FALSE)+
      # guides(fill="none")+
     ggpubr:: stat_cor(method="spearman",
                       # cor.coef.name="rho",
               aes(label = paste(..r.label.., ..p.label.., sep = "~`,\n`~")),
               color = "black",
               label.x.npc = 0.01,
               label.y.npc=0.01, 
               size = 3)+
      theme(plot.title = element_text(size = rel(1.5), hjust = 0.5,face = "bold"),
            axis.title = element_text(size = 15, color = "black"),
            axis.ticks = element_line(size = 1.5),
            axis.text = element_text(size = 8, color = "black", angle = 20),
            strip.text.x = element_text(size = 12, color = "black", face = "italic"))
   print(gene_plot)
   
  }

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Knowles Boxplots of Fig9 genes

Knowles_log2cpm_box <- readRDS("data/Knowles_log2cpm_real.RDS")

store_box <- Knowles_log2cpm_box %>% 
  # dplyr::select( 'ESGN',ends_with(c('0.625', '0'))) %>% 
  dplyr::filter(ESGN %in% interest_genes$ensembl_gene_id) %>% 
  pivot_longer(cols=!ESGN, names_to = "ind", values_to = "counts") %>% 
  separate(ind,into=c("cell_line","dosage"), sep = ":") %>%
  mutate(dosage = as.numeric(dosage)) %>% 
  # full_join(., trop0.625, by=c("cell_line", "dosage")) %>% 
  group_by(cell_line) %>% 
  full_join(., interest_genes, by = c("ESGN" = "ensembl_gene_id"))
store_box %>% 
  mutate(dosage=factor(dosage, levels=c('0','0.000', '0.625','1.25', '2.5','5'))) %>% 
  ggplot(., aes(x=dosage,y=counts), group=dosage)+
  geom_boxplot()+
  facet_wrap(~hgnc_symbol)

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RNA-seq trial analysis

Analysis of expressed genes

RNA_seq_trial<- readRDS("data/RNA_seq_trial.RDS")

all_cpmcount <-  read_table("data/Counts_RNA_ERMatthews.txt")
cpm_count_main <- readRDS("data/cpmcount.RDS") %>% rownames_to_column(var = "ENTREZID")
colnames(cpm_count_main) <- colnames(all_cpmcount)


test_run_sample_list <- read.csv("data/test_run_sample_list.txt", row.names = 1)

colnames(RNA_seq_trial) <- c("ENTREZID",test_run_sample_list$Sample_ID)

lcpm_trial <- RNA_seq_trial %>% 
  column_to_rownames("ENTREZID") %>% 
  cpm(., log=TRUE) %>% 
  as.data.frame() #%>% 
 

row_means <- rowMeans(lcpm_trial)
x_trial <- lcpm_trial[row_means > 0,]
dim(x_trial)
[1] 13277     4
list_genes_trial <- rownames(x_trial)
ggVennDiagram::ggVennDiagram(list(list_genes_trial, cpm_count_main$ENTREZID),
                             category.names = c("Trialgenes","Maingenes"),
              show_intersect = TRUE,
              set_color = "black",
              label = "count",
              label_percent_digit = 1,
              label_size = 4,
              label_alpha = 0,
              label_color = "black",
              edge_lty = "solid", set_size = 4.5)#+

Correlation of counts files

lcpm_trial_full <- RNA_seq_trial %>% 
  column_to_rownames("ENTREZID") %>% 
  cpm(., log=TRUE) %>% 
  as.data.frame() %>% 
  rownames_to_column(var = "ENTREZID")

lcpm_trial_full %>%
  column_to_rownames(var="ENTREZID") %>%
  cor(.) %>% 
  Heatmap(.,layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(., i, j)), x, y, 
            gp = gpar(fontsize = 10))})

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lcpm_main <- all_cpmcount %>% 
  column_to_rownames("ENTREZID") %>% 
  cpm(., log=TRUE) %>% 
  as.data.frame() %>% 
  rownames_to_column(var = "ENTREZID") %>% 
  dplyr::select(ENTREZID, all_of(starts_with("DOX"))) %>% 
  dplyr::select(ENTREZID, all_of(ends_with("3h")))  
  
combined_data <- lcpm_main %>%
  full_join(., lcpm_trial_full, by= "ENTREZID") %>%
  column_to_rownames("ENTREZID") %>% 
  dplyr::select(starts_with("DOX"),`3hr_0.5`)%>% 
  cor(.,) 


  
  Heatmap(combined_data,column_title = "Full gene list",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(combined_data, i, j)), x, y, 
            gp = gpar(fontsize = 10))})

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  only79_ind <- lcpm_main %>%
  full_join(., lcpm_trial_full, by= "ENTREZID") %>% 
    dplyr::select(ENTREZID,'3hr_0.5',"DOX.4.3h") %>% 
    column_to_rownames("ENTREZID") %>% 
  cor(.,) 

  
  Heatmap(only79_ind,column_title = "Full gene list_79",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(only79_ind, i, j)), x, y, 
            gp = gpar(fontsize = 10))})

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lcpm_main_veh <- all_cpmcount %>% 
  column_to_rownames("ENTREZID") %>% 
  cpm(., log=TRUE) %>% 
  as.data.frame() %>% 
  rownames_to_column(var = "ENTREZID") %>% 
  dplyr::select(ENTREZID, all_of(c(starts_with("DOX"),starts_with("VEH")))) %>% 
   dplyr::select(ENTREZID, all_of(ends_with("3h")))  
  

combined_data_veh<- lcpm_main_veh %>%
  full_join(., lcpm_trial_full, by= "ENTREZID") %>% 
  column_to_rownames("ENTREZID") %>% 
  cor(.,) 
  
  
  
  Heatmap(combined_data_veh, column_title = "all genes in list, no filtering",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(combined_data_veh, i, j)), x, y, 
            gp = gpar(fontsize = 8))})

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lcpm_trial_filter_main <- lcpm_trial_full %>% 
  filter(ENTREZID %in% cpm_count_main$ENTREZID)
 


lcpm_trial_filter_main %>% 
column_to_rownames(var="ENTREZID") %>%
  cor(.) %>% 
  Heatmap(.,column_title = "Using 14,084 expressed genes from Main data",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(., i, j)), x, y, 
            gp = gpar(fontsize = 8))})

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lcpm_trial_filter <- lcpm_trial_full %>% 
  filter(ENTREZID %in% list_genes_trial)
 

lcpm_trial_filter %>% 
column_to_rownames(var="ENTREZID") %>%
  cor(.) %>% 
  Heatmap(.,column_title = "Using 13277 expressed genes",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(., i, j)), x, y, 
            gp = gpar(fontsize = 8))})

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lcpm_main_filter_trial <- lcpm_main_veh %>% 
  filter(ENTREZID %in% list_genes_trial)

lcpm_trial_filter %>% 
  full_join(., lcpm_main_filter_trial, by = "ENTREZID") %>% 
  column_to_rownames(var="ENTREZID") %>%
  cor(.) %>% 
  Heatmap(.,column_title = "Using 13277 expressed genes",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(., i, j)), x, y, 
            gp = gpar(fontsize = 8))})

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lcpm_trial_filter_main %>% 
  left_join(., lcpm_main, by = "ENTREZID") %>% 
  column_to_rownames(var="ENTREZID") %>%
  dplyr::select(DOX.4.3h,starts_with(("3hr")))%>% 
  cor(.) %>% 
  Heatmap(.,column_title = "Using 14084 expressed genes, just 79-1",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(., i, j)), x, y, 
            gp = gpar(fontsize = 8))})

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hr3_indv4 <- lcpm_trial_filter_main %>% 
  left_join(., lcpm_main, by = "ENTREZID") %>% 
  column_to_rownames(var="ENTREZID") %>%
  dplyr::select(DOX.4.3h,`3hr_0.5`,`3hr_0.0`)%>% 
  cor(.) %>% 
  Heatmap(.,column_title = "Using 14084 expressed genes, just 79-1",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(., i, j)), x, y, 
            gp = gpar(fontsize = 8))})
  
plot(hr3_indv4)

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correlation heatmap of 3hr Dox 1-6 individuals and trial data

lcpm_trial_filter_main %>% 
  left_join(., lcpm_main, by = "ENTREZID") %>% 
  column_to_rownames(var="ENTREZID") %>%
  dplyr::select(starts_with("DOX"),`3hr_0.5`)%>% 
  cor(.) %>% 
  Heatmap(.,column_title = "Using 14084 expressed genes, just 79-1 with all 3 hour samples",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(., i, j)), x, y, 
            gp = gpar(fontsize = 8))})

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lcpm_main %>% 
  left_join(., lcpm_trial_full, by = "ENTREZID") %>% 
  column_to_rownames(var="ENTREZID") %>%
  dplyr::select(starts_with("DOX"),`3hr_0.5`)%>% 
  cor(.) %>% 
  Heatmap(.,column_title = "all 29395 genes expriment with trial 0.5 uM",
          layer_fun = function(j, i, x, y, width, height, fill) {
              grid.text(sprintf("%.3f", pindex(., i, j)), x, y, 
            gp = gpar(fontsize = 8))})

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barplots

backGL <-read_csv("data/backGL.txt", 
    col_types = cols(...1 = col_skip()))

GOI_genelist <- read.csv("output/GOI_genelist.txt", row.names = 1)

cpm_boxplot_trial <-function(lcpm_trial, GOI, ylab) {
    ##GOI needs to be ENTREZID
  df_plot <- lcpm_trial %>% 
    dplyr::filter(rownames(.)== GOI) %>%
    pivot_longer(everything(),
                 names_to = "treatment",
                 values_to = "counts") %>%
    separate(treatment, c("time","conc"), sep= "_") %>%
    mutate(conc = factor(conc,levels=c('0.0','0.1','0.5','1.0'), labels = c ("NT", "0.1 uM", "0.5 uM", "1.0 uM")))
  
 plota <-  ggplot2::ggplot(df_plot, aes(x=conc, y= counts))+
    geom_col(position="identity")+
    theme_bw()+
    ylab(ylab)+
    xlab("")+
     ggtitle(paste(GOI))+
      theme(
        # strip.background = element_rect(fill = "white",linetype=1, linewidth = 0.5),
          plot.title = element_text(size=12,hjust = 0.5,face="bold"),
          axis.title = element_text(size = 10, color = "black"),
          axis.ticks = element_line(linewidth = 1.0),
          panel.background = element_rect(colour = "black", size=1),
          # axis.text.x = element_blank(),
          strip.text.x = element_text(margin = margin(2,0,2,0, "pt"),face = "bold"))
    print(plota)
}
  



for (g in seq(1:11)){
  datafilter <- GOI_genelist
  a <- GOI_genelist[g,3]
  # b <- datafilter[g,1]
  cpm_boxplot_trial(lcpm_trial,GOI=datafilter[g,1],
                           ylab =bquote(~italic(.(a))~log[2]~"cpm "))
  
}  

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above is expression of trial RNA seq data

Knowles log2cpm 24hr and my log2cpm 24hr

### Creating new interest genes for supplemental figure
# # SNP_genestop50 <- read.csv("output/TOP_50SNPreffile.csv", row.names = 1)
#  backGL <- read.csv("data/backGL.txt", row.names = 1)
# 
# DOX_de_genes_interest <- data.frame("hgnc_symbol"= c("PELI2","LGALS3", "PCCA", "SORT1", "GPSM2", "CLCC1", "LNPK", "GRAMD4", "CYREN", "LPL", "CELSR1", "TNS2", "ZNF740", "SLC28A3", "RMI1", "FRS2", "HDDC2"))
# 
# 
# DOX_de_genes_interest %>% 
#   left_join(., backGL, by= c("hgnc_symbol"="SYMBOL"))  %>% 
#   dplyr::select(!hgnc_symbol.y) %>% 
#   write.csv(.,"output/DOX_de_goi.csv")

DOX_de_genes_interest <- read.csv("output/DOX_de_goi.csv", row.names = 1)

kcpm <-  Knowles_log2cpm_box %>% 
  dplyr::filter(ESGN %in% DOX_de_genes_interest$ensembl_gene_id) %>% 
  pivot_longer(cols=!ESGN, names_to = "ind", values_to = "counts") %>% 
  separate(ind,into=c("cell_line","dosage"), sep = ":") %>%
  mutate(dosage = as.numeric(dosage)) %>% 
  # full_join(., trop0.625, by=c("cell_line", "dosage")) %>% 
  group_by(cell_line) %>% 
  full_join(., DOX_de_genes_interest, by = c("ESGN" = "ensembl_gene_id"))%>%  
  mutate(dosage=factor(dosage, levels=c('0','0.000', '0.625','1.25', '2.5','5'))) %>% 
  dplyr::filter(dosage==("0")|dosage == "0.625") %>% 
  mutate(expr="K")
  
lcpm_24h <- all_cpmcount %>% 
  column_to_rownames("ENTREZID") %>% 
  cpm(., log=TRUE) %>% 
  as.data.frame() %>% 
  rownames_to_column(var = "ENTREZID") %>% 
  dplyr::select(ENTREZID, all_of(starts_with(c("DOX","VEH")))) %>% 
  dplyr::select(ENTREZID, all_of(ends_with("24h")))  %>% 
  dplyr::filter(ENTREZID %in% DOX_de_genes_interest$ENTREZID) %>% 
  pivot_longer(cols=!ENTREZID, names_to = "ind", values_to = "counts") %>%   mutate(ENTREZID = as.numeric(ENTREZID)) %>% 
  full_join(., DOX_de_genes_interest, by = c("ENTREZID"="ENTREZID")) %>% 
  mutate(expr="ME") %>% 
  rename("ESGN"="ensembl_gene_id") %>% 
  separate(ind, into = c("dosage","cell_line",NA)) %>% 
  mutate(dosage=case_match(dosage,"DOX"~"0.5", .default = dosage)) 
  
lcpm_24h %>% 
  rbind(.,kcpm) %>% 
  mutate(dosage=factor(dosage, levels=c('0','0.625',"VEH","0.5"))) %>% 
  ggplot(., aes(x=dosage,y=counts), group=expr)+
  geom_boxplot()+
  facet_wrap(~hgnc_symbol, scales="free_y", nrow=3, ncol = 6 )#+

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  # geom_signif(
  #   comparisons = list(
  #     c('0', '0.5'),
  #     c('0', '0.625'),
  #     c('0.5','0.625')
  #   ),
  #   test = "t.test",
  #   tip_length = 0.01,
  #   map_signif_level = FALSE,
  #   textsize = 4,
  #   step_increase = 0.3
  # ) 

Replication of variance figures using Knowels data

# saveRDS(store_var, "data/Knowles_variation_data.RDS")
# store_var <- Knowles_log2cpm %>% 
#   dplyr::select( 'ESGN',ends_with(c('0.625', '0'))) %>% 
#   rowwise() %>% 
#   mutate(mean_DOX=mean(c_across(ends_with('0.625'))),
#          var_DOX=var(c_across(ends_with('0.625'))),
#         mean_NT=mean(c_across(ends_with('0'))),
#          var_NT=var(c_across(ends_with('0')))) %>% 
#   mutate(data=tidy(var.test(c_across(ends_with("0.625")),c_across(ends_with("0")))))# %>% 
  # dplyr::select("ESGN","mean_DOX","var_DOX","mean_NT", "var_NT","data")




store_var <- readRDS("data/Knowles_variation_data.RDS")

knowlesdrug<- store_var %>% 
  dplyr::select("ESGN","mean_DOX","var_DOX","mean_NT", "var_NT") %>% 
  pivot_longer(cols = !"ESGN", names_to = "short", values_to = "values") %>% 
  separate(short, into=c("calc","treatment")) #%>% 
knowlesdrug %>% 
  as.data.frame() %>% 
  dplyr::filter(calc == "mean") %>% 
  ggplot(., aes(x= treatment, y=values))+
  geom_boxplot()+
  ggtitle("Knowles Means across all genes")+
  geom_signif(
    comparisons = list(
      c("DOX", "NT")),
    test = "t.test",
    tip_length = 0.01,
    map_signif_level = FALSE
    # textsize = 4,
    # # y_position = 11,
    # step_increase = 0.05
  )

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knowlesdrug %>% 
  as.data.frame() %>% 
  dplyr::filter(calc == "var") %>% 
  ggplot(., aes(x= treatment, y=values))+
  geom_boxplot(outlier.shape= NA)+
  ggtitle(" Knowles Variance across all genes")+
  
  geom_signif(
    comparisons = list(
      c("DOX", "NT")),
    test = "t.test",
    tip_length = 0.01,
    y_position = 0.5,
    # vjust=1,
    map_signif_level = FALSE)+
 ylim(NA,1.25)

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Knowles replication data:

qvalue data

library(qvalue)


# p_list <- map_df(store_var$data,~as.data.frame(.x$p.value))
#  rownames(p_list) <- store_var$ESGN

p_list <- store_var %>% 
  unnest(data) %>% 
   dplyr::select(ESGN,statistic,p.value)
estDOXk <- qvalue(p_list$p.value) 
 hist(estDOXk)

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 plot(estDOXk)

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summary(estDOXk) 

Call:
qvalue(p = p_list$p.value)

pi0:    0.3993136   

Cumulative number of significant calls:

          <1e-04 <0.001 <0.01 <0.025 <0.05 <0.1    <1
p-value     1919   2762  4065   4832  5533 6453 12317
q-value     1616   2447  3895   4810  5723 6956 12317
local FDR   1143   1759  2724   3313  3800 4507 12317
knowlesvar <- data.frame("ESGN"=p_list$ESGN,"pvalues"=estDOXk$pvalues,"qvalues"=estDOXk$qvalues,"lfdr"= estDOXk$lfdr)  

intersecting_K <- knowlesvar %>% 
  filter(qvalues<0.1)
my_qval_list24 <- readRDS("data/qval24hr.RDS") 

EPI508_list <- my_qval_list24 %>% 
  dplyr::select(ENTREZID,EPIqvalues) %>% 
  filter(EPIqvalues<0.1) %>% 
  dplyr::select(ENTREZID) %>%
  mutate(ENTREZID=as.numeric(ENTREZID)) %>% 
  left_join(.,backGL, by="ENTREZID")
Knowlesvarlist <- readRDS("data/Knowlesvarlist.RDS")
  
# Knowlesvarlist<- getBM(attributes=my_attributes,filters ='ensembl_gene_id',values = intersecting_K$ESGN, mart = ensembl)

length(intersect(EPI508_list$ENTREZID,Knowlesvarlist$entrezgene_id))
[1] 367
intersect_genes <- EPI508_list %>% 
  dplyr::filter(ENTREZID %in% Knowlesvarlist$entrezgene_id)
highly_var_genelist <- intersect(EPI508_list$ENTREZID,Knowlesvarlist$entrezgene_id)
saveRDS(highly_var_genelist,"data/highly_var_genelist.RDS")
intersect_genes %>% 
kable(.,caption = "EPI Highly variable genes found in Knowles highly  variable DOX genes") %>% 
  kable_paper("striped", full_width = FALSE) %>%  
  kable_styling(full_width = TRUE, bootstrap_options = c("striped","hover")) %>% 
  scroll_box(width = "100%", height = "400px")
EPI Highly variable genes found in Knowles highly variable DOX genes
ENTREZID SYMBOL ensembl_gene_id hgnc_symbol
49856 WRAP73 ENSG00000116213 WRAP73
23463 ICMT ENSG00000116237 ICMT
5195 PEX14 ENSG00000142655 PEX14
57085 AGTRAP ENSG00000177674 AGTRAP
23207 PLEKHM2 ENSG00000116786 PLEKHM2
79363 CPLANE2 ENSG00000291382 CPLANE2
55160 ARHGEF10L ENSG00000074964 ARHGEF10L
55616 ASAP3 ENSG00000282854 ASAP3
57095 PITHD1 ENSG00000057757 PITHD1
11313 LYPLA2 ENSG00000011009 LYPLA2
84065 TMEM222 ENSG00000186501 TMEM222
23673 STX12 ENSG00000117758 STX12
56063 TMEM234 ENSG00000160055 TMEM234
3065 HDAC1 ENSG00000116478 HDAC1
127544 RNF19B ENSG00000116514 RNF19B
113444 SMIM12 ENSG00000163866 SMIM12
27095 TRAPPC3 ENSG00000054116 TRAPPC3
112950 MED8 ENSG00000159479 MED8
9670 IPO13 ENSG00000117408 IPO13
149483 CCDC17 ENSG00000159588 CCDC17
387338 NSUN4 ENSG00000117481 NSUN4
8543 LMO4 ENSG00000143013 LMO4
64858 DCLRE1B ENSG00000118655 DCLRE1B
128077 LIX1L ENSG00000271601 LIX1L
388695 LYSMD1 ENSG00000163155 LYSMD1
6944 VPS72 ENSG00000163159 VPS72
65005 MRPL9 ENSG00000143436 MRPL9
4000 LMNA ENSG00000160789 LMNA
11266 DUSP12 ENSG00000081721 DUSP12
261726 TIPRL ENSG00000143155 TIPRL
5279 PIGC ENSG00000135845 PIGC
83479 DDX59 ENSG00000118197 DDX59
134 ADORA1 ENSG00000163485 ADORA1
64853 AIDA ENSG00000186063 AIDA
163859 SDE2 ENSG00000143751 SDE2
5664 PSEN2 ENSG00000143801 PSEN2
65094 JMJD4 ENSG00000081692 JMJD4
126731 CCSAP ENSG00000154429 CCSAP
22796 COG2 ENSG00000135775 COG2
79723 SUV39H2 ENSG00000152455 SUV39H2
253430 IPMK ENSG00000151151 IPMK
26091 HERC4 ENSG00000148634 HERC4
219738 FAM241B ENSG00000171224 FAM241B
11319 ECD ENSG00000122882 ECD
5532 PPP3CB ENSG00000107758 PPP3CB
79933 SYNPO2L ENSG00000166317 SYNPO2L
27063 ANKRD1 ENSG00000148677 ANKRD1
118924 FRA10AC1 ENSG00000148690 FRA10AC1
282991 BLOC1S2 ENSG00000196072 BLOC1S2
10360 NPM3 ENSG00000107833 NPM3
9937 DCLRE1A ENSG00000198924 DCLRE1A
9184 BUB3 ENSG00000154473 BUB3
161 AP2A2 ENSG00000280759 AP2A2
7748 ZNF195 ENSG00000005801 ZNF195
10612 TRIM3 ENSG00000110171 TRIM3
23647 ARFIP2 ENSG00000132254 ARFIP2
65975 STK33 ENSG00000130413 STK33
113174 SAAL1 ENSG00000166788 SAAL1
627 BDNF ENSG00000176697 BDNF
79797 ZNF408 ENSG00000175213 ZNF408
10978 CLP1 ENSG00000172409 CLP1
55048 VPS37C ENSG00000167987 VPS37C
5436 POLR2G ENSG00000168002 POLR2G
144097 SPINDOC ENSG00000168005 SPINDOC
57410 SCYL1 ENSG00000142186 SCYL1
10524 KAT5 ENSG00000172977 KAT5
25855 BRMS1 ENSG00000174744 BRMS1
10432 RBM14 ENSG00000239306 RBM14
338692 ANKRD13D ENSG00000172932 ANKRD13D
5883 RAD9A ENSG00000172613 RAD9A
5499 PPP1CA ENSG00000172531 PPP1CA
2950 GSTP1 ENSG00000084207 GSTP1
116985 ARAP1 ENSG00000186635 ARAP1
5612 THAP12 ENSG00000137492 THAP12
56946 EMSY ENSG00000158636 EMSY
282679 AQP11 ENSG00000178301 AQP11
51585 PCF11 ENSG00000165494 PCF11
60492 CCDC90B ENSG00000137500 CCDC90B
9440 MED17 ENSG00000042429 MED17
54851 ANKRD49 ENSG00000168876 ANKRD49
10929 SRSF8 ENSG00000263465 SRSF8
5049 PAFAH1B2 ENSG00000168092 PAFAH1B2
219902 TLCD5 ENSG00000181264 TLCD5
219899 TBCEL ENSG00000154114 TBCEL
9538 EI24 ENSG00000149547 EI24
219833 KCNJ5-AS1 ENSG00000174370 KCNJ5-AS1
57102 C12orf4 ENSG00000047621 C12orf4
8079 MLF2 ENSG00000089693 MLF2
25977 NECAP1 ENSG00000089818 NECAP1
79657 RPAP3 ENSG00000005175 RPAP3
55652 SLC48A1 ENSG00000211584 SLC48A1
1019 CDK4 ENSG00000135446 CDK4
23041 MON2 ENSG00000061987 MON2
29110 TBK1 ENSG00000183735 TBK1
253827 MSRB3 ENSG00000174099 MSRB3
117177 RAB3IP ENSG00000127328 RAB3IP
22822 PHLDA1 ENSG00000139289 PHLDA1
89795 NAV3 ENSG00000067798 NAV3
121053 NOPCHAP1 ENSG00000151131 NOPCHAP1
1407 CRY1 ENSG00000008405 CRY1
51228 GLTP ENSG00000139433 GLTP
400073 C12orf76 ENSG00000174456 C12orf76
5564 PRKAB1 ENSG00000111725 PRKAB1
51499 TRIAP1 ENSG00000170855 TRIAP1
56616 DIABLO ENSG00000184047 DIABLO
387893 KMT5A ENSG00000183955 KMT5A
11066 SNRNP35 ENSG00000184209 SNRNP35
5901 RAN ENSG00000132341 RAN
100289635 ZNF605 ENSG00000196458 ZNF605
221178 SPATA13 ENSG00000182957 SPATA13
283537 SLC46A3 ENSG00000139508 SLC46A3
2963 GTF2F2 ENSG00000188342 GTF2F2
337867 UBAC2 ENSG00000134882 UBAC2
3981 LIG4 ENSG00000174405 LIG4
84945 ABHD13 ENSG00000139826 ABHD13
3621 ING1 ENSG00000153487 ING1
253959 RALGAPA1 ENSG00000174373 RALGAPA1
54813 KLHL28 ENSG00000179454 KLHL28
6617 SNAPC1 ENSG00000023608 SNAPC1
123016 TTC8 ENSG00000165533 TTC8
51527 GSKIP ENSG00000100744 GSKIP
2972 BRF1 ENSG00000185024 BRF1
22893 BAHD1 ENSG00000140320 BAHD1
9325 TRIP4 ENSG00000103671 TRIP4
5371 PML ENSG00000140464 PML
60490 PPCDC ENSG00000138621 PPCDC
79631 EFL1 ENSG00000140598 EFL1
84219 WDR24 ENSG00000127580 WDR24
23059 CLUAP1 ENSG00000103351 CLUAP1
2072 ERCC4 ENSG00000175595 ERCC4
91949 COG7 ENSG00000168434 COG7
23568 ARL2BP ENSG00000102931 ARL2BP
29070 CCDC113 ENSG00000103021 CCDC113
8824 CES2 ENSG00000172831 CES2
1874 E2F4 ENSG00000205250 E2F4
6560 SLC12A4 ENSG00000124067 SLC12A4
146198 ZFP90 ENSG00000184939 ZFP90
54386 TERF2IP ENSG00000166848 TERF2IP
5119 CHMP1A ENSG00000131165 CHMP1A
64359 NXN ENSG00000280563 NXN
5048 PAFAH1B1 ENSG00000007168 PAFAH1B1
388324 INCA1 ENSG00000196388 INCA1
9135 RABEP1 ENSG00000029725 RABEP1
57336 ZNF287 ENSG00000141040 ZNF287
79736 TEFM ENSG00000172171 TEFM
55813 UTP6 ENSG00000108651 UTP6
54475 NLE1 ENSG00000073536 NLE1
5193 PEX12 ENSG00000108733 PEX12
22794 CASC3 ENSG00000108349 CASC3
3292 HSD17B1 ENSG00000108786 HSD17B1
10614 HEXIM1 ENSG00000186834 HEXIM1
114881 OSBPL7 ENSG00000006025 OSBPL7
29916 SNX11 ENSG00000002919 SNX11
8405 SPOP ENSG00000121067 SPOP
10237 SLC35B1 ENSG00000121073 SLC35B1
81558 FAM117A ENSG00000121104 FAM117A
55316 RSAD1 ENSG00000136444 RSAD1
8161 COIL ENSG00000121058 COIL
6426 SRSF1 ENSG00000136450 SRSF1
54903 MKS1 ENSG00000011143 MKS1
55771 PRR11 ENSG00000068489 PRR11
284161 GDPD1 ENSG00000153982 GDPD1
6198 RPS6KB1 ENSG00000108443 RPS6KB1
57508 INTS2 ENSG00000108506 INTS2
84923 FAM104A ENSG00000133193 FAM104A
55028 C17orf80 ENSG00000141219 C17orf80
6730 SRP68 ENSG00000167881 SRP68
9489 PGS1 ENSG00000087157 PGS1
9775 EIF4A3 ENSG00000291508 EIF4A3
57521 RPTOR ENSG00000141564 RPTOR
79643 CHMP6 ENSG00000176108 CHMP6
5881 RAC3 ENSG00000169750 RAC3
8780 RIOK3 ENSG00000101782 RIOK3
55364 IMPACT ENSG00000154059 IMPACT
54531 MIER2 ENSG00000105556 MIER2
126308 MOB3A ENSG00000172081 MOB3A
29985 SLC39A3 ENSG00000141873 SLC39A3
51343 FZR1 ENSG00000105325 FZR1
51588 PIAS4 ENSG00000105229 PIAS4
6455 SH3GL1 ENSG00000141985 SH3GL1
5609 MAP2K7 ENSG00000076984 MAP2K7
79603 CERS4 ENSG00000090661 CERS4
93134 ZNF561 ENSG00000171469 ZNF561
126070 ZNF440 ENSG00000171295 ZNF440
2193 FARSA ENSG00000179115 FARSA
85360 SYDE1 ENSG00000105137 SYDE1
8907 AP1M1 ENSG00000072958 AP1M1
54858 PGPEP1 ENSG00000130517 PGPEP1
93436 ARMC6 ENSG00000105676 ARMC6
79414 LRFN3 ENSG00000126243 LRFN3
163087 ZNF383 ENSG00000188283 ZNF383
84503 ZNF527 ENSG00000189164 ZNF527
22835 ZFP30 ENSG00000120784 ZFP30
284323 ZNF780A ENSG00000280568 ZNF780A
29950 SERTAD1 ENSG00000197019 SERTAD1
90324 CCDC97 ENSG00000142039 CCDC97
56006 SMG9 ENSG00000105771 SMG9
7773 ZNF230 ENSG00000159882 ZNF230
7769 ZNF226 ENSG00000167380 ZNF226
9668 ZNF432 ENSG00000256087 ZNF432
147657 ZNF480 ENSG00000198464 ZNF480
112724 RDH13 ENSG00000278149 RDH13
163033 ZNF579 ENSG00000218891 ZNF579
147694 ZNF548 ENSG00000188785 ZNF548
100293516 ZNF587B ENSG00000269343 ZNF587B
25799 ZNF324 ENSG00000083812 ZNF324
7260 EIPR1 ENSG00000032389 EIPR1
55006 TRMT61B ENSG00000171103 TRMT61B
253635 GPATCH11 ENSG00000152133 GPATCH11
92906 HNRNPLL ENSG00000143889 HNRNPLL
8491 MAP4K3 ENSG00000011566 MAP4K3
57504 MTA3 ENSG00000057935 MTA3
53335 BCL11A ENSG00000119866 BCL11A
5861 RAB1A ENSG00000138069 RAB1A
27332 ZNF638 ENSG00000075292 ZNF638
8446 DUSP11 ENSG00000291483 DUSP11
1716 DGUOK ENSG00000114956 DGUOK
84173 ELMOD3 ENSG00000115459 ELMOD3
129303 TMEM150A ENSG00000168890 TMEM150A
5903 RANBP2 ENSG00000153201 RANBP2
10254 STAM2 ENSG00000115145 STAM2
10213 PSMD14 ENSG00000115233 PSMD14
115677 NOSTRIN ENSG00000275326 NOSTRIN
79828 METTL8 ENSG00000123600 METTL8
80067 DCAF17 ENSG00000115827 DCAF17
129831 RBM45 ENSG00000155636 RBM45
3628 INPP1 ENSG00000151689 INPP1
6775 STAT4 ENSG00000138378 STAT4
9330 GTF3C3 ENSG00000119041 GTF3C3
57404 CYP20A1 ENSG00000119004 CYP20A1
54891 INO80D ENSG00000283510 INO80D
377007 KLHL30 ENSG00000168427 KLHL30
4735 SEPTIN2 ENSG00000168385 SEPTIN2
80023 NRSN2 ENSG00000125841 NRSN2
55968 NSFL1C ENSG00000088833 NSFL1C
55317 AP5S1 ENSG00000125843 AP5S1
64412 GZF1 ENSG00000125812 GZF1
51230 PHF20 ENSG00000025293 PHF20
25980 AAR2 ENSG00000131043 AAR2
63905 MANBAL ENSG00000291969 MANBAL
10904 BLCAP ENSG00000166619 BLCAP
60625 DHX35 ENSG00000101452 DHX35
51098 IFT52 ENSG00000101052 IFT52
51006 SLC35C2 ENSG00000080189 SLC35C2
10564 ARFGEF2 ENSG00000124198 ARFGEF2
11054 OGFR ENSG00000060491 OGFR
80331 DNAJC5 ENSG00000101152 DNAJC5
29104 N6AMT1 ENSG00000156239 N6AMT1
84221 SPATC1L ENSG00000160284 SPATC1L
51586 MED15 ENSG00000099917 MED15
6598 SMARCB1 ENSG00000275837 SMARCB1
84700 MYO18B ENSG00000133454 MYO18B
402055 SRRD ENSG00000100104 SRRD
84164 ASCC2 ENSG00000100325 ASCC2
23780 APOL2 ENSG00000128335 APOL2
129138 ANKRD54 ENSG00000100124 ANKRD54
9463 PICK1 ENSG00000100151 PICK1
84247 RTL6 ENSG00000188636 RTL6
132001 TAMM41 ENSG00000279643 TAMM41
23609 MKRN2 ENSG00000075975 MKRN2
22908 SACM1L ENSG00000211456 SACM1L
51385 ZNF589 ENSG00000164048 ZNF589
64925 CCDC71 ENSG00000177352 CCDC71
11070 TMEM115 ENSG00000126062 TMEM115
28972 SPCS1 ENSG00000114902 SPCS1
25871 NEPRO ENSG00000163608 NEPRO
55254 TMEM39A ENSG00000176142 TMEM39A
131601 TPRA1 ENSG00000163870 TPRA1
7879 RAB7A ENSG00000075785 RAB7A
51122 COMMD2 ENSG00000114744 COMMD2
64393 ZMAT3 ENSG00000172667 ZMAT3
86 ACTL6A ENSG00000136518 ACTL6A
55486 PARL ENSG00000175193 PARL
90407 TMEM41A ENSG00000163900 TMEM41A
1487 CTBP1 ENSG00000159692 CTBP1
7469 NELFA ENSG00000185049 NELFA
152 ADRA2C ENSG00000184160 ADRA2C
132789 GNPDA2 ENSG00000163281 GNPDA2
10606 PAICS ENSG00000128050 PAICS
92597 MOB1B ENSG00000173542 MOB1B
266812 NAP1L5 ENSG00000177432 NAP1L5
56916 SMARCAD1 ENSG00000163104 SMARCAD1
55212 BBS7 ENSG00000138686 BBS7
90826 PRMT9 ENSG00000164169 PRMT9
4750 NEK1 ENSG00000137601 NEK1
55100 WDR70 ENSG00000082068 WDR70
55814 BDP1 ENSG00000274803 BDP1
79810 PTCD2 ENSG00000049883 PTCD2
167153 TENT2 ENSG00000164329 TENT2
9765 ZFYVE16 ENSG00000039319 ZFYVE16
55781 RIOK2 ENSG00000058729 RIOK2
90355 MACIR ENSG00000181751 MACIR
153733 CCDC112 ENSG00000164221 CCDC112
153443 SRFBP1 ENSG00000151304 SRFBP1
8572 PDLIM4 ENSG00000131435 PDLIM4
202052 DNAJC18 ENSG00000170464 DNAJC18
23438 HARS2 ENSG00000112855 HARS2
10826 FAXDC2 ENSG00000170271 FAXDC2
9443 MED7 ENSG00000155868 MED7
5917 RARS1 ENSG00000113643 RARS1
80315 CPEB4 ENSG00000113742 CPEB4
8899 PRPF4B ENSG00000112739 PRPF4B
10473 HMGN4 ENSG00000292175 HMGN4
7746 ZSCAN9 ENSG00000137185 ZSCAN9
8449 DHX16 ENSG00000233049 DHX16
57827 C6orf47 ENSG00000228177 C6orf47
578 BAK1 ENSG00000030110 BAK1
5467 PPARD ENSG00000112033 PPARD
6428 SRSF3 ENSG00000112081 SRSF3
9477 MED20 ENSG00000124641 MED20
9533 POLR1C ENSG00000171453 POLR1C
26036 ZNF451 ENSG00000112200 ZNF451
51715 RAB23 ENSG00000112210 RAB23
25821 MTO1 ENSG00000135297 MTO1
57226 LYRM2 ENSG00000083099 LYRM2
23376 UFL1 ENSG00000014123 UFL1
26235 FBXL4 ENSG00000112234 FBXL4
91749 MFSD4B ENSG00000173214 MFSD4B
10758 TRAF3IP2 ENSG00000056972 TRAF3IP2
5689 PSMB1 ENSG00000281184 PSMB1
5575 PRKAR1B ENSG00000188191 PRKAR1B
90639 COX19 ENSG00000240230 COX19
84262 PSMG3 ENSG00000157778 PSMG3
8379 MAD1L1 ENSG00000002822 MAD1L1
54476 RNF216 ENSG00000011275 RNF216
221830 POLR1F ENSG00000105849 POLR1F
3364 HUS1 ENSG00000136273 HUS1
55695 NSUN5 ENSG00000130305 NSUN5
9569 GTF2IRD1 ENSG00000006704 GTF2IRD1
113878 DTX2 ENSG00000282379 DTX2
6717 SRI ENSG00000075142 SRI
9069 CLDN12 ENSG00000157224 CLDN12
10898 CPSF4 ENSG00000160917 CPSF4
3268 AGFG2 ENSG00000106351 AGFG2
5001 ORC5 ENSG00000164815 ORC5
60561 RINT1 ENSG00000135249 RINT1
64418 TMEM168 ENSG00000146802 TMEM168
27153 ZNF777 ENSG00000196453 ZNF777
80346 REEP4 ENSG00000168476 REEP4
5533 PPP3CC ENSG00000120910 PPP3CC
157313 CDCA2 ENSG00000184661 CDCA2
23087 TRIM35 ENSG00000104228 TRIM35
157574 FBXO16 ENSG00000214050 FBXO16
7336 UBE2V2 ENSG00000169139 UBE2V2
90362 FAM110B ENSG00000169122 FAM110B
55824 PAG1 ENSG00000076641 PAG1
55656 INTS8 ENSG00000164941 INTS8
51123 ZNF706 ENSG00000120963 ZNF706
51105 PHF20L1 ENSG00000129292 PHF20L1
203062 TSNARE1 ENSG00000171045 TSNARE1
55958 KLHL9 ENSG00000198642 KLHL9
54840 APTX ENSG00000137074 APTX
55035 NOL8 ENSG00000198000 NOL8
10592 SMC2 ENSG00000136824 SMC2
5998 RGS3 ENSG00000138835 RGS3
51552 RAB14 ENSG00000119396 RAB14
399665 FAM102A ENSG00000167106 EEIG1
84885 ZDHHC12 ENSG00000160446 ZDHHC12
5900 RALGDS ENSG00000160271 RALGDS
6837 MED22 ENSG00000281022 MED22
57109 REXO4 ENSG00000280706 REXO4
92715 DPH7 ENSG00000148399 DPH7
23708 GSPT2 ENSG00000189369 GSPT2
29934 SNX12 ENSG00000147164 SNX12
139596 UPRT ENSG00000094841 UPRT
64860 ARMCX5 ENSG00000125962 ARMCX5
644596 SMIM10L2B ENSG00000196972 SMIM10L2B
# saveRDS(Knowlesvarlist,"data/Knowlesvarlist.RDS")

GO analysis of Highly Variable genes

I am using two backgrounds:
(1) the expressed background of the expressed genes in my data in the A set (n = 14,084)
(2) the full EPI highly variable genes from my data in the B set (n = 508) set 2 or B did not yield anything!

A set

library(gprofiler2)
library(org.Hs.eg.db)
### This is for retrieving all genes annotated in the Herpes simplex virus list
# https://support.bioconductor.org/p/109871/
library(limma)
tab <- getGeneKEGGLinks(species="hsa")
tab$Symbol <- mapIds(org.Hs.eg.db, tab$GeneID,
                       column="SYMBOL", keytype="ENTREZID")
KEGG_05168 <- tab %>% dplyr::filter(PathwayID=="hsa05168")

# backGL <-read_csv("data/backGL.txt", 
#     col_types = cols(...1 = col_skip()))

# SETA_resgenes <- gost(query = intersect_genes$SYMBOL,
#                     organism = "hsapiens",
#                     significant = FALSE,
#                     ordered_query = TRUE,
#                     domain_scope = "custom",
#                     measure_underrepresentation = FALSE,
#                     evcodes = FALSE,
#                     user_threshold = 0.05,
#                     correction_method = c("fdr"),
#                     custom_bg = backGL$SYMBOL,
#                     sources=c("GO:BP","KEGG"))
# saveRDS(SETA_resgenes,"data/DEG-GO/SETA_resgenes.RDS")
SETA_resgenes <- readRDS("data/DEG-GO/SETA_resgenes.RDS")

Set_A_genes <- gostplot(SETA_resgenes, capped = FALSE, interactive = TRUE)
Set_A_genes
setA_table <- SETA_resgenes$result %>% 
  dplyr::select(c(source, term_id,
                  term_name,intersection_size, 
                   term_size, p_value))# %>% 

list_intersect_path <- KEGG_05168 %>% 
  filter(Symbol%in% intersect_genes$SYMBOL) 

list_intersect_path%>% 
  kable(., caption = "List of intersecting genes from the Herpes simplex KEGG pathway") %>%
  kable_paper("striped", full_width = FALSE) %>%
  kable_styling(
    full_width = FALSE,
    position = "left",
    bootstrap_options = c("striped", "hover")
  ) %>%
  scroll_box(width = "100%", height = "400px")
List of intersecting genes from the Herpes simplex KEGG pathway
GeneID PathwayID Symbol
100289635 hsa05168 ZNF605
10929 hsa05168 SRSF8
126070 hsa05168 ZNF440
146198 hsa05168 ZFP90
147657 hsa05168 ZNF480
147694 hsa05168 ZNF548
163087 hsa05168 ZNF383
22835 hsa05168 ZFP30
25799 hsa05168 ZNF324
27153 hsa05168 ZNF777
284323 hsa05168 ZNF780A
29110 hsa05168 TBK1
51385 hsa05168 ZNF589
5371 hsa05168 PML
5499 hsa05168 PPP1CA
578 hsa05168 BAK1
6426 hsa05168 SRSF1
6428 hsa05168 SRSF3
7748 hsa05168 ZNF195
7769 hsa05168 ZNF226
7773 hsa05168 ZNF230
84503 hsa05168 ZNF527
93134 hsa05168 ZNF561
9668 hsa05168 ZNF432
setA_table %>% 
  kable(., caption = "List of GO BP and KEGG pathways enriched") %>%
  kable_paper("striped", full_width = FALSE) %>%
  kable_styling(
    full_width = FALSE,
    position = "left",
    bootstrap_options = c("striped", "hover")
  ) %>%
  scroll_box(width = "100%", height = "400px")
List of GO BP and KEGG pathways enriched
source term_id term_name intersection_size term_size p_value
GO:BP GO:0042770 signal transduction in response to DNA damage 10 180 0.0317931
GO:BP GO:0031848 protection from non-homologous end joining at telomere 3 8 0.0953646
GO:BP GO:0051640 organelle localization 8 521 0.1059227
GO:BP GO:0009648 photoperiodism 3 24 0.1059227
GO:BP GO:0032984 protein-containing complex disassembly 10 219 0.1059227
GO:BP GO:0006367 transcription initiation at RNA polymerase II promoter 5 95 0.1059227
GO:BP GO:0006368 transcription elongation by RNA polymerase II 10 109 0.1059227
GO:BP GO:0044774 mitotic DNA integrity checkpoint signaling 6 84 0.1059227
GO:BP GO:0006383 transcription by RNA polymerase III 6 61 0.1059227
GO:BP GO:0044773 mitotic DNA damage checkpoint signaling 6 80 0.1059227
GO:BP GO:1902455 negative regulation of stem cell population maintenance 3 21 0.1059227
GO:BP GO:0044721 protein import into peroxisome matrix, substrate release 2 5 0.1059227
GO:BP GO:1902459 positive regulation of stem cell population maintenance 5 45 0.1059227
GO:BP GO:0015786 UDP-glucose transmembrane transport 2 3 0.1059227
GO:BP GO:0033043 regulation of organelle organization 22 1002 0.1059227
GO:BP GO:0030038 contractile actin filament bundle assembly 2 95 0.1059227
GO:BP GO:0033133 positive regulation of glucokinase activity 2 4 0.1059227
GO:BP GO:0006481 C-terminal protein methylation 1 2 0.1059227
GO:BP GO:0110020 regulation of actomyosin structure organization 2 90 0.1059227
GO:BP GO:0090201 negative regulation of release of cytochrome c from mitochondria 4 17 0.1059227
GO:BP GO:0001666 response to hypoxia 5 235 0.1059227
GO:BP GO:0042323 negative regulation of circadian sleep/wake cycle, non-REM sleep 1 1 0.1059227
GO:BP GO:0070897 transcription preinitiation complex assembly 8 66 0.1059227
GO:BP GO:0043967 histone H4 acetylation 5 42 0.1059227
GO:BP GO:0016233 telomere capping 4 34 0.1059227
GO:BP GO:0016236 macroautophagy 18 308 0.1059227
GO:BP GO:0036258 multivesicular body assembly 4 32 0.1059227
GO:BP GO:0036257 multivesicular body organization 4 33 0.1059227
GO:BP GO:1902855 regulation of non-motile cilium assembly 1 9 0.1059227
GO:BP GO:0009649 entrainment of circadian clock 3 26 0.1059227
GO:BP GO:2001252 positive regulation of chromosome organization 9 103 0.1059227
GO:BP GO:0006354 DNA-templated transcription elongation 11 125 0.1059227
GO:BP GO:0006352 DNA-templated transcription initiation 13 131 0.1059227
GO:BP GO:0002674 negative regulation of acute inflammatory response 2 6 0.1059227
GO:BP GO:0048144 fibroblast proliferation 6 89 0.1059227
GO:BP GO:0048145 regulation of fibroblast proliferation 5 75 0.1059227
GO:BP GO:0032231 regulation of actin filament bundle assembly 2 90 0.1059227
GO:BP GO:0031570 DNA integrity checkpoint signaling 7 130 0.1059227
GO:BP GO:1901987 regulation of cell cycle phase transition 21 387 0.1059227
GO:BP GO:1901988 negative regulation of cell cycle phase transition 8 234 0.1059227
GO:BP GO:0046499 S-adenosylmethioninamine metabolic process 1 1 0.1059227
GO:BP GO:0046498 S-adenosylhomocysteine metabolic process 1 2 0.1059227
GO:BP GO:0032244 positive regulation of nucleoside transport 1 1 0.1059227
GO:BP GO:0061919 process utilizing autophagic mechanism 24 516 0.1059227
GO:BP GO:0007093 mitotic cell cycle checkpoint signaling 6 137 0.1059227
GO:BP GO:0007346 regulation of mitotic cell cycle 23 438 0.1059227
GO:BP GO:0061956 penetration of cumulus oophorus 1 1 0.1059227
GO:BP GO:0010453 regulation of cell fate commitment 2 26 0.1059227
GO:BP GO:0003274 endocardial cushion fusion 1 5 0.1059227
GO:BP GO:0010948 negative regulation of cell cycle process 9 271 0.1059227
GO:BP GO:0062232 prostanoid catabolic process 1 2 0.1059227
GO:BP GO:0036293 response to decreased oxygen levels 5 248 0.1059227
GO:BP GO:0045786 negative regulation of cell cycle 12 337 0.1059227
GO:BP GO:0045724 positive regulation of cilium assembly 1 25 0.1059227
GO:BP GO:0032784 regulation of DNA-templated transcription elongation 9 99 0.1059227
GO:BP GO:0060260 regulation of transcription initiation by RNA polymerase II 7 70 0.1059227
GO:BP GO:0098732 macromolecule deacylation 8 92 0.1059227
GO:BP GO:0070482 response to oxygen levels 5 271 0.1059227
GO:BP GO:0006302 double-strand break repair 15 278 0.1059227
GO:BP GO:0032900 negative regulation of neurotrophin production 1 1 0.1059227
GO:BP GO:1902857 positive regulation of non-motile cilium assembly 1 7 0.1059227
GO:BP GO:0034243 regulation of transcription elongation by RNA polymerase II 9 85 0.1059227
GO:BP GO:0030330 DNA damage response, signal transduction by p53 class mediator 5 70 0.1059227
GO:BP GO:0036250 peroxisome transport along microtubule 1 1 0.1059227
GO:BP GO:0043149 stress fiber assembly 2 95 0.1059227
GO:BP GO:1905344 prostaglandin catabolic process 1 2 0.1059227
GO:BP GO:0043153 entrainment of circadian clock by photoperiod 3 23 0.1059227
GO:BP GO:0043558 regulation of translational initiation in response to stress 3 16 0.1059227
GO:BP GO:0043247 telomere maintenance in response to DNA damage 5 27 0.1059227
GO:BP GO:0000075 cell cycle checkpoint signaling 8 184 0.1059227
GO:BP GO:1903047 mitotic cell cycle process 33 690 0.1059227
GO:BP GO:0000070 mitotic sister chromatid segregation 8 178 0.1059227
GO:BP GO:0035601 protein deacylation 8 91 0.1059227
GO:BP GO:0006914 autophagy 24 516 0.1059227
GO:BP GO:0016575 histone deacetylation 6 62 0.1059227
GO:BP GO:0042659 regulation of cell fate specification 2 23 0.1059227
GO:BP GO:0000077 DNA damage checkpoint signaling 7 121 0.1059227
GO:BP GO:0007032 endosome organization 7 93 0.1059227
GO:BP GO:0016560 protein import into peroxisome matrix, docking 1 3 0.1059227
GO:BP GO:0016561 protein import into peroxisome matrix, translocation 1 4 0.1059227
GO:BP GO:0007623 circadian rhythm 7 158 0.1059227
GO:BP GO:0000226 microtubule cytoskeleton organization 3 551 0.1059227
GO:BP GO:0019068 virion assembly 5 33 0.1059227
GO:BP GO:0006998 nuclear envelope organization 6 54 0.1059227
GO:BP GO:0018410 C-terminal protein amino acid modification 1 10 0.1059227
GO:BP GO:0051492 regulation of stress fiber assembly 5 81 0.1059227
GO:BP GO:0007010 cytoskeleton organization 5 1188 0.1059227
GO:BP GO:0048264 determination of ventral identity 1 1 0.1061980
GO:BP GO:0010569 regulation of double-strand break repair via homologous recombination 5 64 0.1061980
GO:BP GO:0006974 DNA damage response 18 798 0.1061980
GO:BP GO:0042754 negative regulation of circadian rhythm 2 8 0.1069357
GO:BP GO:0044770 cell cycle phase transition 24 496 0.1069357
GO:BP GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage 2 7 0.1069357
GO:BP GO:0045324 late endosome to vacuole transport 4 36 0.1069357
GO:BP GO:0002084 protein depalmitoylation 2 10 0.1069357
GO:BP GO:1903251 multi-ciliated epithelial cell differentiation 2 6 0.1069357
GO:BP GO:0032922 circadian regulation of gene expression 4 61 0.1069357
GO:BP GO:0002228 natural killer cell mediated immunity 2 34 0.1069357
GO:BP GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 4 35 0.1069357
GO:BP GO:0098734 macromolecule depalmitoylation 2 11 0.1069357
GO:BP GO:0044819 mitotic G1/S transition checkpoint signaling 3 30 0.1069357
GO:BP GO:0055001 muscle cell development 4 166 0.1069357
GO:BP GO:0006303 double-strand break repair via nonhomologous end joining 4 62 0.1069357
GO:BP GO:0042752 regulation of circadian rhythm 5 91 0.1069357
GO:BP GO:0000301 retrograde transport, vesicle recycling within Golgi 2 9 0.1069357
GO:BP GO:0042267 natural killer cell mediated cytotoxicity 2 34 0.1069357
GO:BP GO:1901673 regulation of mitotic spindle assembly 3 23 0.1069357
GO:BP GO:1990755 mitotic spindle microtubule depolymerization 1 1 0.1069357
GO:BP GO:0061572 actin filament bundle organization 2 138 0.1069357
GO:BP GO:0016050 vesicle organization 16 317 0.1069357
GO:BP GO:0051053 negative regulation of DNA metabolic process 6 117 0.1069357
GO:BP GO:0039702 viral budding via host ESCRT complex 3 21 0.1069357
GO:BP GO:0006446 regulation of translational initiation 5 72 0.1069357
GO:BP GO:0007049 cell cycle 36 1516 0.1069357
GO:BP GO:0051017 actin filament bundle assembly 2 136 0.1069357
GO:BP GO:0051726 regulation of cell cycle 43 940 0.1069357
GO:BP GO:0046128 purine ribonucleoside metabolic process 1 16 0.1069357
GO:BP GO:0016072 rRNA metabolic process 15 252 0.1069357
GO:BP GO:0061343 cell adhesion involved in heart morphogenesis 1 6 0.1069357
GO:BP GO:0016558 protein import into peroxisome matrix 1 14 0.1069357
GO:BP GO:0061198 fungiform papilla formation 1 3 0.1069357
GO:BP GO:0031571 mitotic G1 DNA damage checkpoint signaling 3 30 0.1069357
GO:BP GO:0070933 histone H4 deacetylation 1 3 0.1069357
GO:BP GO:0031627 telomeric loop formation 1 2 0.1069357
GO:BP GO:0043508 negative regulation of JUN kinase activity 2 13 0.1069357
GO:BP GO:0043555 regulation of translation in response to stress 3 24 0.1069357
GO:BP GO:1903301 positive regulation of hexokinase activity 2 5 0.1070583
GO:BP GO:2001233 regulation of apoptotic signaling pathway 12 319 0.1081479
GO:BP GO:0046755 viral budding 3 24 0.1081479
GO:BP GO:0031468 nuclear membrane reassembly 4 25 0.1081479
GO:BP GO:0019827 stem cell population maintenance 6 151 0.1081479
GO:BP GO:0045930 negative regulation of mitotic cell cycle 13 209 0.1081479
GO:BP GO:0022411 cellular component disassembly 19 429 0.1081479
GO:BP GO:0042278 purine nucleoside metabolic process 1 20 0.1081479
GO:BP GO:0032509 endosome transport via multivesicular body sorting pathway 4 41 0.1082602
GO:BP GO:0045815 transcription initiation-coupled chromatin remodeling 4 35 0.1088100
GO:BP GO:0006996 organelle organization 6 2976 0.1088100
GO:BP GO:0010564 regulation of cell cycle process 30 622 0.1088100
GO:BP GO:0072663 establishment of protein localization to peroxisome 1 19 0.1088100
GO:BP GO:2000779 regulation of double-strand break repair 8 123 0.1088100
GO:BP GO:1902017 regulation of cilium assembly 1 55 0.1088100
GO:BP GO:0010833 telomere maintenance via telomere lengthening 5 74 0.1088100
GO:BP GO:2000142 regulation of DNA-templated transcription initiation 7 77 0.1088100
GO:BP GO:1901798 positive regulation of signal transduction by p53 class mediator 3 28 0.1088100
GO:BP GO:0045814 negative regulation of gene expression, epigenetic 3 94 0.1088100
GO:BP GO:0032242 regulation of nucleoside transport 1 2 0.1088100
GO:BP GO:0072662 protein localization to peroxisome 1 19 0.1088100
GO:BP GO:0097190 apoptotic signaling pathway 14 505 0.1088100
GO:BP GO:0031032 actomyosin structure organization 5 187 0.1088100
GO:BP GO:0032204 regulation of telomere maintenance 7 97 0.1088100
GO:BP GO:0009303 rRNA transcription 4 37 0.1088100
GO:BP GO:0006605 protein targeting 2 312 0.1088100
GO:BP GO:0038166 angiotensin-activated signaling pathway 1 10 0.1088100
GO:BP GO:0043968 histone H2A acetylation 2 21 0.1088100
GO:BP GO:0090174 organelle membrane fusion 2 103 0.1088100
GO:BP GO:1902850 microtubule cytoskeleton organization involved in mitosis 7 158 0.1088100
GO:BP GO:1990116 ribosome-associated ubiquitin-dependent protein catabolic process 2 6 0.1088100
GO:BP GO:0090148 membrane fission 4 43 0.1088100
GO:BP GO:0033044 regulation of chromosome organization 14 236 0.1088100
GO:BP GO:0006625 protein targeting to peroxisome 1 19 0.1088100
GO:BP GO:0071763 nuclear membrane organization 5 43 0.1088100
GO:BP GO:0040029 epigenetic regulation of gene expression 4 182 0.1088100
GO:BP GO:0006884 cell volume homeostasis 3 25 0.1088100
GO:BP GO:0006906 vesicle fusion 2 101 0.1088100
GO:BP GO:0070256 negative regulation of mucus secretion 1 2 0.1088100
GO:BP GO:1990683 DNA double-strand break attachment to nuclear envelope 1 2 0.1088100
GO:BP GO:0032899 regulation of neurotrophin production 1 2 0.1088100
GO:BP GO:0098727 maintenance of cell number 6 153 0.1088100
GO:BP GO:0006891 intra-Golgi vesicle-mediated transport 3 33 0.1088100
GO:BP GO:1905515 non-motile cilium assembly 1 56 0.1095617
GO:BP GO:0006413 translational initiation 6 113 0.1095617
GO:BP GO:0002339 B cell selection 2 4 0.1095617
GO:BP GO:0000278 mitotic cell cycle 21 816 0.1095617
GO:BP GO:0009119 ribonucleoside metabolic process 1 23 0.1095617
GO:BP GO:0061197 fungiform papilla morphogenesis 1 4 0.1095617
GO:BP GO:0015919 peroxisomal membrane transport 1 20 0.1095617
GO:BP GO:0034660 ncRNA metabolic process 27 562 0.1095617
GO:BP GO:0000082 G1/S transition of mitotic cell cycle 11 206 0.1095617
GO:BP GO:0007017 microtubule-based process 3 759 0.1095962
GO:BP GO:0035732 nitric oxide storage 1 1 0.1095962
GO:BP GO:0110097 regulation of calcium import into the mitochondrion 1 2 0.1095962
GO:BP GO:0000819 sister chromatid segregation 13 217 0.1095962
GO:BP GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1 12 0.1095962
GO:BP GO:2000273 positive regulation of signaling receptor activity 2 33 0.1095962
GO:BP GO:0071478 cellular response to radiation 6 149 0.1095962
GO:BP GO:0090307 mitotic spindle assembly 1 69 0.1109746
GO:BP GO:0043574 peroxisomal transport 1 22 0.1116155
GO:BP GO:0032205 negative regulation of telomere maintenance 3 34 0.1116155
GO:BP GO:0016311 dephosphorylation 5 278 0.1116155
GO:BP GO:1905949 negative regulation of calcium ion import across plasma membrane 2 4 0.1116155
GO:BP GO:0036297 interstrand cross-link repair 3 36 0.1116155
GO:BP GO:1904505 regulation of telomere maintenance in response to DNA damage 3 17 0.1116155
GO:BP GO:1905168 positive regulation of double-strand break repair via homologous recombination 4 33 0.1116155
GO:BP GO:0034453 microtubule anchoring 1 24 0.1119508
GO:BP GO:0033554 cellular response to stress 19 1663 0.1137087
GO:BP GO:1901990 regulation of mitotic cell cycle phase transition 16 305 0.1137087
GO:BP GO:0014041 regulation of neuron maturation 2 6 0.1145916
GO:BP GO:1902117 positive regulation of organelle assembly 1 75 0.1145916
GO:BP GO:0045948 positive regulation of translational initiation 3 22 0.1145916
GO:BP GO:0070932 histone H3 deacetylation 1 6 0.1145916
GO:BP GO:0060831 smoothened signaling pathway involved in dorsal/ventral neural tube patterning 1 14 0.1145916
GO:BP GO:0080135 regulation of cellular response to stress 14 585 0.1145916
GO:BP GO:0061196 fungiform papilla development 1 5 0.1145916
GO:BP GO:0060789 hair follicle placode formation 1 5 0.1145916
GO:BP GO:1901796 regulation of signal transduction by p53 class mediator 5 101 0.1178069
GO:BP GO:0046329 negative regulation of JNK cascade 3 36 0.1196998
GO:BP GO:0007341 penetration of zona pellucida 1 4 0.1203858
GO:BP GO:1901523 icosanoid catabolic process 1 2 0.1203858
GO:BP GO:0051493 regulation of cytoskeleton organization 14 429 0.1216089
GO:BP GO:0031860 telomeric 3’ overhang formation 1 4 0.1219149
GO:BP GO:0006476 protein deacetylation 6 81 0.1220752
GO:BP GO:0097711 ciliary basal body-plasma membrane docking 1 1 0.1263107
GO:BP GO:0051146 striated muscle cell differentiation 5 239 0.1272256
GO:BP GO:0032933 SREBP signaling pathway 1 14 0.1272256
GO:BP GO:0000724 double-strand break repair via homologous recombination 9 155 0.1272256
GO:BP GO:1900453 negative regulation of long-term synaptic depression 1 3 0.1272256
GO:BP GO:0045654 positive regulation of megakaryocyte differentiation 1 9 0.1272256
GO:BP GO:0071985 multivesicular body sorting pathway 4 47 0.1273346
GO:BP GO:0051469 vesicle fusion with vacuole 2 11 0.1321321
GO:BP GO:0061763 multivesicular body-lysosome fusion 2 11 0.1321321
GO:BP GO:0071501 cellular response to sterol depletion 1 14 0.1321321
GO:BP GO:0048284 organelle fusion 2 133 0.1322348
GO:BP GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum 5 51 0.1334183
GO:BP GO:0006470 protein dephosphorylation 4 211 0.1350555
GO:BP GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway 1 2 0.1361341
GO:BP GO:0007031 peroxisome organization 1 34 0.1361341
GO:BP GO:0009116 nucleoside metabolic process 1 41 0.1361341
GO:BP GO:0000725 recombinational repair 9 159 0.1361341
GO:BP GO:1900864 mitochondrial RNA modification 2 9 0.1361341
GO:BP GO:1904385 cellular response to angiotensin 1 24 0.1361341
GO:BP GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway 3 27 0.1361341
GO:BP GO:0044743 protein transmembrane import into intracellular organelle 1 36 0.1361341
GO:BP GO:0021522 spinal cord motor neuron differentiation 2 17 0.1361341
GO:BP GO:2000036 regulation of stem cell population maintenance 6 63 0.1361341
GO:BP GO:0051102 DNA ligation involved in DNA recombination 1 1 0.1361341
GO:BP GO:0075713 establishment of integrated proviral latency 1 1 0.1361341
GO:BP GO:0010639 negative regulation of organelle organization 9 311 0.1361341
GO:BP GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity 1 4 0.1361341
GO:BP GO:0032968 positive regulation of transcription elongation by RNA polymerase II 5 48 0.1361341
GO:BP GO:0070900 mitochondrial tRNA modification 2 9 0.1361341
GO:BP GO:0006991 response to sterol depletion 1 16 0.1361341
GO:BP GO:0120034 positive regulation of plasma membrane bounded cell projection assembly 1 92 0.1361341
GO:BP GO:0042159 lipoprotein catabolic process 2 15 0.1361341
GO:BP GO:0001909 leukocyte mediated cytotoxicity 2 58 0.1362403
GO:BP GO:0090169 regulation of spindle assembly 3 32 0.1362403
GO:BP GO:0006997 nucleus organization 6 126 0.1362403
GO:BP GO:0071824 protein-DNA complex organization 30 713 0.1362403
GO:BP GO:0032049 cardiolipin biosynthetic process 2 7 0.1373550
GO:BP GO:0009304 tRNA transcription 2 9 0.1373550
GO:BP GO:0032938 negative regulation of translation in response to oxidative stress 1 1 0.1375007
GO:BP GO:0043556 regulation of translation in response to oxidative stress 1 1 0.1375007
GO:BP GO:0097576 vacuole fusion 2 12 0.1375007
GO:BP GO:0045214 sarcomere organization 2 42 0.1393988
GO:BP GO:0022402 cell cycle process 26 1080 0.1393988
GO:BP GO:0051276 chromosome organization 13 534 0.1399235
GO:BP GO:1905767 regulation of double-stranded telomeric DNA binding 1 1 0.1399235
GO:BP GO:1905768 negative regulation of double-stranded telomeric DNA binding 1 1 0.1399235
GO:BP GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c 2 7 0.1399235
GO:BP GO:1990776 response to angiotensin 1 25 0.1400550
GO:BP GO:0032898 neurotrophin production 1 4 0.1400550
GO:BP GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 1 2 0.1400550
GO:BP GO:0051225 spindle assembly 1 120 0.1400550
GO:BP GO:0110053 regulation of actin filament organization 2 224 0.1405167
GO:BP GO:0090398 cellular senescence 5 83 0.1405167
GO:BP GO:0000045 autophagosome assembly 7 100 0.1405167
GO:BP GO:0007052 mitotic spindle organization 1 128 0.1405167
GO:BP GO:0090312 positive regulation of protein deacetylation 3 21 0.1420162
GO:BP GO:0051664 nuclear pore localization 1 5 0.1443339
GO:BP GO:0060271 cilium assembly 2 296 0.1443339
GO:BP GO:0043587 tongue morphogenesis 1 7 0.1443339
GO:BP GO:0033131 regulation of glucokinase activity 2 7 0.1444713
GO:BP GO:0031338 regulation of vesicle fusion 1 17 0.1449396
GO:BP GO:0062033 positive regulation of mitotic sister chromatid segregation 2 6 0.1449396
GO:BP GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation 1 2 0.1449396
GO:BP GO:0061025 membrane fusion 2 132 0.1449396
GO:BP GO:0007033 vacuole organization 10 199 0.1449396
GO:BP GO:0006392 transcription elongation by mitochondrial RNA polymerase 1 1 0.1450065
GO:BP GO:0044772 mitotic cell cycle phase transition 19 411 0.1456733
GO:BP GO:0031400 negative regulation of protein modification process 12 396 0.1467858
GO:BP GO:0045905 positive regulation of translational termination 1 4 0.1468739
GO:BP GO:0070925 organelle assembly 31 830 0.1472182
GO:BP GO:0006384 transcription initiation at RNA polymerase III promoter 2 8 0.1472182
GO:BP GO:0021904 dorsal/ventral neural tube patterning 1 21 0.1472182
GO:BP GO:0080170 hydrogen peroxide transmembrane transport 1 1 0.1488927
GO:BP GO:0000056 ribosomal small subunit export from nucleus 2 8 0.1495629
GO:BP GO:0051129 negative regulation of cellular component organization 14 593 0.1495629
GO:BP GO:0006364 rRNA processing 12 215 0.1505370
GO:BP GO:0065002 intracellular protein transmembrane transport 1 53 0.1505370
GO:BP GO:1904572 negative regulation of mRNA binding 1 1 0.1505370
GO:BP GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 1 2 0.1505370
GO:BP GO:0007076 mitotic chromosome condensation 3 19 0.1505370
GO:BP GO:0044843 cell cycle G1/S phase transition 11 226 0.1505370
GO:BP GO:1904573 regulation of selenocysteine insertion sequence binding 1 1 0.1505370
GO:BP GO:0044782 cilium organization 2 317 0.1505370
GO:BP GO:0000723 telomere maintenance 9 142 0.1505370
GO:BP GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 2 12 0.1505370
GO:BP GO:0006281 DNA repair 25 543 0.1505370
GO:BP GO:1901657 glycosyl compound metabolic process 1 63 0.1505370
GO:BP GO:0048146 positive regulation of fibroblast proliferation 3 43 0.1505370
GO:BP GO:0032206 positive regulation of telomere maintenance 5 65 0.1505370
GO:BP GO:0072715 cellular response to selenite ion 1 1 0.1505370
GO:BP GO:0010616 negative regulation of cardiac muscle adaptation 1 6 0.1505370
GO:BP GO:0097212 lysosomal membrane organization 2 12 0.1505370
GO:BP GO:1904902 ESCRT III complex assembly 1 1 0.1505370
GO:BP GO:1904895 ESCRT complex assembly 1 1 0.1505370
GO:BP GO:1904574 negative regulation of selenocysteine insertion sequence binding 1 1 0.1505370
GO:BP GO:1904569 regulation of selenocysteine incorporation 1 1 0.1505370
GO:BP GO:0003271 smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation 1 1 0.1505370
GO:BP GO:0045910 negative regulation of DNA recombination 3 35 0.1505370
GO:BP GO:1903243 negative regulation of cardiac muscle hypertrophy in response to stress 1 6 0.1505370
GO:BP GO:0072714 response to selenite ion 1 1 0.1505370
GO:BP GO:1903299 regulation of hexokinase activity 2 8 0.1505370
GO:BP GO:1904570 negative regulation of selenocysteine incorporation 1 1 0.1505370
GO:BP GO:0048672 positive regulation of collateral sprouting 2 10 0.1505370
GO:BP GO:0016570 histone modification 12 270 0.1505370
GO:BP GO:1990497 regulation of cytoplasmic translation in response to stress 1 1 0.1515128
GO:BP GO:0032970 regulation of actin filament-based process 6 312 0.1515128
GO:BP GO:0050000 chromosome localization 5 101 0.1515128
GO:BP GO:1990611 regulation of cytoplasmic translational initiation in response to stress 1 1 0.1515128
GO:BP GO:0051496 positive regulation of stress fiber assembly 2 46 0.1529978
GO:BP GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway 1 2 0.1531741
GO:BP GO:0072331 signal transduction by p53 class mediator 6 162 0.1534447
GO:BP GO:2000042 negative regulation of double-strand break repair via homologous recombination 2 20 0.1534541
GO:BP GO:0032873 negative regulation of stress-activated MAPK cascade 3 46 0.1534541
GO:BP GO:1901569 fatty acid derivative catabolic process 1 10 0.1534541
GO:BP GO:0060788 ectodermal placode formation 1 10 0.1534541
GO:BP GO:1905673 positive regulation of lysosome organization 1 3 0.1534541
GO:BP GO:0071697 ectodermal placode morphogenesis 1 10 0.1534541
GO:BP GO:0061029 eyelid development in camera-type eye 1 11 0.1534541
GO:BP GO:0098795 global gene silencing by mRNA cleavage 1 3 0.1534922
GO:BP GO:1904668 positive regulation of ubiquitin protein ligase activity 2 12 0.1534922
GO:BP GO:1902229 regulation of intrinsic apoptotic signaling pathway in response to DNA damage 3 37 0.1534922
GO:BP GO:0006655 phosphatidylglycerol biosynthetic process 2 9 0.1539228
GO:BP GO:2001251 negative regulation of chromosome organization 4 90 0.1539228
GO:BP GO:0030952 establishment or maintenance of cytoskeleton polarity 1 7 0.1539228
GO:BP GO:0006378 mRNA polyadenylation 2 26 0.1539228
GO:BP GO:0001708 cell fate specification 2 55 0.1539228
GO:BP GO:0043201 response to leucine 2 13 0.1539228
GO:BP GO:0032956 regulation of actin cytoskeleton organization 2 271 0.1539228
GO:BP GO:0051348 negative regulation of transferase activity 8 225 0.1539228
GO:BP GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 2 18 0.1539228
GO:BP GO:0035019 somatic stem cell population maintenance 5 50 0.1539228
GO:BP GO:0120032 regulation of plasma membrane bounded cell projection assembly 1 163 0.1539228
GO:BP GO:0032229 negative regulation of synaptic transmission, GABAergic 1 3 0.1539228
GO:BP GO:0046761 viral budding from plasma membrane 2 13 0.1539228
GO:BP GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress 3 51 0.1539228
GO:BP GO:0060491 regulation of cell projection assembly 1 165 0.1539228
GO:BP GO:0072201 negative regulation of mesenchymal cell proliferation 1 7 0.1539228
GO:BP GO:0044087 regulation of cellular component biogenesis 3 802 0.1539228
GO:BP GO:0032241 positive regulation of nucleobase-containing compound transport 1 6 0.1539228
GO:BP GO:0014050 negative regulation of glutamate secretion 1 3 0.1539228
GO:BP GO:0070303 negative regulation of stress-activated protein kinase signaling cascade 3 47 0.1539228
GO:BP GO:0042748 circadian sleep/wake cycle, non-REM sleep 1 3 0.1539228
GO:BP GO:0007507 heart development 6 512 0.1539228
GO:BP GO:0071696 ectodermal placode development 1 11 0.1539228
GO:BP GO:0045210 FasL biosynthetic process 1 1 0.1539228
GO:BP GO:1905037 autophagosome organization 7 107 0.1539228
GO:BP GO:0009785 blue light signaling pathway 1 2 0.1548506
GO:BP GO:0071483 cellular response to blue light 1 2 0.1548506
GO:BP GO:0007051 spindle organization 1 189 0.1556824
GO:BP GO:0060173 limb development 2 141 0.1556824
GO:BP GO:0006289 nucleotide-excision repair 6 80 0.1556824
GO:BP GO:0071806 protein transmembrane transport 1 63 0.1556824
GO:BP GO:0048736 appendage development 2 141 0.1556824
GO:BP GO:1904195 regulation of granulosa cell proliferation 1 1 0.1564941
GO:BP GO:1904799 regulation of neuron remodeling 1 1 0.1564941
GO:BP GO:0060766 negative regulation of androgen receptor signaling pathway 1 12 0.1564941
GO:BP GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process 1 3 0.1564941
GO:BP GO:0008104 protein localization 4 2128 0.1564941
GO:BP GO:0031507 heterochromatin formation 2 75 0.1564941
GO:BP GO:1904800 negative regulation of neuron remodeling 1 1 0.1564941
GO:BP GO:0006606 protein import into nucleus 5 146 0.1564941
GO:BP GO:1902115 regulation of organelle assembly 1 189 0.1564941
GO:BP GO:0061015 snRNA import into nucleus 1 2 0.1564941
GO:BP GO:0035281 pre-miRNA export from nucleus 1 2 0.1564941
GO:BP GO:0008617 guanosine metabolic process 1 1 0.1564941
GO:BP GO:0032703 negative regulation of interleukin-2 production 2 10 0.1564941
GO:BP GO:0070727 cellular macromolecule localization 4 2137 0.1564941
GO:BP GO:1904197 positive regulation of granulosa cell proliferation 1 1 0.1564941
GO:BP GO:0043922 negative regulation by host of viral transcription 1 11 0.1564941
GO:BP GO:1901068 guanosine-containing compound metabolic process 1 1 0.1564941
GO:BP GO:2000173 negative regulation of branching morphogenesis of a nerve 1 1 0.1564941
GO:BP GO:1990739 granulosa cell proliferation 1 1 0.1564941
GO:BP GO:0010498 proteasomal protein catabolic process 20 481 0.1564941
GO:BP GO:0033484 intracellular nitric oxide homeostasis 1 3 0.1564941
GO:BP GO:0097191 extrinsic apoptotic signaling pathway 6 182 0.1569972
GO:BP GO:0046753 non-lytic viral release 2 14 0.1577353
GO:BP GO:0051983 regulation of chromosome segregation 8 121 0.1581493
GO:BP GO:0014745 negative regulation of muscle adaptation 1 8 0.1591396
GO:BP GO:0097240 chromosome attachment to the nuclear envelope 1 3 0.1591396
GO:BP GO:0006575 cellular modified amino acid metabolic process 1 93 0.1603920
GO:BP GO:0044182 filamentous growth of a population of unicellular organisms 1 1 0.1603920
GO:BP GO:0090199 regulation of release of cytochrome c from mitochondria 4 37 0.1603920
GO:BP GO:1900428 regulation of filamentous growth of a population of unicellular organisms 1 1 0.1603920
GO:BP GO:0043687 post-translational protein modification 12 1100 0.1603920
GO:BP GO:0140056 organelle localization by membrane tethering 3 69 0.1603920
GO:BP GO:0035304 regulation of protein dephosphorylation 2 72 0.1603920
GO:BP GO:1900221 regulation of amyloid-beta clearance 1 13 0.1603920
GO:BP GO:0006886 intracellular protein transport 2 805 0.1603920
GO:BP GO:0016925 protein sumoylation 5 60 0.1603920
GO:BP GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 1 9 0.1603920
GO:BP GO:0051170 import into nucleus 5 151 0.1603920
GO:BP GO:0021520 spinal cord motor neuron cell fate specification 1 5 0.1603920
GO:BP GO:0021532 neural tube patterning 1 31 0.1603920
GO:BP GO:1900430 positive regulation of filamentous growth of a population of unicellular organisms 1 1 0.1603920
GO:BP GO:1900461 positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter 1 1 0.1603920
GO:BP GO:0051246 regulation of protein metabolic process 42 1893 0.1603920
GO:BP GO:0090033 positive regulation of filamentous growth 1 1 0.1603920
GO:BP GO:1902903 regulation of supramolecular fiber organization 2 321 0.1603920
GO:BP GO:0043414 macromolecule methylation 12 238 0.1603920
GO:BP GO:0070786 positive regulation of growth of unicellular organism as a thread of attached cells 1 1 0.1603920
GO:BP GO:0003203 endocardial cushion morphogenesis 1 36 0.1603920
GO:BP GO:1990849 vacuolar localization 3 61 0.1603920
GO:BP GO:1990456 mitochondrion-endoplasmic reticulum membrane tethering 1 7 0.1603920
GO:BP GO:0061136 regulation of proteasomal protein catabolic process 2 179 0.1603920
GO:BP GO:0060236 regulation of mitotic spindle organization 3 42 0.1603920
GO:BP GO:0032233 positive regulation of actin filament bundle assembly 2 53 0.1603920
GO:BP GO:0030447 filamentous growth 1 1 0.1603920
GO:BP GO:0010570 regulation of filamentous growth 1 1 0.1603920
GO:BP GO:0007124 pseudohyphal growth 1 1 0.1603920
GO:BP GO:2000222 positive regulation of pseudohyphal growth 1 1 0.1603920
GO:BP GO:0010612 regulation of cardiac muscle adaptation 1 9 0.1603920
GO:BP GO:2000220 regulation of pseudohyphal growth 1 1 0.1603920
GO:BP GO:0090481 pyrimidine nucleotide-sugar transmembrane transport 2 12 0.1603920
GO:BP GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway 2 17 0.1603920
GO:BP GO:1901647 positive regulation of synoviocyte proliferation 1 3 0.1603920
GO:BP GO:0070784 regulation of growth of unicellular organism as a thread of attached cells 1 1 0.1603920
GO:BP GO:0032418 lysosome localization 3 61 0.1603920
GO:BP GO:0090646 mitochondrial tRNA processing 2 13 0.1603920
GO:BP GO:1901645 regulation of synoviocyte proliferation 1 3 0.1603920
GO:BP GO:0002941 synoviocyte proliferation 1 3 0.1603920
GO:BP GO:0070783 growth of unicellular organism as a thread of attached cells 1 1 0.1603920
GO:BP GO:0048511 rhythmic process 7 231 0.1603920
GO:BP GO:0009314 response to radiation 9 338 0.1603920
GO:BP GO:0046039 GTP metabolic process 3 20 0.1603920
GO:BP GO:0018205 peptidyl-lysine modification 12 286 0.1604407
GO:BP GO:0008608 attachment of spindle microtubules to kinetochore 2 42 0.1604407
GO:BP GO:0044092 negative regulation of molecular function 20 730 0.1604407
GO:BP GO:0015031 protein transport 29 1368 0.1604407
GO:BP GO:0032786 positive regulation of DNA-templated transcription, elongation 5 58 0.1604407
GO:BP GO:0000018 regulation of DNA recombination 7 103 0.1604407
GO:BP GO:2000781 positive regulation of double-strand break repair 6 79 0.1608806
GO:BP GO:1901255 nucleotide-excision repair involved in interstrand cross-link repair 1 2 0.1613488
GO:BP GO:1904743 negative regulation of telomeric DNA binding 1 2 0.1613488
GO:BP GO:0051656 establishment of organelle localization 10 397 0.1614187
GO:BP GO:0070828 heterochromatin organization 2 83 0.1614187
GO:BP GO:0072384 organelle transport along microtubule 1 83 0.1629970
GO:BP GO:0021527 spinal cord association neuron differentiation 1 3 0.1629970
GO:BP GO:0070255 regulation of mucus secretion 1 6 0.1629970
GO:BP GO:0042254 ribosome biogenesis 9 315 0.1657902
GO:BP GO:0021517 ventral spinal cord development 2 25 0.1657902
GO:BP GO:0051457 maintenance of protein location in nucleus 2 22 0.1660015
GO:BP GO:0072695 regulation of DNA recombination at telomere 1 2 0.1667980
GO:BP GO:0048239 negative regulation of DNA recombination at telomere 1 2 0.1667980
GO:BP GO:0008213 protein alkylation 1 125 0.1667980
GO:BP GO:0006479 protein methylation 1 125 0.1667980
GO:BP GO:0090241 negative regulation of histone H4 acetylation 1 1 0.1672396
GO:BP GO:0140014 mitotic nuclear division 8 251 0.1679100
GO:BP GO:0055015 ventricular cardiac muscle cell development 1 10 0.1682189
GO:BP GO:0051012 microtubule sliding 1 2 0.1682189
GO:BP GO:0060119 inner ear receptor cell development 3 33 0.1682189
GO:BP GO:0043586 tongue development 1 15 0.1682189
GO:BP GO:0044565 dendritic cell proliferation 1 3 0.1684101
GO:BP GO:0032091 negative regulation of protein binding 1 77 0.1684101
GO:BP GO:2000202 positive regulation of ribosomal subunit export from nucleus 1 1 0.1689207
GO:BP GO:0021514 ventral spinal cord interneuron differentiation 1 5 0.1689207
GO:BP GO:0015780 nucleotide-sugar transmembrane transport 2 13 0.1689207
GO:BP GO:1901685 glutathione derivative metabolic process 1 3 0.1689207
GO:BP GO:1901687 glutathione derivative biosynthetic process 1 3 0.1689207
GO:BP GO:2000208 positive regulation of ribosomal small subunit export from nucleus 1 1 0.1689207
GO:BP GO:2001234 negative regulation of apoptotic signaling pathway 7 200 0.1689207
GO:BP GO:2000206 regulation of ribosomal small subunit export from nucleus 1 1 0.1689207
GO:BP GO:2000200 regulation of ribosomal subunit export from nucleus 1 1 0.1689207
GO:BP GO:0035891 exit from host cell 3 28 0.1689207
GO:BP GO:2000199 positive regulation of ribonucleoprotein complex localization 1 1 0.1689207
GO:BP GO:2000626 negative regulation of miRNA catabolic process 1 1 0.1689207
GO:BP GO:1904886 beta-catenin destruction complex disassembly 1 4 0.1689207
GO:BP GO:0060261 positive regulation of transcription initiation by RNA polymerase II 5 60 0.1689207
GO:BP GO:0019076 viral release from host cell 3 28 0.1689207
GO:BP GO:0070898 RNA polymerase III preinitiation complex assembly 1 1 0.1689207
GO:BP GO:0036120 cellular response to platelet-derived growth factor stimulus 1 20 0.1689296
GO:BP GO:0015858 nucleoside transport 1 8 0.1696194
GO:BP GO:0003093 regulation of glomerular filtration 1 8 0.1696194
GO:BP GO:0051967 negative regulation of synaptic transmission, glutamatergic 1 6 0.1696194
GO:BP GO:0022406 membrane docking 2 79 0.1712066
GO:BP GO:0090224 regulation of spindle organization 3 45 0.1712066
GO:BP GO:0071482 cellular response to light stimulus 4 97 0.1713412
GO:BP GO:0045945 positive regulation of transcription by RNA polymerase III 2 19 0.1721869
GO:BP GO:0031167 rRNA methylation 3 24 0.1727909
GO:BP GO:0006351 DNA-templated transcription 67 2671 0.1729570
GO:BP GO:0061952 midbody abscission 2 17 0.1730341
GO:BP GO:0043124 negative regulation of canonical NF-kappaB signal transduction 3 37 0.1737613
GO:BP GO:0003197 endocardial cushion development 1 46 0.1737613
GO:BP GO:0006338 chromatin remodeling 21 522 0.1737613
GO:BP GO:0001906 cell killing 2 77 0.1737613
GO:BP GO:0032790 ribosome disassembly 2 13 0.1737613
GO:BP GO:0009953 dorsal/ventral pattern formation 2 56 0.1737613
GO:BP GO:0006984 ER-nucleus signaling pathway 1 44 0.1745258
GO:BP GO:0030239 myofibril assembly 2 66 0.1745258
GO:BP GO:0021515 cell differentiation in spinal cord 2 23 0.1745773
GO:BP GO:0098813 nuclear chromosome segregation 1 264 0.1745773
GO:BP GO:0140694 non-membrane-bounded organelle assembly 10 366 0.1752147
GO:BP GO:0045661 regulation of myoblast differentiation 5 60 0.1752147
GO:BP GO:0110012 protein localization to P-body 1 1 0.1752147
GO:BP GO:0120031 plasma membrane bounded cell projection assembly 2 463 0.1752147
GO:BP GO:0002334 transitional two stage B cell differentiation 1 1 0.1752147
GO:BP GO:0036119 response to platelet-derived growth factor 1 22 0.1753686
GO:BP GO:0071705 nitrogen compound transport 38 1692 0.1758015
GO:BP GO:0007220 Notch receptor processing 1 9 0.1758015
GO:BP GO:0042692 muscle cell differentiation 5 329 0.1780040
GO:BP GO:0014886 transition between slow and fast fiber 1 1 0.1780490
GO:BP GO:0000132 establishment of mitotic spindle orientation 3 32 0.1780490
GO:BP GO:1904613 cellular response to 2,3,7,8-tetrachlorodibenzodioxine 1 3 0.1780490
GO:BP GO:0030031 cell projection assembly 2 473 0.1781983
GO:BP GO:0045652 regulation of megakaryocyte differentiation 1 23 0.1785292
GO:BP GO:0048262 determination of dorsal/ventral asymmetry 1 6 0.1799928
GO:BP GO:0048193 Golgi vesicle transport 14 279 0.1799928
GO:BP GO:0010638 positive regulation of organelle organization 2 434 0.1799928
GO:BP GO:0002673 regulation of acute inflammatory response 2 22 0.1799928
GO:BP GO:0055002 striated muscle cell development 2 69 0.1799928
GO:BP GO:0008361 regulation of cell size 7 160 0.1799928
GO:BP GO:1990786 cellular response to dsDNA 1 2 0.1799928
GO:BP GO:0030490 maturation of SSU-rRNA 4 53 0.1799928
GO:BP GO:0019043 establishment of viral latency 1 3 0.1799928
GO:BP GO:1903050 regulation of proteolysis involved in protein catabolic process 2 210 0.1799928
GO:BP GO:0042275 error-free postreplication DNA repair 1 1 0.1799928
GO:BP GO:0044089 positive regulation of cellular component biogenesis 2 420 0.1799928
GO:BP GO:1905215 negative regulation of RNA binding 1 2 0.1799928
GO:BP GO:0009411 response to UV 8 140 0.1799928
GO:BP GO:1990784 response to dsDNA 1 2 0.1799928
GO:BP GO:0071264 positive regulation of translational initiation in response to starvation 1 2 0.1802887
GO:BP GO:0071262 regulation of translational initiation in response to starvation 1 2 0.1802887
GO:BP GO:0072132 mesenchyme morphogenesis 1 50 0.1802887
GO:BP GO:0006282 regulation of DNA repair 9 202 0.1811612
GO:BP GO:0031346 positive regulation of cell projection organization 1 301 0.1823089
GO:BP GO:0006465 signal peptide processing 2 13 0.1823089
GO:BP GO:0016485 protein processing 3 185 0.1823089
GO:BP GO:0060887 limb epidermis development 1 1 0.1823089
GO:BP GO:0007097 nuclear migration 2 23 0.1823089
GO:BP GO:0097352 autophagosome maturation 4 54 0.1823089
GO:BP GO:0032691 negative regulation of interleukin-1 beta production 2 13 0.1823089
GO:BP GO:0046464 acylglycerol catabolic process 1 22 0.1823089
GO:BP GO:0046461 neutral lipid catabolic process 1 22 0.1823089
GO:BP GO:0007015 actin filament organization 2 372 0.1823089
GO:BP GO:0043328 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 2 16 0.1823089
GO:BP GO:0048560 establishment of anatomical structure orientation 1 2 0.1823089
GO:BP GO:0033047 regulation of mitotic sister chromatid segregation 2 51 0.1831578
GO:BP GO:0048714 positive regulation of oligodendrocyte differentiation 1 13 0.1831578
GO:BP GO:1904637 cellular response to ionomycin 1 3 0.1846708
GO:BP GO:0060058 positive regulation of apoptotic process involved in mammary gland involution 1 3 0.1846708
GO:BP GO:0060057 apoptotic process involved in mammary gland involution 1 3 0.1846708
GO:BP GO:0033762 response to glucagon 2 14 0.1846708
GO:BP GO:0045727 positive regulation of translation 6 127 0.1846708
GO:BP GO:0051310 metaphase chromosome alignment 4 87 0.1846708
GO:BP GO:0010823 negative regulation of mitochondrion organization 4 45 0.1846708
GO:BP GO:1904636 response to ionomycin 1 3 0.1846708
GO:BP GO:0006449 regulation of translational termination 1 10 0.1846708
GO:BP GO:0032774 RNA biosynthetic process 67 2701 0.1880232
GO:BP GO:0033036 macromolecule localization 4 2446 0.1884188
GO:BP GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway 2 30 0.1884188
GO:BP GO:1901991 negative regulation of mitotic cell cycle phase transition 9 165 0.1884283
GO:BP GO:0021508 floor plate formation 1 3 0.1888782
GO:BP GO:0090435 protein localization to nuclear envelope 1 14 0.1888964
GO:BP GO:0060765 regulation of androgen receptor signaling pathway 1 24 0.1888964
GO:BP GO:0061819 telomeric DNA-containing double minutes formation 1 3 0.1888964
GO:BP GO:2000134 negative regulation of G1/S transition of mitotic cell cycle 3 64 0.1888964
GO:BP GO:0062196 regulation of lysosome size 1 8 0.1888964
GO:BP GO:0016197 endosomal transport 12 232 0.1888964
GO:BP GO:1905765 negative regulation of protection from non-homologous end joining at telomere 1 3 0.1888964
GO:BP GO:0021915 neural tube development 2 143 0.1888964
GO:BP GO:1905764 regulation of protection from non-homologous end joining at telomere 1 3 0.1888964
GO:BP GO:1905665 positive regulation of calcium ion import across plasma membrane 2 6 0.1888964
GO:BP GO:0035588 G protein-coupled purinergic receptor signaling pathway 1 7 0.1897216
GO:BP GO:0001973 G protein-coupled adenosine receptor signaling pathway 1 7 0.1897216
GO:BP GO:1900272 negative regulation of long-term synaptic potentiation 1 9 0.1897216
GO:BP GO:2000847 negative regulation of corticosteroid hormone secretion 1 4 0.1910116
GO:BP GO:2000832 negative regulation of steroid hormone secretion 1 4 0.1910116
GO:BP GO:2000850 negative regulation of glucocorticoid secretion 1 4 0.1910116
GO:BP GO:1905671 regulation of lysosome organization 1 8 0.1910427
GO:BP GO:2000780 negative regulation of double-strand break repair 2 32 0.1910427
GO:BP GO:0035621 ER to Golgi ceramide transport 1 4 0.1910427
GO:BP GO:0008589 regulation of smoothened signaling pathway 2 72 0.1910427
GO:BP GO:0071901 negative regulation of protein serine/threonine kinase activity 4 96 0.1910427
GO:BP GO:0001915 negative regulation of T cell mediated cytotoxicity 1 3 0.1910427
GO:BP GO:0036211 protein modification process 25 2752 0.1914946
GO:BP GO:0031547 brain-derived neurotrophic factor receptor signaling pathway 1 6 0.1923882
GO:BP GO:0071214 cellular response to abiotic stimulus 7 259 0.1923882
GO:BP GO:1905281 positive regulation of retrograde transport, endosome to Golgi 1 2 0.1923882
GO:BP GO:0104004 cellular response to environmental stimulus 7 259 0.1923882
GO:BP GO:1904357 negative regulation of telomere maintenance via telomere lengthening 2 27 0.1923882
GO:BP GO:0034504 protein localization to nucleus 7 282 0.1923882
GO:BP GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 3 41 0.1923882
GO:BP GO:0031503 protein-containing complex localization 5 166 0.1923882
GO:BP GO:2000144 positive regulation of DNA-templated transcription initiation 5 66 0.1924619
GO:BP GO:0031399 regulation of protein modification process 26 1094 0.1927663
GO:BP GO:0007059 chromosome segregation 1 361 0.1932897
GO:BP GO:0034470 ncRNA processing 18 398 0.1933030
GO:BP GO:0055012 ventricular cardiac muscle cell differentiation 1 15 0.1933030
GO:BP GO:0090176 microtubule cytoskeleton organization involved in establishment of planar polarity 1 3 0.1936594
GO:BP GO:0048521 negative regulation of behavior 1 6 0.1941564
GO:BP GO:0061912 selective autophagy 3 92 0.1941564
GO:BP GO:0003084 positive regulation of systemic arterial blood pressure 1 7 0.1941564
GO:BP GO:0032460 negative regulation of protein oligomerization 1 2 0.1941564
GO:BP GO:0032463 negative regulation of protein homooligomerization 1 2 0.1941564
GO:BP GO:0002087 regulation of respiratory gaseous exchange by nervous system process 1 8 0.1941564
GO:BP GO:0045741 positive regulation of epidermal growth factor-activated receptor activity 1 8 0.1941564
GO:BP GO:1901605 alpha-amino acid metabolic process 1 151 0.1941564
GO:BP GO:0005981 regulation of glycogen catabolic process 1 5 0.1941564
GO:BP GO:0016239 positive regulation of macroautophagy 3 70 0.1943483
GO:BP GO:0071638 negative regulation of monocyte chemotactic protein-1 production 1 3 0.1943483
GO:BP GO:1904888 cranial skeletal system development 1 51 0.1943483
GO:BP GO:0036444 calcium import into the mitochondrion 1 12 0.1943483
GO:BP GO:0006404 RNA import into nucleus 1 4 0.1943483
GO:BP GO:0048208 COPII vesicle coating 1 24 0.1959728
GO:BP GO:0000280 nuclear division 1 343 0.1959728
GO:BP GO:0021516 dorsal spinal cord development 1 7 0.1959728
GO:BP GO:0034614 cellular response to reactive oxygen species 1 125 0.1959728
GO:BP GO:0034486 vacuolar transmembrane transport 1 3 0.1959728
GO:BP GO:0034141 positive regulation of toll-like receptor 3 signaling pathway 1 7 0.1959728
GO:BP GO:1902774 late endosome to lysosome transport 2 20 0.1959728
GO:BP GO:0048207 vesicle targeting, rough ER to cis-Golgi 1 24 0.1959728
GO:BP GO:2001235 positive regulation of apoptotic signaling pathway 5 113 0.1959728
GO:BP GO:1904155 DN2 thymocyte differentiation 1 1 0.1974401
GO:BP GO:0033153 T cell receptor V(D)J recombination 1 3 0.1974401
GO:BP GO:0106217 tRNA C3-cytosine methylation 1 2 0.1974401
GO:BP GO:0032200 telomere organization 8 156 0.1974401
GO:BP GO:0019042 viral latency 1 4 0.1974401
GO:BP GO:0002681 somatic recombination of T cell receptor gene segments 1 3 0.1974401
GO:BP GO:0002568 somatic diversification of T cell receptor genes 1 3 0.1974401
GO:BP GO:0045738 negative regulation of DNA repair 2 34 0.1974401
GO:BP GO:0006346 DNA methylation-dependent heterochromatin formation 1 22 0.1974401
GO:BP GO:0007224 smoothened signaling pathway 7 123 0.1979427
GO:BP GO:0047496 vesicle transport along microtubule 3 42 0.1979427
GO:BP GO:0070254 mucus secretion 1 8 0.1979427
GO:BP GO:0001977 renal system process involved in regulation of blood volume 1 8 0.1979427
GO:BP GO:0033045 regulation of sister chromatid segregation 6 99 0.1979427
GO:BP GO:1905691 lipid droplet disassembly 1 7 0.1979427
GO:BP GO:0080009 mRNA methylation 2 18 0.1979427
GO:BP GO:0051123 RNA polymerase II preinitiation complex assembly 5 54 0.1979427
GO:BP GO:0072334 UDP-galactose transmembrane transport 1 3 0.1979427
GO:BP GO:0051248 negative regulation of protein metabolic process 19 799 0.1979427
GO:BP GO:0051984 positive regulation of chromosome segregation 3 27 0.1979427
GO:BP GO:1901985 positive regulation of protein acetylation 2 29 0.1979427
GO:BP GO:1904293 negative regulation of ERAD pathway 1 6 0.1979427
GO:BP GO:0000054 ribosomal subunit export from nucleus 2 14 0.1984388
GO:BP GO:0033750 ribosome localization 2 14 0.1984388
GO:BP GO:2000210 positive regulation of anoikis 1 6 0.1985636
GO:BP GO:1904507 positive regulation of telomere maintenance in response to DNA damage 2 14 0.1985636
GO:BP GO:0006469 negative regulation of protein kinase activity 6 173 0.1985636
GO:BP GO:0043412 macromolecule modification 26 2949 0.1985636
GO:BP GO:1904780 negative regulation of protein localization to centrosome 1 2 0.1985636
GO:BP GO:0007080 mitotic metaphase chromosome alignment 3 55 0.1985636
GO:BP GO:1900122 positive regulation of receptor binding 1 7 0.1987404
GO:BP GO:0001836 release of cytochrome c from mitochondria 4 46 0.1988759
GO:BP GO:0046600 negative regulation of centriole replication 1 7 0.1989293
GO:BP GO:0045931 positive regulation of mitotic cell cycle 5 111 0.1989293
GO:BP GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity 2 24 0.1989293
GO:BP GO:0051100 negative regulation of binding 1 133 0.1989293
GO:BP GO:0050893 sensory processing 1 4 0.1989620
GO:BP GO:1902807 negative regulation of cell cycle G1/S phase transition 3 68 0.1991743
GO:BP GO:0010212 response to ionizing radiation 4 127 0.1992926
GO:BP GO:0022616 DNA strand elongation 3 35 0.2001309
GO:BP GO:0051128 regulation of cellular component organization 4 1981 0.2001309
GO:BP GO:0032048 cardiolipin metabolic process 2 13 0.2001309
GO:BP GO:1901875 positive regulation of post-translational protein modification 8 169 0.2001309
GO:BP GO:0008045 motor neuron axon guidance 2 19 0.2001309
GO:BP GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation 1 2 0.2009307
GO:BP GO:0031987 locomotion involved in locomotory behavior 1 10 0.2011028
GO:BP GO:1900452 regulation of long-term synaptic depression 1 11 0.2011028
GO:BP GO:0048285 organelle fission 1 388 0.2011028
GO:BP GO:0099509 regulation of presynaptic cytosolic calcium ion concentration 1 9 0.2011028
GO:BP GO:0040001 establishment of mitotic spindle localization 3 37 0.2011028
GO:BP GO:0030162 regulation of proteolysis 3 522 0.2011028
GO:BP GO:0032239 regulation of nucleobase-containing compound transport 1 15 0.2011028
GO:BP GO:0045187 regulation of circadian sleep/wake cycle, sleep 1 8 0.2011028
GO:BP GO:0090235 regulation of metaphase plate congression 2 13 0.2011028
GO:BP GO:0018872 arsonoacetate metabolic process 1 1 0.2014636
GO:BP GO:0032775 DNA methylation on adenine 1 2 0.2014636
GO:BP GO:2001236 regulation of extrinsic apoptotic signaling pathway 5 124 0.2018220
GO:BP GO:0035303 regulation of dephosphorylation 2 102 0.2018220
GO:BP GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus 3 19 0.2018220
GO:BP GO:0006399 tRNA metabolic process 9 190 0.2019888
GO:BP GO:0010803 regulation of tumor necrosis factor-mediated signaling pathway 3 45 0.2024837
GO:BP GO:0006310 DNA recombination 12 262 0.2024837
GO:BP GO:0099547 regulation of translation at synapse, modulating synaptic transmission 1 3 0.2024903
GO:BP GO:0099578 regulation of translation at postsynapse, modulating synaptic transmission 1 3 0.2024903
GO:BP GO:0043407 negative regulation of MAP kinase activity 2 50 0.2024903
GO:BP GO:1904030 negative regulation of cyclin-dependent protein kinase activity 2 25 0.2027816
GO:BP GO:0032692 negative regulation of interleukin-1 production 2 15 0.2030912
GO:BP GO:0045184 establishment of protein localization 13 1470 0.2030912
GO:BP GO:0033505 floor plate morphogenesis 1 3 0.2030912
GO:BP GO:0010970 transport along microtubule 1 162 0.2030912
GO:BP GO:0071353 cellular response to interleukin-4 2 23 0.2030912
GO:BP GO:0070525 tRNA threonylcarbamoyladenosine metabolic process 2 16 0.2030912
GO:BP GO:0006913 nucleocytoplasmic transport 13 294 0.2034188
GO:BP GO:1904742 regulation of telomeric DNA binding 1 4 0.2034188
GO:BP GO:1904506 negative regulation of telomere maintenance in response to DNA damage 1 3 0.2034188
GO:BP GO:0097242 amyloid-beta clearance 1 27 0.2034188
GO:BP GO:0051169 nuclear transport 13 294 0.2034188
GO:BP GO:0051294 establishment of spindle orientation 3 37 0.2034902
GO:BP GO:0001933 negative regulation of protein phosphorylation 8 265 0.2034902
GO:BP GO:0051438 regulation of ubiquitin-protein transferase activity 3 51 0.2034902
GO:BP GO:0043433 negative regulation of DNA-binding transcription factor activity 1 136 0.2038302
GO:BP GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway 2 17 0.2038302
GO:BP GO:0051956 negative regulation of amino acid transport 1 11 0.2038302
GO:BP GO:0055089 fatty acid homeostasis 1 12 0.2038302
GO:BP GO:1902425 positive regulation of attachment of mitotic spindle microtubules to kinetochore 1 8 0.2038302
GO:BP GO:1902423 regulation of attachment of mitotic spindle microtubules to kinetochore 1 8 0.2038302
GO:BP GO:0044065 regulation of respiratory system process 1 11 0.2038302
GO:BP GO:0050802 circadian sleep/wake cycle, sleep 1 9 0.2038302
GO:BP GO:0002449 lymphocyte mediated immunity 2 147 0.2038302
GO:BP GO:2000045 regulation of G1/S transition of mitotic cell cycle 7 146 0.2042930
GO:BP GO:0032957 inositol trisphosphate metabolic process 1 10 0.2042930
GO:BP GO:1905786 positive regulation of anaphase-promoting complex-dependent catabolic process 1 2 0.2042930
GO:BP GO:0009992 intracellular water homeostasis 1 3 0.2042930
GO:BP GO:0015793 glycerol transmembrane transport 1 4 0.2042930
GO:BP GO:1905365 regulation of intralumenal vesicle formation 1 2 0.2048161
GO:BP GO:1904979 negative regulation of endosome organization 1 2 0.2048161
GO:BP GO:0007174 epidermal growth factor catabolic process 1 2 0.2048161
GO:BP GO:0035720 intraciliary anterograde transport 2 18 0.2048161
GO:BP GO:0042157 lipoprotein metabolic process 2 116 0.2048161
GO:BP GO:0031065 positive regulation of histone deacetylation 2 15 0.2048161
GO:BP GO:1905664 regulation of calcium ion import across plasma membrane 2 8 0.2048161
GO:BP GO:0140157 ammonium import across plasma membrane 1 3 0.2048161
GO:BP GO:1905366 negative regulation of intralumenal vesicle formation 1 2 0.2048161
GO:BP GO:0051571 positive regulation of histone H3-K4 methylation 2 15 0.2049567
GO:BP GO:0099022 vesicle tethering 1 32 0.2049567
GO:BP GO:0051338 regulation of transferase activity 17 663 0.2049567
GO:BP GO:0097435 supramolecular fiber organization 7 666 0.2049567
GO:BP GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 2 36 0.2049567
GO:BP GO:1904612 response to 2,3,7,8-tetrachlorodibenzodioxine 1 4 0.2057090
GO:BP GO:0034139 regulation of toll-like receptor 3 signaling pathway 1 9 0.2057090
GO:BP GO:0098876 vesicle-mediated transport to the plasma membrane 8 140 0.2057090
GO:BP GO:0070922 RISC complex assembly 1 9 0.2057090
GO:BP GO:0070198 protein localization to chromosome, telomeric region 2 30 0.2057090
GO:BP GO:0098693 regulation of synaptic vesicle cycle 2 13 0.2071142
GO:BP GO:0043506 regulation of JUN kinase activity 2 50 0.2071142
GO:BP GO:0080171 lytic vacuole organization 4 90 0.2071785
GO:BP GO:0033059 cellular pigmentation 4 58 0.2071785
GO:BP GO:1903429 regulation of cell maturation 2 13 0.2071785
GO:BP GO:0007040 lysosome organization 4 90 0.2071785
GO:BP GO:0000963 mitochondrial RNA processing 2 20 0.2071785
GO:BP GO:0006043 glucosamine catabolic process 1 2 0.2071785
GO:BP GO:0043622 cortical microtubule organization 1 4 0.2071785
GO:BP GO:0051303 establishment of chromosome localization 4 93 0.2071785
GO:BP GO:0048199 vesicle targeting, to, from or within Golgi 1 31 0.2071785
GO:BP GO:0006297 nucleotide-excision repair, DNA gap filling 1 5 0.2073726
GO:BP GO:0051103 DNA ligation involved in DNA repair 1 5 0.2073726
GO:BP GO:0051877 pigment granule aggregation in cell center 1 2 0.2076697
GO:BP GO:1903929 primary palate development 1 2 0.2076697
GO:BP GO:0070670 response to interleukin-4 2 24 0.2083894
GO:BP GO:0010835 regulation of protein ADP-ribosylation 1 9 0.2092513
GO:BP GO:0051122 hepoxilin biosynthetic process 1 4 0.2092513
GO:BP GO:0051121 hepoxilin metabolic process 1 4 0.2092513
GO:BP GO:0051490 negative regulation of filopodium assembly 1 6 0.2092513
GO:BP GO:0045739 positive regulation of DNA repair 7 121 0.2101072
GO:BP GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 3 85 0.2101072
GO:BP GO:0070507 regulation of microtubule cytoskeleton organization 5 145 0.2104035
GO:BP GO:0007019 microtubule depolymerization 2 41 0.2104035
GO:BP GO:0030219 megakaryocyte differentiation 1 44 0.2108493
GO:BP GO:0007023 post-chaperonin tubulin folding pathway 1 7 0.2115734
GO:BP GO:0035082 axoneme assembly 1 54 0.2115734
GO:BP GO:0060113 inner ear receptor cell differentiation 3 46 0.2120498
GO:BP GO:0000302 response to reactive oxygen species 1 163 0.2120498
GO:BP GO:0060382 regulation of DNA strand elongation 2 16 0.2120498
GO:BP GO:0015931 nucleobase-containing compound transport 8 194 0.2120498
GO:BP GO:0050965 detection of temperature stimulus involved in sensory perception of pain 1 9 0.2120498
GO:BP GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 17 0.2120498
GO:BP GO:0006427 histidyl-tRNA aminoacylation 1 2 0.2124872
GO:BP GO:1902389 ceramide 1-phosphate transport 1 6 0.2127073
GO:BP GO:1902065 response to L-glutamate 2 11 0.2127073
GO:BP GO:0045687 positive regulation of glial cell differentiation 1 28 0.2127073
GO:BP GO:0060155 platelet dense granule organization 2 24 0.2127073
GO:BP GO:0018394 peptidyl-lysine acetylation 6 126 0.2127073
GO:BP GO:0021895 cerebral cortex neuron differentiation 2 14 0.2127073
GO:BP GO:0051641 cellular localization 4 2819 0.2127073
GO:BP GO:0009637 response to blue light 1 3 0.2127073
GO:BP GO:0032364 intracellular oxygen homeostasis 1 7 0.2127073
GO:BP GO:1903894 regulation of IRE1-mediated unfolded protein response 2 14 0.2127073
GO:BP GO:1904666 regulation of ubiquitin protein ligase activity 2 22 0.2127073
GO:BP GO:0051647 nucleus localization 2 30 0.2127073
GO:BP GO:0006520 amino acid metabolic process 1 222 0.2127073
GO:BP GO:0003299 muscle hypertrophy in response to stress 1 22 0.2127073
GO:BP GO:0048670 regulation of collateral sprouting 2 19 0.2127073
GO:BP GO:0045911 positive regulation of DNA recombination 2 56 0.2127073
GO:BP GO:0043393 regulation of protein binding 1 173 0.2127073
GO:BP GO:0031124 mRNA 3’-end processing 2 50 0.2127073
GO:BP GO:0014887 cardiac muscle adaptation 1 22 0.2127073
GO:BP GO:0048713 regulation of oligodendrocyte differentiation 1 25 0.2127073
GO:BP GO:2000323 negative regulation of glucocorticoid receptor signaling pathway 1 5 0.2127073
GO:BP GO:1901701 cellular response to oxygen-containing compound 2 892 0.2127073
GO:BP GO:0014898 cardiac muscle hypertrophy in response to stress 1 22 0.2127073
GO:BP GO:0051603 proteolysis involved in protein catabolic process 28 712 0.2127073
GO:BP GO:0002352 B cell negative selection 1 2 0.2127073
GO:BP GO:0006325 chromatin organization 23 633 0.2127863
GO:BP GO:0032057 negative regulation of translational initiation in response to stress 1 5 0.2129686
GO:BP GO:1904353 regulation of telomere capping 2 23 0.2129686
GO:BP GO:0032055 negative regulation of translation in response to stress 1 5 0.2129686
GO:BP GO:0022410 circadian sleep/wake cycle process 1 10 0.2142057
GO:BP GO:0042749 regulation of circadian sleep/wake cycle 1 10 0.2142057
GO:BP GO:0046503 glycerolipid catabolic process 1 39 0.2143351
GO:BP GO:0140718 facultative heterochromatin formation 1 35 0.2143351
GO:BP GO:0006415 translational termination 1 17 0.2143351
GO:BP GO:0030705 cytoskeleton-dependent intracellular transport 1 195 0.2143351
GO:BP GO:0010469 regulation of signaling receptor activity 2 97 0.2146812
GO:BP GO:0072666 establishment of protein localization to vacuole 4 56 0.2153167
GO:BP GO:0014043 negative regulation of neuron maturation 1 2 0.2153167
GO:BP GO:0099111 microtubule-based transport 1 192 0.2153167
GO:BP GO:0002332 transitional stage B cell differentiation 1 2 0.2153167
GO:BP GO:1903008 organelle disassembly 7 141 0.2153167
GO:BP GO:1902410 mitotic cytokinetic process 2 26 0.2153167
GO:BP GO:0006790 sulfur compound metabolic process 1 248 0.2153167
GO:BP GO:0051036 regulation of endosome size 1 13 0.2153167
GO:BP GO:0008637 apoptotic mitochondrial changes 3 90 0.2154854
GO:BP GO:0006170 dAMP biosynthetic process 1 3 0.2162919
GO:BP GO:0106383 dAMP salvage 1 3 0.2162919
GO:BP GO:0009171 purine deoxyribonucleoside monophosphate biosynthetic process 1 3 0.2162919
GO:BP GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 4 94 0.2162919
GO:BP GO:0106381 purine deoxyribonucleotide salvage 1 3 0.2162919
GO:BP GO:0051030 snRNA transport 1 6 0.2162919
GO:BP GO:0035726 common myeloid progenitor cell proliferation 1 6 0.2162919
GO:BP GO:0032259 methylation 1 286 0.2162919
GO:BP GO:0046070 dGTP metabolic process 1 3 0.2162919
GO:BP GO:0120035 regulation of plasma membrane bounded cell projection organization 1 528 0.2166495
GO:BP GO:0046907 intracellular transport 2 1439 0.2167838
GO:BP GO:0044778 meiotic DNA integrity checkpoint signaling 1 1 0.2169797
GO:BP GO:0014048 regulation of glutamate secretion 1 9 0.2178722
GO:BP GO:0000012 single strand break repair 2 10 0.2181396
GO:BP GO:0006901 vesicle coating 1 36 0.2183342
GO:BP GO:0030091 protein repair 1 7 0.2190638
GO:BP GO:0031344 regulation of cell projection organization 1 541 0.2195881
GO:BP GO:0000154 rRNA modification 3 33 0.2195881
GO:BP GO:0033344 cholesterol efflux 1 41 0.2195881
GO:BP GO:0010508 positive regulation of autophagy 4 134 0.2195881
GO:BP GO:0000959 mitochondrial RNA metabolic process 3 51 0.2195881
GO:BP GO:1904356 regulation of telomere maintenance via telomere lengthening 3 57 0.2195881
GO:BP GO:0097680 double-strand break repair via classical nonhomologous end joining 1 6 0.2212436
GO:BP GO:1905857 positive regulation of pentose-phosphate shunt 1 4 0.2212436
GO:BP GO:0051569 regulation of histone H3-K4 methylation 2 17 0.2213770
GO:BP GO:0009416 response to light stimulus 9 240 0.2214044
GO:BP GO:0006851 mitochondrial calcium ion transmembrane transport 1 18 0.2218637
GO:BP GO:0030521 androgen receptor signaling pathway 1 41 0.2220847
GO:BP GO:0048147 negative regulation of fibroblast proliferation 2 31 0.2220847
GO:BP GO:0006414 translational elongation 4 71 0.2220847
GO:BP GO:0039534 negative regulation of MDA-5 signaling pathway 1 3 0.2227029
GO:BP GO:0032058 positive regulation of translational initiation in response to stress 1 4 0.2227029
GO:BP GO:2000279 negative regulation of DNA biosynthetic process 2 34 0.2227029
GO:BP GO:0051930 regulation of sensory perception of pain 1 8 0.2227029
GO:BP GO:0042745 circadian sleep/wake cycle 1 11 0.2227029
GO:BP GO:0140469 GCN2-mediated signaling 1 4 0.2227029
GO:BP GO:0051931 regulation of sensory perception 1 8 0.2227029
GO:BP GO:2000322 regulation of glucocorticoid receptor signaling pathway 1 6 0.2244009
GO:BP GO:0031397 negative regulation of protein ubiquitination 3 76 0.2244384
GO:BP GO:0031333 negative regulation of protein-containing complex assembly 2 125 0.2244384
GO:BP GO:0051489 regulation of filopodium assembly 2 44 0.2245812
GO:BP GO:0046604 positive regulation of mitotic centrosome separation 1 3 0.2249941
GO:BP GO:0033673 negative regulation of kinase activity 6 191 0.2251900
GO:BP GO:0034644 cellular response to UV 3 85 0.2251900
GO:BP GO:1902174 positive regulation of keratinocyte apoptotic process 1 3 0.2251900
GO:BP GO:0090387 phagolysosome assembly involved in apoptotic cell clearance 1 2 0.2251900
GO:BP GO:0006612 protein targeting to membrane 1 122 0.2251900
GO:BP GO:0046836 glycolipid transport 1 7 0.2251900
GO:BP GO:0009628 response to abiotic stimulus 10 847 0.2251900
GO:BP GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 1 10 0.2251900
GO:BP GO:0042490 mechanoreceptor differentiation 3 48 0.2251900
GO:BP GO:0090386 phagosome maturation involved in apoptotic cell clearance 1 2 0.2251900
GO:BP GO:2000479 regulation of cAMP-dependent protein kinase activity 2 14 0.2254189
GO:BP GO:0033363 secretory granule organization 3 51 0.2256461
GO:BP GO:0030431 sleep 1 10 0.2256461
GO:BP GO:0003085 negative regulation of systemic arterial blood pressure 1 14 0.2256461
GO:BP GO:0002793 positive regulation of peptide secretion 2 73 0.2256461
GO:BP GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore 1 11 0.2256461
GO:BP GO:0007176 regulation of epidermal growth factor-activated receptor activity 2 24 0.2256461
GO:BP GO:0001881 receptor recycling 3 43 0.2256461
GO:BP GO:0098801 regulation of renal system process 1 16 0.2256461
GO:BP GO:0050961 detection of temperature stimulus involved in sensory perception 1 11 0.2256461
GO:BP GO:0001778 plasma membrane repair 2 27 0.2256461
GO:BP GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 17 420 0.2256461
GO:BP GO:0032515 negative regulation of phosphoprotein phosphatase activity 1 20 0.2256461
GO:BP GO:0090114 COPII-coated vesicle budding 1 40 0.2262648
GO:BP GO:2000642 negative regulation of early endosome to late endosome transport 1 2 0.2262933
GO:BP GO:1902339 positive regulation of apoptotic process involved in morphogenesis 1 5 0.2273843
GO:BP GO:0006432 phenylalanyl-tRNA aminoacylation 1 4 0.2273843
GO:BP GO:0048278 vesicle docking 1 54 0.2273843
GO:BP GO:0071362 cellular response to ether 1 5 0.2273843
GO:BP GO:0019083 viral transcription 1 48 0.2273843
GO:BP GO:1904747 positive regulation of apoptotic process involved in development 1 5 0.2273843
GO:BP GO:0034599 cellular response to oxidative stress 1 217 0.2273843
GO:BP GO:0030578 PML body organization 1 6 0.2273843
GO:BP GO:0009894 regulation of catabolic process 19 883 0.2273843
GO:BP GO:0090402 oncogene-induced cell senescence 1 5 0.2273843
GO:BP GO:0008217 regulation of blood pressure 1 114 0.2273843
GO:BP GO:2000736 regulation of stem cell differentiation 2 71 0.2273843
GO:BP GO:0097485 neuron projection guidance 2 177 0.2276166
GO:BP GO:0001736 establishment of planar polarity 3 70 0.2276166
GO:BP GO:0099179 regulation of synaptic membrane adhesion 1 4 0.2276166
GO:BP GO:0000055 ribosomal large subunit export from nucleus 1 7 0.2276166
GO:BP GO:0051252 regulation of RNA metabolic process 68 2826 0.2276166
GO:BP GO:1901387 positive regulation of voltage-gated calcium channel activity 1 12 0.2276166
GO:BP GO:0048665 neuron fate specification 1 13 0.2276166
GO:BP GO:1901568 fatty acid derivative metabolic process 1 49 0.2276166
GO:BP GO:0015791 polyol transmembrane transport 1 6 0.2276166
GO:BP GO:0001578 microtubule bundle formation 1 79 0.2276166
GO:BP GO:0001946 lymphangiogenesis 1 12 0.2276166
GO:BP GO:0030036 actin cytoskeleton organization 2 566 0.2276166
GO:BP GO:0007030 Golgi organization 1 133 0.2276166
GO:BP GO:0010614 negative regulation of cardiac muscle hypertrophy 1 25 0.2276166
GO:BP GO:0034244 negative regulation of transcription elongation by RNA polymerase II 2 18 0.2276166
GO:BP GO:0034250 positive regulation of amide metabolic process 6 150 0.2276166
GO:BP GO:1902661 positive regulation of glucose mediated signaling pathway 1 3 0.2276166
GO:BP GO:0045663 positive regulation of myoblast differentiation 3 36 0.2276166
GO:BP GO:1902659 regulation of glucose mediated signaling pathway 1 3 0.2276166
GO:BP GO:0035434 copper ion transmembrane transport 1 7 0.2276166
GO:BP GO:0006359 regulation of transcription by RNA polymerase III 2 30 0.2276166
GO:BP GO:0007418 ventral midline development 1 4 0.2276166
GO:BP GO:0042256 cytosolic ribosome assembly 1 5 0.2276166
GO:BP GO:0007411 axon guidance 2 177 0.2276166
GO:BP GO:0072014 proximal tubule development 1 8 0.2276166
GO:BP GO:0007164 establishment of tissue polarity 3 70 0.2276166
GO:BP GO:0045936 negative regulation of phosphate metabolic process 9 334 0.2276166
GO:BP GO:0038180 nerve growth factor signaling pathway 1 11 0.2276166
GO:BP GO:0071709 membrane assembly 4 54 0.2276166
GO:BP GO:1903083 protein localization to condensed chromosome 1 15 0.2295941
GO:BP GO:0034501 protein localization to kinetochore 1 15 0.2295941
GO:BP GO:0010563 negative regulation of phosphorus metabolic process 9 335 0.2298051
GO:BP GO:0032891 negative regulation of organic acid transport 1 18 0.2321933
GO:BP GO:0003071 renal system process involved in regulation of systemic arterial blood pressure 1 13 0.2321933
GO:BP GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation 1 13 0.2323644
GO:BP GO:0030071 regulation of mitotic metaphase/anaphase transition 5 87 0.2330791
GO:BP GO:0061009 common bile duct development 1 4 0.2331604
GO:BP GO:0072595 maintenance of protein localization in organelle 2 38 0.2345282
GO:BP GO:0042176 regulation of protein catabolic process 2 328 0.2348313
GO:BP GO:0070291 N-acylethanolamine metabolic process 1 4 0.2352673
GO:BP GO:0014741 negative regulation of muscle hypertrophy 1 26 0.2358539
GO:BP GO:0003007 heart morphogenesis 3 217 0.2358539
GO:BP GO:0042326 negative regulation of phosphorylation 8 290 0.2359653
GO:BP GO:0010826 negative regulation of centrosome duplication 1 12 0.2361606
GO:BP GO:0046606 negative regulation of centrosome cycle 1 12 0.2361606
GO:BP GO:0042551 neuron maturation 3 35 0.2361606
GO:BP GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 1 13 0.2367189
GO:BP GO:0043576 regulation of respiratory gaseous exchange 1 15 0.2377486
GO:BP GO:0016048 detection of temperature stimulus 1 12 0.2377486
GO:BP GO:0006661 phosphatidylinositol biosynthetic process 2 117 0.2378370
GO:BP GO:1901264 carbohydrate derivative transport 4 68 0.2378491
GO:BP GO:1904627 response to phorbol 13-acetate 12-myristate 1 4 0.2379327
GO:BP GO:1904628 cellular response to phorbol 13-acetate 12-myristate 1 4 0.2379327
GO:BP GO:0031573 mitotic intra-S DNA damage checkpoint signaling 2 15 0.2381852
GO:BP GO:0045893 positive regulation of DNA-templated transcription 24 1295 0.2381852
GO:BP GO:0071456 cellular response to hypoxia 2 121 0.2381852
GO:BP GO:0070901 mitochondrial tRNA methylation 1 4 0.2381852
GO:BP GO:0006046 N-acetylglucosamine catabolic process 1 3 0.2387477
GO:BP GO:0006041 glucosamine metabolic process 1 3 0.2387477
GO:BP GO:0042733 embryonic digit morphogenesis 1 50 0.2388525
GO:BP GO:0140650 radial glia-guided pyramidal neuron migration 1 4 0.2388525
GO:BP GO:0021540 corpus callosum morphogenesis 1 6 0.2388525
GO:BP GO:0007021 tubulin complex assembly 1 10 0.2388525
GO:BP GO:0045900 negative regulation of translational elongation 1 5 0.2388525
GO:BP GO:0051661 maintenance of centrosome location 1 6 0.2388525
GO:BP GO:1904415 regulation of xenophagy 1 7 0.2394246
GO:BP GO:1904417 positive regulation of xenophagy 1 7 0.2394246
GO:BP GO:0000394 RNA splicing, via endonucleolytic cleavage and ligation 1 14 0.2395727
GO:BP GO:0032462 regulation of protein homooligomerization 1 4 0.2395727
GO:BP GO:0006266 DNA ligation 2 16 0.2395727
GO:BP GO:1903860 negative regulation of dendrite extension 1 3 0.2395727
GO:BP GO:1900242 regulation of synaptic vesicle endocytosis 1 16 0.2395727
GO:BP GO:1901386 negative regulation of voltage-gated calcium channel activity 1 14 0.2395727
GO:BP GO:0006355 regulation of DNA-templated transcription 62 2562 0.2395727
GO:BP GO:0097193 intrinsic apoptotic signaling pathway 6 272 0.2395727
GO:BP GO:0014047 glutamate secretion 1 15 0.2400165
GO:BP GO:0010867 positive regulation of triglyceride biosynthetic process 1 13 0.2400165
GO:BP GO:0031109 microtubule polymerization or depolymerization 3 119 0.2418363
GO:BP GO:1902680 positive regulation of RNA biosynthetic process 24 1302 0.2419145
GO:BP GO:0006511 ubiquitin-dependent protein catabolic process 24 618 0.2431429
GO:BP GO:0120009 intermembrane lipid transfer 2 40 0.2431429
GO:BP GO:0016573 histone acetylation 6 110 0.2433373
GO:BP GO:0099517 synaptic vesicle transport along microtubule 1 15 0.2444042
GO:BP GO:0048490 anterograde synaptic vesicle transport 1 15 0.2444042
GO:BP GO:0099514 synaptic vesicle cytoskeletal transport 1 15 0.2444042
GO:BP GO:0010832 negative regulation of myotube differentiation 1 10 0.2450183
GO:BP GO:0050995 negative regulation of lipid catabolic process 1 14 0.2455053
GO:BP GO:0050996 positive regulation of lipid catabolic process 1 15 0.2455053
GO:BP GO:1905784 regulation of anaphase-promoting complex-dependent catabolic process 1 4 0.2455053
GO:BP GO:0062149 detection of stimulus involved in sensory perception of pain 1 14 0.2455053
GO:BP GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator 1 16 0.2455903
GO:BP GO:0045639 positive regulation of myeloid cell differentiation 1 66 0.2455903
GO:BP GO:1902099 regulation of metaphase/anaphase transition of cell cycle 5 88 0.2459410
GO:BP GO:0034497 protein localization to phagophore assembly site 1 16 0.2459410
GO:BP GO:1901020 negative regulation of calcium ion transmembrane transporter activity 3 28 0.2462417
GO:BP GO:0050994 regulation of lipid catabolic process 2 37 0.2462417
GO:BP GO:0033152 immunoglobulin V(D)J recombination 1 8 0.2462417
GO:BP GO:0001510 RNA methylation 5 89 0.2462417
GO:BP GO:0044790 suppression of viral release by host 2 16 0.2462417
GO:BP GO:0007004 telomere maintenance via telomerase 3 63 0.2462417
GO:BP GO:0002443 leukocyte mediated immunity 2 196 0.2462417
GO:BP GO:0006420 arginyl-tRNA aminoacylation 1 3 0.2462417
GO:BP GO:0043086 negative regulation of catalytic activity 11 456 0.2462417
GO:BP GO:0006418 tRNA aminoacylation for protein translation 3 40 0.2468670
GO:BP GO:0015886 heme transport 1 9 0.2471562
GO:BP GO:0090311 regulation of protein deacetylation 3 44 0.2477793
GO:BP GO:0060828 regulation of canonical Wnt signaling pathway 6 213 0.2477793
GO:BP GO:0010464 regulation of mesenchymal cell proliferation 1 26 0.2485753
GO:BP GO:0050951 sensory perception of temperature stimulus 1 12 0.2485753
GO:BP GO:0009127 purine nucleoside monophosphate biosynthetic process 2 20 0.2485753
GO:BP GO:0010046 response to mycotoxin 1 3 0.2485753
GO:BP GO:0062197 cellular response to chemical stress 1 268 0.2485753
GO:BP GO:0000076 DNA replication checkpoint signaling 2 16 0.2485753
GO:BP GO:0003094 glomerular filtration 1 20 0.2485753
GO:BP GO:0051953 negative regulation of amine transport 1 16 0.2485753
GO:BP GO:0007091 metaphase/anaphase transition of mitotic cell cycle 5 91 0.2489256
GO:BP GO:0051301 cell division 11 571 0.2489256
GO:BP GO:0097494 regulation of vesicle size 1 19 0.2489256
GO:BP GO:0010927 cellular component assembly involved in morphogenesis 2 106 0.2489256
GO:BP GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity 1 3 0.2489256
GO:BP GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2 43 0.2489256
GO:BP GO:0006278 RNA-templated DNA biosynthetic process 3 64 0.2495552
GO:BP GO:0014015 positive regulation of gliogenesis 1 44 0.2498287
GO:BP GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 1 15 0.2505307
GO:BP GO:0060122 inner ear receptor cell stereocilium organization 2 23 0.2505307
GO:BP GO:0042796 snRNA transcription by RNA polymerase III 1 8 0.2505307
GO:BP GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 1 16 0.2505307
GO:BP GO:0032456 endocytic recycling 5 79 0.2505307
GO:BP GO:0106058 positive regulation of calcineurin-mediated signaling 1 16 0.2505307
GO:BP GO:0034502 protein localization to chromosome 4 101 0.2518669
GO:BP GO:1990959 eosinophil homeostasis 1 2 0.2518797
GO:BP GO:0002343 peripheral B cell selection 1 2 0.2518797
GO:BP GO:0036294 cellular response to decreased oxygen levels 2 131 0.2518797
GO:BP GO:0018126 protein hydroxylation 1 25 0.2518797
GO:BP GO:0002344 B cell affinity maturation 1 2 0.2518797
GO:BP GO:2001141 regulation of RNA biosynthetic process 62 2579 0.2518797
GO:BP GO:0035308 negative regulation of protein dephosphorylation 1 27 0.2518797
GO:BP GO:0031023 microtubule organizing center organization 4 140 0.2518797
GO:BP GO:0042981 regulation of apoptotic process 12 1093 0.2518797
GO:BP GO:0030029 actin filament-based process 2 643 0.2520646
GO:BP GO:1902426 deactivation of mitotic spindle assembly checkpoint 1 2 0.2533673
GO:BP GO:0090233 negative regulation of spindle checkpoint 1 2 0.2533673
GO:BP GO:0048633 positive regulation of skeletal muscle tissue growth 1 6 0.2533673
GO:BP GO:0006895 Golgi to endosome transport 2 17 0.2533673
GO:BP GO:0140499 negative regulation of mitotic spindle assembly checkpoint signaling 1 2 0.2533673
GO:BP GO:0014732 skeletal muscle atrophy 1 5 0.2533673
GO:BP GO:0044091 membrane biogenesis 4 59 0.2533673
GO:BP GO:0038026 reelin-mediated signaling pathway 1 7 0.2549501
GO:BP GO:0000492 box C/D snoRNP assembly 1 10 0.2557438
GO:BP GO:0097205 renal filtration 1 22 0.2557438
GO:BP GO:0032785 negative regulation of DNA-templated transcription, elongation 2 21 0.2557438
GO:BP GO:0006506 GPI anchor biosynthetic process 1 30 0.2557438
GO:BP GO:0034138 toll-like receptor 3 signaling pathway 1 13 0.2557438
GO:BP GO:0036303 lymph vessel morphogenesis 1 17 0.2557438
GO:BP GO:0018364 peptidyl-glutamine methylation 1 4 0.2561636
GO:BP GO:0019941 modification-dependent protein catabolic process 24 628 0.2561982
GO:BP GO:0072344 rescue of stalled ribosome 2 22 0.2561982
GO:BP GO:0030307 positive regulation of cell growth 6 132 0.2564362
GO:BP GO:2000849 regulation of glucocorticoid secretion 1 5 0.2564362
GO:BP GO:0072521 purine-containing compound metabolic process 1 388 0.2564362
GO:BP GO:0021766 hippocampus development 3 70 0.2564362
GO:BP GO:0140245 regulation of translation at postsynapse 1 5 0.2570131
GO:BP GO:0033143 regulation of intracellular steroid hormone receptor signaling pathway 1 60 0.2570131
GO:BP GO:0140243 regulation of translation at synapse 1 5 0.2570131
GO:BP GO:0030488 tRNA methylation 3 43 0.2570131
GO:BP GO:0010522 regulation of calcium ion transport into cytosol 2 10 0.2570131
GO:BP GO:0009644 response to high light intensity 1 2 0.2570131
GO:BP GO:1904153 negative regulation of retrograde protein transport, ER to cytosol 1 9 0.2570131
GO:BP GO:0090150 establishment of protein localization to membrane 1 260 0.2570131
GO:BP GO:0010971 positive regulation of G2/M transition of mitotic cell cycle 2 28 0.2570131
GO:BP GO:1903321 negative regulation of protein modification by small protein conjugation or removal 3 86 0.2570131
GO:BP GO:0043456 regulation of pentose-phosphate shunt 1 6 0.2577911
GO:BP GO:0001921 positive regulation of receptor recycling 1 13 0.2582775
GO:BP GO:0006505 GPI anchor metabolic process 1 31 0.2582775
GO:BP GO:0048668 collateral sprouting 2 26 0.2582775
GO:BP GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1 5 0.2583416
GO:BP GO:0034248 regulation of amide metabolic process 10 427 0.2583416
GO:BP GO:0061024 membrane organization 3 663 0.2588465
GO:BP GO:0051443 positive regulation of ubiquitin-protein transferase activity 2 30 0.2588465
GO:BP GO:0016562 protein import into peroxisome matrix, receptor recycling 1 7 0.2588465
GO:BP GO:1904354 negative regulation of telomere capping 1 8 0.2588465
GO:BP GO:0032402 melanosome transport 2 19 0.2588465
GO:BP GO:0044784 metaphase/anaphase transition of cell cycle 5 92 0.2588465
GO:BP GO:0032623 interleukin-2 production 2 31 0.2588465
GO:BP GO:0006900 vesicle budding from membrane 4 77 0.2588465
GO:BP GO:1902806 regulation of cell cycle G1/S phase transition 7 164 0.2588465
GO:BP GO:0001911 negative regulation of leukocyte mediated cytotoxicity 1 11 0.2588465
GO:BP GO:0032663 regulation of interleukin-2 production 2 31 0.2588465
GO:BP GO:0098534 centriole assembly 2 41 0.2588465
GO:BP GO:0051444 negative regulation of ubiquitin-protein transferase activity 1 18 0.2588493
GO:BP GO:0006623 protein targeting to vacuole 3 43 0.2592622
GO:BP GO:0030261 chromosome condensation 2 34 0.2597736
GO:BP GO:0045685 regulation of glial cell differentiation 1 47 0.2606769
GO:BP GO:0098781 ncRNA transcription 6 118 0.2628303
GO:BP GO:0018026 peptidyl-lysine monomethylation 1 10 0.2628303
GO:BP GO:0048388 endosomal lumen acidification 1 13 0.2630234
GO:BP GO:1905232 cellular response to L-glutamate 1 4 0.2630234
GO:BP GO:0070262 peptidyl-serine dephosphorylation 1 14 0.2630234
GO:BP GO:0045165 cell fate commitment 2 157 0.2636962
GO:BP GO:0010923 negative regulation of phosphatase activity 1 29 0.2636962
GO:BP GO:0044090 positive regulation of vacuole organization 1 23 0.2636962
GO:BP GO:0018393 internal peptidyl-lysine acetylation 6 114 0.2636962
GO:BP GO:0006417 regulation of translation 9 374 0.2636962
GO:BP GO:0070676 intralumenal vesicle formation 1 4 0.2636962
GO:BP GO:0032930 positive regulation of superoxide anion generation 1 7 0.2636962
GO:BP GO:0016191 synaptic vesicle uncoating 1 6 0.2636962
GO:BP GO:0043039 tRNA aminoacylation 3 43 0.2636962
GO:BP GO:0048538 thymus development 1 35 0.2636962
GO:BP GO:1903542 negative regulation of exosomal secretion 1 4 0.2636962
GO:BP GO:0120186 negative regulation of protein localization to chromatin 1 5 0.2636962
GO:BP GO:0009153 purine deoxyribonucleotide biosynthetic process 1 4 0.2644199
GO:BP GO:0060292 long-term synaptic depression 1 22 0.2644199
GO:BP GO:0045777 positive regulation of blood pressure 1 15 0.2644199
GO:BP GO:0035590 purinergic nucleotide receptor signaling pathway 1 15 0.2644199
GO:BP GO:0046122 purine deoxyribonucleoside metabolic process 1 3 0.2644199
GO:BP GO:0016032 viral process 13 347 0.2661737
GO:BP GO:1903650 negative regulation of cytoplasmic transport 1 3 0.2661737
GO:BP GO:0006693 prostaglandin metabolic process 2 32 0.2662427
GO:BP GO:0090239 regulation of histone H4 acetylation 1 4 0.2668909
GO:BP GO:0002091 negative regulation of receptor internalization 1 14 0.2668909
GO:BP GO:0070862 negative regulation of protein exit from endoplasmic reticulum 1 10 0.2678235
GO:BP GO:0060056 mammary gland involution 1 8 0.2678235
GO:BP GO:0046469 platelet activating factor metabolic process 1 5 0.2678235
GO:BP GO:0046488 phosphatidylinositol metabolic process 2 135 0.2678235
GO:BP GO:0051098 regulation of binding 1 314 0.2678235
GO:BP GO:0006903 vesicle targeting 1 62 0.2678235
GO:BP GO:1902036 regulation of hematopoietic stem cell differentiation 1 15 0.2678235
GO:BP GO:0051904 pigment granule transport 2 19 0.2678235
GO:BP GO:0086004 regulation of cardiac muscle cell contraction 1 34 0.2678235
GO:BP GO:0032535 regulation of cellular component size 7 306 0.2678235
GO:BP GO:0032401 establishment of melanosome localization 2 20 0.2678235
GO:BP GO:0051254 positive regulation of RNA metabolic process 24 1422 0.2678235
GO:BP GO:0051649 establishment of localization in cell 2 1841 0.2678235
GO:BP GO:0010332 response to gamma radiation 2 47 0.2678235
GO:BP GO:0010824 regulation of centrosome duplication 2 44 0.2684078
GO:BP GO:0033674 positive regulation of kinase activity 3 307 0.2684078
GO:BP GO:0050790 regulation of catalytic activity 8 1348 0.2684078
GO:BP GO:0035878 nail development 1 8 0.2684078
GO:BP GO:0071560 cellular response to transforming growth factor beta stimulus 5 222 0.2684078
GO:BP GO:0051293 establishment of spindle localization 3 49 0.2684078
GO:BP GO:0043632 modification-dependent macromolecule catabolic process 24 638 0.2684078
GO:BP GO:0042439 ethanolamine-containing compound metabolic process 1 5 0.2684078
GO:BP GO:0043038 amino acid activation 3 44 0.2684078
GO:BP GO:0030111 regulation of Wnt signaling pathway 7 273 0.2684078
GO:BP GO:0006692 prostanoid metabolic process 2 33 0.2693658
GO:BP GO:0017157 regulation of exocytosis 1 139 0.2699896
GO:BP GO:0006475 internal protein amino acid acetylation 6 116 0.2702152
GO:BP GO:0036498 IRE1-mediated unfolded protein response 2 19 0.2711026
GO:BP GO:0043067 regulation of programmed cell death 12 1125 0.2711269
GO:BP GO:0051130 positive regulation of cellular component organization 1 906 0.2711269
GO:BP GO:0031056 regulation of histone modification 4 76 0.2711415
GO:BP GO:0006369 termination of RNA polymerase II transcription 1 9 0.2711415
GO:BP GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 2 41 0.2714996
GO:BP GO:0031929 TOR signaling 4 119 0.2716446
GO:BP GO:0048661 positive regulation of smooth muscle cell proliferation 1 60 0.2719058
GO:BP GO:0006259 DNA metabolic process 15 888 0.2719686
GO:BP GO:0071453 cellular response to oxygen levels 2 144 0.2719993
GO:BP GO:1900180 regulation of protein localization to nucleus 2 124 0.2721414
GO:BP GO:1903421 regulation of synaptic vesicle recycling 1 23 0.2721414
GO:BP GO:1901700 response to oxygen-containing compound 2 1220 0.2721414
GO:BP GO:0031342 negative regulation of cell killing 1 11 0.2721414
GO:BP GO:0001826 inner cell mass cell differentiation 1 5 0.2721414
GO:BP GO:1902570 protein localization to nucleolus 2 16 0.2722262
GO:BP GO:0035994 response to muscle stretch 1 25 0.2724518
GO:BP GO:0021510 spinal cord development 2 61 0.2729653
GO:BP GO:0030522 intracellular receptor signaling pathway 6 254 0.2729653
GO:BP GO:0034612 response to tumor necrosis factor 7 176 0.2730660
GO:BP GO:0032228 regulation of synaptic transmission, GABAergic 1 23 0.2732057
GO:BP GO:0000491 small nucleolar ribonucleoprotein complex assembly 1 12 0.2732057
GO:BP GO:0007492 endoderm development 1 65 0.2732057
GO:BP GO:0043392 negative regulation of DNA binding 2 44 0.2732057
GO:BP GO:0035092 sperm DNA condensation 1 7 0.2732057
GO:BP GO:1901678 iron coordination entity transport 1 11 0.2732057
GO:BP GO:0042753 positive regulation of circadian rhythm 1 9 0.2732057
GO:BP GO:0140861 DNA repair-dependent chromatin remodeling 1 18 0.2732057
GO:BP GO:0001845 phagolysosome assembly 2 14 0.2732057
GO:BP GO:0006979 response to oxidative stress 1 327 0.2733391
GO:BP GO:0061370 testosterone biosynthetic process 1 4 0.2737212
GO:BP GO:1901983 regulation of protein acetylation 2 49 0.2739196
GO:BP GO:0014888 striated muscle adaptation 3 39 0.2739196
GO:BP GO:0035933 glucocorticoid secretion 1 7 0.2741203
GO:BP GO:0021894 cerebral cortex GABAergic interneuron development 1 3 0.2741203
GO:BP GO:0051315 attachment of mitotic spindle microtubules to kinetochore 2 21 0.2746888
GO:BP GO:0051905 establishment of pigment granule localization 2 20 0.2746977
GO:BP GO:0030518 intracellular steroid hormone receptor signaling pathway 3 95 0.2746977
GO:BP GO:1902751 positive regulation of cell cycle G2/M phase transition 2 31 0.2746977
GO:BP GO:0005980 glycogen catabolic process 1 15 0.2746977
GO:BP GO:0071375 cellular response to peptide hormone stimulus 1 235 0.2746977
GO:BP GO:0039533 regulation of MDA-5 signaling pathway 1 5 0.2746977
GO:BP GO:0030336 negative regulation of cell migration 5 224 0.2751016
GO:BP GO:1904688 regulation of cytoplasmic translational initiation 1 7 0.2751016
GO:BP GO:0036066 protein O-linked fucosylation 1 5 0.2760008
GO:BP GO:0055086 nucleobase-containing small molecule metabolic process 1 486 0.2760008
GO:BP GO:1902905 positive regulation of supramolecular fiber organization 1 149 0.2760008
GO:BP GO:0071559 response to transforming growth factor beta 5 227 0.2763180
GO:BP GO:1901385 regulation of voltage-gated calcium channel activity 3 29 0.2763180
GO:BP GO:0032958 inositol phosphate biosynthetic process 1 20 0.2765200
GO:BP GO:0006950 response to stress 27 2767 0.2765200
GO:BP GO:0051851 modulation by host of symbiont process 1 71 0.2770106
GO:BP GO:0048597 post-embryonic camera-type eye morphogenesis 1 4 0.2770307
GO:BP GO:1900120 regulation of receptor binding 1 17 0.2772189
GO:BP GO:0022607 cellular component assembly 5 2472 0.2772189
GO:BP GO:0070346 positive regulation of fat cell proliferation 1 3 0.2772189
GO:BP GO:0046847 filopodium assembly 2 56 0.2772189
GO:BP GO:0045995 regulation of embryonic development 5 80 0.2779664
GO:BP GO:1902172 regulation of keratinocyte apoptotic process 1 5 0.2785388
GO:BP GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 1 18 0.2785388
GO:BP GO:0051988 regulation of attachment of spindle microtubules to kinetochore 1 18 0.2785388
GO:BP GO:0050890 cognition 7 225 0.2785388
GO:BP GO:0097283 keratinocyte apoptotic process 1 5 0.2785388
GO:BP GO:0070328 triglyceride homeostasis 1 18 0.2785388
GO:BP GO:0055090 acylglycerol homeostasis 1 18 0.2785388
GO:BP GO:0006893 Golgi to plasma membrane transport 3 58 0.2787301
GO:BP GO:0072318 clathrin coat disassembly 1 7 0.2787895
GO:BP GO:0051865 protein autoubiquitination 1 76 0.2787895
GO:BP GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic 1 18 0.2787895
GO:BP GO:0002710 negative regulation of T cell mediated immunity 1 9 0.2787895
GO:BP GO:0042149 cellular response to glucose starvation 3 46 0.2792215
GO:BP GO:0050714 positive regulation of protein secretion 2 103 0.2792215
GO:BP GO:0051047 positive regulation of secretion 3 209 0.2792215
GO:BP GO:0051171 regulation of nitrogen compound metabolic process 95 4247 0.2799521
GO:BP GO:0043549 regulation of kinase activity 4 548 0.2799521
GO:BP GO:2000172 regulation of branching morphogenesis of a nerve 1 4 0.2804119
GO:BP GO:0009251 glucan catabolic process 1 15 0.2804119
GO:BP GO:0016567 protein ubiquitination 6 683 0.2804119
GO:BP GO:0035970 peptidyl-threonine dephosphorylation 1 17 0.2804119
GO:BP GO:0120036 plasma membrane bounded cell projection organization 3 1202 0.2805102
GO:BP GO:0007018 microtubule-based movement 1 300 0.2806661
GO:BP GO:0051495 positive regulation of cytoskeleton organization 1 156 0.2813192
GO:BP GO:0010463 mesenchymal cell proliferation 1 36 0.2814394
GO:BP GO:0045472 response to ether 1 9 0.2815159
GO:BP GO:0006638 neutral lipid metabolic process 1 92 0.2816443
GO:BP GO:0014891 striated muscle atrophy 1 6 0.2816443
GO:BP GO:0048631 regulation of skeletal muscle tissue growth 1 7 0.2816443
GO:BP GO:0001843 neural tube closure 3 89 0.2816443
GO:BP GO:0006639 acylglycerol metabolic process 1 91 0.2816443
GO:BP GO:0050691 regulation of defense response to virus by host 3 31 0.2816443
GO:BP GO:1901165 positive regulation of trophoblast cell migration 1 6 0.2816443
GO:BP GO:0032928 regulation of superoxide anion generation 1 8 0.2816443
GO:BP GO:0008284 positive regulation of cell population proliferation 1 885 0.2816443
GO:BP GO:0032400 melanosome localization 2 22 0.2816443
GO:BP GO:0042921 glucocorticoid receptor signaling pathway 1 12 0.2816443
GO:BP GO:0071389 cellular response to mineralocorticoid stimulus 1 8 0.2816443
GO:BP GO:0030301 cholesterol transport 1 81 0.2828291
GO:BP GO:0032941 secretion by tissue 1 23 0.2829059
GO:BP GO:0042772 DNA damage response, signal transduction resulting in transcription 1 19 0.2829059
GO:BP GO:0046854 phosphatidylinositol phosphate biosynthetic process 3 57 0.2829059
GO:BP GO:0003016 respiratory system process 1 29 0.2829059
GO:BP GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 2 78 0.2829059
GO:BP GO:0042475 odontogenesis of dentin-containing tooth 1 55 0.2829059
GO:BP GO:0098792 xenophagy 1 12 0.2829059
GO:BP GO:1903115 regulation of actin filament-based movement 1 39 0.2829059
GO:BP GO:0010866 regulation of triglyceride biosynthetic process 1 19 0.2829059
GO:BP GO:0060606 tube closure 3 90 0.2831292
GO:BP GO:0032886 regulation of microtubule-based process 6 216 0.2831292
GO:BP GO:0140239 postsynaptic endocytosis 1 19 0.2831292
GO:BP GO:0098884 postsynaptic neurotransmitter receptor internalization 1 19 0.2831292
GO:BP GO:0006405 RNA export from nucleus 3 79 0.2831292
GO:BP GO:0043243 positive regulation of protein-containing complex disassembly 1 30 0.2836384
GO:BP GO:0046888 negative regulation of hormone secretion 2 49 0.2836384
GO:BP GO:0045017 glycerolipid biosynthetic process 8 215 0.2838769
GO:BP GO:0031062 positive regulation of histone methylation 2 23 0.2842737
GO:BP GO:1901097 negative regulation of autophagosome maturation 1 5 0.2844729
GO:BP GO:1990416 cellular response to brain-derived neurotrophic factor stimulus 1 8 0.2845844
GO:BP GO:0051090 regulation of DNA-binding transcription factor activity 1 332 0.2845844
GO:BP GO:0001942 hair follicle development 1 68 0.2845844
GO:BP GO:0000729 DNA double-strand break processing 2 19 0.2845844
GO:BP GO:0001945 lymph vessel development 1 22 0.2845844
GO:BP GO:0006892 post-Golgi vesicle-mediated transport 3 101 0.2845844
GO:BP GO:0022615 protein to membrane docking 1 5 0.2845844
GO:BP GO:1902415 regulation of mRNA binding 1 8 0.2845844
GO:BP GO:1904978 regulation of endosome organization 1 5 0.2845844
GO:BP GO:0010389 regulation of G2/M transition of mitotic cell cycle 5 94 0.2851465
GO:BP GO:0002328 pro-B cell differentiation 1 10 0.2858232
GO:BP GO:0099518 vesicle cytoskeletal trafficking 3 61 0.2859238
GO:BP GO:0061061 muscle structure development 6 551 0.2859238
GO:BP GO:0051642 centrosome localization 2 31 0.2860731
GO:BP GO:0030030 cell projection organization 3 1235 0.2860731
GO:BP GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 2 26 0.2860731
GO:BP GO:0061842 microtubule organizing center localization 2 31 0.2860731
GO:BP GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1 86 0.2860731
GO:BP GO:0032728 positive regulation of interferon-beta production 2 30 0.2861908
GO:BP GO:0061469 regulation of type B pancreatic cell proliferation 1 12 0.2861908
GO:BP GO:0090208 positive regulation of triglyceride metabolic process 1 16 0.2861908
GO:BP GO:0032811 negative regulation of epinephrine secretion 1 2 0.2861908
GO:BP GO:0009124 nucleoside monophosphate biosynthetic process 3 37 0.2861908
GO:BP GO:0042791 5S class rRNA transcription by RNA polymerase III 1 6 0.2861908
GO:BP GO:0072665 protein localization to vacuole 4 73 0.2861908
GO:BP GO:0035305 negative regulation of dephosphorylation 1 38 0.2861908
GO:BP GO:0032056 positive regulation of translation in response to stress 1 8 0.2861908
GO:BP GO:0032438 melanosome organization 2 36 0.2861908
GO:BP GO:0035624 receptor transactivation 1 3 0.2861908
GO:BP GO:0010700 negative regulation of norepinephrine secretion 1 2 0.2861908
GO:BP GO:1904903 ESCRT III complex disassembly 1 10 0.2861908
GO:BP GO:0051653 spindle localization 3 53 0.2861908
GO:BP GO:0022405 hair cycle process 1 70 0.2861908
GO:BP GO:0022404 molting cycle process 1 70 0.2861908
GO:BP GO:1904896 ESCRT complex disassembly 1 10 0.2861908
GO:BP GO:0048512 circadian behavior 1 30 0.2861908
GO:BP GO:0048488 synaptic vesicle endocytosis 4 62 0.2861908
GO:BP GO:0030163 protein catabolic process 3 906 0.2861908
GO:BP GO:0015937 coenzyme A biosynthetic process 1 11 0.2861908
GO:BP GO:0051875 pigment granule localization 2 22 0.2867467
GO:BP GO:0045445 myoblast differentiation 5 90 0.2867467
GO:BP GO:0051660 establishment of centrosome localization 1 8 0.2867467
GO:BP GO:0007613 memory 2 93 0.2867467
GO:BP GO:0032446 protein modification by small protein conjugation 28 758 0.2867467
GO:BP GO:1901874 negative regulation of post-translational protein modification 3 98 0.2867467
GO:BP GO:0031958 corticosteroid receptor signaling pathway 1 13 0.2867467
GO:BP GO:0051081 nuclear membrane disassembly 1 10 0.2867467
GO:BP GO:0033504 floor plate development 1 8 0.2879751
GO:BP GO:0009650 UV protection 1 11 0.2890719
GO:BP GO:0051955 regulation of amino acid transport 1 28 0.2890719
GO:BP GO:0000272 polysaccharide catabolic process 1 15 0.2890719
GO:BP GO:0071383 cellular response to steroid hormone stimulus 5 165 0.2890719
GO:BP GO:0090257 regulation of muscle system process 2 180 0.2890719
GO:BP GO:0010256 endomembrane system organization 15 497 0.2890719
GO:BP GO:0001738 morphogenesis of a polarized epithelium 3 88 0.2896343
GO:BP GO:0014013 regulation of gliogenesis 1 66 0.2896343
GO:BP GO:0010611 regulation of cardiac muscle hypertrophy 1 46 0.2896343
GO:BP GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation 2 25 0.2898082
GO:BP GO:2001258 negative regulation of cation channel activity 3 31 0.2898924
GO:BP GO:1901653 cellular response to peptide 1 278 0.2898924
GO:BP GO:0048753 pigment granule organization 2 37 0.2898924
GO:BP GO:0140238 presynaptic endocytosis 4 63 0.2898924
GO:BP GO:0019080 viral gene expression 1 97 0.2898924
GO:BP GO:0003266 regulation of secondary heart field cardioblast proliferation 1 8 0.2898924
GO:BP GO:0046474 glycerophospholipid biosynthetic process 7 186 0.2898924
GO:BP GO:0035307 positive regulation of protein dephosphorylation 1 35 0.2898924
GO:BP GO:0072319 vesicle uncoating 1 8 0.2898924
GO:BP GO:0071605 monocyte chemotactic protein-1 production 1 7 0.2898924
GO:BP GO:0051769 regulation of nitric-oxide synthase biosynthetic process 1 13 0.2898924
GO:BP GO:0046605 regulation of centrosome cycle 2 51 0.2898924
GO:BP GO:1900271 regulation of long-term synaptic potentiation 1 33 0.2898924
GO:BP GO:0007622 rhythmic behavior 1 32 0.2898924
GO:BP GO:0051767 nitric-oxide synthase biosynthetic process 1 13 0.2898924
GO:BP GO:1905279 regulation of retrograde transport, endosome to Golgi 1 6 0.2898924
GO:BP GO:0071637 regulation of monocyte chemotactic protein-1 production 1 7 0.2898924
GO:BP GO:0002260 lymphocyte homeostasis 4 49 0.2903365
GO:BP GO:1904152 regulation of retrograde protein transport, ER to cytosol 1 13 0.2903365
GO:BP GO:2001140 positive regulation of phospholipid transport 1 11 0.2903365
GO:BP GO:0032506 cytokinetic process 2 42 0.2903365
GO:BP GO:0043501 skeletal muscle adaptation 2 19 0.2903365
GO:BP GO:2000146 negative regulation of cell motility 5 233 0.2907018
GO:BP GO:0014902 myotube differentiation 2 88 0.2907018
GO:BP GO:0018022 peptidyl-lysine methylation 4 83 0.2910474
GO:BP GO:0071285 cellular response to lithium ion 1 8 0.2915284
GO:BP GO:0048709 oligodendrocyte differentiation 1 72 0.2915284
GO:BP GO:0015918 sterol transport 1 93 0.2925974
GO:BP GO:0034472 snRNA 3’-end processing 2 21 0.2930758
GO:BP GO:0016556 mRNA modification 2 32 0.2932382
GO:BP GO:0032459 regulation of protein oligomerization 1 7 0.2932382
GO:BP GO:0051494 negative regulation of cytoskeleton organization 3 136 0.2932382
GO:BP GO:0061098 positive regulation of protein tyrosine kinase activity 1 33 0.2932382
GO:BP GO:0051974 negative regulation of telomerase activity 1 11 0.2932382
GO:BP GO:0010288 response to lead ion 1 17 0.2932382
GO:BP GO:2000819 regulation of nucleotide-excision repair 2 27 0.2932382
GO:BP GO:2000481 positive regulation of cAMP-dependent protein kinase activity 1 5 0.2940755
GO:BP GO:0014020 primary neural tube formation 3 93 0.2944906
GO:BP GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 3 126 0.2949792
GO:BP GO:0035627 ceramide transport 1 14 0.2951927
GO:BP GO:0042311 vasodilation 1 37 0.2951927
GO:BP GO:0035025 positive regulation of Rho protein signal transduction 1 21 0.2951927
GO:BP GO:0045879 negative regulation of smoothened signaling pathway 1 30 0.2951927
GO:BP GO:0043268 positive regulation of potassium ion transport 1 31 0.2951927
GO:BP GO:0050657 nucleic acid transport 5 141 0.2951927
GO:BP GO:0009215 purine deoxyribonucleoside triphosphate metabolic process 1 7 0.2951927
GO:BP GO:0043651 linoleic acid metabolic process 1 12 0.2951927
GO:BP GO:0050658 RNA transport 5 141 0.2951927
GO:BP GO:0046053 dAMP metabolic process 1 5 0.2951927
GO:BP GO:0014743 regulation of muscle hypertrophy 1 47 0.2951927
GO:BP GO:0031063 regulation of histone deacetylation 2 26 0.2951927
GO:BP GO:1902031 regulation of NADP metabolic process 1 8 0.2956884
GO:BP GO:0006473 protein acetylation 6 154 0.2956884
GO:BP GO:0007338 single fertilization 1 69 0.2956884
GO:BP GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 1 98 0.2956884
GO:BP GO:1903320 regulation of protein modification by small protein conjugation or removal 6 231 0.2956884
GO:BP GO:0046486 glycerolipid metabolic process 3 302 0.2958264
GO:BP GO:1903322 positive regulation of protein modification by small protein conjugation or removal 4 125 0.2961257
GO:BP GO:0030397 membrane disassembly 1 11 0.2973018
GO:BP GO:0007179 transforming growth factor beta receptor signaling pathway 4 177 0.2973018
GO:BP GO:1902262 apoptotic process involved in blood vessel morphogenesis 1 4 0.2973018
GO:BP GO:1990090 cellular response to nerve growth factor stimulus 2 41 0.2973018
GO:BP GO:0043415 positive regulation of skeletal muscle tissue regeneration 1 3 0.2973018
GO:BP GO:2000275 regulation of oxidative phosphorylation uncoupler activity 1 5 0.2973018
GO:BP GO:0006650 glycerophospholipid metabolic process 9 243 0.2973018
GO:BP GO:0048701 embryonic cranial skeleton morphogenesis 2 31 0.2973760
GO:BP GO:0046328 regulation of JNK cascade 4 113 0.2974552
GO:BP GO:2001138 regulation of phospholipid transport 1 12 0.2992554
GO:BP GO:0046599 regulation of centriole replication 1 21 0.2992645
GO:BP GO:0044085 cellular component biogenesis 5 2735 0.2992645
GO:BP GO:0050688 regulation of defense response to virus 5 73 0.2995103
GO:BP GO:1903844 regulation of cellular response to transforming growth factor beta stimulus 3 127 0.3006970
GO:BP GO:0045591 positive regulation of regulatory T cell differentiation 1 14 0.3006970
GO:BP GO:0045776 negative regulation of blood pressure 1 30 0.3006970
GO:BP GO:0019219 regulation of nucleobase-containing compound metabolic process 70 3063 0.3006970
GO:BP GO:1903895 negative regulation of IRE1-mediated unfolded protein response 1 5 0.3006970
GO:BP GO:0006509 membrane protein ectodomain proteolysis 1 34 0.3006970
GO:BP GO:1990592 protein K69-linked ufmylation 1 5 0.3006970
GO:BP GO:1990564 protein polyufmylation 1 5 0.3006970
GO:BP GO:0034205 amyloid-beta formation 1 41 0.3006970
GO:BP GO:0003264 regulation of cardioblast proliferation 1 9 0.3021449
GO:BP GO:0003263 cardioblast proliferation 1 9 0.3021449
GO:BP GO:0070528 protein kinase C signaling 1 23 0.3024637
GO:BP GO:0051247 positive regulation of protein metabolic process 23 1065 0.3026804
GO:BP GO:2000846 regulation of corticosteroid hormone secretion 1 9 0.3027448
GO:BP GO:0032989 cellular component morphogenesis 6 626 0.3028912
GO:BP GO:0006508 proteolysis 4 1308 0.3028912
GO:BP GO:1902337 regulation of apoptotic process involved in morphogenesis 1 9 0.3028912
GO:BP GO:0051236 establishment of RNA localization 5 144 0.3028912
GO:BP GO:1904816 positive regulation of protein localization to chromosome, telomeric region 1 13 0.3028912
GO:BP GO:1901873 regulation of post-translational protein modification 12 301 0.3028912
GO:BP GO:0003281 ventricular septum development 1 69 0.3028912
GO:BP GO:0034654 nucleobase-containing compound biosynthetic process 67 3057 0.3028912
GO:BP GO:0002686 negative regulation of leukocyte migration 1 30 0.3028912
GO:BP GO:0048663 neuron fate commitment 1 28 0.3028912
GO:BP GO:1904748 regulation of apoptotic process involved in development 1 9 0.3028912
GO:BP GO:0071479 cellular response to ionizing radiation 2 64 0.3028912
GO:BP GO:0016192 vesicle-mediated transport 15 1230 0.3028912
GO:BP GO:0007519 skeletal muscle tissue development 2 128 0.3030809
GO:BP GO:2000060 positive regulation of ubiquitin-dependent protein catabolic process 1 99 0.3031371
GO:BP GO:0072488 ammonium transmembrane transport 1 6 0.3031682
GO:BP GO:2000629 negative regulation of miRNA metabolic process 2 23 0.3032203
GO:BP GO:0001841 neural tube formation 4 98 0.3037049
GO:BP GO:0008298 intracellular mRNA localization 1 10 0.3040588
GO:BP GO:0071897 DNA biosynthetic process 5 174 0.3044184
GO:BP GO:0002526 acute inflammatory response 2 50 0.3051635
GO:BP GO:0006703 estrogen biosynthetic process 1 6 0.3053598
GO:BP GO:0018130 heterocycle biosynthetic process 68 3118 0.3067471
GO:BP GO:0035067 negative regulation of histone acetylation 1 6 0.3067471
GO:BP GO:0032682 negative regulation of chemokine production 1 12 0.3067471
GO:BP GO:0016049 cell growth 13 415 0.3067471
GO:BP GO:2001137 positive regulation of endocytic recycling 1 7 0.3067471
GO:BP GO:0055118 negative regulation of cardiac muscle contraction 1 4 0.3069307
GO:BP GO:1990089 response to nerve growth factor 2 41 0.3071115
GO:BP GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 3 122 0.3071115
GO:BP GO:0065009 regulation of molecular function 40 1903 0.3071115
GO:BP GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1 15 0.3071681
GO:BP GO:0000956 nuclear-transcribed mRNA catabolic process 4 120 0.3079003
GO:BP GO:1904292 regulation of ERAD pathway 1 22 0.3079003
GO:BP GO:0031123 RNA 3’-end processing 2 92 0.3080555
GO:BP GO:0006189 ‘de novo’ IMP biosynthetic process 1 6 0.3082189
GO:BP GO:0070266 necroptotic process 1 34 0.3082189
GO:BP GO:1903170 negative regulation of calcium ion transmembrane transport 3 35 0.3082189
GO:BP GO:0043666 regulation of phosphoprotein phosphatase activity 1 46 0.3082189
GO:BP GO:0001961 positive regulation of cytokine-mediated signaling pathway 2 44 0.3087536
GO:BP GO:0090394 negative regulation of excitatory postsynaptic potential 1 9 0.3087536
GO:BP GO:0099590 neurotransmitter receptor internalization 1 21 0.3089658
GO:BP GO:0072657 protein localization to membrane 1 530 0.3089658
GO:BP GO:0010226 response to lithium ion 1 10 0.3089658
GO:BP GO:0042633 hair cycle 1 78 0.3089658
GO:BP GO:0042303 molting cycle 1 78 0.3089658
GO:BP GO:1903169 regulation of calcium ion transmembrane transport 2 120 0.3089658
GO:BP GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 1 165 0.3089658
GO:BP GO:0007517 muscle organ development 3 278 0.3089658
GO:BP GO:0043434 response to peptide hormone 1 316 0.3092705
GO:BP GO:1903430 negative regulation of cell maturation 1 4 0.3094562
GO:BP GO:2000171 negative regulation of dendrite development 1 6 0.3094562
GO:BP GO:1903441 protein localization to ciliary membrane 1 11 0.3099242
GO:BP GO:0051702 biological process involved in interaction with symbiont 1 81 0.3102067
GO:BP GO:0060612 adipose tissue development 2 45 0.3103894
GO:BP GO:0001783 B cell apoptotic process 2 21 0.3112174
GO:BP GO:0080134 regulation of response to stress 19 1073 0.3115461
GO:BP GO:0035113 embryonic appendage morphogenesis 1 89 0.3115461
GO:BP GO:0030326 embryonic limb morphogenesis 1 89 0.3115461
GO:BP GO:0060561 apoptotic process involved in morphogenesis 2 21 0.3115461
GO:BP GO:1901800 positive regulation of proteasomal protein catabolic process 1 107 0.3115461
GO:BP GO:0050772 positive regulation of axonogenesis 3 71 0.3119810
GO:BP GO:0019438 aromatic compound biosynthetic process 68 3119 0.3119810
GO:BP GO:0035556 intracellular signal transduction 18 2035 0.3119810
GO:BP GO:0009157 deoxyribonucleoside monophosphate biosynthetic process 1 8 0.3121875
GO:BP GO:0021761 limbic system development 1 89 0.3123269
GO:BP GO:2000625 regulation of miRNA catabolic process 1 5 0.3123269
GO:BP GO:0007254 JNK cascade 5 137 0.3123269
GO:BP GO:2000209 regulation of anoikis 1 23 0.3123269
GO:BP GO:2000197 regulation of ribonucleoprotein complex localization 1 6 0.3134905
GO:BP GO:0034198 cellular response to amino acid starvation 2 47 0.3134905
GO:BP GO:1903530 regulation of secretion by cell 4 381 0.3134905
GO:BP GO:0007409 axonogenesis 4 350 0.3157821
GO:BP GO:0032870 cellular response to hormone stimulus 2 449 0.3161479
GO:BP GO:1901463 regulation of tetrapyrrole biosynthetic process 1 7 0.3162898
GO:BP GO:0070453 regulation of heme biosynthetic process 1 7 0.3162898
GO:BP GO:0071702 organic substance transport 3 2134 0.3166521
GO:BP GO:1905634 regulation of protein localization to chromatin 1 9 0.3175312
GO:BP GO:0048630 skeletal muscle tissue growth 1 8 0.3175312
GO:BP GO:0014889 muscle atrophy 1 9 0.3175312
GO:BP GO:0044818 mitotic G2/M transition checkpoint 3 50 0.3184478
GO:BP GO:0048741 skeletal muscle fiber development 1 29 0.3184478
GO:BP GO:0050850 positive regulation of calcium-mediated signaling 1 22 0.3184478
GO:BP GO:0045721 negative regulation of gluconeogenesis 1 13 0.3184478
GO:BP GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation 1 5 0.3184478
GO:BP GO:0097116 gephyrin clustering involved in postsynaptic density assembly 1 3 0.3184478
GO:BP GO:1903051 negative regulation of proteolysis involved in protein catabolic process 2 62 0.3184478
GO:BP GO:0070884 regulation of calcineurin-NFAT signaling cascade 1 32 0.3184478
GO:BP GO:0022038 corpus callosum development 2 21 0.3186985
GO:BP GO:0000722 telomere maintenance via recombination 1 14 0.3190575
GO:BP GO:0051347 positive regulation of transferase activity 3 389 0.3204222
GO:BP GO:0051657 maintenance of organelle location 1 13 0.3204222
GO:BP GO:0001919 regulation of receptor recycling 1 22 0.3204222
GO:BP GO:1901362 organic cyclic compound biosynthetic process 70 3224 0.3204222
GO:BP GO:0016055 Wnt signaling pathway 9 378 0.3204222
GO:BP GO:0060538 skeletal muscle organ development 2 137 0.3204222
GO:BP GO:0034499 late endosome to Golgi transport 1 5 0.3204222
GO:BP GO:0031060 regulation of histone methylation 2 27 0.3204222
GO:BP GO:0006412 translation 14 657 0.3204507
GO:BP GO:0042797 tRNA transcription by RNA polymerase III 1 8 0.3205162
GO:BP GO:0051220 cytoplasmic sequestering of protein 2 25 0.3205162
GO:BP GO:0007286 spermatid development 1 108 0.3205162
GO:BP GO:0032507 maintenance of protein location in cell 2 57 0.3205162
GO:BP GO:0098773 skin epidermis development 1 90 0.3206943
GO:BP GO:0030865 cortical cytoskeleton organization 2 45 0.3211527
GO:BP GO:0106056 regulation of calcineurin-mediated signaling 1 32 0.3211527
GO:BP GO:0032469 endoplasmic reticulum calcium ion homeostasis 2 26 0.3211527
GO:BP GO:0050805 negative regulation of synaptic transmission 1 35 0.3211527
GO:BP GO:1901185 negative regulation of ERBB signaling pathway 2 30 0.3211527
GO:BP GO:0007289 spermatid nucleus differentiation 1 16 0.3211527
GO:BP GO:0043401 steroid hormone mediated signaling pathway 3 114 0.3216407
GO:BP GO:1905214 regulation of RNA binding 1 11 0.3216407
GO:BP GO:0198738 cell-cell signaling by wnt 9 379 0.3220416
GO:BP GO:0006825 copper ion transport 1 14 0.3223157
GO:BP GO:0060633 negative regulation of transcription initiation by RNA polymerase II 1 6 0.3223157
GO:BP GO:0035646 endosome to melanosome transport 1 9 0.3223157
GO:BP GO:0050435 amyloid-beta metabolic process 1 48 0.3223157
GO:BP GO:1902165 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 1 17 0.3223157
GO:BP GO:0048757 pigment granule maturation 1 9 0.3223157
GO:BP GO:0046785 microtubule polymerization 2 84 0.3223157
GO:BP GO:1904814 regulation of protein localization to chromosome, telomeric region 1 15 0.3223157
GO:BP GO:0043485 endosome to pigment granule transport 1 9 0.3223157
GO:BP GO:0042476 odontogenesis 1 82 0.3223157
GO:BP GO:0090322 regulation of superoxide metabolic process 1 16 0.3223157
GO:BP GO:0043029 T cell homeostasis 2 29 0.3223157
GO:BP GO:0061724 lipophagy 1 7 0.3227628
GO:BP GO:0060340 positive regulation of type I interferon-mediated signaling pathway 1 17 0.3227628
GO:BP GO:0045637 regulation of myeloid cell differentiation 1 138 0.3227628
GO:BP GO:0060485 mesenchyme development 1 250 0.3227628
GO:BP GO:0051668 localization within membrane 1 610 0.3227628
GO:BP GO:0043647 inositol phosphate metabolic process 1 36 0.3227628
GO:BP GO:0090383 phagosome acidification 1 5 0.3227628
GO:BP GO:0021892 cerebral cortex GABAergic interneuron differentiation 1 3 0.3227628
GO:BP GO:0042795 snRNA transcription by RNA polymerase II 1 15 0.3229488
GO:BP GO:0045935 positive regulation of nucleobase-containing compound metabolic process 26 1588 0.3230481
GO:BP GO:0090090 negative regulation of canonical Wnt signaling pathway 1 114 0.3230481
GO:BP GO:0071569 protein ufmylation 1 6 0.3232272
GO:BP GO:0035930 corticosteroid hormone secretion 1 12 0.3232272
GO:BP GO:0039530 MDA-5 signaling pathway 1 8 0.3232272
GO:BP GO:0045722 positive regulation of gluconeogenesis 1 18 0.3232272
GO:BP GO:0048515 spermatid differentiation 1 114 0.3232272
GO:BP GO:0000041 transition metal ion transport 3 74 0.3233024
GO:BP GO:0097345 mitochondrial outer membrane permeabilization 1 35 0.3236382
GO:BP GO:0012501 programmed cell death 14 1499 0.3236382
GO:BP GO:0007020 microtubule nucleation 1 39 0.3236382
GO:BP GO:0031953 negative regulation of protein autophosphorylation 1 8 0.3236382
GO:BP GO:0080090 regulation of primary metabolic process 100 4375 0.3236757
GO:BP GO:0051932 synaptic transmission, GABAergic 1 36 0.3236757
GO:BP GO:0009566 fertilization 1 93 0.3238737
GO:BP GO:0038173 interleukin-17A-mediated signaling pathway 1 5 0.3238737
GO:BP GO:0048660 regulation of smooth muscle cell proliferation 1 100 0.3243273
GO:BP GO:0033151 V(D)J recombination 1 15 0.3243639
GO:BP GO:0009896 positive regulation of catabolic process 10 465 0.3254154
GO:BP GO:0001959 regulation of cytokine-mediated signaling pathway 4 118 0.3254629
GO:BP GO:0032008 positive regulation of TOR signaling 2 47 0.3254984
GO:BP GO:0035306 positive regulation of dephosphorylation 1 46 0.3256407
GO:BP GO:0048489 synaptic vesicle transport 1 36 0.3256407
GO:BP GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 2 73 0.3256407
GO:BP GO:0008219 cell death 14 1505 0.3256407
GO:BP GO:1990928 response to amino acid starvation 2 50 0.3256407
GO:BP GO:0009200 deoxyribonucleoside triphosphate metabolic process 1 9 0.3256407
GO:BP GO:0042759 long-chain fatty acid biosynthetic process 1 13 0.3256407
GO:BP GO:0051972 regulation of telomerase activity 2 45 0.3256407
GO:BP GO:0044706 multi-multicellular organism process 1 136 0.3256407
GO:BP GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 4 143 0.3256407
GO:BP GO:0019752 carboxylic acid metabolic process 1 685 0.3256407
GO:BP GO:0048242 epinephrine secretion 1 2 0.3256407
GO:BP GO:0014060 regulation of epinephrine secretion 1 2 0.3256407
GO:BP GO:0097294 ‘de novo’ XMP biosynthetic process 1 7 0.3256407
GO:BP GO:0097293 XMP biosynthetic process 1 7 0.3256407
GO:BP GO:0019262 N-acetylneuraminate catabolic process 1 7 0.3256407
GO:BP GO:0060070 canonical Wnt signaling pathway 6 253 0.3256407
GO:BP GO:0097292 XMP metabolic process 1 7 0.3256407
GO:BP GO:1902749 regulation of cell cycle G2/M phase transition 5 105 0.3262936
GO:BP GO:0010506 regulation of autophagy 7 315 0.3269668
GO:BP GO:0048659 smooth muscle cell proliferation 1 104 0.3279020
GO:BP GO:0031623 receptor internalization 2 97 0.3279587
GO:BP GO:0030575 nuclear body organization 1 13 0.3288662
GO:BP GO:0006880 intracellular sequestering of iron ion 1 4 0.3292581
GO:BP GO:0065004 protein-DNA complex assembly 8 174 0.3298344
GO:BP GO:2000058 regulation of ubiquitin-dependent protein catabolic process 7 157 0.3298344
GO:BP GO:0051054 positive regulation of DNA metabolic process 9 267 0.3298433
GO:BP GO:0015866 ADP transport 1 10 0.3299077
GO:BP GO:0033173 calcineurin-NFAT signaling cascade 1 37 0.3299077
GO:BP GO:0006082 organic acid metabolic process 1 704 0.3299077
GO:BP GO:0010255 glucose mediated signaling pathway 1 5 0.3299077
GO:BP GO:0001514 selenocysteine incorporation 1 10 0.3299077
GO:BP GO:1903052 positive regulation of proteolysis involved in protein catabolic process 1 122 0.3299077
GO:BP GO:0090066 regulation of anatomical structure size 8 395 0.3299077
GO:BP GO:1901021 positive regulation of calcium ion transmembrane transporter activity 1 38 0.3299077
GO:BP GO:1901652 response to peptide 1 368 0.3299077
GO:BP GO:0007034 vacuolar transport 6 148 0.3299077
GO:BP GO:0010182 sugar mediated signaling pathway 1 5 0.3299077
GO:BP GO:0006451 translational readthrough 1 10 0.3299077
GO:BP GO:0051480 regulation of cytosolic calcium ion concentration 1 39 0.3299077
GO:BP GO:0031396 regulation of protein ubiquitination 5 193 0.3299077
GO:BP GO:0046471 phosphatidylglycerol metabolic process 2 23 0.3299077
GO:BP GO:0045198 establishment of epithelial cell apical/basal polarity 1 14 0.3299077
GO:BP GO:0043436 oxoacid metabolic process 1 700 0.3299077
GO:BP GO:0014904 myotube cell development 1 33 0.3299077
GO:BP GO:1901401 regulation of tetrapyrrole metabolic process 1 8 0.3299077
GO:BP GO:0009757 hexose mediated signaling 1 5 0.3299077
GO:BP GO:0042987 amyloid precursor protein catabolic process 1 53 0.3299077
GO:BP GO:0071233 cellular response to leucine 1 11 0.3306522
GO:BP GO:0010959 regulation of metal ion transport 3 271 0.3306620
GO:BP GO:0006779 porphyrin-containing compound biosynthetic process 2 32 0.3308100
GO:BP GO:0071166 ribonucleoprotein complex localization 1 7 0.3308100
GO:BP GO:0015800 acidic amino acid transport 1 39 0.3308100
GO:BP GO:1900244 positive regulation of synaptic vesicle endocytosis 1 4 0.3308100
GO:BP GO:0008015 blood circulation 1 372 0.3308100
GO:BP GO:0033014 tetrapyrrole biosynthetic process 2 32 0.3308100
GO:BP GO:0051497 negative regulation of stress fiber assembly 1 23 0.3308100
GO:BP GO:0001558 regulation of cell growth 11 351 0.3308256
GO:BP GO:0097300 programmed necrotic cell death 1 43 0.3309223
GO:BP GO:0098930 axonal transport 2 60 0.3311386
GO:BP GO:0060760 positive regulation of response to cytokine stimulus 2 48 0.3311386
GO:BP GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process 1 38 0.3311386
GO:BP GO:0010962 regulation of glucan biosynthetic process 1 26 0.3311386
GO:BP GO:0005979 regulation of glycogen biosynthetic process 1 26 0.3311386
GO:BP GO:0035722 interleukin-12-mediated signaling pathway 1 5 0.3311386
GO:BP GO:0043112 receptor metabolic process 3 67 0.3313048
GO:BP GO:0072594 establishment of protein localization to organelle 1 420 0.3313048
GO:BP GO:0016073 snRNA metabolic process 2 54 0.3316360
GO:BP GO:0031647 regulation of protein stability 2 293 0.3316360
GO:BP GO:0048261 negative regulation of receptor-mediated endocytosis 1 25 0.3317450
GO:BP GO:0033138 positive regulation of peptidyl-serine phosphorylation 3 68 0.3321698
GO:BP GO:0070050 neuron cellular homeostasis 1 45 0.3325405
GO:BP GO:0071459 protein localization to chromosome, centromeric region 1 29 0.3325405
GO:BP GO:0033120 positive regulation of RNA splicing 2 34 0.3332500
GO:BP GO:0071333 cellular response to glucose stimulus 2 95 0.3332500
GO:BP GO:0036465 synaptic vesicle recycling 4 72 0.3332500
GO:BP GO:0033619 membrane protein proteolysis 1 45 0.3332500
GO:BP GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 1 130 0.3332500
GO:BP GO:0051028 mRNA transport 4 115 0.3334019
GO:BP GO:0006887 exocytosis 1 251 0.3334019
GO:BP GO:0021819 layer formation in cerebral cortex 1 12 0.3335772
GO:BP GO:0040013 negative regulation of locomotion 5 262 0.3335772
GO:BP GO:0051056 regulation of small GTPase mediated signal transduction 1 249 0.3335772
GO:BP GO:0002791 regulation of peptide secretion 2 136 0.3335772
GO:BP GO:0035108 limb morphogenesis 1 113 0.3335772
GO:BP GO:0035107 appendage morphogenesis 1 113 0.3335772
GO:BP GO:1904936 interneuron migration 1 6 0.3335772
GO:BP GO:0050885 neuromuscular process controlling balance 2 35 0.3335772
GO:BP GO:0006622 protein targeting to lysosome 2 29 0.3335772
GO:BP GO:0051304 chromosome separation 4 75 0.3338001
GO:BP GO:0001914 regulation of T cell mediated cytotoxicity 1 23 0.3340303
GO:BP GO:0046602 regulation of mitotic centrosome separation 1 8 0.3341813
GO:BP GO:0043200 response to amino acid 5 94 0.3341981
GO:BP GO:0051154 negative regulation of striated muscle cell differentiation 1 30 0.3345667
GO:BP GO:0043065 positive regulation of apoptotic process 8 394 0.3345667
GO:BP GO:0043502 regulation of muscle adaptation 1 68 0.3350468
GO:BP GO:0016180 snRNA processing 2 26 0.3350677
GO:BP GO:0010032 meiotic chromosome condensation 1 6 0.3351326
GO:BP GO:0071331 cellular response to hexose stimulus 2 96 0.3357116
GO:BP GO:0090087 regulation of peptide transport 2 138 0.3357116
GO:BP GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening 1 33 0.3359912
GO:BP GO:0140894 endolysosomal toll-like receptor signaling pathway 1 25 0.3361904
GO:BP GO:0006109 regulation of carbohydrate metabolic process 3 147 0.3365252
GO:BP GO:0097720 calcineurin-mediated signaling 1 38 0.3365252
GO:BP GO:0002252 immune effector process 2 324 0.3365252
GO:BP GO:0098703 calcium ion import across plasma membrane 1 26 0.3365252
GO:BP GO:0051052 regulation of DNA metabolic process 10 458 0.3365252
GO:BP GO:0043085 positive regulation of catalytic activity 5 814 0.3365252
GO:BP GO:1902686 mitochondrial outer membrane permeabilization involved in programmed cell death 1 40 0.3365252
GO:BP GO:0006353 DNA-templated transcription termination 1 22 0.3365252
GO:BP GO:0040016 embryonic cleavage 1 7 0.3365252
GO:BP GO:0051648 vesicle localization 7 195 0.3373213
GO:BP GO:0051291 protein heterooligomerization 2 22 0.3373213
GO:BP GO:0055013 cardiac muscle cell development 1 74 0.3385820
GO:BP GO:0048534 hematopoietic or lymphoid organ development 1 71 0.3385820
GO:BP GO:0043547 positive regulation of GTPase activity 1 211 0.3385820
GO:BP GO:1901135 carbohydrate derivative metabolic process 1 843 0.3385820
GO:BP GO:0000423 mitophagy 1 37 0.3385820
GO:BP GO:0071326 cellular response to monosaccharide stimulus 2 97 0.3385820
GO:BP GO:0006448 regulation of translational elongation 1 12 0.3385820
GO:BP GO:2000143 negative regulation of DNA-templated transcription initiation 1 6 0.3385820
GO:BP GO:0051125 regulation of actin nucleation 1 31 0.3385820
GO:BP GO:0050821 protein stabilization 4 196 0.3385820
GO:BP GO:0000712 resolution of meiotic recombination intermediates 1 13 0.3390227
GO:BP GO:1990542 mitochondrial transmembrane transport 1 57 0.3390227
GO:BP GO:0060402 calcium ion transport into cytosol 2 18 0.3391469
GO:BP GO:0008053 mitochondrial fusion 2 29 0.3391469
GO:BP GO:2000831 regulation of steroid hormone secretion 1 13 0.3391469
GO:BP GO:0006833 water transport 1 12 0.3393243
GO:BP GO:0003300 cardiac muscle hypertrophy 1 72 0.3396767
GO:BP GO:0001947 heart looping 3 50 0.3396767
GO:BP GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 2 51 0.3396767
GO:BP GO:0042255 ribosome assembly 2 62 0.3396767
GO:BP GO:1901992 positive regulation of mitotic cell cycle phase transition 4 84 0.3402994
GO:BP GO:0071407 cellular response to organic cyclic compound 10 407 0.3402994
GO:BP GO:0015936 coenzyme A metabolic process 1 18 0.3423954
GO:BP GO:0044242 cellular lipid catabolic process 1 168 0.3423954
GO:BP GO:1903367 positive regulation of fear response 1 4 0.3423954
GO:BP GO:0071396 cellular response to lipid 11 400 0.3423954
GO:BP GO:2000765 regulation of cytoplasmic translation 2 30 0.3423954
GO:BP GO:0044208 ‘de novo’ AMP biosynthetic process 1 8 0.3423954
GO:BP GO:0043482 cellular pigment accumulation 1 11 0.3423954
GO:BP GO:0048167 regulation of synaptic plasticity 2 146 0.3423954
GO:BP GO:0042249 establishment of planar polarity of embryonic epithelium 1 15 0.3423954
GO:BP GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process 1 42 0.3423954
GO:BP GO:0009301 snRNA transcription 1 18 0.3423954
GO:BP GO:0032092 positive regulation of protein binding 2 78 0.3423954
GO:BP GO:0032232 negative regulation of actin filament bundle assembly 1 26 0.3423954
GO:BP GO:0043476 pigment accumulation 1 11 0.3423954
GO:BP GO:0015074 DNA integration 1 9 0.3423954
GO:BP GO:0001188 RNA polymerase I preinitiation complex assembly 1 8 0.3423954
GO:BP GO:1990253 cellular response to leucine starvation 1 13 0.3423954
GO:BP GO:0051046 regulation of secretion 4 412 0.3423954
GO:BP GO:0051491 positive regulation of filopodium assembly 1 25 0.3423954
GO:BP GO:0035794 positive regulation of mitochondrial membrane permeability 1 42 0.3423954
GO:BP GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport 1 118 0.3424347
GO:BP GO:0031669 cellular response to nutrient levels 8 198 0.3426151
GO:BP GO:2001242 regulation of intrinsic apoptotic signaling pathway 3 157 0.3432411
GO:BP GO:0051650 establishment of vesicle localization 2 178 0.3432411
GO:BP GO:0007163 establishment or maintenance of cell polarity 5 198 0.3438369
GO:BP GO:0051168 nuclear export 6 149 0.3443557
GO:BP GO:0006307 DNA dealkylation involved in DNA repair 1 9 0.3445346
GO:BP GO:0043043 peptide biosynthetic process 14 677 0.3445346
GO:BP GO:0009247 glycolipid biosynthetic process 1 62 0.3449083
GO:BP GO:0014897 striated muscle hypertrophy 1 73 0.3450410
GO:BP GO:1900101 regulation of endoplasmic reticulum unfolded protein response 2 29 0.3453014
GO:BP GO:0038179 neurotrophin signaling pathway 1 36 0.3453014
GO:BP GO:0032210 regulation of telomere maintenance via telomerase 2 49 0.3453364
GO:BP GO:0034389 lipid droplet organization 1 30 0.3458681
GO:BP GO:0045589 regulation of regulatory T cell differentiation 1 21 0.3458681
GO:BP GO:0070316 regulation of G0 to G1 transition 2 33 0.3460977
GO:BP GO:0097577 sequestering of iron ion 1 5 0.3469452
GO:BP GO:0008333 endosome to lysosome transport 3 63 0.3469452
GO:BP GO:0033235 positive regulation of protein sumoylation 1 12 0.3469452
GO:BP GO:0032608 interferon-beta production 3 45 0.3469452
GO:BP GO:0032648 regulation of interferon-beta production 3 45 0.3469452
GO:BP GO:0009855 determination of bilateral symmetry 5 101 0.3469452
GO:BP GO:0009799 specification of symmetry 5 101 0.3469452
GO:BP GO:0007094 mitotic spindle assembly checkpoint signaling 1 43 0.3473314
GO:BP GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 3 44 0.3473314
GO:BP GO:0071173 spindle assembly checkpoint signaling 1 43 0.3473314
GO:BP GO:0071174 mitotic spindle checkpoint signaling 1 43 0.3473314
GO:BP GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 2 63 0.3473314
GO:BP GO:0060759 regulation of response to cytokine stimulus 4 126 0.3476961
GO:BP GO:0055006 cardiac cell development 1 80 0.3481372
GO:BP GO:0043543 protein acylation 8 192 0.3481372
GO:BP GO:0014896 muscle hypertrophy 1 74 0.3481372
GO:BP GO:1904779 regulation of protein localization to centrosome 1 10 0.3481372
GO:BP GO:0003279 cardiac septum development 1 101 0.3484034
GO:BP GO:0042127 regulation of cell population proliferation 1 1567 0.3493100
GO:BP GO:0009170 purine deoxyribonucleoside monophosphate metabolic process 1 8 0.3495625
GO:BP GO:0033209 tumor necrosis factor-mediated signaling pathway 3 80 0.3495625
GO:BP GO:0044271 cellular nitrogen compound biosynthetic process 78 3747 0.3495625
GO:BP GO:0030178 negative regulation of Wnt signaling pathway 1 140 0.3495625
GO:BP GO:0036035 osteoclast development 1 10 0.3495625
GO:BP GO:0060218 hematopoietic stem cell differentiation 1 30 0.3495625
GO:BP GO:0098751 bone cell development 1 10 0.3495625
GO:BP GO:0009120 deoxyribonucleoside metabolic process 1 9 0.3495625
GO:BP GO:0071384 cellular response to corticosteroid stimulus 2 44 0.3495625
GO:BP GO:0043255 regulation of carbohydrate biosynthetic process 2 79 0.3495625
GO:BP GO:0032261 purine nucleotide salvage 1 10 0.3495625
GO:BP GO:0086003 cardiac muscle cell contraction 1 67 0.3495625
GO:BP GO:0061003 positive regulation of dendritic spine morphogenesis 1 16 0.3495625
GO:BP GO:0007175 negative regulation of epidermal growth factor-activated receptor activity 1 13 0.3495625
GO:BP GO:0031577 spindle checkpoint signaling 1 44 0.3499907
GO:BP GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1 22 0.3501241
GO:BP GO:0003013 circulatory system process 1 445 0.3504780
GO:BP GO:1905710 positive regulation of membrane permeability 1 43 0.3506003
GO:BP GO:0032897 negative regulation of viral transcription 1 15 0.3510490
GO:BP GO:0043276 anoikis 1 32 0.3517310
GO:BP GO:0009267 cellular response to starvation 6 148 0.3519624
GO:BP GO:2000008 regulation of protein localization to cell surface 1 37 0.3522324
GO:BP GO:0071397 cellular response to cholesterol 1 12 0.3524055
GO:BP GO:0044088 regulation of vacuole organization 1 51 0.3532880
GO:BP GO:0014874 response to stimulus involved in regulation of muscle adaptation 1 13 0.3537509
GO:BP GO:0045841 negative regulation of mitotic metaphase/anaphase transition 1 45 0.3537509
GO:BP GO:2000816 negative regulation of mitotic sister chromatid separation 1 45 0.3537509
GO:BP GO:0033046 negative regulation of sister chromatid segregation 1 45 0.3537509
GO:BP GO:0060537 muscle tissue development 3 346 0.3537509
GO:BP GO:0033048 negative regulation of mitotic sister chromatid segregation 1 45 0.3537509
GO:BP GO:0072583 clathrin-dependent endocytosis 1 43 0.3537509
GO:BP GO:0032727 positive regulation of interferon-alpha production 1 17 0.3537779
GO:BP GO:0016310 phosphorylation 27 1339 0.3537779
GO:BP GO:0051604 protein maturation 3 442 0.3539107
GO:BP GO:0051298 centrosome duplication 2 68 0.3539107
GO:BP GO:1903896 positive regulation of IRE1-mediated unfolded protein response 1 7 0.3545638
GO:BP GO:0050795 regulation of behavior 1 41 0.3545638
GO:BP GO:0055117 regulation of cardiac muscle contraction 1 69 0.3545638
GO:BP GO:0048050 post-embryonic eye morphogenesis 1 7 0.3545638
GO:BP GO:0051172 negative regulation of nitrogen compound metabolic process 36 1832 0.3545638
GO:BP GO:0045834 positive regulation of lipid metabolic process 2 108 0.3545638
GO:BP GO:0043416 regulation of skeletal muscle tissue regeneration 1 4 0.3545638
GO:BP GO:0002707 negative regulation of lymphocyte mediated immunity 1 24 0.3545638
GO:BP GO:0034968 histone lysine methylation 3 65 0.3545638
GO:BP GO:0031077 post-embryonic camera-type eye development 1 7 0.3545638
GO:BP GO:0010906 regulation of glucose metabolic process 2 85 0.3545638
GO:BP GO:0001913 T cell mediated cytotoxicity 1 29 0.3545638
GO:BP GO:0007585 respiratory gaseous exchange by respiratory system 1 48 0.3545638
GO:BP GO:0043470 regulation of carbohydrate catabolic process 2 51 0.3546205
GO:BP GO:0045947 negative regulation of translational initiation 1 18 0.3552182
GO:BP GO:2001267 regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1 13 0.3552182
GO:BP GO:0071322 cellular response to carbohydrate stimulus 2 106 0.3552182
GO:BP GO:0070873 regulation of glycogen metabolic process 1 29 0.3552182
GO:BP GO:0010921 regulation of phosphatase activity 1 64 0.3553960
GO:BP GO:0043068 positive regulation of programmed cell death 8 403 0.3560146
GO:BP GO:0008089 anterograde axonal transport 1 46 0.3560226
GO:BP GO:0061564 axon development 4 388 0.3564233
GO:BP GO:1901072 glucosamine-containing compound catabolic process 1 5 0.3564233
GO:BP GO:0006048 UDP-N-acetylglucosamine biosynthetic process 1 9 0.3564233
GO:BP GO:0071392 cellular response to estradiol stimulus 1 25 0.3564233
GO:BP GO:0071349 cellular response to interleukin-12 1 7 0.3564233
GO:BP GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 1 10 0.3566363
GO:BP GO:0009756 carbohydrate mediated signaling 1 6 0.3566363
GO:BP GO:0061097 regulation of protein tyrosine kinase activity 1 61 0.3579421
GO:BP GO:0072359 circulatory system development 6 888 0.3579421
GO:BP GO:0045023 G0 to G1 transition 2 34 0.3579421
GO:BP GO:0010830 regulation of myotube differentiation 1 31 0.3579421
GO:BP GO:0051985 negative regulation of chromosome segregation 1 46 0.3579421
GO:BP GO:0045892 negative regulation of DNA-templated transcription 9 1004 0.3579421
GO:BP GO:0048671 negative regulation of collateral sprouting 1 10 0.3579421
GO:BP GO:0031401 positive regulation of protein modification process 15 662 0.3579421
GO:BP GO:0017183 protein histidyl modification to diphthamide 1 7 0.3579421
GO:BP GO:0032890 regulation of organic acid transport 1 48 0.3579421
GO:BP GO:1902100 negative regulation of metaphase/anaphase transition of cell cycle 1 46 0.3579421
GO:BP GO:2000095 regulation of Wnt signaling pathway, planar cell polarity pathway 1 15 0.3579421
GO:BP GO:0048755 branching morphogenesis of a nerve 1 9 0.3579421
GO:BP GO:1905819 negative regulation of chromosome separation 1 46 0.3579421
GO:BP GO:0030308 negative regulation of cell growth 5 161 0.3579421
GO:BP GO:1900182 positive regulation of protein localization to nucleus 2 81 0.3579421
GO:BP GO:0038202 TORC1 signaling 2 60 0.3579421
GO:BP GO:0002447 eosinophil mediated immunity 1 5 0.3579421
GO:BP GO:0045927 positive regulation of growth 7 196 0.3579421
GO:BP GO:0071222 cellular response to lipopolysaccharide 3 114 0.3579421
GO:BP GO:0032885 regulation of polysaccharide biosynthetic process 1 32 0.3579421
GO:BP GO:0042274 ribosomal small subunit biogenesis 4 102 0.3582534
GO:BP GO:2000480 negative regulation of cAMP-dependent protein kinase activity 1 8 0.3582534
GO:BP GO:0043652 engulfment of apoptotic cell 1 8 0.3582534
GO:BP GO:0045066 regulatory T cell differentiation 1 22 0.3582534
GO:BP GO:0019432 triglyceride biosynthetic process 1 32 0.3582534
GO:BP GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1 26 0.3582534
GO:BP GO:0051173 positive regulation of nitrogen compound metabolic process 45 2366 0.3582534
GO:BP GO:0070887 cellular response to chemical stimulus 2 1856 0.3582534
GO:BP GO:0051126 negative regulation of actin nucleation 1 6 0.3582534
GO:BP GO:0043045 post-fertilization epigenetic regulation of gene expression 1 7 0.3582534
GO:BP GO:0055064 chloride ion homeostasis 1 12 0.3582534
GO:BP GO:0044342 type B pancreatic cell proliferation 1 24 0.3582944
GO:BP GO:0046173 polyol biosynthetic process 1 47 0.3586047
GO:BP GO:0043270 positive regulation of monoatomic ion transport 2 151 0.3586047
GO:BP GO:0003002 regionalization 1 271 0.3596171
GO:BP GO:2000001 regulation of DNA damage checkpoint 1 24 0.3598439
GO:BP GO:0071417 cellular response to organonitrogen compound 1 472 0.3598439
GO:BP GO:0032211 negative regulation of telomere maintenance via telomerase 1 19 0.3598439
GO:BP GO:0051966 regulation of synaptic transmission, glutamatergic 1 46 0.3598439
GO:BP GO:0043304 regulation of mast cell degranulation 1 19 0.3598439
GO:BP GO:0051179 localization 4 3982 0.3598439
GO:BP GO:0030334 regulation of cell migration 4 706 0.3598439
GO:BP GO:0033365 protein localization to organelle 16 862 0.3598439
GO:BP GO:0001782 B cell homeostasis 2 24 0.3598439
GO:BP GO:0019058 viral life cycle 9 245 0.3598439
GO:BP GO:0009057 macromolecule catabolic process 22 1213 0.3598439
GO:BP GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 1 37 0.3598439
GO:BP GO:0006915 apoptotic process 13 1453 0.3600541
GO:BP GO:1903649 regulation of cytoplasmic transport 2 27 0.3601401
GO:BP GO:0033313 meiotic cell cycle checkpoint signaling 1 6 0.3601401
GO:BP GO:0035089 establishment of apical/basal cell polarity 1 18 0.3601401
GO:BP GO:0001678 intracellular glucose homeostasis 2 112 0.3604845
GO:BP GO:0044458 motile cilium assembly 2 46 0.3604845
GO:BP GO:0016241 regulation of macroautophagy 3 149 0.3604845
GO:BP GO:0031331 positive regulation of cellular catabolic process 5 282 0.3613926
GO:BP GO:1901532 regulation of hematopoietic progenitor cell differentiation 1 34 0.3613926
GO:BP GO:0019233 sensory perception of pain 1 39 0.3613926
GO:BP GO:0007026 negative regulation of microtubule depolymerization 1 25 0.3617152
GO:BP GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 2 78 0.3617152
GO:BP GO:1905820 positive regulation of chromosome separation 2 28 0.3617152
GO:BP GO:0045988 negative regulation of striated muscle contraction 1 7 0.3622664
GO:BP GO:0042982 amyloid precursor protein metabolic process 1 70 0.3633667
GO:BP GO:0090382 phagosome maturation 2 24 0.3641662
GO:BP GO:0015914 phospholipid transport 2 72 0.3641878
GO:BP GO:1902679 negative regulation of RNA biosynthetic process 9 1013 0.3641878
GO:BP GO:0008654 phospholipid biosynthetic process 2 231 0.3641878
GO:BP GO:0034314 Arp2/3 complex-mediated actin nucleation 1 40 0.3652892
GO:BP GO:0045089 positive regulation of innate immune response 4 206 0.3653664
GO:BP GO:0061371 determination of heart left/right asymmetry 3 52 0.3653727
GO:BP GO:0097479 synaptic vesicle localization 1 50 0.3653727
GO:BP GO:0003143 embryonic heart tube morphogenesis 3 56 0.3653727
GO:BP GO:1905150 regulation of voltage-gated sodium channel activity 1 6 0.3657866
GO:BP GO:0035929 steroid hormone secretion 1 18 0.3657866
GO:BP GO:0048738 cardiac muscle tissue development 2 202 0.3657866
GO:BP GO:0090207 regulation of triglyceride metabolic process 1 28 0.3658480
GO:BP GO:2001244 positive regulation of intrinsic apoptotic signaling pathway 2 52 0.3658480
GO:BP GO:2000671 regulation of motor neuron apoptotic process 1 12 0.3658496
GO:BP GO:1990403 embryonic brain development 1 13 0.3658496
GO:BP GO:0002320 lymphoid progenitor cell differentiation 1 17 0.3661014
GO:BP GO:0001838 embryonic epithelial tube formation 3 113 0.3661014
GO:BP GO:2000766 negative regulation of cytoplasmic translation 1 9 0.3662933
GO:BP GO:0006664 glycolipid metabolic process 2 89 0.3662933
GO:BP GO:1903423 positive regulation of synaptic vesicle recycling 1 6 0.3668418
GO:BP GO:0021543 pallium development 1 146 0.3668418
GO:BP GO:0060444 branching involved in mammary gland duct morphogenesis 1 20 0.3671931
GO:BP GO:0070671 response to interleukin-12 1 8 0.3676209
GO:BP GO:0002230 positive regulation of defense response to virus by host 2 23 0.3679075
GO:BP GO:0006390 mitochondrial transcription 1 19 0.3679075
GO:BP GO:1901565 organonitrogen compound catabolic process 3 1151 0.3679075
GO:BP GO:2000757 negative regulation of peptidyl-lysine acetylation 1 10 0.3682280
GO:BP GO:0044093 positive regulation of molecular function 6 1130 0.3682280
GO:BP GO:0009755 hormone-mediated signaling pathway 1 141 0.3682280
GO:BP GO:1902523 positive regulation of protein K63-linked ubiquitination 1 6 0.3682280
GO:BP GO:0044539 long-chain fatty acid import into cell 1 14 0.3682280
GO:BP GO:1901699 cellular response to nitrogen compound 1 502 0.3682280
GO:BP GO:0008088 axo-dendritic transport 2 72 0.3682280
GO:BP GO:0048585 negative regulation of response to stimulus 21 1266 0.3682280
GO:BP GO:0046579 positive regulation of Ras protein signal transduction 1 42 0.3682280
GO:BP GO:1903509 liposaccharide metabolic process 2 89 0.3682865
GO:BP GO:0006361 transcription initiation at RNA polymerase I promoter 1 10 0.3683391
GO:BP GO:0051290 protein heterotetramerization 1 12 0.3686131
GO:BP GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration 1 9 0.3690874
GO:BP GO:0015867 ATP transport 1 12 0.3693516
GO:BP GO:0046626 regulation of insulin receptor signaling pathway 2 53 0.3695818
GO:BP GO:0033006 regulation of mast cell activation involved in immune response 1 20 0.3695818
GO:BP GO:1901163 regulation of trophoblast cell migration 1 12 0.3695818
GO:BP GO:0002820 negative regulation of adaptive immune response 1 27 0.3699652
GO:BP GO:0046902 regulation of mitochondrial membrane permeability 1 53 0.3701195
GO:BP GO:0009113 purine nucleobase biosynthetic process 1 10 0.3703671
GO:BP GO:0003231 cardiac ventricle development 1 115 0.3703671
GO:BP GO:0070861 regulation of protein exit from endoplasmic reticulum 1 22 0.3707486
GO:BP GO:0042554 superoxide anion generation 1 18 0.3712003
GO:BP GO:0071219 cellular response to molecule of bacterial origin 3 118 0.3719328
GO:BP GO:0042325 regulation of phosphorylation 18 841 0.3719973
GO:BP GO:0055008 cardiac muscle tissue morphogenesis 1 55 0.3720034
GO:BP GO:0006111 regulation of gluconeogenesis 2 42 0.3721042
GO:BP GO:0043500 muscle adaptation 1 89 0.3728329
GO:BP GO:0051261 protein depolymerization 3 100 0.3735109
GO:BP GO:0055081 monoatomic anion homeostasis 1 13 0.3736032
GO:BP GO:1905821 positive regulation of chromosome condensation 1 8 0.3736189
GO:BP GO:0019220 regulation of phosphate metabolic process 5 949 0.3740198
GO:BP GO:1904427 positive regulation of calcium ion transmembrane transport 4 59 0.3744248
GO:BP GO:0045839 negative regulation of mitotic nuclear division 1 53 0.3744248
GO:BP GO:0051174 regulation of phosphorus metabolic process 5 950 0.3744248
GO:BP GO:0007099 centriole replication 1 38 0.3744248
GO:BP GO:0061162 establishment of monopolar cell polarity 1 20 0.3744248
GO:BP GO:1902116 negative regulation of organelle assembly 1 38 0.3744248
GO:BP GO:0007389 pattern specification process 1 304 0.3747013
GO:BP GO:0000209 protein polyubiquitination 9 238 0.3747013
GO:BP GO:0033002 muscle cell proliferation 1 153 0.3747139
GO:BP GO:2000136 regulation of cell proliferation involved in heart morphogenesis 1 17 0.3747326
GO:BP GO:0021953 central nervous system neuron differentiation 4 112 0.3748678
GO:BP GO:0043066 negative regulation of apoptotic process 4 662 0.3753137
GO:BP GO:0006406 mRNA export from nucleus 3 60 0.3761417
GO:BP GO:0042044 fluid transport 1 19 0.3762561
GO:BP GO:1903651 positive regulation of cytoplasmic transport 1 13 0.3766860
GO:BP GO:0045185 maintenance of protein location 4 84 0.3766860
GO:BP GO:0032369 negative regulation of lipid transport 1 20 0.3772633
GO:BP GO:0007589 body fluid secretion 1 58 0.3774406
GO:BP GO:0016042 lipid catabolic process 4 224 0.3777019
GO:BP GO:0010972 negative regulation of G2/M transition of mitotic cell cycle 3 60 0.3778314
GO:BP GO:0098974 postsynaptic actin cytoskeleton organization 1 14 0.3778314
GO:BP GO:0043087 regulation of GTPase activity 1 288 0.3778314
GO:BP GO:1901977 negative regulation of cell cycle checkpoint 1 7 0.3781409
GO:BP GO:2000234 positive regulation of rRNA processing 1 10 0.3781409
GO:BP GO:0017156 calcium-ion regulated exocytosis 1 46 0.3782075
GO:BP GO:0051926 negative regulation of calcium ion transport 1 45 0.3782075
GO:BP GO:0006662 glycerol ether metabolic process 1 17 0.3798156
GO:BP GO:0046485 ether lipid metabolic process 1 17 0.3798156
GO:BP GO:0071496 cellular response to external stimulus 10 271 0.3798156
GO:BP GO:2000756 regulation of peptidyl-lysine acetylation 2 39 0.3798156
GO:BP GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 3 83 0.3804194
GO:BP GO:0006403 RNA localization 5 177 0.3804194
GO:BP GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle 1 20 0.3804194
GO:BP GO:0001754 eye photoreceptor cell differentiation 2 30 0.3804978
GO:BP GO:0061450 trophoblast cell migration 1 13 0.3811185
GO:BP GO:0001101 response to acid chemical 5 103 0.3811185
GO:BP GO:0002704 negative regulation of leukocyte mediated immunity 1 27 0.3811185
GO:BP GO:0043473 pigmentation 4 92 0.3811185
GO:BP GO:0002244 hematopoietic progenitor cell differentiation 5 108 0.3811185
GO:BP GO:0030859 polarized epithelial cell differentiation 1 20 0.3814747
GO:BP GO:2000758 positive regulation of peptidyl-lysine acetylation 1 22 0.3814747
GO:BP GO:0061339 establishment or maintenance of monopolar cell polarity 1 20 0.3814747
GO:BP GO:0032881 regulation of polysaccharide metabolic process 1 35 0.3815426
GO:BP GO:0002790 peptide secretion 2 172 0.3826631
GO:BP GO:2000116 regulation of cysteine-type endopeptidase activity 4 159 0.3828553
GO:BP GO:0032387 negative regulation of intracellular transport 3 48 0.3833126
GO:BP GO:0006497 protein lipidation 1 89 0.3833126
GO:BP GO:0046782 regulation of viral transcription 1 19 0.3833126
GO:BP GO:0042073 intraciliary transport 2 46 0.3833126
GO:BP GO:0032647 regulation of interferon-alpha production 1 19 0.3833126
GO:BP GO:0032607 interferon-alpha production 1 19 0.3833126
GO:BP GO:0010965 regulation of mitotic sister chromatid separation 1 56 0.3836547
GO:BP GO:2000117 negative regulation of cysteine-type endopeptidase activity 2 56 0.3837625
GO:BP GO:0017148 negative regulation of translation 4 175 0.3844464
GO:BP GO:0061323 cell proliferation involved in heart morphogenesis 1 18 0.3844808
GO:BP GO:0009263 deoxyribonucleotide biosynthetic process 1 13 0.3848849
GO:BP GO:0046385 deoxyribose phosphate biosynthetic process 1 13 0.3848849
GO:BP GO:0009265 2’-deoxyribonucleotide biosynthetic process 1 13 0.3848849
GO:BP GO:0031114 regulation of microtubule depolymerization 1 29 0.3850357
GO:BP GO:0014706 striated muscle tissue development 2 214 0.3861477
GO:BP GO:0048241 epinephrine transport 1 4 0.3863796
GO:BP GO:0035773 insulin secretion involved in cellular response to glucose stimulus 1 53 0.3865552
GO:BP GO:2001259 positive regulation of cation channel activity 1 50 0.3865552
GO:BP GO:0046349 amino sugar biosynthetic process 1 11 0.3870612
GO:BP GO:1904355 positive regulation of telomere capping 1 14 0.3871237
GO:BP GO:0006835 dicarboxylic acid transport 1 61 0.3871237
GO:BP GO:0071356 cellular response to tumor necrosis factor 3 159 0.3871237
GO:BP GO:0051924 regulation of calcium ion transport 2 167 0.3871975
GO:BP GO:0006188 IMP biosynthetic process 1 10 0.3873518
GO:BP GO:0060068 vagina development 1 8 0.3877224
GO:BP GO:0008090 retrograde axonal transport 1 20 0.3878667
GO:BP GO:0070344 regulation of fat cell proliferation 1 8 0.3879704
GO:BP GO:2000145 regulation of cell motility 4 741 0.3879704
GO:BP GO:0045161 neuronal ion channel clustering 1 8 0.3879704
GO:BP GO:0032966 negative regulation of collagen biosynthetic process 1 6 0.3879704
GO:BP GO:0046460 neutral lipid biosynthetic process 1 37 0.3880664
GO:BP GO:0006942 regulation of striated muscle contraction 1 84 0.3880664
GO:BP GO:0006468 protein phosphorylation 23 1131 0.3880664
GO:BP GO:0046463 acylglycerol biosynthetic process 1 37 0.3880664
GO:BP GO:0007281 germ cell development 1 194 0.3880664
GO:BP GO:1900095 regulation of dosage compensation by inactivation of X chromosome 1 13 0.3880664
GO:BP GO:0072175 epithelial tube formation 1 124 0.3882194
GO:BP GO:0046883 regulation of hormone secretion 2 170 0.3888545
GO:BP GO:0031529 ruffle organization 1 44 0.3894515
GO:BP GO:0030970 retrograde protein transport, ER to cytosol 1 28 0.3894515
GO:BP GO:1902750 negative regulation of cell cycle G2/M phase transition 3 62 0.3894515
GO:BP GO:0043069 negative regulation of programmed cell death 4 685 0.3894515
GO:BP GO:1903513 endoplasmic reticulum to cytosol transport 1 28 0.3894515
GO:BP GO:0060284 regulation of cell development 2 590 0.3894515
GO:BP GO:0032651 regulation of interleukin-1 beta production 2 48 0.3894515
GO:BP GO:0071398 cellular response to fatty acid 1 24 0.3894515
GO:BP GO:0051057 positive regulation of small GTPase mediated signal transduction 1 48 0.3894515
GO:BP GO:0031116 positive regulation of microtubule polymerization 1 31 0.3894515
GO:BP GO:0032611 interleukin-1 beta production 2 48 0.3894515
GO:BP GO:0007095 mitotic G2 DNA damage checkpoint signaling 2 35 0.3902699
GO:BP GO:0031398 positive regulation of protein ubiquitination 3 108 0.3904258
GO:BP GO:0045732 positive regulation of protein catabolic process 1 189 0.3914220
GO:BP GO:0042158 lipoprotein biosynthetic process 1 92 0.3914220
GO:BP GO:0045664 regulation of neuron differentiation 6 137 0.3915031
GO:BP GO:0051306 mitotic sister chromatid separation 1 59 0.3918888
GO:BP GO:0050728 negative regulation of inflammatory response 2 95 0.3919339
GO:BP GO:1904262 negative regulation of TORC1 signaling 1 24 0.3919339
GO:BP GO:0060627 regulation of vesicle-mediated transport 1 396 0.3919339
GO:BP GO:0036315 cellular response to sterol 1 15 0.3919339
GO:BP GO:0005978 glycogen biosynthetic process 1 40 0.3927151
GO:BP GO:0097400 interleukin-17-mediated signaling pathway 1 8 0.3927151
GO:BP GO:0009250 glucan biosynthetic process 1 40 0.3927151
GO:BP GO:0016322 neuron remodeling 1 12 0.3927151
GO:BP GO:0071044 histone mRNA catabolic process 1 11 0.3927151
GO:BP GO:1904029 regulation of cyclin-dependent protein kinase activity 3 87 0.3929684
GO:BP GO:0003073 regulation of systemic arterial blood pressure 1 62 0.3929684
GO:BP GO:0051952 regulation of amine transport 1 56 0.3929684
GO:BP GO:0003407 neural retina development 3 47 0.3930780
GO:BP GO:0099003 vesicle-mediated transport in synapse 2 180 0.3934006
GO:BP GO:0070647 protein modification by small protein conjugation or removal 6 869 0.3934006
GO:BP GO:0055007 cardiac muscle cell differentiation 1 108 0.3936145
GO:BP GO:0010764 negative regulation of fibroblast migration 1 10 0.3936145
GO:BP GO:0051784 negative regulation of nuclear division 1 56 0.3936145
GO:BP GO:0006098 pentose-phosphate shunt 1 19 0.3936145
GO:BP GO:0040019 positive regulation of embryonic development 1 17 0.3936145
GO:BP GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage 1 29 0.3936145
GO:BP GO:0030010 establishment of cell polarity 3 135 0.3936145
GO:BP GO:0006312 mitotic recombination 1 22 0.3936726
GO:BP GO:0045597 positive regulation of cell differentiation 2 616 0.3936726
GO:BP GO:0021695 cerebellar cortex development 1 43 0.3937525
GO:BP GO:0010739 positive regulation of protein kinase A signaling 1 7 0.3944309
GO:BP GO:0140354 lipid import into cell 1 16 0.3949799
GO:BP GO:0019538 protein metabolic process 17 4203 0.3950215
GO:BP GO:0002833 positive regulation of response to biotic stimulus 4 217 0.3950215
GO:BP GO:0043101 purine-containing compound salvage 1 14 0.3950215
GO:BP GO:0043009 chordate embryonic development 15 525 0.3953861
GO:BP GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 1 35 0.3958187
GO:BP GO:0120033 negative regulation of plasma membrane bounded cell projection assembly 1 27 0.3958187
GO:BP GO:2000278 regulation of DNA biosynthetic process 3 110 0.3960764
GO:BP GO:0009725 response to hormone 2 624 0.3963124
GO:BP GO:0033314 mitotic DNA replication checkpoint signaling 1 9 0.3963124
GO:BP GO:0070475 rRNA base methylation 1 8 0.3971740
GO:BP GO:0007100 mitotic centrosome separation 1 13 0.3973962
GO:BP GO:0031952 regulation of protein autophosphorylation 2 38 0.3973962
GO:BP GO:0043266 regulation of potassium ion transport 1 69 0.3983246
GO:BP GO:0071900 regulation of protein serine/threonine kinase activity 7 274 0.3990738
GO:BP GO:0043984 histone H4-K16 acetylation 1 14 0.4007655
GO:BP GO:0023057 negative regulation of signaling 21 1089 0.4007655
GO:BP GO:0002218 activation of innate immune response 5 166 0.4007655
GO:BP GO:0070252 actin-mediated cell contraction 1 90 0.4007655
GO:BP GO:0060415 muscle tissue morphogenesis 1 61 0.4007655
GO:BP GO:0036503 ERAD pathway 2 104 0.4007655
GO:BP GO:0015833 peptide transport 2 181 0.4007655
GO:BP GO:0006518 peptide metabolic process 15 781 0.4007655
GO:BP GO:1903573 negative regulation of response to endoplasmic reticulum stress 1 41 0.4007655
GO:BP GO:0043122 regulation of canonical NF-kappaB signal transduction 5 206 0.4007655
GO:BP GO:0006054 N-acetylneuraminate metabolic process 1 12 0.4007655
GO:BP GO:0035148 tube formation 1 133 0.4010324
GO:BP GO:0016024 CDP-diacylglycerol biosynthetic process 1 12 0.4018671
GO:BP GO:0043244 regulation of protein-containing complex disassembly 2 109 0.4018671
GO:BP GO:0050769 positive regulation of neurogenesis 1 189 0.4018671
GO:BP GO:0060079 excitatory postsynaptic potential 1 69 0.4018671
GO:BP GO:0035914 skeletal muscle cell differentiation 1 52 0.4018671
GO:BP GO:0090559 regulation of membrane permeability 1 62 0.4018671
GO:BP GO:0032413 negative regulation of ion transmembrane transporter activity 1 52 0.4018671
GO:BP GO:0045747 positive regulation of Notch signaling pathway 2 37 0.4018671
GO:BP GO:0060628 regulation of ER to Golgi vesicle-mediated transport 1 9 0.4018671
GO:BP GO:0009056 catabolic process 36 2106 0.4018671
GO:BP GO:0046341 CDP-diacylglycerol metabolic process 1 12 0.4018671
GO:BP GO:0045859 regulation of protein kinase activity 11 473 0.4018671
GO:BP GO:0043409 negative regulation of MAPK cascade 2 145 0.4018671
GO:BP GO:0071260 cellular response to mechanical stimulus 1 56 0.4018671
GO:BP GO:0010713 negative regulation of collagen metabolic process 1 7 0.4019494
GO:BP GO:0048706 embryonic skeletal system development 3 77 0.4019494
GO:BP GO:0007084 mitotic nuclear membrane reassembly 1 10 0.4019494
GO:BP GO:0010248 establishment or maintenance of transmembrane electrochemical gradient 1 7 0.4019494
GO:BP GO:0009126 purine nucleoside monophosphate metabolic process 2 38 0.4019494
GO:BP GO:0101024 mitotic nuclear membrane organization 1 10 0.4019494
GO:BP GO:0032481 positive regulation of type I interferon production 2 50 0.4019494
GO:BP GO:0052548 regulation of endopeptidase activity 5 220 0.4019494
GO:BP GO:0010165 response to X-ray 1 28 0.4019494
GO:BP GO:0048643 positive regulation of skeletal muscle tissue development 1 14 0.4026529
GO:BP GO:0045010 actin nucleation 1 49 0.4030829
GO:BP GO:0030252 growth hormone secretion 1 12 0.4032943
GO:BP GO:0090110 COPII-coated vesicle cargo loading 1 15 0.4032943
GO:BP GO:0097154 GABAergic neuron differentiation 1 7 0.4033895
GO:BP GO:0099188 postsynaptic cytoskeleton organization 1 17 0.4033895
GO:BP GO:0042574 retinal metabolic process 1 10 0.4033895
GO:BP GO:0015850 organic hydroxy compound transport 1 181 0.4033895
GO:BP GO:0016331 morphogenesis of embryonic epithelium 1 130 0.4041870
GO:BP GO:0048863 stem cell differentiation 1 196 0.4046350
GO:BP GO:0009913 epidermal cell differentiation 1 116 0.4046350
GO:BP GO:0040012 regulation of locomotion 4 762 0.4048947
GO:BP GO:0034260 negative regulation of GTPase activity 1 25 0.4050095
GO:BP GO:0000122 negative regulation of transcription by RNA polymerase II 18 744 0.4052248
GO:BP GO:0060291 long-term synaptic potentiation 1 66 0.4057551
GO:BP GO:0051568 histone H3-K4 methylation 2 41 0.4057551
GO:BP GO:0009151 purine deoxyribonucleotide metabolic process 1 12 0.4058391
GO:BP GO:0009404 toxin metabolic process 1 5 0.4062283
GO:BP GO:1902902 negative regulation of autophagosome assembly 1 12 0.4062692
GO:BP GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 1 211 0.4073063
GO:BP GO:0048667 cell morphogenesis involved in neuron differentiation 4 450 0.4079011
GO:BP GO:0045833 negative regulation of lipid metabolic process 1 74 0.4080166
GO:BP GO:0007264 small GTPase mediated signal transduction 1 414 0.4082021
GO:BP GO:0050708 regulation of protein secretion 2 185 0.4082021
GO:BP GO:0061484 hematopoietic stem cell homeostasis 1 20 0.4082642
GO:BP GO:0001825 blastocyst formation 2 37 0.4082642
GO:BP GO:0010001 glial cell differentiation 1 181 0.4088759
GO:BP GO:0051299 centrosome separation 1 14 0.4095167
GO:BP GO:0031112 positive regulation of microtubule polymerization or depolymerization 1 35 0.4096816
GO:BP GO:1903365 regulation of fear response 1 8 0.4099447
GO:BP GO:1901797 negative regulation of signal transduction by p53 class mediator 1 31 0.4099447
GO:BP GO:0051148 negative regulation of muscle cell differentiation 1 51 0.4099447
GO:BP GO:1902253 regulation of intrinsic apoptotic signaling pathway by p53 class mediator 1 32 0.4099447
GO:BP GO:0032543 mitochondrial translation 1 130 0.4099500
GO:BP GO:1903232 melanosome assembly 1 19 0.4099922
GO:BP GO:0001932 regulation of protein phosphorylation 16 758 0.4099922
GO:BP GO:0006360 transcription by RNA polymerase I 3 70 0.4099922
GO:BP GO:0098976 excitatory chemical synaptic transmission 1 8 0.4099922
GO:BP GO:1902742 apoptotic process involved in development 2 30 0.4099922
GO:BP GO:0016571 histone methylation 1 80 0.4105727
GO:BP GO:0048639 positive regulation of developmental growth 4 124 0.4105727
GO:BP GO:0051385 response to mineralocorticoid 1 20 0.4107500
GO:BP GO:0015837 amine transport 1 59 0.4107500
GO:BP GO:0042359 vitamin D metabolic process 1 9 0.4108903
GO:BP GO:0032879 regulation of localization 2 1568 0.4110883
GO:BP GO:0062208 positive regulation of pattern recognition receptor signaling pathway 1 43 0.4110883
GO:BP GO:0032872 regulation of stress-activated MAPK cascade 4 153 0.4112116
GO:BP GO:0061326 renal tubule development 2 78 0.4112811
GO:BP GO:0071216 cellular response to biotic stimulus 3 141 0.4112811
GO:BP GO:0015748 organophosphate ester transport 3 105 0.4116161
GO:BP GO:0035249 synaptic transmission, glutamatergic 1 65 0.4125631
GO:BP GO:0014061 regulation of norepinephrine secretion 1 5 0.4129937
GO:BP GO:0048243 norepinephrine secretion 1 5 0.4129937
GO:BP GO:0033604 negative regulation of catecholamine secretion 1 6 0.4129937
GO:BP GO:0009156 ribonucleoside monophosphate biosynthetic process 2 31 0.4139510
GO:BP GO:0031668 cellular response to extracellular stimulus 8 223 0.4139510
GO:BP GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 5 297 0.4141062
GO:BP GO:0008283 cell population proliferation 1 2339 0.4141062
GO:BP GO:0018904 ether metabolic process 1 21 0.4141062
GO:BP GO:0009642 response to light intensity 1 10 0.4141062
GO:BP GO:0050848 regulation of calcium-mediated signaling 1 51 0.4141062
GO:BP GO:0099565 chemical synaptic transmission, postsynaptic 1 74 0.4141062
GO:BP GO:0010459 negative regulation of heart rate 1 7 0.4141062
GO:BP GO:0018202 peptidyl-histidine modification 1 10 0.4141062
GO:BP GO:0001675 acrosome assembly 1 16 0.4141062
GO:BP GO:0060117 auditory receptor cell development 1 14 0.4141062
GO:BP GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity 1 10 0.4141062
GO:BP GO:0006167 AMP biosynthetic process 1 13 0.4141062
GO:BP GO:0000086 G2/M transition of mitotic cell cycle 5 130 0.4150820
GO:BP GO:0043604 amide biosynthetic process 15 786 0.4150820
GO:BP GO:0048644 muscle organ morphogenesis 1 64 0.4154123
GO:BP GO:0007611 learning or memory 5 200 0.4171960
GO:BP GO:1904263 positive regulation of TORC1 signaling 1 29 0.4171960
GO:BP GO:0060219 camera-type eye photoreceptor cell differentiation 1 18 0.4174422
GO:BP GO:0048563 post-embryonic animal organ morphogenesis 1 8 0.4177697
GO:BP GO:0003205 cardiac chamber development 1 150 0.4182745
GO:BP GO:0014842 regulation of skeletal muscle satellite cell proliferation 1 8 0.4183999
GO:BP GO:2000288 positive regulation of myoblast proliferation 1 9 0.4183999
GO:BP GO:0051965 positive regulation of synapse assembly 1 43 0.4188810
GO:BP GO:0033135 regulation of peptidyl-serine phosphorylation 3 97 0.4189249
GO:BP GO:0006740 NADPH regeneration 1 22 0.4189249
GO:BP GO:0045821 positive regulation of glycolytic process 1 16 0.4189249
GO:BP GO:1903706 regulation of hemopoiesis 1 265 0.4189249
GO:BP GO:0035023 regulation of Rho protein signal transduction 1 65 0.4189249
GO:BP GO:0098869 cellular oxidant detoxification 2 64 0.4191677
GO:BP GO:0061387 regulation of extent of cell growth 3 96 0.4191949
GO:BP GO:0032410 negative regulation of transporter activity 1 59 0.4191949
GO:BP GO:0033003 regulation of mast cell activation 1 24 0.4196173
GO:BP GO:0070534 protein K63-linked ubiquitination 3 62 0.4204138
GO:BP GO:0070365 hepatocyte differentiation 1 12 0.4211635
GO:BP GO:0033630 positive regulation of cell adhesion mediated by integrin 1 14 0.4211635
GO:BP GO:0001960 negative regulation of cytokine-mediated signaling pathway 2 52 0.4211635
GO:BP GO:0045913 positive regulation of carbohydrate metabolic process 2 61 0.4211635
GO:BP GO:0090385 phagosome-lysosome fusion 1 12 0.4211635
GO:BP GO:1901836 regulation of transcription of nucleolar large rRNA by RNA polymerase I 1 15 0.4211635
GO:BP GO:0009749 response to glucose 2 138 0.4211635
GO:BP GO:0070302 regulation of stress-activated protein kinase signaling cascade 4 157 0.4213624
GO:BP GO:0070723 response to cholesterol 1 17 0.4216257
GO:BP GO:0097049 motor neuron apoptotic process 1 18 0.4222503
GO:BP GO:0060042 retina morphogenesis in camera-type eye 2 40 0.4225140
GO:BP GO:1905818 regulation of chromosome separation 1 69 0.4225140
GO:BP GO:0000027 ribosomal large subunit assembly 1 25 0.4228473
GO:BP GO:0070131 positive regulation of mitochondrial translation 1 17 0.4229556
GO:BP GO:0043982 histone H4-K8 acetylation 1 16 0.4229556
GO:BP GO:0043981 histone H4-K5 acetylation 1 16 0.4229556
GO:BP GO:0043405 regulation of MAP kinase activity 2 141 0.4232114
GO:BP GO:0006749 glutathione metabolic process 1 41 0.4232114
GO:BP GO:0031111 negative regulation of microtubule polymerization or depolymerization 1 36 0.4235878
GO:BP GO:0061311 cell surface receptor signaling pathway involved in heart development 1 18 0.4235878
GO:BP GO:0009451 RNA modification 1 167 0.4242402
GO:BP GO:0010604 positive regulation of macromolecule metabolic process 49 2607 0.4243577
GO:BP GO:0002753 cytosolic pattern recognition receptor signaling pathway 2 98 0.4247088
GO:BP GO:1901989 positive regulation of cell cycle phase transition 3 101 0.4247088
GO:BP GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 2 27 0.4247958
GO:BP GO:0051336 regulation of hydrolase activity 2 680 0.4253506
GO:BP GO:0060338 regulation of type I interferon-mediated signaling pathway 1 35 0.4253506
GO:BP GO:0051253 negative regulation of RNA metabolic process 9 1111 0.4260777
GO:BP GO:0048729 tissue morphogenesis 1 501 0.4261752
GO:BP GO:0032024 positive regulation of insulin secretion 1 59 0.4261752
GO:BP GO:1901799 negative regulation of proteasomal protein catabolic process 1 47 0.4263743
GO:BP GO:0042327 positive regulation of phosphorylation 3 511 0.4263743
GO:BP GO:0030099 myeloid cell differentiation 1 304 0.4263743
GO:BP GO:0120255 olefinic compound biosynthetic process 1 18 0.4263743
GO:BP GO:1900544 positive regulation of purine nucleotide metabolic process 1 16 0.4270753
GO:BP GO:0045981 positive regulation of nucleotide metabolic process 1 16 0.4270753
GO:BP GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint 1 12 0.4270753
GO:BP GO:0090232 positive regulation of spindle checkpoint 1 12 0.4270753
GO:BP GO:0044060 regulation of endocrine process 1 24 0.4271228
GO:BP GO:0043173 nucleotide salvage 1 15 0.4271228
GO:BP GO:0006047 UDP-N-acetylglucosamine metabolic process 1 13 0.4271228
GO:BP GO:0034067 protein localization to Golgi apparatus 1 27 0.4271228
GO:BP GO:0009792 embryo development ending in birth or egg hatching 15 542 0.4277380
GO:BP GO:0006177 GMP biosynthetic process 1 13 0.4277380
GO:BP GO:2001135 regulation of endocytic recycling 1 17 0.4281698
GO:BP GO:0009746 response to hexose 2 139 0.4281698
GO:BP GO:0022030 telencephalon glial cell migration 1 22 0.4281698
GO:BP GO:0021801 cerebral cortex radial glia-guided migration 1 22 0.4281698
GO:BP GO:0001776 leukocyte homeostasis 4 73 0.4288994
GO:BP GO:0044281 small molecule metabolic process 1 1387 0.4288994
GO:BP GO:0021537 telencephalon development 1 208 0.4290882
GO:BP GO:0014733 regulation of skeletal muscle adaptation 1 11 0.4298810
GO:BP GO:0060603 mammary gland duct morphogenesis 1 28 0.4313907
GO:BP GO:0030032 lamellipodium assembly 1 59 0.4314140
GO:BP GO:0051238 sequestering of metal ion 1 7 0.4314140
GO:BP GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction 1 12 0.4314140
GO:BP GO:0035050 embryonic heart tube development 3 69 0.4316614
GO:BP GO:0034249 negative regulation of amide metabolic process 2 196 0.4326453
GO:BP GO:1901030 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 12 0.4326453
GO:BP GO:0006631 fatty acid metabolic process 1 277 0.4326453
GO:BP GO:0001818 negative regulation of cytokine production 4 171 0.4326453
GO:BP GO:1904063 negative regulation of cation transmembrane transport 1 64 0.4326453
GO:BP GO:0010225 response to UV-C 1 13 0.4326453
GO:BP GO:0034394 protein localization to cell surface 1 60 0.4330131
GO:BP GO:0048598 embryonic morphogenesis 2 438 0.4334312
GO:BP GO:0009968 negative regulation of signal transduction 19 1016 0.4335233
GO:BP GO:0006222 UMP biosynthetic process 1 9 0.4339887
GO:BP GO:0090596 sensory organ morphogenesis 1 179 0.4349546
GO:BP GO:1903543 positive regulation of exosomal secretion 1 13 0.4349546
GO:BP GO:0010587 miRNA catabolic process 1 12 0.4358166
GO:BP GO:1901863 positive regulation of muscle tissue development 1 18 0.4358166
GO:BP GO:0051962 positive regulation of nervous system development 1 221 0.4358166
GO:BP GO:0006778 porphyrin-containing compound metabolic process 2 43 0.4358490
GO:BP GO:0003014 renal system process 1 76 0.4358490
GO:BP GO:1903532 positive regulation of secretion by cell 2 198 0.4364699
GO:BP GO:0009790 embryo development 3 859 0.4370599
GO:BP GO:0009410 response to xenobiotic stimulus 7 275 0.4370599
GO:BP GO:0001910 regulation of leukocyte mediated cytotoxicity 1 36 0.4378918
GO:BP GO:0090317 negative regulation of intracellular protein transport 2 37 0.4378918
GO:BP GO:0010907 positive regulation of glucose metabolic process 1 37 0.4378918
GO:BP GO:0048384 retinoic acid receptor signaling pathway 1 27 0.4378918
GO:BP GO:0048588 developmental cell growth 2 194 0.4378918
GO:BP GO:0001763 morphogenesis of a branching structure 5 155 0.4380333
GO:BP GO:0009966 regulation of signal transduction 42 2270 0.4382701
GO:BP GO:0060761 negative regulation of response to cytokine stimulus 2 56 0.4382701
GO:BP GO:0007249 canonical NF-kappaB signal transduction 1 232 0.4397041
GO:BP GO:0071359 cellular response to dsRNA 1 18 0.4397041
GO:BP GO:0032652 regulation of interleukin-1 production 2 56 0.4397041
GO:BP GO:0032612 interleukin-1 production 2 56 0.4397041
GO:BP GO:1901984 negative regulation of protein acetylation 1 13 0.4397041
GO:BP GO:0022412 cellular process involved in reproduction in multicellular organism 1 255 0.4397041
GO:BP GO:2000050 regulation of non-canonical Wnt signaling pathway 1 23 0.4397041
GO:BP GO:0036065 fucosylation 1 10 0.4398951
GO:BP GO:0002327 immature B cell differentiation 1 11 0.4398951
GO:BP GO:0035051 cardiocyte differentiation 1 134 0.4398951
GO:BP GO:0071466 cellular response to xenobiotic stimulus 2 108 0.4408352
GO:BP GO:0031329 regulation of cellular catabolic process 10 562 0.4408352
GO:BP GO:0006607 NLS-bearing protein import into nucleus 1 18 0.4408352
GO:BP GO:0046348 amino sugar catabolic process 1 10 0.4408352
GO:BP GO:0090162 establishment of epithelial cell polarity 1 30 0.4408352
GO:BP GO:0048754 branching morphogenesis of an epithelial tube 3 121 0.4408352
GO:BP GO:0051452 intracellular pH reduction 1 46 0.4408352
GO:BP GO:0034284 response to monosaccharide 2 143 0.4408352
GO:BP GO:0043300 regulation of leukocyte degranulation 1 26 0.4408352
GO:BP GO:0042594 response to starvation 4 176 0.4408352
GO:BP GO:0042593 glucose homeostasis 3 172 0.4408352
GO:BP GO:0140053 mitochondrial gene expression 4 162 0.4408352
GO:BP GO:0071230 cellular response to amino acid stimulus 3 66 0.4423828
GO:BP GO:0051051 negative regulation of transport 5 317 0.4423828
GO:BP GO:0071549 cellular response to dexamethasone stimulus 1 23 0.4423828
GO:BP GO:0021952 central nervous system projection neuron axonogenesis 1 24 0.4423828
GO:BP GO:0016477 cell migration 5 1064 0.4423828
GO:BP GO:0048641 regulation of skeletal muscle tissue development 1 19 0.4423828
GO:BP GO:0003012 muscle system process 2 334 0.4423828
GO:BP GO:0033500 carbohydrate homeostasis 3 173 0.4423828
GO:BP GO:0043254 regulation of protein-containing complex assembly 2 340 0.4424144
GO:BP GO:0032368 regulation of lipid transport 2 91 0.4424144
GO:BP GO:0030048 actin filament-based movement 1 111 0.4425202
GO:BP GO:0010821 regulation of mitochondrion organization 1 133 0.4429324
GO:BP GO:0006810 transport 2 3295 0.4431982
GO:BP GO:0060623 regulation of chromosome condensation 1 12 0.4444774
GO:BP GO:2000773 negative regulation of cellular senescence 1 19 0.4444774
GO:BP GO:0010243 response to organonitrogen compound 1 765 0.4444774
GO:BP GO:0048812 neuron projection morphogenesis 2 499 0.4444774
GO:BP GO:0006970 response to osmotic stress 2 64 0.4450705
GO:BP GO:1901019 regulation of calcium ion transmembrane transporter activity 1 70 0.4450705
GO:BP GO:0002709 regulation of T cell mediated immunity 1 45 0.4450705
GO:BP GO:0021772 olfactory bulb development 1 20 0.4458843
GO:BP GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response 1 13 0.4469963
GO:BP GO:0010524 positive regulation of calcium ion transport into cytosol 1 7 0.4469963
GO:BP GO:1901841 regulation of high voltage-gated calcium channel activity 1 12 0.4469963
GO:BP GO:0051280 negative regulation of release of sequestered calcium ion into cytosol 1 11 0.4469963
GO:BP GO:0099638 endosome to plasma membrane protein transport 1 15 0.4469963
GO:BP GO:0016043 cellular component organization 6 5116 0.4469963
GO:BP GO:0032720 negative regulation of tumor necrosis factor production 1 32 0.4473237
GO:BP GO:0046879 hormone secretion 2 211 0.4473237
GO:BP GO:0070341 fat cell proliferation 1 11 0.4476804
GO:BP GO:0000288 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 1 64 0.4490342
GO:BP GO:0002090 regulation of receptor internalization 1 50 0.4490342
GO:BP GO:0045087 innate immune response 2 516 0.4497815
GO:BP GO:0044419 biological process involved in interspecies interaction between organisms 3 988 0.4500500
GO:BP GO:0034766 negative regulation of monoatomic ion transmembrane transport 1 70 0.4501779
GO:BP GO:0009174 pyrimidine ribonucleoside monophosphate biosynthetic process 1 10 0.4520366
GO:BP GO:0046530 photoreceptor cell differentiation 2 40 0.4520366
GO:BP GO:0060048 cardiac muscle contraction 1 121 0.4520366
GO:BP GO:0090287 regulation of cellular response to growth factor stimulus 1 261 0.4522134
GO:BP GO:0002520 immune system development 1 144 0.4533885
GO:BP GO:0042307 positive regulation of protein import into nucleus 1 33 0.4546338
GO:BP GO:0120039 plasma membrane bounded cell projection morphogenesis 2 514 0.4553611
GO:BP GO:0007368 determination of left/right symmetry 4 96 0.4555867
GO:BP GO:0033233 regulation of protein sumoylation 1 21 0.4567194
GO:BP GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 1 33 0.4567845
GO:BP GO:0051403 stress-activated MAPK cascade 5 188 0.4574982
GO:BP GO:0043588 skin development 1 179 0.4581143
GO:BP GO:0017145 stem cell division 1 25 0.4581175
GO:BP GO:0031644 regulation of nervous system process 1 87 0.4585746
GO:BP GO:0048858 cell projection morphogenesis 2 518 0.4587326
GO:BP GO:1905953 negative regulation of lipid localization 1 31 0.4588891
GO:BP GO:0043923 positive regulation by host of viral transcription 1 18 0.4592765
GO:BP GO:0006366 transcription by RNA polymerase II 24 1851 0.4592765
GO:BP GO:0021988 olfactory lobe development 1 22 0.4592765
GO:BP GO:0038095 Fc-epsilon receptor signaling pathway 1 17 0.4592765
GO:BP GO:0046339 diacylglycerol metabolic process 1 24 0.4592765
GO:BP GO:0032880 regulation of protein localization 1 718 0.4592765
GO:BP GO:0019751 polyol metabolic process 1 82 0.4592765
GO:BP GO:0043248 proteasome assembly 1 14 0.4592765
GO:BP GO:0044403 biological process involved in symbiotic interaction 1 225 0.4592765
GO:BP GO:0051345 positive regulation of hydrolase activity 1 412 0.4596026
GO:BP GO:1901096 regulation of autophagosome maturation 1 16 0.4596026
GO:BP GO:0006644 phospholipid metabolic process 9 307 0.4596026
GO:BP GO:0060560 developmental growth involved in morphogenesis 2 207 0.4596026
GO:BP GO:0099170 postsynaptic modulation of chemical synaptic transmission 1 22 0.4596026
GO:BP GO:0036314 response to sterol 1 20 0.4596026
GO:BP GO:0000271 polysaccharide biosynthetic process 1 54 0.4596026
GO:BP GO:0018216 peptidyl-arginine methylation 1 14 0.4601494
GO:BP GO:0006515 protein quality control for misfolded or incompletely synthesized proteins 1 31 0.4607470
GO:BP GO:0009914 hormone transport 2 216 0.4612911
GO:BP GO:1903541 regulation of exosomal secretion 1 15 0.4616490
GO:BP GO:1901698 response to nitrogen compound 1 810 0.4616490
GO:BP GO:0051234 establishment of localization 2 3454 0.4619455
GO:BP GO:0042596 fear response 2 33 0.4624596
GO:BP GO:0055075 potassium ion homeostasis 1 22 0.4624596
GO:BP GO:0061099 negative regulation of protein tyrosine kinase activity 1 23 0.4624680
GO:BP GO:0045088 regulation of innate immune response 4 261 0.4626478
GO:BP GO:0046889 positive regulation of lipid biosynthetic process 2 64 0.4626478
GO:BP GO:0031145 anaphase-promoting complex-dependent catabolic process 1 23 0.4626478
GO:BP GO:0140374 antiviral innate immune response 1 35 0.4626478
GO:BP GO:0048545 response to steroid hormone 1 237 0.4626478
GO:BP GO:0009887 animal organ morphogenesis 2 725 0.4626616
GO:BP GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 13 0.4628527
GO:BP GO:0045806 negative regulation of endocytosis 1 56 0.4628594
GO:BP GO:0009581 detection of external stimulus 1 66 0.4629291
GO:BP GO:0051222 positive regulation of protein transport 2 245 0.4636468
GO:BP GO:0033559 unsaturated fatty acid metabolic process 2 67 0.4636468
GO:BP GO:1905897 regulation of response to endoplasmic reticulum stress 3 76 0.4636468
GO:BP GO:1901077 regulation of relaxation of muscle 1 8 0.4636468
GO:BP GO:0046467 membrane lipid biosynthetic process 1 124 0.4646030
GO:BP GO:1903531 negative regulation of secretion by cell 2 101 0.4647265
GO:BP GO:2000232 regulation of rRNA processing 1 16 0.4651331
GO:BP GO:0097091 synaptic vesicle clustering 1 16 0.4662453
GO:BP GO:0043269 regulation of monoatomic ion transport 3 369 0.4665037
GO:BP GO:0035296 regulation of tube diameter 1 98 0.4665037
GO:BP GO:0097746 blood vessel diameter maintenance 1 98 0.4665037
GO:BP GO:0043303 mast cell degranulation 1 29 0.4665037
GO:BP GO:0010557 positive regulation of macromolecule biosynthetic process 11 1895 0.4665037
GO:BP GO:1901976 regulation of cell cycle checkpoint 1 43 0.4665037
GO:BP GO:0042308 negative regulation of protein import into nucleus 1 13 0.4665037
GO:BP GO:0009582 detection of abiotic stimulus 1 67 0.4674849
GO:BP GO:0042063 gliogenesis 1 244 0.4674849
GO:BP GO:0032990 cell part morphogenesis 2 538 0.4674849
GO:BP GO:0060078 regulation of postsynaptic membrane potential 1 85 0.4674849
GO:BP GO:0035150 regulation of tube size 1 98 0.4674849
GO:BP GO:0007041 lysosomal transport 4 114 0.4675004
GO:BP GO:0051156 glucose 6-phosphate metabolic process 1 25 0.4681940
GO:BP GO:0010800 positive regulation of peptidyl-threonine phosphorylation 1 23 0.4681940
GO:BP GO:0007283 spermatogenesis 5 333 0.4682453
GO:BP GO:2000379 positive regulation of reactive oxygen species metabolic process 1 45 0.4682453
GO:BP GO:0097421 liver regeneration 1 23 0.4682453
GO:BP GO:0006801 superoxide metabolic process 1 41 0.4682453
GO:BP GO:0045937 positive regulation of phosphate metabolic process 3 559 0.4684691
GO:BP GO:0010562 positive regulation of phosphorus metabolic process 3 559 0.4684691
GO:BP GO:2000272 negative regulation of signaling receptor activity 1 22 0.4685371
GO:BP GO:0050775 positive regulation of dendrite morphogenesis 1 32 0.4685371
GO:BP GO:0031341 regulation of cell killing 1 40 0.4685371
GO:BP GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process 2 92 0.4685371
GO:BP GO:0010648 negative regulation of cell communication 20 1087 0.4685371
GO:BP GO:0006337 nucleosome disassembly 1 15 0.4685371
GO:BP GO:1904062 regulation of monoatomic cation transmembrane transport 2 232 0.4687869
GO:BP GO:0015868 purine ribonucleotide transport 1 23 0.4687869
GO:BP GO:0001768 establishment of T cell polarity 1 10 0.4691072
GO:BP GO:0140353 lipid export from cell 1 28 0.4698229
GO:BP GO:1990138 neuron projection extension 4 149 0.4698229
GO:BP GO:0048675 axon extension 3 108 0.4704552
GO:BP GO:0006865 amino acid transport 1 103 0.4712148
GO:BP GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 1 53 0.4712148
GO:BP GO:0038034 signal transduction in absence of ligand 1 53 0.4712148
GO:BP GO:0000281 mitotic cytokinesis 2 83 0.4713140
GO:BP GO:0051153 regulation of striated muscle cell differentiation 1 66 0.4716722
GO:BP GO:0032940 secretion by cell 4 572 0.4720194
GO:BP GO:1902531 regulation of intracellular signal transduction 25 1317 0.4720194
GO:BP GO:0032365 intracellular lipid transport 1 43 0.4720194
GO:BP GO:0045842 positive regulation of mitotic metaphase/anaphase transition 1 14 0.4730291
GO:BP GO:0002279 mast cell activation involved in immune response 1 30 0.4731253
GO:BP GO:0045022 early endosome to late endosome transport 2 42 0.4731253
GO:BP GO:0071840 cellular component organization or biogenesis 6 5317 0.4731253
GO:BP GO:0014074 response to purine-containing compound 1 108 0.4744307
GO:BP GO:0097306 cellular response to alcohol 2 72 0.4744906
GO:BP GO:0045934 negative regulation of nucleobase-containing compound metabolic process 1 1203 0.4762819
GO:BP GO:0031098 stress-activated protein kinase signaling cascade 5 194 0.4765355
GO:BP GO:0090263 positive regulation of canonical Wnt signaling pathway 2 90 0.4772417
GO:BP GO:0071577 zinc ion transmembrane transport 1 22 0.4773484
GO:BP GO:2000291 regulation of myoblast proliferation 1 11 0.4773700
GO:BP GO:0014857 regulation of skeletal muscle cell proliferation 1 10 0.4773700
GO:BP GO:0043010 camera-type eye development 1 237 0.4779426
GO:BP GO:0050872 white fat cell differentiation 1 15 0.4780143
GO:BP GO:0002448 mast cell mediated immunity 1 32 0.4780143
GO:BP GO:0051284 positive regulation of sequestering of calcium ion 1 13 0.4783635
GO:BP GO:0021954 central nervous system neuron development 2 64 0.4783635
GO:BP GO:0060972 left/right pattern formation 4 101 0.4783635
GO:BP GO:0071347 cellular response to interleukin-1 1 64 0.4789895
GO:BP GO:0010761 fibroblast migration 2 52 0.4789895
GO:BP GO:0099072 regulation of postsynaptic membrane neurotransmitter receptor levels 1 72 0.4789895
GO:BP GO:0055085 transmembrane transport 1 1016 0.4794424
GO:BP GO:0009743 response to carbohydrate 2 161 0.4794424
GO:BP GO:0090277 positive regulation of peptide hormone secretion 1 72 0.4794424
GO:BP GO:0039531 regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway 1 67 0.4797750
GO:BP GO:0006044 N-acetylglucosamine metabolic process 1 16 0.4801175
GO:BP GO:1900226 negative regulation of NLRP3 inflammasome complex assembly 1 9 0.4801175
GO:BP GO:1904951 positive regulation of establishment of protein localization 2 261 0.4801175
GO:BP GO:0044839 cell cycle G2/M phase transition 5 145 0.4801175
GO:BP GO:0009893 positive regulation of metabolic process 52 2846 0.4801175
GO:BP GO:0060429 epithelium development 3 847 0.4801175
GO:BP GO:0046112 nucleobase biosynthetic process 1 18 0.4801175
GO:BP GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 1 16 0.4801175
GO:BP GO:0046040 IMP metabolic process 1 15 0.4801175
GO:BP GO:0002098 tRNA wobble uridine modification 1 16 0.4801175
GO:BP GO:0070373 negative regulation of ERK1 and ERK2 cascade 1 58 0.4802211
GO:BP GO:0097581 lamellipodium organization 1 77 0.4802211
GO:BP GO:0010770 positive regulation of cell morphogenesis 1 33 0.4804555
GO:BP GO:1900102 negative regulation of endoplasmic reticulum unfolded protein response 1 16 0.4812054
GO:BP GO:0060341 regulation of cellular localization 1 804 0.4823726
GO:BP GO:0001767 establishment of lymphocyte polarity 1 11 0.4836923
GO:BP GO:0045744 negative regulation of G protein-coupled receptor signaling pathway 1 36 0.4836923
GO:BP GO:0097398 cellular response to interleukin-17 1 12 0.4836923
GO:BP GO:0040008 regulation of growth 13 493 0.4836923
GO:BP GO:0098815 modulation of excitatory postsynaptic potential 2 44 0.4836923
GO:BP GO:0023035 CD40 signaling pathway 1 11 0.4836923
GO:BP GO:0006829 zinc ion transport 1 23 0.4841700
GO:BP GO:0071229 cellular response to acid chemical 3 72 0.4843451
GO:BP GO:1990748 cellular detoxification 2 79 0.4848154
GO:BP GO:0032414 positive regulation of ion transmembrane transporter activity 1 83 0.4848154
GO:BP GO:0002886 regulation of myeloid leukocyte mediated immunity 1 32 0.4848154
GO:BP GO:0045944 positive regulation of transcription by RNA polymerase II 3 915 0.4852011
GO:BP GO:0070542 response to fatty acid 1 38 0.4857622
GO:BP GO:0006878 intracellular copper ion homeostasis 1 15 0.4857622
GO:BP GO:0048232 male gamete generation 5 346 0.4857622
GO:BP GO:0045773 positive regulation of axon extension 1 32 0.4877132
GO:BP GO:1902101 positive regulation of metaphase/anaphase transition of cell cycle 1 14 0.4877132
GO:BP GO:0021799 cerebral cortex radially oriented cell migration 1 28 0.4877132
GO:BP GO:0007186 G protein-coupled receptor signaling pathway 1 387 0.4883930
GO:BP GO:0009162 deoxyribonucleoside monophosphate metabolic process 1 18 0.4883930
GO:BP GO:0000422 autophagy of mitochondrion 1 90 0.4885481
GO:BP GO:0061726 mitochondrion disassembly 1 90 0.4885481
GO:BP GO:0050905 neuromuscular process 3 110 0.4885630
GO:BP GO:0035640 exploration behavior 1 21 0.4888796
GO:BP GO:0033013 tetrapyrrole metabolic process 2 51 0.4890063
GO:BP GO:1902904 negative regulation of supramolecular fiber organization 2 136 0.4890063
GO:BP GO:0010738 regulation of protein kinase A signaling 1 13 0.4892507
GO:BP GO:0010669 epithelial structure maintenance 1 15 0.4892507
GO:BP GO:0010842 retina layer formation 1 16 0.4892507
GO:BP GO:0046321 positive regulation of fatty acid oxidation 1 15 0.4892507
GO:BP GO:0051503 adenine nucleotide transport 1 25 0.4892507
GO:BP GO:0014841 skeletal muscle satellite cell proliferation 1 13 0.4892507
GO:BP GO:0060914 heart formation 1 28 0.4892507
GO:BP GO:0061640 cytoskeleton-dependent cytokinesis 3 106 0.4892507
GO:BP GO:0005977 glycogen metabolic process 1 64 0.4892507
GO:BP GO:0061462 protein localization to lysosome 2 47 0.4892507
GO:BP GO:0045063 T-helper 1 cell differentiation 1 15 0.4892507
GO:BP GO:0006690 icosanoid metabolic process 2 60 0.4895604
GO:BP GO:0006869 lipid transport 1 269 0.4895604
GO:BP GO:0032527 protein exit from endoplasmic reticulum 1 43 0.4895604
GO:BP GO:0032986 protein-DNA complex disassembly 1 17 0.4896535
GO:BP GO:0042790 nucleolar large rRNA transcription by RNA polymerase I 1 21 0.4896535
GO:BP GO:0006826 iron ion transport 1 42 0.4898376
GO:BP GO:0031113 regulation of microtubule polymerization 1 51 0.4905610
GO:BP GO:0009226 nucleotide-sugar biosynthetic process 1 19 0.4905610
GO:BP GO:0032088 negative regulation of NF-kappaB transcription factor activity 2 66 0.4908343
GO:BP GO:0042994 cytoplasmic sequestering of transcription factor 1 15 0.4908343
GO:BP GO:0070588 calcium ion transmembrane transport 2 221 0.4908495
GO:BP GO:0009168 purine ribonucleoside monophosphate biosynthetic process 1 18 0.4911232
GO:BP GO:0006937 regulation of muscle contraction 1 130 0.4912122
GO:BP GO:0070979 protein K11-linked ubiquitination 1 29 0.4912122
GO:BP GO:0046475 glycerophospholipid catabolic process 1 21 0.4912122
GO:BP GO:0055088 lipid homeostasis 1 116 0.4912122
GO:BP GO:0048854 brain morphogenesis 1 27 0.4913180
GO:BP GO:0042886 amide transport 2 236 0.4913293
GO:BP GO:0045862 positive regulation of proteolysis 1 289 0.4914059
GO:BP GO:0046890 regulation of lipid biosynthetic process 2 136 0.4914059
GO:BP GO:0042221 response to chemical 2 2455 0.4914059
GO:BP GO:0042058 regulation of epidermal growth factor receptor signaling pathway 2 53 0.4914059
GO:BP GO:1903020 positive regulation of glycoprotein metabolic process 1 17 0.4914059
GO:BP GO:0045926 negative regulation of growth 5 204 0.4921146
GO:BP GO:0009266 response to temperature stimulus 1 122 0.4921146
GO:BP GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 1 37 0.4930329
GO:BP GO:0006633 fatty acid biosynthetic process 2 106 0.4934804
GO:BP GO:0032012 regulation of ARF protein signal transduction 1 18 0.4935099
GO:BP GO:0032011 ARF protein signal transduction 1 18 0.4935099
GO:BP GO:0051101 regulation of DNA binding 2 102 0.4935099
GO:BP GO:1990182 exosomal secretion 1 18 0.4935099
GO:BP GO:0044042 glucan metabolic process 1 65 0.4936925
GO:BP GO:0097062 dendritic spine maintenance 1 16 0.4938851
GO:BP GO:0050767 regulation of neurogenesis 1 300 0.4940053
GO:BP GO:0045332 phospholipid translocation 1 32 0.4940053
GO:BP GO:0018195 peptidyl-arginine modification 1 17 0.4940053
GO:BP GO:0097396 response to interleukin-17 1 13 0.4949210
GO:BP GO:0040011 locomotion 4 854 0.4957162
GO:BP GO:0002698 negative regulation of immune effector process 1 59 0.4960745
GO:BP GO:0098927 vesicle-mediated transport between endosomal compartments 2 44 0.4960745
GO:BP GO:0031345 negative regulation of cell projection organization 4 154 0.4960745
GO:BP GO:0006006 glucose metabolic process 1 153 0.4969547
GO:BP GO:0140352 export from cell 1 616 0.4970269
GO:BP GO:0031328 positive regulation of cellular biosynthetic process 11 1957 0.4974335
GO:BP GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process 1 13 0.4974335
GO:BP GO:0008544 epidermis development 1 213 0.4974335
GO:BP GO:0046049 UMP metabolic process 1 11 0.4974335
GO:BP GO:0048704 embryonic skeletal system morphogenesis 2 54 0.4974335
GO:BP GO:0006805 xenobiotic metabolic process 2 56 0.4974335
GO:BP GO:0099560 synaptic membrane adhesion 1 21 0.4975703
GO:BP GO:0051048 negative regulation of secretion 1 111 0.4993120
GO:BP GO:0009123 nucleoside monophosphate metabolic process 3 64 0.4993120
GO:BP GO:1903859 regulation of dendrite extension 1 18 0.4995749
GO:BP GO:0009886 post-embryonic animal morphogenesis 1 11 0.5003485
GO:BP GO:0015865 purine nucleotide transport 1 25 0.5008431
GO:BP GO:0033189 response to vitamin A 1 13 0.5013050
GO:BP GO:0099587 inorganic ion import across plasma membrane 1 71 0.5023993
GO:BP GO:0002456 T cell mediated immunity 1 61 0.5023993
GO:BP GO:0098659 inorganic cation import across plasma membrane 1 71 0.5023993
GO:BP GO:0010839 negative regulation of keratinocyte proliferation 1 19 0.5024371
GO:BP GO:0006144 purine nucleobase metabolic process 1 15 0.5024371
GO:BP GO:0006699 bile acid biosynthetic process 1 26 0.5026046
GO:BP GO:0060986 endocrine hormone secretion 1 35 0.5026572
GO:BP GO:0021955 central nervous system neuron axonogenesis 1 33 0.5026572
GO:BP GO:0060999 positive regulation of dendritic spine development 1 37 0.5026572
GO:BP GO:0045912 negative regulation of carbohydrate metabolic process 1 41 0.5026572
GO:BP GO:0052547 regulation of peptidase activity 1 265 0.5027930
GO:BP GO:0046165 alcohol biosynthetic process 1 111 0.5034777
GO:BP GO:0010649 regulation of cell communication by electrical coupling 1 17 0.5040069
GO:BP GO:0060562 epithelial tube morphogenesis 5 276 0.5048971
GO:BP GO:0050806 positive regulation of synaptic transmission 1 110 0.5051332
GO:BP GO:0097734 extracellular exosome biogenesis 1 18 0.5051332
GO:BP GO:0009891 positive regulation of biosynthetic process 11 1971 0.5059076
GO:BP GO:0008610 lipid biosynthetic process 11 563 0.5062848
GO:BP GO:0034219 carbohydrate transmembrane transport 4 95 0.5063256
GO:BP GO:0007006 mitochondrial membrane organization 1 112 0.5064017
GO:BP GO:0061709 reticulophagy 1 18 0.5064017
GO:BP GO:1905952 regulation of lipid localization 2 110 0.5064017
GO:BP GO:0001654 eye development 1 273 0.5066868
GO:BP GO:0060443 mammary gland morphogenesis 1 39 0.5073193
GO:BP GO:0032411 positive regulation of transporter activity 1 93 0.5075022
GO:BP GO:0021675 nerve development 1 63 0.5075022
GO:BP GO:0007417 central nervous system development 15 749 0.5075022
GO:BP GO:0034763 negative regulation of transmembrane transport 1 96 0.5075022
GO:BP GO:0043271 negative regulation of monoatomic ion transport 1 88 0.5075022
GO:BP GO:0055082 intracellular chemical homeostasis 5 498 0.5075549
GO:BP GO:0141086 negative regulation of inflammasome-mediated signaling pathway 1 10 0.5081706
GO:BP GO:0032230 positive regulation of synaptic transmission, GABAergic 1 10 0.5081706
GO:BP GO:0150063 visual system development 1 274 0.5088515
GO:BP GO:0051928 positive regulation of calcium ion transport 1 80 0.5093679
GO:BP GO:0010720 positive regulation of cell development 3 317 0.5093679
GO:BP GO:0006796 phosphate-containing compound metabolic process 37 2096 0.5103480
GO:BP GO:0098609 cell-cell adhesion 1 599 0.5113950
GO:BP GO:0097237 cellular response to toxic substance 2 85 0.5116384
GO:BP GO:0030520 intracellular estrogen receptor signaling pathway 2 41 0.5117837
GO:BP GO:0070129 regulation of mitochondrial translation 1 26 0.5120881
GO:BP GO:1900044 regulation of protein K63-linked ubiquitination 1 15 0.5121243
GO:BP GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 1 103 0.5121243
GO:BP GO:0035795 negative regulation of mitochondrial membrane permeability 1 17 0.5121243
GO:BP GO:0046627 negative regulation of insulin receptor signaling pathway 1 31 0.5121243
GO:BP GO:0030540 female genitalia development 1 14 0.5121243
GO:BP GO:0043277 apoptotic cell clearance 2 32 0.5121243
GO:BP GO:0040020 regulation of meiotic nuclear division 1 19 0.5121243
GO:BP GO:0097202 activation of cysteine-type endopeptidase activity 1 16 0.5121243
GO:BP GO:0010876 lipid localization 1 307 0.5121243
GO:BP GO:1901978 positive regulation of cell cycle checkpoint 1 18 0.5121243
GO:BP GO:1902916 positive regulation of protein polyubiquitination 1 13 0.5121243
GO:BP GO:0048880 sensory system development 1 276 0.5121243
GO:BP GO:0048873 homeostasis of number of cells within a tissue 1 25 0.5121243
GO:BP GO:0060395 SMAD protein signal transduction 1 64 0.5121243
GO:BP GO:0030900 forebrain development 1 290 0.5126938
GO:BP GO:0031347 regulation of defense response 5 476 0.5137264
GO:BP GO:0061001 regulation of dendritic spine morphogenesis 1 37 0.5137264
GO:BP GO:0031053 primary miRNA processing 1 18 0.5137264
GO:BP GO:0046903 secretion 1 646 0.5138645
GO:BP GO:0009306 protein secretion 2 261 0.5155965
GO:BP GO:0034204 lipid translocation 1 37 0.5158350
GO:BP GO:0007566 embryo implantation 2 40 0.5164322
GO:BP GO:0097094 craniofacial suture morphogenesis 1 15 0.5166327
GO:BP GO:0035592 establishment of protein localization to extracellular region 2 261 0.5166374
GO:BP GO:0006941 striated muscle contraction 1 153 0.5166615
GO:BP GO:2001056 positive regulation of cysteine-type endopeptidase activity 2 103 0.5169210
GO:BP GO:0008210 estrogen metabolic process 1 16 0.5171100
GO:BP GO:0002097 tRNA wobble base modification 1 19 0.5171100
GO:BP GO:0099504 synaptic vesicle cycle 6 162 0.5179145
GO:BP GO:0007266 Rho protein signal transduction 1 107 0.5179145
GO:BP GO:1900077 negative regulation of cellular response to insulin stimulus 1 32 0.5188358
GO:BP GO:0045576 mast cell activation 1 34 0.5188358
GO:BP GO:1901655 cellular response to ketone 2 82 0.5193347
GO:BP GO:0001659 temperature homeostasis 1 134 0.5218109
GO:BP GO:0048535 lymph node development 1 11 0.5221141
GO:BP GO:0061008 hepaticobiliary system development 4 113 0.5221141
GO:BP GO:0048524 positive regulation of viral process 2 55 0.5221256
GO:BP GO:0040014 regulation of multicellular organism growth 1 53 0.5222301
GO:BP GO:0045787 positive regulation of cell cycle 7 272 0.5222301
GO:BP GO:0048646 anatomical structure formation involved in morphogenesis 5 868 0.5227296
GO:BP GO:0007088 regulation of mitotic nuclear division 1 99 0.5228240
GO:BP GO:0045190 isotype switching 1 40 0.5234035
GO:BP GO:0002208 somatic diversification of immunoglobulins involved in immune response 1 40 0.5234035
GO:BP GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 1 40 0.5234035
GO:BP GO:0061138 morphogenesis of a branching epithelium 3 143 0.5234035
GO:BP GO:0098754 detoxification 2 87 0.5234317
GO:BP GO:0043616 keratinocyte proliferation 2 39 0.5234317
GO:BP GO:0055070 copper ion homeostasis 1 18 0.5237127
GO:BP GO:0071495 cellular response to endogenous stimulus 1 1097 0.5237127
GO:BP GO:0071692 protein localization to extracellular region 2 265 0.5238080
GO:BP GO:0032212 positive regulation of telomere maintenance via telomerase 1 31 0.5238080
GO:BP GO:0051973 positive regulation of telomerase activity 1 31 0.5238080
GO:BP GO:0048870 cell motility 5 1169 0.5243036
GO:BP GO:0048569 post-embryonic animal organ development 1 15 0.5249783
GO:BP GO:1901970 positive regulation of mitotic sister chromatid separation 1 18 0.5249783
GO:BP GO:0006898 receptor-mediated endocytosis 2 194 0.5250075
GO:BP GO:0007616 long-term memory 1 33 0.5250485
GO:BP GO:0051546 keratinocyte migration 1 15 0.5254791
GO:BP GO:0006112 energy reserve metabolic process 1 72 0.5254791
GO:BP GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 1 46 0.5261730
GO:BP GO:0140112 extracellular vesicle biogenesis 1 20 0.5261730
GO:BP GO:0006400 tRNA modification 3 93 0.5262278
GO:BP GO:0031349 positive regulation of defense response 4 272 0.5262278
GO:BP GO:0070555 response to interleukin-1 1 82 0.5266032
GO:BP GO:1990573 potassium ion import across plasma membrane 1 28 0.5266438
GO:BP GO:0098542 defense response to other organism 1 638 0.5266438
GO:BP GO:0009173 pyrimidine ribonucleoside monophosphate metabolic process 1 13 0.5268133
GO:BP GO:0061157 mRNA destabilization 1 92 0.5277814
GO:BP GO:1905606 regulation of presynapse assembly 1 23 0.5282889
GO:BP GO:0099174 regulation of presynapse organization 1 23 0.5282889
GO:BP GO:1901890 positive regulation of cell junction assembly 1 81 0.5283757
GO:BP GO:0006687 glycosphingolipid metabolic process 1 49 0.5286844
GO:BP GO:0006793 phosphorus metabolic process 37 2118 0.5289958
GO:BP GO:0060135 maternal process involved in female pregnancy 2 40 0.5296234
GO:BP GO:2000678 negative regulation of transcription regulatory region DNA binding 1 17 0.5301497
GO:BP GO:0043524 negative regulation of neuron apoptotic process 2 123 0.5303656
GO:BP GO:1902532 negative regulation of intracellular signal transduction 2 444 0.5303656
GO:BP GO:0010977 negative regulation of neuron projection development 3 117 0.5311660
GO:BP GO:0060252 positive regulation of glial cell proliferation 1 14 0.5311660
GO:BP GO:0014911 positive regulation of smooth muscle cell migration 1 32 0.5314152
GO:BP GO:0032787 monocarboxylic acid metabolic process 1 435 0.5333052
GO:BP GO:1901184 regulation of ERBB signaling pathway 2 59 0.5333709
GO:BP GO:0008033 tRNA processing 4 132 0.5333709
GO:BP GO:0000413 protein peptidyl-prolyl isomerization 1 24 0.5335275
GO:BP GO:0015874 norepinephrine transport 1 10 0.5339050
GO:BP GO:0051402 neuron apoptotic process 3 210 0.5342731
GO:BP GO:0008285 negative regulation of cell population proliferation 10 643 0.5343335
GO:BP GO:2001257 regulation of cation channel activity 1 100 0.5343919
GO:BP GO:0001701 in utero embryonic development 9 338 0.5369739
GO:BP GO:0046887 positive regulation of hormone secretion 1 93 0.5369739
GO:BP GO:0097035 regulation of membrane lipid distribution 1 42 0.5372952
GO:BP GO:0050796 regulation of insulin secretion 5 118 0.5377058
GO:BP GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint 1 18 0.5377901
GO:BP GO:0021549 cerebellum development 1 77 0.5377901
GO:BP GO:0001662 behavioral fear response 1 30 0.5377901
GO:BP GO:1903504 regulation of mitotic spindle checkpoint 1 18 0.5377901
GO:BP GO:0090231 regulation of spindle checkpoint 1 18 0.5377901
GO:BP GO:0048015 phosphatidylinositol-mediated signaling 1 30 0.5377901
GO:BP GO:0050779 RNA destabilization 1 95 0.5377901
GO:BP GO:1905709 negative regulation of membrane permeability 1 19 0.5377901
GO:BP GO:1903432 regulation of TORC1 signaling 1 50 0.5377901
GO:BP GO:0061014 positive regulation of mRNA catabolic process 1 96 0.5377901
GO:BP GO:0006643 membrane lipid metabolic process 1 171 0.5378642
GO:BP GO:0007005 mitochondrion organization 3 500 0.5378642
GO:BP GO:0071684 organism emergence from protective structure 1 22 0.5386399
GO:BP GO:0018107 peptidyl-threonine phosphorylation 2 96 0.5386399
GO:BP GO:0001835 blastocyst hatching 1 22 0.5386399
GO:BP GO:0044057 regulation of system process 2 398 0.5386399
GO:BP GO:0051960 regulation of nervous system development 1 355 0.5386399
GO:BP GO:0035188 hatching 1 22 0.5386399
GO:BP GO:0046824 positive regulation of nucleocytoplasmic transport 2 53 0.5395027
GO:BP GO:2000641 regulation of early endosome to late endosome transport 1 18 0.5406292
GO:BP GO:0007219 Notch signaling pathway 1 145 0.5406292
GO:BP GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 1 48 0.5409555
GO:BP GO:0006611 protein export from nucleus 1 56 0.5411055
GO:BP GO:0006357 regulation of transcription by RNA polymerase II 13 1763 0.5411055
GO:BP GO:0042491 inner ear auditory receptor cell differentiation 1 28 0.5411055
GO:BP GO:0042306 regulation of protein import into nucleus 1 51 0.5411055
GO:BP GO:0045822 negative regulation of heart contraction 1 15 0.5431066
GO:BP GO:0002009 morphogenesis of an epithelium 7 415 0.5432363
GO:BP GO:0008016 regulation of heart contraction 1 171 0.5432363
GO:BP GO:0010628 positive regulation of gene expression 4 796 0.5432363
GO:BP GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 1 42 0.5432363
GO:BP GO:0071548 response to dexamethasone 1 34 0.5432363
GO:BP GO:0035264 multicellular organism growth 2 125 0.5432363
GO:BP GO:0008334 histone mRNA metabolic process 1 20 0.5432363
GO:BP GO:0030182 neuron differentiation 3 1057 0.5432363
GO:BP GO:0002209 behavioral defense response 1 31 0.5432363
GO:BP GO:0006641 triglyceride metabolic process 1 67 0.5432363
GO:BP GO:0051094 positive regulation of developmental process 2 956 0.5432363
GO:BP GO:0032496 response to lipopolysaccharide 3 184 0.5432363
GO:BP GO:0051963 regulation of synapse assembly 1 81 0.5432363
GO:BP GO:0006862 nucleotide transport 1 31 0.5432363
GO:BP GO:1904358 positive regulation of telomere maintenance via telomere lengthening 1 33 0.5432363
GO:BP GO:0045730 respiratory burst 1 22 0.5433063
GO:BP GO:0044248 cellular catabolic process 2 1241 0.5433063
GO:BP GO:0050687 negative regulation of defense response to virus 2 40 0.5435130
GO:BP GO:0070085 glycosylation 2 198 0.5439732
GO:BP GO:0120178 steroid hormone biosynthetic process 1 29 0.5445547
GO:BP GO:0050931 pigment cell differentiation 1 26 0.5445547
GO:BP GO:0043094 cellular metabolic compound salvage 1 25 0.5445948
GO:BP GO:0019318 hexose metabolic process 1 187 0.5447855
GO:BP GO:0035295 tube development 1 822 0.5450650
GO:BP GO:0070306 lens fiber cell differentiation 1 30 0.5454101
GO:BP GO:1900273 positive regulation of long-term synaptic potentiation 1 17 0.5454176
GO:BP GO:0002183 cytoplasmic translational initiation 1 37 0.5462925
GO:BP GO:0051453 regulation of intracellular pH 1 66 0.5464475
GO:BP GO:0070664 negative regulation of leukocyte proliferation 1 51 0.5465158
GO:BP GO:0070242 thymocyte apoptotic process 1 18 0.5465285
GO:BP GO:0031325 positive regulation of cellular metabolic process 35 2519 0.5466989
GO:BP GO:0061245 establishment or maintenance of bipolar cell polarity 1 49 0.5466989
GO:BP GO:0035088 establishment or maintenance of apical/basal cell polarity 1 49 0.5466989
GO:BP GO:0071786 endoplasmic reticulum tubular network organization 1 20 0.5466989
GO:BP GO:0001975 response to amphetamine 1 21 0.5479263
GO:BP GO:0071218 cellular response to misfolded protein 1 23 0.5485209
GO:BP GO:0045582 positive regulation of T cell differentiation 3 74 0.5490502
GO:BP GO:0032642 regulation of chemokine production 1 47 0.5490502
GO:BP GO:0032602 chemokine production 1 47 0.5490502
GO:BP GO:1904064 positive regulation of cation transmembrane transport 1 97 0.5493097
GO:BP GO:0021795 cerebral cortex cell migration 1 37 0.5498360
GO:BP GO:0042181 ketone biosynthetic process 1 38 0.5498360
GO:BP GO:0090102 cochlea development 1 34 0.5498360
GO:BP GO:0120254 olefinic compound metabolic process 3 84 0.5510880
GO:BP GO:0007612 learning 1 114 0.5511274
GO:BP GO:0062125 regulation of mitochondrial gene expression 1 31 0.5529105
GO:BP GO:0007205 protein kinase C-activating G protein-coupled receptor signaling pathway 1 19 0.5529105
GO:BP GO:0019216 regulation of lipid metabolic process 3 251 0.5529105
GO:BP GO:0002092 positive regulation of receptor internalization 1 21 0.5529105
GO:BP GO:0002831 regulation of response to biotic stimulus 7 321 0.5529105
GO:BP GO:1900087 positive regulation of G1/S transition of mitotic cell cycle 1 39 0.5529105
GO:BP GO:1901880 negative regulation of protein depolymerization 1 60 0.5532104
GO:BP GO:1901071 glucosamine-containing compound metabolic process 1 19 0.5532104
GO:BP GO:0045932 negative regulation of muscle contraction 1 17 0.5532104
GO:BP GO:1903523 negative regulation of blood circulation 1 16 0.5532104
GO:BP GO:0061013 regulation of mRNA catabolic process 3 163 0.5539908
GO:BP GO:0007098 centrosome cycle 2 128 0.5540675
GO:BP GO:0046033 AMP metabolic process 1 21 0.5541692
GO:BP GO:0006094 gluconeogenesis 2 70 0.5541751
GO:BP GO:0016447 somatic recombination of immunoglobulin gene segments 1 48 0.5552344
GO:BP GO:0005976 polysaccharide metabolic process 1 81 0.5563617
GO:BP GO:0046856 phosphatidylinositol dephosphorylation 1 26 0.5574157
GO:BP GO:0030641 regulation of cellular pH 1 70 0.5581198
GO:BP GO:0048839 inner ear development 3 129 0.5581198
GO:BP GO:0022037 metencephalon development 1 83 0.5583284
GO:BP GO:0001824 blastocyst development 3 94 0.5583284
GO:BP GO:0051099 positive regulation of binding 2 149 0.5584822
GO:BP GO:0032006 regulation of TOR signaling 2 101 0.5597377
GO:BP GO:0032007 negative regulation of TOR signaling 1 50 0.5597998
GO:BP GO:0045861 negative regulation of proteolysis 4 204 0.5597998
GO:BP GO:0043299 leukocyte degranulation 1 40 0.5605197
GO:BP GO:0003009 skeletal muscle contraction 1 31 0.5605197
GO:BP GO:0033574 response to testosterone 1 30 0.5605197
GO:BP GO:0031175 neuron projection development 5 773 0.5616103
GO:BP GO:0009719 response to endogenous stimulus 1 1260 0.5630175
GO:BP GO:0046823 negative regulation of nucleocytoplasmic transport 1 21 0.5632097
GO:BP GO:1900026 positive regulation of substrate adhesion-dependent cell spreading 1 37 0.5632097
GO:BP GO:0008286 insulin receptor signaling pathway 2 102 0.5636932
GO:BP GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway 1 19 0.5636932
GO:BP GO:0051346 negative regulation of hydrolase activity 4 206 0.5643289
GO:BP GO:0035235 ionotropic glutamate receptor signaling pathway 1 14 0.5650742
GO:BP GO:0033866 nucleoside bisphosphate biosynthetic process 1 50 0.5652668
GO:BP GO:0034030 ribonucleoside bisphosphate biosynthetic process 1 50 0.5652668
GO:BP GO:0034033 purine nucleoside bisphosphate biosynthetic process 1 50 0.5652668
GO:BP GO:0035459 vesicle cargo loading 1 27 0.5655812
GO:BP GO:0010799 regulation of peptidyl-threonine phosphorylation 1 35 0.5657214
GO:BP GO:0048522 positive regulation of cellular process 1 4199 0.5657214
GO:BP GO:0140467 integrated stress response signaling 1 36 0.5657214
GO:BP GO:0071363 cellular response to growth factor stimulus 4 549 0.5657214
GO:BP GO:0002862 negative regulation of inflammatory response to antigenic stimulus 1 17 0.5657937
GO:BP GO:0007276 gamete generation 1 465 0.5660774
GO:BP GO:0072330 monocarboxylic acid biosynthetic process 3 147 0.5660774
GO:BP GO:1904037 positive regulation of epithelial cell apoptotic process 1 26 0.5668636
GO:BP GO:0060337 type I interferon-mediated signaling pathway 1 54 0.5679315
GO:BP GO:0023019 signal transduction involved in regulation of gene expression 1 14 0.5679315
GO:BP GO:0030100 regulation of endocytosis 2 208 0.5684824
GO:BP GO:1902533 positive regulation of intracellular signal transduction 4 707 0.5686242
GO:BP GO:0034976 response to endoplasmic reticulum stress 3 235 0.5687250
GO:BP GO:0016601 Rac protein signal transduction 1 41 0.5688234
GO:BP GO:0019319 hexose biosynthetic process 2 73 0.5689189
GO:BP GO:0010976 positive regulation of neuron projection development 3 133 0.5689864
GO:BP GO:0002237 response to molecule of bacterial origin 3 193 0.5693159
GO:BP GO:2000026 regulation of multicellular organismal development 2 993 0.5693159
GO:BP GO:0045055 regulated exocytosis 2 152 0.5693159
GO:BP GO:0014823 response to activity 1 50 0.5693159
GO:BP GO:0090068 positive regulation of cell cycle process 5 206 0.5693159
GO:BP GO:0010155 regulation of proton transport 1 20 0.5693159
GO:BP GO:0070661 leukocyte proliferation 3 188 0.5693159
GO:BP GO:0014912 negative regulation of smooth muscle cell migration 1 22 0.5693159
GO:BP GO:0061077 chaperone-mediated protein folding 2 63 0.5693159
GO:BP GO:0051788 response to misfolded protein 1 25 0.5693536
GO:BP GO:0071357 cellular response to type I interferon 1 55 0.5695952
GO:BP GO:0051131 chaperone-mediated protein complex assembly 1 21 0.5695952
GO:BP GO:0031348 negative regulation of defense response 2 182 0.5695952
GO:BP GO:0043603 amide metabolic process 17 1004 0.5700434
GO:BP GO:0006739 NADP metabolic process 1 40 0.5700434
GO:BP GO:0051383 kinetochore organization 1 21 0.5700434
GO:BP GO:0051602 response to electrical stimulus 1 29 0.5706374
GO:BP GO:0048699 generation of neurons 3 1119 0.5706374
GO:BP GO:0030262 apoptotic nuclear changes 1 22 0.5706374
GO:BP GO:1901575 organic substance catabolic process 3 1729 0.5711547
GO:BP GO:0048872 homeostasis of number of cells 8 236 0.5711547
GO:BP GO:0051651 maintenance of location in cell 3 177 0.5712343
GO:BP GO:0018210 peptidyl-threonine modification 2 103 0.5718726
GO:BP GO:0071539 protein localization to centrosome 1 31 0.5721542
GO:BP GO:0002685 regulation of leukocyte migration 1 130 0.5721542
GO:BP GO:0048259 regulation of receptor-mediated endocytosis 1 86 0.5724081
GO:BP GO:0032355 response to estradiol 1 79 0.5724110
GO:BP GO:0062207 regulation of pattern recognition receptor signaling pathway 1 94 0.5729189
GO:BP GO:0046037 GMP metabolic process 1 23 0.5729189
GO:BP GO:0051783 regulation of nuclear division 1 115 0.5729918
GO:BP GO:0008206 bile acid metabolic process 1 35 0.5734266
GO:BP GO:0016445 somatic diversification of immunoglobulins 1 53 0.5739014
GO:BP GO:0005996 monosaccharide metabolic process 1 212 0.5739014
GO:BP GO:1900016 negative regulation of cytokine production involved in inflammatory response 1 14 0.5753596
GO:BP GO:0010605 negative regulation of macromolecule metabolic process 37 2131 0.5753596
GO:BP GO:0140527 reciprocal homologous recombination 1 35 0.5755042
GO:BP GO:0007131 reciprocal meiotic recombination 1 35 0.5755042
GO:BP GO:0030516 regulation of axon extension 2 82 0.5755997
GO:BP GO:1901861 regulation of muscle tissue development 1 34 0.5755997
GO:BP GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules 1 10 0.5762808
GO:BP GO:0097484 dendrite extension 1 28 0.5766476
GO:BP GO:0031100 animal organ regeneration 2 47 0.5766476
GO:BP GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 2 56 0.5766476
GO:BP GO:0006816 calcium ion transport 2 275 0.5766476
GO:BP GO:0010950 positive regulation of endopeptidase activity 2 122 0.5766476
GO:BP GO:0097061 dendritic spine organization 2 65 0.5771145
GO:BP GO:0032479 regulation of type I interferon production 2 86 0.5771663
GO:BP GO:0044346 fibroblast apoptotic process 1 23 0.5771663
GO:BP GO:0030217 T cell differentiation 2 189 0.5771663
GO:BP GO:1902894 negative regulation of miRNA transcription 1 22 0.5771663
GO:BP GO:0051450 myoblast proliferation 1 17 0.5771663
GO:BP GO:0032606 type I interferon production 2 86 0.5771663
GO:BP GO:0010951 negative regulation of endopeptidase activity 2 93 0.5771663
GO:BP GO:0014910 regulation of smooth muscle cell migration 2 57 0.5771663
GO:BP GO:0045648 positive regulation of erythrocyte differentiation 1 26 0.5771663
GO:BP GO:0046697 decidualization 1 19 0.5771663
GO:BP GO:0014856 skeletal muscle cell proliferation 1 17 0.5771663
GO:BP GO:0090200 positive regulation of release of cytochrome c from mitochondria 1 21 0.5771663
GO:BP GO:1905508 protein localization to microtubule organizing center 1 32 0.5785158
GO:BP GO:0072080 nephron tubule development 1 74 0.5785158
GO:BP GO:0043507 positive regulation of JUN kinase activity 1 35 0.5785158
GO:BP GO:0050770 regulation of axonogenesis 3 139 0.5786345
GO:BP GO:0060047 heart contraction 1 202 0.5790548
GO:BP GO:0001676 long-chain fatty acid metabolic process 1 63 0.5790548
GO:BP GO:0009205 purine ribonucleoside triphosphate metabolic process 2 135 0.5790548
GO:BP GO:0039694 viral RNA genome replication 1 27 0.5790548
GO:BP GO:0045292 mRNA cis splicing, via spliceosome 1 26 0.5795201
GO:BP GO:0050678 regulation of epithelial cell proliferation 3 268 0.5800112
GO:BP GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 1 113 0.5801094
GO:BP GO:0006909 phagocytosis 1 144 0.5801094
GO:BP GO:0006885 regulation of pH 1 74 0.5807278
GO:BP GO:0035315 hair cell differentiation 1 33 0.5811568
GO:BP GO:0009048 dosage compensation by inactivation of X chromosome 1 28 0.5811568
GO:BP GO:0060997 dendritic spine morphogenesis 1 47 0.5811568
GO:BP GO:1990830 cellular response to leukemia inhibitory factor 3 86 0.5814313
GO:BP GO:0097107 postsynaptic density assembly 1 15 0.5828590
GO:BP GO:0034767 positive regulation of monoatomic ion transmembrane transport 1 112 0.5828590
GO:BP GO:0006813 potassium ion transport 1 146 0.5840330
GO:BP GO:0048666 neuron development 6 872 0.5849013
GO:BP GO:0043242 negative regulation of protein-containing complex disassembly 1 68 0.5849798
GO:BP GO:0006921 cellular component disassembly involved in execution phase of apoptosis 1 24 0.5852605
GO:BP GO:0030177 positive regulation of Wnt signaling pathway 2 119 0.5863303
GO:BP GO:0070536 protein K63-linked deubiquitination 1 33 0.5865803
GO:BP GO:0014070 response to organic cyclic compound 12 632 0.5868558
GO:BP GO:0034340 response to type I interferon 1 60 0.5868558
GO:BP GO:0002221 pattern recognition receptor signaling pathway 2 142 0.5871059
GO:BP GO:1990823 response to leukemia inhibitory factor 3 87 0.5872580
GO:BP GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 1 55 0.5877846
GO:BP GO:0045662 negative regulation of myoblast differentiation 1 20 0.5877846
GO:BP GO:0016444 somatic cell DNA recombination 1 55 0.5877846
GO:BP GO:0051707 response to other organism 1 846 0.5878378
GO:BP GO:0043207 response to external biotic stimulus 1 846 0.5881288
GO:BP GO:0009129 pyrimidine nucleoside monophosphate metabolic process 1 18 0.5881288
GO:BP GO:0070848 response to growth factor 4 571 0.5881288
GO:BP GO:0050730 regulation of peptidyl-tyrosine phosphorylation 1 160 0.5881288
GO:BP GO:1901223 negative regulation of non-canonical NF-kappaB signal transduction 1 22 0.5884563
GO:BP GO:0016051 carbohydrate biosynthetic process 2 160 0.5888140
GO:BP GO:0090630 activation of GTPase activity 2 93 0.5888140
GO:BP GO:0051147 regulation of muscle cell differentiation 1 118 0.5892985
GO:BP GO:0006783 heme biosynthetic process 1 29 0.5894508
GO:BP GO:1900542 regulation of purine nucleotide metabolic process 1 38 0.5905933
GO:BP GO:0050773 regulation of dendrite development 2 82 0.5905933
GO:BP GO:0060998 regulation of dendritic spine development 1 51 0.5905933
GO:BP GO:0009967 positive regulation of signal transduction 17 1115 0.5910345
GO:BP GO:2000772 regulation of cellular senescence 1 37 0.5916812
GO:BP GO:0034765 regulation of monoatomic ion transmembrane transport 2 296 0.5924757
GO:BP GO:0003015 heart process 1 213 0.5926545
GO:BP GO:0006629 lipid metabolic process 19 989 0.5926755
GO:BP GO:0006775 fat-soluble vitamin metabolic process 1 21 0.5932991
GO:BP GO:0002706 regulation of lymphocyte mediated immunity 1 90 0.5932991
GO:BP GO:0048518 positive regulation of biological process 1 4568 0.5934630
GO:BP GO:0019082 viral protein processing 1 31 0.5936443
GO:BP GO:0002703 regulation of leukocyte mediated immunity 2 123 0.5936508
GO:BP GO:0009607 response to biotic stimulus 1 874 0.5945637
GO:BP GO:0035967 cellular response to topologically incorrect protein 3 103 0.5946328
GO:BP GO:0042462 eye photoreceptor cell development 1 19 0.5950329
GO:BP GO:0071385 cellular response to glucocorticoid stimulus 1 37 0.5952850
GO:BP GO:0000902 cell morphogenesis 2 739 0.5952850
GO:BP GO:1903522 regulation of blood circulation 1 197 0.5953551
GO:BP GO:0045070 positive regulation of viral genome replication 1 27 0.5953551
GO:BP GO:0006140 regulation of nucleotide metabolic process 1 38 0.5955585
GO:BP GO:0071470 cellular response to osmotic stress 1 41 0.5955585
GO:BP GO:0034308 primary alcohol metabolic process 2 60 0.5959043
GO:BP GO:0032148 activation of protein kinase B activity 1 24 0.5959043
GO:BP GO:0009199 ribonucleoside triphosphate metabolic process 2 142 0.5959043
GO:BP GO:0009144 purine nucleoside triphosphate metabolic process 2 142 0.5959043
GO:BP GO:0034446 substrate adhesion-dependent cell spreading 2 90 0.5959043
GO:BP GO:0007549 dosage compensation 1 30 0.5959334
GO:BP GO:0051235 maintenance of location 4 263 0.5965333
GO:BP GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 1 42 0.5965333
GO:BP GO:0019725 cellular homeostasis 5 583 0.5965333
GO:BP GO:0048609 multicellular organismal reproductive process 1 538 0.5969624
GO:BP GO:0033617 mitochondrial cytochrome c oxidase assembly 1 25 0.5974052
GO:BP GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 1 23 0.5979013
GO:BP GO:0046822 regulation of nucleocytoplasmic transport 3 98 0.5979013
GO:BP GO:0033628 regulation of cell adhesion mediated by integrin 1 36 0.5979013
GO:BP GO:0008347 glial cell migration 1 48 0.5982773
GO:BP GO:0031122 cytoplasmic microtubule organization 1 58 0.5982773
GO:BP GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1 104 0.5993568
GO:BP GO:0060071 Wnt signaling pathway, planar cell polarity pathway 1 51 0.5994635
GO:BP GO:0019722 calcium-mediated signaling 1 118 0.6013004
GO:BP GO:0008643 carbohydrate transport 4 115 0.6018144
GO:BP GO:0035825 homologous recombination 1 42 0.6021250
GO:BP GO:0042147 retrograde transport, endosome to Golgi 3 90 0.6021250
GO:BP GO:0002275 myeloid cell activation involved in immune response 1 47 0.6021250
GO:BP GO:0046578 regulation of Ras protein signal transduction 1 156 0.6021250
GO:BP GO:0006402 mRNA catabolic process 7 218 0.6021250
GO:BP GO:0042177 negative regulation of protein catabolic process 1 100 0.6021250
GO:BP GO:0031110 regulation of microtubule polymerization or depolymerization 1 81 0.6021250
GO:BP GO:1901879 regulation of protein depolymerization 1 74 0.6021250
GO:BP GO:0035065 regulation of histone acetylation 1 29 0.6021667
GO:BP GO:0046364 monosaccharide biosynthetic process 2 82 0.6025776
GO:BP GO:0016242 negative regulation of macroautophagy 1 31 0.6025776
GO:BP GO:0006911 phagocytosis, engulfment 1 30 0.6031108
GO:BP GO:0071310 cellular response to organic substance 1 1389 0.6037091
GO:BP GO:0086064 cell communication by electrical coupling involved in cardiac conduction 1 26 0.6045998
GO:BP GO:0033137 negative regulation of peptidyl-serine phosphorylation 1 25 0.6045998
GO:BP GO:0018230 peptidyl-L-cysteine S-palmitoylation 1 21 0.6045998
GO:BP GO:1901028 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway 1 25 0.6045998
GO:BP GO:0018231 peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine 1 21 0.6045998
GO:BP GO:0007423 sensory organ development 1 395 0.6046531
GO:BP GO:0019079 viral genome replication 3 104 0.6047933
GO:BP GO:0045621 positive regulation of lymphocyte differentiation 1 86 0.6057990
GO:BP GO:0023061 signal release 2 328 0.6066409
GO:BP GO:0061180 mammary gland epithelium development 1 56 0.6070658
GO:BP GO:1903313 positive regulation of mRNA metabolic process 1 121 0.6074534
GO:BP GO:0002200 somatic diversification of immune receptors 1 61 0.6074534
GO:BP GO:0050777 negative regulation of immune response 1 118 0.6074534
GO:BP GO:0002683 negative regulation of immune system process 2 304 0.6084436
GO:BP GO:0010952 positive regulation of peptidase activity 2 135 0.6104553
GO:BP GO:0009220 pyrimidine ribonucleotide biosynthetic process 1 19 0.6104553
GO:BP GO:0045943 positive regulation of transcription by RNA polymerase I 1 34 0.6104553
GO:BP GO:0003018 vascular process in circulatory system 1 198 0.6104553
GO:BP GO:0019915 lipid storage 1 68 0.6108085
GO:BP GO:1904659 glucose transmembrane transport 3 84 0.6108085
GO:BP GO:0030097 hemopoiesis 1 650 0.6108085
GO:BP GO:0006110 regulation of glycolytic process 1 43 0.6108085
GO:BP GO:0022029 telencephalon cell migration 1 44 0.6113814
GO:BP GO:0007399 nervous system development 3 1882 0.6113814
GO:BP GO:0032504 multicellular organism reproduction 1 558 0.6116303
GO:BP GO:0032370 positive regulation of lipid transport 1 57 0.6117484
GO:BP GO:0009395 phospholipid catabolic process 1 37 0.6127147
GO:BP GO:0071875 adrenergic receptor signaling pathway 1 24 0.6128242
GO:BP GO:0009394 2’-deoxyribonucleotide metabolic process 1 34 0.6130047
GO:BP GO:0045595 regulation of cell differentiation 2 1118 0.6132005
GO:BP GO:0032273 positive regulation of protein polymerization 1 75 0.6145552
GO:BP GO:0050804 modulation of chemical synaptic transmission 2 343 0.6145552
GO:BP GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 1 23 0.6150980
GO:BP GO:0099177 regulation of trans-synaptic signaling 2 344 0.6155326
GO:BP GO:0035176 social behavior 1 34 0.6160080
GO:BP GO:0048814 regulation of dendrite morphogenesis 1 53 0.6160080
GO:BP GO:0098739 import across plasma membrane 1 130 0.6160535
GO:BP GO:1901617 organic hydroxy compound biosynthetic process 3 174 0.6162023
GO:BP GO:0014909 smooth muscle cell migration 2 64 0.6171973
GO:BP GO:0097553 calcium ion transmembrane import into cytosol 1 125 0.6176615
GO:BP GO:0002758 innate immune response-activating signaling pathway 2 149 0.6180237
GO:BP GO:1903829 positive regulation of protein localization 2 392 0.6193668
GO:BP GO:0099054 presynapse assembly 1 37 0.6193668
GO:BP GO:0010558 negative regulation of macromolecule biosynthetic process 1 1668 0.6193668
GO:BP GO:0006897 endocytosis 4 525 0.6193668
GO:BP GO:0019692 deoxyribose phosphate metabolic process 1 35 0.6193668
GO:BP GO:0090175 regulation of establishment of planar polarity 1 54 0.6193668
GO:BP GO:0009161 ribonucleoside monophosphate metabolic process 2 51 0.6193668
GO:BP GO:0046324 regulation of glucose import 1 42 0.6193668
GO:BP GO:0009262 deoxyribonucleotide metabolic process 1 35 0.6193668
GO:BP GO:0002819 regulation of adaptive immune response 1 113 0.6196196
GO:BP GO:0090276 regulation of peptide hormone secretion 1 134 0.6196196
GO:BP GO:0048066 developmental pigmentation 1 36 0.6203854
GO:BP GO:0043583 ear development 3 150 0.6205069
GO:BP GO:0006839 mitochondrial transport 1 172 0.6223527
GO:BP GO:0043933 protein-containing complex organization 12 1974 0.6224080
GO:BP GO:0030073 insulin secretion 1 143 0.6224080
GO:BP GO:0051085 chaperone cofactor-dependent protein refolding 1 30 0.6224080
GO:BP GO:0050886 endocrine process 1 56 0.6224080
GO:BP GO:0003006 developmental process involved in reproduction 1 603 0.6224080
GO:BP GO:0051241 negative regulation of multicellular organismal process 3 743 0.6233008
GO:BP GO:0106027 neuron projection organization 2 74 0.6233530
GO:BP GO:0016482 cytosolic transport 5 167 0.6235161
GO:BP GO:0050881 musculoskeletal movement 1 41 0.6235161
GO:BP GO:0021885 forebrain cell migration 1 46 0.6235161
GO:BP GO:0043408 regulation of MAPK cascade 2 473 0.6237285
GO:BP GO:0008645 hexose transmembrane transport 3 87 0.6238782
GO:BP GO:0072009 nephron epithelium development 1 87 0.6242978
GO:BP GO:0031327 negative regulation of cellular biosynthetic process 1 1707 0.6243296
GO:BP GO:0051703 biological process involved in intraspecies interaction between organisms 1 34 0.6253904
GO:BP GO:0009636 response to toxic substance 3 158 0.6254926
GO:BP GO:1901224 positive regulation of non-canonical NF-kappaB signal transduction 1 42 0.6256741
GO:BP GO:0009890 negative regulation of biosynthetic process 1 1720 0.6259743
GO:BP GO:0006952 defense response 1 970 0.6284731
GO:BP GO:0050879 multicellular organismal movement 1 41 0.6290653
GO:BP GO:0043467 regulation of generation of precursor metabolites and energy 2 119 0.6306927
GO:BP GO:0010507 negative regulation of autophagy 2 75 0.6306927
GO:BP GO:0062012 regulation of small molecule metabolic process 1 248 0.6306927
GO:BP GO:1902808 positive regulation of cell cycle G1/S phase transition 1 49 0.6315015
GO:BP GO:0007155 cell adhesion 1 996 0.6315015
GO:BP GO:0007626 locomotory behavior 1 139 0.6330299
GO:BP GO:0019226 transmission of nerve impulse 1 35 0.6332229
GO:BP GO:0140888 interferon-mediated signaling pathway 1 69 0.6359747
GO:BP GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1 27 0.6361775
GO:BP GO:0042098 T cell proliferation 1 120 0.6364082
GO:BP GO:0050896 response to stimulus 5 5725 0.6383857
GO:BP GO:0048638 regulation of developmental growth 4 255 0.6383857
GO:BP GO:0031960 response to corticosteroid 2 93 0.6383857
GO:BP GO:0018108 peptidyl-tyrosine phosphorylation 1 195 0.6390000
GO:BP GO:0045920 negative regulation of exocytosis 1 24 0.6390074
GO:BP GO:0010737 protein kinase A signaling 1 23 0.6395854
GO:BP GO:0009141 nucleoside triphosphate metabolic process 2 158 0.6395854
GO:BP GO:0015749 monosaccharide transmembrane transport 3 88 0.6403215
GO:BP GO:0018212 peptidyl-tyrosine modification 1 197 0.6408100
GO:BP GO:0002444 myeloid leukocyte mediated immunity 1 58 0.6408100
GO:BP GO:0009112 nucleobase metabolic process 1 28 0.6416555
GO:BP GO:0003008 system process 1 1193 0.6433882
GO:BP GO:0030902 hindbrain development 1 114 0.6439147
GO:BP GO:0022604 regulation of cell morphogenesis 4 207 0.6441165
GO:BP GO:0099172 presynapse organization 1 40 0.6441165
GO:BP GO:0048732 gland development 1 319 0.6448069
GO:BP GO:0018208 peptidyl-proline modification 1 39 0.6448664
GO:BP GO:0006260 DNA replication 1 256 0.6448664
GO:BP GO:0045684 positive regulation of epidermis development 1 20 0.6448664
GO:BP GO:0018105 peptidyl-serine phosphorylation 4 242 0.6451620
GO:BP GO:0045471 response to ethanol 3 72 0.6452280
GO:BP GO:0035510 DNA dealkylation 1 28 0.6452280
GO:BP GO:0019953 sexual reproduction 1 633 0.6456363
GO:BP GO:0030968 endoplasmic reticulum unfolded protein response 2 70 0.6456363
GO:BP GO:0033077 T cell differentiation in thymus 1 57 0.6461140
GO:BP GO:1990806 ligand-gated ion channel signaling pathway 1 20 0.6461140
GO:BP GO:0022008 neurogenesis 3 1295 0.6461140
GO:BP GO:0008360 regulation of cell shape 2 115 0.6461140
GO:BP GO:0042509 regulation of tyrosine phosphorylation of STAT protein 1 34 0.6463932
GO:BP GO:0008535 respiratory chain complex IV assembly 1 29 0.6468806
GO:BP GO:0042446 hormone biosynthetic process 1 39 0.6469028
GO:BP GO:0030517 negative regulation of axon extension 1 41 0.6469028
GO:BP GO:0043331 response to dsRNA 1 33 0.6469028
GO:BP GO:0015844 monoamine transport 2 48 0.6472559
GO:BP GO:1903018 regulation of glycoprotein metabolic process 1 35 0.6484291
GO:BP GO:0002312 B cell activation involved in immune response 1 58 0.6493289
GO:BP GO:0001756 somitogenesis 1 48 0.6500764
GO:BP GO:0061512 protein localization to cilium 1 62 0.6501876
GO:BP GO:0099024 plasma membrane invagination 1 39 0.6505574
GO:BP GO:0051223 regulation of protein transport 2 403 0.6507910
GO:BP GO:0009653 anatomical structure morphogenesis 3 1952 0.6513855
GO:BP GO:0060255 regulation of macromolecule metabolic process 103 4597 0.6513855
GO:BP GO:0048523 negative regulation of cellular process 30 3772 0.6521163
GO:BP GO:0043523 regulation of neuron apoptotic process 5 171 0.6523429
GO:BP GO:0070613 regulation of protein processing 2 48 0.6523811
GO:BP GO:0009612 response to mechanical stimulus 1 155 0.6523811
GO:BP GO:0062013 positive regulation of small molecule metabolic process 2 107 0.6530812
GO:BP GO:0007610 behavior 3 438 0.6535841
GO:BP GO:0030072 peptide hormone secretion 6 168 0.6538608
GO:BP GO:2000377 regulation of reactive oxygen species metabolic process 1 107 0.6538970
GO:BP GO:2000463 positive regulation of excitatory postsynaptic potential 1 29 0.6551853
GO:BP GO:0006874 intracellular calcium ion homeostasis 1 208 0.6558027
GO:BP GO:0009225 nucleotide-sugar metabolic process 1 36 0.6559509
GO:BP GO:0071241 cellular response to inorganic substance 3 165 0.6566020
GO:BP GO:0044255 cellular lipid metabolic process 1 736 0.6566020
GO:BP GO:0050680 negative regulation of epithelial cell proliferation 1 107 0.6566020
GO:BP GO:0014075 response to amine 1 34 0.6566020
GO:BP GO:0009895 negative regulation of catabolic process 9 287 0.6566020
GO:BP GO:0071168 protein localization to chromatin 1 42 0.6566020
GO:BP GO:0030855 epithelial cell differentiation 1 437 0.6566020
GO:BP GO:0007260 tyrosine phosphorylation of STAT protein 1 36 0.6569179
GO:BP GO:0042273 ribosomal large subunit biogenesis 1 70 0.6575399
GO:BP GO:1901564 organonitrogen compound metabolic process 17 4921 0.6575399
GO:BP GO:0010817 regulation of hormone levels 2 336 0.6576120
GO:BP GO:0098698 postsynaptic specialization assembly 1 22 0.6576616
GO:BP GO:0120162 positive regulation of cold-induced thermogenesis 1 72 0.6576616
GO:BP GO:0009892 negative regulation of metabolic process 38 2297 0.6576616
GO:BP GO:0043484 regulation of RNA splicing 3 163 0.6576616
GO:BP GO:0006955 immune response 1 915 0.6584029
GO:BP GO:0046839 phospholipid dephosphorylation 1 36 0.6586461
GO:BP GO:1900024 regulation of substrate adhesion-dependent cell spreading 1 54 0.6586697
GO:BP GO:0038093 Fc receptor signaling pathway 1 36 0.6589377
GO:BP GO:0034764 positive regulation of transmembrane transport 1 155 0.6612739
GO:BP GO:0090407 organophosphate biosynthetic process 2 506 0.6626571
GO:BP GO:0006513 protein monoubiquitination 1 71 0.6640820
GO:BP GO:0062014 negative regulation of small molecule metabolic process 1 75 0.6643344
GO:BP GO:0007420 brain development 1 545 0.6649265
GO:BP GO:0023051 regulation of signaling 2 2559 0.6649265
GO:BP GO:0050776 regulation of immune response 6 513 0.6649265
GO:BP GO:1903146 regulation of autophagy of mitochondrion 1 37 0.6655036
GO:BP GO:1902914 regulation of protein polyubiquitination 1 25 0.6658365
GO:BP GO:0051084 ‘de novo’ post-translational protein folding 1 35 0.6658365
GO:BP GO:0042572 retinol metabolic process 1 23 0.6658365
GO:BP GO:0010646 regulation of cell communication 2 2566 0.6658803
GO:BP GO:1900076 regulation of cellular response to insulin stimulus 1 55 0.6666209
GO:BP GO:0008593 regulation of Notch signaling pathway 2 78 0.6681850
GO:BP GO:2000628 regulation of miRNA metabolic process 2 69 0.6682563
GO:BP GO:0048468 cell development 3 1947 0.6685503
GO:BP GO:0032965 regulation of collagen biosynthetic process 1 27 0.6695841
GO:BP GO:0001893 maternal placenta development 1 28 0.6695841
GO:BP GO:0048645 animal organ formation 1 50 0.6702908
GO:BP GO:0043488 regulation of mRNA stability 1 149 0.6711915
GO:BP GO:0033993 response to lipid 8 593 0.6713135
GO:BP GO:0070201 regulation of establishment of protein localization 2 427 0.6718782
GO:BP GO:0090075 relaxation of muscle 1 27 0.6733827
GO:BP GO:0010837 regulation of keratinocyte proliferation 1 33 0.6733827
GO:BP GO:1903318 negative regulation of protein maturation 1 20 0.6733829
GO:BP GO:0010955 negative regulation of protein processing 1 20 0.6733829
GO:BP GO:0031324 negative regulation of cellular metabolic process 1 2069 0.6733829
GO:BP GO:0009798 axis specification 1 61 0.6736766
GO:BP GO:0023056 positive regulation of signaling 9 1251 0.6744739
GO:BP GO:0002250 adaptive immune response 1 226 0.6744739
GO:BP GO:0002376 immune system process 2 1483 0.6751574
GO:BP GO:0050794 regulation of cellular process 8 7639 0.6751581
GO:BP GO:0044272 sulfur compound biosynthetic process 1 123 0.6754532
GO:BP GO:0015909 long-chain fatty acid transport 1 37 0.6754532
GO:BP GO:0065003 protein-containing complex assembly 1 1331 0.6756717
GO:BP GO:0033157 regulation of intracellular protein transport 2 198 0.6756717
GO:BP GO:0033146 regulation of intracellular estrogen receptor signaling pathway 1 28 0.6756717
GO:BP GO:0055074 calcium ion homeostasis 1 221 0.6756920
GO:BP GO:0042461 photoreceptor cell development 1 30 0.6763730
GO:BP GO:0032103 positive regulation of response to external stimulus 3 359 0.6767468
GO:BP GO:1903317 regulation of protein maturation 2 51 0.6768110
GO:BP GO:0010762 regulation of fibroblast migration 1 37 0.6768110
GO:BP GO:0046320 regulation of fatty acid oxidation 1 30 0.6768110
GO:BP GO:0031667 response to nutrient levels 6 355 0.6768715
GO:BP GO:0060411 cardiac septum morphogenesis 1 67 0.6772553
GO:BP GO:1905954 positive regulation of lipid localization 1 74 0.6772553
GO:BP GO:1903305 regulation of regulated secretory pathway 1 86 0.6772553
GO:BP GO:0006304 DNA modification 2 86 0.6772957
GO:BP GO:0042088 T-helper 1 type immune response 1 27 0.6772957
GO:BP GO:0002861 regulation of inflammatory response to antigenic stimulus 1 25 0.6780456
GO:BP GO:0048583 regulation of response to stimulus 21 2876 0.6788277
GO:BP GO:0051049 regulation of transport 1 1266 0.6788998
GO:BP GO:0050673 epithelial cell proliferation 3 318 0.6788998
GO:BP GO:0018209 peptidyl-serine modification 4 254 0.6790133
GO:BP GO:0014808 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 1 29 0.6790361
GO:BP GO:0045666 positive regulation of neuron differentiation 2 63 0.6790361
GO:BP GO:0045646 regulation of erythrocyte differentiation 1 38 0.6790361
GO:BP GO:0010644 cell communication by electrical coupling 1 31 0.6790361
GO:BP GO:0002262 myeloid cell homeostasis 4 142 0.6790361
GO:BP GO:0060688 regulation of morphogenesis of a branching structure 1 37 0.6790361
GO:BP GO:0006936 muscle contraction 1 266 0.6790361
GO:BP GO:0050830 defense response to Gram-positive bacterium 1 37 0.6797409
GO:BP GO:0010324 membrane invagination 1 46 0.6799653
GO:BP GO:0051716 cellular response to stimulus 4 4930 0.6799653
GO:BP GO:0048593 camera-type eye morphogenesis 3 92 0.6799653
GO:BP GO:0051259 protein complex oligomerization 4 190 0.6804755
GO:BP GO:0051445 regulation of meiotic cell cycle 1 45 0.6808097
GO:BP GO:0007405 neuroblast proliferation 1 56 0.6808097
GO:BP GO:0060322 head development 1 587 0.6808097
GO:BP GO:0097305 response to alcohol 3 160 0.6812429
GO:BP GO:1905898 positive regulation of response to endoplasmic reticulum stress 1 34 0.6814050
GO:BP GO:0000380 alternative mRNA splicing, via spliceosome 1 63 0.6814050
GO:BP GO:1901222 regulation of non-canonical NF-kappaB signal transduction 2 67 0.6814050
GO:BP GO:0030001 metal ion transport 3 569 0.6815545
GO:BP GO:0000165 MAPK cascade 2 553 0.6828178
GO:BP GO:0009101 glycoprotein biosynthetic process 3 252 0.6828178
GO:BP GO:0006694 steroid biosynthetic process 2 124 0.6829807
GO:BP GO:0048705 skeletal system morphogenesis 3 155 0.6832299
GO:BP GO:0046942 carboxylic acid transport 1 213 0.6841326
GO:BP GO:0015849 organic acid transport 1 214 0.6852098
GO:BP GO:0014812 muscle cell migration 2 75 0.6861114
GO:BP GO:0072073 kidney epithelium development 1 113 0.6862376
GO:BP GO:0016052 carbohydrate catabolic process 1 125 0.6867084
GO:BP GO:1903514 release of sequestered calcium ion into cytosol by endoplasmic reticulum 1 29 0.6867084
GO:BP GO:0032868 response to insulin 2 211 0.6874027
GO:BP GO:0035567 non-canonical Wnt signaling pathway 1 67 0.6875450
GO:BP GO:0001889 liver development 3 111 0.6879603
GO:BP GO:0060251 regulation of glial cell proliferation 1 26 0.6886742
GO:BP GO:0006040 amino sugar metabolic process 1 34 0.6886742
GO:BP GO:0043487 regulation of RNA stability 1 161 0.6886742
GO:BP GO:0032640 tumor necrosis factor production 1 90 0.6886742
GO:BP GO:0032680 regulation of tumor necrosis factor production 1 90 0.6886742
GO:BP GO:0006301 postreplication repair 1 33 0.6890802
GO:BP GO:0070227 lymphocyte apoptotic process 2 58 0.6890802
GO:BP GO:0009167 purine ribonucleoside monophosphate metabolic process 1 36 0.6896390
GO:BP GO:0043123 positive regulation of canonical NF-kappaB signal transduction 2 154 0.6900333
GO:BP GO:0034762 regulation of transmembrane transport 2 392 0.6902875
GO:BP GO:0048584 positive regulation of response to stimulus 11 1556 0.6904201
GO:BP GO:0061515 myeloid cell development 1 58 0.6904201
GO:BP GO:0018345 protein palmitoylation 1 30 0.6923819
GO:BP GO:0046323 glucose import 1 55 0.6926325
GO:BP GO:0006458 ‘de novo’ protein folding 1 39 0.6930381
GO:BP GO:0006305 DNA alkylation 1 41 0.6931038
GO:BP GO:0007416 synapse assembly 1 152 0.6931038
GO:BP GO:0042168 heme metabolic process 1 39 0.6931038
GO:BP GO:1902275 regulation of chromatin organization 1 45 0.6931038
GO:BP GO:1900181 negative regulation of protein localization to nucleus 1 30 0.6931038
GO:BP GO:0045580 regulation of T cell differentiation 1 110 0.6931038
GO:BP GO:0006306 DNA methylation 1 41 0.6931038
GO:BP GO:0006308 DNA catabolic process 1 25 0.6939877
GO:BP GO:0072006 nephron development 1 118 0.6943920
GO:BP GO:0051260 protein homooligomerization 3 138 0.6946174
GO:BP GO:0050679 positive regulation of epithelial cell proliferation 1 152 0.6946174
GO:BP GO:0018193 peptidyl-amino acid modification 5 866 0.6946174
GO:BP GO:0032412 regulation of monoatomic ion transmembrane transporter activity 1 189 0.6946174
GO:BP GO:0002377 immunoglobulin production 1 70 0.6947946
GO:BP GO:0010827 regulation of glucose transmembrane transport 1 56 0.6949302
GO:BP GO:0045923 positive regulation of fatty acid metabolic process 1 27 0.6949302
GO:BP GO:0045860 positive regulation of protein kinase activity 1 258 0.6949302
GO:BP GO:0050727 regulation of inflammatory response 2 215 0.6949302
GO:BP GO:0071706 tumor necrosis factor superfamily cytokine production 1 93 0.6949302
GO:BP GO:2000785 regulation of autophagosome assembly 1 43 0.6949302
GO:BP GO:0006356 regulation of transcription by RNA polymerase I 1 47 0.6949302
GO:BP GO:1903214 regulation of protein targeting to mitochondrion 1 40 0.6949302
GO:BP GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 1 93 0.6949302
GO:BP GO:0006221 pyrimidine nucleotide biosynthetic process 1 28 0.6950792
GO:BP GO:0009888 tissue development 4 1423 0.6950792
GO:BP GO:0009218 pyrimidine ribonucleotide metabolic process 1 26 0.6950792
GO:BP GO:1903708 positive regulation of hemopoiesis 1 118 0.6959312
GO:BP GO:1902107 positive regulation of leukocyte differentiation 1 118 0.6959312
GO:BP GO:0048536 spleen development 1 29 0.6962326
GO:BP GO:0050878 regulation of body fluid levels 1 237 0.6964534
GO:BP GO:1902369 negative regulation of RNA catabolic process 2 71 0.6964534
GO:BP GO:0008344 adult locomotory behavior 1 60 0.6982021
GO:BP GO:1904861 excitatory synapse assembly 1 26 0.6982021
GO:BP GO:0045444 fat cell differentiation 5 186 0.7004425
GO:BP GO:0010033 response to organic substance 1 1941 0.7007485
GO:BP GO:0051258 protein polymerization 2 237 0.7015393
GO:BP GO:0046513 ceramide biosynthetic process 1 53 0.7020855
GO:BP GO:0035329 hippo signaling 1 40 0.7020855
GO:BP GO:0043403 skeletal muscle tissue regeneration 1 30 0.7021800
GO:BP GO:0010712 regulation of collagen metabolic process 1 31 0.7021800
GO:BP GO:0040007 growth 16 737 0.7033590
GO:BP GO:0006270 DNA replication initiation 1 35 0.7035746
GO:BP GO:1901888 regulation of cell junction assembly 1 165 0.7042063
GO:BP GO:0072698 protein localization to microtubule cytoskeleton 1 51 0.7046992
GO:BP GO:0022898 regulation of transmembrane transporter activity 1 200 0.7069685
GO:BP GO:0006275 regulation of DNA replication 3 116 0.7069685
GO:BP GO:0007173 epidermal growth factor receptor signaling pathway 2 89 0.7069685
GO:BP GO:0016525 negative regulation of angiogenesis 1 71 0.7071448
GO:BP GO:1900225 regulation of NLRP3 inflammasome complex assembly 1 26 0.7073112
GO:BP GO:0010629 negative regulation of gene expression 8 823 0.7086255
GO:BP GO:0035633 maintenance of blood-brain barrier 1 29 0.7093136
GO:BP GO:0051050 positive regulation of transport 3 665 0.7098805
GO:BP GO:2000181 negative regulation of blood vessel morphogenesis 1 72 0.7103904
GO:BP GO:0061053 somite development 1 62 0.7121463
GO:BP GO:0006953 acute-phase response 1 19 0.7127631
GO:BP GO:0044283 small molecule biosynthetic process 6 433 0.7127631
GO:BP GO:0140747 regulation of ncRNA transcription 2 79 0.7135883
GO:BP GO:1901343 negative regulation of vasculature development 1 72 0.7135883
GO:BP GO:0034620 cellular response to unfolded protein 2 83 0.7137517
GO:BP GO:0006139 nucleobase-containing compound metabolic process 2 4487 0.7139602
GO:BP GO:0046777 protein autophosphorylation 1 183 0.7175633
GO:BP GO:0065008 regulation of biological quality 1 2083 0.7194153
GO:BP GO:0000910 cytokinesis 3 164 0.7194153
GO:BP GO:0030098 lymphocyte differentiation 2 262 0.7195500
GO:BP GO:0009991 response to extracellular stimulus 6 379 0.7197770
GO:BP GO:0006401 RNA catabolic process 4 261 0.7199686
GO:BP GO:0019932 second-messenger-mediated signaling 1 182 0.7210202
GO:BP GO:0042092 type 2 immune response 1 19 0.7210202
GO:BP GO:0050900 leukocyte migration 1 207 0.7210202
GO:BP GO:0010468 regulation of gene expression 82 3590 0.7210611
GO:BP GO:2000573 positive regulation of DNA biosynthetic process 1 66 0.7235654
GO:BP GO:0017004 cytochrome complex assembly 1 38 0.7243831
GO:BP GO:0030324 lung development 1 144 0.7253746
GO:BP GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 1 35 0.7261386
GO:BP GO:0051093 negative regulation of developmental process 1 652 0.7261386
GO:BP GO:0044546 NLRP3 inflammasome complex assembly 1 26 0.7261386
GO:BP GO:0032409 regulation of transporter activity 1 212 0.7265792
GO:BP GO:0032480 negative regulation of type I interferon production 1 30 0.7267441
GO:BP GO:0060041 retina development in camera-type eye 3 109 0.7267441
GO:BP GO:0007009 plasma membrane organization 2 114 0.7267441
GO:BP GO:0019362 pyridine nucleotide metabolic process 1 64 0.7280169
GO:BP GO:0046496 nicotinamide nucleotide metabolic process 1 64 0.7280169
GO:BP GO:0044380 protein localization to cytoskeleton 1 54 0.7280480
GO:BP GO:0042119 neutrophil activation 1 16 0.7281148
GO:BP GO:0098586 cellular response to virus 1 40 0.7290848
GO:BP GO:0046483 heterocycle metabolic process 2 4601 0.7290848
GO:BP GO:0051607 defense response to virus 8 223 0.7290848
GO:BP GO:0072089 stem cell proliferation 1 84 0.7295655
GO:BP GO:0050792 regulation of viral process 3 124 0.7300939
GO:BP GO:0006665 sphingolipid metabolic process 2 129 0.7300939
GO:BP GO:0030323 respiratory tube development 1 148 0.7305273
GO:BP GO:0008277 regulation of G protein-coupled receptor signaling pathway 1 93 0.7305273
GO:BP GO:0070296 sarcoplasmic reticulum calcium ion transport 1 32 0.7306392
GO:BP GO:0001934 positive regulation of protein phosphorylation 8 465 0.7306392
GO:BP GO:0032964 collagen biosynthetic process 1 36 0.7306392
GO:BP GO:0055010 ventricular cardiac muscle tissue morphogenesis 1 44 0.7306392
GO:BP GO:0032943 mononuclear cell proliferation 2 168 0.7306392
GO:BP GO:0033555 multicellular organismal response to stress 2 58 0.7306392
GO:BP GO:0051224 negative regulation of protein transport 3 94 0.7306392
GO:BP GO:0140546 defense response to symbiont 8 223 0.7306392
GO:BP GO:0001974 blood vessel remodeling 1 32 0.7306392
GO:BP GO:0060996 dendritic spine development 1 82 0.7308448
GO:BP GO:0141085 regulation of inflammasome-mediated signaling pathway 1 28 0.7310912
GO:BP GO:0043113 receptor clustering 1 40 0.7310912
GO:BP GO:0035196 miRNA processing 1 41 0.7310912
GO:BP GO:0006725 cellular aromatic compound metabolic process 2 4625 0.7312774
GO:BP GO:0032757 positive regulation of interleukin-8 production 1 30 0.7315598
GO:BP GO:0007165 signal transduction 3 3803 0.7315598
GO:BP GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 1 172 0.7315598
GO:BP GO:1903747 regulation of establishment of protein localization to mitochondrion 1 45 0.7315598
GO:BP GO:0043413 macromolecule glycosylation 2 186 0.7323553
GO:BP GO:0006486 protein glycosylation 2 186 0.7323553
GO:BP GO:1902476 chloride transmembrane transport 1 50 0.7344390
GO:BP GO:0007167 enzyme-linked receptor protein signaling pathway 1 741 0.7354506
GO:BP GO:0046651 lymphocyte proliferation 1 162 0.7357743
GO:BP GO:0048260 positive regulation of receptor-mediated endocytosis 1 42 0.7366026
GO:BP GO:0071248 cellular response to metal ion 2 142 0.7377558
GO:BP GO:0048525 negative regulation of viral process 1 65 0.7388113
GO:BP GO:0045619 regulation of lymphocyte differentiation 1 131 0.7388113
GO:BP GO:0140632 canonical inflammasome complex assembly 1 26 0.7389148
GO:BP GO:0002682 regulation of immune system process 1 908 0.7391537
GO:BP GO:0032386 regulation of intracellular transport 8 293 0.7393768
GO:BP GO:0050807 regulation of synapse organization 3 184 0.7399552
GO:BP GO:0033627 cell adhesion mediated by integrin 1 61 0.7400813
GO:BP GO:1903828 negative regulation of protein localization 5 171 0.7406481
GO:BP GO:0006081 cellular aldehyde metabolic process 1 52 0.7413884
GO:BP GO:0019748 secondary metabolic process 1 33 0.7417340
GO:BP GO:0009150 purine ribonucleotide metabolic process 3 292 0.7417340
GO:BP GO:0048546 digestive tract morphogenesis 1 31 0.7425879
GO:BP GO:0034661 ncRNA catabolic process 1 45 0.7428103
GO:BP GO:0050865 regulation of cell activation 1 378 0.7437372
GO:BP GO:0016125 sterol metabolic process 3 108 0.7437372
GO:BP GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 1 27 0.7437552
GO:BP GO:0010586 miRNA metabolic process 2 85 0.7437881
GO:BP GO:0050771 negative regulation of axonogenesis 1 59 0.7437881
GO:BP GO:0072528 pyrimidine-containing compound biosynthetic process 1 34 0.7438635
GO:BP GO:0032101 regulation of response to external stimulus 5 689 0.7444997
GO:BP GO:0032102 negative regulation of response to external stimulus 1 291 0.7444997
GO:BP GO:0097106 postsynaptic density organization 1 30 0.7452070
GO:BP GO:0048878 chemical homeostasis 5 690 0.7452070
GO:BP GO:1904950 negative regulation of establishment of protein localization 1 98 0.7452070
GO:BP GO:0099068 postsynapse assembly 1 31 0.7452070
GO:BP GO:0022414 reproductive process 1 924 0.7452070
GO:BP GO:0072524 pyridine-containing compound metabolic process 1 70 0.7457872
GO:BP GO:0001501 skeletal system development 6 361 0.7457872
GO:BP GO:0042391 regulation of membrane potential 1 295 0.7457872
GO:BP GO:0000003 reproduction 1 933 0.7472959
GO:BP GO:0008306 associative learning 1 65 0.7476280
GO:BP GO:0015711 organic anion transport 1 270 0.7479603
GO:BP GO:0045840 positive regulation of mitotic nuclear division 1 29 0.7496623
GO:BP GO:1901360 organic cyclic compound metabolic process 2 4777 0.7496623
GO:BP GO:0099175 regulation of postsynapse organization 1 83 0.7496623
GO:BP GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 1 44 0.7496623
GO:BP GO:0051321 meiotic cell cycle 1 183 0.7503509
GO:BP GO:0010608 post-transcriptional regulation of gene expression 5 478 0.7503509
GO:BP GO:0010466 negative regulation of peptidase activity 2 123 0.7503509
GO:BP GO:0046148 pigment biosynthetic process 1 47 0.7514243
GO:BP GO:0001658 branching involved in ureteric bud morphogenesis 1 43 0.7514842
GO:BP GO:0030316 osteoclast differentiation 1 65 0.7524217
GO:BP GO:0048806 genitalia development 1 28 0.7528610
GO:BP GO:0031641 regulation of myelination 1 35 0.7528610
GO:BP GO:0050803 regulation of synapse structure or activity 1 188 0.7528610
GO:BP GO:0031018 endocrine pancreas development 1 30 0.7528610
GO:BP GO:0009605 response to external stimulus 1 1637 0.7532387
GO:BP GO:0010647 positive regulation of cell communication 8 1248 0.7532387
GO:BP GO:0016064 immunoglobulin mediated immune response 1 76 0.7538210
GO:BP GO:0035282 segmentation 1 70 0.7562002
GO:BP GO:0071902 positive regulation of protein serine/threonine kinase activity 3 132 0.7572392
GO:BP GO:0072538 T-helper 17 type immune response 1 27 0.7577287
GO:BP GO:0006119 oxidative phosphorylation 2 125 0.7583521
GO:BP GO:0060541 respiratory system development 1 161 0.7583521
GO:BP GO:0006457 protein folding 4 189 0.7585226
GO:BP GO:0141084 inflammasome-mediated signaling pathway 1 28 0.7588630
GO:BP GO:0007215 glutamate receptor signaling pathway 1 29 0.7592595
GO:BP GO:0034032 purine nucleoside bisphosphate metabolic process 1 92 0.7605108
GO:BP GO:0033875 ribonucleoside bisphosphate metabolic process 1 92 0.7605108
GO:BP GO:0033865 nucleoside bisphosphate metabolic process 1 92 0.7605108
GO:BP GO:0019724 B cell mediated immunity 1 77 0.7607772
GO:BP GO:0002253 activation of immune response 3 296 0.7608498
GO:BP GO:0050778 positive regulation of immune response 3 400 0.7608498
GO:BP GO:0072001 renal system development 3 252 0.7608498
GO:BP GO:0006096 glycolytic process 1 74 0.7619572
GO:BP GO:0006066 alcohol metabolic process 1 263 0.7627094
GO:BP GO:0034641 cellular nitrogen compound metabolic process 2 4979 0.7627094
GO:BP GO:1903131 mononuclear cell differentiation 2 295 0.7627094
GO:BP GO:1903311 regulation of mRNA metabolic process 6 255 0.7627094
GO:BP GO:0007595 lactation 1 32 0.7640588
GO:BP GO:0014003 oligodendrocyte development 1 30 0.7654362
GO:BP GO:0048662 negative regulation of smooth muscle cell proliferation 1 39 0.7657360
GO:BP GO:0120161 regulation of cold-induced thermogenesis 1 114 0.7666613
GO:BP GO:0031330 negative regulation of cellular catabolic process 4 170 0.7668970
GO:BP GO:0050433 regulation of catecholamine secretion 1 29 0.7675721
GO:BP GO:0044000 movement in host 2 140 0.7681063
GO:BP GO:0106106 cold-induced thermogenesis 1 115 0.7685662
GO:BP GO:0007265 Ras protein signal transduction 1 287 0.7689191
GO:BP GO:0002269 leukocyte activation involved in inflammatory response 1 21 0.7690494
GO:BP GO:0036230 granulocyte activation 1 19 0.7690494
GO:BP GO:0022612 gland morphogenesis 1 99 0.7692925
GO:BP GO:0009259 ribonucleotide metabolic process 3 309 0.7692925
GO:BP GO:0038127 ERBB signaling pathway 2 103 0.7693117
GO:BP GO:0060348 bone development 2 157 0.7698255
GO:BP GO:0046394 carboxylic acid biosynthetic process 3 224 0.7698407
GO:BP GO:0006812 monoatomic cation transport 3 678 0.7704829
GO:BP GO:2000243 positive regulation of reproductive process 1 51 0.7711635
GO:BP GO:0006940 regulation of smooth muscle contraction 1 39 0.7719525
GO:BP GO:0006576 biogenic amine metabolic process 1 57 0.7719525
GO:BP GO:0032869 cellular response to insulin stimulus 2 168 0.7729455
GO:BP GO:1901566 organonitrogen compound biosynthetic process 22 1497 0.7745474
GO:BP GO:0002088 lens development in camera-type eye 1 57 0.7749383
GO:BP GO:0006821 chloride transport 1 57 0.7749383
GO:BP GO:0016053 organic acid biosynthetic process 3 225 0.7749383
GO:BP GO:0043410 positive regulation of MAPK cascade 1 316 0.7760684
GO:BP GO:0098657 import into cell 4 662 0.7776193
GO:BP GO:0048469 cell maturation 3 110 0.7788167
GO:BP GO:0003229 ventricular cardiac muscle tissue development 1 53 0.7788567
GO:BP GO:0050870 positive regulation of T cell activation 1 144 0.7789609
GO:BP GO:0050789 regulation of biological process 8 8024 0.7793075
GO:BP GO:0002697 regulation of immune effector process 2 195 0.7793075
GO:BP GO:0007275 multicellular organism development 3 3348 0.7793075
GO:BP GO:0006968 cellular defense response 1 15 0.7800174
GO:BP GO:0140013 meiotic nuclear division 2 117 0.7800174
GO:BP GO:0001938 positive regulation of endothelial cell proliferation 1 74 0.7800174
GO:BP GO:0033108 mitochondrial respiratory chain complex assembly 2 96 0.7800174
GO:BP GO:0035966 response to topologically incorrect protein 3 148 0.7800174
GO:BP GO:0019693 ribose phosphate metabolic process 3 317 0.7806816
GO:BP GO:0060675 ureteric bud morphogenesis 1 49 0.7812234
GO:BP GO:0072593 reactive oxygen species metabolic process 1 157 0.7824233
GO:BP GO:0023052 signaling 3 4134 0.7827427
GO:BP GO:1901654 response to ketone 2 144 0.7827427
GO:BP GO:0099084 postsynaptic specialization organization 1 36 0.7840843
GO:BP GO:0072171 mesonephric tubule morphogenesis 1 50 0.7860252
GO:BP GO:0042093 T-helper cell differentiation 1 44 0.7867478
GO:BP GO:0008202 steroid metabolic process 6 203 0.7867478
GO:BP GO:0050432 catecholamine secretion 1 33 0.7867824
GO:BP GO:0099173 postsynapse organization 2 159 0.7870988
GO:BP GO:0007127 meiosis I 1 73 0.7871750
GO:BP GO:0007565 female pregnancy 4 123 0.7872317
GO:BP GO:0007268 chemical synaptic transmission 2 490 0.7872317
GO:BP GO:0098916 anterograde trans-synaptic signaling 2 490 0.7872317
GO:BP GO:0061951 establishment of protein localization to plasma membrane 1 59 0.7872317
GO:BP GO:0001523 retinoid metabolic process 1 39 0.7872317
GO:BP GO:0002366 leukocyte activation involved in immune response 2 158 0.7872317
GO:BP GO:0048592 eye morphogenesis 2 114 0.7872373
GO:BP GO:0009408 response to heat 1 74 0.7876847
GO:BP GO:0051262 protein tetramerization 1 64 0.7876847
GO:BP GO:0048589 developmental growth 7 523 0.7876847
GO:BP GO:0005975 carbohydrate metabolic process 1 439 0.7892067
GO:BP GO:0098661 inorganic anion transmembrane transport 1 64 0.7897331
GO:BP GO:0099537 trans-synaptic signaling 2 494 0.7897331
GO:BP GO:0030879 mammary gland development 1 105 0.7897331
GO:BP GO:0090316 positive regulation of intracellular protein transport 1 135 0.7915252
GO:BP GO:0009617 response to bacterium 4 326 0.7917604
GO:BP GO:0002263 cell activation involved in immune response 2 161 0.7919914
GO:BP GO:0007154 cell communication 3 4210 0.7919914
GO:BP GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 1 44 0.7927426
GO:BP GO:0009100 glycoprotein metabolic process 3 316 0.7927426
GO:BP GO:0046330 positive regulation of JNK cascade 1 71 0.7937380
GO:BP GO:0050906 detection of stimulus involved in sensory perception 1 38 0.7942320
GO:BP GO:0018198 peptidyl-cysteine modification 1 41 0.7947954
GO:BP GO:2000677 regulation of transcription regulatory region DNA binding 1 43 0.7947954
GO:BP GO:0048519 negative regulation of biological process 30 4025 0.7950759
GO:BP GO:0030003 intracellular monoatomic cation homeostasis 1 364 0.7955659
GO:BP GO:0038061 non-canonical NF-kappaB signal transduction 2 94 0.7955659
GO:BP GO:0002287 alpha-beta T cell activation involved in immune response 1 44 0.7959021
GO:BP GO:0002293 alpha-beta T cell differentiation involved in immune response 1 44 0.7959021
GO:BP GO:0016101 diterpenoid metabolic process 1 42 0.7959681
GO:BP GO:0010556 regulation of macromolecule biosynthetic process 82 3705 0.7959681
GO:BP GO:1990845 adaptive thermogenesis 1 126 0.7959681
GO:BP GO:0061982 meiosis I cell cycle process 1 77 0.7982088
GO:BP GO:0019229 regulation of vasoconstriction 1 38 0.7984454
GO:BP GO:0098771 inorganic ion homeostasis 1 355 0.7991823
GO:BP GO:2000649 regulation of sodium ion transmembrane transporter activity 1 42 0.7994251
GO:BP GO:0006873 intracellular monoatomic ion homeostasis 1 369 0.8002824
GO:BP GO:1903039 positive regulation of leukocyte cell-cell adhesion 1 157 0.8027984
GO:BP GO:0010035 response to inorganic substance 1 393 0.8029131
GO:BP GO:0099536 synaptic signaling 2 512 0.8031071
GO:BP GO:0015695 organic cation transport 1 35 0.8031646
GO:BP GO:0002931 response to ischemia 1 48 0.8040220
GO:BP GO:0016126 sterol biosynthetic process 1 53 0.8064533
GO:BP GO:0051701 biological process involved in interaction with host 2 153 0.8075436
GO:BP GO:0048562 embryonic organ morphogenesis 5 186 0.8075436
GO:BP GO:0014009 glial cell proliferation 1 40 0.8077016
GO:BP GO:0048771 tissue remodeling 3 115 0.8089128
GO:BP GO:0002534 cytokine production involved in inflammatory response 1 35 0.8096992
GO:BP GO:1900015 regulation of cytokine production involved in inflammatory response 1 35 0.8096992
GO:BP GO:0003206 cardiac chamber morphogenesis 2 110 0.8096992
GO:BP GO:0015908 fatty acid transport 2 58 0.8097325
GO:BP GO:0032677 regulation of interleukin-8 production 1 42 0.8097325
GO:BP GO:0032637 interleukin-8 production 1 42 0.8097325
GO:BP GO:0021987 cerebral cortex development 1 102 0.8110393
GO:BP GO:0045453 bone resorption 1 41 0.8122675
GO:BP GO:0050793 regulation of developmental process 2 1810 0.8135069
GO:BP GO:0007166 cell surface receptor signaling pathway 1 1889 0.8152205
GO:BP GO:0071345 cellular response to cytokine stimulus 9 544 0.8153765
GO:BP GO:0042110 T cell activation 2 317 0.8156815
GO:BP GO:0097194 execution phase of apoptosis 1 52 0.8163223
GO:BP GO:1901137 carbohydrate derivative biosynthetic process 5 546 0.8183235
GO:BP GO:0072078 nephron tubule morphogenesis 1 58 0.8192845
GO:BP GO:0034097 response to cytokine 5 608 0.8201060
GO:BP GO:1903046 meiotic cell cycle process 2 132 0.8201060
GO:BP GO:0070231 T cell apoptotic process 1 41 0.8201060
GO:BP GO:0010038 response to metal ion 3 261 0.8201060
GO:BP GO:0048871 multicellular organismal-level homeostasis 2 569 0.8243077
GO:BP GO:0043954 cellular component maintenance 1 60 0.8243077
GO:BP GO:0009308 amine metabolic process 1 68 0.8244642
GO:BP GO:0002292 T cell differentiation involved in immune response 1 46 0.8260997
GO:BP GO:0070663 regulation of leukocyte proliferation 1 140 0.8264725
GO:BP GO:0072088 nephron epithelium morphogenesis 1 60 0.8266877
GO:BP GO:0006672 ceramide metabolic process 1 81 0.8274458
GO:BP GO:1904035 regulation of epithelial cell apoptotic process 1 74 0.8279605
GO:BP GO:0098656 monoatomic anion transmembrane transport 1 80 0.8292324
GO:BP GO:0032271 regulation of protein polymerization 1 164 0.8292543
GO:BP GO:0031638 zymogen activation 1 46 0.8294911
GO:BP GO:0006766 vitamin metabolic process 1 75 0.8305783
GO:BP GO:0034728 nucleosome organization 2 86 0.8317470
GO:BP GO:0031334 positive regulation of protein-containing complex assembly 1 161 0.8317470
GO:BP GO:0035239 tube morphogenesis 1 663 0.8317470
GO:BP GO:0006721 terpenoid metabolic process 1 49 0.8317470
GO:BP GO:0010633 negative regulation of epithelial cell migration 1 53 0.8322566
GO:BP GO:2000241 regulation of reproductive process 2 126 0.8322566
GO:BP GO:0061333 renal tubule morphogenesis 1 62 0.8325581
GO:BP GO:0072028 nephron morphogenesis 1 62 0.8325581
GO:BP GO:0071346 cellular response to type II interferon 1 68 0.8325581
GO:BP GO:0045665 negative regulation of neuron differentiation 1 44 0.8330262
GO:BP GO:0071887 leukocyte apoptotic process 2 82 0.8333067
GO:BP GO:0002437 inflammatory response to antigenic stimulus 1 38 0.8336997
GO:BP GO:0051785 positive regulation of nuclear division 1 38 0.8336997
GO:BP GO:0048813 dendrite morphogenesis 1 116 0.8338036
GO:BP GO:0010257 NADH dehydrogenase complex assembly 1 57 0.8340004
GO:BP GO:0032981 mitochondrial respiratory chain complex I assembly 1 57 0.8340004
GO:BP GO:0055080 monoatomic cation homeostasis 1 410 0.8340004
GO:BP GO:0086065 cell communication involved in cardiac conduction 1 58 0.8343475
GO:BP GO:0030148 sphingolipid biosynthetic process 1 87 0.8360112
GO:BP GO:0032508 DNA duplex unwinding 1 74 0.8375530
GO:BP GO:0045682 regulation of epidermis development 1 44 0.8375530
GO:BP GO:0006220 pyrimidine nucleotide metabolic process 1 47 0.8378423
GO:BP GO:0007259 receptor signaling pathway via JAK-STAT 2 89 0.8378423
GO:BP GO:0050801 monoatomic ion homeostasis 1 416 0.8380854
GO:BP GO:0006090 pyruvate metabolic process 1 97 0.8383407
GO:BP GO:0003208 cardiac ventricle morphogenesis 1 62 0.8386493
GO:BP GO:0048255 mRNA stabilization 1 52 0.8424005
GO:BP GO:0098662 inorganic cation transmembrane transport 2 538 0.8424641
GO:BP GO:0048513 animal organ development 1 2153 0.8454674
GO:BP GO:0051384 response to glucocorticoid 1 82 0.8456557
GO:BP GO:0045600 positive regulation of fat cell differentiation 1 50 0.8464593
GO:BP GO:0002274 myeloid leukocyte activation 1 121 0.8464593
GO:BP GO:0043406 positive regulation of MAP kinase activity 1 82 0.8468165
GO:BP GO:0007204 positive regulation of cytosolic calcium ion concentration 1 78 0.8468165
GO:BP GO:0042440 pigment metabolic process 1 60 0.8468165
GO:BP GO:0021782 glial cell development 2 87 0.8468165
GO:BP GO:0044703 multi-organism reproductive process 4 132 0.8476153
GO:BP GO:0022409 positive regulation of cell-cell adhesion 1 188 0.8476626
GO:BP GO:1902305 regulation of sodium ion transmembrane transport 1 50 0.8483714
GO:BP GO:1902105 regulation of leukocyte differentiation 1 197 0.8483714
GO:BP GO:0030534 adult behavior 1 94 0.8503725
GO:BP GO:2000027 regulation of animal organ morphogenesis 1 102 0.8503725
GO:BP GO:0051937 catecholamine transport 1 41 0.8505369
GO:BP GO:0001570 vasculogenesis 1 67 0.8519480
GO:BP GO:0031099 regeneration 3 142 0.8523711
GO:BP GO:0098655 monoatomic cation transmembrane transport 2 555 0.8526728
GO:BP GO:0010811 positive regulation of cell-substrate adhesion 1 99 0.8526728
GO:BP GO:0045921 positive regulation of exocytosis 1 58 0.8526728
GO:BP GO:0097696 receptor signaling pathway via STAT 2 92 0.8527269
GO:BP GO:1903533 regulation of protein targeting 1 67 0.8529915
GO:BP GO:0043367 CD4-positive, alpha-beta T cell differentiation 1 54 0.8544490
GO:BP GO:0050684 regulation of mRNA processing 2 114 0.8545785
GO:BP GO:0051251 positive regulation of lymphocyte activation 1 200 0.8551788
GO:BP GO:0051606 detection of stimulus 1 109 0.8551788
GO:BP GO:0019637 organophosphate metabolic process 2 775 0.8551788
GO:BP GO:0009620 response to fungus 1 22 0.8553643
GO:BP GO:0032388 positive regulation of intracellular transport 3 174 0.8554160
GO:BP GO:0070372 regulation of ERK1 and ERK2 cascade 1 192 0.8554160
GO:BP GO:0032392 DNA geometric change 1 80 0.8555820
GO:BP GO:1902893 regulation of miRNA transcription 1 58 0.8556018
GO:BP GO:0006163 purine nucleotide metabolic process 3 369 0.8559295
GO:BP GO:0042773 ATP synthesis coupled electron transport 1 84 0.8559295
GO:BP GO:0042775 mitochondrial ATP synthesis coupled electron transport 1 84 0.8559295
GO:BP GO:0001817 regulation of cytokine production 4 475 0.8572373
GO:BP GO:0030218 erythrocyte differentiation 2 109 0.8574330
GO:BP GO:0065007 biological regulation 8 8289 0.8574975
GO:BP GO:0051092 positive regulation of NF-kappaB transcription factor activity 1 116 0.8577343
GO:BP GO:0061614 miRNA transcription 1 59 0.8587798
GO:BP GO:0006811 monoatomic ion transport 3 789 0.8587832
GO:BP GO:0002521 leukocyte differentiation 2 387 0.8595601
GO:BP GO:0031326 regulation of cellular biosynthetic process 1 3797 0.8597609
GO:BP GO:0001816 cytokine production 4 479 0.8608455
GO:BP GO:0009889 regulation of biosynthetic process 1 3823 0.8618605
GO:BP GO:0008203 cholesterol metabolic process 2 99 0.8626706
GO:BP GO:0002757 immune response-activating signaling pathway 2 258 0.8626706
GO:BP GO:0048731 system development 3 2881 0.8633952
GO:BP GO:0051881 regulation of mitochondrial membrane potential 1 63 0.8651823
GO:BP GO:0015698 inorganic anion transport 1 87 0.8651823
GO:BP GO:0006879 intracellular iron ion homeostasis 1 57 0.8654795
GO:BP GO:0006954 inflammatory response 3 451 0.8654795
GO:BP GO:0014855 striated muscle cell proliferation 1 58 0.8654795
GO:BP GO:0045069 regulation of viral genome replication 1 64 0.8677347
GO:BP GO:0006820 monoatomic anion transport 1 92 0.8677347
GO:BP GO:0032874 positive regulation of stress-activated MAPK cascade 1 95 0.8677347
GO:BP GO:0042310 vasoconstriction 1 51 0.8677347
GO:BP GO:1902075 cellular response to salt 1 144 0.8680981
GO:BP GO:0019222 regulation of metabolic process 105 5002 0.8684004
GO:BP GO:0042246 tissue regeneration 1 54 0.8685333
GO:BP GO:0009060 aerobic respiration 2 171 0.8690202
GO:BP GO:0002699 positive regulation of immune effector process 1 135 0.8690202
GO:BP GO:0042130 negative regulation of T cell proliferation 1 38 0.8701370
GO:BP GO:0061448 connective tissue development 2 212 0.8702583
GO:BP GO:0010822 positive regulation of mitochondrion organization 1 66 0.8708248
GO:BP GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 1 97 0.8710201
GO:BP GO:0048640 negative regulation of developmental growth 1 94 0.8719456
GO:BP GO:0034341 response to type II interferon 1 82 0.8721239
GO:BP GO:0006986 response to unfolded protein 2 126 0.8721239
GO:BP GO:0070371 ERK1 and ERK2 cascade 1 211 0.8721746
GO:BP GO:0043489 RNA stabilization 1 61 0.8723244
GO:BP GO:0070192 chromosome organization involved in meiotic cell cycle 1 35 0.8737581
GO:BP GO:1901615 organic hydroxy compound metabolic process 1 375 0.8742545
GO:BP GO:0006635 fatty acid beta-oxidation 1 68 0.8743005
GO:BP GO:0001936 regulation of endothelial cell proliferation 1 102 0.8753960
GO:BP GO:0046434 organophosphate catabolic process 1 113 0.8753960
GO:BP GO:1902373 negative regulation of mRNA catabolic process 1 59 0.8754915
GO:BP GO:0071103 DNA conformation change 1 87 0.8757185
GO:BP GO:0098660 inorganic ion transmembrane transport 2 583 0.8758883
GO:BP GO:0060993 kidney morphogenesis 1 73 0.8758883
GO:BP GO:0001657 ureteric bud development 1 75 0.8758883
GO:BP GO:0061351 neural precursor cell proliferation 1 122 0.8759322
GO:BP GO:0016079 synaptic vesicle exocytosis 1 74 0.8759322
GO:BP GO:0097009 energy homeostasis 1 59 0.8763023
GO:BP GO:0031323 regulation of cellular metabolic process 96 4568 0.8768026
GO:BP GO:0034101 erythrocyte homeostasis 2 116 0.8776361
GO:BP GO:0072163 mesonephric epithelium development 1 76 0.8776361
GO:BP GO:0072164 mesonephric tubule development 1 76 0.8776361
GO:BP GO:0050868 negative regulation of T cell activation 2 67 0.8780451
GO:BP GO:0015980 energy derivation by oxidation of organic compounds 1 290 0.8781755
GO:BP GO:0002285 lymphocyte activation involved in immune response 1 116 0.8782525
GO:BP GO:0051240 positive regulation of multicellular organismal process 1 1102 0.8782525
GO:BP GO:0070918 regulatory ncRNA processing 1 58 0.8795178
GO:BP GO:1903037 regulation of leukocyte cell-cell adhesion 1 210 0.8798033
GO:BP GO:0001822 kidney development 1 245 0.8800496
GO:BP GO:0002764 immune response-regulating signaling pathway 2 269 0.8805792
GO:BP GO:0006493 protein O-linked glycosylation 1 75 0.8817864
GO:BP GO:0002832 negative regulation of response to biotic stimulus 1 102 0.8828606
GO:BP GO:1902652 secondary alcohol metabolic process 2 106 0.8832463
GO:BP GO:0002684 positive regulation of immune system process 5 609 0.8832463
GO:BP GO:0001775 cell activation 1 655 0.8832463
GO:BP GO:0051239 regulation of multicellular organismal process 2 2048 0.8832463
GO:BP GO:0031016 pancreas development 1 51 0.8832479
GO:BP GO:1904019 epithelial cell apoptotic process 1 101 0.8832959
GO:BP GO:0002696 positive regulation of leukocyte activation 1 222 0.8834459
GO:BP GO:0032760 positive regulation of tumor necrosis factor production 1 54 0.8837227
GO:BP GO:0048568 embryonic organ development 4 314 0.8837227
GO:BP GO:0050863 regulation of T cell activation 1 215 0.8837227
GO:BP GO:0046849 bone remodeling 1 60 0.8838140
GO:BP GO:0001823 mesonephros development 1 77 0.8849611
GO:BP GO:0001764 neuron migration 1 133 0.8862537
GO:BP GO:0002440 production of molecular mediator of immune response 1 133 0.8868736
GO:BP GO:0007267 cell-cell signaling 1 1149 0.8885064
GO:BP GO:0002532 production of molecular mediator involved in inflammatory response 1 52 0.8912143
GO:BP GO:0007584 response to nutrient 1 107 0.8917484
GO:BP GO:0019221 cytokine-mediated signaling pathway 2 280 0.8927150
GO:BP GO:0070936 protein K48-linked ubiquitination 1 77 0.8930452
GO:BP GO:0050867 positive regulation of cell activation 1 227 0.8930452
GO:BP GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 1 56 0.8933928
GO:BP GO:0002181 cytoplasmic translation 2 150 0.8951973
GO:BP GO:0060021 roof of mouth development 1 71 0.8970665
GO:BP GO:0022904 respiratory electron transport chain 1 106 0.9011816
GO:BP GO:0021700 developmental maturation 4 213 0.9017099
GO:BP GO:0030154 cell differentiation 3 2938 0.9017099
GO:BP GO:0048869 cellular developmental process 3 2939 0.9017099
GO:BP GO:0009117 nucleotide metabolic process 3 422 0.9022763
GO:BP GO:0034329 cell junction assembly 1 346 0.9022763
GO:BP GO:0010975 regulation of neuron projection development 1 373 0.9029490
GO:BP GO:0007159 leukocyte cell-cell adhesion 1 233 0.9029490
GO:BP GO:0009615 response to virus 8 294 0.9030039
GO:BP GO:0071695 anatomical structure maturation 3 157 0.9030039
GO:BP GO:1903038 negative regulation of leukocyte cell-cell adhesion 2 74 0.9039303
GO:BP GO:0034655 nucleobase-containing compound catabolic process 4 367 0.9049336
GO:BP GO:0009152 purine ribonucleotide biosynthetic process 1 179 0.9055084
GO:BP GO:0035710 CD4-positive, alpha-beta T cell activation 1 68 0.9055084
GO:BP GO:0051279 regulation of release of sequestered calcium ion into cytosol 1 60 0.9055776
GO:BP GO:0048856 anatomical structure development 3 4094 0.9056881
GO:BP GO:0006720 isoprenoid metabolic process 1 84 0.9057203
GO:BP GO:0007272 ensheathment of neurons 2 115 0.9057203
GO:BP GO:0008366 axon ensheathment 2 115 0.9057203
GO:BP GO:0060249 anatomical structure homeostasis 2 179 0.9060972
GO:BP GO:0001894 tissue homeostasis 2 179 0.9060972
GO:BP GO:0006753 nucleoside phosphate metabolic process 3 428 0.9068392
GO:BP GO:0034220 monoatomic ion transmembrane transport 2 651 0.9071950
GO:BP GO:0001935 endothelial cell proliferation 1 120 0.9086374
GO:BP GO:0033273 response to vitamin 1 63 0.9098589
GO:BP GO:0002286 T cell activation involved in immune response 1 59 0.9098589
GO:BP GO:0050672 negative regulation of lymphocyte proliferation 1 46 0.9102076
GO:BP GO:0042445 hormone metabolic process 2 132 0.9107855
GO:BP GO:0032945 negative regulation of mononuclear cell proliferation 1 46 0.9128979
GO:BP GO:0030183 B cell differentiation 2 91 0.9128979
GO:BP GO:0046632 alpha-beta T cell differentiation 1 71 0.9132833
GO:BP GO:0070972 protein localization to endoplasmic reticulum 2 81 0.9136277
GO:BP GO:0016070 RNA metabolic process 1 3634 0.9140750
GO:BP GO:0008543 fibroblast growth factor receptor signaling pathway 1 59 0.9151030
GO:BP GO:0002064 epithelial cell development 1 155 0.9161525
GO:BP GO:0006626 protein targeting to mitochondrion 1 100 0.9162828
GO:BP GO:0019217 regulation of fatty acid metabolic process 1 68 0.9162828
GO:BP GO:0015718 monocarboxylic acid transport 1 91 0.9166150
GO:BP GO:0050808 synapse organization 1 372 0.9171072
GO:BP GO:0016358 dendrite development 2 193 0.9171072
GO:BP GO:0035418 protein localization to synapse 1 68 0.9175274
GO:BP GO:0002028 regulation of sodium ion transport 1 71 0.9175274
GO:BP GO:0043491 phosphatidylinositol 3-kinase/protein kinase B signal transduction 2 144 0.9175274
GO:BP GO:0009260 ribonucleotide biosynthetic process 1 192 0.9175274
GO:BP GO:1990778 protein localization to cell periphery 2 301 0.9175274
GO:BP GO:0006939 smooth muscle contraction 1 71 0.9178542
GO:BP GO:0071805 potassium ion transmembrane transport 1 129 0.9178542
GO:BP GO:0009791 post-embryonic development 1 76 0.9213593
GO:BP GO:0042742 defense response to bacterium 1 98 0.9224403
GO:BP GO:0002694 regulation of leukocyte activation 2 346 0.9231329
GO:BP GO:0046390 ribose phosphate biosynthetic process 1 199 0.9237387
GO:BP GO:0046700 heterocycle catabolic process 1 389 0.9237387
GO:BP GO:0044270 cellular nitrogen compound catabolic process 1 386 0.9237387
GO:BP GO:0032147 activation of protein kinase activity 1 82 0.9237387
GO:BP GO:0006029 proteoglycan metabolic process 1 77 0.9237387
GO:BP GO:0046649 lymphocyte activation 2 469 0.9255435
GO:BP GO:0032501 multicellular organismal process 4 4801 0.9294253
GO:BP GO:0042542 response to hydrogen peroxide 1 85 0.9294492
GO:BP GO:0045807 positive regulation of endocytosis 2 104 0.9294492
GO:BP GO:0045333 cellular respiration 2 214 0.9309509
GO:BP GO:0072527 pyrimidine-containing compound metabolic process 1 69 0.9313352
GO:BP GO:0032963 collagen metabolic process 1 72 0.9315014
GO:BP GO:0045132 meiotic chromosome segregation 1 51 0.9315014
GO:BP GO:0019439 aromatic compound catabolic process 1 396 0.9315014
GO:BP GO:0050768 negative regulation of neurogenesis 1 113 0.9320298
GO:BP GO:0006164 purine nucleotide biosynthetic process 3 210 0.9328104
GO:BP GO:0022407 regulation of cell-cell adhesion 1 292 0.9328104
GO:BP GO:0045785 positive regulation of cell adhesion 1 319 0.9328104
GO:BP GO:0009952 anterior/posterior pattern specification 1 125 0.9328104
GO:BP GO:1903312 negative regulation of mRNA metabolic process 1 84 0.9328104
GO:BP GO:0042113 B cell activation 1 169 0.9328104
GO:BP GO:0090304 nucleic acid metabolic process 1 4081 0.9336572
GO:BP GO:0061337 cardiac conduction 1 88 0.9339387
GO:BP GO:0032465 regulation of cytokinesis 1 77 0.9351641
GO:BP GO:0007600 sensory perception 1 259 0.9361107
GO:BP GO:0060349 bone morphogenesis 1 74 0.9365062
GO:BP GO:0006334 nucleosome assembly 1 69 0.9370855
GO:BP GO:0000395 mRNA 5’-splice site recognition 1 9 0.9370855
GO:BP GO:0002573 myeloid leukocyte differentiation 1 154 0.9376595
GO:BP GO:0042180 cellular ketone metabolic process 1 161 0.9384102
GO:BP GO:0051961 negative regulation of nervous system development 1 119 0.9393474
GO:BP GO:1901361 organic cyclic compound catabolic process 1 413 0.9403652
GO:BP GO:0032502 developmental process 3 4441 0.9404314
GO:BP GO:0009062 fatty acid catabolic process 1 89 0.9404314
GO:BP GO:0051249 regulation of lymphocyte activation 1 296 0.9406343
GO:BP GO:0072522 purine-containing compound biosynthetic process 3 219 0.9409086
GO:BP GO:0051250 negative regulation of lymphocyte activation 2 89 0.9409086
GO:BP GO:0002027 regulation of heart rate 1 85 0.9421446
GO:BP GO:0097529 myeloid leukocyte migration 1 118 0.9421446
GO:BP GO:0019395 fatty acid oxidation 1 91 0.9429240
GO:BP GO:0072655 establishment of protein localization to mitochondrion 1 117 0.9429240
GO:BP GO:0001944 vasculature development 1 562 0.9431633
GO:BP GO:0048024 regulation of mRNA splicing, via spliceosome 1 92 0.9431633
GO:BP GO:0007029 endoplasmic reticulum organization 1 91 0.9439236
GO:BP GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 2 471 0.9463732
GO:BP GO:0072659 protein localization to plasma membrane 3 250 0.9472540
GO:BP GO:0007269 neurotransmitter secretion 1 105 0.9488010
GO:BP GO:0099643 signal release from synapse 1 105 0.9488010
GO:BP GO:0045765 regulation of angiogenesis 1 200 0.9504101
GO:BP GO:0034440 lipid oxidation 1 92 0.9521375
GO:BP GO:1901342 regulation of vasculature development 1 202 0.9521375
GO:BP GO:0070585 protein localization to mitochondrion 1 123 0.9535316
GO:BP GO:0001667 ameboidal-type cell migration 3 358 0.9540657
GO:BP GO:0016579 protein deubiquitination 1 127 0.9563269
GO:BP GO:0006376 mRNA splice site recognition 1 33 0.9566216
GO:BP GO:0010810 regulation of cell-substrate adhesion 1 171 0.9577183
GO:BP GO:0030168 platelet activation 1 90 0.9581046
GO:BP GO:0006091 generation of precursor metabolites and energy 1 425 0.9581046
GO:BP GO:0051091 positive regulation of DNA-binding transcription factor activity 1 198 0.9592021
GO:BP GO:0030258 lipid modification 2 157 0.9596930
GO:BP GO:0009165 nucleotide biosynthetic process 1 242 0.9601433
GO:BP GO:0046660 female sex differentiation 1 91 0.9603410
GO:BP GO:1901293 nucleoside phosphate biosynthetic process 1 243 0.9609112
GO:BP GO:0006397 mRNA processing 7 455 0.9618794
GO:BP GO:0048565 digestive tract development 1 92 0.9618794
GO:BP GO:0044344 cellular response to fibroblast growth factor stimulus 1 81 0.9618794
GO:BP GO:0045321 leukocyte activation 3 556 0.9618794
GO:BP GO:1903900 regulation of viral life cycle 1 101 0.9618794
GO:BP GO:0022900 electron transport chain 1 144 0.9618794
GO:BP GO:0070374 positive regulation of ERK1 and ERK2 cascade 1 120 0.9618794
GO:BP GO:0016441 post-transcriptional gene silencing 1 72 0.9645307
GO:BP GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway 1 71 0.9665274
GO:BP GO:1902414 protein localization to cell junction 1 94 0.9679875
GO:BP GO:0016071 mRNA metabolic process 8 673 0.9686060
GO:BP GO:0022603 regulation of anatomical structure morphogenesis 2 679 0.9693059
GO:BP GO:0045598 regulation of fat cell differentiation 1 100 0.9693971
GO:BP GO:0070646 protein modification by small protein removal 1 145 0.9693971
GO:BP GO:0045596 negative regulation of cell differentiation 1 469 0.9693971
GO:BP GO:0006614 SRP-dependent cotranslational protein targeting to membrane 1 32 0.9693971
GO:BP GO:0046631 alpha-beta T cell activation 1 93 0.9693971
GO:BP GO:0072329 monocarboxylic acid catabolic process 1 105 0.9697609
GO:BP GO:0006807 nitrogen compound metabolic process 2 7500 0.9697609
GO:BP GO:0010565 regulation of cellular ketone metabolic process 1 101 0.9702665
GO:BP GO:0022408 negative regulation of cell-cell adhesion 2 115 0.9702665
GO:BP GO:0071774 response to fibroblast growth factor 1 85 0.9702665
GO:BP GO:0006613 cotranslational protein targeting to membrane 1 37 0.9710629
GO:BP GO:0055123 digestive system development 1 100 0.9719717
GO:BP GO:1902074 response to salt 1 261 0.9724907
GO:BP GO:0002695 negative regulation of leukocyte activation 2 103 0.9724916
GO:BP GO:0022613 ribonucleoprotein complex biogenesis 1 469 0.9735397
GO:BP GO:0031047 regulatory ncRNA-mediated gene silencing 1 121 0.9760951
GO:BP GO:0035270 endocrine system development 1 85 0.9767263
GO:BP GO:0043170 macromolecule metabolic process 2 7153 0.9776408
GO:BP GO:0008380 RNA splicing 5 430 0.9776666
GO:BP GO:0050877 nervous system process 3 627 0.9777195
GO:BP GO:0010467 gene expression 1 4798 0.9777195
GO:BP GO:0045047 protein targeting to ER 1 52 0.9777195
GO:BP GO:0072599 establishment of protein localization to endoplasmic reticulum 1 56 0.9790879
GO:BP GO:0051209 release of sequestered calcium ion into cytosol 1 90 0.9790879
GO:BP GO:0051283 negative regulation of sequestering of calcium ion 1 91 0.9797380
GO:BP GO:0042592 homeostatic process 5 1189 0.9799754
GO:BP GO:0034330 cell junction organization 1 585 0.9803175
GO:BP GO:0051282 regulation of sequestering of calcium ion 1 93 0.9807406
GO:BP GO:0001505 regulation of neurotransmitter levels 1 132 0.9807406
GO:BP GO:0042060 wound healing 2 304 0.9822143
GO:BP GO:0001819 positive regulation of cytokine production 1 283 0.9824052
GO:BP GO:0051208 sequestering of calcium ion 1 97 0.9828422
GO:BP GO:0001890 placenta development 1 116 0.9828422
GO:BP GO:0001508 action potential 1 106 0.9828422
GO:BP GO:0042552 myelination 1 113 0.9839542
GO:BP GO:0050866 negative regulation of cell activation 2 121 0.9841375
GO:BP GO:1901136 carbohydrate derivative catabolic process 1 137 0.9842498
GO:BP GO:0009059 macromolecule biosynthetic process 1 5214 0.9855186
GO:BP GO:0031589 cell-substrate adhesion 2 271 0.9861253
GO:BP GO:0008154 actin polymerization or depolymerization 1 157 0.9862142
GO:BP GO:0044238 primary metabolic process 2 7855 0.9866429
GO:BP GO:0006836 neurotransmitter transport 1 141 0.9879731
GO:BP GO:0009611 response to wounding 3 394 0.9881818
GO:BP GO:0007608 sensory perception of smell 1 15 0.9888130
GO:BP GO:0016054 organic acid catabolic process 2 187 0.9901511
GO:BP GO:0030155 regulation of cell adhesion 1 535 0.9901511
GO:BP GO:0046395 carboxylic acid catabolic process 2 187 0.9901511
GO:BP GO:1902600 proton transmembrane transport 1 119 0.9912081
GO:BP GO:0006261 DNA-templated DNA replication 1 150 0.9927772
GO:BP GO:0044237 cellular metabolic process 2 7633 0.9931985
GO:BP GO:0000245 spliceosomal complex assembly 1 76 0.9953631
GO:BP GO:0006814 sodium ion transport 2 158 0.9954914
GO:BP GO:0002768 immune response-regulating cell surface receptor signaling pathway 1 165 0.9957526
GO:BP GO:0044249 cellular biosynthetic process 1 5878 0.9963829
GO:BP GO:0010721 negative regulation of cell development 1 190 0.9964051
GO:BP GO:0000398 mRNA splicing, via spliceosome 2 292 0.9964051
GO:BP GO:0042129 regulation of T cell proliferation 1 94 0.9964051
GO:BP GO:0000375 RNA splicing, via transesterification reactions 2 296 0.9964051
GO:BP GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 2 292 0.9964051
GO:BP GO:1901576 organic substance biosynthetic process 1 5940 0.9964051
GO:BP GO:0009058 biosynthetic process 1 5977 0.9964051
GO:BP GO:0007606 sensory perception of chemical stimulus 1 29 0.9967863
GO:BP GO:0035725 sodium ion transmembrane transport 1 112 0.9976287
GO:BP GO:0007601 visual perception 1 97 0.9980868
GO:BP GO:0007596 blood coagulation 1 150 0.9983282
GO:BP GO:0050953 sensory perception of light stimulus 1 98 0.9983282
GO:BP GO:0050817 coagulation 1 153 0.9990247
GO:BP GO:0007599 hemostasis 1 154 0.9990247
GO:BP GO:0051302 regulation of cell division 1 140 0.9990247
GO:BP GO:0010632 regulation of epithelial cell migration 1 195 0.9991636
GO:BP GO:0010631 epithelial cell migration 2 253 0.9991636
GO:BP GO:0090132 epithelium migration 2 253 0.9991636
GO:BP GO:0001525 angiogenesis 1 389 0.9991636
GO:BP GO:0090130 tissue migration 2 257 0.9992281
GO:BP GO:0035194 regulatory ncRNA-mediated post-transcriptional gene silencing 1 64 0.9992281
GO:BP GO:0035195 miRNA-mediated post-transcriptional gene silencing 1 59 0.9992281
GO:BP GO:0007162 negative regulation of cell adhesion 2 191 0.9998629
GO:BP GO:0000365 mRNA trans splicing, via spliceosome 1 7 1.0000000
GO:BP GO:0006396 RNA processing 5 988 1.0000000
GO:BP GO:0032944 regulation of mononuclear cell proliferation 1 128 1.0000000
GO:BP GO:2000147 positive regulation of cell motility 2 422 1.0000000
GO:BP GO:0009987 cellular process 1 11490 1.0000000
GO:BP GO:0071826 protein-RNA complex organization 1 216 1.0000000
GO:BP GO:0071704 organic substance metabolic process 2 8244 1.0000000
GO:BP GO:0040017 positive regulation of locomotion 2 430 1.0000000
GO:BP GO:0006959 humoral immune response 1 82 1.0000000
GO:BP GO:0030335 positive regulation of cell migration 2 408 1.0000000
GO:BP GO:0000353 formation of quadruple SL/U4/U5/U6 snRNP 1 7 1.0000000
GO:BP GO:0007548 sex differentiation 1 193 1.0000000
GO:BP GO:0022618 protein-RNA complex assembly 1 208 1.0000000
GO:BP GO:0008150 biological_process 1 12110 1.0000000
GO:BP GO:0008152 metabolic process 1 8593 1.0000000
GO:BP GO:0001649 osteoblast differentiation 1 179 1.0000000
GO:BP GO:0001568 blood vessel development 1 537 1.0000000
GO:BP GO:0001503 ossification 1 317 1.0000000
GO:BP GO:0061458 reproductive system development 1 217 1.0000000
GO:BP GO:0048514 blood vessel morphogenesis 1 461 1.0000000
GO:BP GO:0000244 spliceosomal tri-snRNP complex assembly 2 21 1.0000000
GO:BP GO:0048608 reproductive structure development 1 214 1.0000000
GO:BP GO:0050670 regulation of lymphocyte proliferation 1 125 1.0000000
GO:BP GO:0000387 spliceosomal snRNP assembly 1 47 1.0000000
GO:BP GO:0044282 small molecule catabolic process 2 270 1.0000000
GO:BP GO:0045291 mRNA trans splicing, SL addition 1 7 1.0000000
KEGG KEGG:05168 Herpes simplex virus 1 infection 19 414 0.0289451
KEGG KEGG:04144 Endocytosis 13 232 0.1966195
KEGG KEGG:05031 Amphetamine addiction 3 49 0.2014024
KEGG KEGG:00900 Terpenoid backbone biosynthesis 1 21 0.2014024
KEGG KEGG:03250 Viral life cycle - HIV-1 5 56 0.2014024
KEGG KEGG:04213 Longevity regulating pathway - multiple species 4 55 0.2014024
KEGG KEGG:03015 mRNA surveillance pathway 5 87 0.2014024
KEGG KEGG:04146 Peroxisome 1 68 0.3673096
KEGG KEGG:04218 Cellular senescence 5 145 0.3673096
KEGG KEGG:00565 Ether lipid metabolism 3 28 0.3673096
KEGG KEGG:04924 Renin secretion 2 50 0.3673096
KEGG KEGG:03013 Nucleocytoplasmic transport 5 99 0.3754923
KEGG KEGG:04710 Circadian rhythm 2 30 0.3754923
KEGG KEGG:05166 Human T-cell leukemia virus 1 infection 5 180 0.3754923
KEGG KEGG:05212 Pancreatic cancer 5 75 0.4828849
KEGG KEGG:04666 Fc gamma R-mediated phagocytosis 1 75 0.4828849
KEGG KEGG:04022 cGMP-PKG signaling pathway 3 133 0.4828849
KEGG KEGG:03060 Protein export 2 23 0.4828849
KEGG KEGG:00970 Aminoacyl-tRNA biosynthesis 3 44 0.4828849
KEGG KEGG:05016 Huntington disease 4 256 0.4828849
KEGG KEGG:04330 Notch signaling pathway 1 51 0.4828849
KEGG KEGG:04110 Cell cycle 5 151 0.4828849
KEGG KEGG:00563 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 1 25 0.4828849
KEGG KEGG:05034 Alcoholism 3 117 0.4828849
KEGG KEGG:03020 RNA polymerase 3 34 0.4828849
KEGG KEGG:00564 Glycerophospholipid metabolism 1 76 0.4828849
KEGG KEGG:04720 Long-term potentiation 2 55 0.4828849
KEGG KEGG:05170 Human immunodeficiency virus 1 infection 6 165 0.4828849
KEGG KEGG:05220 Chronic myeloid leukemia 1 75 0.4977706
KEGG KEGG:04115 p53 signaling pathway 2 65 0.5110305
KEGG KEGG:04910 Insulin signaling pathway 4 121 0.5110305
KEGG KEGG:00310 Lysine degradation 2 59 0.5110305
KEGG KEGG:05132 Salmonella infection 1 214 0.5114731
KEGG KEGG:04921 Oxytocin signaling pathway 3 115 0.5229332
KEGG KEGG:04211 Longevity regulating pathway 3 78 0.5229332
KEGG KEGG:03450 Non-homologous end-joining 1 12 0.5229332
KEGG KEGG:04120 Ubiquitin mediated proteolysis 4 134 0.5229332
KEGG KEGG:04024 cAMP signaling pathway 3 151 0.5229332
KEGG KEGG:05418 Fluid shear stress and atherosclerosis 4 114 0.5229332
KEGG KEGG:05210 Colorectal cancer 4 84 0.5261649
KEGG KEGG:04922 Glucagon signaling pathway 2 84 0.5261649
KEGG KEGG:04923 Regulation of lipolysis in adipocytes 1 41 0.5261649
KEGG KEGG:04931 Insulin resistance 3 95 0.5261649
KEGG KEGG:04660 T cell receptor signaling pathway 3 70 0.5261649
KEGG KEGG:04613 Neutrophil extracellular trap formation 1 105 0.5261649
KEGG KEGG:04961 Endocrine and other factor-regulated calcium reabsorption 1 41 0.5261649
KEGG KEGG:05030 Cocaine addiction 1 35 0.5261649
KEGG KEGG:00770 Pantothenate and CoA biosynthesis 1 15 0.5261649
KEGG KEGG:05167 Kaposi sarcoma-associated herpesvirus infection 3 145 0.5261649
KEGG KEGG:05164 Influenza A 3 103 0.5261649
KEGG KEGG:05163 Human cytomegalovirus infection 5 176 0.5261649
KEGG KEGG:00983 Drug metabolism - other enzymes 2 44 0.5261649
KEGG KEGG:04140 Autophagy - animal 5 133 0.5261649
KEGG KEGG:04114 Oocyte meiosis 2 108 0.5261649
KEGG KEGG:03008 Ribosome biogenesis in eukaryotes 3 75 0.5261649
KEGG KEGG:05202 Transcriptional misregulation in cancer 1 128 0.5261649
KEGG KEGG:05169 Epstein-Barr virus infection 3 152 0.5261649
KEGG KEGG:04215 Apoptosis - multiple species 2 30 0.5261649
KEGG KEGG:05203 Viral carcinogenesis 1 165 0.5261649
KEGG KEGG:05225 Hepatocellular carcinoma 6 145 0.5261649
KEGG KEGG:04152 AMPK signaling pathway 3 103 0.5261649
KEGG KEGG:04370 VEGF signaling pathway 2 49 0.5261649
KEGG KEGG:05410 Hypertrophic cardiomyopathy 2 73 0.5261649
KEGG KEGG:05412 Arrhythmogenic right ventricular cardiomyopathy 1 63 0.5261649
KEGG KEGG:00562 Inositol phosphate metabolism 3 66 0.5261649
KEGG KEGG:04145 Phagosome 1 99 0.5261649
KEGG KEGG:05414 Dilated cardiomyopathy 1 78 0.5261649
KEGG KEGG:04728 Dopaminergic synapse 2 102 0.5261649
KEGG KEGG:04919 Thyroid hormone signaling pathway 1 112 0.5261649
KEGG KEGG:05221 Acute myeloid leukemia 3 56 0.5261649
KEGG KEGG:05032 Morphine addiction 1 56 0.5264123
KEGG KEGG:04071 Sphingolipid signaling pathway 3 107 0.5593040
KEGG KEGG:04664 Fc epsilon RI signaling pathway 2 46 0.5715765
KEGG KEGG:05162 Measles 2 97 0.6019181
KEGG KEGG:05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 1 69 0.6019181
KEGG KEGG:04210 Apoptosis 1 118 0.6019181
KEGG KEGG:04070 Phosphatidylinositol signaling system 1 91 0.6019181
KEGG KEGG:04721 Synaptic vesicle cycle 1 51 0.6019181
KEGG KEGG:05219 Bladder cancer 1 37 0.6019181
KEGG KEGG:00480 Glutathione metabolism 1 44 0.6019181
KEGG KEGG:04662 B cell receptor signaling pathway 1 56 0.6019181
KEGG KEGG:04658 Th1 and Th2 cell differentiation 1 53 0.6019181
KEGG KEGG:05135 Yersinia infection 3 112 0.6019181
KEGG KEGG:03010 Ribosome 1 127 0.6019181
KEGG KEGG:04150 mTOR signaling pathway 3 135 0.6056535
KEGG KEGG:01524 Platinum drug resistance 1 65 0.6056535
KEGG KEGG:05204 Chemical carcinogenesis - DNA adducts 1 23 0.6056535
KEGG KEGG:04625 C-type lectin receptor signaling pathway 1 76 0.6056535
KEGG KEGG:00982 Drug metabolism - cytochrome P450 1 21 0.6056535
KEGG KEGG:04659 Th17 cell differentiation 1 64 0.6056535
KEGG KEGG:01522 Endocrine resistance 2 85 0.6056535
KEGG KEGG:05206 MicroRNAs in cancer 1 149 0.6056535
KEGG KEGG:04350 TGF-beta signaling pathway 2 84 0.6056535
KEGG KEGG:05165 Human papillomavirus infection 1 272 0.6056535
KEGG KEGG:03022 Basal transcription factors 2 40 0.6056535
KEGG KEGG:04936 Alcoholic liver disease 3 97 0.6056535
KEGG KEGG:03050 Proteasome 2 42 0.6056535
KEGG KEGG:05160 Hepatitis C 2 114 0.6056535
KEGG KEGG:04012 ErbB signaling pathway 2 78 0.6056535
KEGG KEGG:04724 Glutamatergic synapse 1 74 0.6056535
KEGG KEGG:04014 Ras signaling pathway 3 171 0.6056535
KEGG KEGG:00980 Metabolism of xenobiotics by cytochrome P450 1 26 0.6134512
KEGG KEGG:04136 Autophagy - other 1 31 0.6159664
KEGG KEGG:04380 Osteoclast differentiation 1 87 0.6233804
KEGG KEGG:04650 Natural killer cell mediated cytotoxicity 1 63 0.6233804
KEGG KEGG:05231 Choline metabolism in cancer 2 84 0.6236130
KEGG KEGG:03420 Nucleotide excision repair 1 43 0.6276084
KEGG KEGG:04010 MAPK signaling pathway 2 240 0.6369039
KEGG KEGG:04530 Tight junction 2 137 0.6369039
KEGG KEGG:04310 Wnt signaling pathway 5 139 0.6421610
KEGG KEGG:03460 Fanconi anemia pathway 1 49 0.6421610
KEGG KEGG:05215 Prostate cancer 1 86 0.6421610
KEGG KEGG:04137 Mitophagy - animal 1 70 0.6421610
KEGG KEGG:05218 Melanoma 1 58 0.6421610
KEGG KEGG:04750 Inflammatory mediator regulation of TRP channels 1 72 0.6421610
KEGG KEGG:04623 Cytosolic DNA-sensing pathway 1 41 0.6421610
KEGG KEGG:04722 Neurotrophin signaling pathway 1 110 0.6421610
KEGG KEGG:05214 Glioma 1 67 0.6421610
KEGG KEGG:05223 Non-small cell lung cancer 1 67 0.6421610
KEGG KEGG:04620 Toll-like receptor signaling pathway 2 60 0.6421610
KEGG KEGG:04622 RIG-I-like receptor signaling pathway 1 48 0.6421610
KEGG KEGG:04920 Adipocytokine signaling pathway 1 51 0.6451022
KEGG KEGG:04914 Progesterone-mediated oocyte maturation 3 86 0.6451022
KEGG KEGG:05200 Pathways in cancer 1 409 0.6531345
KEGG KEGG:05417 Lipid and atherosclerosis 2 153 0.6531345
KEGG KEGG:04913 Ovarian steroidogenesis 1 28 0.6531345
KEGG KEGG:03040 Spliceosome 4 132 0.6531345
KEGG KEGG:05152 Tuberculosis 1 106 0.6620791
KEGG KEGG:04714 Thermogenesis 6 195 0.6620791
KEGG KEGG:04392 Hippo signaling pathway - multiple species 1 26 0.6671480
KEGG KEGG:04360 Axon guidance 1 162 0.6671480
KEGG KEGG:04340 Hedgehog signaling pathway 1 50 0.6765000
KEGG KEGG:04657 IL-17 signaling pathway 1 56 0.6765000
KEGG KEGG:05222 Small cell lung cancer 1 87 0.6765000
KEGG KEGG:04611 Platelet activation 1 89 0.6783915
KEGG KEGG:04217 Necroptosis 3 108 0.6783915
KEGG KEGG:04371 Apelin signaling pathway 2 106 0.6783915
KEGG KEGG:05416 Viral myocarditis 1 40 0.6783915
KEGG KEGG:04141 Protein processing in endoplasmic reticulum 4 161 0.6783915
KEGG KEGG:00140 Steroid hormone biosynthesis 1 19 0.6783915
KEGG KEGG:04270 Vascular smooth muscle contraction 1 94 0.6783915
KEGG KEGG:04933 AGE-RAGE signaling pathway in diabetic complications 1 91 0.6783915
KEGG KEGG:05017 Spinocerebellar ataxia 1 124 0.6783915
KEGG KEGG:00600 Sphingolipid metabolism 1 44 0.6783915
KEGG KEGG:05161 Hepatitis B 3 135 0.6783915
KEGG KEGG:04630 JAK-STAT signaling pathway 3 88 0.6806920
KEGG KEGG:05224 Breast cancer 2 117 0.6811029
KEGG KEGG:04020 Calcium signaling pathway 1 157 0.7187221
KEGG KEGG:04261 Adrenergic signaling in cardiomyocytes 1 128 0.7207243
KEGG KEGG:04390 Hippo signaling pathway 1 135 0.7250995
KEGG KEGG:05216 Thyroid cancer 1 35 0.7296060
KEGG KEGG:05131 Shigellosis 3 210 0.7403762
KEGG KEGG:04520 Adherens junction 1 67 0.7416960
KEGG KEGG:05020 Prion disease 1 220 0.7416960
KEGG KEGG:05134 Legionellosis 1 39 0.7416960
KEGG KEGG:04080 Neuroactive ligand-receptor interaction 1 108 0.7416960
KEGG KEGG:05022 Pathways of neurodegeneration - multiple diseases 2 386 0.7499097
KEGG KEGG:01521 EGFR tyrosine kinase inhibitor resistance 1 74 0.7514838
KEGG KEGG:04151 PI3K-Akt signaling pathway 4 254 0.7540450
KEGG KEGG:00000 KEGG root term 2 5553 0.7540450
KEGG KEGG:04934 Cushing syndrome 1 121 0.7540450
KEGG KEGG:04068 FoxO signaling pathway 1 110 0.7540450
KEGG KEGG:05014 Amyotrophic lateral sclerosis 8 303 0.7540450
KEGG KEGG:01240 Biosynthesis of cofactors 2 115 0.7540450
KEGG KEGG:00520 Amino sugar and nucleotide sugar metabolism 1 46 0.7540450
KEGG KEGG:04510 Focal adhesion 1 177 0.7540450
KEGG KEGG:00830 Retinol metabolism 1 16 0.7540450
KEGG KEGG:05321 Inflammatory bowel disease 1 22 0.7540450
KEGG KEGG:05415 Diabetic cardiomyopathy 1 169 0.7540450
KEGG KEGG:05205 Proteoglycans in cancer 1 170 0.7540450
KEGG KEGG:04932 Non-alcoholic fatty liver disease 1 131 0.7858286
KEGG KEGG:04810 Regulation of actin cytoskeleton 1 179 0.7885689
KEGG KEGG:05010 Alzheimer disease 1 316 0.7988949
KEGG KEGG:04912 GnRH signaling pathway 1 76 0.7988949
KEGG KEGG:05213 Endometrial cancer 1 57 0.7988949
KEGG KEGG:05100 Bacterial invasion of epithelial cells 1 74 0.7988949
KEGG KEGG:04621 NOD-like receptor signaling pathway 1 117 0.7988949
KEGG KEGG:00230 Purine metabolism 2 97 0.7988949
KEGG KEGG:04066 HIF-1 signaling pathway 1 89 0.7988949
KEGG KEGG:04064 NF-kappa B signaling pathway 1 70 0.8003798
KEGG KEGG:01232 Nucleotide metabolism 1 69 0.8005728
KEGG KEGG:05217 Basal cell carcinoma 1 49 0.8156826
KEGG KEGG:04668 TNF signaling pathway 1 87 0.8301102
KEGG KEGG:05171 Coronavirus disease - COVID-19 1 161 0.8494962
KEGG KEGG:03320 PPAR signaling pathway 1 50 0.8631254
KEGG KEGG:04926 Relaxin signaling pathway 1 104 0.8631254
KEGG KEGG:05226 Gastric cancer 1 117 0.8690913
KEGG KEGG:04142 Lysosome 1 118 0.8721967
KEGG KEGG:01100 Metabolic pathways 3 1147 0.8775155
KEGG KEGG:05146 Amoebiasis 1 64 0.8931225
KEGG KEGG:04062 Chemokine signaling pathway 1 113 0.9362021
KEGG KEGG:05207 Chemical carcinogenesis - receptor activation 1 142 0.9428573
KEGG KEGG:04015 Rap1 signaling pathway 1 164 0.9431059
KEGG KEGG:05012 Parkinson disease 2 226 0.9431059
KEGG KEGG:05130 Pathogenic Escherichia coli infection 2 150 0.9431059
KEGG KEGG:04550 Signaling pathways regulating pluripotency of stem cells 1 104 0.9494064
KEGG KEGG:05208 Chemical carcinogenesis - reactive oxygen species 1 186 0.9494064
KEGG KEGG:04072 Phospholipase D signaling pathway 1 110 0.9773988

B set

# SETB_resgenes <- gost(query = intersect_genes$ENTREZID,
#                     organism = "hsapiens",
#                     significant = FALSE,
#                     ordered_query = TRUE,
#                     domain_scope = "custom",
#                     measure_underrepresentation = FALSE,
#                     evcodes = FALSE,
#                     user_threshold = 0.05,
#                     correction_method = c("fdr"),
#                     custom_bg = EPI508_list$ENTREZID,
#                     sources=c("KEGG"))
# saveRDS(SETB_resgenes,"data/DEG-GO/SETB_resgenes.RDS")
# SETB_resgenes <- readRDS("data/DEG-GO/SETB_resgenes.RDS")
# 
# Set_B_genes <- gostplot(SETB_resgenes, capped = FALSE, interactive = TRUE)
# Set_B_genes
# 
# setB_table <- SETB_resgenes$result %>% 
#   dplyr::select(c(source, term_id,
#                   term_name,intersection_size, 
#                    term_size, p_value))# %>% 
# 
# # list_intersect_path <- KEGG_05168 %>% 
# #   filter(Symbol%in% intersect_genes$SYMBOL) 
# 
# setB_table%>% 
#   kable(., caption = "No enrichment with this small background of KEGG pathway") %>%
#   kable_paper("striped", full_width = FALSE) %>%
#   kable_styling(
#     full_width = FALSE,
#     position = "left",
#     bootstrap_options = c("striped", "hover")
#   ) %>%
#   scroll_box(width = "100%", height = "400px")