Last updated: 2022-04-27

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Knit directory: logistic-susie-gsea/

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This website documents the development of sparse multiple regression methods for gene set enrichment analysis (GSEA), as well as analysis demonstrating their utility in comparison to typical marginal (one gene set at a time) GSEA techniques. Additionally we provide exposition on GSEA, a review of existing tools for GSEA, and related problems and the ideas motivating the development of these new methods.

Simulations

Analysis

[GSEA should be done jointly, not marginally]

Logistic SuSiE GSEA examples

Wenhe’s Baboom Diet Example

Kenneths Human/Chimp EBs

GSEA from summary statistics

Deng NMF/SNMF