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Last updated: 2019-10-28

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Knit directory: fgf_alldata/

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    Modified:   analysis/10_wc_pseudobulk.Rmd
    Modified:   analysis/11_wc_astro_wgcna.Rmd
    Modified:   analysis/12_oligo_labeltransfer.Rmd
    Modified:   analysis/14_tanycyte_labeltransfer.Rmd
    Modified:   analysis/15_tany_wgcna_pseudo.Rmd
    Modified:   analysis/3_neuron_dge_analysis.Rmd
    Modified:   analysis/7_ventricular_wgcna.Rmd
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File	Version	Author	Date	Message
Rmd	8ab4106	Full Name	2019-10-28	wflow_publish(“analysis/index.Rmd”)
Rmd	749ac66	dylanmr	2019-10-21	Start workflowr project.

Project overview

A single ICV injection of FGF1 induces permanent normalization of blood glucose levels in multiple models of type 2 diabetes. To understand the effects of FGF1 and identify cell-type specific responses key to blood glucose normalization, we performed multiple high throughput transcriptomic analyses at different timepoints in cohorts of male ob/ob mice.

Experimental Design

All the results and plots presented in the pages below should be reproduceible on your computer.

These are the results of analyses of neuronal populations in snRNA-seq data.

These are the results of my analyses of glial cells from snRNA-seq data.

These are the results of my whole cell analyses.