Last updated: 2023-07-28

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Knit directory: Cardiotoxicity/

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File Version Author Date Message
Rmd fdb94fb reneeisnowhere 2023-07-28 new figures update
Rmd 62286c3 reneeisnowhere 2023-07-28 Updateing figure code
html 680af3a reneeisnowhere 2023-06-26 Build site.
Rmd d7b9ff1 reneeisnowhere 2023-06-26 Adding supplementary figures
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Rmd 2b109c3 reneeisnowhere 2023-06-23 adding some supp graphs
Rmd c1d667f reneeisnowhere 2023-06-23 updating the codes at Friday start.

library(tidyverse)
library(ggpubr)
library(rstatix)
library(zoo)
library(ggsignif)
library(RColorBrewer)

library(ComplexHeatmap)
library(gridExtra)
library(cowplot)
library(drc)

Fig. S1

ctnnt <- read.csv("data/ctnnt_results.txt", row.names = 1)
ctnnt %>% 
  mutate(Individual=fct_inorder(Individual)) %>% 
  ggplot(., aes(Individual,Percent , fill=Individual))+
  geom_boxplot()+
  geom_point()+
  geom_hline(yintercept =70,linetype="dashed", alpha=0.75)+###adds a line indicating high positivity +
coord_cartesian(ylim = c(0,105))+ ##set those limits
  theme_bw()+  ##white background
  labs(title="Cardiomyocyte Purity")+ #subtitle = "from  n>3 differentiations")+
  geom_boxplot(color="black",alpha =0.2, fill=NA, fatten=0, show.legend = FALSE)+
  scale_fill_brewer(palette = "Dark2",name="" )+
  xlab(NULL)+ 
  ylab("% cTNNT+ ")+
  guides(fill = NULL)+
  theme(plot.title = element_text(hjust = 0.5, size =20, face= "bold"), 
        axis.title.x=element_blank(),
        axis.text.x=element_blank(),###removes all axis names and tick names etc.####
        axis.ticks.x=element_blank(),
        # legend.text=element_text(size=15), 
        axis.title.y=element_text(size=15),
        axis.ticks.y=element_line(size =2),
        axis.text.y=element_text(size=10, face = "bold"),
       panel.grid.major = element_line(colour = 'grey'),
       panel.border=element_rect(fill = NA, size = 3),
       plot.subtitle=element_text(size=18, hjust=0.5, face="italic", color="black")) 

# ctnnt %>%
#   summary() %>% 
#   kable(., caption= "Stats summary of cTNNT+ FACs readings") %>% 
#   kable_paper("striped", full_width = FALSE) %>%  
#   kable_styling(full_width = FALSE,font_size = 18) #%>% 
#   # scroll_box(width = "60%", height = "400px")

Fig. S2

drug_pal_fact <- c("#8B006D","#DF707E","#F1B72B", "#3386DD","#707031","#41B333")
library(data.table)
conf_int <- readRDS("data/plot_intv_list.RDS")
DRC_list <- readRDS("data/plot_list_DRC.RDS")
pull_drc2 <- data.frame("ind1", "ind2","ind3","ind4","ind5","ind6")
doubl_plot <- data.frame("ind3a", "ind3b", "ind5a", "ind5b")
lvl_order <- c('1','2','3','4','5','6')
intervals <- rbindlist(conf_int,idcol="trt")
drug_list <- c("DNR","DOX","EPI","MTX", "TRZ", "VEH")
GeomRibbon$handle_na <- function(data, params) {  data }
intervals %>% 
  separate("trt", into=c("sDrug",NA))
     sDrug  indv    Prediction         Lower      Upper  Conc
1      DNR ind1a  0.9864402141  0.9643502991 1.00853013  0.01
2      DNR ind1a  0.9864402141  0.9643502991 1.00853013  0.01
3      DNR ind1a  0.9864402141  0.9643502991 1.00853013  0.01
4      DNR ind1a  0.9864402141  0.9643502991 1.00853013  0.01
5      DNR ind1a  0.9406247584  0.8824471938 0.99880232  0.05
6      DNR ind1a  0.9406247584  0.8824471938 0.99880232  0.05
7      DNR ind1a  0.9406247584  0.8824471938 0.99880232  0.05
8      DNR ind1a  0.9406247584  0.8824471938 0.99880232  0.05
9      DNR ind1a  0.8913577833  0.8146392200 0.96807635  0.10
10     DNR ind1a  0.8913577833  0.8146392200 0.96807635  0.10
11     DNR ind1a  0.8913577833  0.8146392200 0.96807635  0.10
12     DNR ind1a  0.8913577833  0.8146392200 0.96807635  0.10
13     DNR ind1a  0.6375493321  0.5577718330 0.71732683  0.50
14     DNR ind1a  0.6375493321  0.5577718330 0.71732683  0.50
15     DNR ind1a  0.6375493321  0.5577718330 0.71732683  0.50
16     DNR ind1a  0.6375493321  0.5577718330 0.71732683  0.50
17     DNR ind1a  0.4719933063  0.3889806275 0.55500599  1.00
18     DNR ind1a  0.4719933063  0.3889806275 0.55500599  1.00
19     DNR ind1a  0.4719933063  0.3889806275 0.55500599  1.00
20     DNR ind1a  0.4719933063  0.3889806275 0.55500599  1.00
21     DNR ind1a  0.1407807999  0.0594057146 0.22215589  5.00
22     DNR ind1a  0.1407807999  0.0594057146 0.22215589  5.00
23     DNR ind1a  0.1407807999  0.0594057146 0.22215589  5.00
24     DNR ind1a  0.1407807999  0.0594057146 0.22215589  5.00
25     DNR ind1a  0.0617921949 -0.0083686605 0.13195305 10.00
26     DNR ind1a  0.0617921949 -0.0083686605 0.13195305 10.00
27     DNR ind1a  0.0617921949 -0.0083686605 0.13195305 10.00
28     DNR ind1a  0.0617921949 -0.0083686605 0.13195305 10.00
29     DNR ind1a -0.0171190559 -0.1217349941 0.08749688 50.00
30     DNR ind1a -0.0171190559 -0.1217349941 0.08749688 50.00
31     DNR ind1a -0.0171190559 -0.1217349941 0.08749688 50.00
32     DNR ind1a -0.0171190559 -0.1217349941 0.08749688 50.00
33     DNR ind1b  0.9789072369  0.9328531335 1.02496134  0.01
34     DNR ind1b  0.9789072369  0.9328531335 1.02496134  0.01
35     DNR ind1b  0.9789072369  0.9328531335 1.02496134  0.01
36     DNR ind1b  0.9789072369  0.9328531335 1.02496134  0.01
37     DNR ind1b  0.9207648004  0.8177009527 1.02382865  0.05
38     DNR ind1b  0.9207648004  0.8177009527 1.02382865  0.05
39     DNR ind1b  0.9207648004  0.8177009527 1.02382865  0.05
40     DNR ind1b  0.9207648004  0.8177009527 1.02382865  0.05
41     DNR ind1b  0.8648079949  0.7357654673 0.99385052  0.10
42     DNR ind1b  0.8648079949  0.7357654673 0.99385052  0.10
43     DNR ind1b  0.8648079949  0.7357654673 0.99385052  0.10
44     DNR ind1b  0.6142747348  0.4496956725 0.77885380  0.50
45     DNR ind1b  0.6142747348  0.4496956725 0.77885380  0.50
46     DNR ind1b  0.6142747348  0.4496956725 0.77885380  0.50
47     DNR ind1b  0.6142747348  0.4496956725 0.77885380  0.50
48     DNR ind1b  0.4655592950  0.2848842049 0.64623439  1.00
49     DNR ind1b  0.4655592950  0.2848842049 0.64623439  1.00
50     DNR ind1b  0.4655592950  0.2848842049 0.64623439  1.00
51     DNR ind1b  0.4655592950  0.2848842049 0.64623439  1.00
52     DNR ind1b  0.1719318974  0.0234700602 0.32039373  5.00
53     DNR ind1b  0.1719318974  0.0234700602 0.32039373  5.00
54     DNR ind1b  0.1719318974  0.0234700602 0.32039373  5.00
55     DNR ind1b  0.1719318974  0.0234700602 0.32039373  5.00
56     DNR ind1b  0.0974762137 -0.0459788929 0.24093132 10.00
57     DNR ind1b  0.0974762137 -0.0459788929 0.24093132 10.00
58     DNR ind1b  0.0974762137 -0.0459788929 0.24093132 10.00
59     DNR ind1b  0.0974762137 -0.0459788929 0.24093132 10.00
60     DNR ind1b  0.0161126988 -0.2027753431 0.23500074 50.00
61     DNR ind1b  0.0161126988 -0.2027753431 0.23500074 50.00
62     DNR ind1b  0.0161126988 -0.2027753431 0.23500074 50.00
63     DNR ind1b  0.0161126988 -0.2027753431 0.23500074 50.00
64     DNR ind2a  0.9941295661  0.9760187244 1.01224041  0.01
65     DNR ind2a  0.9941295661  0.9760187244 1.01224041  0.01
66     DNR ind2a  0.9941295661  0.9760187244 1.01224041  0.01
67     DNR ind2a  0.9941295661  0.9760187244 1.01224041  0.01
68     DNR ind2a  0.9719293545  0.9135159344 1.03034277  0.05
69     DNR ind2a  0.9719293545  0.9135159344 1.03034277  0.05
70     DNR ind2a  0.9719293545  0.9135159344 1.03034277  0.05
71     DNR ind2a  0.9719293545  0.9135159344 1.03034277  0.05
72     DNR ind2a  0.9457940347  0.8567952007 1.03479287  0.10
73     DNR ind2a  0.9457940347  0.8567952007 1.03479287  0.10
74     DNR ind2a  0.9457940347  0.8567952007 1.03479287  0.10
75     DNR ind2a  0.9457940347  0.8567952007 1.03479287  0.10
76     DNR ind2a  0.7779053723  0.6292189611 0.92659178  0.50
77     DNR ind2a  0.7779053723  0.6292189611 0.92659178  0.50
78     DNR ind2a  0.7779053723  0.6292189611 0.92659178  0.50
79     DNR ind2a  0.7779053723  0.6292189611 0.92659178  0.50
80     DNR ind2a  0.6329726000  0.5010942160 0.76485098  1.00
81     DNR ind2a  0.6329726000  0.5010942160 0.76485098  1.00
82     DNR ind2a  0.6329726000  0.5010942160 0.76485098  1.00
83     DNR ind2a  0.6329726000  0.5010942160 0.76485098  1.00
84     DNR ind2a  0.2193731987  0.0953438692 0.34340253  5.00
85     DNR ind2a  0.2193731987  0.0953438692 0.34340253  5.00
86     DNR ind2a  0.2193731987  0.0953438692 0.34340253  5.00
87     DNR ind2a  0.2193731987  0.0953438692 0.34340253  5.00
88     DNR ind2a  0.0884010134 -0.0252050465 0.20200707 10.00
89     DNR ind2a  0.0884010134 -0.0252050465 0.20200707 10.00
90     DNR ind2a  0.0884010134 -0.0252050465 0.20200707 10.00
91     DNR ind2a  0.0884010134 -0.0252050465 0.20200707 10.00
92     DNR ind2a -0.0553611563 -0.2025784388 0.09185613 50.00
93     DNR ind2a -0.0553611563 -0.2025784388 0.09185613 50.00
94     DNR ind2a -0.0553611563 -0.2025784388 0.09185613 50.00
95     DNR ind2a -0.0553611563 -0.2025784388 0.09185613 50.00
96     DNR ind2b  1.0000000000           NaN        NaN  0.01
97     DNR ind2b  1.0000000000           NaN        NaN  0.01
98     DNR ind2b  1.0000000000           NaN        NaN  0.01
99     DNR ind2b  1.0000000000           NaN        NaN  0.01
100    DNR ind2b  1.0000000000           NaN        NaN  0.05
101    DNR ind2b  1.0000000000           NaN        NaN  0.05
102    DNR ind2b  1.0000000000           NaN        NaN  0.05
103    DNR ind2b  1.0000000000           NaN        NaN  0.05
104    DNR ind2b  1.0000000000           NaN        NaN  0.10
105    DNR ind2b  1.0000000000           NaN        NaN  0.10
106    DNR ind2b  1.0000000000           NaN        NaN  0.10
107    DNR ind2b  1.0000000000           NaN        NaN  0.10
108    DNR ind2b  0.9999999965           NaN        NaN  0.50
109    DNR ind2b  0.9999999965           NaN        NaN  0.50
110    DNR ind2b  0.9999999965           NaN        NaN  0.50
111    DNR ind2b  0.9999999965           NaN        NaN  0.50
112    DNR ind2b  0.9999980043           NaN        NaN  1.00
113    DNR ind2b  0.9999980043           NaN        NaN  1.00
114    DNR ind2b  0.9999980043           NaN        NaN  1.00
115    DNR ind2b  0.9999980043           NaN        NaN  1.00
116    DNR ind2b  0.1687857523 -0.0568678967 0.39443940  5.00
117    DNR ind2b  0.1687857523 -0.0568678967 0.39443940  5.00
118    DNR ind2b  0.1687857523 -0.0568678967 0.39443940  5.00
119    DNR ind2b  0.1687857523 -0.0568678967 0.39443940  5.00
120    DNR ind2b  0.0045050457 -0.1537968928 0.16280698 10.00
121    DNR ind2b  0.0045050457 -0.1537968928 0.16280698 10.00
122    DNR ind2b  0.0045050457 -0.1537968928 0.16280698 10.00
123    DNR ind2b  0.0045050457 -0.1537968928 0.16280698 10.00
124    DNR ind2b  0.0041599598 -0.1544905964 0.16281052 50.00
125    DNR ind2b  0.0041599598 -0.1544905964 0.16281052 50.00
126    DNR ind2b  0.0041599598 -0.1544905964 0.16281052 50.00
127    DNR ind2b  0.0041599598 -0.1544905964 0.16281052 50.00
128    DNR ind3a  0.9999455171  0.9996082798 1.00028275  0.01
129    DNR ind3a  0.9999455171  0.9996082798 1.00028275  0.01
130    DNR ind3a  0.9999455171  0.9996082798 1.00028275  0.01
131    DNR ind3a  0.9999455171  0.9996082798 1.00028275  0.01
132    DNR ind3a  0.9972527896  0.9870196764 1.00748590  0.05
133    DNR ind3a  0.9972527896  0.9870196764 1.00748590  0.05
134    DNR ind3a  0.9972527896  0.9870196764 1.00748590  0.05
135    DNR ind3a  0.9972527896  0.9870196764 1.00748590  0.05
136    DNR ind3a  0.9853118334  0.9464309063 1.02419276  0.10
137    DNR ind3a  0.9853118334  0.9464309063 1.02419276  0.10
138    DNR ind3a  0.9853118334  0.9464309063 1.02419276  0.10
139    DNR ind3a  0.9853118334  0.9464309063 1.02419276  0.10
140    DNR ind3a  0.5876357877  0.4506894072 0.72458217  0.50
141    DNR ind3a  0.5876357877  0.4506894072 0.72458217  0.50
142    DNR ind3a  0.5876357877  0.4506894072 0.72458217  0.50
143    DNR ind3a  0.5876357877  0.4506894072 0.72458217  0.50
144    DNR ind3a  0.2565325984  0.1220397553 0.39102544  1.00
145    DNR ind3a  0.2565325984  0.1220397553 0.39102544  1.00
146    DNR ind3a  0.2565325984  0.1220397553 0.39102544  1.00
147    DNR ind3a  0.2565325984  0.1220397553 0.39102544  1.00
148    DNR ind3a  0.0953743361  0.0113243786 0.17942429  5.00
149    DNR ind3a  0.0953743361  0.0113243786 0.17942429  5.00
150    DNR ind3a  0.0953743361  0.0113243786 0.17942429  5.00
151    DNR ind3a  0.0953743361  0.0113243786 0.17942429  5.00
152    DNR ind3a  0.0921372786  0.0046130610 0.17966150 10.00
153    DNR ind3a  0.0921372786  0.0046130610 0.17966150 10.00
154    DNR ind3a  0.0921372786  0.0046130610 0.17966150 10.00
155    DNR ind3a  0.0921372786  0.0046130610 0.17966150 10.00
156    DNR ind3a  0.0914159254  0.0026774899 0.18015436 50.00
157    DNR ind3a  0.0914159254  0.0026774899 0.18015436 50.00
158    DNR ind3a  0.0914159254  0.0026774899 0.18015436 50.00
159    DNR ind3a  0.0914159254  0.0026774899 0.18015436 50.00
160    DNR ind3b  0.9886943231  0.9682565389 1.00913211  0.01
161    DNR ind3b  0.9886943231  0.9682565389 1.00913211  0.01
162    DNR ind3b  0.9886943231  0.9682565389 1.00913211  0.01
163    DNR ind3b  0.9886943231  0.9682565389 1.00913211  0.01
164    DNR ind3b  0.9441645810  0.8836010249 1.00472814  0.05
165    DNR ind3b  0.9441645810  0.8836010249 1.00472814  0.05
166    DNR ind3b  0.9441645810  0.8836010249 1.00472814  0.05
167    DNR ind3b  0.9441645810  0.8836010249 1.00472814  0.05
168    DNR ind3b  0.8928872443  0.8090343670 0.97674012  0.10
169    DNR ind3b  0.8928872443  0.8090343670 0.97674012  0.10
170    DNR ind3b  0.8928872443  0.8090343670 0.97674012  0.10
171    DNR ind3b  0.8928872443  0.8090343670 0.97674012  0.10
172    DNR ind3b  0.6181072978  0.5133474661 0.72286713  0.50
173    DNR ind3b  0.6181072978  0.5133474661 0.72286713  0.50
174    DNR ind3b  0.6181072978  0.5133474661 0.72286713  0.50
175    DNR ind3b  0.6181072978  0.5133474661 0.72286713  0.50
176    DNR ind3b  0.4450856434  0.3328114604 0.55735983  1.00
177    DNR ind3b  0.4450856434  0.3328114604 0.55735983  1.00
178    DNR ind3b  0.4450856434  0.3328114604 0.55735983  1.00
179    DNR ind3b  0.4450856434  0.3328114604 0.55735983  1.00
180    DNR ind3b  0.1397126437  0.0486266944 0.23079859  5.00
181    DNR ind3b  0.1397126437  0.0486266944 0.23079859  5.00
182    DNR ind3b  0.1397126437  0.0486266944 0.23079859  5.00
183    DNR ind3b  0.1397126437  0.0486266944 0.23079859  5.00
184    DNR ind3b  0.0780468716 -0.0111904067 0.16728415 10.00
185    DNR ind3b  0.0780468716 -0.0111904067 0.16728415 10.00
186    DNR ind3b  0.0780468716 -0.0111904067 0.16728415 10.00
187    DNR ind3b  0.0780468716 -0.0111904067 0.16728415 10.00
188    DNR ind3b  0.0231889711 -0.0995433009 0.14592124 50.00
189    DNR ind3b  0.0231889711 -0.0995433009 0.14592124 50.00
190    DNR ind3b  0.0231889711 -0.0995433009 0.14592124 50.00
191    DNR ind3b  0.0231889711 -0.0995433009 0.14592124 50.00
192    DNR ind4a  0.9944225044  0.9839932139 1.00485179  0.01
193    DNR ind4a  0.9944225044  0.9839932139 1.00485179  0.01
194    DNR ind4a  0.9944225044  0.9839932139 1.00485179  0.01
195    DNR ind4a  0.9944225044  0.9839932139 1.00485179  0.01
196    DNR ind4a  0.9607486420  0.9174705770 1.00402671  0.05
197    DNR ind4a  0.9607486420  0.9174705770 1.00402671  0.05
198    DNR ind4a  0.9607486420  0.9174705770 1.00402671  0.05
199    DNR ind4a  0.9607486420  0.9174705770 1.00402671  0.05
200    DNR ind4a  0.9123358915  0.8447910835 0.97988070  0.10
201    DNR ind4a  0.9123358915  0.8447910835 0.97988070  0.10
202    DNR ind4a  0.9123358915  0.8447910835 0.97988070  0.10
203    DNR ind4a  0.9123358915  0.8447910835 0.97988070  0.10
204    DNR ind4a  0.5881328671  0.5091261829 0.66713955  0.50
205    DNR ind4a  0.5881328671  0.5091261829 0.66713955  0.50
206    DNR ind4a  0.5881328671  0.5091261829 0.66713955  0.50
207    DNR ind4a  0.5881328671  0.5091261829 0.66713955  0.50
208    DNR ind4a  0.3775786361  0.2876920446 0.46746523  1.00
209    DNR ind4a  0.3775786361  0.2876920446 0.46746523  1.00
210    DNR ind4a  0.3775786361  0.2876920446 0.46746523  1.00
211    DNR ind4a  0.3775786361  0.2876920446 0.46746523  1.00
212    DNR ind4a  0.0761719981  0.0119444232 0.14039957  5.00
213    DNR ind4a  0.0761719981  0.0119444232 0.14039957  5.00
214    DNR ind4a  0.0761719981  0.0119444232 0.14039957  5.00
215    DNR ind4a  0.0761719981  0.0119444232 0.14039957  5.00
216    DNR ind4a  0.0333546538 -0.0309786595 0.09768797 10.00
217    DNR ind4a  0.0333546538 -0.0309786595 0.09768797 10.00
218    DNR ind4a  0.0333546538 -0.0309786595 0.09768797 10.00
219    DNR ind4a  0.0333546538 -0.0309786595 0.09768797 10.00
220    DNR ind4a  0.0038907399 -0.0794778497 0.08725933 50.00
221    DNR ind4a  0.0038907399 -0.0794778497 0.08725933 50.00
222    DNR ind4a  0.0038907399 -0.0794778497 0.08725933 50.00
223    DNR ind4a  0.0038907399 -0.0794778497 0.08725933 50.00
224    DNR ind4b  0.8460085265  0.7733084313 0.91870862  0.01
225    DNR ind4b  0.8460085265  0.7733084313 0.91870862  0.01
226    DNR ind4b  0.8460085265  0.7733084313 0.91870862  0.01
227    DNR ind4b  0.8460085265  0.7733084313 0.91870862  0.01
228    DNR ind4b  0.6843203523  0.6112839052 0.75735680  0.05
229    DNR ind4b  0.6843203523  0.6112839052 0.75735680  0.05
230    DNR ind4b  0.6843203523  0.6112839052 0.75735680  0.05
231    DNR ind4b  0.6843203523  0.6112839052 0.75735680  0.05
232    DNR ind4b  0.5898966409  0.5224043888 0.65738889  0.10
233    DNR ind4b  0.5898966409  0.5224043888 0.65738889  0.10
234    DNR ind4b  0.5898966409  0.5224043888 0.65738889  0.10
235    DNR ind4b  0.5898966409  0.5224043888 0.65738889  0.10
236    DNR ind4b  0.3452251620  0.2776669739 0.41278335  0.50
237    DNR ind4b  0.3452251620  0.2776669739 0.41278335  0.50
238    DNR ind4b  0.3452251620  0.2776669739 0.41278335  0.50
239    DNR ind4b  0.3452251620  0.2776669739 0.41278335  0.50
240    DNR ind4b  0.2466694609  0.1782681160 0.31507081  1.00
241    DNR ind4b  0.2466694609  0.1782681160 0.31507081  1.00
242    DNR ind4b  0.2466694609  0.1782681160 0.31507081  1.00
243    DNR ind4b  0.2466694609  0.1782681160 0.31507081  1.00
244    DNR ind4b  0.0722091030  0.0116290457 0.13278916  5.00
245    DNR ind4b  0.0722091030  0.0116290457 0.13278916  5.00
246    DNR ind4b  0.0722091030  0.0116290457 0.13278916  5.00
247    DNR ind4b  0.0722091030  0.0116290457 0.13278916  5.00
248    DNR ind4b  0.0225725187 -0.0416375287 0.08678257 10.00
249    DNR ind4b  0.0225725187 -0.0416375287 0.08678257 10.00
250    DNR ind4b  0.0225725187 -0.0416375287 0.08678257 10.00
251    DNR ind4b  0.0225725187 -0.0416375287 0.08678257 10.00
252    DNR ind4b -0.0474334557 -0.1398816021 0.04501469 50.00
253    DNR ind4b -0.0474334557 -0.1398816021 0.04501469 50.00
254    DNR ind4b -0.0474334557 -0.1398816021 0.04501469 50.00
255    DNR ind4b -0.0474334557 -0.1398816021 0.04501469 50.00
256    DNR ind5a  0.9729086936  0.9321070145 1.01371037  0.01
257    DNR ind5a  0.9729086936  0.9321070145 1.01371037  0.01
258    DNR ind5a  0.9729086936  0.9321070145 1.01371037  0.01
259    DNR ind5a  0.9729086936  0.9321070145 1.01371037  0.01
260    DNR ind5a  0.9150970698  0.8369432366 0.99325090  0.05
261    DNR ind5a  0.9150970698  0.8369432366 0.99325090  0.05
262    DNR ind5a  0.9150970698  0.8369432366 0.99325090  0.05
263    DNR ind5a  0.9150970698  0.8369432366 0.99325090  0.05
264    DNR ind5a  0.8648788433  0.7719802852 0.95777740  0.10
265    DNR ind5a  0.8648788433  0.7719802852 0.95777740  0.10
266    DNR ind5a  0.8648788433  0.7719802852 0.95777740  0.10
267    DNR ind5a  0.8648788433  0.7719802852 0.95777740  0.10
268    DNR ind5a  0.6522666282  0.5481188996 0.75641436  0.50
269    DNR ind5a  0.6522666282  0.5481188996 0.75641436  0.50
270    DNR ind5a  0.6522666282  0.5481188996 0.75641436  0.50
271    DNR ind5a  0.6522666282  0.5481188996 0.75641436  0.50
272    DNR ind5a  0.5210004842  0.4100059785 0.63199499  1.00
273    DNR ind5a  0.5210004842  0.4100059785 0.63199499  1.00
274    DNR ind5a  0.5210004842  0.4100059785 0.63199499  1.00
275    DNR ind5a  0.5210004842  0.4100059785 0.63199499  1.00
276    DNR ind5a  0.2144716097  0.1018996991 0.32704352  5.00
277    DNR ind5a  0.2144716097  0.1018996991 0.32704352  5.00
278    DNR ind5a  0.2144716097  0.1018996991 0.32704352  5.00
279    DNR ind5a  0.2144716097  0.1018996991 0.32704352  5.00
280    DNR ind5a  0.1159412065  0.0133627192 0.21851969 10.00
281    DNR ind5a  0.1159412065  0.0133627192 0.21851969 10.00
282    DNR ind5a  0.1159412065  0.0133627192 0.21851969 10.00
283    DNR ind5a  0.1159412065  0.0133627192 0.21851969 10.00
284    DNR ind5a -0.0157644864 -0.1764055561 0.14487658 50.00
285    DNR ind5a -0.0157644864 -0.1764055561 0.14487658 50.00
286    DNR ind5a -0.0157644864 -0.1764055561 0.14487658 50.00
287    DNR ind5a -0.0157644864 -0.1764055561 0.14487658 50.00
288    DNR ind5b  0.9976355968  0.9845079164 1.01076328  0.01
289    DNR ind5b  0.9976355968  0.9845079164 1.01076328  0.01
290    DNR ind5b  0.9976355968  0.9845079164 1.01076328  0.01
291    DNR ind5b  0.9770409327  0.8981410143 1.05594085  0.05
292    DNR ind5b  0.9770409327  0.8981410143 1.05594085  0.05
293    DNR ind5b  0.9770409327  0.8981410143 1.05594085  0.05
294    DNR ind5b  0.9770409327  0.8981410143 1.05594085  0.05
295    DNR ind5b  0.9405997781  0.7924547616 1.08874479  0.10
296    DNR ind5b  0.9405997781  0.7924547616 1.08874479  0.10
297    DNR ind5b  0.9405997781  0.7924547616 1.08874479  0.10
298    DNR ind5b  0.6123969936  0.4043832360 0.82041075  0.50
299    DNR ind5b  0.6123969936  0.4043832360 0.82041075  0.50
300    DNR ind5b  0.6123969936  0.4043832360 0.82041075  0.50
301    DNR ind5b  0.3654619350  0.1875733614 0.54335051  1.00
302    DNR ind5b  0.3654619350  0.1875733614 0.54335051  1.00
303    DNR ind5b  0.3654619350  0.1875733614 0.54335051  1.00
304    DNR ind5b  0.3654619350  0.1875733614 0.54335051  1.00
305    DNR ind5b  0.0387679981 -0.0965757503 0.17411175  5.00
306    DNR ind5b  0.0387679981 -0.0965757503 0.17411175  5.00
307    DNR ind5b  0.0387679981 -0.0965757503 0.17411175  5.00
308    DNR ind5b  0.0387679981 -0.0965757503 0.17411175  5.00
309    DNR ind5b  0.0026000721 -0.1265208541 0.13172100 10.00
310    DNR ind5b  0.0026000721 -0.1265208541 0.13172100 10.00
311    DNR ind5b  0.0026000721 -0.1265208541 0.13172100 10.00
312    DNR ind5b  0.0026000721 -0.1265208541 0.13172100 10.00
313    DNR ind5b -0.0178308627 -0.1716620703 0.13600034 50.00
314    DNR ind5b -0.0178308627 -0.1716620703 0.13600034 50.00
315    DNR ind5b -0.0178308627 -0.1716620703 0.13600034 50.00
316    DNR ind5b -0.0178308627 -0.1716620703 0.13600034 50.00
317    DNR ind6a  0.9804185207  0.9427640171 1.01807302  0.01
318    DNR ind6a  0.9804185207  0.9427640171 1.01807302  0.01
319    DNR ind6a  0.9804185207  0.9427640171 1.01807302  0.01
320    DNR ind6a  0.9804185207  0.9427640171 1.01807302  0.01
321    DNR ind6a  0.9288424546  0.8425628994 1.01512201  0.05
322    DNR ind6a  0.9288424546  0.8425628994 1.01512201  0.05
323    DNR ind6a  0.9288424546  0.8425628994 1.01512201  0.05
324    DNR ind6a  0.9288424546  0.8425628994 1.01512201  0.05
325    DNR ind6a  0.8794144817  0.7695262462 0.98930272  0.10
326    DNR ind6a  0.8794144817  0.7695262462 0.98930272  0.10
327    DNR ind6a  0.8794144817  0.7695262462 0.98930272  0.10
328    DNR ind6a  0.8794144817  0.7695262462 0.98930272  0.10
329    DNR ind6a  0.6485499834  0.5329934045 0.76410656  0.50
330    DNR ind6a  0.6485499834  0.5329934045 0.76410656  0.50
331    DNR ind6a  0.6485499834  0.5329934045 0.76410656  0.50
332    DNR ind6a  0.4993977679  0.3994046742 0.59939086  1.00
333    DNR ind6a  0.4993977679  0.3994046742 0.59939086  1.00
334    DNR ind6a  0.4993977679  0.3994046742 0.59939086  1.00
335    DNR ind6a  0.4993977679  0.3994046742 0.59939086  1.00
336    DNR ind6a  0.1638013099  0.0621608449 0.26544177  5.00
337    DNR ind6a  0.1638013099  0.0621608449 0.26544177  5.00
338    DNR ind6a  0.1638013099  0.0621608449 0.26544177  5.00
339    DNR ind6a  0.1638013099  0.0621608449 0.26544177  5.00
340    DNR ind6a  0.0664011117 -0.0274738890 0.16027611 10.00
341    DNR ind6a  0.0664011117 -0.0274738890 0.16027611 10.00
342    DNR ind6a  0.0664011117 -0.0274738890 0.16027611 10.00
343    DNR ind6a  0.0664011117 -0.0274738890 0.16027611 10.00
344    DNR ind6a -0.0491666133 -0.1770653574 0.07873213 50.00
345    DNR ind6a -0.0491666133 -0.1770653574 0.07873213 50.00
346    DNR ind6a -0.0491666133 -0.1770653574 0.07873213 50.00
347    DNR ind6a -0.0491666133 -0.1770653574 0.07873213 50.00
348    DNR ind6b  0.9386451459  0.8339387799 1.04335151  0.01
349    DNR ind6b  0.9386451459  0.8339387799 1.04335151  0.01
350    DNR ind6b  0.9386451459  0.8339387799 1.04335151  0.01
351    DNR ind6b  0.9386451459  0.8339387799 1.04335151  0.01
352    DNR ind6b  0.8426339007  0.6846643019 1.00060350  0.05
353    DNR ind6b  0.8426339007  0.6846643019 1.00060350  0.05
354    DNR ind6b  0.8426339007  0.6846643019 1.00060350  0.05
355    DNR ind6b  0.8426339007  0.6846643019 1.00060350  0.05
356    DNR ind6b  0.7718307038  0.6036098796 0.94005153  0.10
357    DNR ind6b  0.7718307038  0.6036098796 0.94005153  0.10
358    DNR ind6b  0.7718307038  0.6036098796 0.94005153  0.10
359    DNR ind6b  0.7718307038  0.6036098796 0.94005153  0.10
360    DNR ind6b  0.5277608506  0.3739932901 0.68152841  0.50
361    DNR ind6b  0.5277608506  0.3739932901 0.68152841  0.50
362    DNR ind6b  0.5277608506  0.3739932901 0.68152841  0.50
363    DNR ind6b  0.4006212773  0.2472836122 0.55395894  1.00
364    DNR ind6b  0.4006212773  0.2472836122 0.55395894  1.00
365    DNR ind6b  0.4006212773  0.2472836122 0.55395894  1.00
366    DNR ind6b  0.1322609008 -0.0162455228 0.28076732  5.00
367    DNR ind6b  0.1322609008 -0.0162455228 0.28076732  5.00
368    DNR ind6b  0.1322609008 -0.0162455228 0.28076732  5.00
369    DNR ind6b  0.1322609008 -0.0162455228 0.28076732  5.00
370    DNR ind6b  0.0477120199 -0.0961972274 0.19162127 10.00
371    DNR ind6b  0.0477120199 -0.0961972274 0.19162127 10.00
372    DNR ind6b  0.0477120199 -0.0961972274 0.19162127 10.00
373    DNR ind6b  0.0477120199 -0.0961972274 0.19162127 10.00
374    DNR ind6b -0.0723064481 -0.2767471939 0.13213430 50.00
375    DNR ind6b -0.0723064481 -0.2767471939 0.13213430 50.00
376    DNR ind6b -0.0723064481 -0.2767471939 0.13213430 50.00
377    DNR ind6b -0.0723064481 -0.2767471939 0.13213430 50.00
378    DOX ind1a  0.9561386598  0.8963463520 1.01593097  0.01
379    DOX ind1a  0.9561386598  0.8963463520 1.01593097  0.01
380    DOX ind1a  0.9561386598  0.8963463520 1.01593097  0.01
381    DOX ind1a  0.9561386598  0.8963463520 1.01593097  0.01
382    DOX ind1a  0.9099475681  0.8237441039 0.99615103  0.05
383    DOX ind1a  0.9099475681  0.8237441039 0.99615103  0.05
384    DOX ind1a  0.9099475681  0.8237441039 0.99615103  0.05
385    DOX ind1a  0.9099475681  0.8237441039 0.99615103  0.05
386    DOX ind1a  0.8783922851  0.7816701622 0.97511441  0.10
387    DOX ind1a  0.8783922851  0.7816701622 0.97511441  0.10
388    DOX ind1a  0.8783922851  0.7816701622 0.97511441  0.10
389    DOX ind1a  0.8783922851  0.7816701622 0.97511441  0.10
390    DOX ind1a  0.7644678941  0.6524030164 0.87653277  0.50
391    DOX ind1a  0.7644678941  0.6524030164 0.87653277  0.50
392    DOX ind1a  0.7644678941  0.6524030164 0.87653277  0.50
393    DOX ind1a  0.7644678941  0.6524030164 0.87653277  0.50
394    DOX ind1a  0.6937845029  0.5796623381 0.80790667  1.00
395    DOX ind1a  0.6937845029  0.5796623381 0.80790667  1.00
396    DOX ind1a  0.6937845029  0.5796623381 0.80790667  1.00
397    DOX ind1a  0.6937845029  0.5796623381 0.80790667  1.00
398    DOX ind1a  0.4772294330  0.3602464526 0.59421241  5.00
399    DOX ind1a  0.4772294330  0.3602464526 0.59421241  5.00
400    DOX ind1a  0.4772294330  0.3602464526 0.59421241  5.00
401    DOX ind1a  0.4772294330  0.3602464526 0.59421241  5.00
402    DOX ind1a  0.3669133079  0.2447880177 0.48903860 10.00
403    DOX ind1a  0.3669133079  0.2447880177 0.48903860 10.00
404    DOX ind1a  0.3669133079  0.2447880177 0.48903860 10.00
405    DOX ind1a  0.3669133079  0.2447880177 0.48903860 10.00
406    DOX ind1a  0.1067121182 -0.0978659541 0.31129019 50.00
407    DOX ind1a  0.1067121182 -0.0978659541 0.31129019 50.00
408    DOX ind1a  0.1067121182 -0.0978659541 0.31129019 50.00
409    DOX ind1a  0.1067121182 -0.0978659541 0.31129019 50.00
410    DOX ind1b  0.9859633704  0.9340328710 1.03789387  0.01
411    DOX ind1b  0.9859633704  0.9340328710 1.03789387  0.01
412    DOX ind1b  0.9859633704  0.9340328710 1.03789387  0.01
413    DOX ind1b  0.9354092985  0.8058073811 1.06501122  0.05
414    DOX ind1b  0.9354092985  0.8058073811 1.06501122  0.05
415    DOX ind1b  0.9354092985  0.8058073811 1.06501122  0.05
416    DOX ind1b  0.9354092985  0.8058073811 1.06501122  0.05
417    DOX ind1b  0.8808112518  0.7182560418 1.04336646  0.10
418    DOX ind1b  0.8808112518  0.7182560418 1.04336646  0.10
419    DOX ind1b  0.8808112518  0.7182560418 1.04336646  0.10
420    DOX ind1b  0.8808112518  0.7182560418 1.04336646  0.10
421    DOX ind1b  0.6215443520  0.3810235119 0.86206519  0.50
422    DOX ind1b  0.6215443520  0.3810235119 0.86206519  0.50
423    DOX ind1b  0.6215443520  0.3810235119 0.86206519  0.50
424    DOX ind1b  0.4767878020  0.1928631598 0.76071244  1.00
425    DOX ind1b  0.4767878020  0.1928631598 0.76071244  1.00
426    DOX ind1b  0.4767878020  0.1928631598 0.76071244  1.00
427    DOX ind1b  0.4767878020  0.1928631598 0.76071244  1.00
428    DOX ind1b  0.2417320273  0.0681245967 0.41533946  5.00
429    DOX ind1b  0.2417320273  0.0681245967 0.41533946  5.00
430    DOX ind1b  0.2417320273  0.0681245967 0.41533946  5.00
431    DOX ind1b  0.1957786752  0.0189310554 0.37262629 10.00
432    DOX ind1b  0.1957786752  0.0189310554 0.37262629 10.00
433    DOX ind1b  0.1957786752  0.0189310554 0.37262629 10.00
434    DOX ind1b  0.1957786752  0.0189310554 0.37262629 10.00
435    DOX ind1b  0.2417320273  0.0681245967 0.41533946  5.00
436    DOX ind1b  0.1542385955 -0.1216655564 0.43014275 50.00
437    DOX ind1b  0.1542385955 -0.1216655564 0.43014275 50.00
438    DOX ind1b  0.1542385955 -0.1216655564 0.43014275 50.00
439    DOX ind1b  0.1542385955 -0.1216655564 0.43014275 50.00
440    DOX ind2a  0.9916454195  0.9816339193 1.00165692  0.01
441    DOX ind2a  0.9916454195  0.9816339193 1.00165692  0.01
442    DOX ind2a  0.9916454195  0.9816339193 1.00165692  0.01
443    DOX ind2a  0.9916454195  0.9816339193 1.00165692  0.01
444    DOX ind2a  0.9750954570  0.9535081269 0.99668279  0.05
445    DOX ind2a  0.9750954570  0.9535081269 0.99668279  0.05
446    DOX ind2a  0.9750954570  0.9535081269 0.99668279  0.05
447    DOX ind2a  0.9750954570  0.9535081269 0.99668279  0.05
448    DOX ind2a  0.9603540596  0.9315551136 0.98915301  0.10
449    DOX ind2a  0.9603540596  0.9315551136 0.98915301  0.10
450    DOX ind2a  0.9603540596  0.9315551136 0.98915301  0.10
451    DOX ind2a  0.9603540596  0.9315551136 0.98915301  0.10
452    DOX ind2a  0.8867220547  0.8392122797 0.93423183  0.50
453    DOX ind2a  0.8867220547  0.8392122797 0.93423183  0.50
454    DOX ind2a  0.8867220547  0.8392122797 0.93423183  0.50
455    DOX ind2a  0.8867220547  0.8392122797 0.93423183  0.50
456    DOX ind2a  0.8867220547  0.8392122797 0.93423183  0.50
457    DOX ind2a  0.8260990584  0.7728551533 0.87934296  1.00
458    DOX ind2a  0.8260990584  0.7728551533 0.87934296  1.00
459    DOX ind2a  0.8260990584  0.7728551533 0.87934296  1.00
460    DOX ind2a  0.8260990584  0.7728551533 0.87934296  1.00
461    DOX ind2a  0.5782208792  0.5184824016 0.63795936  5.00
462    DOX ind2a  0.5782208792  0.5184824016 0.63795936  5.00
463    DOX ind2a  0.5782208792  0.5184824016 0.63795936  5.00
464    DOX ind2a  0.4241535179  0.3595505255 0.48875651 10.00
465    DOX ind2a  0.4241535179  0.3595505255 0.48875651 10.00
466    DOX ind2a  0.4241535179  0.3595505255 0.48875651 10.00
467    DOX ind2a  0.4241535179  0.3595505255 0.48875651 10.00
468    DOX ind2a  0.0384425481 -0.0511322433 0.12801734 50.00
469    DOX ind2a  0.0384425481 -0.0511322433 0.12801734 50.00
470    DOX ind2a  0.0384425481 -0.0511322433 0.12801734 50.00
471    DOX ind2a  0.0384425481 -0.0511322433 0.12801734 50.00
472    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.01
473    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.01
474    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.01
475    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.01
476    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.05
477    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.05
478    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.05
479    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.05
480    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.10
481    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.10
482    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.10
483    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.10
484    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
485    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
486    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
487    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
488    DOX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
489    DOX ind2b  1.0000000000  1.0000000000 1.00000000  1.00
490    DOX ind2b  1.0000000000  1.0000000000 1.00000000  1.00
491    DOX ind2b  1.0000000000  1.0000000000 1.00000000  1.00
492    DOX ind2b  1.0000000000  1.0000000000 1.00000000  1.00
493    DOX ind2b  0.9999999996           NaN        NaN  5.00
494    DOX ind2b  0.9999999996           NaN        NaN  5.00
495    DOX ind2b  0.9999999996           NaN        NaN  5.00
496    DOX ind2b  0.9999992128           NaN        NaN 10.00
497    DOX ind2b  0.9999992128           NaN        NaN 10.00
498    DOX ind2b  0.9999992128           NaN        NaN 10.00
499    DOX ind2b  0.9999992128           NaN        NaN 10.00
500    DOX ind2b  0.0262488752 -0.2317538610 0.28425161 50.00
501    DOX ind2b  0.0262488752 -0.2317538610 0.28425161 50.00
502    DOX ind2b  0.0262488752 -0.2317538610 0.28425161 50.00
503    DOX ind2b  0.0262488752 -0.2317538610 0.28425161 50.00
504    DOX ind3a  0.9494394719  0.8720934866 1.02678546  0.01
505    DOX ind3a  0.9494394719  0.8720934866 1.02678546  0.01
506    DOX ind3a  0.9494394719  0.8720934866 1.02678546  0.01
507    DOX ind3a  0.9494394719  0.8720934866 1.02678546  0.01
508    DOX ind3a  0.9017223256  0.8002846989 1.00315995  0.05
509    DOX ind3a  0.9017223256  0.8002846989 1.00315995  0.05
510    DOX ind3a  0.9017223256  0.8002846989 1.00315995  0.05
511    DOX ind3a  0.9017223256  0.8002846989 1.00315995  0.05
512    DOX ind3a  0.8701871435  0.7606417927 0.97973249  0.10
513    DOX ind3a  0.8701871435  0.7606417927 0.97973249  0.10
514    DOX ind3a  0.8701871435  0.7606417927 0.97973249  0.10
515    DOX ind3a  0.8701871435  0.7606417927 0.97973249  0.10
516    DOX ind3a  0.7595434412  0.6368126090 0.88227427  0.50
517    DOX ind3a  0.7595434412  0.6368126090 0.88227427  0.50
518    DOX ind3a  0.7595434412  0.6368126090 0.88227427  0.50
519    DOX ind3a  0.7595434412  0.6368126090 0.88227427  0.50
520    DOX ind3a  0.7595434412  0.6368126090 0.88227427  0.50
521    DOX ind3a  0.6919618776  0.5619086688 0.82201509  1.00
522    DOX ind3a  0.6919618776  0.5619086688 0.82201509  1.00
523    DOX ind3a  0.6919618776  0.5619086688 0.82201509  1.00
524    DOX ind3a  0.6919618776  0.5619086688 0.82201509  1.00
525    DOX ind3a  0.4839942404  0.3296805638 0.63830792  5.00
526    DOX ind3a  0.4839942404  0.3296805638 0.63830792  5.00
527    DOX ind3a  0.4839942404  0.3296805638 0.63830792  5.00
528    DOX ind3a  0.3754601353  0.2172281010 0.53369217 10.00
529    DOX ind3a  0.3754601353  0.2172281010 0.53369217 10.00
530    DOX ind3a  0.3754601353  0.2172281010 0.53369217 10.00
531    DOX ind3a  0.3754601353  0.2172281010 0.53369217 10.00
532    DOX ind3a  0.1057295798 -0.1449647699 0.35642393 50.00
533    DOX ind3a  0.1057295798 -0.1449647699 0.35642393 50.00
534    DOX ind3a  0.1057295798 -0.1449647699 0.35642393 50.00
535    DOX ind3a  0.1057295798 -0.1449647699 0.35642393 50.00
536    DOX ind3b  0.9306230731  0.8589139596 1.00233219  0.01
537    DOX ind3b  0.9306230731  0.8589139596 1.00233219  0.01
538    DOX ind3b  0.9306230731  0.8589139596 1.00233219  0.01
539    DOX ind3b  0.9306230731  0.8589139596 1.00233219  0.01
540    DOX ind3b  0.8725466452  0.7835474517 0.96154584  0.05
541    DOX ind3b  0.8725466452  0.7835474517 0.96154584  0.05
542    DOX ind3b  0.8725466452  0.7835474517 0.96154584  0.05
543    DOX ind3b  0.8725466452  0.7835474517 0.96154584  0.05
544    DOX ind3b  0.8358182500  0.7420095732 0.92962693  0.10
545    DOX ind3b  0.8358182500  0.7420095732 0.92962693  0.10
546    DOX ind3b  0.8358182500  0.7420095732 0.92962693  0.10
547    DOX ind3b  0.8358182500  0.7420095732 0.92962693  0.10
548    DOX ind3b  0.6421090549  0.5424084697 0.74180964  1.00
549    DOX ind3b  0.7134134721  0.6152570732 0.81156987  0.50
550    DOX ind3b  0.7134134721  0.6152570732 0.81156987  0.50
551    DOX ind3b  0.7134134721  0.6152570732 0.81156987  0.50
552    DOX ind3b  0.7134134721  0.6152570732 0.81156987  0.50
553    DOX ind3b  0.6421090549  0.5424084697 0.74180964  1.00
554    DOX ind3b  0.6421090549  0.5424084697 0.74180964  1.00
555    DOX ind3b  0.6421090549  0.5424084697 0.74180964  1.00
556    DOX ind3b  0.4330283726  0.3244776584 0.54157909  5.00
557    DOX ind3b  0.4330283726  0.3244776584 0.54157909  5.00
558    DOX ind3b  0.4330283726  0.3244776584 0.54157909  5.00
559    DOX ind3b  0.4330283726  0.3244776584 0.54157909  5.00
560    DOX ind3b  0.3281380335  0.2149654739 0.44131059 10.00
561    DOX ind3b  0.3281380335  0.2149654739 0.44131059 10.00
562    DOX ind3b  0.3281380335  0.2149654739 0.44131059 10.00
563    DOX ind3b  0.3281380335  0.2149654739 0.44131059 10.00
564    DOX ind3b  0.0743163872 -0.1126492209 0.26128200 50.00
565    DOX ind3b  0.0743163872 -0.1126492209 0.26128200 50.00
566    DOX ind3b  0.0743163872 -0.1126492209 0.26128200 50.00
567    DOX ind3b  0.0743163872 -0.1126492209 0.26128200 50.00
568    DOX ind4a  0.9761205655  0.9470850535 1.00515608  0.01
569    DOX ind4a  0.9761205655  0.9470850535 1.00515608  0.01
570    DOX ind4a  0.9761205655  0.9470850535 1.00515608  0.01
571    DOX ind4a  0.9761205655  0.9470850535 1.00515608  0.01
572    DOX ind4a  0.9289209805  0.8753769741 0.98246499  0.05
573    DOX ind4a  0.9289209805  0.8753769741 0.98246499  0.05
574    DOX ind4a  0.9289209805  0.8753769741 0.98246499  0.05
575    DOX ind4a  0.9289209805  0.8753769741 0.98246499  0.05
576    DOX ind4a  0.8887398548  0.8254863217 0.95199339  0.10
577    DOX ind4a  0.8887398548  0.8254863217 0.95199339  0.10
578    DOX ind4a  0.8887398548  0.8254863217 0.95199339  0.10
579    DOX ind4a  0.8887398548  0.8254863217 0.95199339  0.10
580    DOX ind4a  0.7166389721  0.6454384640 0.78783948  0.50
581    DOX ind4a  0.7166389721  0.6454384640 0.78783948  0.50
582    DOX ind4a  0.7166389721  0.6454384640 0.78783948  0.50
583    DOX ind4a  0.7166389721  0.6454384640 0.78783948  0.50
584    DOX ind4a  0.6050024807  0.5283229717 0.68168199  1.00
585    DOX ind4a  0.6050024807  0.5283229717 0.68168199  1.00
586    DOX ind4a  0.6050024807  0.5283229717 0.68168199  1.00
587    DOX ind4a  0.6050024807  0.5283229717 0.68168199  1.00
588    DOX ind4a  0.3150958325  0.2276080992 0.40258357  5.00
589    DOX ind4a  0.3150958325  0.2276080992 0.40258357  5.00
590    DOX ind4a  0.3150958325  0.2276080992 0.40258357  5.00
591    DOX ind4a  0.3150958325  0.2276080992 0.40258357  5.00
592    DOX ind4a  0.2090253043  0.1320602271 0.28599038 10.00
593    DOX ind4a  0.2090253043  0.1320602271 0.28599038 10.00
594    DOX ind4a  0.2090253043  0.1320602271 0.28599038 10.00
595    DOX ind4a  0.2090253043  0.1320602271 0.28599038 10.00
596    DOX ind4a  0.0511453813 -0.0725150783 0.17480584 50.00
597    DOX ind4a  0.0511453813 -0.0725150783 0.17480584 50.00
598    DOX ind4a  0.0511453813 -0.0725150783 0.17480584 50.00
599    DOX ind4a  0.0511453813 -0.0725150783 0.17480584 50.00
600    DOX ind4b  0.9122788753  0.7800135104 1.04454424  0.01
601    DOX ind4b  0.9122788753  0.7800135104 1.04454424  0.01
602    DOX ind4b  0.9122788753  0.7800135104 1.04454424  0.01
603    DOX ind4b  0.9122788753  0.7800135104 1.04454424  0.01
604    DOX ind4b  0.7832222478  0.6291018096 0.93734269  0.05
605    DOX ind4b  0.7832222478  0.6291018096 0.93734269  0.05
606    DOX ind4b  0.7832222478  0.6291018096 0.93734269  0.05
607    DOX ind4b  0.7832222478  0.6291018096 0.93734269  0.05
608    DOX ind4b  0.6961704451  0.5608994072 0.83144148  0.10
609    DOX ind4b  0.6961704451  0.5608994072 0.83144148  0.10
610    DOX ind4b  0.6961704451  0.5608994072 0.83144148  0.10
611    DOX ind4b  0.4430482810  0.3291028694 0.55699369  0.50
612    DOX ind4b  0.4430482810  0.3291028694 0.55699369  0.50
613    DOX ind4b  0.4430482810  0.3291028694 0.55699369  0.50
614    DOX ind4b  0.4430482810  0.3291028694 0.55699369  0.50
615    DOX ind4b  0.3351853049  0.2057374332 0.46463318  1.00
616    DOX ind4b  0.3351853049  0.2057374332 0.46463318  1.00
617    DOX ind4b  0.3351853049  0.2057374332 0.46463318  1.00
618    DOX ind4b  0.3351853049  0.2057374332 0.46463318  1.00
619    DOX ind4b  0.1485666400  0.0433778763 0.25375540  5.00
620    DOX ind4b  0.1485666400  0.0433778763 0.25375540  5.00
621    DOX ind4b  0.1485666400  0.0433778763 0.25375540  5.00
622    DOX ind4b  0.1485666400  0.0433778763 0.25375540  5.00
623    DOX ind4b  0.0993295937 -0.0007851429 0.19944433 10.00
624    DOX ind4b  0.0993295937 -0.0007851429 0.19944433 10.00
625    DOX ind4b  0.0993295937 -0.0007851429 0.19944433 10.00
626    DOX ind4b  0.0993295937 -0.0007851429 0.19944433 10.00
627    DOX ind4b  0.0362552220 -0.1203498553 0.19286030 50.00
628    DOX ind4b  0.0362552220 -0.1203498553 0.19286030 50.00
629    DOX ind4b  0.0362552220 -0.1203498553 0.19286030 50.00
630    DOX ind4b  0.0362552220 -0.1203498553 0.19286030 50.00
631    DOX ind5a  0.9442025849  0.8936330654 0.99477210  0.01
632    DOX ind5a  0.9442025849  0.8936330654 0.99477210  0.01
633    DOX ind5a  0.9442025849  0.8936330654 0.99477210  0.01
634    DOX ind5a  0.9442025849  0.8936330654 0.99477210  0.01
635    DOX ind5a  0.8930823049  0.8310023320 0.95516228  0.05
636    DOX ind5a  0.8930823049  0.8310023320 0.95516228  0.05
637    DOX ind5a  0.8930823049  0.8310023320 0.95516228  0.05
638    DOX ind5a  0.8930823049  0.8310023320 0.95516228  0.05
639    DOX ind5a  0.8596166784  0.7950105219 0.92422283  0.10
640    DOX ind5a  0.8596166784  0.7950105219 0.92422283  0.10
641    DOX ind5a  0.8596166784  0.7950105219 0.92422283  0.10
642    DOX ind5a  0.8596166784  0.7950105219 0.92422283  0.10
643    DOX ind5a  0.7432992990  0.6752620697 0.81133653  0.50
644    DOX ind5a  0.7432992990  0.6752620697 0.81133653  0.50
645    DOX ind5a  0.7432992990  0.6752620697 0.81133653  0.50
646    DOX ind5a  0.7432992990  0.6752620697 0.81133653  0.50
647    DOX ind5a  0.7432992990  0.6752620697 0.81133653  0.50
648    DOX ind5a  0.6727457857  0.5986577297 0.74683384  1.00
649    DOX ind5a  0.6727457857  0.5986577297 0.74683384  1.00
650    DOX ind5a  0.6727457857  0.5986577297 0.74683384  1.00
651    DOX ind5a  0.6727457857  0.5986577297 0.74683384  1.00
652    DOX ind5a  0.4564903502  0.3588981442 0.55408256  5.00
653    DOX ind5a  0.4564903502  0.3588981442 0.55408256  5.00
654    DOX ind5a  0.4564903502  0.3588981442 0.55408256  5.00
655    DOX ind5a  0.3436320666  0.2454766990 0.44178743 10.00
656    DOX ind5a  0.3436320666  0.2454766990 0.44178743 10.00
657    DOX ind5a  0.3436320666  0.2454766990 0.44178743 10.00
658    DOX ind5a  0.3436320666  0.2454766990 0.44178743 10.00
659    DOX ind5a  0.0615221140 -0.0857499204 0.20879415 50.00
660    DOX ind5a  0.0615221140 -0.0857499204 0.20879415 50.00
661    DOX ind5a  0.0615221140 -0.0857499204 0.20879415 50.00
662    DOX ind5a  0.0615221140 -0.0857499204 0.20879415 50.00
663    DOX ind5b  0.9922729465  0.9681018168 1.01644408  0.01
664    DOX ind5b  0.9922729465  0.9681018168 1.01644408  0.01
665    DOX ind5b  0.9922729465  0.9681018168 1.01644408  0.01
666    DOX ind5b  0.9922729465  0.9681018168 1.01644408  0.01
667    DOX ind5b  0.9756968572  0.9206121746 1.03078154  0.05
668    DOX ind5b  0.9756968572  0.9206121746 1.03078154  0.05
669    DOX ind5b  0.9756968572  0.9206121746 1.03078154  0.05
670    DOX ind5b  0.9756968572  0.9206121746 1.03078154  0.05
671    DOX ind5b  0.9604503905  0.8850601189 1.03584066  0.10
672    DOX ind5b  0.9604503905  0.8850601189 1.03584066  0.10
673    DOX ind5b  0.9604503905  0.8850601189 1.03584066  0.10
674    DOX ind5b  0.9604503905  0.8850601189 1.03584066  0.10
675    DOX ind5b  0.8819293117  0.7473863884 1.01647224  0.50
676    DOX ind5b  0.8819293117  0.7473863884 1.01647224  0.50
677    DOX ind5b  0.8819293117  0.7473863884 1.01647224  0.50
678    DOX ind5b  0.8819293117  0.7473863884 1.01647224  0.50
679    DOX ind5b  0.8164375300  0.6567133138 0.97616175  1.00
680    DOX ind5b  0.8164375300  0.6567133138 0.97616175  1.00
681    DOX ind5b  0.8164375300  0.6567133138 0.97616175  1.00
682    DOX ind5b  0.8164375300  0.6567133138 0.97616175  1.00
683    DOX ind5b  0.5544530293  0.3475106150 0.76139544  5.00
684    DOX ind5b  0.5544530293  0.3475106150 0.76139544  5.00
685    DOX ind5b  0.5544530293  0.3475106150 0.76139544  5.00
686    DOX ind5b  0.5544530293  0.3475106150 0.76139544  5.00
687    DOX ind5b  0.4007613398  0.1892099480 0.61231273 10.00
688    DOX ind5b  0.4007613398  0.1892099480 0.61231273 10.00
689    DOX ind5b  0.4007613398  0.1892099480 0.61231273 10.00
690    DOX ind5b  0.4007613398  0.1892099480 0.61231273 10.00
691    DOX ind5b  0.0553141137 -0.2575216930 0.36814992 50.00
692    DOX ind5b  0.0553141137 -0.2575216930 0.36814992 50.00
693    DOX ind5b  0.0553141137 -0.2575216930 0.36814992 50.00
694    DOX ind5b  0.0553141137 -0.2575216930 0.36814992 50.00
695    DOX ind6a  0.9744783113  0.9155956176 1.03336100  0.01
696    DOX ind6a  0.9744783113  0.9155956176 1.03336100  0.01
697    DOX ind6a  0.9744783113  0.9155956176 1.03336100  0.01
698    DOX ind6a  0.9318183434  0.8316481100 1.03198858  0.05
699    DOX ind6a  0.9318183434  0.8316481100 1.03198858  0.05
700    DOX ind6a  0.9318183434  0.8316481100 1.03198858  0.05
701    DOX ind6a  0.9318183434  0.8316481100 1.03198858  0.05
702    DOX ind6a  0.8974964277  0.7820694615 1.01292339  0.10
703    DOX ind6a  0.8974964277  0.7820694615 1.01292339  0.10
704    DOX ind6a  0.8974964277  0.7820694615 1.01292339  0.10
705    DOX ind6a  0.8974964277  0.7820694615 1.01292339  0.10
706    DOX ind6a  0.7541265614  0.6388750150 0.86937811  0.50
707    DOX ind6a  0.7541265614  0.6388750150 0.86937811  0.50
708    DOX ind6a  0.7541265614  0.6388750150 0.86937811  0.50
709    DOX ind6a  0.7541265614  0.6388750150 0.86937811  0.50
710    DOX ind6a  0.6584227543  0.5520869671 0.76475854  1.00
711    DOX ind6a  0.6584227543  0.5520869671 0.76475854  1.00
712    DOX ind6a  0.6584227543  0.5520869671 0.76475854  1.00
713    DOX ind6a  0.6584227543  0.5520869671 0.76475854  1.00
714    DOX ind6a  0.3779564585  0.2371666492 0.51874627  5.00
715    DOX ind6a  0.3779564585  0.2371666492 0.51874627  5.00
716    DOX ind6a  0.3779564585  0.2371666492 0.51874627  5.00
717    DOX ind6a  0.3779564585  0.2371666492 0.51874627  5.00
718    DOX ind6a  0.2555012970  0.1194651559 0.39153744 10.00
719    DOX ind6a  0.2555012970  0.1194651559 0.39153744 10.00
720    DOX ind6a  0.2555012970  0.1194651559 0.39153744 10.00
721    DOX ind6a  0.2555012970  0.1194651559 0.39153744 10.00
722    DOX ind6a  0.0355816246 -0.1549810611 0.22614431 50.00
723    DOX ind6a  0.0355816246 -0.1549810611 0.22614431 50.00
724    DOX ind6a  0.0355816246 -0.1549810611 0.22614431 50.00
725    DOX ind6a  0.0355816246 -0.1549810611 0.22614431 50.00
726    DOX ind6b  0.9983270140  0.9826347251 1.01401930  0.01
727    DOX ind6b  0.9983270140  0.9826347251 1.01401930  0.01
728    DOX ind6b  0.9983270140  0.9826347251 1.01401930  0.01
729    DOX ind6b  0.9983270140  0.9826347251 1.01401930  0.01
730    DOX ind6b  0.9847915152  0.8988842642 1.07069877  0.05
731    DOX ind6b  0.9847915152  0.8988842642 1.07069877  0.05
732    DOX ind6b  0.9847915152  0.8988842642 1.07069877  0.05
733    DOX ind6b  0.9847915152  0.8988842642 1.07069877  0.05
734    DOX ind6b  0.9614430556  0.8064505044 1.11643561  0.10
735    DOX ind6b  0.9614430556  0.8064505044 1.11643561  0.10
736    DOX ind6b  0.9614430556  0.8064505044 1.11643561  0.10
737    DOX ind6b  0.9614430556  0.8064505044 1.11643561  0.10
738    DOX ind6b  0.7372720756  0.5230743199 0.95146983  0.50
739    DOX ind6b  0.7372720756  0.5230743199 0.95146983  0.50
740    DOX ind6b  0.7372720756  0.5230743199 0.95146983  0.50
741    DOX ind6b  0.7372720756  0.5230743199 0.95146983  0.50
742    DOX ind6b  0.5348618822  0.2236377636 0.84608600  1.00
743    DOX ind6b  0.5348618822  0.2236377636 0.84608600  1.00
744    DOX ind6b  0.5348618822  0.2236377636 0.84608600  1.00
745    DOX ind6b  0.5348618822  0.2236377636 0.84608600  1.00
746    DOX ind6b  0.1865646027 -0.0404461690 0.41357537  5.00
747    DOX ind6b  0.1865646027 -0.0404461690 0.41357537  5.00
748    DOX ind6b  0.1865646027 -0.0404461690 0.41357537  5.00
749    DOX ind6b  0.1865646027 -0.0404461690 0.41357537  5.00
750    DOX ind6b  0.1382682996 -0.0421428264 0.31867943 10.00
751    DOX ind6b  0.1382682996 -0.0421428264 0.31867943 10.00
752    DOX ind6b  0.1382682996 -0.0421428264 0.31867943 10.00
753    DOX ind6b  0.1382682996 -0.0421428264 0.31867943 10.00
754    DOX ind6b  0.1088622607 -0.1783413810 0.39606590 50.00
755    DOX ind6b  0.1088622607 -0.1783413810 0.39606590 50.00
756    DOX ind6b  0.1088622607 -0.1783413810 0.39606590 50.00
757    DOX ind6b  0.1088622607 -0.1783413810 0.39606590 50.00
758    EPI ind1a  0.9601326692  0.9025690119 1.01769633  0.01
759    EPI ind1a  0.9601326692  0.9025690119 1.01769633  0.01
760    EPI ind1a  0.9601326692  0.9025690119 1.01769633  0.01
761    EPI ind1a  0.9601326692  0.9025690119 1.01769633  0.01
762    EPI ind1a  0.9172017849  0.8318815956 1.00252197  0.05
763    EPI ind1a  0.9172017849  0.8318815956 1.00252197  0.05
764    EPI ind1a  0.9172017849  0.8318815956 1.00252197  0.05
765    EPI ind1a  0.9172017849  0.8318815956 1.00252197  0.05
766    EPI ind1a  0.8876337094  0.7904204508 0.98484697  0.10
767    EPI ind1a  0.8876337094  0.7904204508 0.98484697  0.10
768    EPI ind1a  0.8876337094  0.7904204508 0.98484697  0.10
769    EPI ind1a  0.8876337094  0.7904204508 0.98484697  0.10
770    EPI ind1a  0.7799296346  0.6622280864 0.89763118  0.50
771    EPI ind1a  0.7799296346  0.6622280864 0.89763118  0.50
772    EPI ind1a  0.7799296346  0.6622280864 0.89763118  0.50
773    EPI ind1a  0.7799296346  0.6622280864 0.89763118  0.50
774    EPI ind1a  0.7126180292  0.5906866294 0.83454943  1.00
775    EPI ind1a  0.7126180292  0.5906866294 0.83454943  1.00
776    EPI ind1a  0.7126180292  0.5906866294 0.83454943  1.00
777    EPI ind1a  0.7126180292  0.5906866294 0.83454943  1.00
778    EPI ind1a  0.5052163974  0.3816949573 0.62873784  5.00
779    EPI ind1a  0.5052163974  0.3816949573 0.62873784  5.00
780    EPI ind1a  0.5052163974  0.3816949573 0.62873784  5.00
781    EPI ind1a  0.5052163974  0.3816949573 0.62873784  5.00
782    EPI ind1a  0.3992758887  0.2737002798 0.52485150 10.00
783    EPI ind1a  0.3992758887  0.2737002798 0.52485150 10.00
784    EPI ind1a  0.3992758887  0.2737002798 0.52485150 10.00
785    EPI ind1a  0.3992758887  0.2737002798 0.52485150 10.00
786    EPI ind1a  0.1497936877 -0.0612897224 0.36087710 50.00
787    EPI ind1a  0.1497936877 -0.0612897224 0.36087710 50.00
788    EPI ind1a  0.1497936877 -0.0612897224 0.36087710 50.00
789    EPI ind1a  0.1497936877 -0.0612897224 0.36087710 50.00
790    EPI ind1b  0.9122523730  0.8004612945 1.02404345  0.01
791    EPI ind1b  0.9122523730  0.8004612945 1.02404345  0.01
792    EPI ind1b  0.9122523730  0.8004612945 1.02404345  0.01
793    EPI ind1b  0.8369493665  0.7182666852 0.95563205  0.05
794    EPI ind1b  0.8369493665  0.7182666852 0.95563205  0.05
795    EPI ind1b  0.8369493665  0.7182666852 0.95563205  0.05
796    EPI ind1b  0.8369493665  0.7182666852 0.95563205  0.05
797    EPI ind1b  0.7907216634  0.6702967948 0.91114653  0.10
798    EPI ind1b  0.7907216634  0.6702967948 0.91114653  0.10
799    EPI ind1b  0.7907216634  0.6702967948 0.91114653  0.10
800    EPI ind1b  0.6473511127  0.4913242396 0.80337799  0.50
801    EPI ind1b  0.6473511127  0.4913242396 0.80337799  0.50
802    EPI ind1b  0.6473511127  0.4913242396 0.80337799  0.50
803    EPI ind1b  0.6473511127  0.4913242396 0.80337799  0.50
804    EPI ind1b  0.5718543522  0.3924337313 0.75127497  1.00
805    EPI ind1b  0.5718543522  0.3924337313 0.75127497  1.00
806    EPI ind1b  0.5718543522  0.3924337313 0.75127497  1.00
807    EPI ind1b  0.5718543522  0.3924337313 0.75127497  1.00
808    EPI ind1b  0.3821946436  0.2067606569 0.55762863  5.00
809    EPI ind1b  0.3821946436  0.2067606569 0.55762863  5.00
810    EPI ind1b  0.3821946436  0.2067606569 0.55762863  5.00
811    EPI ind1b  0.3026862707  0.1534583918 0.45191415 10.00
812    EPI ind1b  0.3026862707  0.1534583918 0.45191415 10.00
813    EPI ind1b  0.3026862707  0.1534583918 0.45191415 10.00
814    EPI ind1b  0.3026862707  0.1534583918 0.45191415 10.00
815    EPI ind1b  0.1448792805 -0.1440938480 0.43385241 50.00
816    EPI ind1b  0.1448792805 -0.1440938480 0.43385241 50.00
817    EPI ind1b  0.1448792805 -0.1440938480 0.43385241 50.00
818    EPI ind1b  0.1448792805 -0.1440938480 0.43385241 50.00
819    EPI ind2a  0.9794633236  0.9571353200 1.00179133  0.01
820    EPI ind2a  0.9794633236  0.9571353200 1.00179133  0.01
821    EPI ind2a  0.9794633236  0.9571353200 1.00179133  0.01
822    EPI ind2a  0.9794633236  0.9571353200 1.00179133  0.01
823    EPI ind2a  0.9482936986  0.9083299194 0.98825748  0.05
824    EPI ind2a  0.9482936986  0.9083299194 0.98825748  0.05
825    EPI ind2a  0.9482936986  0.9083299194 0.98825748  0.05
826    EPI ind2a  0.9482936986  0.9083299194 0.98825748  0.05
827    EPI ind2a  0.9237376701  0.8747864502 0.97268889  0.10
828    EPI ind2a  0.9237376701  0.8747864502 0.97268889  0.10
829    EPI ind2a  0.9237376701  0.8747864502 0.97268889  0.10
830    EPI ind2a  0.9237376701  0.8747864502 0.97268889  0.10
831    EPI ind2a  0.8196988787  0.7537170151 0.88568074  0.50
832    EPI ind2a  0.8196988787  0.7537170151 0.88568074  0.50
833    EPI ind2a  0.8196988787  0.7537170151 0.88568074  0.50
834    EPI ind2a  0.8196988787  0.7537170151 0.88568074  0.50
835    EPI ind2a  0.7462612452  0.6776750149 0.81484748  1.00
836    EPI ind2a  0.7462612452  0.6776750149 0.81484748  1.00
837    EPI ind2a  0.7462612452  0.6776750149 0.81484748  1.00
838    EPI ind2a  0.7462612452  0.6776750149 0.81484748  1.00
839    EPI ind2a  0.4976634855  0.4294649226 0.56586205  5.00
840    EPI ind2a  0.4976634855  0.4294649226 0.56586205  5.00
841    EPI ind2a  0.4976634855  0.4294649226 0.56586205  5.00
842    EPI ind2a  0.4976634855  0.4294649226 0.56586205  5.00
843    EPI ind2a  0.3658541387  0.2954349214 0.43627336 10.00
844    EPI ind2a  0.3658541387  0.2954349214 0.43627336 10.00
845    EPI ind2a  0.3658541387  0.2954349214 0.43627336 10.00
846    EPI ind2a  0.3658541387  0.2954349214 0.43627336 10.00
847    EPI ind2a  0.0690599513 -0.0415093904 0.17962929 50.00
848    EPI ind2a  0.0690599513 -0.0415093904 0.17962929 50.00
849    EPI ind2a  0.0690599513 -0.0415093904 0.17962929 50.00
850    EPI ind2a  0.0690599513 -0.0415093904 0.17962929 50.00
851    EPI ind2b  0.9857503214  0.9463860535 1.02511459  0.01
852    EPI ind2b  0.9857503214  0.9463860535 1.02511459  0.01
853    EPI ind2b  0.9857503214  0.9463860535 1.02511459  0.01
854    EPI ind2b  0.9857503214  0.9463860535 1.02511459  0.01
855    EPI ind2b  0.9601956241  0.8821813215 1.03820993  0.05
856    EPI ind2b  0.9601956241  0.8821813215 1.03820993  0.05
857    EPI ind2b  0.9601956241  0.8821813215 1.03820993  0.05
858    EPI ind2b  0.9601956241  0.8821813215 1.03820993  0.05
859    EPI ind2b  0.9386177667  0.8389670970 1.03826844  0.10
860    EPI ind2b  0.9386177667  0.8389670970 1.03826844  0.10
861    EPI ind2b  0.9386177667  0.8389670970 1.03826844  0.10
862    EPI ind2b  0.9386177667  0.8389670970 1.03826844  0.10
863    EPI ind2b  0.8398124414  0.6939000138 0.98572487  0.50
864    EPI ind2b  0.8398124414  0.6939000138 0.98572487  0.50
865    EPI ind2b  0.8398124414  0.6939000138 0.98572487  0.50
866    EPI ind2b  0.8398124414  0.6939000138 0.98572487  0.50
867    EPI ind2b  0.7659692268  0.6102548125 0.92168364  1.00
868    EPI ind2b  0.7659692268  0.6102548125 0.92168364  1.00
869    EPI ind2b  0.7659692268  0.6102548125 0.92168364  1.00
870    EPI ind2b  0.7659692268  0.6102548125 0.92168364  1.00
871    EPI ind2b  0.5078087294  0.3446475437 0.67096992  5.00
872    EPI ind2b  0.5078087294  0.3446475437 0.67096992  5.00
873    EPI ind2b  0.5078087294  0.3446475437 0.67096992  5.00
874    EPI ind2b  0.5078087294  0.3446475437 0.67096992  5.00
875    EPI ind2b  0.3720204508  0.2048368720 0.53920403 10.00
876    EPI ind2b  0.3720204508  0.2048368720 0.53920403 10.00
877    EPI ind2b  0.3720204508  0.2048368720 0.53920403 10.00
878    EPI ind2b  0.3720204508  0.2048368720 0.53920403 10.00
879    EPI ind2b  0.0847006077 -0.1702785173 0.33967973 50.00
880    EPI ind2b  0.0847006077 -0.1702785173 0.33967973 50.00
881    EPI ind2b  0.0847006077 -0.1702785173 0.33967973 50.00
882    EPI ind2b  0.0847006077 -0.1702785173 0.33967973 50.00
883    EPI ind3a  1.0000000000  1.0000000000 1.00000000  0.01
884    EPI ind3a  1.0000000000  1.0000000000 1.00000000  0.01
885    EPI ind3a  1.0000000000  1.0000000000 1.00000000  0.01
886    EPI ind3a  1.0000000000  1.0000000000 1.00000000  0.01
887    EPI ind3a  1.0000000000  1.0000000000 1.00000000  0.05
888    EPI ind3a  1.0000000000  1.0000000000 1.00000000  0.05
889    EPI ind3a  1.0000000000  1.0000000000 1.00000000  0.05
890    EPI ind3a  1.0000000000  1.0000000000 1.00000000  0.05
891    EPI ind3a  1.0000000000  0.9999999989 1.00000000  0.10
892    EPI ind3a  1.0000000000  0.9999999989 1.00000000  0.10
893    EPI ind3a  1.0000000000  0.9999999989 1.00000000  0.10
894    EPI ind3a  1.0000000000  0.9999999989 1.00000000  0.10
895    EPI ind3a  0.8584816420  0.5163752842 1.20058800  0.50
896    EPI ind3a  0.8584816420  0.5163752842 1.20058800  0.50
897    EPI ind3a  0.8584816420  0.5163752842 1.20058800  0.50
898    EPI ind3a  0.8584816420  0.5163752842 1.20058800  0.50
899    EPI ind3a  0.3071840182  0.1357682060 0.47859983  1.00
900    EPI ind3a  0.3071840182  0.1357682060 0.47859983  1.00
901    EPI ind3a  0.3071840182  0.1357682060 0.47859983  1.00
902    EPI ind3a  0.3071840182  0.1357682060 0.47859983  1.00
903    EPI ind3a  0.3071376947  0.1360395000 0.47823589  5.00
904    EPI ind3a  0.3071376947  0.1360395000 0.47823589  5.00
905    EPI ind3a  0.3071376947  0.1360395000 0.47823589  5.00
906    EPI ind3a  0.3071376947  0.1360395000 0.47823589  5.00
907    EPI ind3a  0.3071376947  0.1360395000 0.47823589 10.00
908    EPI ind3a  0.3071376947  0.1360395000 0.47823589 10.00
909    EPI ind3a  0.3071376947  0.1360395000 0.47823589 10.00
910    EPI ind3a  0.3071376947  0.1360395000 0.47823589 10.00
911    EPI ind3a  0.3071376947  0.1360395000 0.47823589 50.00
912    EPI ind3a  0.3071376947  0.1360395000 0.47823589 50.00
913    EPI ind3a  0.3071376947  0.1360395000 0.47823589 50.00
914    EPI ind3a  0.3071376947  0.1360395000 0.47823589 50.00
915    EPI ind3b  0.9804544021  0.9431329805 1.01777582  0.01
916    EPI ind3b  0.9804544021  0.9431329805 1.01777582  0.01
917    EPI ind3b  0.9413352721  0.8706039316 1.01206661  0.05
918    EPI ind3b  0.9413352721  0.8706039316 1.01206661  0.05
919    EPI ind3b  0.9413352721  0.8706039316 1.01206661  0.05
920    EPI ind3b  0.9413352721  0.8706039316 1.01206661  0.05
921    EPI ind3b  0.9074897507  0.8216327904 0.99334671  0.10
922    EPI ind3b  0.9074897507  0.8216327904 0.99334671  0.10
923    EPI ind3b  0.9074897507  0.8216327904 0.99334671  0.10
924    EPI ind3b  0.9074897507  0.8216327904 0.99334671  0.10
925    EPI ind3b  0.7564980636  0.6446607555 0.86833537  0.50
926    EPI ind3b  0.7564980636  0.6446607555 0.86833537  0.50
927    EPI ind3b  0.7564980636  0.6446607555 0.86833537  0.50
928    EPI ind3b  0.7564980636  0.6446607555 0.86833537  0.50
929    EPI ind3b  0.6529553062  0.5239675860 0.78194303  1.00
930    EPI ind3b  0.6529553062  0.5239675860 0.78194303  1.00
931    EPI ind3b  0.6529553062  0.5239675860 0.78194303  1.00
932    EPI ind3b  0.6529553062  0.5239675860 0.78194303  1.00
933    EPI ind3b  0.3608411744  0.2069897216 0.51469263  5.00
934    EPI ind3b  0.3608411744  0.2069897216 0.51469263  5.00
935    EPI ind3b  0.3608411744  0.2069897216 0.51469263  5.00
936    EPI ind3b  0.3608411744  0.2069897216 0.51469263  5.00
937    EPI ind3b  0.2446141450  0.1130016383 0.37622665 10.00
938    EPI ind3b  0.2446141450  0.1130016383 0.37622665 10.00
939    EPI ind3b  0.2446141450  0.1130016383 0.37622665 10.00
940    EPI ind3b  0.2446141450  0.1130016383 0.37622665 10.00
941    EPI ind3b  0.0611133327 -0.1596568771 0.28188354 50.00
942    EPI ind3b  0.0611133327 -0.1596568771 0.28188354 50.00
943    EPI ind3b  0.0611133327 -0.1596568771 0.28188354 50.00
944    EPI ind3b  0.0611133327 -0.1596568771 0.28188354 50.00
945    EPI ind4a  0.9844563658  0.9616468191 1.00726591  0.01
946    EPI ind4a  0.9844563658  0.9616468191 1.00726591  0.01
947    EPI ind4a  0.9844563658  0.9616468191 1.00726591  0.01
948    EPI ind4a  0.9844563658  0.9616468191 1.00726591  0.01
949    EPI ind4a  0.9485746312  0.9000951755 0.99705409  0.05
950    EPI ind4a  0.9485746312  0.9000951755 0.99705409  0.05
951    EPI ind4a  0.9485746312  0.9000951755 0.99705409  0.05
952    EPI ind4a  0.9485746312  0.9000951755 0.99705409  0.05
953    EPI ind4a  0.9154555004  0.8538609913 0.97705001  0.10
954    EPI ind4a  0.9154555004  0.8538609913 0.97705001  0.10
955    EPI ind4a  0.9154555004  0.8538609913 0.97705001  0.10
956    EPI ind4a  0.9154555004  0.8538609913 0.97705001  0.10
957    EPI ind4a  0.7570039795  0.6755480887 0.83845987  0.50
958    EPI ind4a  0.7570039795  0.6755480887 0.83845987  0.50
959    EPI ind4a  0.7570039795  0.6755480887 0.83845987  0.50
960    EPI ind4a  0.7570039795  0.6755480887 0.83845987  0.50
961    EPI ind4a  0.6436791787  0.5546098772 0.73274848  1.00
962    EPI ind4a  0.6436791787  0.5546098772 0.73274848  1.00
963    EPI ind4a  0.6436791787  0.5546098772 0.73274848  1.00
964    EPI ind4a  0.6436791787  0.5546098772 0.73274848  1.00
965    EPI ind4a  0.3249004189  0.2205971575 0.42920368  5.00
966    EPI ind4a  0.3249004189  0.2205971575 0.42920368  5.00
967    EPI ind4a  0.3249004189  0.2205971575 0.42920368  5.00
968    EPI ind4a  0.3249004189  0.2205971575 0.42920368  5.00
969    EPI ind4a  0.2040636105  0.1129524493 0.29517477 10.00
970    EPI ind4a  0.2040636105  0.1129524493 0.29517477 10.00
971    EPI ind4a  0.2040636105  0.1129524493 0.29517477 10.00
972    EPI ind4a  0.2040636105  0.1129524493 0.29517477 10.00
973    EPI ind4a  0.0278891586 -0.1176230228 0.17340134 50.00
974    EPI ind4a  0.0278891586 -0.1176230228 0.17340134 50.00
975    EPI ind4a  0.0278891586 -0.1176230228 0.17340134 50.00
976    EPI ind4a  0.0278891586 -0.1176230228 0.17340134 50.00
977    EPI ind4b  0.9408880004  0.9015077346 0.98026827  0.01
978    EPI ind4b  0.9408880004  0.9015077346 0.98026827  0.01
979    EPI ind4b  0.9408880004  0.9015077346 0.98026827  0.01
980    EPI ind4b  0.9408880004  0.9015077346 0.98026827  0.01
981    EPI ind4b  0.7985710897  0.7421006859 0.85504149  0.05
982    EPI ind4b  0.7985710897  0.7421006859 0.85504149  0.05
983    EPI ind4b  0.7985710897  0.7421006859 0.85504149  0.05
984    EPI ind4b  0.7985710897  0.7421006859 0.85504149  0.05
985    EPI ind4b  0.6873369903  0.6353375568 0.73933642  0.10
986    EPI ind4b  0.6873369903  0.6353375568 0.73933642  0.10
987    EPI ind4b  0.6873369903  0.6353375568 0.73933642  0.10
988    EPI ind4b  0.6873369903  0.6353375568 0.73933642  0.10
989    EPI ind4b  0.3726331049  0.3111846283 0.43408158  0.50
990    EPI ind4b  0.3726331049  0.3111846283 0.43408158  0.50
991    EPI ind4b  0.3726331049  0.3111846283 0.43408158  0.50
992    EPI ind4b  0.3726331049  0.3111846283 0.43408158  0.50
993    EPI ind4b  0.2630201767  0.2048392007 0.32120115  1.00
994    EPI ind4b  0.2630201767  0.2048392007 0.32120115  1.00
995    EPI ind4b  0.2630201767  0.2048392007 0.32120115  1.00
996    EPI ind4b  0.2630201767  0.2048392007 0.32120115  1.00
997    EPI ind4b  0.1239882731  0.0841117477 0.16386480  5.00
998    EPI ind4b  0.1239882731  0.0841117477 0.16386480  5.00
999    EPI ind4b  0.1239882731  0.0841117477 0.16386480  5.00
1000   EPI ind4b  0.1239882731  0.0841117477 0.16386480  5.00
1001   EPI ind4b  0.0988677913  0.0534600640 0.14427552 10.00
1002   EPI ind4b  0.0988677913  0.0534600640 0.14427552 10.00
1003   EPI ind4b  0.0988677913  0.0534600640 0.14427552 10.00
1004   EPI ind4b  0.0988677913  0.0534600640 0.14427552 10.00
1005   EPI ind4b  0.0747668733  0.0139143296 0.13561942 50.00
1006   EPI ind4b  0.0747668733  0.0139143296 0.13561942 50.00
1007   EPI ind4b  0.0747668733  0.0139143296 0.13561942 50.00
1008   EPI ind4b  0.0747668733  0.0139143296 0.13561942 50.00
1009   EPI ind5a  0.9492823169  0.8844648154 1.01409982  0.01
1010   EPI ind5a  0.9492823169  0.8844648154 1.01409982  0.01
1011   EPI ind5a  0.9492823169  0.8844648154 1.01409982  0.01
1012   EPI ind5a  0.9492823169  0.8844648154 1.01409982  0.01
1013   EPI ind5a  0.8952688897  0.8108363769 0.97970140  0.05
1014   EPI ind5a  0.8952688897  0.8108363769 0.97970140  0.05
1015   EPI ind5a  0.8952688897  0.8108363769 0.97970140  0.05
1016   EPI ind5a  0.8952688897  0.8108363769 0.97970140  0.05
1017   EPI ind5a  0.8586721048  0.7680670823 0.94927713  0.10
1018   EPI ind5a  0.8586721048  0.7680670823 0.94927713  0.10
1019   EPI ind5a  0.8586721048  0.7680670823 0.94927713  0.10
1020   EPI ind5a  0.8586721048  0.7680670823 0.94927713  0.10
1021   EPI ind5a  0.7298618318  0.6204604001 0.83926326  0.50
1022   EPI ind5a  0.7298618318  0.6204604001 0.83926326  0.50
1023   EPI ind5a  0.7298618318  0.6204604001 0.83926326  0.50
1024   EPI ind5a  0.7298618318  0.6204604001 0.83926326  0.50
1025   EPI ind5a  0.6529513158  0.5276744547 0.77822818  1.00
1026   EPI ind5a  0.6529513158  0.5276744547 0.77822818  1.00
1027   EPI ind5a  0.6529513158  0.5276744547 0.77822818  1.00
1028   EPI ind5a  0.6529513158  0.5276744547 0.77822818  1.00
1029   EPI ind5a  0.4324582683  0.2850973556 0.57981918  5.00
1030   EPI ind5a  0.4324582683  0.2850973556 0.57981918  5.00
1031   EPI ind5a  0.4324582683  0.2850973556 0.57981918  5.00
1032   EPI ind5a  0.4324582683  0.2850973556 0.57981918  5.00
1033   EPI ind5a  0.3287646494  0.1943081026 0.46322120 10.00
1034   EPI ind5a  0.3287646494  0.1943081026 0.46322120 10.00
1035   EPI ind5a  0.3287646494  0.1943081026 0.46322120 10.00
1036   EPI ind5a  0.3287646494  0.1943081026 0.46322120 10.00
1037   EPI ind5a  0.1058340505 -0.1275008160 0.33916892 50.00
1038   EPI ind5a  0.1058340505 -0.1275008160 0.33916892 50.00
1039   EPI ind5a  0.1058340505 -0.1275008160 0.33916892 50.00
1040   EPI ind5a  0.1058340505 -0.1275008160 0.33916892 50.00
1041   EPI ind5b  0.9690161825  0.9171750373 1.02085733  0.01
1042   EPI ind5b  0.9690161825  0.9171750373 1.02085733  0.01
1043   EPI ind5b  0.9690161825  0.9171750373 1.02085733  0.01
1044   EPI ind5b  0.9690161825  0.9171750373 1.02085733  0.01
1045   EPI ind5b  0.9230309799  0.8405008968 1.00556106  0.05
1046   EPI ind5b  0.9230309799  0.8405008968 1.00556106  0.05
1047   EPI ind5b  0.9230309799  0.8405008968 1.00556106  0.05
1048   EPI ind5b  0.9230309799  0.8405008968 1.00556106  0.05
1049   EPI ind5b  0.8878027992  0.7931903356 0.98241526  0.10
1050   EPI ind5b  0.8878027992  0.7931903356 0.98241526  0.10
1051   EPI ind5b  0.8878027992  0.7931903356 0.98241526  0.10
1052   EPI ind5b  0.8878027992  0.7931903356 0.98241526  0.10
1053   EPI ind5b  0.7479868368  0.6306332365 0.86534044  0.50
1054   EPI ind5b  0.7479868368  0.6306332365 0.86534044  0.50
1055   EPI ind5b  0.7479868368  0.6306332365 0.86534044  0.50
1056   EPI ind5b  0.7479868368  0.6306332365 0.86534044  0.50
1057   EPI ind5b  0.6577614712  0.5251752284 0.79034771  1.00
1058   EPI ind5b  0.6577614712  0.5251752284 0.79034771  1.00
1059   EPI ind5b  0.6577614712  0.5251752284 0.79034771  1.00
1060   EPI ind5b  0.6577614712  0.5251752284 0.79034771  1.00
1061   EPI ind5b  0.3953650097  0.2364324854 0.55429753  5.00
1062   EPI ind5b  0.3953650097  0.2364324854 0.55429753  5.00
1063   EPI ind5b  0.3953650097  0.2364324854 0.55429753  5.00
1064   EPI ind5b  0.3953650097  0.2364324854 0.55429753  5.00
1065   EPI ind5b  0.2783052478  0.1337185123 0.42289198 10.00
1066   EPI ind5b  0.2783052478  0.1337185123 0.42289198 10.00
1067   EPI ind5b  0.2783052478  0.1337185123 0.42289198 10.00
1068   EPI ind5b  0.2783052478  0.1337185123 0.42289198 10.00
1069   EPI ind5b  0.0570042522 -0.1820804639 0.29608897 50.00
1070   EPI ind5b  0.0570042522 -0.1820804639 0.29608897 50.00
1071   EPI ind5b  0.0570042522 -0.1820804639 0.29608897 50.00
1072   EPI ind5b  0.0570042522 -0.1820804639 0.29608897 50.00
1073   EPI ind6a  0.9628689459  0.9191983654 1.00653953  0.01
1074   EPI ind6a  0.9628689459  0.9191983654 1.00653953  0.01
1075   EPI ind6a  0.9628689459  0.9191983654 1.00653953  0.01
1076   EPI ind6a  0.9628689459  0.9191983654 1.00653953  0.01
1077   EPI ind6a  0.9056544860  0.8374422372 0.97386673  0.05
1078   EPI ind6a  0.9056544860  0.8374422372 0.97386673  0.05
1079   EPI ind6a  0.9056544860  0.8374422372 0.97386673  0.05
1080   EPI ind6a  0.9056544860  0.8374422372 0.97386673  0.05
1081   EPI ind6a  0.8618298401  0.7867444432 0.93691524  0.10
1082   EPI ind6a  0.8618298401  0.7867444432 0.93691524  0.10
1083   EPI ind6a  0.8618298401  0.7867444432 0.93691524  0.10
1084   EPI ind6a  0.8618298401  0.7867444432 0.93691524  0.10
1085   EPI ind6a  0.6927191633  0.6218915376 0.76354679  0.50
1086   EPI ind6a  0.6927191633  0.6218915376 0.76354679  0.50
1087   EPI ind6a  0.6927191633  0.6218915376 0.76354679  0.50
1088   EPI ind6a  0.6927191633  0.6218915376 0.76354679  0.50
1089   EPI ind6a  0.5892311973  0.5187007153 0.65976168  1.00
1090   EPI ind6a  0.5892311973  0.5187007153 0.65976168  1.00
1091   EPI ind6a  0.5892311973  0.5187007153 0.65976168  1.00
1092   EPI ind6a  0.5892311973  0.5187007153 0.65976168  1.00
1093   EPI ind6a  0.3165036944  0.2305219950 0.40248539  5.00
1094   EPI ind6a  0.3165036944  0.2305219950 0.40248539  5.00
1095   EPI ind6a  0.3165036944  0.2305219950 0.40248539  5.00
1096   EPI ind6a  0.3165036944  0.2305219950 0.40248539  5.00
1097   EPI ind6a  0.2083041351  0.1282863913 0.28832188 10.00
1098   EPI ind6a  0.2083041351  0.1282863913 0.28832188 10.00
1099   EPI ind6a  0.2083041351  0.1282863913 0.28832188 10.00
1100   EPI ind6a  0.2083041351  0.1282863913 0.28832188 10.00
1101   EPI ind6a  0.0255396104 -0.0950178728 0.14609709 50.00
1102   EPI ind6a  0.0255396104 -0.0950178728 0.14609709 50.00
1103   EPI ind6a  0.0255396104 -0.0950178728 0.14609709 50.00
1104   EPI ind6a  0.0255396104 -0.0950178728 0.14609709 50.00
1105   EPI ind6b  0.9994736198  0.9953915805 1.00355566  0.01
1106   EPI ind6b  0.9994736198  0.9953915805 1.00355566  0.01
1107   EPI ind6b  0.9994736198  0.9953915805 1.00355566  0.01
1108   EPI ind6b  0.9994736198  0.9953915805 1.00355566  0.01
1109   EPI ind6b  0.9897581148  0.9426657590 1.03685047  0.05
1110   EPI ind6b  0.9897581148  0.9426657590 1.03685047  0.05
1111   EPI ind6b  0.9897581148  0.9426657590 1.03685047  0.05
1112   EPI ind6b  0.9897581148  0.9426657590 1.03685047  0.05
1113   EPI ind6b  0.9641766370  0.8496678064 1.07868547  0.10
1114   EPI ind6b  0.9641766370  0.8496678064 1.07868547  0.10
1115   EPI ind6b  0.9641766370  0.8496678064 1.07868547  0.10
1116   EPI ind6b  0.9641766370  0.8496678064 1.07868547  0.10
1117   EPI ind6b  0.6070726499  0.4267253890 0.78741991  0.50
1118   EPI ind6b  0.6070726499  0.4267253890 0.78741991  0.50
1119   EPI ind6b  0.6070726499  0.4267253890 0.78741991  0.50
1120   EPI ind6b  0.6070726499  0.4267253890 0.78741991  0.50
1121   EPI ind6b  0.3603914735  0.1526527438 0.56813020  1.00
1122   EPI ind6b  0.3603914735  0.1526527438 0.56813020  1.00
1123   EPI ind6b  0.3603914735  0.1526527438 0.56813020  1.00
1124   EPI ind6b  0.3603914735  0.1526527438 0.56813020  1.00
1125   EPI ind6b  0.1710256740  0.0510772238 0.29097412  5.00
1126   EPI ind6b  0.1710256740  0.0510772238 0.29097412  5.00
1127   EPI ind6b  0.1710256740  0.0510772238 0.29097412  5.00
1128   EPI ind6b  0.1710256740  0.0510772238 0.29097412  5.00
1129   EPI ind6b  0.1614200586  0.0301492715 0.29269085 10.00
1130   EPI ind6b  0.1614200586  0.0301492715 0.29269085 10.00
1131   EPI ind6b  0.1614200586  0.0301492715 0.29269085 10.00
1132   EPI ind6b  0.1614200586  0.0301492715 0.29269085 10.00
1133   EPI ind6b  0.1578694710  0.0172101361 0.29852881 50.00
1134   EPI ind6b  0.1578694710  0.0172101361 0.29852881 50.00
1135   EPI ind6b  0.1578694710  0.0172101361 0.29852881 50.00
1136   EPI ind6b  0.1578694710  0.0172101361 0.29852881 50.00
1137   MTX ind1a  0.9999999497  0.9999991476 1.00000075  0.01
1138   MTX ind1a  0.9999999497  0.9999991476 1.00000075  0.01
1139   MTX ind1a  0.9999999497  0.9999991476 1.00000075  0.01
1140   MTX ind1a  0.9999999497  0.9999991476 1.00000075  0.01
1141   MTX ind1a  0.9999810981  0.9997862222 1.00017597  0.05
1142   MTX ind1a  0.9999810981  0.9997862222 1.00017597  0.05
1143   MTX ind1a  0.9999810981  0.9997862222 1.00017597  0.05
1144   MTX ind1a  0.9999810981  0.9997862222 1.00017597  0.05
1145   MTX ind1a  0.9997571212  0.9978423814 1.00167186  0.10
1146   MTX ind1a  0.9997571212  0.9978423814 1.00167186  0.10
1147   MTX ind1a  0.9997571212  0.9978423814 1.00167186  0.10
1148   MTX ind1a  0.9997571212  0.9978423814 1.00167186  0.10
1149   MTX ind1a  0.9163894669  0.7390211566 1.09375778  0.50
1150   MTX ind1a  0.9163894669  0.7390211566 1.09375778  0.50
1151   MTX ind1a  0.9163894669  0.7390211566 1.09375778  0.50
1152   MTX ind1a  0.9163894669  0.7390211566 1.09375778  0.50
1153   MTX ind1a  0.4622414510  0.2838554747 0.64062743  1.00
1154   MTX ind1a  0.4622414510  0.2838554747 0.64062743  1.00
1155   MTX ind1a  0.4622414510  0.2838554747 0.64062743  1.00
1156   MTX ind1a  0.4622414510  0.2838554747 0.64062743  1.00
1157   MTX ind1a  0.0095394368 -0.0930057864 0.11208466  5.00
1158   MTX ind1a  0.0095394368 -0.0930057864 0.11208466  5.00
1159   MTX ind1a  0.0095394368 -0.0930057864 0.11208466  5.00
1160   MTX ind1a  0.0095394368 -0.0930057864 0.11208466  5.00
1161   MTX ind1a  0.0074837122 -0.0959772210 0.11094465 10.00
1162   MTX ind1a  0.0074837122 -0.0959772210 0.11094465 10.00
1163   MTX ind1a  0.0074837122 -0.0959772210 0.11094465 10.00
1164   MTX ind1a  0.0074837122 -0.0959772210 0.11094465 10.00
1165   MTX ind1a  0.0073103397 -0.0963298859 0.11095057 50.00
1166   MTX ind1a  0.0073103397 -0.0963298859 0.11095057 50.00
1167   MTX ind1a  0.0073103397 -0.0963298859 0.11095057 50.00
1168   MTX ind1a  0.0073103397 -0.0963298859 0.11095057 50.00
1169   MTX ind1b  0.9924705403  0.9538380854 1.03110300  0.01
1170   MTX ind1b  0.9924705403  0.9538380854 1.03110300  0.01
1171   MTX ind1b  0.9924705403  0.9538380854 1.03110300  0.01
1172   MTX ind1b  0.9629454895  0.8378425188 1.08804846  0.05
1173   MTX ind1b  0.9629454895  0.8378425188 1.08804846  0.05
1174   MTX ind1b  0.9629454895  0.8378425188 1.08804846  0.05
1175   MTX ind1b  0.9629454895  0.8378425188 1.08804846  0.05
1176   MTX ind1b  0.9279818460  0.7403228226 1.11564087  0.10
1177   MTX ind1b  0.9279818460  0.7403228226 1.11564087  0.10
1178   MTX ind1b  0.9279818460  0.7403228226 1.11564087  0.10
1179   MTX ind1b  0.9279818460  0.7403228226 1.11564087  0.10
1180   MTX ind1b  0.7125195863  0.4417207720 0.98331840  0.50
1181   MTX ind1b  0.7125195863  0.4417207720 0.98331840  0.50
1182   MTX ind1b  0.7125195863  0.4417207720 0.98331840  0.50
1183   MTX ind1b  0.7125195863  0.4417207720 0.98331840  0.50
1184   MTX ind1b  0.5433881971  0.3252862414 0.76149015  1.00
1185   MTX ind1b  0.5433881971  0.3252862414 0.76149015  1.00
1186   MTX ind1b  0.5433881971  0.3252862414 0.76149015  1.00
1187   MTX ind1b  0.5433881971  0.3252862414 0.76149015  1.00
1188   MTX ind1b  0.1428219637 -0.0677185419 0.35336247  5.00
1189   MTX ind1b  0.1428219637 -0.0677185419 0.35336247  5.00
1190   MTX ind1b  0.1428219637 -0.0677185419 0.35336247  5.00
1191   MTX ind1b  0.1428219637 -0.0677185419 0.35336247  5.00
1192   MTX ind1b  0.0383790505 -0.1518616928 0.22861979 10.00
1193   MTX ind1b  0.0383790505 -0.1518616928 0.22861979 10.00
1194   MTX ind1b  0.0383790505 -0.1518616928 0.22861979 10.00
1195   MTX ind1b  0.0383790505 -0.1518616928 0.22861979 10.00
1196   MTX ind1b -0.0646611504 -0.3032275045 0.17390520 50.00
1197   MTX ind1b -0.0646611504 -0.3032275045 0.17390520 50.00
1198   MTX ind1b -0.0646611504 -0.3032275045 0.17390520 50.00
1199   MTX ind1b -0.0646611504 -0.3032275045 0.17390520 50.00
1200   MTX ind2a  0.9999999803  0.9999996079 1.00000035  0.01
1201   MTX ind2a  0.9999999803  0.9999996079 1.00000035  0.01
1202   MTX ind2a  0.9999999803  0.9999996079 1.00000035  0.01
1203   MTX ind2a  0.9999999803  0.9999996079 1.00000035  0.01
1204   MTX ind2a  0.9999942284  0.9999231589 1.00006530  0.05
1205   MTX ind2a  0.9999942284  0.9999231589 1.00006530  0.05
1206   MTX ind2a  0.9999942284  0.9999231589 1.00006530  0.05
1207   MTX ind2a  0.9999942284  0.9999231589 1.00006530  0.05
1208   MTX ind2a  0.9999333830  0.9993017056 1.00056506  0.10
1209   MTX ind2a  0.9999333830  0.9993017056 1.00056506  0.10
1210   MTX ind2a  0.9999333830  0.9993017056 1.00056506  0.10
1211   MTX ind2a  0.9999333830  0.9993017056 1.00056506  0.10
1212   MTX ind2a  0.9808636760  0.9254216360 1.03630572  0.50
1213   MTX ind2a  0.9808636760  0.9254216360 1.03630572  0.50
1214   MTX ind2a  0.9808636760  0.9254216360 1.03630572  0.50
1215   MTX ind2a  0.9808636760  0.9254216360 1.03630572  0.50
1216   MTX ind2a  0.8161319292  0.7124612306 0.91980263  1.00
1217   MTX ind2a  0.8161319292  0.7124612306 0.91980263  1.00
1218   MTX ind2a  0.8161319292  0.7124612306 0.91980263  1.00
1219   MTX ind2a  0.8161319292  0.7124612306 0.91980263  1.00
1220   MTX ind2a  0.0129663477 -0.0730851834 0.09901788  5.00
1221   MTX ind2a  0.0129663477 -0.0730851834 0.09901788  5.00
1222   MTX ind2a  0.0129663477 -0.0730851834 0.09901788  5.00
1223   MTX ind2a  0.0129663477 -0.0730851834 0.09901788  5.00
1224   MTX ind2a -0.0007147536 -0.0661072659 0.06467776 10.00
1225   MTX ind2a -0.0007147536 -0.0661072659 0.06467776 10.00
1226   MTX ind2a -0.0007147536 -0.0661072659 0.06467776 10.00
1227   MTX ind2a -0.0007147536 -0.0661072659 0.06467776 10.00
1228   MTX ind2a -0.0020276279 -0.0729772678 0.06892201 50.00
1229   MTX ind2a -0.0020276279 -0.0729772678 0.06892201 50.00
1230   MTX ind2a -0.0020276279 -0.0729772678 0.06892201 50.00
1231   MTX ind2a -0.0020276279 -0.0729772678 0.06892201 50.00
1232   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.01
1233   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.01
1234   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.01
1235   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.01
1236   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.05
1237   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.05
1238   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.05
1239   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.05
1240   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.10
1241   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.10
1242   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.10
1243   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.10
1244   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
1245   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
1246   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
1247   MTX ind2b  1.0000000000  1.0000000000 1.00000000  0.50
1248   MTX ind2b  1.0000000000  1.0000000000 1.00000000  1.00
1249   MTX ind2b  1.0000000000  1.0000000000 1.00000000  1.00
1250   MTX ind2b  1.0000000000  1.0000000000 1.00000000  1.00
1251   MTX ind2b  1.0000000000  1.0000000000 1.00000000  1.00
1252   MTX ind2b  0.0182391215 -0.1912610395 0.22773928  5.00
1253   MTX ind2b  0.0182391215 -0.1912610395 0.22773928  5.00
1254   MTX ind2b  0.0182391215 -0.1912610395 0.22773928  5.00
1255   MTX ind2b  0.0182391215 -0.1912610395 0.22773928  5.00
1256   MTX ind2b  0.0077094365 -0.1410663145 0.15648519 10.00
1257   MTX ind2b  0.0077094365 -0.1410663145 0.15648519 10.00
1258   MTX ind2b  0.0077094365 -0.1410663145 0.15648519 10.00
1259   MTX ind2b  0.0077094365 -0.1410663145 0.15648519 10.00
1260   MTX ind2b  0.0077094361 -0.1410663310 0.15648520 50.00
1261   MTX ind2b  0.0077094361 -0.1410663310 0.15648520 50.00
1262   MTX ind2b  0.0077094361 -0.1410663310 0.15648520 50.00
1263   MTX ind2b  0.0077094361 -0.1410663310 0.15648520 50.00
1264   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.01
1265   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.01
1266   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.01
1267   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.01
1268   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.05
1269   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.05
1270   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.05
1271   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.05
1272   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.10
1273   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.10
1274   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.10
1275   MTX ind3a  1.0000000000  1.0000000000 1.00000000  0.10
1276   MTX ind3a  0.9999988110  0.9994539517 1.00054367  0.50
1277   MTX ind3a  0.9999988110  0.9994539517 1.00054367  0.50
1278   MTX ind3a  0.9999988110  0.9994539517 1.00054367  0.50
1279   MTX ind3a  0.9999988110  0.9994539517 1.00054367  0.50
1280   MTX ind3a  0.3001929117  0.0901991727 0.51018665  1.00
1281   MTX ind3a  0.3001929117  0.0901991727 0.51018665  1.00
1282   MTX ind3a  0.3001929117  0.0901991727 0.51018665  1.00
1283   MTX ind3a  0.3001929117  0.0901991727 0.51018665  1.00
1284   MTX ind3a  0.0366101225 -0.0846297711 0.15785002  5.00
1285   MTX ind3a  0.0366101225 -0.0846297711 0.15785002  5.00
1286   MTX ind3a  0.0366101225 -0.0846297711 0.15785002  5.00
1287   MTX ind3a  0.0366101225 -0.0846297711 0.15785002  5.00
1288   MTX ind3a  0.0366101225 -0.0846297711 0.15785002 10.00
1289   MTX ind3a  0.0366101225 -0.0846297711 0.15785002 10.00
1290   MTX ind3a  0.0366101225 -0.0846297711 0.15785002 10.00
1291   MTX ind3a  0.0366101225 -0.0846297711 0.15785002 10.00
1292   MTX ind3a  0.0366101225 -0.0846297711 0.15785002 50.00
1293   MTX ind3a  0.0366101225 -0.0846297711 0.15785002 50.00
1294   MTX ind3a  0.0366101225 -0.0846297711 0.15785002 50.00
1295   MTX ind3a  0.0366101225 -0.0846297711 0.15785002 50.00
1296   MTX ind3b  1.0000000000           NaN        NaN  0.01
1297   MTX ind3b  1.0000000000           NaN        NaN  0.01
1298   MTX ind3b  1.0000000000           NaN        NaN  0.01
1299   MTX ind3b  1.0000000000           NaN        NaN  0.01
1300   MTX ind3b  1.0000000000           NaN        NaN  0.05
1301   MTX ind3b  1.0000000000           NaN        NaN  0.05
1302   MTX ind3b  1.0000000000           NaN        NaN  0.05
1303   MTX ind3b  1.0000000000           NaN        NaN  0.05
1304   MTX ind3b  1.0000000000           NaN        NaN  0.10
1305   MTX ind3b  1.0000000000           NaN        NaN  0.10
1306   MTX ind3b  1.0000000000           NaN        NaN  0.10
1307   MTX ind3b  1.0000000000           NaN        NaN  0.10
1308   MTX ind3b  1.0000000000           NaN        NaN  0.50
1309   MTX ind3b  1.0000000000           NaN        NaN  0.50
1310   MTX ind3b  1.0000000000           NaN        NaN  0.50
1311   MTX ind3b  1.0000000000           NaN        NaN  0.50
1312   MTX ind3b  0.9999998632           NaN        NaN  1.00
1313   MTX ind3b  0.9999998632           NaN        NaN  1.00
1314   MTX ind3b  0.9999998632           NaN        NaN  1.00
1315   MTX ind3b  0.0287672184 -0.1212742367 0.17880867  5.00
1316   MTX ind3b  0.0287672184 -0.1212742367 0.17880867  5.00
1317   MTX ind3b  0.0287672184 -0.1212742367 0.17880867  5.00
1318   MTX ind3b  0.9999998632           NaN        NaN  1.00
1319   MTX ind3b  0.0287662268 -0.1212818351 0.17881429 10.00
1320   MTX ind3b  0.0287662268 -0.1212818351 0.17881429 10.00
1321   MTX ind3b  0.0287662268 -0.1212818351 0.17881429 10.00
1322   MTX ind3b  0.0287662268 -0.1212818351 0.17881429 10.00
1323   MTX ind3b  0.0287672184 -0.1212742367 0.17880867  5.00
1324   MTX ind3b  0.0287662268 -0.1212818350 0.17881429 50.00
1325   MTX ind3b  0.0287662268 -0.1212818350 0.17881429 50.00
1326   MTX ind3b  0.0287662268 -0.1212818350 0.17881429 50.00
1327   MTX ind3b  0.0287662268 -0.1212818350 0.17881429 50.00
1328   MTX ind4a  0.9999991664  0.9999868775 1.00001146  0.01
1329   MTX ind4a  0.9999991664  0.9999868775 1.00001146  0.01
1330   MTX ind4a  0.9999991664  0.9999868775 1.00001146  0.01
1331   MTX ind4a  0.9999991664  0.9999868775 1.00001146  0.01
1332   MTX ind4a  0.9999204014  0.9991564134 1.00068439  0.05
1333   MTX ind4a  0.9999204014  0.9991564134 1.00068439  0.05
1334   MTX ind4a  0.9999204014  0.9991564134 1.00068439  0.05
1335   MTX ind4a  0.9999204014  0.9991564134 1.00068439  0.05
1336   MTX ind4a  0.9994331942  0.9952483023 1.00361809  0.10
1337   MTX ind4a  0.9994331942  0.9952483023 1.00361809  0.10
1338   MTX ind4a  0.9994331942  0.9952483023 1.00361809  0.10
1339   MTX ind4a  0.9994331942  0.9952483023 1.00361809  0.10
1340   MTX ind4a  0.9486205353  0.8357304796 1.06151059  0.50
1341   MTX ind4a  0.9486205353  0.8357304796 1.06151059  0.50
1342   MTX ind4a  0.9486205353  0.8357304796 1.06151059  0.50
1343   MTX ind4a  0.9486205353  0.8357304796 1.06151059  0.50
1344   MTX ind4a  0.7215269329  0.5777119048 0.86534196  1.00
1345   MTX ind4a  0.7215269329  0.5777119048 0.86534196  1.00
1346   MTX ind4a  0.7215269329  0.5777119048 0.86534196  1.00
1347   MTX ind4a  0.7215269329  0.5777119048 0.86534196  1.00
1348   MTX ind4a  0.0258061561 -0.0923664692 0.14397878  5.00
1349   MTX ind4a  0.0258061561 -0.0923664692 0.14397878  5.00
1350   MTX ind4a  0.0258061561 -0.0923664692 0.14397878  5.00
1351   MTX ind4a  0.0258061561 -0.0923664692 0.14397878  5.00
1352   MTX ind4a  0.0031510989 -0.0875231292 0.09382533 10.00
1353   MTX ind4a  0.0031510989 -0.0875231292 0.09382533 10.00
1354   MTX ind4a  0.0031510989 -0.0875231292 0.09382533 10.00
1355   MTX ind4a  0.0031510989 -0.0875231292 0.09382533 10.00
1356   MTX ind4a -0.0006086453 -0.1031090923 0.10189180 50.00
1357   MTX ind4a -0.0006086453 -0.1031090923 0.10189180 50.00
1358   MTX ind4a -0.0006086453 -0.1031090923 0.10189180 50.00
1359   MTX ind4a -0.0006086453 -0.1031090923 0.10189180 50.00
1360   MTX ind4b  0.8457382337  0.7729309781 0.91854549  0.01
1361   MTX ind4b  0.8457382337  0.7729309781 0.91854549  0.01
1362   MTX ind4b  0.8457382337  0.7729309781 0.91854549  0.01
1363   MTX ind4b  0.8457382337  0.7729309781 0.91854549  0.01
1364   MTX ind4b  0.6842026862  0.6111862017 0.75721917  0.05
1365   MTX ind4b  0.6842026862  0.6111862017 0.75721917  0.05
1366   MTX ind4b  0.6842026862  0.6111862017 0.75721917  0.05
1367   MTX ind4b  0.6842026862  0.6111862017 0.75721917  0.05
1368   MTX ind4b  0.5899068440  0.5224662627 0.65734743  0.10
1369   MTX ind4b  0.5899068440  0.5224662627 0.65734743  0.10
1370   MTX ind4b  0.5899068440  0.5224662627 0.65734743  0.10
1371   MTX ind4b  0.5899068440  0.5224662627 0.65734743  0.10
1372   MTX ind4b  0.3454651201  0.2778844728 0.41304577  0.50
1373   MTX ind4b  0.3454651201  0.2778844728 0.41304577  0.50
1374   MTX ind4b  0.3454651201  0.2778844728 0.41304577  0.50
1375   MTX ind4b  0.3454651201  0.2778844728 0.41304577  0.50
1376   MTX ind4b  0.2468941446  0.1784141810 0.31537411  1.00
1377   MTX ind4b  0.2468941446  0.1784141810 0.31537411  1.00
1378   MTX ind4b  0.2468941446  0.1784141810 0.31537411  1.00
1379   MTX ind4b  0.2468941446  0.1784141810 0.31537411  1.00
1380   MTX ind4b  0.0721252958  0.0115143267 0.13273626  5.00
1381   MTX ind4b  0.0721252958  0.0115143267 0.13273626  5.00
1382   MTX ind4b  0.0721252958  0.0115143267 0.13273626  5.00
1383   MTX ind4b  0.0721252958  0.0115143267 0.13273626  5.00
1384   MTX ind4b  0.0223043584 -0.0418942579 0.08650297 10.00
1385   MTX ind4b  0.0223043584 -0.0418942579 0.08650297 10.00
1386   MTX ind4b  0.0223043584 -0.0418942579 0.08650297 10.00
1387   MTX ind4b  0.0223043584 -0.0418942579 0.08650297 10.00
1388   MTX ind4b -0.0480798727 -0.1406820883 0.04452234 50.00
1389   MTX ind4b -0.0480798727 -0.1406820883 0.04452234 50.00
1390   MTX ind4b -0.0480798727 -0.1406820883 0.04452234 50.00
1391   MTX ind4b -0.0480798727 -0.1406820883 0.04452234 50.00
1392   MTX ind5a  0.9993981282  0.9952155836 1.00358067  0.01
1393   MTX ind5a  0.9993981282  0.9952155836 1.00358067  0.01
1394   MTX ind5a  0.9993981282  0.9952155836 1.00358067  0.01
1395   MTX ind5a  0.9993981282  0.9952155836 1.00358067  0.01
1396   MTX ind5a  0.9918479313  0.9560276460 1.02766822  0.05
1397   MTX ind5a  0.9918479313  0.9560276460 1.02766822  0.05
1398   MTX ind5a  0.9918479313  0.9560276460 1.02766822  0.05
1399   MTX ind5a  0.9918479313  0.9560276460 1.02766822  0.05
1400   MTX ind5a  0.9752871618  0.8945870587 1.05598726  0.10
1401   MTX ind5a  0.9752871618  0.8945870587 1.05598726  0.10
1402   MTX ind5a  0.9752871618  0.8945870587 1.05598726  0.10
1403   MTX ind5a  0.9752871618  0.8945870587 1.05598726  0.10
1404   MTX ind5a  0.7417956865  0.5667732378 0.91681814  0.50
1405   MTX ind5a  0.7417956865  0.5667732378 0.91681814  0.50
1406   MTX ind5a  0.7417956865  0.5667732378 0.91681814  0.50
1407   MTX ind5a  0.7417956865  0.5667732378 0.91681814  0.50
1408   MTX ind5a  0.4786682184  0.3679330072 0.58940343  1.00
1409   MTX ind5a  0.4786682184  0.3679330072 0.58940343  1.00
1410   MTX ind5a  0.4786682184  0.3679330072 0.58940343  1.00
1411   MTX ind5a  0.4786682184  0.3679330072 0.58940343  1.00
1412   MTX ind5a  0.0458341806 -0.0734329902 0.16510135  5.00
1413   MTX ind5a  0.0458341806 -0.0734329902 0.16510135  5.00
1414   MTX ind5a  0.0458341806 -0.0734329902 0.16510135  5.00
1415   MTX ind5a  0.0458341806 -0.0734329902 0.16510135  5.00
1416   MTX ind5a  0.0015512276 -0.0723371055 0.07543956 10.00
1417   MTX ind5a  0.0015512276 -0.0723371055 0.07543956 10.00
1418   MTX ind5a  0.0015512276 -0.0723371055 0.07543956 10.00
1419   MTX ind5a  0.0015512276 -0.0723371055 0.07543956 10.00
1420   MTX ind5a -0.0195107618 -0.1309239254 0.09190240 50.00
1421   MTX ind5a -0.0195107618 -0.1309239254 0.09190240 50.00
1422   MTX ind5a -0.0195107618 -0.1309239254 0.09190240 50.00
1423   MTX ind5a -0.0195107618 -0.1309239254 0.09190240 50.00
1424   MTX ind5b  0.9999999939  0.9999998705 1.00000012  0.01
1425   MTX ind5b  0.9999999939  0.9999998705 1.00000012  0.01
1426   MTX ind5b  0.9999999939  0.9999998705 1.00000012  0.01
1427   MTX ind5b  0.9999948840  0.9999281167 1.00006165  0.05
1428   MTX ind5b  0.9999948840  0.9999281167 1.00006165  0.05
1429   MTX ind5b  0.9999948840  0.9999281167 1.00006165  0.05
1430   MTX ind5b  0.9999948840  0.9999281167 1.00006165  0.05
1431   MTX ind5b  0.9999072250  0.9989803921 1.00083406  0.10
1432   MTX ind5b  0.9999072250  0.9989803921 1.00083406  0.10
1433   MTX ind5b  0.9999072250  0.9989803921 1.00083406  0.10
1434   MTX ind5b  0.9999072250  0.9989803921 1.00083406  0.10
1435   MTX ind5b  0.9280523294  0.7313762682 1.12472839  0.50
1436   MTX ind5b  0.9280523294  0.7313762682 1.12472839  0.50
1437   MTX ind5b  0.9280523294  0.7313762682 1.12472839  0.50
1438   MTX ind5b  0.9280523294  0.7313762682 1.12472839  0.50
1439   MTX ind5b  0.4182019883  0.2224810276 0.61392295  1.00
1440   MTX ind5b  0.4182019883  0.2224810276 0.61392295  1.00
1441   MTX ind5b  0.4182019883  0.2224810276 0.61392295  1.00
1442   MTX ind5b  0.4182019883  0.2224810276 0.61392295  1.00
1443   MTX ind5b  0.0087868738 -0.1038271323 0.12140088  5.00
1444   MTX ind5b  0.0087868738 -0.1038271323 0.12140088  5.00
1445   MTX ind5b  0.0087868738 -0.1038271323 0.12140088  5.00
1446   MTX ind5b  0.0087868738 -0.1038271323 0.12140088  5.00
1447   MTX ind5b  0.0079970148 -0.1051462090 0.12114024 10.00
1448   MTX ind5b  0.0079970148 -0.1051462090 0.12114024 10.00
1449   MTX ind5b  0.0079970148 -0.1051462090 0.12114024 10.00
1450   MTX ind5b  0.0079970148 -0.1051462090 0.12114024 10.00
1451   MTX ind5b  0.0079509376 -0.1052423708 0.12114425 50.00
1452   MTX ind5b  0.0079509376 -0.1052423708 0.12114425 50.00
1453   MTX ind5b  0.0079509376 -0.1052423708 0.12114425 50.00
1454   MTX ind5b  0.0079509376 -0.1052423708 0.12114425 50.00
1455   MTX ind5b  0.9999999939  0.9999998705 1.00000012  0.01
1456   MTX ind6a  0.9999999988  0.9999999529 1.00000004  0.01
1457   MTX ind6a  0.9999999988  0.9999999529 1.00000004  0.01
1458   MTX ind6a  0.9999999988  0.9999999529 1.00000004  0.01
1459   MTX ind6a  0.9999999988  0.9999999529 1.00000004  0.01
1460   MTX ind6a  0.9999988389  0.9999692932 1.00002838  0.05
1461   MTX ind6a  0.9999988389  0.9999692932 1.00002838  0.05
1462   MTX ind6a  0.9999988389  0.9999692932 1.00002838  0.05
1463   MTX ind6a  0.9999988389  0.9999692932 1.00002838  0.05
1464   MTX ind6a  0.9999773608  0.9995348000 1.00041992  0.10
1465   MTX ind6a  0.9999773608  0.9995348000 1.00041992  0.10
1466   MTX ind6a  0.9999773608  0.9995348000 1.00041992  0.10
1467   MTX ind6a  0.9999773608  0.9995348000 1.00041992  0.10
1468   MTX ind6a  0.9780987832  0.8523562098 1.10384136  0.50
1469   MTX ind6a  0.9780987832  0.8523562098 1.10384136  0.50
1470   MTX ind6a  0.9780987832  0.8523562098 1.10384136  0.50
1471   MTX ind6a  0.9780987832  0.8523562098 1.10384136  0.50
1472   MTX ind6a  0.6970814056  0.5652212651 0.82894155  1.00
1473   MTX ind6a  0.6970814056  0.5652212651 0.82894155  1.00
1474   MTX ind6a  0.6970814056  0.5652212651 0.82894155  1.00
1475   MTX ind6a  0.6970814056  0.5652212651 0.82894155  1.00
1476   MTX ind6a  0.0136057905 -0.0648233645 0.09203495  5.00
1477   MTX ind6a  0.0136057905 -0.0648233645 0.09203495  5.00
1478   MTX ind6a  0.0136057905 -0.0648233645 0.09203495  5.00
1479   MTX ind6a  0.0136057905 -0.0648233645 0.09203495  5.00
1480   MTX ind6a  0.0114646860 -0.0654092065 0.08833858 10.00
1481   MTX ind6a  0.0114646860 -0.0654092065 0.08833858 10.00
1482   MTX ind6a  0.0114646860 -0.0654092065 0.08833858 10.00
1483   MTX ind6a  0.0114646860 -0.0654092065 0.08833858 10.00
1484   MTX ind6a  0.0113487981 -0.0658510667 0.08854866 50.00
1485   MTX ind6a  0.0113487981 -0.0658510667 0.08854866 50.00
1486   MTX ind6a  0.0113487981 -0.0658510667 0.08854866 50.00
1487   MTX ind6a  0.0113487981 -0.0658510667 0.08854866 50.00
1488   MTX ind6b  0.9999068719  0.9989328550 1.00088089  0.01
1489   MTX ind6b  0.9999068719  0.9989328550 1.00088089  0.01
1490   MTX ind6b  0.9999068719  0.9989328550 1.00088089  0.01
1491   MTX ind6b  0.9999068719  0.9989328550 1.00088089  0.01
1492   MTX ind6b  0.9977638919  0.9827716296 1.01275615  0.05
1493   MTX ind6b  0.9977638919  0.9827716296 1.01275615  0.05
1494   MTX ind6b  0.9977638919  0.9827716296 1.01275615  0.05
1495   MTX ind6b  0.9977638919  0.9827716296 1.01275615  0.05
1496   MTX ind6b  0.9912582912  0.9469381908 1.03557839  0.10
1497   MTX ind6b  0.9912582912  0.9469381908 1.03557839  0.10
1498   MTX ind6b  0.9912582912  0.9469381908 1.03557839  0.10
1499   MTX ind6b  0.9912582912  0.9469381908 1.03557839  0.10
1500   MTX ind6b  0.8245627539  0.6091505764 1.03997493  0.50
1501   MTX ind6b  0.8245627539  0.6091505764 1.03997493  0.50
1502   MTX ind6b  0.8245627539  0.6091505764 1.03997493  0.50
1503   MTX ind6b  0.8245627539  0.6091505764 1.03997493  0.50
1504   MTX ind6b  0.5422852310  0.3733676863 0.71120278  1.00
1505   MTX ind6b  0.5422852310  0.3733676863 0.71120278  1.00
1506   MTX ind6b  0.5422852310  0.3733676863 0.71120278  1.00
1507   MTX ind6b  0.5422852310  0.3733676863 0.71120278  1.00
1508   MTX ind6b  0.0354008155 -0.1133165503 0.18411818  5.00
1509   MTX ind6b  0.0354008155 -0.1133165503 0.18411818  5.00
1510   MTX ind6b  0.0354008155 -0.1133165503 0.18411818  5.00
1511   MTX ind6b  0.0354008155 -0.1133165503 0.18411818  5.00
1512   MTX ind6b -0.0004298083 -0.1114533951 0.11059378 10.00
1513   MTX ind6b -0.0004298083 -0.1114533951 0.11059378 10.00
1514   MTX ind6b -0.0004298083 -0.1114533951 0.11059378 10.00
1515   MTX ind6b -0.0004298083 -0.1114533951 0.11059378 10.00
1516   MTX ind6b -0.0127155824 -0.1534288455 0.12799768 50.00
1517   MTX ind6b -0.0127155824 -0.1534288455 0.12799768 50.00
1518   MTX ind6b -0.0127155824 -0.1534288455 0.12799768 50.00
1519   MTX ind6b -0.0127155824 -0.1534288455 0.12799768 50.00
1520   TRZ ind1a  0.9007886908  0.8118036029 0.98977378  0.01
1521   TRZ ind1a  0.9007886908  0.8118036029 0.98977378  0.01
1522   TRZ ind1a  0.9007886908  0.8118036029 0.98977378  0.01
1523   TRZ ind1a  0.9007886908  0.8118036029 0.98977378  0.01
1524   TRZ ind1a  0.9005740366  0.8118519567 0.98929612  0.05
1525   TRZ ind1a  0.9005740366  0.8118519567 0.98929612  0.05
1526   TRZ ind1a  0.9005740366  0.8118519567 0.98929612  0.05
1527   TRZ ind1a  0.9005740366  0.8118519567 0.98929612  0.05
1528   TRZ ind1a  0.9003051719  0.8119099572 0.98870039  0.10
1529   TRZ ind1a  0.9003051719  0.8119099572 0.98870039  0.10
1530   TRZ ind1a  0.9003051719  0.8119099572 0.98870039  0.10
1531   TRZ ind1a  0.9003051719  0.8119099572 0.98870039  0.10
1532   TRZ ind1a  0.8981322952  0.8122649536 0.98399964  0.50
1533   TRZ ind1a  0.8981322952  0.8122649536 0.98399964  0.50
1534   TRZ ind1a  0.8981322952  0.8122649536 0.98399964  0.50
1535   TRZ ind1a  0.8981322952  0.8122649536 0.98399964  0.50
1536   TRZ ind1a  0.8953608915  0.8123756670 0.97834612  1.00
1537   TRZ ind1a  0.8953608915  0.8123756670 0.97834612  1.00
1538   TRZ ind1a  0.8953608915  0.8123756670 0.97834612  1.00
1539   TRZ ind1a  0.8953608915  0.8123756670 0.97834612  1.00
1540   TRZ ind1a  0.8709024379  0.7840317398 0.95777314  5.00
1541   TRZ ind1a  0.8709024379  0.7840317398 0.95777314  5.00
1542   TRZ ind1a  0.8709024379  0.7840317398 0.95777314  5.00
1543   TRZ ind1a  0.8709024379  0.7840317398 0.95777314  5.00
1544   TRZ ind1a  0.8343683450  0.6425573835 1.02617931 10.00
1545   TRZ ind1a  0.8343683450  0.6425573835 1.02617931 10.00
1546   TRZ ind1a  0.8343683450  0.6425573835 1.02617931 10.00
1547   TRZ ind1a  0.8343683450  0.6425573835 1.02617931 10.00
1548   TRZ ind1b  0.9267760781  0.7132418215 1.14031033  0.01
1549   TRZ ind1b  0.9267760781  0.7132418215 1.14031033  0.01
1550   TRZ ind1b  0.9267760781  0.7132418215 1.14031033  0.01
1551   TRZ ind1b  0.9267760781  0.7132418215 1.14031033  0.01
1552   TRZ ind1b  0.9282220957  0.7211957881 1.13524840  0.05
1553   TRZ ind1b  0.9282220957  0.7211957881 1.13524840  0.05
1554   TRZ ind1b  0.9282220957  0.7211957881 1.13524840  0.05
1555   TRZ ind1b  0.9282220957  0.7211957881 1.13524840  0.05
1556   TRZ ind1b  0.9299941666  0.7303759785 1.12961235  0.10
1557   TRZ ind1b  0.9299941666  0.7303759785 1.12961235  0.10
1558   TRZ ind1b  0.9299941666  0.7303759785 1.12961235  0.10
1559   TRZ ind1b  0.9299941666  0.7303759785 1.12961235  0.10
1560   TRZ ind1b  0.9428244095  0.7759854152 1.10966340  0.50
1561   TRZ ind1b  0.9428244095  0.7759854152 1.10966340  0.50
1562   TRZ ind1b  0.9428244095  0.7759854152 1.10966340  0.50
1563   TRZ ind1b  0.9428244095  0.7759854152 1.10966340  0.50
1564   TRZ ind1b  0.9558445085  0.7891375721 1.12255144  1.00
1565   TRZ ind1b  0.9558445085  0.7891375721 1.12255144  1.00
1566   TRZ ind1b  0.9558445085  0.7891375721 1.12255144  1.00
1567   TRZ ind1b  0.9558445085  0.7891375721 1.12255144  1.00
1568   TRZ ind1b  0.9949753490  0.9115979289 1.07835277  5.00
1569   TRZ ind1b  0.9949753490  0.9115979289 1.07835277  5.00
1570   TRZ ind1b  0.9949753490  0.9115979289 1.07835277  5.00
1571   TRZ ind1b  0.9949753490  0.9115979289 1.07835277  5.00
1572   TRZ ind1b  0.9996896992  0.9896049374 1.00977446 10.00
1573   TRZ ind1b  0.9996896992  0.9896049374 1.00977446 10.00
1574   TRZ ind2a  0.9219307140  0.8653473975 0.97851403  0.01
1575   TRZ ind2a  0.9219307140  0.8653473975 0.97851403  0.01
1576   TRZ ind2a  0.9219307140  0.8653473975 0.97851403  0.01
1577   TRZ ind2a  0.9219307140  0.8653473975 0.97851403  0.01
1578   TRZ ind2a  0.9218528810  0.8656217993 0.97808396  0.05
1579   TRZ ind2a  0.9218528810  0.8656217993 0.97808396  0.05
1580   TRZ ind2a  0.9218528810  0.8656217993 0.97808396  0.05
1581   TRZ ind2a  0.9218528810  0.8656217993 0.97808396  0.05
1582   TRZ ind2a  0.9217555894  0.8659609199 0.97755026  0.10
1583   TRZ ind2a  0.9217555894  0.8659609199 0.97755026  0.10
1584   TRZ ind2a  0.9217555894  0.8659609199 0.97755026  0.10
1585   TRZ ind2a  0.9217555894  0.8659609199 0.97755026  0.10
1586   TRZ ind2a  0.9209772766  0.8685014595 0.97345309  0.50
1587   TRZ ind2a  0.9209772766  0.8685014595 0.97345309  0.50
1588   TRZ ind2a  0.9209772766  0.8685014595 0.97345309  0.50
1589   TRZ ind2a  0.9209772766  0.8685014595 0.97345309  0.50
1590   TRZ ind2a  0.9200046076  0.8711536339 0.96885558  1.00
1591   TRZ ind2a  0.9200046076  0.8711536339 0.96885558  1.00
1592   TRZ ind2a  0.9200046076  0.8711536339 0.96885558  1.00
1593   TRZ ind2a  0.9200046076  0.8711536339 0.96885558  1.00
1594   TRZ ind2a  0.9122672017  0.8555399476 0.96899446  5.00
1595   TRZ ind2a  0.9122672017  0.8555399476 0.96899446  5.00
1596   TRZ ind2a  0.9122672017  0.8555399476 0.96899446  5.00
1597   TRZ ind2a  0.9122672017  0.8555399476 0.96899446  5.00
1598   TRZ ind2a  0.9028688036  0.7763902945 1.02934731 10.00
1599   TRZ ind2a  0.9028688036  0.7763902945 1.02934731 10.00
1600   TRZ ind2a  0.9028688036  0.7763902945 1.02934731 10.00
1601   TRZ ind2a  0.9028688036  0.7763902945 1.02934731 10.00
1602   TRZ ind2b  0.9486538703  0.7899761138 1.10733163  0.01
1603   TRZ ind2b  0.9486538703  0.7899761138 1.10733163  0.01
1604   TRZ ind2b  0.9486538703  0.7899761138 1.10733163  0.01
1605   TRZ ind2b  0.9486538703  0.7899761138 1.10733163  0.01
1606   TRZ ind2b  0.9490764034  0.7913565927 1.10679621  0.05
1607   TRZ ind2b  0.9490764034  0.7913565927 1.10679621  0.05
1608   TRZ ind2b  0.9490764034  0.7913565927 1.10679621  0.05
1609   TRZ ind2b  0.9490764034  0.7913565927 1.10679621  0.05
1610   TRZ ind2b  0.9495999427  0.7934775217 1.10572236  0.10
1611   TRZ ind2b  0.9495999427  0.7934775217 1.10572236  0.10
1612   TRZ ind2b  0.9495999427  0.7934775217 1.10572236  0.10
1613   TRZ ind2b  0.9495999427  0.7934775217 1.10572236  0.10
1614   TRZ ind2b  0.9536083114  0.8227399396 1.08447668  0.50
1615   TRZ ind2b  0.9536083114  0.8227399396 1.08447668  0.50
1616   TRZ ind2b  0.9536083114  0.8227399396 1.08447668  0.50
1617   TRZ ind2b  0.9536083114  0.8227399396 1.08447668  0.50
1618   TRZ ind2b  0.9581930702  0.8838120123 1.03257413  1.00
1619   TRZ ind2b  0.9581930702  0.8838120123 1.03257413  1.00
1620   TRZ ind2b  0.9581930702  0.8838120123 1.03257413  1.00
1621   TRZ ind2b  0.9581930702  0.8838120123 1.03257413  1.00
1622   TRZ ind2b  0.9820631860  0.9561982989 1.00792807  5.00
1623   TRZ ind2b  0.9820631860  0.9561982989 1.00792807  5.00
1624   TRZ ind2b  0.9820631860  0.9561982989 1.00792807  5.00
1625   TRZ ind2b  0.9820631860  0.9561982989 1.00792807  5.00
1626   TRZ ind2b  0.9938874920  0.9087657494 1.07900923 10.00
1627   TRZ ind2b  0.9938874920  0.9087657494 1.07900923 10.00
1628   TRZ ind2b  0.9938874920  0.9087657494 1.07900923 10.00
1629   TRZ ind2b  0.9938874920  0.9087657494 1.07900923 10.00
1630   TRZ ind3a  1.1789806398  0.9545556439 1.40340564  0.01
1631   TRZ ind3a  1.1789806398  0.9545556439 1.40340564  0.01
1632   TRZ ind3a  1.1789806398  0.9545556439 1.40340564  0.01
1633   TRZ ind3a  1.1789806398  0.9545556439 1.40340564  0.01
1634   TRZ ind3a  1.1731026414  0.9809792274 1.36522606  0.05
1635   TRZ ind3a  1.1731026414  0.9809792274 1.36522606  0.05
1636   TRZ ind3a  1.1731026414  0.9809792274 1.36522606  0.05
1637   TRZ ind3a  1.1731026414  0.9809792274 1.36522606  0.05
1638   TRZ ind3a  1.1657019785  1.0212831364 1.31012082  0.10
1639   TRZ ind3a  1.1657019785  1.0212831364 1.31012082  0.10
1640   TRZ ind3a  1.1657019785  1.0212831364 1.31012082  0.10
1641   TRZ ind3a  1.1657019785  1.0212831364 1.31012082  0.10
1642   TRZ ind3a  1.1080886538           NaN        NaN  0.50
1643   TRZ ind3a  1.1080886538           NaN        NaN  0.50
1644   TRZ ind3a  1.1080886538           NaN        NaN  0.50
1645   TRZ ind3a  1.1080886538           NaN        NaN  0.50
1646   TRZ ind3a  1.0534681267  0.9165223706 1.19041388  1.00
1647   TRZ ind3a  1.0534681267  0.9165223706 1.19041388  1.00
1648   TRZ ind3a  1.0534681267  0.9165223706 1.19041388  1.00
1649   TRZ ind3a  1.0534681267  0.9165223706 1.19041388  1.00
1650   TRZ ind3a  1.0000362149           NaN        NaN  5.00
1651   TRZ ind3a  1.0000362149           NaN        NaN  5.00
1652   TRZ ind3a  1.0000362149           NaN        NaN  5.00
1653   TRZ ind3a  1.0000362149           NaN        NaN  5.00
1654   TRZ ind3a  1.0000000031           NaN        NaN 10.00
1655   TRZ ind3a  1.0000000031           NaN        NaN 10.00
1656   TRZ ind3a  1.0000000031           NaN        NaN 10.00
1657   TRZ ind3a  1.0000000031           NaN        NaN 10.00
1658   TRZ ind3b  0.9999510302  0.9973259972 1.00257606  0.01
1659   TRZ ind3b  0.9999510302  0.9973259972 1.00257606  0.01
1660   TRZ ind3b  0.9999510302  0.9973259972 1.00257606  0.01
1661   TRZ ind3b  0.9999485966  0.9972155671 1.00268163  0.05
1662   TRZ ind3b  0.9999485966  0.9972155671 1.00268163  0.05
1663   TRZ ind3b  0.9999485966  0.9972155671 1.00268163  0.05
1664   TRZ ind3b  0.9999485966  0.9972155671 1.00268163  0.05
1665   TRZ ind3b  0.9999453837  0.9970713456 1.00281942  0.10
1666   TRZ ind3b  0.9999453837  0.9970713456 1.00281942  0.10
1667   TRZ ind3b  0.9999453837  0.9970713456 1.00281942  0.10
1668   TRZ ind3b  0.9999453837  0.9970713456 1.00281942  0.10
1669   TRZ ind3b  0.9999112944  0.9956294263 1.00419316  0.50
1670   TRZ ind3b  0.9999112944  0.9956294263 1.00419316  0.50
1671   TRZ ind3b  0.9999112944  0.9956294263 1.00419316  0.50
1672   TRZ ind3b  0.9998373708  0.9928643136 1.00681043  1.00
1673   TRZ ind3b  0.9998373708  0.9928643136 1.00681043  1.00
1674   TRZ ind3b  0.9998373708  0.9928643136 1.00681043  1.00
1675   TRZ ind3b  0.9998373708  0.9928643136 1.00681043  1.00
1676   TRZ ind3b  0.9803591423  0.7161157836 1.24460250  5.00
1677   TRZ ind3b  0.9803591423  0.7161157836 1.24460250  5.00
1678   TRZ ind3b  0.9803591423  0.7161157836 1.24460250  5.00
1679   TRZ ind3b  0.9803591423  0.7161157836 1.24460250  5.00
1680   TRZ ind3b  0.6615134167  0.4086790551 0.91434778 10.00
1681   TRZ ind3b  0.6615134167  0.4086790551 0.91434778 10.00
1682   TRZ ind3b  0.6615134167  0.4086790551 0.91434778 10.00
1683   TRZ ind3b  0.6615134167  0.4086790551 0.91434778 10.00
1684   TRZ ind4a  0.9467038103  0.8414232726 1.05198435  0.01
1685   TRZ ind4a  0.9467038103  0.8414232726 1.05198435  0.01
1686   TRZ ind4a  0.9467038103  0.8414232726 1.05198435  0.01
1687   TRZ ind4a  0.9467038103  0.8414232726 1.05198435  0.01
1688   TRZ ind4a  0.9464863934  0.8413261097 1.05164668  0.05
1689   TRZ ind4a  0.9464863934  0.8413261097 1.05164668  0.05
1690   TRZ ind4a  0.9464863934  0.8413261097 1.05164668  0.05
1691   TRZ ind4a  0.9464863934  0.8413261097 1.05164668  0.05
1692   TRZ ind4a  0.9462134358  0.8412057920 1.05122108  0.10
1693   TRZ ind4a  0.9462134358  0.8412057920 1.05122108  0.10
1694   TRZ ind4a  0.9462134358  0.8412057920 1.05122108  0.10
1695   TRZ ind4a  0.9462134358  0.8412057920 1.05122108  0.10
1696   TRZ ind4a  0.9439816409  0.8402851897 1.04767809  0.50
1697   TRZ ind4a  0.9439816409  0.8402851897 1.04767809  0.50
1698   TRZ ind4a  0.9439816409  0.8402851897 1.04767809  0.50
1699   TRZ ind4a  0.9439816409  0.8402851897 1.04767809  0.50
1700   TRZ ind4a  0.9410682454  0.8392174845 1.04291901  1.00
1701   TRZ ind4a  0.9410682454  0.8392174845 1.04291901  1.00
1702   TRZ ind4a  0.9410682454  0.8392174845 1.04291901  1.00
1703   TRZ ind4a  0.9410682454  0.8392174845 1.04291901  1.00
1704   TRZ ind4a  0.9120828215  0.8200605526 1.00410509  5.00
1705   TRZ ind4a  0.9120828215  0.8200605526 1.00410509  5.00
1706   TRZ ind4a  0.9120828215  0.8200605526 1.00410509  5.00
1707   TRZ ind4a  0.9120828215  0.8200605526 1.00410509  5.00
1708   TRZ ind4a  0.8577522951  0.6262859251 1.08921867 10.00
1709   TRZ ind4a  0.8577522951  0.6262859251 1.08921867 10.00
1710   TRZ ind4a  0.8577522951  0.6262859251 1.08921867 10.00
1711   TRZ ind4a  0.8577522951  0.6262859251 1.08921867 10.00
1712   TRZ ind4b  0.8880213668  0.8113634034 0.96467933  0.01
1713   TRZ ind4b  0.8880213668  0.8113634034 0.96467933  0.01
1714   TRZ ind4b  0.8880213668  0.8113634034 0.96467933  0.01
1715   TRZ ind4b  0.8880213668  0.8113634034 0.96467933  0.01
1716   TRZ ind4b  0.8876342666  0.8110920312 0.96417650  0.05
1717   TRZ ind4b  0.8876342666  0.8110920312 0.96417650  0.05
1718   TRZ ind4b  0.8876342666  0.8110920312 0.96417650  0.05
1719   TRZ ind4b  0.8876342666  0.8110920312 0.96417650  0.05
1720   TRZ ind4b  0.8871487400  0.8107500139 0.96354747  0.10
1721   TRZ ind4b  0.8871487400  0.8107500139 0.96354747  0.10
1722   TRZ ind4b  0.8871487400  0.8107500139 0.96354747  0.10
1723   TRZ ind4b  0.8871487400  0.8107500139 0.96354747  0.10
1724   TRZ ind4b  0.8831979245  0.8078947302 0.95850112  0.50
1725   TRZ ind4b  0.8831979245  0.8078947302 0.95850112  0.50
1726   TRZ ind4b  0.8831979245  0.8078947302 0.95850112  0.50
1727   TRZ ind4b  0.8831979245  0.8078947302 0.95850112  0.50
1728   TRZ ind4b  0.8780902292  0.8039915698 0.95218889  1.00
1729   TRZ ind4b  0.8780902292  0.8039915698 0.95218889  1.00
1730   TRZ ind4b  0.8780902292  0.8039915698 0.95218889  1.00
1731   TRZ ind4b  0.8780902292  0.8039915698 0.95218889  1.00
1732   TRZ ind4b  0.8299492795  0.7504232944 0.90947526  5.00
1733   TRZ ind4b  0.8299492795  0.7504232944 0.90947526  5.00
1734   TRZ ind4b  0.8299492795  0.7504232944 0.90947526  5.00
1735   TRZ ind4b  0.8299492795  0.7504232944 0.90947526  5.00
1736   TRZ ind4b  0.7497718464  0.5792666402 0.92027705 10.00
1737   TRZ ind4b  0.7497718464  0.5792666402 0.92027705 10.00
1738   TRZ ind4b  0.7497718464  0.5792666402 0.92027705 10.00
1739   TRZ ind4b  0.7497718464  0.5792666402 0.92027705 10.00
1740   TRZ ind5a  0.8794226394  0.8218456968 0.93699958  0.01
1741   TRZ ind5a  0.8794226394  0.8218456968 0.93699958  0.01
1742   TRZ ind5a  0.8794226394  0.8218456968 0.93699958  0.01
1743   TRZ ind5a  0.8794226394  0.8218456968 0.93699958  0.01
1744   TRZ ind5a  0.8795754047  0.8223416372 0.93680917  0.05
1745   TRZ ind5a  0.8795754047  0.8223416372 0.93680917  0.05
1746   TRZ ind5a  0.8795754047  0.8223416372 0.93680917  0.05
1747   TRZ ind5a  0.8795754047  0.8223416372 0.93680917  0.05
1748   TRZ ind5a  0.8797662974  0.8229546037 0.93657799  0.10
1749   TRZ ind5a  0.8797662974  0.8229546037 0.93657799  0.10
1750   TRZ ind5a  0.8797662974  0.8229546037 0.93657799  0.10
1751   TRZ ind5a  0.8797662974  0.8229546037 0.93657799  0.10
1752   TRZ ind5a  0.8812908007  0.8275610908 0.93502051  0.50
1753   TRZ ind5a  0.8812908007  0.8275610908 0.93502051  0.50
1754   TRZ ind5a  0.8812908007  0.8275610908 0.93502051  0.50
1755   TRZ ind5a  0.8812908007  0.8275610908 0.93502051  0.50
1756   TRZ ind5a  0.8831894347  0.8324873427 0.93389153  1.00
1757   TRZ ind5a  0.8831894347  0.8324873427 0.93389153  1.00
1758   TRZ ind5a  0.8831894347  0.8324873427 0.93389153  1.00
1759   TRZ ind5a  0.8831894347  0.8324873427 0.93389153  1.00
1760   TRZ ind5a  0.8980201904  0.8362099812 0.95983040  5.00
1761   TRZ ind5a  0.8980201904  0.8362099812 0.95983040  5.00
1762   TRZ ind5a  0.8980201904  0.8362099812 0.95983040  5.00
1763   TRZ ind5a  0.8980201904  0.8362099812 0.95983040  5.00
1764   TRZ ind5a  0.9153285719  0.8144726902 1.01618445 10.00
1765   TRZ ind5a  0.9153285719  0.8144726902 1.01618445 10.00
1766   TRZ ind5a  0.9153285719  0.8144726902 1.01618445 10.00
1767   TRZ ind5a  0.9153285719  0.8144726902 1.01618445 10.00
1768   TRZ ind5b  0.9129833601  0.7206043492 1.10536237  0.01
1769   TRZ ind5b  0.9129833601  0.7206043492 1.10536237  0.01
1770   TRZ ind5b  0.9129833601  0.7206043492 1.10536237  0.01
1771   TRZ ind5b  0.9129833601  0.7206043492 1.10536237  0.01
1772   TRZ ind5b  0.9170585573  0.7215594421 1.11255767  0.05
1773   TRZ ind5b  0.9170585573  0.7215594421 1.11255767  0.05
1774   TRZ ind5b  0.9170585573  0.7215594421 1.11255767  0.05
1775   TRZ ind5b  0.9170585573  0.7215594421 1.11255767  0.05
1776   TRZ ind5b  0.9225569104  0.7256789590 1.11943486  0.10
1777   TRZ ind5b  0.9225569104  0.7256789590 1.11943486  0.10
1778   TRZ ind5b  0.9225569104  0.7256789590 1.11943486  0.10
1779   TRZ ind5b  0.9225569104  0.7256789590 1.11943486  0.10
1780   TRZ ind5b  0.9697361820  0.7993005320 1.14017183  0.50
1781   TRZ ind5b  0.9697361820  0.7993005320 1.14017183  0.50
1782   TRZ ind5b  0.9697361820  0.7993005320 1.14017183  0.50
1783   TRZ ind5b  0.9953829726  0.8673162448 1.12344970  1.00
1784   TRZ ind5b  0.9953829726  0.8673162448 1.12344970  1.00
1785   TRZ ind5b  0.9953829726  0.8673162448 1.12344970  1.00
1786   TRZ ind5b  0.9953829726  0.8673162448 1.12344970  1.00
1787   TRZ ind5b  0.9999999998  0.9999999591 1.00000004  5.00
1788   TRZ ind5b  0.9999999998  0.9999999591 1.00000004  5.00
1789   TRZ ind5b  0.9999999998  0.9999999591 1.00000004  5.00
1790   TRZ ind5b  1.0000000000  1.0000000000 1.00000000 10.00
1791   TRZ ind5b  1.0000000000  1.0000000000 1.00000000 10.00
1792   TRZ ind5b  1.0000000000  1.0000000000 1.00000000 10.00
1793   TRZ ind6a  0.9347704050  0.8586324122 1.01090840  0.01
1794   TRZ ind6a  0.9347704050  0.8586324122 1.01090840  0.01
1795   TRZ ind6a  0.9347704050  0.8586324122 1.01090840  0.01
1796   TRZ ind6a  0.9343351179  0.8580503068 1.01061993  0.05
1797   TRZ ind6a  0.9343351179  0.8580503068 1.01061993  0.05
1798   TRZ ind6a  0.9343351179  0.8580503068 1.01061993  0.05
1799   TRZ ind6a  0.9343351179  0.8580503068 1.01061993  0.05
1800   TRZ ind6a  0.9337870648  0.8573195775 1.01025455  0.10
1801   TRZ ind6a  0.9337870648  0.8573195775 1.01025455  0.10
1802   TRZ ind6a  0.9337870648  0.8573195775 1.01025455  0.10
1803   TRZ ind6a  0.9337870648  0.8573195775 1.01025455  0.10
1804   TRZ ind6a  0.9292409902  0.8513465312 1.00713545  0.50
1805   TRZ ind6a  0.9292409902  0.8513465312 1.00713545  0.50
1806   TRZ ind6a  0.9292409902  0.8513465312 1.00713545  0.50
1807   TRZ ind6a  0.9292409902  0.8513465312 1.00713545  0.50
1808   TRZ ind6a  0.9231349016  0.8435444951 1.00272531  1.00
1809   TRZ ind6a  0.9231349016  0.8435444951 1.00272531  1.00
1810   TRZ ind6a  0.9231349016  0.8435444951 1.00272531  1.00
1811   TRZ ind6a  0.9231349016  0.8435444951 1.00272531  1.00
1812   TRZ ind6a  0.8527633568  0.7614021508 0.94412456  5.00
1813   TRZ ind6a  0.8527633568  0.7614021508 0.94412456  5.00
1814   TRZ ind6a  0.8527633568  0.7614021508 0.94412456  5.00
1815   TRZ ind6a  0.8527633568  0.7614021508 0.94412456  5.00
1816   TRZ ind6a  0.6843515225  0.5057638960 0.86293915 10.00
1817   TRZ ind6a  0.6843515225  0.5057638960 0.86293915 10.00
1818   TRZ ind6a  0.6843515225  0.5057638960 0.86293915 10.00
1819   TRZ ind6a  0.6843515225  0.5057638960 0.86293915 10.00
1820   TRZ ind6b  0.9431239191  0.7754986966 1.11074914  0.01
1821   TRZ ind6b  0.9431239191  0.7754986966 1.11074914  0.01
1822   TRZ ind6b  0.9431239191  0.7754986966 1.11074914  0.01
1823   TRZ ind6b  0.9431239191  0.7754986966 1.11074914  0.01
1824   TRZ ind6b  0.9432005495  0.7771808107 1.10922029  0.05
1825   TRZ ind6b  0.9432005495  0.7771808107 1.10922029  0.05
1826   TRZ ind6b  0.9432005495  0.7771808107 1.10922029  0.05
1827   TRZ ind6b  0.9432005495  0.7771808107 1.10922029  0.05
1828   TRZ ind6b  0.9432964176  0.7792487640 1.10734407  0.10
1829   TRZ ind6b  0.9432964176  0.7792487640 1.10734407  0.10
1830   TRZ ind6b  0.9432964176  0.7792487640 1.10734407  0.10
1831   TRZ ind6b  0.9432964176  0.7792487640 1.10734407  0.10
1832   TRZ ind6b  0.9440664755  0.7942815931 1.09385136  0.50
1833   TRZ ind6b  0.9440664755  0.7942815931 1.09385136  0.50
1834   TRZ ind6b  0.9440664755  0.7942815931 1.09385136  0.50
1835   TRZ ind6b  0.9440664755  0.7942815931 1.09385136  0.50
1836   TRZ ind6b  0.9450363830  0.8086748227 1.08139794  1.00
1837   TRZ ind6b  0.9450363830  0.8086748227 1.08139794  1.00
1838   TRZ ind6b  0.9450363830  0.8086748227 1.08139794  1.00
1839   TRZ ind6b  0.9450363830  0.8086748227 1.08139794  1.00
1840   TRZ ind6b  0.9529897370  0.7480279319 1.15795154  5.00
1841   TRZ ind6b  0.9529897370  0.7480279319 1.15795154  5.00
1842   TRZ ind6b  0.9529897370  0.7480279319 1.15795154  5.00
1843   TRZ ind6b  0.9529897370  0.7480279319 1.15795154  5.00
1844   TRZ ind6b  0.9629014045  0.5988039129 1.32699890 10.00
1845   TRZ ind6b  0.9629014045  0.5988039129 1.32699890 10.00
1846   TRZ ind6b  0.9629014045  0.5988039129 1.32699890 10.00
1847   TRZ ind6b  0.9629014045  0.5988039129 1.32699890 10.00
1848   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.01
1849   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.01
1850   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.01
1851   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.01
1852   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.05
1853   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.05
1854   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.05
1855   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.05
1856   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.10
1857   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.10
1858   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.10
1859   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.10
1860   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.50
1861   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.50
1862   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.50
1863   VEH ind1a  0.9960578161  0.9136774476 1.07843818  0.50
1864   VEH ind1a  0.9960578161  0.9136774476 1.07843818  1.00
1865   VEH ind1a  0.9960578161  0.9136774476 1.07843818  1.00
1866   VEH ind1a  0.9960578161  0.9136774476 1.07843818  1.00
1867   VEH ind1a  0.9960578161  0.9136774476 1.07843818  1.00
1868   VEH ind1a  0.9960578161  0.9136774476 1.07843818  5.00
1869   VEH ind1a  0.9960578161  0.9136774476 1.07843818  5.00
1870   VEH ind1a  0.9960578161  0.9136774476 1.07843818  5.00
1871   VEH ind1a  0.9960578161  0.9136774476 1.07843818  5.00
1872   VEH ind1a  0.9960578161  0.9136774476 1.07843818 10.00
1873   VEH ind1a  0.9960578161  0.9136774476 1.07843818 10.00
1874   VEH ind1a  0.9960578161  0.9136774476 1.07843818 10.00
1875   VEH ind1a  0.9960578161  0.9136774476 1.07843818 10.00
1876   VEH ind1a  0.9960578161  0.9136774476 1.07843818 50.00
1877   VEH ind1a  0.9960578161  0.9136774476 1.07843818 50.00
1878   VEH ind1a  0.9960578161  0.9136774476 1.07843818 50.00
1879   VEH ind1a  0.9960578161  0.9136774476 1.07843818 50.00
1880   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.01
1881   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.01
1882   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.01
1883   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.01
1884   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.05
1885   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.05
1886   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.05
1887   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.05
1888   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.10
1889   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.10
1890   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.50
1891   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.50
1892   VEH ind1b  1.0160693942  0.9410006835 1.09113810  0.50
1893   VEH ind1b  1.0160693942  0.9410006835 1.09113810  1.00
1894   VEH ind1b  1.0160693942  0.9410006835 1.09113810  1.00
1895   VEH ind1b  1.0160693942  0.9410006835 1.09113810  1.00
1896   VEH ind1b  1.0160693942  0.9410006835 1.09113810  5.00
1897   VEH ind1b  1.0160693942  0.9410006835 1.09113810  5.00
1898   VEH ind1b  1.0160693942  0.9410006835 1.09113810  5.00
1899   VEH ind1b  1.0160693942  0.9410006835 1.09113810  5.00
1900   VEH ind1b  1.0160693942  0.9410006835 1.09113810 10.00
1901   VEH ind1b  1.0160693942  0.9410006835 1.09113810 10.00
1902   VEH ind1b  1.0160693942  0.9410006835 1.09113810 10.00
1903   VEH ind1b  1.0160693942  0.9410006835 1.09113810 50.00
1904   VEH ind1b  1.0160693942  0.9410006835 1.09113810 50.00
1905   VEH ind1b  1.0160693942  0.9410006835 1.09113810 50.00
1906   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.01
1907   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.01
1908   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.01
1909   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.01
1910   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.05
1911   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.05
1912   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.05
1913   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.05
1914   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.10
1915   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.10
1916   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.10
1917   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.10
1918   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.50
1919   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.50
1920   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.50
1921   VEH ind2a  0.9714657432  0.9480167236 0.99491476  0.50
1922   VEH ind2a  0.9714657432  0.9480167236 0.99491476  1.00
1923   VEH ind2a  0.9714657432  0.9480167236 0.99491476  1.00
1924   VEH ind2a  0.9714657432  0.9480167236 0.99491476  1.00
1925   VEH ind2a  0.9714657432  0.9480167236 0.99491476  1.00
1926   VEH ind2a  0.9714657432  0.9480167236 0.99491476  5.00
1927   VEH ind2a  0.9714657432  0.9480167236 0.99491476  5.00
1928   VEH ind2a  0.9714657432  0.9480167236 0.99491476  5.00
1929   VEH ind2a  0.9714657432  0.9480167236 0.99491476  5.00
1930   VEH ind2a  0.9714657432  0.9480167236 0.99491476 10.00
1931   VEH ind2a  0.9714657432  0.9480167236 0.99491476 10.00
1932   VEH ind2a  0.9714657432  0.9480167236 0.99491476 10.00
1933   VEH ind2a  0.9714657432  0.9480167236 0.99491476 10.00
1934   VEH ind2a  0.9714657432  0.9480167236 0.99491476 50.00
1935   VEH ind2a  0.9714657432  0.9480167236 0.99491476 50.00
1936   VEH ind2a  0.9714657432  0.9480167236 0.99491476 50.00
1937   VEH ind2a  0.9714657432  0.9480167236 0.99491476 50.00
1938   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.01
1939   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.01
1940   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.01
1941   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.01
1942   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.05
1943   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.05
1944   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.05
1945   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.05
1946   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.10
1947   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.10
1948   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.10
1949   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.10
1950   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.50
1951   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.50
1952   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.50
1953   VEH ind2b  1.0871616282  1.0234336284 1.15088963  0.50
1954   VEH ind2b  1.0871616282  1.0234336284 1.15088963  1.00
1955   VEH ind2b  1.0871616282  1.0234336284 1.15088963  1.00
1956   VEH ind2b  1.0871616282  1.0234336284 1.15088963  1.00
1957   VEH ind2b  1.0871616282  1.0234336284 1.15088963  1.00
1958   VEH ind2b  1.0871616282  1.0234336284 1.15088963  5.00
1959   VEH ind2b  1.0871616282  1.0234336284 1.15088963  5.00
1960   VEH ind2b  1.0871616282  1.0234336284 1.15088963  5.00
1961   VEH ind2b  1.0871616282  1.0234336284 1.15088963  5.00
1962   VEH ind2b  1.0871616282  1.0234336284 1.15088963 10.00
1963   VEH ind2b  1.0871616282  1.0234336284 1.15088963 10.00
1964   VEH ind2b  1.0871616282  1.0234336284 1.15088963 10.00
1965   VEH ind2b  1.0871616282  1.0234336284 1.15088963 10.00
1966   VEH ind2b  1.0871616282  1.0234336284 1.15088963 50.00
1967   VEH ind2b  1.0871616282  1.0234336284 1.15088963 50.00
1968   VEH ind2b  1.0871616282  1.0234336284 1.15088963 50.00
1969   VEH ind2b  1.0871616282  1.0234336284 1.15088963 50.00
1970   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.01
1971   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.01
1972   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.01
1973   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.01
1974   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.05
1975   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.05
1976   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.05
1977   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.05
1978   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.10
1979   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.10
1980   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.10
1981   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.10
1982   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.50
1983   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.50
1984   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.50
1985   VEH ind3a  1.1012547918  0.9625342956 1.23997529  0.50
1986   VEH ind3a  1.1012547918  0.9625342956 1.23997529  1.00
1987   VEH ind3a  1.1012547918  0.9625342956 1.23997529  1.00
1988   VEH ind3a  1.1012547918  0.9625342956 1.23997529  1.00
1989   VEH ind3a  1.1012547918  0.9625342956 1.23997529  1.00
1990   VEH ind3a  1.1012547918  0.9625342956 1.23997529  5.00
1991   VEH ind3a  1.1012547918  0.9625342956 1.23997529  5.00
1992   VEH ind3a  1.1012547918  0.9625342956 1.23997529  5.00
1993   VEH ind3a  1.1012547918  0.9625342956 1.23997529  5.00
1994   VEH ind3a  1.1012547918  0.9625342956 1.23997529 10.00
1995   VEH ind3a  1.1012547918  0.9625342956 1.23997529 10.00
1996   VEH ind3a  1.1012547918  0.9625342956 1.23997529 10.00
1997   VEH ind3a  1.1012547918  0.9625342956 1.23997529 10.00
1998   VEH ind3a  1.1012547918  0.9625342956 1.23997529 50.00
1999   VEH ind3a  1.1012547918  0.9625342956 1.23997529 50.00
2000   VEH ind3a  1.1012547918  0.9625342956 1.23997529 50.00
2001   VEH ind3a  1.1012547918  0.9625342956 1.23997529 50.00
2002   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.01
2003   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.01
2004   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.01
2005   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.01
2006   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.05
2007   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.05
2008   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.05
2009   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.05
2010   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.10
2011   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.10
2012   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.10
2013   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.10
2014   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.50
2015   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.50
2016   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.50
2017   VEH ind3b  1.0142815635  0.9187698912 1.10979324  0.50
2018   VEH ind3b  1.0142815635  0.9187698912 1.10979324  1.00
2019   VEH ind3b  1.0142815635  0.9187698912 1.10979324  1.00
2020   VEH ind3b  1.0142815635  0.9187698912 1.10979324  1.00
2021   VEH ind3b  1.0142815635  0.9187698912 1.10979324  5.00
2022   VEH ind3b  1.0142815635  0.9187698912 1.10979324  5.00
2023   VEH ind3b  1.0142815635  0.9187698912 1.10979324  5.00
2024   VEH ind3b  1.0142815635  0.9187698912 1.10979324  5.00
2025   VEH ind3b  1.0142815635  0.9187698912 1.10979324 10.00
2026   VEH ind3b  1.0142815635  0.9187698912 1.10979324 10.00
2027   VEH ind3b  1.0142815635  0.9187698912 1.10979324 10.00
2028   VEH ind3b  1.0142815635  0.9187698912 1.10979324 10.00
2029   VEH ind3b  1.0142815635  0.9187698912 1.10979324 50.00
2030   VEH ind3b  1.0142815635  0.9187698912 1.10979324 50.00
2031   VEH ind3b  1.0142815635  0.9187698912 1.10979324 50.00
2032   VEH ind3b  1.0142815635  0.9187698912 1.10979324 50.00
2033   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.01
2034   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.01
2035   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.01
2036   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.01
2037   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.05
2038   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.05
2039   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.05
2040   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.05
2041   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.10
2042   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.10
2043   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.10
2044   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.10
2045   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.50
2046   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.50
2047   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.50
2048   VEH ind4a  1.0319922286  0.9686535152 1.09533094  0.50
2049   VEH ind4a  1.0319922286  0.9686535152 1.09533094  1.00
2050   VEH ind4a  1.0319922286  0.9686535152 1.09533094  1.00
2051   VEH ind4a  1.0319922286  0.9686535152 1.09533094  1.00
2052   VEH ind4a  1.0319922286  0.9686535152 1.09533094  1.00
2053   VEH ind4a  1.0319922286  0.9686535152 1.09533094  5.00
2054   VEH ind4a  1.0319922286  0.9686535152 1.09533094  5.00
2055   VEH ind4a  1.0319922286  0.9686535152 1.09533094  5.00
2056   VEH ind4a  1.0319922286  0.9686535152 1.09533094  5.00
2057   VEH ind4a  1.0319922286  0.9686535152 1.09533094 10.00
2058   VEH ind4a  1.0319922286  0.9686535152 1.09533094 10.00
2059   VEH ind4a  1.0319922286  0.9686535152 1.09533094 10.00
2060   VEH ind4a  1.0319922286  0.9686535152 1.09533094 50.00
2061   VEH ind4a  1.0319922286  0.9686535152 1.09533094 50.00
2062   VEH ind4a  1.0319922286  0.9686535152 1.09533094 50.00
2063   VEH ind4a  1.0319922286  0.9686535152 1.09533094 50.00
2064   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.01
2065   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.01
2066   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.01
2067   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.01
2068   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.05
2069   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.05
2070   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.05
2071   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.05
2072   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.10
2073   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.10
2074   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.10
2075   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.50
2076   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.50
2077   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.50
2078   VEH ind4b  0.9737443458  0.9233437728 1.02414492  0.50
2079   VEH ind4b  0.9737443458  0.9233437728 1.02414492  1.00
2080   VEH ind4b  0.9737443458  0.9233437728 1.02414492  1.00
2081   VEH ind4b  0.9737443458  0.9233437728 1.02414492  1.00
2082   VEH ind4b  0.9737443458  0.9233437728 1.02414492  1.00
2083   VEH ind4b  0.9737443458  0.9233437728 1.02414492  5.00
2084   VEH ind4b  0.9737443458  0.9233437728 1.02414492  5.00
2085   VEH ind4b  0.9737443458  0.9233437728 1.02414492  5.00
2086   VEH ind4b  0.9737443458  0.9233437728 1.02414492  5.00
2087   VEH ind4b  0.9737443458  0.9233437728 1.02414492 10.00
2088   VEH ind4b  0.9737443458  0.9233437728 1.02414492 10.00
2089   VEH ind4b  0.9737443458  0.9233437728 1.02414492 10.00
2090   VEH ind4b  0.9737443458  0.9233437728 1.02414492 10.00
2091   VEH ind4b  0.9737443458  0.9233437728 1.02414492 50.00
2092   VEH ind4b  0.9737443458  0.9233437728 1.02414492 50.00
2093   VEH ind4b  0.9737443458  0.9233437728 1.02414492 50.00
2094   VEH ind4b  0.9737443458  0.9233437728 1.02414492 50.00
2095   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.01
2096   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.01
2097   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.01
2098   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.01
2099   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.05
2100   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.05
2101   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.05
2102   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.05
2103   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.10
2104   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.10
2105   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.10
2106   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.10
2107   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.50
2108   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.50
2109   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.50
2110   VEH ind5a  0.9665757283  0.9071614034 1.02599005  0.50
2111   VEH ind5a  0.9665757283  0.9071614034 1.02599005  1.00
2112   VEH ind5a  0.9665757283  0.9071614034 1.02599005  1.00
2113   VEH ind5a  0.9665757283  0.9071614034 1.02599005  1.00
2114   VEH ind5a  0.9665757283  0.9071614034 1.02599005  1.00
2115   VEH ind5a  0.9665757283  0.9071614034 1.02599005  5.00
2116   VEH ind5a  0.9665757283  0.9071614034 1.02599005  5.00
2117   VEH ind5a  0.9665757283  0.9071614034 1.02599005  5.00
2118   VEH ind5a  0.9665757283  0.9071614034 1.02599005  5.00
2119   VEH ind5a  0.9665757283  0.9071614034 1.02599005 10.00
2120   VEH ind5a  0.9665757283  0.9071614034 1.02599005 10.00
2121   VEH ind5a  0.9665757283  0.9071614034 1.02599005 10.00
2122   VEH ind5a  0.9665757283  0.9071614034 1.02599005 10.00
2123   VEH ind5a  0.9665757283  0.9071614034 1.02599005 50.00
2124   VEH ind5a  0.9665757283  0.9071614034 1.02599005 50.00
2125   VEH ind5a  0.9665757283  0.9071614034 1.02599005 50.00
2126   VEH ind5a  0.9665757283  0.9071614034 1.02599005 50.00
2127   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.01
2128   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.01
2129   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.01
2130   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.01
2131   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.05
2132   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.05
2133   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.05
2134   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.05
2135   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.10
2136   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.10
2137   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.10
2138   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.10
2139   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.50
2140   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.50
2141   VEH ind5b  1.0634908025  0.9782724070 1.14870920  0.50
2142   VEH ind5b  1.0634908025  0.9782724070 1.14870920  1.00
2143   VEH ind5b  1.0634908025  0.9782724070 1.14870920  1.00
2144   VEH ind5b  1.0634908025  0.9782724070 1.14870920  1.00
2145   VEH ind5b  1.0634908025  0.9782724070 1.14870920  1.00
2146   VEH ind5b  1.0634908025  0.9782724070 1.14870920  5.00
2147   VEH ind5b  1.0634908025  0.9782724070 1.14870920  5.00
2148   VEH ind5b  1.0634908025  0.9782724070 1.14870920  5.00
2149   VEH ind5b  1.0634908025  0.9782724070 1.14870920  5.00
2150   VEH ind5b  1.0634908025  0.9782724070 1.14870920 10.00
2151   VEH ind5b  1.0634908025  0.9782724070 1.14870920 10.00
2152   VEH ind5b  1.0634908025  0.9782724070 1.14870920 10.00
2153   VEH ind5b  1.0634908025  0.9782724070 1.14870920 10.00
2154   VEH ind5b  1.0634908025  0.9782724070 1.14870920 50.00
2155   VEH ind5b  1.0634908025  0.9782724070 1.14870920 50.00
2156   VEH ind5b  1.0634908025  0.9782724070 1.14870920 50.00
2157   VEH ind5b  1.0634908025  0.9782724070 1.14870920 50.00
2158   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.01
2159   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.01
2160   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.01
2161   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.01
2162   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.05
2163   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.05
2164   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.05
2165   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.05
2166   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.10
2167   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.10
2168   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.10
2169   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.10
2170   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.50
2171   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.50
2172   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.50
2173   VEH ind6a  1.0378499887  0.9726571531 1.10304282  0.50
2174   VEH ind6a  1.0378499887  0.9726571531 1.10304282  1.00
2175   VEH ind6a  1.0378499887  0.9726571531 1.10304282  1.00
2176   VEH ind6a  1.0378499887  0.9726571531 1.10304282  1.00
2177   VEH ind6a  1.0378499887  0.9726571531 1.10304282  5.00
2178   VEH ind6a  1.0378499887  0.9726571531 1.10304282  5.00
2179   VEH ind6a  1.0378499887  0.9726571531 1.10304282  5.00
2180   VEH ind6a  1.0378499887  0.9726571531 1.10304282  5.00
2181   VEH ind6a  1.0378499887  0.9726571531 1.10304282 10.00
2182   VEH ind6a  1.0378499887  0.9726571531 1.10304282 10.00
2183   VEH ind6a  1.0378499887  0.9726571531 1.10304282 10.00
2184   VEH ind6a  1.0378499887  0.9726571531 1.10304282 10.00
2185   VEH ind6a  1.0378499887  0.9726571531 1.10304282 50.00
2186   VEH ind6a  1.0378499887  0.9726571531 1.10304282 50.00
2187   VEH ind6a  1.0378499887  0.9726571531 1.10304282 50.00
2188   VEH ind6a  1.0378499887  0.9726571531 1.10304282 50.00
2189   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.01
2190   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.01
2191   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.01
2192   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.01
2193   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.05
2194   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.05
2195   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.05
2196   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.05
2197   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.10
2198   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.10
2199   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.10
2200   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.10
2201   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.50
2202   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.50
2203   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.50
2204   VEH ind6b  1.0182855916  0.8820622189 1.15450896  0.50
2205   VEH ind6b  1.0182855916  0.8820622189 1.15450896  1.00
2206   VEH ind6b  1.0182855916  0.8820622189 1.15450896  1.00
2207   VEH ind6b  1.0182855916  0.8820622189 1.15450896  1.00
2208   VEH ind6b  1.0182855916  0.8820622189 1.15450896  1.00
2209   VEH ind6b  1.0182855916  0.8820622189 1.15450896  5.00
2210   VEH ind6b  1.0182855916  0.8820622189 1.15450896  5.00
2211   VEH ind6b  1.0182855916  0.8820622189 1.15450896  5.00
2212   VEH ind6b  1.0182855916  0.8820622189 1.15450896  5.00
2213   VEH ind6b  1.0182855916  0.8820622189 1.15450896 10.00
2214   VEH ind6b  1.0182855916  0.8820622189 1.15450896 10.00
2215   VEH ind6b  1.0182855916  0.8820622189 1.15450896 10.00
2216   VEH ind6b  1.0182855916  0.8820622189 1.15450896 10.00
2217   VEH ind6b  1.0182855916  0.8820622189 1.15450896 50.00
2218   VEH ind6b  1.0182855916  0.8820622189 1.15450896 50.00
2219   VEH ind6b  1.0182855916  0.8820622189 1.15450896 50.00
2220   VEH ind6b  1.0182855916  0.8820622189 1.15450896 50.00
# brewer.pal(n=6,"Dark2")
# [1] "#1B9E77" "#D95F02" "#7570B3" "#E7298A" "#66A61E" "#E6AB02"
# > display.brewer.pal(n=6,"Dark2")
for (each in 1:6){
  newdata <- intervals %>% 
    separate("trt", into=c("sDrug",NA)) %>% 
    dplyr::filter(sDrug ==drug_list[each]) %>% 
    mutate(SampleID=indv) %>% 
    mutate(indv=substr(indv,4,4)) %>% 
    mutate(indv=factor(indv, levels=lvl_order)) %>% 
    dplyr::filter(SampleID %in% doubl_plot)
    
  
  # newdata <- sub_intv %>% 
  #  filter(indv %in% doubl_plot) %>% 
  #   mutate(sub_ind=substr(indv,4,4)) %>% 
  #   mutate(sub_ind=factor(sub_ind,levels=lvl_order))
  drug_plot <- DRC_list[[each]]
     f <-
       drug_plot %>% 
         filter(SampleID %in% doubl_plot) %>% 
         ggplot(., aes(x=Conc, y= Percent, group=SampleID,linetype=SampleID, color= indv,alpha =0.6 )) +
         guides(color="none", alpha = "none")+
         stat_smooth(method = "drm",
                     method.args = list(fct = L.4(c(NA,NA,1,NA))),
                     se = FALSE)+
         geom_ribbon(data = newdata, 
                     aes(x = Conc, y = Prediction, 
                         ymin = Lower, 
                         ymax = Upper, 
                         fill=indv),
                         alpha = 0.1, 
                         color = "transparent")+
         ylim(-.4,1.5)+
         scale_linetype_manual(values = c("dotted","solid","dotted","solid"),
                               name="replicate",
                               labels=c("Rep 1", "Rep 2","Rep 1", "Rep 2"))+
         scale_color_brewer(palette = "Dark2")+
         scale_fill_brewer(palette = "Dark2")+
         scale_x_log10() +  # Change the x-axis scale to log 10 scale
         theme_classic() +
         xlab(NULL)+
         ylab(NULL)+
        # scale_y_continuous(oob=scales::rescale_max, limits = -.4, 1.5)+
        ggtitle(drug_list[each])+
      theme(plot.title = element_text(hjust = 0.5, size =15, face ="bold"),
            axis.title=element_text(size=10),
            axis.ticks=element_line(linewidth = 2),
            axis.text=element_text(size=10, face = "bold"),
            panel.grid.major = element_line(colour = 'lightgrey'),
            panel.border=element_rect(fill = NA, linewidth = 2),
            plot.background = element_rect(fill = "white", colour = NA))
       
  print(f)
} 

Fig. S3

viability <- readRDS("data/viability.RDS")
norm_LDH48 <- readRDS("data/supp_normLDH48.RDS")
viability %>% 
  full_join(., norm_LDH48,by = c("indv","Drug","Conc")) %>% 
  ggplot(., aes(x=per.live, y=ldh))+
  geom_point(aes(col=indv))+
  geom_smooth(method="lm")+
  facet_wrap("Drug")+
  theme_bw()+
  xlab("Average viability of cardiomyocytes/100") +
  ylab("Average LDH") +
  ggtitle("Cell stress and viability correlation")+
  scale_color_brewer(palette = "Dark2",name = "Individual", label = c("1","2","3","4","5","6"))+
  stat_cor(method="pearson",aes(label = paste(..r.label.., ..p.label.., sep = "~`,`~")),
           color = "red")+
  theme(plot.title = element_text(size = rel(1.5), hjust = 0.5,face = "bold"),
        axis.title = element_text(size = 15, color = "black"),
        axis.ticks = element_line(size = 1.5),
        axis.text = element_text(size = 8, color = "black", angle = 20),
        strip.text.x = element_text(size = 15, color = "black", face = "bold"),
        strip.background = element_rect(fill = "white")) 

Fig. S4

viabilitytable <- readRDS("data/averageviabilitytable.RDS")
viabilitytable %>% 
  ungroup() %>% 
    mutate(indv=substr(SampleID,4,4)) %>% 
     mutate(indv=factor(indv, levels= c('1','2','3','4','5','6'))) %>% 
    filter(Conc ==0.5) %>%
    # mutate(Conc= factor(as.numeric(Conc))) %>% 
    group_by(indv,sDrug,Conc) %>% 
    dplyr::summarize(Viability=mean(Mean)) %>%
    ungroup() %>% 
    ggplot(.,  aes(x=sDrug, y= Viability*100 )) +
    geom_boxplot(position="dodge", outlier.colour = "transparent",
                 aes(fill=sDrug))+
    geom_point(aes(color=indv))+
    guides(alpha = "none")+
    ylim(0,150.5)+
    scale_color_brewer(palette = "Dark2",
                       guide="legend",
                       name ="Individual", 
                       labels(c(1,2,3,4,5,6)))+
    scale_fill_manual(values=drug_pal_fact, name ="Treatment")+
    theme_classic() +
  xlab("")+
    # geom_hline(yintercept = 1,lty = 4)+
    ylab("% Viability") +
    facet_wrap(~Conc)+ 
    ggtitle(expression(paste("Viablity across treatment at 0.5", mu, "M at 48 hours")))+
    theme(axis.title=element_text(size=10),
          axis.ticks=element_line(size =2),
          axis.text.y=element_text(size=9, face = "bold"),
          axis.text.x=element_blank(),
          panel.grid.major = element_line(colour = 'darkgrey'),
          panel.border=element_rect(fill = NA, size = 2),
          plot.title = element_text(hjust = 0.5, size =15, face = "bold"))

viabilitytable %>% 
  ungroup() %>% 
    mutate(indv=substr(SampleID,4,4)) %>% 
     mutate(indv=factor(indv, levels= c('1','2','3','4','5','6'))) %>% 
    filter(Conc <5) %>%
    mutate(Conc= factor(as.numeric(Conc))) %>%
    group_by(indv,sDrug,Conc) %>% 
    dplyr::summarize(Viability=mean(Mean)) %>%
    ungroup() %>% 
    ggplot(.,  aes(x=sDrug, y= Viability*100 )) +
    geom_boxplot(position="dodge", outlier.colour = "transparent",
                 aes(fill=sDrug))+
    geom_point(aes(color=indv))+
    guides(alpha = "none")+
    ylim(0,150.5)+
    scale_color_brewer(palette = "Dark2",
                       guide="legend",
                       name ="individual", 
                       labels(c(1,2,3,4,5,6)))+
    scale_fill_manual(values=drug_pal_fact, name ="treatment")+
    theme_classic() +
  xlab("")+
    # geom_hline(yintercept = 1,lty = 4)+
    ylab("% Viability") +
    facet_wrap(~Conc)+ 
    # ggtitle(expression(paste("Viablity across treatment at 0.5", mu, "M at 48 hours")))+
    theme(axis.title=element_text(size=10),
          axis.ticks=element_line(size =2),
          axis.text.y=element_text(size=9, face = "bold"),
          axis.text.x=element_blank(),
          panel.grid.major = element_line(colour = 'darkgrey'),
          panel.border=element_rect(fill = NA, size = 2),
          plot.title = element_text(hjust = 0.5, size =15, face = "bold"))

Fig. S5

library(limma)
library(edgeR)
library(cowplot)
filcpm_matrix <- readRDS("data/filcpm_counts.RDS")
colnames(filcpm_matrix)
 [1] "Da.1.3h"  "Do.1.3h"  "Ep.1.3h"  "Mi.1.3h"  "Tr.1.3h"  "Ve.1.3h" 
 [7] "Da.1.24h" "Do.1.24h" "Ep.1.24h" "Mi.1.24h" "Tr.1.24h" "Ve.1.24h"
[13] "Da.2.3h"  "Do.2.3h"  "Ep.2.3h"  "Mi.2.3h"  "Tr.2.3h"  "Ve.2.3h" 
[19] "Da.2.24h" "Do.2.24h" "Ep.2.24h" "Mi.2.24h" "Tr.2.24h" "Ve.2.24h"
[25] "Da.3.3h"  "Do.3.3h"  "Ep.3.3h"  "Mi.3.3h"  "Tr.3.3h"  "Ve.3.3h" 
[31] "Da.3.24h" "Do.3.24h" "Ep.3.24h" "Mi.3.24h" "Tr.3.24h" "Ve.3.24h"
[37] "Da.4.3h"  "Do.4.3h"  "Ep.4.3h"  "Mi.4.3h"  "Tr.4.3h"  "Ve.4.3h" 
[43] "Da.4.24h" "Do.4.24h" "Ep.4.24h" "Mi.4.24h" "Tr.4.24h" "Ve.4.24h"
[49] "Da.5.3h"  "Do.5.3h"  "Ep.5.3h"  "Mi.5.3h"  "Tr.5.3h"  "Ve.5.3h" 
[55] "Da.5.24h" "Do.5.24h" "Ep.5.24h" "Mi.5.24h" "Tr.5.24h" "Ve.5.24h"
[61] "Da.6.3h"  "Do.6.3h"  "Ep.6.3h"  "Mi.6.3h"  "Tr.6.3h"  "Ve.6.3h" 
[67] "Da.6.24h" "Do.6.24h" "Ep.6.24h" "Mi.6.24h" "Tr.6.24h" "Ve.6.24h"
x <- readRDS("data/filtermatrix_x.RDS")
x$samples %>% 
  mutate(drug=case_match(drug, "Daunorubicin"~"DNR",
                        "Doxorubicin"~"DOX",
                        "Epirubicin"~"EPI",
                        "Mitoxantrone"~"MTX",
                        "Trastuzumab"~"TRZ",
                        "Vehicle"~"VEH", .default = drug)) %>%
   mutate(drug=factor(drug, levels = c('DOX','EPI','DNR','MTX','TRZ','VEH'))) %>% 
  mutate(time=factor(time, labels= c("3 hours","24 hours"))) %>% 
 ggplot(., aes(x = as.factor(time), y = RIN)) +
  geom_boxplot(aes(fill=as.factor(time)))+ 
  theme_bw()+
  ylim(c(0,10))+
  labs(x= "", fill ="Time in hours",y ="RNA Integrity Number")+ 
  ggtitle("Boxplot of RIN by time and drug")+
  facet_wrap(~drug)+
  theme(plot.title = element_text(size = rel(1.5), hjust = 0.5),
        axis.title = element_text(size = 15, color = "black"),
        axis.text.y = element_text(size =10, color = "black", angle = 0, hjust = 0.8, vjust = 0.5),
        axis.text.x = element_text(size =10, color = "black", angle = 0, hjust = 1, vjust = 0.2),
        strip.text.x = element_text(size = 15, color = "black", face = "bold"),
        strip.background = element_rect(fill = "white"))

seq_info <-read.csv("output/sequencing_info.txt", row.names = 1)
seq_info %>% 
   
  filter(type=="Total_reads") %>% 
  mutate(drug=case_match(drug, "Daunorubicin"~"DNR",
                        "Doxorubicin"~"DOX",
                        "Epirubicin"~"EPI",
                        "Mitoxantrone"~"MTX",
                        "Trastuzumab"~"TRZ",
                        "Vehicle"~"VEH", .default = drug)) %>%
   mutate(drug=factor(drug, levels = c('DOX','EPI','DNR','MTX','TRZ','VEH'))) %>% 
    ggplot(., aes (x =drug, y=Total.Sequences, fill = drug))+
  geom_boxplot()+
  scale_fill_manual(values=drug_pal_fact)+
  ggtitle(expression("Total number of reads by treatment"))+
  xlab(" ")+
  ylab(expression("RNA -sequencing reads"))+
  theme_bw()+
  theme(plot.title = element_text(size = rel(1.5), hjust = 0.5),
        axis.title = element_text(size = 12, color = "black"),
        axis.ticks = element_line(linewidth = 1.5),
        axis.line = element_line(linewidth = 1.5),
        axis.text.y = element_text(size =10, color = "black", angle = 0, hjust = 0.8, vjust = 0.5),
        axis.text.x = element_text(size =10, color = "white"),
        #strip.text.x = element_text(size = 15, color = "black", face = "bold"),
        strip.text.y = element_text(color = "white"))

seq_info %>% 
  mutate(drug=case_match(drug, "Daunorubicin"~"DNR",
                        "Doxorubicin"~"DOX",
                        "Epirubicin"~"EPI",
                        "Mitoxantrone"~"MTX",
                        "Trastuzumab"~"TRZ",
                        "Vehicle"~"VEH", .default = drug)) %>%
   mutate(drug=factor(drug, levels = c('DOX','EPI','DNR','MTX','TRZ','VEH'))) %>% 
  # separate(samplenames, into=c(NA,NA,NA,"samplenames")) %>% 
  # mutate(shortnames = paste("Sample",str_trim(samplenames))) %>% 
  filter(type=="Total_reads") %>% 
  mutate(sampleID=colnames(filcpm_matrix)) %>% 
  ggplot(., aes (x =sampleID, y=Total.Sequences, fill = drug, group_by=indv))+
  geom_col()+
 geom_hline(aes(yintercept=20000000))+
 scale_fill_manual(values=drug_pal_fact)+
  ggtitle(expression("Total number of reads by sample"))+
  xlab("")+
  ylab(expression("RNA -sequencing reads"))+
  theme_bw()+
  theme(plot.title = element_text(size = rel(2), hjust = 0.5),
        axis.title = element_text(size = 15, color = "black"),
        axis.ticks = element_line(linewidth = 1.5),
        axis.line = element_line(linewidth = 1.5),
        axis.text.y = element_text(size =10, color = "black", angle = 0, hjust = 0.8, vjust = 0.5),
        axis.text.x = element_text(size =6, color = "black", angle = 90, hjust = 1, vjust = 0.2),
        #strip.text.x = element_text(size = 15, color = "black", face = "bold"),
        strip.text.y = element_text(color = "white"))

### Fig. S6

filcpm_matrix <- readRDS("data/filcpm_counts.RDS")

mcor <- cor(filcpm_matrix) 

filmat_groupmat_col <- data.frame(timeset = colnames(filcpm_matrix))
counts_corr_mat<- filmat_groupmat_col %>% 
  separate(timeset, into= c("drug","indv","time")) %>% 
  mutate(class = if_else(drug=="Da","AC", if_else(drug=="Do","AC", if_else(drug=="Ep","AC","nAC")))) %>% 
  mutate(TOP2i = if_else(drug=="Da","yes", if_else(drug=="Do","yes", if_else(drug=="Ep","yes",if_else(drug=="Mi","yes","no"))))) 
                         
 mat_colors <- list( 
   drug= c("#F1B72B","#8B006D","#DF707E","#3386DD","#707031","#41B333"),
   indv=c("#1B9E77", "#D95F02" ,"#7570B3", "#E7298A" ,"#66A61E", "#E6AB02"),
   time=c("pink", "chocolate4"),
   class=c("yellow1","lightgreen"), 
   TOP2i =c("darkgreen","goldenrod"))                        
                         
names(mat_colors$drug)   <- unique(counts_corr_mat$drug)                      
names(mat_colors$indv) <- unique(counts_corr_mat$indv)
names(mat_colors$time) <- unique(counts_corr_mat$time)
names(mat_colors$class) <- unique(counts_corr_mat$class)
names(mat_colors$TOP2i) <- unique(counts_corr_mat$TOP2i)


ComplexHeatmap::pheatmap(mcor,
                         # column_title=(paste0("RNA-seq log"[2]~"cpm correlation")),
        annotation_col = counts_corr_mat,
        annotation_colors = mat_colors,
                         fontsize=10,
                         fontsize_row = 8,
                         angle_col="90",
                         treeheight_row=25,
                         fontsize_col = 8,
                         treeheight_col = 20)

heatmap is pending a few changes! just not my focus today.

Fig. S7

pca_all_anno <- readRDS("data/supp_pca_all_anno.RDS")
pca_all_anno <- pca_all_anno %>% 
  mutate(drug = case_match(drug, "Daunorubicin"~"DNR","Doxorubicin"~"DOX", "Epirubicin"~"EPI","Mitoxantrone"~"MTX","Trastuzumab"~"TRX","Vehicle"~"VEH", .default = drug))


facs <- c("indv", "drug", "time")
names(facs) <- c("Individual", "Treatment", "Time")

get_regr_pval <- function(mod) {
  # Returns the p-value for the Fstatistic of a linear model
  # mod: class lm
  stopifnot(class(mod) == "lm")
  fstat <- summary(mod)$fstatistic
  pval <- 1 - pf(fstat[1], fstat[2], fstat[3])
  return(pval)
}

plot_versus_pc <- function(df, pc_num, fac) {
  # df: data.frame
  # pc_num: numeric, specific PC for plotting
  # fac: column name of df for plotting against PC
  pc_char <- paste0("PC", pc_num)
  # Calculate F-statistic p-value for linear model
  pval <- get_regr_pval(lm(df[, pc_char] ~ df[, fac]))
  if (is.numeric(df[, f])) {
    ggplot(df, aes_string(x = f, y = pc_char)) + geom_point() +
      geom_smooth(method = "lm") + labs(title = sprintf("p-val: %.2f", pval))
  } else {
    ggplot(df, aes_string(x = f, y = pc_char)) + geom_boxplot() +
      labs(title = sprintf("p-val: %.2f", pval))
  }
}

for (f in facs) {
    # Plot f versus PC1 and PC2
  f_v_pc1 <- arrangeGrob(plot_versus_pc(pca_all_anno, 1, f)+theme_bw())
  f_v_pc2 <- arrangeGrob(plot_versus_pc(pca_all_anno, 2, f)+theme_bw())
  grid.arrange(f_v_pc1, f_v_pc2, ncol = 2, top = names(facs)[which(facs == f)])
}

Fig. S8

Volcanoplots <- readRDS("output/Volcanoplot_10.RDS")
Volcanoplots

Fig. S9

toplistall <- readRDS("data/toplistall.RDS")
toplistall %>% 
  group_by(time, id) %>% 
  mutate(id=factor(id, levels = c('DOX', 'EPI', 'DNR', 'MTX', 'TRZ','VEH'))) %>% 
  mutate(time= factor(time,
     levels=c("3_hours","24_hours"),
              label=c("3 hours","24 hours"))) %>%
  ggplot(., aes(x=id, y=logFC))+
  geom_boxplot(aes(fill=id))+
  ggpubr::fill_palette(palette =drug_pal_fact)+
  guides(fill=guide_legend(title = "Treatment"))+
  # facet_wrap(sigcount~time)+
  theme_bw()+
  xlab("")+
  ylab(expression("Log"[2]*" fold change"))+
  theme_bw()+
  facet_wrap(~time)+
  theme(plot.title = element_text(size = rel(1.5), hjust = 0.5),
        axis.title = element_text(size = 15, color = "black"),
        # axis.ticks = element_line(linewidth = 1.5),
        axis.line = element_line(linewidth = 1.5),
        strip.background = element_rect(fill = "transparent"),
        axis.text.x = element_blank(),
        strip.text.x = element_text(size = 12, color = "black", face = "bold"))

# drug_palNoVeh <- c("#8B006D" ,"#DF707E", "#F1B72B" ,"#3386DD", "#707031")


toplistall %>%
    mutate(id=factor(id, levels = c('DOX', 'EPI', 'DNR', 'MTX', 'TRZ','VEH'))) %>% 
  mutate(time= factor(time,
     levels=c("3_hours","24_hours"),
              label=c("3 hours","24 hours"))) %>%
  group_by(time, id) %>% 
  mutate(sigcount = if_else(adj.P.Val < 0.05,'sig','notsig'))%>%
  count(sigcount) %>% 
  pivot_wider(id_cols = c(time,id), names_from=sigcount, values_from=n) %>% 
  mutate(prop = sig/(sig+notsig)*100) %>% 
  mutate(prop=if_else(is.na(prop),0,prop)) %>% 
  ggplot(., aes(x=id, y= prop))+
  geom_col(aes(fill=id))+
  geom_text(aes(label = sprintf("%.2f",prop)),
            position=position_dodge(0.9),vjust=-.2 )+
  scale_fill_manual(values =drug_pal_fact)+
  guides(fill=guide_legend(title = "Treatment"))+
  facet_wrap(id~time)+#labeller = (time = facettimelabel) )+
  theme_bw()+
  xlab("")+
  ylab("Percentage of expressed genes")+
  theme_bw()+
  ggtitle("Percent DEGs (adj. P value <0.05)")+
  scale_y_continuous(expand=expansion(c(0.02,.2)))+
  theme(plot.title = element_text(size = rel(1.5), hjust = 0.5),
        axis.title = element_text(size = 15, color = "black"),
        # axis.ticks = element_line(linewidth = 1.5),
        axis.line = element_line(linewidth = 1.5),
        strip.background = element_rect(fill = "transparent"),
        axis.text.x = element_text(size = 8, color = "white", angle = 0),
        axis.text.y = element_text(size = 8, color = "black", angle = 0),
        strip.text.x = element_text(size = 12, color = "black", face = "bold"))

ggsave("output/Figures/Percent_DEG.eps",width = 6, height =4, units = "in")

Fig. S10

allfinal <- readRDS("output/allfinal_sup10.RDS") 
allfinal

allfinal3hour <- readRDS("data/allfinal3hour.RDS")
allfinal3hour

### Fig S10 Drug Specific Pathways

gostres3Dnrdeg_sp <- readRDS("data/DEG-GO/gostres3Dnrdeg_sp.RDS")

Dnr3_sp_DEGtable <- gostres3Dnrdeg_sp$result %>%
  dplyr::select(c(source, term_id,term_name,intersection_size, 
                   term_size, p_value))


Dnr3_sp_DEGtable  %>% 
    dplyr::filter(source=="GO:BP") %>% 
    dplyr::select(p_value,term_name,intersection_size) %>%
    slice_min(., n=10 ,order_by=p_value) %>%
    mutate(log_val = -log10(p_value)) %>%
   # slice_max(., n=10,order_by = p_value) %>%
   ggplot(., aes(x = log_val, y =reorder(term_name,p_value), col= intersection_size)) +
    geom_point(aes(size = intersection_size)) +
    scale_y_discrete(labels =scales::label_wrap(30))+
    guides(col="none", size=guide_legend(title = "# of intersected \n terms"))+
    ggtitle('DNR 3 hour specific(stringent)\n gene set GO:BP terms') +
    xlab(expression(" -"~log[10]~("adj. p-value")))+
    ylab("GO: BP term")+
    theme_bw()+
    theme(plot.title = element_text(size = rel(1.5), hjust = 0.5),
        axis.title = element_text(size = 15, color = "black"),
        axis.ticks = element_line(linewidth = 1.5),
        axis.line = element_line(linewidth = 1.5),
        axis.text = element_text(size = 10, color = "black", angle = 0),
        strip.text.x = element_text(size = 12, color = "black", face = "bold"))

gostres3Mtxdeg_sp <- readRDS("data/DEG-GO/gostres3Mtxdeg_sp.RDS")
Mtx3_sp_DEGtable <- gostres3Mtxdeg_sp$result %>%
  dplyr::select(c(source, term_id,term_name,intersection_size, 
                   term_size, p_value))
Mtx3_sp_DEGtable  %>% 
    dplyr::filter(source=="GO:BP") %>% 
    dplyr::select(p_value,term_name,intersection_size) %>%
    slice_min(., n=5,order_by=p_value) %>%
    mutate(log_val = -log10(p_value)) %>%
   # slice_max(., n=10,order_by = p_value) %>%
   ggplot(., aes(x = log_val, y =reorder(term_name,p_value), col= intersection_size)) +
    geom_point(aes(size = intersection_size)) +
    scale_y_discrete(labels = scales::label_wrap(30))+
  geom_vline(xintercept = (-log10(0.05)))+
    guides(col="none", size=guide_legend(title = "# of intersected \n terms"))+
    ggtitle('MTX 3 hour specific(stringent)\n gene set GO:BP terms') +
    xlab(expression(" -"~log[10]~("adj. p-value")))+
    ylab("GO: BP term")+
    theme_bw()+
    theme(plot.title = element_text(size = rel(1.5), hjust = 0.5),
        axis.title = element_text(size = 15, color = "black"),
        axis.ticks = element_line(linewidth = 1.5),
        axis.line = element_line(linewidth = 1.5),
        axis.text = element_text(size = 10, color = "black", angle = 0),
        strip.text.x = element_text(size = 12, color = "black", face = "bold"))

DX_sp_DEGgostres <- readRDS("data/DEG-GO/gostresDOXdeg_sp.RDS")
MT_sp_DEGgostres <- readRDS("data/DEG-GO/gostresMTXdeg_sp.RDS")

DX_sp_DEGtable <- DX_sp_DEGgostres$result %>%
  dplyr::select(c(source, term_id,term_name,intersection_size, 
                   term_size, p_value))
MT_sp_DEGtable <- MT_sp_DEGgostres$result %>%
  dplyr::select(c(source, term_id,term_name,intersection_size, 
                   term_size, p_value))
  
  
DX_sp_DEGtable  %>% 
    dplyr::filter(source=="GO:BP") %>% 
    dplyr::select(p_value,term_name,intersection_size) %>%
    slice_min(., n=10 ,order_by=p_value) %>%
    mutate(log_val = -log10(p_value)) %>%
   # slice_max(., n=10,order_by = p_value) %>%
   ggplot(., aes(x = log_val, y =reorder(term_name,p_value), col= intersection_size)) +
    geom_point(aes(size = intersection_size)) +
    scale_y_discrete(labels = scales::wrap_format(30))+
    guides(col="none", size=guide_legend(title = "# of intersected \n terms"))+
    ggtitle('DOX specific 24 hour gene set GO:BP terms') +
    xlab(expression(" -"~log[10]~("adj. p-value")))+
    ylab("GO: BP term")+
    theme_bw()+
    theme(plot.title = element_text(size = rel(1.5), hjust = 0.5),
        axis.title = element_text(size = 15, color = "black"),
        axis.ticks = element_line(linewidth = 1.5),
        axis.line = element_line(linewidth = 1.5),
        axis.text = element_text(size = 10, color = "black", angle = 0),
        strip.text.x = element_text(size = 12, color = "black", face = "bold"))

MT_sp_DEGtable  %>% 
    dplyr::filter(source=="GO:BP") %>% 
    dplyr::select(p_value,term_name,intersection_size) %>%
    slice_min(., n=10 ,order_by=p_value) %>%
    mutate(log_val = -log10(p_value)) %>%
   # slice_max(., n=10,order_by = p_value) %>%
   ggplot(., aes(x = log_val, y =reorder(term_name,p_value), col= intersection_size)) +
    geom_point(aes(size = intersection_size)) +
    scale_y_discrete(labels = scales::wrap_format(30))+
    guides(col="none", size=guide_legend(title = "# of intersected \n terms"))+
    ggtitle('MTX specific 24 hour gene set GO:BP terms') +
    xlab(expression(" -"~log[10]~("adj. p-value")))+
    ylab("GO: BP term")+
    theme_bw()+
    theme(plot.title = element_text(size = rel(1.5), hjust = 0.5),
        axis.title = element_text(size = 15, color = "black"),
        axis.ticks = element_line(linewidth = 1.5),
        axis.line = element_line(linewidth = 1.5),
        axis.text = element_text(size = 10, color = "black", angle = 0),
        strip.text.x = element_text(size = 12, color = "black", face = "bold"))

Fig. S12

DNRvenn<- readRDS ("output/DNRvenn.RDS")
DOXvenn<- readRDS ("output/DOXvenn.RDS")
EPIvenn<- readRDS ("output/EPIvenn.RDS")
MTXvenn<- readRDS ("output/MTXvenn.RDS")

plot_grid(DNRvenn,DOXvenn,EPIvenn,MTXvenn,nrow=2, ncol = 2)

Fig. S12

cormotif_initial <- readRDS("data/cormotif_initialall.RDS")
Cormotif::plotIC(cormotif_initial)

motif_NRrep <-  readRDS("output/motif_NRrep.RDS")
motif_ERrep <-  readRDS("output/motif_ERrep.RDS")
motif_TIrep <-  readRDS("output/motif_TI_rep.RDS")
motif_LRrep <-  readRDS("output/motif_LRrep.RDS")
motif_NRrep <- motif_NRrep +
  scale_y_continuous(labels = scales::number_format(accuracy = 0.1))+
  theme(legend.position = "NULL", axis.title.y =element_text(size =12))

motif_ERrep <- motif_ERrep+
  scale_y_continuous(labels = scales::number_format(accuracy = 0.1))+
  theme(legend.position = "NULL", axis.title.y =element_text(size =12))

motif_TIrep <- motif_TIrep+
  scale_y_continuous(labels = scales::number_format(accuracy = 0.1))+ 
  theme(legend.position = "NULL", axis.title.y =element_text(size =12))

motif_LRrep <- motif_LRrep+
  scale_y_continuous(labels = scales::number_format(accuracy = 0.1))+
  theme(legend.position = "NULL", axis.title.y =element_text(size =12))
plot_grid(motif_ERrep,motif_TIrep,motif_LRrep,motif_NRrep,nrow = 4,ncol = 1)

<environment: R_GlobalEnv>

Fig. S15

gene_corr_frame <- readRDS("data/gene_corr_frame.RDS")
GOI_genelist <- read.csv("output/GOI_genelist.txt",row.names = 1)

for (gene in GOI_genelist$entrezgene_id){
    gene_plot <- gene_corr_frame %>% 
      dplyr::filter(entrezgene_id == gene) %>%
      ggplot(., aes(x=tox, y=counts))+
      geom_point(aes(col=indv))+
      geom_smooth(method="lm")+
      facet_wrap(hgnc_symbol~Drug, scales="free")+
      theme_classic()+
      xlab("Toxicity score") +
      ylab(expression("counts in log"[2]*" cpm")) +
      ggtitle(expression(paste("Correlation between counts and toxicity by drug")))+
      scale_color_brewer(palette = "Dark2",name = "Individual", label = c("1","2","3","4","5","6"))+
      scale_y_continuous(labels = scales::number_format(accuracy = 0.01))+
      stat_cor(method="pearson",
               cor.coef.name="rho",
               aes(label = paste(..r.label.., ..p.label.., sep = "~`,`~")),
               color = "red",
               label.x.npc = 0.01,
               label.y.npc=0.01, 
               size = 3)+
      theme(plot.title = element_text(size = rel(1.5), hjust = 0.5,face = "bold"),
            axis.title = element_text(size = 15, color = "black"),
            axis.ticks = element_line(size = 1.5),
            axis.text = element_text(size = 8, color = "black", angle = 20),
            strip.text.x = element_text(size = 10, color = "black", face = "italic"))
   print(gene_plot)
   
 }


sessionInfo()
R version 4.3.1 (2023-06-16 ucrt)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19045)

Matrix products: default


locale:
[1] LC_COLLATE=English_United States.utf8 
[2] LC_CTYPE=English_United States.utf8   
[3] LC_MONETARY=English_United States.utf8
[4] LC_NUMERIC=C                          
[5] LC_TIME=English_United States.utf8    

time zone: America/Chicago
tzcode source: internal

attached base packages:
[1] grid      stats     graphics  grDevices utils     datasets  methods  
[8] base     

other attached packages:
 [1] edgeR_3.42.4          limma_3.56.2          data.table_1.14.8    
 [4] drc_3.0-1             MASS_7.3-60           cowplot_1.1.1        
 [7] gridExtra_2.3         ComplexHeatmap_2.16.0 RColorBrewer_1.1-3   
[10] ggsignif_0.6.4        zoo_1.8-12            rstatix_0.7.2        
[13] ggpubr_0.6.0          lubridate_1.9.2       forcats_1.0.0        
[16] stringr_1.5.0         dplyr_1.1.2           purrr_1.0.1          
[19] readr_2.1.4           tidyr_1.3.0           tibble_3.2.1         
[22] ggplot2_3.4.2         tidyverse_2.0.0       workflowr_1.7.0      

loaded via a namespace (and not attached):
  [1] rstudioapi_0.15.0     jsonlite_1.8.7        shape_1.4.6          
  [4] magrittr_2.0.3        TH.data_1.1-2         magick_2.7.4         
  [7] farver_2.1.1          rmarkdown_2.23        zlibbioc_1.46.0      
 [10] GlobalOptions_0.1.2   fs_1.6.3              ragg_1.2.5           
 [13] vctrs_0.6.3           htmltools_0.5.5       plotrix_3.8-2        
 [16] broom_1.0.5           sass_0.4.7            KernSmooth_2.23-22   
 [19] bslib_0.5.0           sandwich_3.0-2        cachem_1.0.8         
 [22] whisker_0.4.1         lifecycle_1.0.3       iterators_1.0.14     
 [25] pkgconfig_2.0.3       Matrix_1.6-0          R6_2.5.1             
 [28] fastmap_1.1.1         clue_0.3-64           digest_0.6.33        
 [31] colorspace_2.1-0      S4Vectors_0.38.1      ps_1.7.5             
 [34] rprojroot_2.0.3       textshaping_0.3.6     labeling_0.4.2       
 [37] fansi_1.0.4           timechange_0.2.0      httr_1.4.6           
 [40] abind_1.4-5           mgcv_1.9-0            compiler_4.3.1       
 [43] proxy_0.4-27          withr_2.5.0           doParallel_1.0.17    
 [46] backports_1.4.1       carData_3.0-5         DBI_1.1.3            
 [49] highr_0.10            rjson_0.2.21          classInt_0.4-9       
 [52] gtools_3.9.4          tools_4.3.1           units_0.8-2          
 [55] httpuv_1.6.11         Cormotif_1.46.0       glue_1.6.2           
 [58] callr_3.7.3           nlme_3.1-162          promises_1.2.0.1     
 [61] sf_1.0-14             getPass_0.2-2         cluster_2.1.4        
 [64] generics_0.1.3        gtable_0.3.3          tzdb_0.4.0           
 [67] preprocessCore_1.62.1 class_7.3-22          hms_1.1.3            
 [70] ggVennDiagram_1.2.2   car_3.1-2             utf8_1.2.3           
 [73] BiocGenerics_0.46.0   foreach_1.5.2         pillar_1.9.0         
 [76] later_1.3.1           circlize_0.4.15       splines_4.3.1        
 [79] lattice_0.21-8        survival_3.5-5        tidyselect_1.2.0     
 [82] locfit_1.5-9.8        knitr_1.43            git2r_0.32.0         
 [85] IRanges_2.34.1        stats4_4.3.1          xfun_0.39            
 [88] Biobase_2.60.0        matrixStats_1.0.0     stringi_1.7.12       
 [91] yaml_2.3.7            evaluate_0.21         codetools_0.2-19     
 [94] BiocManager_1.30.21.1 RVenn_1.1.0           affyio_1.70.0        
 [97] cli_3.6.1             systemfonts_1.0.4     munsell_0.5.0        
[100] processx_3.8.2        jquerylib_0.1.4       Rcpp_1.0.11          
[103] png_0.1-8             parallel_4.3.1        viridisLite_0.4.2    
[106] mvtnorm_1.2-2         affy_1.78.2           scales_1.2.1         
[109] e1071_1.7-13          crayon_1.5.2          GetoptLong_1.0.5     
[112] rlang_1.1.1           multcomp_1.4-25