Data Setup

Import DGElist Data

GO Analysis

Visualisation
Visualisation
Visualisation

Export Data

Last updated: 2023-01-20

Checks: 6 1

Knit directory: SRB_2022/1_analysis/

This reproducible R Markdown analysis was created with workflowr (version 1.7.0). The Checks tab describes the reproducibility checks that were applied when the results were created. The Past versions tab lists the development history.

R Markdown file: uncommitted changes

The R Markdown file has unstaged changes. To know which version of the R Markdown file created these results, you’ll want to first commit it to the Git repo. If you’re still working on the analysis, you can ignore this warning. When you’re finished, you can run wflow_publish to commit the R Markdown file and build the HTML.

Environment: empty

Great job! The global environment was empty. Objects defined in the global environment can affect the analysis in your R Markdown file in unknown ways. For reproduciblity it’s best to always run the code in an empty environment.

Seed: set.seed(12345)

The command set.seed(12345) was run prior to running the code in the R Markdown file. Setting a seed ensures that any results that rely on randomness, e.g. subsampling or permutations, are reproducible.

Session information: recorded

Great job! Recording the operating system, R version, and package versions is critical for reproducibility.

Cache: none

Nice! There were no cached chunks for this analysis, so you can be confident that you successfully produced the results during this run.

File paths: relative

Great job! Using relative paths to the files within your workflowr project makes it easier to run your code on other machines.

Repository version: 6e0f643

Great! You are using Git for version control. Tracking code development and connecting the code version to the results is critical for reproducibility.

The results in this page were generated with repository version 6e0f643. See the Past versions tab to see a history of the changes made to the R Markdown and HTML files.

Note that you need to be careful to ensure that all relevant files for the analysis have been committed to Git prior to generating the results (you can use wflow_publish or wflow_git_commit). workflowr only checks the R Markdown file, but you know if there are other scripts or data files that it depends on. Below is the status of the Git repository when the results were generated:


Ignored files:
    Ignored:    .Rhistory
    Ignored:    .Rproj.user/

Untracked files:
    Untracked:  .gitignore
    Untracked:  test plz delete me.Rmd
    Untracked:  test-plz-delete-me.html

Unstaged changes:
    Modified:   0_data/RDS_objects/enrichGO_sig.rds
    Modified:   1_analysis/_site.yml
    Modified:   1_analysis/deAnalysis.Rmd
    Modified:   1_analysis/go.Rmd
    Modified:   1_analysis/index.Rmd
    Modified:   1_analysis/kegg.Rmd
    Modified:   1_analysis/reactome.Rmd
    Modified:   1_analysis/setUp.Rmd
    Modified:   2_plots/de/ma_1.05.png
    Modified:   2_plots/de/ma_1.1.png
    Modified:   2_plots/de/ma_1.5.png
    Modified:   2_plots/go/bp_dot_1.05.svg
    Modified:   2_plots/go/bp_dot_1.1.svg
    Modified:   2_plots/go/bp_dot_1.5.svg
    Modified:   2_plots/go/cc_dot_1.05.svg
    Modified:   2_plots/go/cc_dot_1.1.svg
    Modified:   2_plots/go/cc_dot_1.5.svg
    Modified:   2_plots/go/mf_dot_1.05.svg
    Modified:   2_plots/go/mf_dot_1.1.svg
    Modified:   2_plots/go/mf_dot_1.5.svg
    Deleted:    2_plots/ipa/funct_cat_alluvial.svg
    Deleted:    2_plots/ipa/up_cat_alluvial.svg
    Deleted:    2_plots/ipa/upstream_funct_alluvial.svg
    Modified:   2_plots/kegg/kegg_dot_1.05.svg
    Modified:   2_plots/kegg/kegg_dot_1.1.svg
    Modified:   2_plots/kegg/kegg_dot_1.5.svg
    Deleted:    2_plots/reactome/combine_GO.svg
    Modified:   2_plots/reactome/react_dot_1.05.svg
    Modified:   2_plots/reactome/react_dot_1.1.svg
    Modified:   2_plots/reactome/react_dot_1.5.svg
    Deleted:    2_plots/reactome/react_dot_INT vs CONT.svg
    Deleted:    2_plots/reactome/react_dot_INT vs SVX_VAS.svg
    Deleted:    2_plots/reactome/react_dot_SVX vs SVX_VAS.svg
    Deleted:    2_plots/reactome/react_dot_VAS vs SVX_VAS.svg
    Modified:   2_plots/reactome/upset_react_1.05.svg
    Modified:   2_plots/reactome/upset_react_1.1.svg
    Modified:   2_plots/reactome/upset_react_1.5.svg
    Deleted:    2_plots/reactome/upset_react_INT vs CONT.svg
    Deleted:    2_plots/reactome/upset_react_INT vs SVX_VAS.svg
    Deleted:    2_plots/reactome/upset_react_SVX vs SVX_VAS.svg
    Deleted:    2_plots/reactome/upset_react_VAS vs SVX_VAS.svg
    Modified:   3_output/enrichKEGG_all.xlsx
    Modified:   3_output/enrichKEGG_sig.xlsx
    Modified:   3_output/lmTreat_all.xlsx
    Modified:   3_output/lmTreat_fc1.5_voom2_all_fdr.xlsx
    Modified:   3_output/lmTreat_sig.xlsx

Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes.

These are the previous versions of the repository in which changes were made to the R Markdown (1_analysis/go.Rmd) and HTML (docs/go.html) files. If you’ve configured a remote Git repository (see ?wflow_git_remote), click on the hyperlinks in the table below to view the files as they were in that past version.

File	Version	Author	Date	Message
html	691cf34	Ha Manh Tran	2023-01-20	Build site.
Rmd	7f6bab2	Ha Manh Tran	2023-01-20	workflowr::wflow_publish(here::here("1_analysis/*.Rmd"))
Rmd	b6cf190	tranmanhha135	2023-01-19	quick commit
Rmd	3119fad	tranmanhha135	2022-11-05	build website
html	3119fad	tranmanhha135	2022-11-05	build website

Data Setup

# working with data
library(dplyr)
library(magrittr)
library(readr)
library(tibble)
library(reshape2)
library(tidyverse)

# Visualisation:
library(kableExtra)
library(ggplot2)
library(grid)

# Custom ggplot
library(gridExtra)
library(ggbiplot)
library(ggrepel)


# Bioconductor packages:
library(edgeR)
library(limma)
library(Glimma)
library(clusterProfiler)
library(org.Mm.eg.db)
library(enrichplot)

theme_set(theme_minimal())
pub <- readRDS(here::here("0_data/RDS_objects/pub.rds"))

Import DGElist Data

DGElist object containing the raw feature count, sample metadata, and gene metadata, created in the Set Up stage.

# load DGElist previously created in the set up
dge <- readRDS(here::here("0_data/RDS_objects/dge.rds"))
fc <- readRDS(here::here("0_data/RDS_objects/fc.rds"))
lfc <- readRDS(here::here("0_data/RDS_objects/lfc.rds"))
lmTreat <- readRDS(here::here("0_data/RDS_objects/lmTreat.rds"))
lmTreat_sig <- readRDS(here::here("0_data/RDS_objects/lmTreat_sig.rds"))

GO Analysis

goSummaries is a package created by Dr Stephen Pederson for filtering GO terms based on ontology level.

# circumvent rerunning of lengthy analysis.
enrichGO <- readRDS(here::here("0_data/RDS_objects/enrichGO.rds"))
enrichGO_sig <- readRDS(here::here("0_data/RDS_objects/enrichGO_sig.rds"))

# download go summaries and set the minimum ontology level
goSummaries <- url("https://uofabioinformaticshub.github.io/summaries2GO/data/goSummaries.RDS") %>%
  readRDS()
minPath <- 3

enrichGO=list()
enrichGO_sig <- list()
for (i in 1:length(fc)) {
  x <- fc[i] %>% as.character()
  # find enriched GO terms
  enrichGO[[x]] <- clusterProfiler::enrichGO(
    gene = lmTreat_sig[[x]]$entrezid,
    OrgDb = org.Mm.eg.db,
    keyType = "ENTREZID",
    ont = "ALL",
    pAdjustMethod = "fdr",
    pvalueCutoff = 0.05
  )

  # bind to goSummaries to elminate go terms with ontology levels 1 and 2.
  enrichGO_sig[[x]] <- enrichGO[[x]] %>% 
    clusterProfiler::setReadable(OrgDb = org.Mm.eg.db, keyType = "auto")

  enrichGO_sig[[x]] <- enrichGO_sig[[x]] %>%
    as.data.frame() %>%
    rownames_to_column("id") %>%
    left_join(goSummaries) %>%
    dplyr::filter(shortest_path >= minPath) %>%
    column_to_rownames("id")

  # adjust go results, separate compound column, add FDR column, adjust the GeneRatio column
  enrichGO_sig[[x]] <- enrichGO_sig[[x]] %>%
    separate(col = BgRatio, sep = "/", into = c("Total", "Universe")) %>%
    dplyr::mutate(
      logFDR = -log(p.adjust, 10),
      GeneRatio = Count / as.numeric(Total)) %>% 
    dplyr::select(c("Description", "ontology", "GeneRatio", "pvalue", "p.adjust", "logFDR", "qvalue", "geneID", "Count"))
  
  # at the beginnning of a word (after 35 characters), add a newline. shorten the y axis for dot plot 
  # enrichGO_sig[[x]]$Description <- sub(pattern = "(.{1,35})(?:$| )", 
  #                                      replacement = "\\1\n", 
  #                                      x = enrichGO_sig[[x]]$Description)
  
  # # remove the additional newline at the end of the string
  # enrichGO_sig[[x]]$Description <- sub(pattern = "\n$", 
  #                                      replacement = "", 
  #                                      x = enrichGO_sig[[x]]$Description)
}

# display the top 30 most sig
enrichGO_sig[[1]] %>% 
  dplyr::mutate_if(is.numeric, funs(as.character(signif(.,3)))) %>% 
  kable(caption = "Significantly enriched GO terms") %>%
  kable_styling(bootstrap_options = c("striped", "hover")) %>%
  scroll_box(height = "600px")

Significantly enriched GO terms
	Description	ontology	GeneRatio	pvalue	p.adjust	logFDR	qvalue	geneID	Count
GO:0030198	extracellular matrix organization	BP	0.21	2e-24	5.36e-21	20.3	3.47e-21	Col11a1/Ihh/Cyp1b1/Mmp16/Hmcn1/Sfrp2/Vit/Sema5a/Scara3/Col14a1/Ddr2/Adamts20/Col4a6/Prdm5/Phldb2/Npnt/Spock2/Ets1/Col16a1/Tgfbi/Adamts16/Adamts19/Fn1/Mmp2/Foxf1/Fkbp10/Nid1/Olfml2b/Has2/Egflam/Adamts1/Col9a2/Col13a1/Postn/Loxl3/Adamts10/Smoc1/Emilin1/Tnfrsf11b/Tie1/Col5a2/Ndnf/Adamts7/Ltbp3/Mmp19/Col15a1/Adamtsl1/P3h1/Vwa1/Abi3bp/Dpt/Ccn2/Efemp2/Crtap/Olfml2a/Cav1/Ntng1/Col23a1/Col18a1/Itga8/Adamts17/Lum/Ccdc80/Fbln5/Col4a5/Eng	66
GO:0043062	extracellular structure organization	BP	0.209	2.41e-24	5.36e-21	20.3	3.47e-21	Col11a1/Ihh/Cyp1b1/Mmp16/Hmcn1/Sfrp2/Vit/Sema5a/Scara3/Col14a1/Ddr2/Adamts20/Col4a6/Prdm5/Phldb2/Npnt/Spock2/Ets1/Col16a1/Tgfbi/Adamts16/Adamts19/Fn1/Mmp2/Foxf1/Fkbp10/Nid1/Olfml2b/Has2/Egflam/Adamts1/Col9a2/Col13a1/Postn/Loxl3/Adamts10/Smoc1/Emilin1/Tnfrsf11b/Tie1/Col5a2/Ndnf/Adamts7/Ltbp3/Mmp19/Col15a1/Adamtsl1/P3h1/Vwa1/Abi3bp/Dpt/Ccn2/Efemp2/Crtap/Olfml2a/Cav1/Ntng1/Col23a1/Col18a1/Itga8/Adamts17/Lum/Ccdc80/Fbln5/Col4a5/Eng	66
GO:0045229	external encapsulating structure organization	BP	0.208	2.91e-24	5.36e-21	20.3	3.47e-21	Col11a1/Ihh/Cyp1b1/Mmp16/Hmcn1/Sfrp2/Vit/Sema5a/Scara3/Col14a1/Ddr2/Adamts20/Col4a6/Prdm5/Phldb2/Npnt/Spock2/Ets1/Col16a1/Tgfbi/Adamts16/Adamts19/Fn1/Mmp2/Foxf1/Fkbp10/Nid1/Olfml2b/Has2/Egflam/Adamts1/Col9a2/Col13a1/Postn/Loxl3/Adamts10/Smoc1/Emilin1/Tnfrsf11b/Tie1/Col5a2/Ndnf/Adamts7/Ltbp3/Mmp19/Col15a1/Adamtsl1/P3h1/Vwa1/Abi3bp/Dpt/Ccn2/Efemp2/Crtap/Olfml2a/Cav1/Ntng1/Col23a1/Col18a1/Itga8/Adamts17/Lum/Ccdc80/Fbln5/Col4a5/Eng	66
GO:0045785	positive regulation of cell adhesion	BP	0.164	8.25e-22	1.14e-18	17.9	7.39e-19	Ihh/Efnb3/Vit/Col26a1/Angpt1/Mdk/Lef1/Itga4/Cd83/Kdr/Igf1/Npnt/Nrp1/Chst2/Cd44/Fermt2/Spock2/Ets1/Col16a1/Fn1/Foxf1/Icam1/Nid1/Tek/Cdh13/Cxcl12/Has2/Egflam/Pik3r6/Gli3/Podxl/Calca/Thy1/Plpp3/Tnfsf13b/Coro1a/Cd1d1/Ppm1f/Smoc1/Itgal/H2-Ab1/Il27ra/Emilin1/Vegfc/Sox12/Havcr2/H2-Ob/Sele/Igf2/Ndnf/Dysf/Nckap1l/Xcl1/Pcsk5/H2-Eb1/Stat5b/Net1/Abi3bp/Adam19/H2-Aa/Gimap5/Efemp2/St3gal4/Zap70/Gimap3/Apbb1ip/Ptn/Il12rb1/Cav1/Pld2/Il2rg/Hacd1/Spn/Enpp2/Bmp7/Il7r/Cd4/Rasal3/Ccdc80	79
GO:0006816	calcium ion transport	BP	0.166	1.48e-20	1.64e-17	16.8	1.06e-17	Nalcn/Cacna1c/Ryr1/Jph4/Spink1/Igf1/Adra1a/Slc8a1/Nos3/Drd4/Cachd1/Cacna2d1/Ednrb/Myo5a/Slc24a4/Icam1/Grin2b/Prkd1/Stc1/Cxcr3/Cxcl12/Slc24a3/Cacna1e/Ank2/Slc8a3/Calca/Trpc6/Thy1/Nalf1/Coro1a/Gja4/Aplnr/Cracr2a/Agtr1a/Ednra/Dysf/Bin1/Adcyap1r1/Htr2a/Xcl1/Pkd1/Tspan13/Cacng7/Stac2/Selenon/Arrb2/Asph/Pkd2/Fyn/Xcr1/Ryr3/Cd84/Rrad/Calcrl/Cacna1h/Slc25a23/Ptger3/Atp2b4/Ccn2/Gnb5/Gimap5/Gstm7/Atp1a2/Gimap3/Psen1/Sri/Pdgfrb/Cav1/Cacna1a/Usp2/Cacnb4/F2r/Cd4	73
GO:0050808	synapse organization	BP	0.156	6.02e-20	5.55e-17	16.3	3.59e-17	Gpc6/Gap43/Sdk2/Lrrc4c/Plxnb1/Ptprd/St8sia2/Nlgn1/Nrp1/Ptpro/Rims3/Pdzrn3/P2rx2/Cdh2/Wasf3/Lrrk2/Lrrc4b/Myo5a/Mef2c/Pfn2/Nptx1/Grin2b/Shank2/Pcdhgc3/Obsl1/Adgrl1/Ppfia2/Slc8a3/Slitrk3/Plxnd1/Dock10/Glrb/Abi2/Kif1a/Ppfia4/Palld/Epha3/Nlgn3/Dgkb/Nptxr/Apoe/Arhgef15/Nfasc/Magi2/Prrt1/Sparcl1/Caprin2/Pcdh17/Nfatc4/Epha7/Bhlhb9/Erc2/Lrfn2/Fyn/Dlg4/Cux2/Palm/Dlg5/Syngap1/Ngef/Arhgef9/Rab39b/Psen1/Ptn/Ntng1/Cacna1a/Pcdhgc4/Dact1/Iqsec3/Zmynd8/Cacnb4/F2r/Lrp4/Camk1/Nlgn2/Zfp365/Col4a5	77
GO:0034329	cell junction assembly	BP	0.161	2.8e-19	2.21e-16	15.7	1.43e-16	Gpc6/Gap43/Sdk2/Wnt11/Kdr/Plxnb1/Ptprd/St8sia2/Nlgn1/Epb41l3/Phldb2/Mpdz/Nrp1/Ptpro/Fermt2/Col16a1/Cdh2/Fn1/Lrrc4b/Cdh6/Mef2c/Nptx1/Jam3/Thsd1/Tek/Shank2/Obsl1/Adgrl1/Cldn8/Cdh10/Slitrk3/Myo9a/Plxnd1/Cdh5/Thy1/Abi2/Ppm1f/Epha3/Aplnr/Esam/Nlgn3/Sh3bp1/Limch1/Arhgap6/Nptxr/Nfasc/Cdh11/Magi2/Gjc1/Pecam1/Snai1/Pcdh17/Epha7/Heg1/Dlc1/Dchs1/Bhlhb9/Nphp1/Cldn5/Cux2/Dlg5/Arhgef9/Hipk1/Cav1/Cacna1a/Itgb4/Pdcd6ip/Enpp2/Cldn1/Lrp4/Nlgn2	71
GO:0031589	cell-substrate adhesion	BP	0.166	1.09e-17	7.51e-15	14.1	4.87e-15	Ptprz1/Vit/Col26a1/Angpt1/Mdk/Itga4/Kdr/Phldb2/Npnt/Nrp1/Lamc3/Fermt2/Spock2/Col16a1/Itgb7/Fn1/Foxf1/Nid1/Jam3/Thsd1/Tek/Cdh13/Has2/Egflam/Itga1/Col13a1/Frem1/Thy1/Postn/Coro1a/Ppm1f/Smoc1/Epha3/Itgal/Limch1/Arhgap6/Emilin1/Vegfc/Sned1/Hoxd3/Pecam1/Tmeff2/Ndnf/Itga7/Parvg/Pcsk5/Parvb/Dlc1/Epdr1/Net1/Abi3bp/Ccn2/Efemp2/Ptn/Cd96/Ntng1/Itga8/Itgb4/Hacd1/Enpp2/Nid2/Ccdc80	62
GO:0048754	branching morphogenesis of an epithelial tube	BP	0.224	1.64e-17	1.01e-14	14	6.52e-15	Ihh/Sfrp2/Sema5a/Wnt6/Ar/Angpt1/Hhip/Mdk/Lef1/Hoxd11/Kdr/Nog/Igf1/Tbx2/Npnt/Nrp1/Cd44/Hoxa11/Adamts16/Gpc3/Areg/Foxf1/Tek/Cxcl12/Tcf21/Gli3/Plxnd1/Gdf7/Mgp/Agtr1a/Tbx3/Rasip1/Tie1/Ednra/Pkd1/Nfatc4/Ptch1/Dchs1/Dlg5/Fat4/Bmp7/Myc/Eng	43
GO:0007224	smoothened signaling pathway	BP	0.245	1.86e-17	1.03e-14	14	6.67e-15	Gli1/Ihh/Hhip/Evc2/Nog/Ptch2/Evc/Kif7/Arl6/Dzip1l/Gpc3/Foxf1/Cibar1/Serpine2/Bbs7/Armc9/Zfp423/Gli3/Ptpdc1/Ift57/Wnt9a/Rab34/Gpr161/Enpp1/Dync2h1/Hipk2/Cfap410/Ttc26/Arl3/Ptch1/Tmem231/Ttbk2/Rab23/Dzip1/Dlg5/Glis2/Hipk1/Gpc2/Ift81	39
GO:0001655	urogenital system development	BP	0.16	6.83e-17	3.15e-14	13.5	2.04e-14	Stra6/Wnt6/Ar/Angpt1/Wnt11/Pygo1/Hoxd11/Cyp7b1/Nog/Igf1/Npnt/Nrp1/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Lrrk2/Ednrb/Mmp2/Mef2c/Foxf1/Id3/Id4/Osr2/Nid1/Enpep/Tek/Gdf11/Adamts1/Tcf21/Gli3/Plxnd1/Lrp2/Tshz3/Prdm1/Cplane1/Enpp1/Cdkn1c/Agtr1a/Dync2h1/Ednra/Heyl/Pkd1/Pcsk5/Arl3/Smad9/Epha7/Ptch1/Dchs1/Osr1/Pkd2/Aqp11/Dlg5/Fat4/Pdgfrb/Glis2/Itga8/Bmp7/Lrp4/Vcan/Myc	62
GO:0001822	kidney development	BP	0.17	1.62e-16	6.88e-14	13.2	4.46e-14	Stra6/Wnt6/Angpt1/Wnt11/Pygo1/Hoxd11/Nog/Npnt/Nrp1/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Lrrk2/Ednrb/Mef2c/Id3/Osr2/Nid1/Enpep/Tek/Gdf11/Adamts1/Tcf21/Gli3/Plxnd1/Lrp2/Tshz3/Prdm1/Cplane1/Enpp1/Cdkn1c/Agtr1a/Dync2h1/Ednra/Heyl/Pkd1/Pcsk5/Arl3/Smad9/Epha7/Ptch1/Dchs1/Osr1/Pkd2/Aqp11/Dlg5/Fat4/Pdgfrb/Glis2/Itga8/Bmp7/Lrp4/Vcan/Myc	56
GO:0072001	renal system development	BP	0.165	3e-16	1.11e-13	13	7.2e-14	Stra6/Wnt6/Angpt1/Wnt11/Pygo1/Hoxd11/Nog/Npnt/Nrp1/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Lrrk2/Ednrb/Mef2c/Foxf1/Id3/Osr2/Nid1/Enpep/Tek/Gdf11/Adamts1/Tcf21/Gli3/Plxnd1/Lrp2/Tshz3/Prdm1/Cplane1/Enpp1/Cdkn1c/Agtr1a/Dync2h1/Ednra/Heyl/Pkd1/Pcsk5/Arl3/Smad9/Epha7/Ptch1/Dchs1/Osr1/Pkd2/Aqp11/Dlg5/Fat4/Pdgfrb/Glis2/Itga8/Bmp7/Lrp4/Vcan/Myc	57
GO:0034765	regulation of ion transmembrane transport	BP	0.141	7.76e-16	2.58e-13	12.6	1.67e-13	Kcnb2/Nalcn/Kcnj3/Cacna1c/Hecw2/Kcna6/Kcnd2/Kcnd3/Nlgn1/Tcaf1/Slc8a1/Scn4b/Drd4/Fxyd5/Scn1a/Cacna2d1/Kcnq5/Myo5a/Mef2c/Prkd1/Cxcr3/Cacna1e/Ank2/Edn3/Plcb1/Trpc6/Thy1/Coro1a/Scn2a/Aplnr/Nlgn3/Cracr2a/Agtr1a/Prrt1/Kcnma1/Ednra/Kcnc4/Dysf/Bin1/Tspan13/Cacng7/Stac2/Kcnip3/Selenon/Asph/Osr1/Pkd2/Fhl1/Fyn/Rrad/Cacna1h/Dlg4/Kcng4/Ptger3/Atp2b4/Scn3a/Gnb5/Gstm7/Atp1a2/Psen1/Abcb1a/Sri/Cav1/Kcnq4/Cacna1a/Cacnb4/F2r/Kcnh1/Twist1/Nlgn2	70
GO:0001667	ameboidal-type cell migration	BP	0.146	7.94e-16	2.58e-13	12.6	1.67e-13	Cyp1b1/Sema5a/Angpt1/Wnt11/Itga4/Kdr/Igf1/Evl/Zeb2/Ddr2/Sema5b/Slc8a1/Nos3/Nrp1/Sema7a/Ets1/Cdh2/Itgb7/Fn1/Ednrb/Mef2c/Pfn2/Ptp4a3/Prkd1/Stc1/Tek/Cdh13/Cxcl12/Has2/Akap12/Vash1/Edn3/Ptprm/Calca/Plxnd1/Cdh5/Syde1/Plpp3/Ppm1f/Kit/Jcad/Sh3bp1/Vegfc/Prr5l/Apoe/Ednra/Sema3g/Daam2/Pecam1/Igf2/Kitl/Hdac9/Akt3/Atp2b4/Fstl1/Arsb/Adgra2/Sema6a/Mapre2/Cygb/Itgb4/Enpp2/Bmp7/Hand2/Twist1/Plekhg5	66
GO:0048736	appendage development	BP	0.206	9.52e-16	2.77e-13	12.6	1.79e-13	Ihh/Sfrp2/Cacna1c/Lef1/Hoxd10/Hoxd11/Nog/Aff3/Pkdcc/Tbx2/Rnf165/Fermt2/Hoxa11/Gpc3/Hoxd9/Hoxa10/Cibar1/Osr2/Bbs7/Flvcr1/Gli3/Wnt9a/Smoc1/Cplane1/Enpp1/Tbx3/Dync2h1/Pcsk5/Hoxa9/Ptch1/Tmem231/Asph/Osr1/Ttbk2/Rab23/Psen1/Itgb4/Iqce/Bmp7/Lrp4/Hand2/Twist1	42
GO:0060173	limb development	BP	0.206	9.52e-16	2.77e-13	12.6	1.79e-13	Ihh/Sfrp2/Cacna1c/Lef1/Hoxd10/Hoxd11/Nog/Aff3/Pkdcc/Tbx2/Rnf165/Fermt2/Hoxa11/Gpc3/Hoxd9/Hoxa10/Cibar1/Osr2/Bbs7/Flvcr1/Gli3/Wnt9a/Smoc1/Cplane1/Enpp1/Tbx3/Dync2h1/Pcsk5/Hoxa9/Ptch1/Tmem231/Asph/Osr1/Ttbk2/Rab23/Psen1/Itgb4/Iqce/Bmp7/Lrp4/Hand2/Twist1	42
GO:0031345	negative regulation of cell projection organization	BP	0.2	1.31e-15	3.61e-13	12.4	2.34e-13	Efnb3/Ptprz1/Map2/Sema5a/Evl/Sema5b/Nlgn1/Nrp1/Sema7a/Cspg4/Lrrk2/Ntm/Abi3/Dab1/Pfn2/Grin2b/Trpc6/Thy1/Epha3/Minar1/Nlgn3/Tsku/Cd38/Apoe/Sema3g/Dennd5a/Nfatc4/Rtn4rl1/Epha7/Neo1/Fyn/Fat3/Xylt1/Dpysl3/Syngap1/Cep97/Ngef/Psen1/Sema6a/Ulk2/Lrp4/Draxin/Zfp365	43
GO:0060562	epithelial tube morphogenesis	BP	0.152	2.68e-15	7.05e-13	12.2	4.57e-13	Ihh/Sfrp2/Sema5a/Wnt6/Ar/Angpt1/Hhip/Mdk/Lef1/Hoxd11/Kdr/Nog/Igf1/Zeb2/Tbx2/Npnt/Nrp1/Cd44/Hoxa11/Adamts16/Gpc3/Areg/Mef2c/Foxf1/Tek/Cxcl12/Tcf21/Gli3/Ift57/Plxnd1/Gdf7/Lrp2/Cecr2/Mgp/Aplnr/Agtr1a/Tbx3/Rasip1/Tie1/Ednra/Prickle1/Pkd1/Nfatc4/Epha7/Ipmk/Dlc1/Ptch1/Dchs1/Osr1/Pkd2/Rab23/Fzd2/Dlg5/Fat4/Psen1/Bmp7/Hand2/Myc/Twist1/Eng	60
GO:0035107	appendage morphogenesis	BP	0.218	2.93e-15	7.05e-13	12.2	4.57e-13	Ihh/Sfrp2/Cacna1c/Lef1/Hoxd10/Hoxd11/Nog/Aff3/Pkdcc/Tbx2/Rnf165/Hoxa11/Gpc3/Hoxd9/Hoxa10/Cibar1/Osr2/Flvcr1/Gli3/Wnt9a/Cplane1/Enpp1/Tbx3/Dync2h1/Pcsk5/Hoxa9/Ptch1/Tmem231/Asph/Osr1/Ttbk2/Rab23/Psen1/Iqce/Bmp7/Lrp4/Hand2/Twist1	38
GO:0035108	limb morphogenesis	BP	0.218	2.93e-15	7.05e-13	12.2	4.57e-13	Ihh/Sfrp2/Cacna1c/Lef1/Hoxd10/Hoxd11/Nog/Aff3/Pkdcc/Tbx2/Rnf165/Hoxa11/Gpc3/Hoxd9/Hoxa10/Cibar1/Osr2/Flvcr1/Gli3/Wnt9a/Cplane1/Enpp1/Tbx3/Dync2h1/Pcsk5/Hoxa9/Ptch1/Tmem231/Asph/Osr1/Ttbk2/Rab23/Psen1/Iqce/Bmp7/Lrp4/Hand2/Twist1	38
GO:0006874	cellular calcium ion homeostasis	BP	0.138	3.21e-15	7.39e-13	12.1	4.79e-13	Kcnk3/Cacna1c/Kdr/Ryr1/Adra1a/Slc8a1/P2rx2/Pygm/Bok/Cacna2d1/Ednrb/Myo5a/Slc24a4/Inpp4b/Lpar4/Grin2b/Prkd1/Stc1/Cxcr3/Slc24a3/Cacna1e/Ptgfr/Ank2/Edn3/Slc8a3/Calca/Trpc6/Cdh5/Thy1/Pth1r/Nalf1/Coro1a/Grik2/Aplnr/Kctd17/Cd38/Agtr1a/Apoe/Ednra/Bdkrb2/Adcyap1r1/Htr2a/Xcl1/Pkd1/Selenon/Asph/Pkd2/Fyn/Xcr1/Ryr3/Slc25a23/Dlg4/Fzd2/Ptger3/Atp2b4/Gimap5/Gstm7/Atp1a2/Gimap3/Psen1/Sri/Cav1/Cacna1a/Cacnb4/F2r/Cd4/Kcnh1/Cd52/Ptger2	69
GO:0061138	morphogenesis of a branching epithelium	BP	0.191	3.36e-15	7.42e-13	12.1	4.81e-13	Ihh/Hgf/Sfrp2/Sema5a/Wnt6/Ar/Angpt1/Hhip/Mdk/Lef1/Hoxd11/Kdr/Nog/Igf1/Tbx2/Npnt/Nrp1/Cd44/Hoxa11/Adamts16/Gpc3/Areg/Foxf1/Tek/Cxcl12/Tcf21/Gli3/Plxnd1/Gdf7/Mgp/Agtr1a/Tbx3/Rasip1/Tie1/Ednra/Pkd1/Nfatc4/Ptch1/Dchs1/Dlg5/Fat4/Bmp7/Myc/Eng	44
GO:0007409	axonogenesis	BP	0.138	5.24e-15	1.11e-12	12	7.22e-13	Gap43/Epha8/Prtg/Efnb3/Ptprz1/Map2/Sema5a/Itga4/Lrrc4c/Pla2g10/Dcc/Plxnb1/Nog/Evl/Zeb2/Sema5b/Rnf165/Nrp1/Ptpro/Sema7a/Cdh2/Fn1/Dab1/Mef2c/Nptx1/Arhgef25/Cxcl12/Edn3/Gli3/Slitrk3/Ptprm/Plxnd1/Gdf7/Lrp2/Thy1/Ndn/Lama2/Epha3/Matn2/Nlgn3/Tsku/Apoe/Nfasc/Cdh11/Ednra/Sema3g/Nin/Rtn4rl1/Epha7/Neo1/Chodl/Ptch1/Unc5c/Syngap1/Brsk1/Psen1/Sema6a/Ulk2/Nrn1/Ntng1/Cacna1a/Bmp7/Lrp4/Bcl11b/Kif5a/Slit3/Draxin/Numbl	68
GO:0051924	regulation of calcium ion transport	BP	0.171	9.91e-15	2.03e-12	11.7	1.31e-12	Cacna1c/Jph4/Spink1/Igf1/Slc8a1/Nos3/Drd4/Cacna2d1/Myo5a/Icam1/Prkd1/Stc1/Cxcr3/Cxcl12/Ank2/Calca/Trpc6/Thy1/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Dysf/Bin1/Adcyap1r1/Tspan13/Stac2/Selenon/Arrb2/Asph/Pkd2/Fyn/Cd84/Rrad/Ptger3/Gnb5/Gimap5/Gstm7/Atp1a2/Gimap3/Sri/Pdgfrb/Cav1/Cacna1a/Usp2/Cacnb4/F2r/Cd4	49
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	BP	0.192	2.77e-14	5.48e-12	11.3	3.55e-12	Gpc6/Prtg/Pcdh18/Hmcn1/Sdk2/Mcam/Itga4/Lrrc4c/Ptprd/Nlgn1/Cdh2/Lrrc4b/Cdh6/Tenm3/Dab1/Cdh13/Pcdhgc3/Obsl1/Adgrl1/Cdh10/Slitrk3/Ptprm/Cdh5/Pcdh19/Pcdh12/Palld/Epha3/Itgal/Esam/Cdh11/Magi2/Sparcl1/Sele/Pecam1/Pcdh17/Dchs1/Fat3/Fat4/Pcdhb14/Ntng1/Cldn1	41
GO:0050673	epithelial cell proliferation	BP	0.137	3.4e-14	6.48e-12	11.2	4.2e-12	Gli1/Ihh/Hgf/Sfrp2/Sema5a/Ar/Mdk/Itga4/Cd109/Kdr/Agap2/Cyp7b1/Nog/Igf1/Tbx2/Gkn3/Fst/Ccnd2/Gpc3/Ednrb/Areg/Mef2c/Osr2/Prkd1/Cxcr3/Tek/Cdh13/Cxcl12/Has2/Vash1/Stxbp4/Ptprm/Calca/Ift57/Kit/Ppp1r16b/Aplnr/Jcad/Cdkn1c/Vegfc/Agtr1a/Apoe/Tie1/Ednra/Igf2/Dysf/Klf9/Twist2/Ptch1/Osr1/Aqp11/Akt3/Apln/Egfl7/Psen1/Ptn/Cav1/Igfbp4/Vash2/Cldn1/Wfdc1/Bcl11b/Myc/Twist1/Eng	65
GO:0060402	calcium ion transport into cytosol	BP	0.207	4.24e-14	7.73e-12	11.1	5.01e-12	Cacna1c/Ryr1/Adra1a/Slc8a1/Cacna2d1/Myo5a/Slc24a4/Grin2b/Prkd1/Cxcr3/Cacna1e/Ank2/Slc8a3/Calca/Thy1/Nalf1/Coro1a/Aplnr/Agtr1a/Ednra/Adcyap1r1/Htr2a/Xcl1/Selenon/Asph/Pkd2/Fyn/Xcr1/Ryr3/Gimap5/Gstm7/Gimap3/Sri/Cav1/Cacna1a/F2r/Cd4	37
GO:0031346	positive regulation of cell projection organization	BP	0.14	4.34e-14	7.73e-12	11.1	5.01e-12	Ptprz1/Hgf/Sema5a/Acsl6/Fez1/Mdk/Dcc/Plxnb1/Ptprd/Zeb2/Nlgn1/Ccdc88a/Lrrc7/Nrp1/Sema7a/Fn1/Tenm3/Prkd1/Serpine2/Cxcl12/Tbc1d24/Obsl1/Adamts1/Gprc5b/Plxnd1/Serpini1/Abi2/Kit/Epha3/Kctd17/Rp1/Eps8l1/Apoe/Magi2/Crocc/Caprin2/Ndnf/Nin/P3h1/Chodl/Bhlhb9/Ttbk2/Fyn/Dzip1/Dlg4/Cux2/Palm/Dpysl3/Cdc42ep5/Arsb/Def8/Ptn/Gpc2/Cpeb1/Atmin/Zmynd8/Enpp2/Ror1/Bmp7/Setx/Camk1/Numbl	62
GO:0010977	negative regulation of neuron projection development	BP	0.216	5.11e-14	8.83e-12	11.1	5.72e-12	Efnb3/Ptprz1/Map2/Sema5a/Sema5b/Nlgn1/Nrp1/Sema7a/Cspg4/Lrrk2/Ntm/Dab1/Thy1/Epha3/Minar1/Nlgn3/Tsku/Cd38/Apoe/Sema3g/Dennd5a/Rtn4rl1/Epha7/Neo1/Fat3/Xylt1/Dpysl3/Syngap1/Ngef/Psen1/Sema6a/Ulk2/Lrp4/Draxin/Zfp365	35
GO:0070588	calcium ion transmembrane transport	BP	0.163	5.78e-14	9.62e-12	11	6.23e-12	Nalcn/Cacna1c/Ryr1/Slc8a1/Drd4/Cacna2d1/Ednrb/Myo5a/Slc24a4/Grin2b/Prkd1/Cxcr3/Slc24a3/Cacna1e/Ank2/Slc8a3/Trpc6/Thy1/Nalf1/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Dysf/Bin1/Htr2a/Xcl1/Pkd1/Tspan13/Cacng7/Stac2/Selenon/Asph/Pkd2/Fyn/Xcr1/Ryr3/Rrad/Slc25a23/Ptger3/Atp2b4/Gnb5/Gstm7/Atp1a2/Sri/Cacna1a/Cacnb4/F2r	49
GO:0010959	regulation of metal ion transport	BP	0.139	5.91e-14	9.62e-12	11	6.23e-12	Cacna1c/Hecw2/Jph4/Spink1/Igf1/Slc8a1/Nos3/Scn4b/Drd4/Fxyd5/Cacna2d1/Myo5a/Icam1/Prkd1/Serpine2/Stc1/Cxcr3/Cxcl12/Ank2/Edn3/Plcb1/Calca/Trpc6/Thy1/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Dysf/Bin1/Adcyap1r1/Htr2a/Tspan13/Stac2/Kcnip3/Selenon/Arrb2/Asph/Osr1/Pkd2/Fhl1/Fyn/Cd84/Rrad/Akt3/Ptger3/Atp2b4/Gnb5/Gimap5/Gstm7/Atp1a2/Gimap3/Sri/Pdgfrb/Cav1/Cacna1a/Usp2/Cacnb4/F2r/Cd4/Mllt6	62
GO:0060401	cytosolic calcium ion transport	BP	0.194	7.68e-14	1.21e-11	10.9	7.86e-12	Cacna1c/Ryr1/Adra1a/Slc8a1/Cacna2d1/Myo5a/Slc24a4/Grin2b/Prkd1/Cxcr3/Cacna1e/Ank2/Slc8a3/Calca/Thy1/Nalf1/Coro1a/Aplnr/Agtr1a/Ednra/Adcyap1r1/Htr2a/Xcl1/Selenon/Asph/Pkd2/Fyn/Xcr1/Ryr3/Slc25a23/Ccn2/Gimap5/Gstm7/Gimap3/Sri/Cav1/Cacna1a/F2r/Cd4	39
GO:0051480	regulation of cytosolic calcium ion concentration	BP	0.144	1.56e-13	2.39e-11	10.6	1.55e-11	Kcnk3/Cacna1c/Kdr/Ryr1/Adra1a/Slc8a1/P2rx2/Bok/Cacna2d1/Ednrb/Myo5a/Slc24a4/Lpar4/Grin2b/Prkd1/Cxcr3/Cacna1e/Ptgfr/Ank2/Slc8a3/Calca/Trpc6/Thy1/Pth1r/Nalf1/Coro1a/Aplnr/Cd38/Agtr1a/Ednra/Bdkrb2/Adcyap1r1/Htr2a/Xcl1/Pkd1/Selenon/Asph/Pkd2/Fyn/Xcr1/Ryr3/Dlg4/Fzd2/Ptger3/Atp2b4/Gimap5/Gstm7/Atp1a2/Gimap3/Sri/Cav1/Cacna1a/F2r/Cd4/Kcnh1/Cd52/Ptger2	57
GO:0050678	regulation of epithelial cell proliferation	BP	0.141	3.64e-13	5.44e-11	10.3	3.53e-11	Gli1/Ihh/Sfrp2/Sema5a/Ar/Mdk/Itga4/Cd109/Kdr/Agap2/Cyp7b1/Nog/Igf1/Gkn3/Ccnd2/Gpc3/Ednrb/Mef2c/Osr2/Prkd1/Cxcr3/Tek/Cdh13/Cxcl12/Has2/Vash1/Stxbp4/Ptprm/Ift57/Ppp1r16b/Aplnr/Jcad/Cdkn1c/Vegfc/Agtr1a/Apoe/Tie1/Ednra/Igf2/Dysf/Klf9/Twist2/Ptch1/Osr1/Aqp11/Akt3/Apln/Egfl7/Ptn/Cav1/Vash2/Cldn1/Wfdc1/Bcl11b/Myc/Twist1/Eng	57
GO:0007159	leukocyte cell-cell adhesion	BP	0.144	4.13e-13	5.96e-11	10.2	3.86e-11	Ihh/Efnb3/Mdk/Lef1/Itga4/Cd83/Igf1/Chst2/Cd44/Ets1/Itgb7/Icam1/Podxl2/Cxcl12/Has2/Pik3r6/Gli3/Calca/Thy1/Tnfsf13b/Loxl3/Msn/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Sox12/Havcr2/H2-Ob/Sele/Pecam1/Igf2/Nckap1l/Xcl1/H2-Eb1/Stat5b/Pde5a/H2-Aa/Dlg5/Gimap5/St3gal4/Zap70/Gimap3/Il12rb1/Cav1/Il2rg/Spn/Bmp7/Il7r/Cd4/Rasal3/Jam2/Lax1	55
GO:0016358	dendrite development	BP	0.155	4.92e-13	6.81e-11	10.2	4.41e-11	Ptprz1/Map2/Hecw2/Ptprd/Mark1/Nlgn1/Tet1/Mpdz/Nrp1/Lrrk2/Dab1/Mef2c/Tbc1d24/Obsl1/Ppfia2/D16Ertd472e/Trpc6/Dock10/Abi2/Kif1a/Matn2/Nlgn3/Apoe/Caprin2/Prex2/Nfatc4/Sarm1/Bhlhb9/Fyn/Dlg4/Cux2/Palm/Dlg5/Fat3/Syngap1/Ngef/Bbs1/Psen1/Ptn/Cacna1a/Dact1/Zmynd8/Bmp7/Lrp4/Camk1/Nlgn2/Zfp365/Numbl/Rap2a	49
GO:1903039	positive regulation of leukocyte cell-cell adhesion	BP	0.169	1.05e-12	1.42e-10	9.85	9.17e-11	Ihh/Efnb3/Mdk/Lef1/Itga4/Cd83/Igf1/Chst2/Cd44/Ets1/Icam1/Has2/Pik3r6/Gli3/Thy1/Tnfsf13b/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Sox12/Havcr2/H2-Ob/Sele/Igf2/Nckap1l/Xcl1/H2-Eb1/Stat5b/H2-Aa/Gimap5/St3gal4/Zap70/Gimap3/Il12rb1/Cav1/Il2rg/Spn/Il7r/Cd4/Rasal3	42
GO:0030326	embryonic limb morphogenesis	BP	0.217	1.28e-12	1.64e-10	9.78	1.06e-10	Ihh/Sfrp2/Cacna1c/Lef1/Hoxd10/Hoxd11/Nog/Aff3/Tbx2/Hoxa11/Gpc3/Hoxd9/Hoxa10/Osr2/Flvcr1/Gli3/Wnt9a/Cplane1/Tbx3/Dync2h1/Hoxa9/Ptch1/Tmem231/Osr1/Ttbk2/Rab23/Psen1/Bmp7/Lrp4/Hand2/Twist1	31
GO:0035113	embryonic appendage morphogenesis	BP	0.217	1.28e-12	1.64e-10	9.78	1.06e-10	Ihh/Sfrp2/Cacna1c/Lef1/Hoxd10/Hoxd11/Nog/Aff3/Tbx2/Hoxa11/Gpc3/Hoxd9/Hoxa10/Osr2/Flvcr1/Gli3/Wnt9a/Cplane1/Tbx3/Dync2h1/Hoxa9/Ptch1/Tmem231/Osr1/Ttbk2/Rab23/Psen1/Bmp7/Lrp4/Hand2/Twist1	31
GO:0007204	positive regulation of cytosolic calcium ion concentration	BP	0.144	2.6e-12	3.21e-10	9.49	2.08e-10	Cacna1c/Kdr/Ryr1/Adra1a/Slc8a1/Cacna2d1/Ednrb/Myo5a/Slc24a4/Lpar4/Grin2b/Prkd1/Cxcr3/Cacna1e/Ptgfr/Ank2/Slc8a3/Calca/Trpc6/Thy1/Pth1r/Nalf1/Coro1a/Aplnr/Cd38/Agtr1a/Ednra/Bdkrb2/Adcyap1r1/Htr2a/Xcl1/Pkd1/Selenon/Asph/Pkd2/Fyn/Xcr1/Ryr3/Dlg4/Fzd2/Ptger3/Gimap5/Gstm7/Gimap3/Sri/Cav1/Cacna1a/F2r/Cd4/Cd52/Ptger2	51
GO:0007160	cell-matrix adhesion	BP	0.171	2.67e-12	3.21e-10	9.49	2.08e-10	Itga4/Kdr/Phldb2/Npnt/Nrp1/Fermt2/Col16a1/Itgb7/Fn1/Nid1/Jam3/Thsd1/Tek/Cdh13/Itga1/Col13a1/Frem1/Thy1/Postn/Ppm1f/Epha3/Itgal/Limch1/Arhgap6/Emilin1/Vegfc/Sned1/Hoxd3/Pecam1/Itga7/Pcsk5/Dlc1/Epdr1/Ccn2/Efemp2/Cd96/Itga8/Itgb4/Enpp2/Nid2	40
GO:0022409	positive regulation of cell-cell adhesion	BP	0.154	2.67e-12	3.21e-10	9.49	2.08e-10	Ihh/Efnb3/Mdk/Lef1/Itga4/Cd83/Igf1/Chst2/Cd44/Ets1/Icam1/Has2/Pik3r6/Gli3/Podxl/Thy1/Plpp3/Tnfsf13b/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Sox12/Havcr2/H2-Ob/Sele/Igf2/Nckap1l/Xcl1/H2-Eb1/Stat5b/Adam19/H2-Aa/Gimap5/St3gal4/Zap70/Gimap3/Il12rb1/Cav1/Il2rg/Spn/Bmp7/Il7r/Cd4/Rasal3	46
GO:0060485	mesenchyme development	BP	0.154	3.01e-12	3.53e-10	9.45	2.29e-10	Sfrp2/Sema5a/Mdk/Lef1/Wnt11/Itga4/Nog/Zeb2/Mark1/Tbx2/Sema5b/Phldb2/Nos3/Nrp1/Fermt2/Sema7a/Cdh2/Fn1/Ednrb/Mef2c/Foxf1/Erg/Has2/Tcf21/Edn3/Loxl3/Epha3/Aplnr/Tbx3/Ednra/Spred3/Heyl/Sema3g/Snai1/Kitl/Dchs1/Osr1/Il17rd/Dlg5/Sema6a/Bmp7/Hey2/Hand2/Myc/Twist1/Eng	46
GO:0003018	vascular process in circulatory system	BP	0.17	3.07e-12	3.53e-10	9.45	2.29e-10	Cacna1c/Angpt1/Kdr/Ddah1/Adra1a/Slc8a1/Nos3/Cbs/Npr3/Fermt2/Ednrb/Mmp2/Ptp4a3/Icam1/Wdr35/Abcg2/Akap12/Edn3/Itga1/Ptprm/Calca/Cdh5/Htr1b/Gucy1a1/Cd38/Agtr1a/Apoe/Kcnma1/Ednra/Bdkrb2/Htr2a/Pde5a/Cldn5/Ptger3/Apln/Atp1a2/Abcb1a/Cav1/Abcg3/F2r	40
GO:0010811	positive regulation of cell-substrate adhesion	BP	0.214	4.02e-12	4.54e-10	9.34	2.94e-10	Vit/Col26a1/Mdk/Kdr/Npnt/Nrp1/Fermt2/Spock2/Col16a1/Fn1/Foxf1/Nid1/Tek/Cdh13/Has2/Egflam/Thy1/Ppm1f/Smoc1/Emilin1/Vegfc/Ndnf/Pcsk5/Net1/Abi3bp/Efemp2/Ptn/Hacd1/Enpp2/Ccdc80	30
GO:0097485	neuron projection guidance	BP	0.162	4.59e-12	5.07e-10	9.29	3.29e-10	Gap43/Epha8/Prtg/Efnb3/Sema5a/Pla2g10/Dcc/Plxnb1/Nog/Evl/Sema5b/Rnf165/Nrp1/Ptpro/Sema7a/Mef2c/Dpysl4/Arhgef25/Cxcl12/Edn3/Gli3/Ptprm/Plxnd1/Gdf7/Lrp2/Lama2/Epha3/Matn2/Nfasc/Ednra/Sema3g/Rtn4rl1/Epha7/Neo1/Ptch1/Unc5c/Sema6a/Bmp7/Bcl11b/Kif5a/Slit3/Draxin	42
GO:0022407	regulation of cell-cell adhesion	BP	0.128	5.04e-12	5.46e-10	9.26	3.54e-10	Ihh/Efnb3/Mdk/Lef1/Itga4/Cd83/Igf1/Abat/Chst2/Cd44/Ets1/Tenm3/Icam1/Serpine2/Cxcl12/Has2/Pik3r6/Gli3/Podxl/Thy1/Plpp3/Tnfsf13b/Loxl3/Coro1a/Cd1d1/Ppm1f/Ccm2l/Itgal/H2-Ab1/Il27ra/Btla/Magi2/Sox12/Havcr2/H2-Ob/Sele/Igf2/Nckap1l/Xcl1/Epha7/H2-Eb1/Stat5b/Pde5a/Adam19/Ptger3/H2-Aa/Dlg5/Gimap5/St3gal4/Zap70/Gimap3/Il12rb1/Cav1/Il2rg/Spn/Bmp7/Il7r/Cd4/Rasal3/Lax1	60
GO:0043113	receptor clustering	BP	0.286	6.82e-12	7.25e-10	9.14	4.7e-10	Itga4/Nlgn1/Lrrc7/Cdh2/Itgb7/Grin2b/Slitrk3/Thy1/Glrb/Dlg2/Grik2/Itgal/Apoe/Magi2/Tnfaip6/Dlg4/Syngap1/Arhgef9/Ptn/Cacna1a/Lrp4/Nlgn2	22
GO:0032970	regulation of actin filament-based process	BP	0.133	9.66e-12	1.01e-09	9	6.53e-10	Kank4/Sema5a/Cacna1c/Mdk/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Hcls1/Fermt2/Tmod2/Wasf3/Mef2c/Pfn2/Icam1/Stc1/Jam3/Tek/Ank2/Abi2/Coro1a/Ppm1f/Epha3/Esam/Sh3bp1/Limch1/Arhgap6/Nox4/Arhgef15/Cnn2/Rhobtb3/Daam2/Pecam1/Tmeff2/Ppm1e/Scin/Bin1/Nckap1l/Carmil3/Dlc1/Myo1f/Arhgap28/Cacna1h/Fgr/Ptger3/Ccn2/Atp1a2/Cdc42ep5/Sri/Pdgfrb/Cav1/Plekhh2/Cyfip2/Plek	55
GO:0016055	Wnt signaling pathway	BP	0.129	1.01e-11	1.03e-09	8.99	6.68e-10	Gli1/Ndp/Sfrp2/Sema5a/Wnt6/Mdk/Lef1/Apcdd1/Wnt11/Pygo1/Nog/Zeb2/Mark1/Nkd1/Ptpro/Cd44/Fermt2/Arl6/Tert/Cdh2/Gpc3/Lrrk2/Ednrb/Rbms3/Tmem237/Gprc5b/Gli3/Peg12/Wnt9a/Plpp3/Cpe/Znrf3/Dkk3/Enpp1/Tsku/Apoe/Ednra/Daam2/Prickle1/Caprin2/Pkd1/Nfatc4/Tle1/Pkd2/Mgat3/Fzd2/Lats2/Psen1/Adgra2/Cav1/Dact1/Nkd2/Grb10/Tle2/Ror1/Lrp4/Myc/Draxin	58
GO:0198738	cell-cell signaling by wnt	BP	0.128	1.21e-11	1.19e-09	8.92	7.71e-10	Gli1/Ndp/Sfrp2/Sema5a/Wnt6/Mdk/Lef1/Apcdd1/Wnt11/Pygo1/Nog/Zeb2/Mark1/Nkd1/Ptpro/Cd44/Fermt2/Arl6/Tert/Cdh2/Gpc3/Lrrk2/Ednrb/Rbms3/Tmem237/Gprc5b/Gli3/Peg12/Wnt9a/Plpp3/Cpe/Znrf3/Dkk3/Enpp1/Tsku/Apoe/Ednra/Daam2/Prickle1/Caprin2/Pkd1/Nfatc4/Tle1/Pkd2/Mgat3/Fzd2/Lats2/Psen1/Adgra2/Cav1/Dact1/Nkd2/Grb10/Tle2/Ror1/Lrp4/Myc/Draxin	58
GO:0090287	regulation of cellular response to growth factor stimulus	BP	0.15	1.25e-11	1.21e-09	8.92	7.87e-10	Sfrp2/Angpt1/Hhip/Cd109/Kdr/Nog/Zeb2/Rnf165/Npnt/Fst/Gpc3/Ptp4a3/Tek/Zfp423/Cdh5/Lrp2/Pbld2/Zeb1/Jcad/Cdkn1c/Tsku/Emilin1/Vegfc/Tcf4/Spred3/Hipk2/Kcp/Tnfaip6/Neo1/Nrros/Zfyve9/Il17rd/Atp2b4/Apln/Fstl1/Lats2/Adgra2/Sema6a/Cav1/Cyfip2/Itga8/Grb10/Tmprss6/Nrep/Eng	45
GO:0050890	cognition	BP	0.139	1.51e-11	1.44e-09	8.84	9.3e-10	Stra6/Ptprz1/Cacna1c/Mdk/Cyp7b1/Jph4/Nog/Igf1/Aph1b/Aff2/Drd4/Tmod2/Ccnd2/Shc3/Mef2c/Chst10/B4galt2/Grin2b/Pde1b/Adcy3/Shank2/Cacna1e/Plcb1/Eif2ak4/Slc8a3/Abi2/Kit/Mme/Scn2a/Nlgn3/Apoe/Prrt1/Igf2/Htr2a/Nfatc4/Bhlhb9/Pde5a/Mgat3/Cux2/Ddhd2/St3gal4/Atp1a2/Syngap1/Brsk1/Psen1/Ptn/Itga8/Prkar1b/Lins1/Bche	50
GO:0007411	axon guidance	BP	0.159	1.59e-11	1.49e-09	8.83	9.68e-10	Gap43/Epha8/Prtg/Efnb3/Sema5a/Pla2g10/Dcc/Plxnb1/Nog/Evl/Sema5b/Rnf165/Nrp1/Ptpro/Sema7a/Mef2c/Arhgef25/Cxcl12/Edn3/Gli3/Ptprm/Plxnd1/Gdf7/Lrp2/Lama2/Epha3/Matn2/Nfasc/Ednra/Sema3g/Rtn4rl1/Epha7/Neo1/Ptch1/Unc5c/Sema6a/Bmp7/Bcl11b/Kif5a/Slit3/Draxin	41
GO:0042391	regulation of membrane potential	BP	0.126	1.66e-11	1.53e-09	8.82	9.91e-10	Kcnk3/Nalcn/Cacna1c/Grik1/Begain/Kcnd2/Kdr/Kcnd3/Nlgn1/Adra1a/Abat/Slc8a1/Celf4/Rims3/Scn4b/Stx1b/P2rx2/Drd4/Bok/Lrrk2/Scn1a/Cacna2d1/Slc24a4/Mef2c/Ano1/Grin2b/Tbc1d24/Ank2/Slc8a3/Glrb/Slc29a1/Scn2a/Gabra4/Grik2/Nlgn3/Kcnma1/Kcnc4/Bin1/Mpp2/Fhl1/Cacna1h/Dlg4/Cux2/Scn3a/Gimap5/Slc4a8/Gimap3/Psen1/Piezo2/Ptn/Cav1/Pid1/Cacna1a/Zmynd8/Cacnb4/Prkar1b/Kcnh1/Myc/Nlgn2	59
GO:0099173	postsynapse organization	BP	0.174	1.96e-11	1.77e-09	8.75	1.15e-09	Gap43/Ptprd/Nlgn1/Nrp1/Cdh2/Lrrk2/Lrrc4b/Nptx1/Grin2b/Shank2/Ppfia2/Slitrk3/Dock10/Glrb/Abi2/Kif1a/Nlgn3/Dgkb/Nptxr/Apoe/Magi2/Caprin2/Epha7/Bhlhb9/Lrfn2/Fyn/Dlg4/Cux2/Syngap1/Ngef/Arhgef9/Ptn/Zmynd8/Lrp4/Nlgn2/Zfp365	36
GO:0048762	mesenchymal cell differentiation	BP	0.161	3.21e-11	2.84e-09	8.55	1.84e-09	Sfrp2/Sema5a/Mdk/Lef1/Wnt11/Nog/Zeb2/Mark1/Sema5b/Phldb2/Nrp1/Fermt2/Sema7a/Cdh2/Fn1/Ednrb/Mef2c/Erg/Has2/Tcf21/Edn3/Loxl3/Epha3/Tbx3/Ednra/Spred3/Heyl/Sema3g/Snai1/Kitl/Osr1/Il17rd/Dlg5/Sema6a/Bmp7/Hey2/Hand2/Twist1/Eng	39
GO:1903037	regulation of leukocyte cell-cell adhesion	BP	0.14	3.24e-11	2.84e-09	8.55	1.84e-09	Ihh/Efnb3/Mdk/Lef1/Itga4/Cd83/Igf1/Chst2/Cd44/Ets1/Icam1/Cxcl12/Has2/Pik3r6/Gli3/Thy1/Tnfsf13b/Loxl3/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Sox12/Havcr2/H2-Ob/Sele/Igf2/Nckap1l/Xcl1/H2-Eb1/Stat5b/Pde5a/H2-Aa/Dlg5/Gimap5/St3gal4/Zap70/Gimap3/Il12rb1/Cav1/Il2rg/Spn/Il7r/Cd4/Rasal3/Lax1	48
GO:0050767	regulation of neurogenesis	BP	0.125	4.32e-11	3.68e-09	8.43	2.38e-09	Prtg/Efnb3/Ptprz1/Map2/Sema5a/Mdk/Kdr/Plxnb1/Ptprd/Nog/Igf1/Zeb2/Sema5b/Nrp1/Sema7a/Tert/Fn1/Dab1/Id4/Serpine2/Cxcl12/Tbc1d24/Obsl1/Gli3/Trpc6/Plxnd1/Lrp2/Thy1/Kit/Mme/Vegfc/Apoe/Heyl/Sema3g/Daam2/Caprin2/Bin1/Nin/Zcchc24/Nfatc4/Epha7/Chodl/Bhlhb9/Cux2/Syngap1/Psen1/Sema6a/Ulk2/Ptn/Enpp2/Bmp7/Hey2/Lrp4/Myc/Draxin/Zfp365/Numbl	57
GO:0007264	small GTPase mediated signal transduction	BP	0.128	4.66e-11	3.91e-09	8.41	2.53e-09	Igf1/Adra1a/Ccdc88a/Nrp1/Rasgrp3/Arl6/Cdh2/Garnl3/Dab1/Rasa3/Lpar4/Prkd1/Arhgef25/Cdh13/Arhgap25/Dock2/Rasgrp2/Sh2b2/Syde1/Dock10/Abi2/Sh3bp1/Eps8l1/Agtr1a/Apoe/Rasip1/Rhobtb3/Ednra/Pecam1/Adcyap1r1/Kitl/Arap3/Arrb1/Arl3/Heg1/Dlc1/Arhgap28/Net1/Arhgap31/Syngap1/Cdc42ep5/Arhgef9/Rab39b/Mapre2/Lat/Pdgfrb/Dennd4a/Sh2d3c/Iqsec3/Nradd/F2r/Sipa1/Rasal3/Rap2a/Plekhg5	55
GO:0022604	regulation of cell morphogenesis	BP	0.139	6.47e-11	5.34e-09	8.27	3.46e-09	Mdk/Kdr/Plxnb1/Ptprd/Epb41l3/Cpne5/Nrp1/Cd44/Fermt2/Fn1/Wasf3/Icam1/Tbc1d24/Has2/Obsl1/Myo9a/Plxnd1/Postn/Msn/Coro1a/Kit/Rhobtb3/Caprin2/Slc23a2/Itga7/Arap3/Cfap410/Parvb/Cacng7/Syne3/Dlc1/Bhlhb9/Net1/Fyn/Dlg4/Fgd1/Fgr/Cux2/Palm/Cdc42ep5/Plekho1/Arhgap15/Ptn/Ntng1/Enpp2/Fmnl3/Numbl	47
GO:0010810	regulation of cell-substrate adhesion	BP	0.163	7.3e-11	5.93e-09	8.23	3.84e-09	Ptprz1/Vit/Col26a1/Mdk/Kdr/Phldb2/Npnt/Nrp1/Fermt2/Spock2/Col16a1/Fn1/Foxf1/Nid1/Tek/Cdh13/Has2/Egflam/Thy1/Postn/Ppm1f/Smoc1/Epha3/Limch1/Arhgap6/Emilin1/Vegfc/Ndnf/Pcsk5/Dlc1/Net1/Abi3bp/Efemp2/Ptn/Hacd1/Enpp2/Ccdc80	37
GO:1902903	regulation of supramolecular fiber organization	BP	0.131	8.08e-11	6.48e-09	8.19	4.2e-09	Kank4/Map2/Sema5a/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Hcls1/Fermt2/Tmod2/Wasf3/Mef2c/Pfn2/Icam1/Cdh5/Abi2/Coro1a/Ppm1f/Esam/Rp1/Sh3bp1/Limch1/Arhgap6/Tubb4a/Emilin1/Apoe/Nox4/Arhgef15/Daam2/Pecam1/Tmeff2/Ppm1e/Scin/Dysf/Bin1/Nckap1l/Nin/Slain1/Carmil3/Dlc1/Arhgap28/Ttbk2/Ccn2/Efemp2/Cdc42ep5/Psen1/Cav1/Plekhh2/Cyfip2/Plek	51
GO:0048705	skeletal system morphogenesis	BP	0.153	8.79e-11	6.94e-09	8.16	4.5e-09	Col11a1/Ihh/Mmp16/Sfrp2/Hhip/Hoxd10/Hoxd11/Nog/Thbs3/Cbs/Hoxa11/Hoxd9/Mmp2/Mef2c/Hoxd8/Osr2/Hoxd4/Stc1/Has2/Flvcr1/Gli3/Col13a1/Frem1/Wnt9a/Zeb1/Enpp1/Hoxd3/Ltbp3/Pkd1/Hoxa9/Twist2/Osr1/Rab23/Fgr/Ccn2/Psen1/Pdgfrb/Bmp7/Myc/Twist1	40
GO:0003007	heart morphogenesis	BP	0.148	9.5e-11	7.4e-09	8.13	4.79e-09	Col11a1/Ihh/Sfrp2/Angpt1/Wnt11/Ryr1/Nog/Tbx2/Slc8a1/Nos3/Nrp1/Mef2c/Foxf1/Erg/Tek/Has2/Adamts1/Ift57/Plxnd1/Lrp2/Cpe/Ccm2l/Aplnr/Tbx3/Ednra/Heyl/Snai1/Myl3/Heg1/Dlc1/Ptch1/Dchs1/Pkd2/Fzd2/Fat4/Psen1/Bmp7/Hey2/Hand2/Slit3/Twist1/Eng	42
GO:0045765	regulation of angiogenesis	BP	0.143	9.71e-11	7.46e-09	8.13	4.83e-09	Cyp1b1/Hgf/Sfrp2/Sema5a/Hhip/Mdk/Kdr/Ddah1/Nos3/Nrp1/Ets1/Tert/Prkd1/Cxcr3/Tek/Pik3r6/Adamts1/Vash1/Ptprm/Plxnd1/Cdh5/Ppp1r16b/Aplnr/Minar1/Jcad/Emilin1/Ecscr/Vegfc/Agtr1a/Tcf4/Tie1/Igf2/Hipk2/Cldn5/Akt3/Atp2b4/Adgra2/Sema6a/Ptn/Vash2/Enpp2/Stab1/Fbln5/Eng	44
GO:0003012	muscle system process	BP	0.126	1.28e-10	9.7e-09	8.01	6.28e-09	Ar/Cacna1c/Sgcd/Col14a1/Ryr1/Igf1/Kcnd3/Tbx2/Npnt/Adra1a/Abat/Slc8a1/Nos3/Mybpc1/Scn4b/P2rx2/Tmod2/Scn1a/Cacna2d1/Ednrb/Mef2c/Stc1/Ank2/Edn3/Slc8a3/Calca/Tshz3/Gucy1a1/Kit/Cd38/Tbx3/Kcnma1/Ednra/Bin1/Bdkrb2/Htr2a/Myl3/Cmya5/Stac2/Selenon/Pde5a/Ryr3/Pi16/Calcrl/Cacna1h/Ptger3/Atp2b4/Ccn2/Atp1a2/Sri/Cav1/F2r/Hey2/Hand2	54
GO:0001505	regulation of neurotransmitter levels	BP	0.154	1.42e-10	1.06e-08	7.97	6.89e-09	Syn2/Maob/Slc6a2/Nlgn1/Adra1a/Abat/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Mef2c/Pfn2/Pde1b/Maoa/Edn3/Ppfia2/Syde1/Htr1b/Naalad2/Slc29a1/Cadps/Lin7a/Syt7/Prrt2/Kcnc4/Htr2a/Ncs1/Erc2/Atp1a2/Slc4a8/Brsk1/Stx2/Psen1/Nrn1/Cacna1a/Cacnb4/Kcnh1/Bche	39
GO:1901342	regulation of vasculature development	BP	0.141	1.49e-10	1.1e-08	7.96	7.11e-09	Cyp1b1/Hgf/Sfrp2/Sema5a/Hhip/Mdk/Kdr/Ddah1/Nos3/Nrp1/Ets1/Tert/Prkd1/Cxcr3/Tek/Pik3r6/Adamts1/Vash1/Ptprm/Plxnd1/Cdh5/Ppp1r16b/Aplnr/Minar1/Jcad/Emilin1/Ecscr/Vegfc/Agtr1a/Tcf4/Tie1/Igf2/Hipk2/Cldn5/Akt3/Atp2b4/Adgra2/Sema6a/Ptn/Vash2/Enpp2/Stab1/Fbln5/Eng	44
GO:0006936	muscle contraction	BP	0.14	2.04e-10	1.48e-08	7.83	9.61e-09	Cacna1c/Sgcd/Ryr1/Kcnd3/Tbx2/Npnt/Adra1a/Abat/Slc8a1/Mybpc1/Scn4b/P2rx2/Tmod2/Scn1a/Cacna2d1/Ednrb/Stc1/Ank2/Edn3/Slc8a3/Calca/Tshz3/Gucy1a1/Kit/Cd38/Tbx3/Kcnma1/Ednra/Bin1/Bdkrb2/Htr2a/Myl3/Stac2/Pde5a/Ryr3/Calcrl/Cacna1h/Ptger3/Atp2b4/Ccn2/Atp1a2/Sri/Cav1/F2r	44
GO:0060840	artery development	BP	0.216	2.15e-10	1.54e-08	7.81	9.98e-09	Apob/Stra6/Mdk/Wnt11/Nog/Tbx2/Nrp1/Kif7/Foxf1/Fkbp10/Gli3/Plxnd1/Lrp2/Prdm1/Aplnr/Enpp1/Apoe/Ednra/Prickle1/Akt3/Efemp2/Pdgfrb/Hey2/Hand2/Eng	25
GO:0018212	peptidyl-tyrosine modification	BP	0.138	2.32e-10	1.64e-08	7.78	1.07e-08	Ptprz1/Hgf/Sfrp2/Angpt1/Kdr/Spink1/Igf1/Ddr2/Pkdcc/Adra1a/Nrp1/Hcls1/Cd44/Cspg4/Areg/Icam1/Tpst1/Itk/Tek/Gprc5b/Thy1/Plpp3/Abi2/Kit/Epha3/Vegfc/Agtr1a/Nox4/Pecam1/Igf2/Kitl/Htr2a/Epha7/Arrb2/Fyn/Dlg4/Fgr/Zap70/Psen1/Pdgfrb/Il12rb1/Cav1/Enpp2/Cd4/Lrp4	45
GO:1903169	regulation of calcium ion transmembrane transport	BP	0.178	2.58e-10	1.78e-08	7.75	1.15e-08	Cacna1c/Slc8a1/Drd4/Cacna2d1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Dysf/Bin1/Tspan13/Stac2/Selenon/Asph/Pkd2/Fyn/Rrad/Ptger3/Gnb5/Gstm7/Atp1a2/Sri/Cacna1a/Cacnb4/F2r	31
GO:0006939	smooth muscle contraction	BP	0.214	2.61e-10	1.78e-08	7.75	1.15e-08	Cacna1c/Tbx2/Npnt/Adra1a/Abat/Slc8a1/P2rx2/Ednrb/Edn3/Calca/Tshz3/Gucy1a1/Kit/Cd38/Tbx3/Kcnma1/Ednra/Bdkrb2/Htr2a/Calcrl/Ptger3/Atp2b4/Atp1a2/Cav1/F2r	25
GO:0097553	calcium ion transmembrane import into cytosol	BP	0.187	2.91e-10	1.96e-08	7.71	1.27e-08	Cacna1c/Ryr1/Slc8a1/Myo5a/Slc24a4/Grin2b/Prkd1/Cxcr3/Cacna1e/Ank2/Slc8a3/Thy1/Nalf1/Coro1a/Aplnr/Agtr1a/Ednra/Htr2a/Xcl1/Selenon/Asph/Pkd2/Fyn/Xcr1/Ryr3/Gstm7/Sri/Cacna1a/F2r	29
GO:0050679	positive regulation of epithelial cell proliferation	BP	0.161	3.17e-10	2.11e-08	7.67	1.37e-08	Ihh/Sema5a/Ar/Mdk/Itga4/Kdr/Agap2/Cyp7b1/Nog/Igf1/Ccnd2/Osr2/Prkd1/Cdh13/Cxcl12/Has2/Stxbp4/Ppp1r16b/Aplnr/Jcad/Vegfc/Agtr1a/Igf2/Dysf/Twist2/Osr1/Akt3/Apln/Egfl7/Ptn/Cav1/Vash2/Cldn1/Myc/Twist1	35
GO:0009100	glycoprotein metabolic process	BP	0.136	3.83e-10	2.52e-08	7.6	1.63e-08	Col11a1/Ihh/St6gal2/Itm2a/Igf1/St8sia2/St8sia4/Gxylt2/Tet1/Man2a2/Uggt2/Spock2/Soat1/Chst10/Tmtc1/B3galnt1/Fut10/Egflam/Plcb1/Galnt16/St3gal2/Mamdc2/St6galnac4/Fbxo17/Eogt/Ggta1/Ndnf/Adamts7/St8sia6/Galntl6/Bgn/Poglut2/Dse/Mgat3/Pomt2/Aqp11/Large1/St6galnac6/B3gnt5/Xylt1/St3gal4/Psen1/Alg14/Galnt18/Dpy19l1	45
GO:1904062	regulation of cation transmembrane transport	BP	0.129	4.05e-10	2.63e-08	7.58	1.7e-08	Cacna1c/Hecw2/Nlgn1/Slc8a1/Scn4b/Drd4/Fxyd5/Cacna2d1/Myo5a/Mef2c/Prkd1/Cxcr3/Ank2/Edn3/Plcb1/Thy1/Coro1a/Aplnr/Nlgn3/Cracr2a/Agtr1a/Prrt1/Ednra/Dysf/Bin1/Tspan13/Cacng7/Stac2/Kcnip3/Selenon/Asph/Osr1/Pkd2/Fhl1/Fyn/Rrad/Dlg4/Ptger3/Atp2b4/Gnb5/Gstm7/Atp1a2/Sri/Cav1/Cacna1a/Cacnb4/F2r/Twist1/Nlgn2	49
GO:0045055	regulated exocytosis	BP	0.143	4.64e-10	2.98e-08	7.53	1.93e-08	Syn2/Cacna1c/Nlgn1/Syt13/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Foxf1/Pfn2/Mical1/Ppfia2/Syde1/Htr1b/Coro1a/Kit/Cadps/Syt7/Prrt2/Nckap1l/Htr2a/Myo1f/Ncs1/Erc2/Cd84/Cacna1h/Fgr/Slc4a8/Stx2/Psen1/Rab27a/Lat/Clnk/Nrn1/Cacna1a/Pld2/Cacnb4/Kcnh1/Plek	41
GO:0008589	regulation of smoothened signaling pathway	BP	0.234	4.83e-10	3.07e-08	7.51	1.99e-08	Gli1/Ihh/Hhip/Evc/Kif7/Arl6/Gpc3/Cibar1/Serpine2/Armc9/Gli3/Wnt9a/Rab34/Gpr161/Enpp1/Dync2h1/Ptch1/Ttbk2/Rab23/Dlg5/Glis2/Ift81	22
GO:0003205	cardiac chamber development	BP	0.165	5.53e-10	3.47e-08	7.46	2.25e-08	Col11a1/Stra6/Sfrp2/Wnt11/Nog/Tbx2/Nos3/Nrp1/Kif7/Mef2c/Foxf1/Tek/Adamts1/Ank2/Plxnd1/Lrp2/Cpe/Prdm1/Cplane1/Ccm2l/Aplnr/Tbx3/Ednra/Heyl/Myl3/Pcsk5/Heg1/Fzd2/Bmp7/Hey2/Hand2/Slit3/Eng	33
GO:0018108	peptidyl-tyrosine phosphorylation	BP	0.136	5.63e-10	3.49e-08	7.46	2.26e-08	Ptprz1/Hgf/Sfrp2/Angpt1/Kdr/Spink1/Igf1/Ddr2/Pkdcc/Adra1a/Nrp1/Hcls1/Cd44/Cspg4/Areg/Icam1/Itk/Tek/Gprc5b/Thy1/Plpp3/Abi2/Kit/Epha3/Vegfc/Agtr1a/Nox4/Pecam1/Igf2/Kitl/Htr2a/Epha7/Arrb2/Fyn/Dlg4/Fgr/Zap70/Psen1/Pdgfrb/Il12rb1/Cav1/Enpp2/Cd4/Lrp4	44
GO:0060070	canonical Wnt signaling pathway	BP	0.138	8.12e-10	4.99e-08	7.3	3.23e-08	Gli1/Sfrp2/Sema5a/Wnt6/Mdk/Lef1/Wnt11/Pygo1/Nog/Zeb2/Nkd1/Ptpro/Cdh2/Gpc3/Lrrk2/Ednrb/Rbms3/Gprc5b/Gli3/Peg12/Wnt9a/Plpp3/Znrf3/Dkk3/Apoe/Ednra/Daam2/Prickle1/Caprin2/Tle1/Mgat3/Fzd2/Lats2/Psen1/Adgra2/Cav1/Dact1/Nkd2/Tle2/Lrp4/Myc/Draxin	42
GO:0051145	smooth muscle cell differentiation	BP	0.25	8.46e-10	5.12e-08	7.29	3.31e-08	Tbx2/Npnt/Ednrb/Mef2c/Foxf1/Zeb1/Tshz3/Kit/Cth/Aplnr/Tbx3/Ednra/Nfatc4/Rbpms2/Efemp2/Sgcb/Pdgfrb/Itga8/Hey2/Eng	20
GO:0072073	kidney epithelium development	BP	0.184	8.51e-10	5.12e-08	7.29	3.31e-08	Wnt6/Hoxd11/Nog/Npnt/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Ednrb/Mef2c/Gdf11/Tcf21/Gli3/Tshz3/Agtr1a/Ednra/Heyl/Smad9/Epha7/Ptch1/Dchs1/Osr1/Aqp11/Fat4/Bmp7/Vcan/Myc	28
GO:0035296	regulation of tube diameter	BP	0.173	9.81e-10	5.69e-08	7.24	3.69e-08	Cacna1c/Kdr/Adra1a/Slc8a1/Nos3/Cbs/Npr3/Ednrb/Mmp2/Icam1/Wdr35/Edn3/Itga1/Ptprm/Calca/Htr1b/Gucy1a1/Cd38/Agtr1a/Apoe/Kcnma1/Ednra/Bdkrb2/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1/F2r	30
GO:0097746	blood vessel diameter maintenance	BP	0.173	9.81e-10	5.69e-08	7.24	3.69e-08	Cacna1c/Kdr/Adra1a/Slc8a1/Nos3/Cbs/Npr3/Ednrb/Mmp2/Icam1/Wdr35/Edn3/Itga1/Ptprm/Calca/Htr1b/Gucy1a1/Cd38/Agtr1a/Apoe/Kcnma1/Ednra/Bdkrb2/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1/F2r	30
GO:0050803	regulation of synapse structure or activity	BP	0.144	9.88e-10	5.69e-08	7.24	3.69e-08	Gpc6/Ptprd/St8sia2/Nlgn1/Ptpro/Rims3/Cdh2/Lrrk2/Lrrc4b/Mef2c/Nptx1/Grin2b/Shank2/Adgrl1/Ppfia2/Slitrk3/Abi2/Kif1a/Nlgn3/Dgkb/Apoe/Arhgef15/Magi2/Sparcl1/Caprin2/Nfatc4/Epha7/Bhlhb9/Lrfn2/Fyn/Cux2/Dlg5/Syngap1/Ngef/Ptn/Zmynd8/Lrp4/Camk1/Nlgn2	39
GO:0035150	regulation of tube size	BP	0.172	1.13e-09	6.45e-08	7.19	4.18e-08	Cacna1c/Kdr/Adra1a/Slc8a1/Nos3/Cbs/Npr3/Ednrb/Mmp2/Icam1/Wdr35/Edn3/Itga1/Ptprm/Calca/Htr1b/Gucy1a1/Cd38/Agtr1a/Apoe/Kcnma1/Ednra/Bdkrb2/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1/F2r	30
GO:0048562	embryonic organ morphogenesis	BP	0.132	1.35e-09	7.59e-08	7.12	4.92e-08	Gli1/Col11a1/Stra6/Ihh/Mmp16/Wnt11/Hoxd10/Hoxd11/Nog/Tbx2/Hoxa11/Hoxd9/Mef2c/Foxf1/Lrig3/Osr2/Hoxd4/Tshz1/Flvcr1/Tcf21/Gli3/Ift57/Wnt9a/Zeb1/Aplnr/Enpp1/Tbx3/Hoxd3/Ednra/Hipk2/Hoxa9/Twist2/Osr1/Pkd2/Fzd2/Psen1/Hipk1/Kcnq4/Itga8/Bmp7/Hand2/Myc/Twist1/Eng	44
GO:0050807	regulation of synapse organization	BP	0.144	1.44e-09	8.04e-08	7.09	5.21e-08	Gpc6/Ptprd/St8sia2/Nlgn1/Ptpro/Rims3/Cdh2/Lrrk2/Lrrc4b/Mef2c/Nptx1/Grin2b/Shank2/Adgrl1/Ppfia2/Slitrk3/Abi2/Kif1a/Nlgn3/Dgkb/Apoe/Arhgef15/Magi2/Sparcl1/Caprin2/Nfatc4/Epha7/Bhlhb9/Lrfn2/Fyn/Cux2/Dlg5/Ngef/Ptn/Zmynd8/Lrp4/Camk1/Nlgn2	38
GO:0048813	dendrite morphogenesis	BP	0.166	1.62e-09	8.98e-08	7.05	5.82e-08	Ptprz1/Hecw2/Ptprd/Nlgn1/Tet1/Nrp1/Lrrk2/Tbc1d24/Obsl1/Ppfia2/Trpc6/Dock10/Abi2/Kif1a/Nlgn3/Caprin2/Prex2/Nfatc4/Sarm1/Bhlhb9/Fyn/Dlg4/Cux2/Ngef/Ptn/Cacna1a/Dact1/Lrp4/Zfp365/Numbl/Rap2a	31
GO:1901888	regulation of cell junction assembly	BP	0.155	1.79e-09	9.78e-08	7.01	6.34e-08	Gpc6/Kdr/Ptprd/St8sia2/Nlgn1/Phldb2/Nrp1/Fermt2/Col16a1/Lrrc4b/Mef2c/Nptx1/Tek/Adgrl1/Slitrk3/Thy1/Ppm1f/Epha3/Aplnr/Nlgn3/Limch1/Arhgap6/Snai1/Epha7/Dlc1/Bhlhb9/Nphp1/Cldn5/Cux2/Dlg5/Cav1/Enpp2/Cldn1/Nlgn2	34
GO:0072006	nephron development	BP	0.178	1.83e-09	9.91e-08	7	6.42e-08	Wnt6/Angpt1/Hoxd11/Nog/Npnt/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Ednrb/Mef2c/Nid1/Enpep/Tek/Tcf21/Gli3/Agtr1a/Ednra/Heyl/Ptch1/Dchs1/Osr1/Aqp11/Fat4/Pdgfrb/Bmp7/Myc	28
GO:0007162	negative regulation of cell adhesion	BP	0.134	1.99e-09	1.06e-07	6.98	6.85e-08	Ihh/Cyp1b1/Ptprz1/Sema5a/Angpt1/Mdk/Lef1/Plxnb1/Phldb2/Abat/Cd44/Mmp2/Dab1/Serpine2/Jam3/Cdh13/Cxcl12/Gli3/Podxl/Plxnd1/Postn/Loxl3/Ppm1f/Ccm2l/H2-Ab1/Btla/Arhgap6/Havcr2/Nckap1l/Dlc1/Myo1f/Pde5a/Ptger3/H2-Aa/Dlg5/Gimap5/Gimap3/Sema6a/Spn/Enpp2/Jam2/Lax1	42
GO:0010631	epithelial cell migration	BP	0.134	1.99e-09	1.06e-07	6.98	6.85e-08	Cyp1b1/Sema5a/Angpt1/Kdr/Igf1/Evl/Zeb2/Nos3/Nrp1/Ets1/Mef2c/Pfn2/Ptp4a3/Prkd1/Stc1/Tek/Cdh13/Has2/Vash1/Ptprm/Calca/Plxnd1/Cdh5/Plpp3/Ppm1f/Kit/Jcad/Sh3bp1/Vegfc/Apoe/Daam2/Pecam1/Igf2/Hdac9/Akt3/Atp2b4/Fstl1/Arsb/Adgra2/Mapre2/Enpp2/Plekhg5	42
GO:0014848	urinary tract smooth muscle contraction	BP	0.643	2.15e-09	1.13e-07	6.95	7.33e-08	Cacna1c/Tbx2/P2rx2/Tshz3/Tbx3/Kcnma1/Htr2a/Ptger3/Atp2b4	9
GO:0001649	osteoblast differentiation	BP	0.153	2.27e-09	1.18e-07	6.93	7.68e-08	Gli1/Ihh/Sfrp2/Wnt11/Nog/Igf1/Ddr2/Npnt/Fermt2/Areg/Mef2c/Id3/Id4/Prkd1/Gli3/Glis1/Nell1/Pth1r/Gdf10/Smoc1/Enpp1/Vegfc/Igf2/Rorb/Tnfaip6/Twist2/Rassf2/Ptch1/Lrp3/Gabbr1/Bmp7/Hand2/Twist1/Zfp932	34
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.145	2.34e-09	1.21e-07	6.92	7.83e-08	Sfrp2/Cd109/Kdr/Nog/Zeb2/Rnf165/Npnt/Fst/Gpc3/Gdf11/Zfp423/Cdh5/Gdf7/Lrp2/Pbld2/Zeb1/Gdf10/Cdkn1c/Tsku/Emilin1/Magi2/Spred3/Hipk2/Kcp/Tnfaip6/Neo1/Nrros/Zfyve9/Il17rd/Fstl1/Lats2/Cav1/Itga8/Tmprss6/Bmp7/Nrep/Eng	37
GO:0090132	epithelium migration	BP	0.133	2.41e-09	1.23e-07	6.91	8e-08	Cyp1b1/Sema5a/Angpt1/Kdr/Igf1/Evl/Zeb2/Nos3/Nrp1/Ets1/Mef2c/Pfn2/Ptp4a3/Prkd1/Stc1/Tek/Cdh13/Has2/Vash1/Ptprm/Calca/Plxnd1/Cdh5/Plpp3/Ppm1f/Kit/Jcad/Sh3bp1/Vegfc/Apoe/Daam2/Pecam1/Igf2/Hdac9/Akt3/Atp2b4/Fstl1/Arsb/Adgra2/Mapre2/Enpp2/Plekhg5	42
GO:0099068	postsynapse assembly	BP	0.382	2.49e-09	1.26e-07	6.9	8.19e-08	Gap43/Ptprd/Nlgn1/Cdh2/Lrrc4b/Nptx1/Slitrk3/Nlgn3/Nptxr/Magi2/Arhgef9/Lrp4/Nlgn2	13
GO:0010522	regulation of calcium ion transport into cytosol	BP	0.207	2.53e-09	1.27e-07	6.9	8.25e-08	Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Calca/Thy1/Coro1a/Aplnr/Agtr1a/Ednra/Adcyap1r1/Selenon/Asph/Pkd2/Fyn/Gimap5/Gstm7/Gimap3/Sri/Cav1/F2r/Cd4	23
GO:0050870	positive regulation of T cell activation	BP	0.152	2.56e-09	1.27e-07	6.89	8.26e-08	Ihh/Efnb3/Mdk/Lef1/Cd83/Igf1/Pik3r6/Gli3/Thy1/Tnfsf13b/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Sox12/Havcr2/H2-Ob/Igf2/Nckap1l/Xcl1/H2-Eb1/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il12rb1/Cav1/Il2rg/Spn/Il7r/Cd4/Rasal3	34
GO:0048880	sensory system development	BP	0.119	2.6e-09	1.28e-07	6.89	8.31e-08	Ndp/Tmem132e/Stra6/Ihh/Cyp1b1/Sdk2/Cacna1c/Nhs/Kdr/Zeb2/Rcn1/Tub/Tbx2/Celf4/Nrp1/Lamc3/Arl6/Tenm3/Osr2/Obsl1/Bbs7/Sall2/Gdf11/Gli3/Ptprm/Thy1/Tgif2/Zeb1/Prdm1/Abi2/Smoc1/Rp1/Cdkn1c/Tsku/Arhgef15/Spred3/Col5a2/Pbx4/Lpcat1/Hipk2/Rorb/Twist2/Tmem231/Nphp1/Fat3/Pdgfrb/Ptn/Hipk1/Bmp7/Bcl11b/Twist1	51
GO:0030336	negative regulation of cell migration	BP	0.137	2.62e-09	1.28e-07	6.89	8.31e-08	Cyp1b1/Sfrp2/Wnt11/Nog/Evl/Phldb2/Tcaf1/Drd4/Mef2c/Pfn2/Stc1/Cxcl12/Vash1/Plcb1/Ptprm/Thy1/Gpr173/Robo4/Il27ra/Limch1/Emilin1/Apoe/Magi2/Cnn2/Tie1/Cd200/Tmeff2/Arap3/Tnfaip6/Dlc1/Cldn5/Atp2b4/Dlg5/Dpysl3/Egfl7/Ptn/Cygb/Zmynd8/Rap2a/Eng	40
GO:0048015	phosphatidylinositol-mediated signaling	BP	0.171	2.75e-09	1.33e-07	6.88	8.64e-08	Myo16/Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Car8/Hcls1/Npr3/Fn1/Serpine2/Tek/Plcb1/Ppp1r16b/Prr5l/Htr2a/Prex2/Plcb2/Ncs1/Fyn/Fgr/Pdgfrb/Pld2/Ror1/F2r/Kcnh1/Twist1/Irs1	29
GO:0072132	mesenchyme morphogenesis	BP	0.296	2.78e-09	1.34e-07	6.87	8.67e-08	Lef1/Wnt11/Nog/Tbx2/Nos3/Foxf1/Aplnr/Tbx3/Heyl/Snai1/Dchs1/Osr1/Bmp7/Myc/Twist1/Eng	16
GO:0043270	positive regulation of ion transport	BP	0.131	2.89e-09	1.36e-07	6.87	8.83e-08	Cacna1c/Grik1/Pla2g10/Tcaf1/Abat/Scn4b/Drd4/Cacna2d1/Myo5a/Grin2b/Stc1/Cxcr3/Cxcl12/Ank2/Edn3/Plcb1/Trpc6/Thy1/Aplnr/Nlgn3/Cracr2a/Agtr1a/Ednra/Adcyap1r1/Stac2/Arrb2/Asph/Pkd2/Fhl1/Akt3/Gimap5/Gstm7/Gimap3/Psen1/Abcb1a/Sri/Pdgfrb/Gabbr1/Cav1/Cacnb4/F2r/Cd4/Mllt6	43
GO:0032956	regulation of actin cytoskeleton organization	BP	0.126	2.9e-09	1.36e-07	6.87	8.83e-08	Kank4/Sema5a/Mdk/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Hcls1/Fermt2/Tmod2/Wasf3/Mef2c/Pfn2/Icam1/Jam3/Tek/Abi2/Coro1a/Ppm1f/Epha3/Esam/Sh3bp1/Limch1/Arhgap6/Nox4/Arhgef15/Rhobtb3/Daam2/Pecam1/Tmeff2/Ppm1e/Scin/Bin1/Nckap1l/Carmil3/Dlc1/Myo1f/Arhgap28/Fgr/Ccn2/Cdc42ep5/Pdgfrb/Plekhh2/Cyfip2/Plek	46
GO:0060348	bone development	BP	0.143	2.91e-09	1.36e-07	6.87	8.83e-08	Ihh/Mmp16/Sfrp2/Hoxd11/Kdr/Ryr1/Plxnb1/Igf1/Ddr2/Thbs3/Evc/Cbs/Hoxa11/Mef2c/Osr2/Stc1/Has2/Lrrc17/Gli3/Col13a1/Frem1/Fli1/Kit/Enpp1/Adamts7/Ltbp3/Tal1/Bgn/Smad9/P3h1/Dchs1/Rab23/Xylt1/Fat4/Twist1/Papss2/Fbln5	37
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	BP	0.205	3.04e-09	1.41e-07	6.85	9.16e-08	Prtg/Pcdh18/Hmcn1/Sdk2/Cdh2/Cdh6/Tenm3/Cdh13/Pcdhgc3/Obsl1/Cdh10/Ptprm/Cdh5/Pcdh19/Pcdh12/Palld/Esam/Cdh11/Pecam1/Dchs1/Fat3/Fat4/Pcdhb14	23
GO:0007015	actin filament organization	BP	0.116	3.57e-09	1.64e-07	6.78	1.07e-07	Kank4/Hmcn1/Sema5a/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Hcls1/Fermt2/Aif1l/Tmod2/Wasf3/Myo5a/Pfn2/Icam1/Mical1/Arhgap25/Abi2/Catip/Coro1a/Ppm1f/Esam/Sh3bp1/Limch1/Arhgap6/Nox4/Arhgef15/Rhobtb3/Daam2/Pecam1/Hip1/Tmeff2/Ppm1e/Scin/Bin1/Nckap1l/Efs/Carmil3/Arrb1/Dlc1/Myo1f/Arhgap28/Wipf1/Ccn2/Dpysl3/Cdc42ep5/Elmo2/Plekhh2/Cyfip2/Shroom1/Plek/Pstpip1	53
GO:0099504	synaptic vesicle cycle	BP	0.15	4.09e-09	1.87e-07	6.73	1.21e-07	Syn2/Nlgn1/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Cdh2/Lrrk2/Pfn2/Tbc1d24/Ppfia2/Syde1/Htr1b/Cadps/Nlgn3/Magi2/Syt7/Prrt2/Bin1/Htr2a/Pcdh17/Ncs1/Erc2/Slc4a8/Brsk1/Stx2/Psen1/Nrn1/Cacna1a/Cacnb4/Prkar1b/Kcnh1/Nlgn2	34
GO:0001654	eye development	BP	0.119	4.16e-09	1.87e-07	6.73	1.21e-07	Ndp/Stra6/Ihh/Cyp1b1/Sdk2/Cacna1c/Nhs/Kdr/Zeb2/Rcn1/Tub/Tbx2/Celf4/Nrp1/Lamc3/Arl6/Tenm3/Osr2/Obsl1/Bbs7/Sall2/Gdf11/Gli3/Ptprm/Thy1/Tgif2/Zeb1/Prdm1/Abi2/Smoc1/Rp1/Cdkn1c/Tsku/Arhgef15/Spred3/Col5a2/Pbx4/Lpcat1/Hipk2/Rorb/Twist2/Tmem231/Nphp1/Fat3/Pdgfrb/Ptn/Hipk1/Bmp7/Bcl11b/Twist1	50
GO:0048017	inositol lipid-mediated signaling	BP	0.168	4.16e-09	1.87e-07	6.73	1.21e-07	Myo16/Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Car8/Hcls1/Npr3/Fn1/Serpine2/Tek/Plcb1/Ppp1r16b/Prr5l/Htr2a/Prex2/Plcb2/Ncs1/Fyn/Fgr/Pdgfrb/Pld2/Ror1/F2r/Kcnh1/Twist1/Irs1	29
GO:0019932	second-messenger-mediated signaling	BP	0.133	4.3e-09	1.92e-07	6.72	1.24e-07	Sgcd/Kdr/Nr5a2/Spink1/Igf1/Slc8a1/Nos3/Cbs/Drd4/Gnai1/Lrrk2/Ednrb/Slc24a4/Gucy1a2/Cxcr3/Cdh13/Ptgfr/Adgrl1/Ank2/Edn3/Gucy1b1/Gucy1a1/Aplnr/Itgal/Agtr1a/Apoe/Ndnf/Adcyap1r1/Cap2/Cmya5/Nfatc4/Rasd2/Xcr1/Pde5a/Ptger3/Atp2b4/Zap70/Lat/Rcan3/Cd4/Tbc1d10c	41
GO:0042733	embryonic digit morphogenesis	BP	0.254	4.61e-09	2.04e-07	6.69	1.32e-07	Ihh/Sfrp2/Hoxd11/Nog/Tbx2/Hoxa11/Osr2/Flvcr1/Gli3/Cplane1/Tbx3/Tmem231/Osr1/Ttbk2/Rab23/Lrp4/Hand2/Twist1	18
GO:0007269	neurotransmitter secretion	BP	0.162	5.05e-09	2.2e-07	6.66	1.42e-07	Syn2/Nlgn1/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Syde1/Htr1b/Cadps/Lin7a/Syt7/Prrt2/Kcnc4/Htr2a/Ncs1/Erc2/Slc4a8/Brsk1/Stx2/Psen1/Nrn1/Cacna1a/Cacnb4/Kcnh1	30
GO:0099643	signal release from synapse	BP	0.162	5.05e-09	2.2e-07	6.66	1.42e-07	Syn2/Nlgn1/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Syde1/Htr1b/Cadps/Lin7a/Syt7/Prrt2/Kcnc4/Htr2a/Ncs1/Erc2/Slc4a8/Brsk1/Stx2/Psen1/Nrn1/Cacna1a/Cacnb4/Kcnh1	30
GO:0150063	visual system development	BP	0.118	5.27e-09	2.28e-07	6.64	1.47e-07	Ndp/Stra6/Ihh/Cyp1b1/Sdk2/Cacna1c/Nhs/Kdr/Zeb2/Rcn1/Tub/Tbx2/Celf4/Nrp1/Lamc3/Arl6/Tenm3/Osr2/Obsl1/Bbs7/Sall2/Gdf11/Gli3/Ptprm/Thy1/Tgif2/Zeb1/Prdm1/Abi2/Smoc1/Rp1/Cdkn1c/Tsku/Arhgef15/Spred3/Col5a2/Pbx4/Lpcat1/Hipk2/Rorb/Twist2/Tmem231/Nphp1/Fat3/Pdgfrb/Ptn/Hipk1/Bmp7/Bcl11b/Twist1	50
GO:0050863	regulation of T cell activation	BP	0.126	5.31e-09	2.28e-07	6.64	1.47e-07	Ihh/Efnb3/Mdk/Lef1/Cd83/Igf1/Cd44/Mapk8ip1/Pik3r6/Gli3/Thy1/Tnfsf13b/Loxl3/Zeb1/Prdm1/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Sox12/Havcr2/H2-Ob/Igf2/Nckap1l/Xcl1/H2-Eb1/Stat5b/Pde5a/H2-Aa/Dlg5/Gimap5/Zap70/Gimap3/Lat/Il12rb1/Cav1/Il2rg/Spn/Il7r/Cd4/Rasal3/Lax1	44
GO:0007043	cell-cell junction assembly	BP	0.174	6.02e-09	2.56e-07	6.59	1.66e-07	Wnt11/Epb41l3/Mpdz/Ptpro/Cdh2/Cdh6/Jam3/Cldn8/Cdh10/Cdh5/Abi2/Aplnr/Esam/Nfasc/Cdh11/Gjc1/Pecam1/Snai1/Heg1/Dchs1/Nphp1/Cldn5/Dlg5/Hipk1/Cav1/Pdcd6ip/Cldn1	27
GO:0051928	positive regulation of calcium ion transport	BP	0.179	6.11e-09	2.58e-07	6.59	1.67e-07	Cacna1c/Cacna2d1/Stc1/Cxcr3/Cxcl12/Ank2/Trpc6/Thy1/Aplnr/Cracr2a/Agtr1a/Ednra/Adcyap1r1/Stac2/Arrb2/Asph/Pkd2/Gimap5/Gstm7/Gimap3/Sri/Pdgfrb/Cav1/Cacnb4/F2r/Cd4	26
GO:0006836	neurotransmitter transport	BP	0.145	6.18e-09	2.59e-07	6.59	1.68e-07	Syn2/Slc6a2/Nlgn1/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Syde1/Htr1b/Slc6a15/Slc29a1/Cadps/Lin7a/Syt7/Prrt2/Kcnc4/Htr2a/Ncs1/Sv2c/Erc2/Atp1a2/Slc4a8/Brsk1/Stx2/Psen1/Nrn1/Cacna1a/Cacnb4/Kcnh1	35
GO:1903522	regulation of blood circulation	BP	0.139	6.76e-09	2.81e-07	6.55	1.82e-07	Cacna1c/Kcnd3/Adra1a/Slc8a1/Nos3/Scn4b/Cacna2d1/Ednrb/Mmp2/Icam1/Wdr35/Stc1/Hopx/Cacna1e/Ank2/Edn3/Calca/Cd38/Agtr1a/Gjc1/Ednra/Bin1/Htr2a/Myl3/Pde5a/Slc4a3/Cacna1h/Ptger3/Atp2b4/Ccn2/Apln/Atp1a2/Sri/Cav1/F2r/Hey2/Ptger2	37
GO:0051271	negative regulation of cellular component movement	BP	0.131	6.89e-09	2.84e-07	6.55	1.84e-07	Cyp1b1/Sfrp2/Wnt11/Nog/Evl/Phldb2/Tcaf1/Drd4/Mef2c/Pfn2/Stc1/Cxcl12/Vash1/Plcb1/Ptprm/Thy1/Gpr173/Robo4/Il27ra/Limch1/Emilin1/Apoe/Magi2/Cnn2/Tie1/Cd200/Tmeff2/Bin1/Arap3/Tnfaip6/Dlc1/Cldn5/Atp2b4/Dlg5/Dpysl3/Egfl7/Ptn/Cygb/Zmynd8/Rap2a/Eng	41
GO:0048844	artery morphogenesis	BP	0.235	7.02e-09	2.87e-07	6.54	1.86e-07	Apob/Stra6/Mdk/Wnt11/Nog/Tbx2/Nrp1/Foxf1/Fkbp10/Lrp2/Prdm1/Apoe/Ednra/Akt3/Efemp2/Pdgfrb/Hey2/Hand2/Eng	19
GO:0035249	synaptic transmission, glutamatergic	BP	0.197	7.38e-09	2.98e-07	6.53	1.93e-07	Grid1/Gria4/Grik1/Nlgn1/Aph1b/Cdh2/Lrrk2/Myo5a/Shc3/Mef2c/Grin2b/Serpine2/Shank2/Htr1b/Tshz3/Grik2/Nlgn3/Htr2a/Cacng7/Psen1/Cacna1a/Cacnb4/Nlgn2	23
GO:0045446	endothelial cell differentiation	BP	0.197	7.38e-09	2.98e-07	6.53	1.93e-07	Kdr/Ednrb/Icam1/Stc1/Plcb1/Cdh5/Zeb1/Msn/Ppp1r16b/Robo4/Tie1/Ednra/Pecam1/Col15a1/Heg1/Arhgef26/Cldn5/Fstl1/Akap11/Col18a1/Cldn1/Hey2/S1pr3	23
GO:0001936	regulation of endothelial cell proliferation	BP	0.168	7.63e-09	3.06e-07	6.51	1.98e-07	Sema5a/Mdk/Itga4/Kdr/Igf1/Mef2c/Prkd1/Cxcr3/Tek/Cdh13/Cxcl12/Vash1/Ptprm/Ppp1r16b/Aplnr/Jcad/Vegfc/Agtr1a/Apoe/Tie1/Igf2/Dysf/Akt3/Apln/Egfl7/Cav1/Vash2/Eng	28
GO:0008360	regulation of cell shape	BP	0.172	8.02e-09	3.19e-07	6.5	2.07e-07	Kdr/Plxnb1/Epb41l3/Fermt2/Fn1/Wasf3/Icam1/Plxnd1/Msn/Coro1a/Kit/Rhobtb3/Itga7/Arap3/Cfap410/Parvb/Syne3/Dlc1/Fyn/Fgd1/Fgr/Palm/Cdc42ep5/Plekho1/Arhgap15/Ptn/Fmnl3	27
GO:0045123	cellular extravasation	BP	0.232	8.72e-09	3.44e-07	6.46	2.23e-07	Mdk/Itga4/Chst2/Itgb7/Icam1/Podxl2/Jam3/Cxcl12/Itga1/Plcb1/Thy1/Itgal/Il27ra/Sele/Pecam1/Ptger3/St3gal4/Spn/Jam2	19
GO:2000146	negative regulation of cell motility	BP	0.131	9.26e-09	3.63e-07	6.44	2.35e-07	Cyp1b1/Sfrp2/Wnt11/Nog/Evl/Phldb2/Tcaf1/Drd4/Mef2c/Pfn2/Stc1/Cxcl12/Vash1/Plcb1/Ptprm/Thy1/Gpr173/Robo4/Il27ra/Limch1/Emilin1/Apoe/Magi2/Cnn2/Tie1/Cd200/Tmeff2/Arap3/Tnfaip6/Dlc1/Cldn5/Atp2b4/Dlg5/Dpysl3/Egfl7/Ptn/Cygb/Zmynd8/Rap2a/Eng	40
GO:0001885	endothelial cell development	BP	0.243	9.4e-09	3.66e-07	6.44	2.37e-07	Ednrb/Icam1/Stc1/Plcb1/Cdh5/Msn/Ppp1r16b/Robo4/Ednra/Pecam1/Col15a1/Heg1/Arhgef26/Cldn5/Akap11/Col18a1/Cldn1/S1pr3	18
GO:0099084	postsynaptic specialization organization	BP	0.318	9.74e-09	3.77e-07	6.42	2.44e-07	Gap43/Ptprd/Nlgn1/Cdh2/Lrrc4b/Nptx1/Shank2/Slitrk3/Nlgn3/Nptxr/Syngap1/Arhgef9/Zmynd8/Nlgn2	14
GO:0051216	cartilage development	BP	0.15	1.08e-08	4.13e-07	6.38	2.68e-07	Col11a1/Ihh/Sfrp2/Mdk/Hoxd11/Nog/Pkdcc/Thbs3/Cbs/Hoxa11/Mef2c/Osr2/Stc1/Gli3/Pth1r/Wnt9a/Zeb1/Mgp/Enpp1/Hoxd3/Adamts7/Snai1/Ltbp3/Pkd1/Bgn/Smad9/Osr1/Ccn2/Bbs1/Bmp7/Hand2/Mboat2	32
GO:0001823	mesonephros development	BP	0.2	1.12e-08	4.25e-07	6.37	2.76e-07	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Osr2/Gdf11/Tcf21/Gli3/Tshz3/Agtr1a/Smad9/Ptch1/Dchs1/Osr1/Fat4/Bmp7/Vcan/Myc	22
GO:0060079	excitatory postsynaptic potential	BP	0.217	1.15e-08	4.33e-07	6.36	2.81e-07	Grik1/Begain/Nlgn1/Celf4/Stx1b/Drd4/Lrrk2/Mef2c/Grin2b/Tbc1d24/Slc8a3/Slc29a1/Grik2/Nlgn3/Mpp2/Dlg4/Cux2/Zmynd8/Prkar1b/Nlgn2	20
GO:0030199	collagen fibril organization	BP	0.271	1.15e-08	4.33e-07	6.36	2.81e-07	Col11a1/Cyp1b1/Sfrp2/Col14a1/Ddr2/Fkbp10/Col13a1/Loxl3/Emilin1/Col5a2/Adamts7/P3h1/Dpt/Efemp2/Crtap/Lum	16
GO:0033674	positive regulation of kinase activity	BP	0.115	1.23e-08	4.59e-07	6.34	2.97e-07	Epha8/Angpt1/Kdr/Agap2/Igf1/Zeb2/Ddr2/Adra1a/Ccdc88a/Fermt2/Drd4/Ccnd2/Lrrk2/Areg/Dab1/Tek/Pik3r6/Gprc5b/Edn3/Calca/Flt3/Kit/Mmd/Epha3/Vegfc/Agtr1a/Nox4/Tie1/Kitl/Htr2a/Pkd1/Epha7/Rassf2/Arrb2/Pkd2/Pde5a/Dlg4/Fgr/Atp2b4/Acsl1/Psen1/Lat/Pdgfrb/Map4k2/C1qtnf9/Ror1/Fgd2/Cd4/Camk1/Irs1	50
GO:0001569	branching involved in blood vessel morphogenesis	BP	0.311	1.35e-08	5.01e-07	6.3	3.25e-07	Ihh/Sfrp2/Sema5a/Angpt1/Mdk/Lef1/Kdr/Nrp1/Tek/Cxcl12/Plxnd1/Ednra/Nfatc4/Eng	14
GO:0001935	endothelial cell proliferation	BP	0.158	1.54e-08	5.68e-07	6.25	3.68e-07	Sema5a/Mdk/Itga4/Kdr/Igf1/Mef2c/Prkd1/Cxcr3/Tek/Cdh13/Cxcl12/Vash1/Ptprm/Calca/Ppp1r16b/Aplnr/Jcad/Vegfc/Agtr1a/Apoe/Tie1/Igf2/Dysf/Akt3/Apln/Egfl7/Cav1/Vash2/Eng	29
GO:0099565	chemical synaptic transmission, postsynaptic	BP	0.204	1.67e-08	6.12e-07	6.21	3.97e-07	Grik1/Begain/Nlgn1/Abat/Celf4/Stx1b/Drd4/Lrrk2/Mef2c/Grin2b/Tbc1d24/Slc8a3/Slc29a1/Grik2/Nlgn3/Mpp2/Dlg4/Cux2/Zmynd8/Prkar1b/Nlgn2	21
GO:0003206	cardiac chamber morphogenesis	BP	0.171	1.69e-08	6.15e-07	6.21	3.99e-07	Col11a1/Sfrp2/Wnt11/Nog/Tbx2/Nos3/Nrp1/Mef2c/Foxf1/Tek/Adamts1/Lrp2/Cpe/Ccm2l/Aplnr/Tbx3/Ednra/Heyl/Myl3/Heg1/Fzd2/Bmp7/Hey2/Hand2/Slit3/Eng	26
GO:0006887	exocytosis	BP	0.116	1.82e-08	6.58e-07	6.18	4.26e-07	Syn2/Cacna1c/Nlgn1/Syt13/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Myo5a/Foxf1/Pfn2/Mical1/Exoc3l/Ppfia2/Syde1/Htr1b/Coro1a/Kit/Cadps/Lin7a/Syt7/Prrt2/Nckap1l/Htr2a/Myo1f/Ncs1/Erc2/Cd84/Cacna1h/Fgr/Septin4/Slc4a8/Stx2/Psen1/Rab27a/Lat/Clnk/Nrn1/Cacna1a/Pld2/Nkd2/Pdcd6ip/Cacnb4/Kcnh1/Plek/Prss12	48
GO:0110053	regulation of actin filament organization	BP	0.134	1.84e-08	6.58e-07	6.18	4.26e-07	Kank4/Sema5a/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Hcls1/Fermt2/Tmod2/Wasf3/Pfn2/Icam1/Abi2/Coro1a/Ppm1f/Esam/Sh3bp1/Limch1/Arhgap6/Nox4/Arhgef15/Daam2/Pecam1/Tmeff2/Ppm1e/Scin/Bin1/Nckap1l/Carmil3/Dlc1/Arhgap28/Ccn2/Cdc42ep5/Plekhh2/Cyfip2/Plek	37
GO:0060976	coronary vasculature development	BP	0.234	1.84e-08	6.58e-07	6.18	4.26e-07	Angpt1/Sgcd/Nrp1/Kif7/Gpc3/Plxnd1/Lrp2/Prdm1/Cplane1/Aplnr/Dync2h1/Prickle1/Pcsk5/Apln/Pdgfrb/Prokr1/Hey2/Hand2	18
GO:0099003	vesicle-mediated transport in synapse	BP	0.138	2.19e-08	7.75e-07	6.11	5.02e-07	Syn2/Nlgn1/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Cdh2/Lrrk2/Pfn2/Tbc1d24/Ppfia2/Syde1/Htr1b/Cadps/Nlgn3/Magi2/Syt7/Prrt2/Bin1/Htr2a/Pcdh17/Nsg1/Ncs1/Erc2/Slc4a8/Brsk1/Stx2/Psen1/Nrn1/Cacna1a/Cacnb4/Prkar1b/Kcnh1/Nlgn2	35
GO:0046631	alpha-beta T cell activation	BP	0.156	2.24e-08	7.88e-07	6.1	5.11e-07	Ihh/Lef1/Cd83/Wdfy4/Cd44/Itk/Mapk8ip1/Gli3/Dock2/Loxl3/Prdm1/Cd1d1/H2-Ab1/Btla/Cracr2a/Nckap1l/Xcl1/Satb1/Gimap5/Zap70/Gimap3/Il12rb1/Il2rg/Batf/Spn/Ly9/Bcl11b/Myc/Rasal3	29
GO:1901890	positive regulation of cell junction assembly	BP	0.185	2.34e-08	8.18e-07	6.09	5.3e-07	Kdr/Ptprd/St8sia2/Nlgn1/Nrp1/Fermt2/Col16a1/Lrrc4b/Tek/Adgrl1/Slitrk3/Thy1/Ppm1f/Nlgn3/Bhlhb9/Nphp1/Cldn5/Cux2/Dlg5/Cav1/Enpp2/Cldn1/Nlgn2	23
GO:0007265	Ras protein signal transduction	BP	0.123	2.74e-08	9.42e-07	6.03	6.1e-07	Igf1/Adra1a/Nrp1/Rasgrp3/Arl6/Cdh2/Rasa3/Lpar4/Prkd1/Arhgef25/Cdh13/Dock2/Rasgrp2/Sh2b2/Syde1/Abi2/Sh3bp1/Eps8l1/Agtr1a/Apoe/Rasip1/Ednra/Pecam1/Kitl/Arap3/Arrb1/Heg1/Dlc1/Net1/Syngap1/Cdc42ep5/Rab39b/Mapre2/Lat/Pdgfrb/Dennd4a/Iqsec3/Nradd/F2r/Rasal3/Rap2a/Plekhg5	42
GO:0030111	regulation of Wnt signaling pathway	BP	0.126	3.01e-08	1.02e-06	5.99	6.61e-07	Gli1/Sfrp2/Sema5a/Mdk/Lef1/Apcdd1/Wnt11/Nog/Zeb2/Nkd1/Ptpro/Tert/Cdh2/Gpc3/Lrrk2/Rbms3/Tmem237/Gprc5b/Gli3/Peg12/Plpp3/Znrf3/Dkk3/Tsku/Apoe/Daam2/Prickle1/Caprin2/Nfatc4/Tle1/Lats2/Psen1/Adgra2/Cav1/Dact1/Nkd2/Grb10/Tle2/Lrp4/Draxin	40
GO:0048706	embryonic skeletal system development	BP	0.171	3.1e-08	1.04e-06	5.98	6.75e-07	Col11a1/Ihh/Mmp16/Hoxd10/Hoxd11/Nog/Hoxa11/Hoxd9/Mef2c/Osr2/Hoxd4/Flvcr1/Gli3/Wnt9a/Zeb1/Hoxd3/Ednra/Pcsk5/Hoxa9/Twist2/Osr1/Xylt1/Bmp7/Hand2/Twist1	25
GO:0030178	negative regulation of Wnt signaling pathway	BP	0.162	3.11e-08	1.04e-06	5.98	6.75e-07	Gli1/Sfrp2/Mdk/Apcdd1/Wnt11/Nog/Nkd1/Ptpro/Cdh2/Gpc3/Rbms3/Gli3/Znrf3/Dkk3/Tsku/Apoe/Prickle1/Nfatc4/Tle1/Lats2/Cav1/Dact1/Nkd2/Grb10/Tle2/Lrp4/Draxin	27
GO:0001657	ureteric bud development	BP	0.196	3.38e-08	1.11e-06	5.96	7.17e-07	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gdf11/Tcf21/Gli3/Tshz3/Agtr1a/Smad9/Ptch1/Dchs1/Osr1/Fat4/Bmp7/Vcan/Myc	21
GO:0072163	mesonephric epithelium development	BP	0.196	3.38e-08	1.11e-06	5.96	7.17e-07	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gdf11/Tcf21/Gli3/Tshz3/Agtr1a/Smad9/Ptch1/Dchs1/Osr1/Fat4/Bmp7/Vcan/Myc	21
GO:0072164	mesonephric tubule development	BP	0.196	3.38e-08	1.11e-06	5.96	7.17e-07	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gdf11/Tcf21/Gli3/Tshz3/Agtr1a/Smad9/Ptch1/Dchs1/Osr1/Fat4/Bmp7/Vcan/Myc	21
GO:0043087	regulation of GTPase activity	BP	0.122	3.53e-08	1.15e-06	5.94	7.43e-07	Wnt11/Plxnb1/Rgs6/Fermt2/Rgs16/Rasgrp3/Garnl3/Lrrk2/Arhgap45/Rasa3/Icam1/Arhgap25/Rasgrp2/Myo9a/Plxnd1/Thy1/Dock10/Epha3/Sh3bp1/Arhgap6/Arhgef15/Rasip1/Pecam1/Bin1/Arap3/Xcl1/Arrb1/Arrb2/Arhgef26/Net1/Fgd1/Gnb5/Syngap1/Ngef/Mapre2/Arhgap15/Iqsec3/Gpsm1/F2r/Sipa1/Tbc1d10c/Rasal3	42
GO:0007229	integrin-mediated signaling pathway	BP	0.204	3.59e-08	1.16e-06	5.94	7.51e-07	Itga4/Nrp1/Fermt2/Sema7a/Itgb7/Fn1/Itga1/Thy1/Plpp3/Loxl3/Itgal/Itga7/Pcsk5/Fgr/Ccn2/Lat/Ptn/Itga8/Itgb4/Plek	20
GO:0072009	nephron epithelium development	BP	0.188	3.63e-08	1.17e-06	5.93	7.56e-07	Wnt6/Hoxd11/Nog/Npnt/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Ednrb/Mef2c/Tcf21/Gli3/Agtr1a/Ednra/Heyl/Ptch1/Dchs1/Osr1/Aqp11/Fat4/Myc	22
GO:0009581	detection of external stimulus	BP	0.175	3.7e-08	1.18e-06	5.93	7.62e-07	Col11a1/Sema5a/Igf1/Sema5b/Scn1a/Slc24a4/Ano1/Foxf1/Grin2b/Serpine2/Cxcl12/Calca/Kit/Grik2/Htr2a/Pkd1/Arrb1/Arrb2/Pkd2/Fyn/Piezo2/Pkdrej/Cacnb4/Myc	24
GO:0016079	synaptic vesicle exocytosis	BP	0.175	3.7e-08	1.18e-06	5.93	7.62e-07	Nlgn1/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Pfn2/Ppfia2/Syde1/Htr1b/Cadps/Syt7/Prrt2/Htr2a/Ncs1/Erc2/Slc4a8/Stx2/Psen1/Nrn1/Cacna1a/Cacnb4/Kcnh1	24
GO:0045667	regulation of osteoblast differentiation	BP	0.165	3.84e-08	1.21e-06	5.92	7.87e-07	Gli1/Sfrp2/Nog/Igf1/Ddr2/Npnt/Fermt2/Areg/Mef2c/Id3/Prkd1/Gli3/Nell1/Gdf10/Smoc1/Vegfc/Rorb/Tnfaip6/Twist2/Rassf2/Ptch1/Lrp3/Bmp7/Hand2/Twist1/Zfp932	26
GO:0003002	regionalization	BP	0.117	3.96e-08	1.24e-06	5.9	8.07e-07	Gli1/Sfrp2/Ar/Hhip/Lef1/Wnt11/Hoxd10/Hoxd11/Nog/Zeb2/Nrp1/Hoxa11/Dzip1l/Gpc3/Hoxd9/Hoxa10/Mef2c/Foxf1/Hoxd8/Hoxd4/Tshz1/Gdf11/Gli3/Ift57/Lrp2/Lfng/Gpr161/Tbx3/Dync2h1/Hoxd3/Ednra/Heyl/Snai1/Hipk2/Pcsk5/Hoxa9/Ptch1/Osr1/Nr2f1/Rab23/Ets2/Psen1/Hipk1/Hey2/Lrp4	45
GO:0070997	neuron death	BP	0.112	4.06e-08	1.27e-06	5.9	8.21e-07	Ptprz1/Angpt1/Mdk/Dcc/Kdr/Agap2/Igf1/Ddr2/St8sia2/Nrp1/Tert/Bok/Lrrk2/Mef2c/Dpysl4/Grin2b/Pcdhgc3/Tbc1d24/Itga1/Coro1a/Scn2a/Grik2/Il27ra/Rilpl1/Enpp1/Apoe/Kcnma1/Cd200/Slc23a2/Ndnf/Hipk2/Arrb1/Nfatc4/Epha7/Neo1/Kcnip3/Sarm1/Arrb2/Bhlhb9/Fyn/Nlrp1b/Syngap1/Psen1/Meak7/Nes/Cacna1a/Pcdhgc4/F2r/Draxin	49
GO:0060078	regulation of postsynaptic membrane potential	BP	0.186	4.26e-08	1.32e-06	5.88	8.57e-07	Grik1/Begain/Nlgn1/Abat/Celf4/Stx1b/Drd4/Lrrk2/Mef2c/Grin2b/Tbc1d24/Slc8a3/Slc29a1/Gabra4/Grik2/Nlgn3/Mpp2/Dlg4/Cux2/Zmynd8/Prkar1b/Nlgn2	22
GO:0001938	positive regulation of endothelial cell proliferation	BP	0.202	4.29e-08	1.33e-06	5.88	8.59e-07	Sema5a/Mdk/Itga4/Kdr/Igf1/Prkd1/Cdh13/Cxcl12/Ppp1r16b/Aplnr/Jcad/Vegfc/Agtr1a/Igf2/Dysf/Akt3/Apln/Egfl7/Cav1/Vash2	20
GO:1901215	negative regulation of neuron death	BP	0.134	4.38e-08	1.35e-06	5.87	8.72e-07	Ptprz1/Angpt1/Mdk/Kdr/Agap2/Igf1/Nrp1/Tert/Bok/Lrrk2/Mef2c/Pcdhgc3/Tbc1d24/Coro1a/Grik2/Il27ra/Apoe/Cd200/Slc23a2/Ndnf/Hipk2/Arrb1/Nfatc4/Neo1/Arrb2/Bhlhb9/Fyn/Syngap1/Psen1/Meak7/Nes/Cacna1a/Pcdhgc4/F2r/Draxin	35
GO:0043010	camera-type eye development	BP	0.118	4.62e-08	1.4e-06	5.85	9.1e-07	Ndp/Stra6/Ihh/Cyp1b1/Sdk2/Cacna1c/Nhs/Kdr/Zeb2/Rcn1/Tub/Tbx2/Celf4/Nrp1/Lamc3/Arl6/Tenm3/Osr2/Obsl1/Gdf11/Gli3/Ptprm/Thy1/Tgif2/Zeb1/Abi2/Rp1/Cdkn1c/Tsku/Arhgef15/Spred3/Lpcat1/Hipk2/Rorb/Twist2/Tmem231/Nphp1/Fat3/Pdgfrb/Ptn/Hipk1/Bmp7/Bcl11b/Twist1	44
GO:0030318	melanocyte differentiation	BP	0.379	4.72e-08	1.43e-06	5.85	9.25e-07	Zeb2/Adamts20/Ednrb/Myo5a/Mef2c/Edn3/Gli3/Kit/Enpp1/Kitl/Rab27a	11
GO:0070374	positive regulation of ERK1 and ERK2 cascade	BP	0.141	5.05e-08	1.52e-06	5.82	9.82e-07	Angpt1/Dcc/Kdr/Igf1/Ddr2/Npnt/Adra1a/Nrp1/Cd44/Fermt2/Sema7a/Icam1/Tek/Cxcl12/Akap12/Denn2b/Dnajc27/Apoe/Nox4/Havcr2/Ednra/Htr2a/Xcl1/Arrb1/Cavin3/Arrb2/Ccn2/Pdgfrb/Pde8a/F2r/Cd4/Hand2	32
GO:0010463	mesenchymal cell proliferation	BP	0.263	5.13e-08	1.53e-06	5.81	9.94e-07	Ihh/Wnt11/Kdr/Tbx2/Gpc3/Foxf1/Zeb1/Dchs1/Osr1/Fat4/Ptn/Bmp7/Hand2/Myc/Irs1	15
GO:0045216	cell-cell junction organization	BP	0.144	5.35e-08	1.59e-06	5.8	1.03e-06	Wnt11/Epb41l3/Mpdz/Ptpro/Fermt2/Cdh2/Cdh6/Jam3/Cldn8/Cdh10/Cdh5/Abi2/Aplnr/Esam/Nfasc/Cdh11/Gjc1/Pecam1/Snai1/Heg1/Dchs1/Svep1/Nphp1/Cldn5/Dlg5/Hipk1/Cav1/Pdcd6ip/Cldn1/F2r/Numbl	31
GO:0043542	endothelial cell migration	BP	0.14	5.6e-08	1.66e-06	5.78	1.07e-06	Cyp1b1/Sema5a/Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Mef2c/Ptp4a3/Prkd1/Stc1/Tek/Cdh13/Vash1/Ptprm/Calca/Plxnd1/Cdh5/Plpp3/Jcad/Sh3bp1/Vegfc/Apoe/Pecam1/Igf2/Hdac9/Akt3/Atp2b4/Fstl1/Adgra2/Plekhg5	32
GO:0048608	reproductive structure development	BP	0.107	5.93e-08	1.74e-06	5.76	1.13e-06	Ndp/Tex15/Stra6/Sfrp2/Ar/Angpt1/Lef1/Itga4/Kdr/Cyp7b1/Nog/Igf1/Slc8a1/Nos3/Fst/Cd44/Hoxa11/Il11ra1/Hoxa10/Mmp2/Icam1/Id4/Serpine2/Adamts1/Tcf21/Vash1/Gdf7/Lrp2/Syde1/Lfng/Prdm1/Pcdh12/Kit/Cdkn1c/Tbx3/Rhobtb3/Igf2/Snai1/Kitl/Pkd1/Arrb1/Tnfaip6/Hoxa9/Arrb2/Stat5b/Osr1/Pkd2/Abcb1a/Ptn/Vash2/Bmp7/Hey2	52
GO:0010563	negative regulation of phosphorus metabolic process	BP	0.109	6e-08	1.75e-06	5.76	1.13e-06	Hgf/Sfrp2/Angpt1/Cd109/Spink1/Nog/Igf1/Ddr2/Slc8a1/Ptpro/Lrrk2/Mical1/Mapk8ip1/Slc8a3/Pkia/Thy1/Plpp3/Ppm1f/Ppp1r16b/Enpp1/Cdkn1c/Emilin1/Ppef2/Prr5l/Apoe/Rasip1/Pecam1/Ppm1e/Nckap1l/Bdkrb2/Pkib/Lpcat1/Cmya5/Arrb1/Heg1/Rassf2/Arrb2/Lats2/Ppp1r26/Smpd1/Psen1/Cav1/Pid1/Grb10/Bmp7/Prkar1b/Twist1/Plek/Lax1/Eng	50
GO:0045936	negative regulation of phosphate metabolic process	BP	0.109	6e-08	1.75e-06	5.76	1.13e-06	Hgf/Sfrp2/Angpt1/Cd109/Spink1/Nog/Igf1/Ddr2/Slc8a1/Ptpro/Lrrk2/Mical1/Mapk8ip1/Slc8a3/Pkia/Thy1/Plpp3/Ppm1f/Ppp1r16b/Enpp1/Cdkn1c/Emilin1/Ppef2/Prr5l/Apoe/Rasip1/Pecam1/Ppm1e/Nckap1l/Bdkrb2/Pkib/Lpcat1/Cmya5/Arrb1/Heg1/Rassf2/Arrb2/Lats2/Ppp1r26/Smpd1/Psen1/Cav1/Pid1/Grb10/Bmp7/Prkar1b/Twist1/Plek/Lax1/Eng	50
GO:0003197	endocardial cushion development	BP	0.28	6.06e-08	1.75e-06	5.76	1.14e-06	Nog/Tbx2/Nos3/Foxf1/Erg/Epha3/Aplnr/Tbx3/Heyl/Snai1/Dchs1/Bmp7/Twist1/Eng	14
GO:0060021	roof of mouth development	BP	0.198	6.1e-08	1.76e-06	5.76	1.14e-06	Lef1/Wnt11/Pkdcc/Tbx2/Mef2c/Osr2/Tshz1/Bbs7/Gdf11/Tcf21/Gli3/Loxl3/Jag2/Cplane1/Tbx3/Snai1/Asph/Osr1/Fzd2/Hand2	20
GO:0001933	negative regulation of protein phosphorylation	BP	0.119	6.24e-08	1.78e-06	5.75	1.15e-06	Hgf/Sfrp2/Angpt1/Cd109/Spink1/Nog/Igf1/Slc8a1/Ptpro/Lrrk2/Mical1/Mapk8ip1/Slc8a3/Pkia/Thy1/Plpp3/Ppm1f/Enpp1/Cdkn1c/Emilin1/Ppef2/Prr5l/Apoe/Rasip1/Pecam1/Ppm1e/Bdkrb2/Pkib/Arrb1/Heg1/Rassf2/Arrb2/Lats2/Smpd1/Psen1/Cav1/Pid1/Bmp7/Prkar1b/Twist1/Lax1/Eng	42
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.115	6.27e-08	1.78e-06	5.75	1.15e-06	Sfrp2/Lef1/Cd109/Kdr/Nog/Zeb2/Rnf165/Npnt/Fst/Fermt2/Btbd11/Gpc3/Gdf11/Zfp423/Cdh5/Gdf7/Lrp2/Pbld2/Tgif2/Zeb1/Gdf10/Cdkn1c/Tsku/Emilin1/Magi2/Spred3/Ltbp3/Hipk2/Kcp/Tnfaip6/Smad9/Neo1/Nrros/Arrb2/Zfyve9/Cldn5/Il17rd/Fstl1/Lats2/Cav1/Itga8/Tmprss6/Bmp7/Nrep/Eng	45
GO:0010720	positive regulation of cell development	BP	0.116	6.31e-08	1.78e-06	5.75	1.15e-06	Ptprz1/Sema5a/Mdk/Hoxd11/Kdr/Plxnb1/Ptprd/Nog/Igf1/Zeb2/Nrp1/Fermt2/Sema7a/Hoxa11/Fn1/Serpine2/Cxcl12/Tbc1d24/Has2/Obsl1/Gli3/Plxnd1/Cdh5/Lrp2/Kit/Mme/Vegfc/Apoe/Caprin2/Bin1/Nin/Chodl/Bhlhb9/Net1/Pde5a/Cldn5/Cux2/Abcb1a/Ptn/Akap11/Enpp2/Myc/Zfp365/Numbl	44
GO:0099175	regulation of postsynapse organization	BP	0.189	6.6e-08	1.85e-06	5.73	1.2e-06	Ptprd/Nlgn1/Cdh2/Lrrk2/Lrrc4b/Nptx1/Grin2b/Ppfia2/Abi2/Kif1a/Nlgn3/Dgkb/Apoe/Caprin2/Epha7/Bhlhb9/Lrfn2/Fyn/Cux2/Ngef/Zmynd8	21
GO:1901214	regulation of neuron death	BP	0.115	6.76e-08	1.89e-06	5.72	1.22e-06	Ptprz1/Angpt1/Mdk/Dcc/Kdr/Agap2/Igf1/Ddr2/St8sia2/Nrp1/Tert/Bok/Lrrk2/Mef2c/Grin2b/Pcdhgc3/Tbc1d24/Itga1/Coro1a/Grik2/Il27ra/Rilpl1/Apoe/Kcnma1/Cd200/Slc23a2/Ndnf/Hipk2/Arrb1/Nfatc4/Epha7/Neo1/Kcnip3/Sarm1/Arrb2/Bhlhb9/Fyn/Syngap1/Psen1/Meak7/Nes/Cacna1a/Pcdhgc4/F2r/Draxin	45
GO:0050770	regulation of axonogenesis	BP	0.151	7.45e-08	2.07e-06	5.68	1.34e-06	Efnb3/Map2/Sema5a/Lrrc4c/Plxnb1/Zeb2/Sema5b/Nrp1/Sema7a/Cdh2/Fn1/Dab1/Cxcl12/Plxnd1/Thy1/Apoe/Sema3g/Nin/Epha7/Chodl/Syngap1/Brsk1/Psen1/Sema6a/Ulk2/Cacna1a/Lrp4/Draxin	28
GO:0061458	reproductive system development	BP	0.107	7.74e-08	2.14e-06	5.67	1.39e-06	Ndp/Tex15/Stra6/Sfrp2/Ar/Angpt1/Lef1/Itga4/Kdr/Cyp7b1/Nog/Igf1/Slc8a1/Nos3/Fst/Cd44/Hoxa11/Il11ra1/Hoxa10/Mmp2/Icam1/Id4/Serpine2/Adamts1/Tcf21/Vash1/Gdf7/Lrp2/Syde1/Lfng/Prdm1/Pcdh12/Kit/Cdkn1c/Tbx3/Rhobtb3/Igf2/Snai1/Kitl/Pkd1/Arrb1/Tnfaip6/Hoxa9/Arrb2/Stat5b/Osr1/Pkd2/Abcb1a/Ptn/Vash2/Bmp7/Hey2	52
GO:0003158	endothelium development	BP	0.173	9.05e-08	2.49e-06	5.6	1.61e-06	Kdr/Ednrb/Icam1/Stc1/Plcb1/Cdh5/Zeb1/Msn/Ppp1r16b/Robo4/Tie1/Ednra/Pecam1/Col15a1/Heg1/Arhgef26/Cldn5/Fstl1/Akap11/Col18a1/Cldn1/Hey2/S1pr3	23
GO:1990778	protein localization to cell periphery	BP	0.116	9.29e-08	2.54e-06	5.59	1.65e-06	Gpc6/Kcnb2/Ar/Pkdcc/Tub/Epb41l3/Ccdc88a/Stx1b/Arl6/Gnai1/Efr3b/Cdh2/Gga2/Abi3/Myo5a/Nptx1/Ank2/Rab34/Dlg2/Ttc7b/Epha3/Lin7a/Rilpl1/Nptxr/Nfasc/Magi2/Arl3/Nsg1/Cacng7/Stac2/Kcnip3/Ptch1/Dchs1/Tspan5/Dlg4/Palm/Atp2b4/Bbs1/Pid1/Nkd2/Golph3l/Rabep1/Rap2a	43
GO:0051056	regulation of small GTPase mediated signal transduction	BP	0.137	9.37e-08	2.55e-06	5.59	1.65e-06	Igf1/Adra1a/Nrp1/Cdh2/Garnl3/Rasa3/Lpar4/Arhgef25/Arhgap25/Dock2/Sh2b2/Syde1/Sh3bp1/Eps8l1/Apoe/Rasip1/Adcyap1r1/Kitl/Arap3/Arrb1/Heg1/Dlc1/Arhgap28/Net1/Syngap1/Mapre2/Pdgfrb/Dennd4a/Iqsec3/F2r/Sipa1/Rasal3	32
GO:0051966	regulation of synaptic transmission, glutamatergic	BP	0.212	9.44e-08	2.56e-06	5.59	1.66e-06	Gria4/Grik1/Nlgn1/Cdh2/Lrrk2/Myo5a/Mef2c/Grin2b/Serpine2/Shank2/Htr1b/Tshz3/Grik2/Nlgn3/Htr2a/Cacng7/Psen1/Nlgn2	18
GO:0090090	negative regulation of canonical Wnt signaling pathway	BP	0.172	1.04e-07	2.8e-06	5.55	1.82e-06	Gli1/Sfrp2/Mdk/Wnt11/Nog/Nkd1/Ptpro/Cdh2/Gpc3/Rbms3/Gli3/Znrf3/Dkk3/Apoe/Prickle1/Tle1/Lats2/Cav1/Dact1/Nkd2/Tle2/Lrp4/Draxin	23
GO:0042692	muscle cell differentiation	BP	0.11	1.05e-07	2.8e-06	5.55	1.82e-06	AW551984/Sgcd/Col14a1/Ryr1/Igf1/Tbx2/Npnt/Adra1a/Slc8a1/P2rx2/Tmod2/Cdh2/Ednrb/Mef2c/Foxf1/Cxcl12/Hopx/Ank2/Zeb1/Tshz3/Kit/Cth/Aplnr/Nox4/Tbx3/Ednra/Igf2/Dysf/Bin1/Hdac9/Nfatc4/Flnc/Neo1/Selenon/Arrb2/Pi16/Rbpms2/Efemp2/Sgcb/Plekho1/Pdgfrb/Itga8/Hacd1/Cacnb4/Hey2/Hand2/Camk1/Eng	48
GO:0061448	connective tissue development	BP	0.125	1.06e-07	2.82e-06	5.55	1.83e-06	Col11a1/Ihh/Sfrp2/Mdk/Hoxd11/Nog/Igf1/Pkdcc/Thbs3/Cbs/Hoxa11/Mef2c/Id4/Osr2/Stc1/Gli3/Gdf7/Pth1r/Wnt9a/Zeb1/Selenom/Mgp/Enpp1/Hoxd3/Adamts7/Snai1/Ltbp3/Pkd1/Bgn/Smad9/Osr1/Ccn2/Bbs1/Pdgfrb/Bmp7/Hand2/Mboat2	37
GO:0051208	sequestering of calcium ion	BP	0.177	1.07e-07	2.84e-06	5.55	1.84e-06	Ryr1/Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Htr2a/Xcl1/Selenon/Asph/Pkd2/Xcr1/Ryr3/Slc25a23/Gstm7/Psen1/Sri/F2r	22
GO:0043271	negative regulation of ion transport	BP	0.153	1.07e-07	2.84e-06	5.55	1.84e-06	Maob/Hecw2/Spink1/Abat/Nos3/Drd4/Myo5a/Icam1/Serpine2/Stc1/Calca/Htr1b/Dysf/Bin1/Htr2a/Osr1/Pkd2/Rrad/Ptger3/Gnb5/Gstm7/Atp1a2/Sri/Gabbr1/Cav1/Usp2/Twist1	27
GO:0051962	positive regulation of nervous system development	BP	0.117	1.08e-07	2.86e-06	5.54	1.85e-06	Ptprz1/Sema5a/Mdk/Kdr/Plxnb1/Ptprd/Nog/Igf1/Zeb2/St8sia2/Nlgn1/Nrp1/Sema7a/Fn1/Lrrc4b/Serpine2/Cxcl12/Tbc1d24/Obsl1/Adgrl1/Gli3/Slitrk3/Plxnd1/Lrp2/Kit/Mme/Nlgn3/Vegfc/Apoe/Caprin2/Bin1/Nin/Chodl/Bhlhb9/Cux2/Dlg5/Ptn/Enpp2/Myc/Nlgn2/Zfp365/Numbl	42
GO:0022898	regulation of transmembrane transporter activity	BP	0.127	1.2e-07	3.14e-06	5.5	2.03e-06	Hecw2/Nlgn1/Tcaf1/Scn4b/Drd4/Fxyd5/Cacna2d1/Myo5a/Mef2c/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Prrt1/Ednra/Dysf/Cacng7/Stac2/Selenon/Asph/Osr1/Pkd2/Fhl1/Rrad/Dlg4/Gnb5/Gstm7/Atp1a2/Abcb1a/Sri/Cav1/Cacna1a/Cacnb4/Twist1/Nlgn2	36
GO:0009612	response to mechanical stimulus	BP	0.152	1.21e-07	3.15e-06	5.5	2.04e-06	Col11a1/Stra6/Slc1a3/Mdk/Wnt11/Igf1/Slc8a1/Nos3/Scn1a/Mmp2/Grin2b/Serpine2/Cxcl12/Kit/Cnn2/Ednra/Htr2a/Pkd1/Pkd2/Fyn/Habp4/Atp1a2/Piezo2/Ptn/Pkdrej/Cav1/Myc	27
GO:0009101	glycoprotein biosynthetic process	BP	0.129	1.23e-07	3.2e-06	5.49	2.07e-06	St6gal2/Itm2a/Igf1/St8sia2/St8sia4/Gxylt2/Tet1/Uggt2/Soat1/Chst10/Tmtc1/B3galnt1/Fut10/Plcb1/Galnt16/St3gal2/St6galnac4/Eogt/Ggta1/St8sia6/Galntl6/Poglut2/Dse/Mgat3/Pomt2/Aqp11/Large1/St6galnac6/B3gnt5/Xylt1/St3gal4/Psen1/Alg14/Galnt18/Dpy19l1	35
GO:0006814	sodium ion transport	BP	0.133	1.27e-07	3.28e-06	5.48	2.12e-06	Nalcn/Hecw2/Slc6a2/Slc5a11/Slc13a5/Slc8a1/Nos3/Scn4b/Drd4/Fxyd5/Scn1a/Ednrb/Slc9a7/Slc24a4/Serpine2/Slc24a3/Plcb1/Slc8a3/Slc6a15/Maged2/Scn2a/Ednra/Slc9a5/Slc23a2/Osr1/Slc38a1/Pkd2/Akt3/Atp2b4/Scn3a/Atp1a2/Slc4a8/Mllt6	33
GO:0051926	negative regulation of calcium ion transport	BP	0.232	1.28e-07	3.28e-06	5.48	2.13e-06	Spink1/Nos3/Drd4/Icam1/Stc1/Calca/Dysf/Bin1/Pkd2/Rrad/Ptger3/Gnb5/Gstm7/Atp1a2/Sri/Usp2	16
GO:0006486	protein glycosylation	BP	0.147	1.32e-07	3.36e-06	5.47	2.18e-06	St6gal2/St8sia2/St8sia4/Gxylt2/Tet1/Uggt2/Tmtc1/B3galnt1/Fut10/Galnt16/St3gal2/St6galnac4/Eogt/Ggta1/St8sia6/Galntl6/Poglut2/Mgat3/Pomt2/Aqp11/Large1/St6galnac6/B3gnt5/St3gal4/Psen1/Alg14/Galnt18/Dpy19l1	28
GO:0043413	macromolecule glycosylation	BP	0.147	1.32e-07	3.36e-06	5.47	2.18e-06	St6gal2/St8sia2/St8sia4/Gxylt2/Tet1/Uggt2/Tmtc1/B3galnt1/Fut10/Galnt16/St3gal2/St6galnac4/Eogt/Ggta1/St8sia6/Galntl6/Poglut2/Mgat3/Pomt2/Aqp11/Large1/St6galnac6/B3gnt5/St3gal4/Psen1/Alg14/Galnt18/Dpy19l1	28
GO:0043524	negative regulation of neuron apoptotic process	BP	0.147	1.32e-07	3.36e-06	5.47	2.18e-06	Ptprz1/Angpt1/Mdk/Kdr/Agap2/Nrp1/Tert/Bok/Mef2c/Pcdhgc3/Coro1a/Grik2/Il27ra/Apoe/Ndnf/Hipk2/Arrb1/Nfatc4/Arrb2/Bhlhb9/Fyn/Syngap1/Psen1/Nes/Cacna1a/Pcdhgc4/F2r/Draxin	28
GO:0070371	ERK1 and ERK2 cascade	BP	0.117	1.37e-07	3.41e-06	5.47	2.21e-06	Angpt1/Dcc/Kdr/Igf1/Ddr2/Npnt/Adra1a/Nrp1/Cd44/Fermt2/Sema7a/Fn1/Icam1/Tek/Cxcl12/Akap12/Denn2b/Dnajc27/Emilin1/Apoe/Nox4/Havcr2/Ednra/Spred3/Htr2a/Xcl1/Arrb1/Cavin3/Epha7/Arrb2/Ccn2/Sema6a/Pdgfrb/Pde8a/Cav1/Grb10/F2r/Cd4/Hand2/Tbc1d10c/Myc	41
GO:0032409	regulation of transporter activity	BP	0.124	1.37e-07	3.41e-06	5.47	2.21e-06	Hecw2/Slc5a11/Nlgn1/Tcaf1/Scn4b/Drd4/Fxyd5/Cacna2d1/Myo5a/Mef2c/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Prrt1/Ednra/Dysf/Cacng7/Stac2/Selenon/Asph/Osr1/Pkd2/Fhl1/Rrad/Dlg4/Gnb5/Gstm7/Atp1a2/Abcb1a/Sri/Cav1/Cacna1a/Cacnb4/Twist1/Nlgn2	37
GO:0010976	positive regulation of neuron projection development	BP	0.138	1.37e-07	3.41e-06	5.47	2.21e-06	Ptprz1/Hgf/Acsl6/Fez1/Mdk/Dcc/Lrrc7/Tenm3/Prkd1/Serpine2/Adamts1/Gprc5b/Serpini1/Epha3/Apoe/Magi2/Caprin2/Ndnf/P3h1/Bhlhb9/Fyn/Cux2/Dpysl3/Arsb/Ptn/Gpc2/Cpeb1/Ror1/Bmp7/Setx/Camk1	31
GO:0050866	negative regulation of cell activation	BP	0.138	1.37e-07	3.41e-06	5.47	2.21e-06	Ihh/Mdk/Abat/Cd44/Foxf1/Serpine2/Gli3/Flt3/Loxl3/Prdm1/H2-Ab1/Btla/Emilin1/Apoe/Havcr2/Cd200/Nckap1l/Pde5a/Cd84/Fgr/Ptger3/H2-Aa/Dlg5/Gimap5/Gimap3/Clnk/Cygb/Nr1h3/Spn/Tbc1d10c/Lax1	31
GO:0009582	detection of abiotic stimulus	BP	0.169	1.38e-07	3.41e-06	5.47	2.21e-06	Col11a1/Sema5a/Igf1/Sema5b/Scn1a/Slc24a4/Ano1/Grin2b/Serpine2/Cxcl12/Calca/Kit/Grik2/Htr2a/Pkd1/Arrb1/Arrb2/Pkd2/Fyn/Piezo2/Pkdrej/Cacnb4/Myc	23
GO:0014065	phosphatidylinositol 3-kinase signaling	BP	0.169	1.38e-07	3.41e-06	5.47	2.21e-06	Myo16/Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Hcls1/Fn1/Serpine2/Tek/Ppp1r16b/Prr5l/Htr2a/Prex2/Fyn/Fgr/Pdgfrb/Pld2/Ror1/F2r/Twist1/Irs1	23
GO:0032412	regulation of ion transmembrane transporter activity	BP	0.128	1.48e-07	3.63e-06	5.44	2.35e-06	Hecw2/Nlgn1/Tcaf1/Scn4b/Drd4/Fxyd5/Cacna2d1/Myo5a/Mef2c/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Prrt1/Ednra/Dysf/Cacng7/Stac2/Selenon/Asph/Osr1/Pkd2/Fhl1/Rrad/Dlg4/Gnb5/Gstm7/Atp1a2/Abcb1a/Sri/Cav1/Cacna1a/Cacnb4/Nlgn2	35
GO:0003015	heart process	BP	0.132	1.54e-07	3.76e-06	5.43	2.43e-06	Cacna1c/Sgcd/Kcnd3/Adra1a/Slc8a1/Nos3/Scn4b/Scn1a/Cacna2d1/Ednrb/Stc1/Hopx/Cacna1e/Ank2/Edn3/Calca/Rps6ka2/Nox4/Gjc1/Ednra/Bin1/Myl3/Fyn/Pde5a/Slc4a3/Cacna1h/Atp2b4/Ccn2/Apln/Atp1a2/Sri/Cav1/Hey2	33
GO:0050771	negative regulation of axonogenesis	BP	0.229	1.58e-07	3.85e-06	5.42	2.49e-06	Efnb3/Map2/Sema5a/Sema5b/Nrp1/Sema7a/Dab1/Thy1/Sema3g/Epha7/Syngap1/Psen1/Sema6a/Ulk2/Lrp4/Draxin	16
GO:0002691	regulation of cellular extravasation	BP	0.283	1.59e-07	3.85e-06	5.42	2.49e-06	Mdk/Itga4/Chst2/Icam1/Jam3/Cxcl12/Plcb1/Thy1/Il27ra/Sele/Pecam1/Ptger3/St3gal4	13
GO:0035136	forelimb morphogenesis	BP	0.283	1.59e-07	3.85e-06	5.42	2.49e-06	Cacna1c/Hoxd10/Hoxd11/Rnf165/Hoxa11/Hoxd9/Osr2/Wnt9a/Enpp1/Tbx3/Hoxa9/Osr1/Twist1	13
GO:0071695	anatomical structure maturation	BP	0.123	1.62e-07	3.9e-06	5.41	2.53e-06	Epha8/Ihh/Pla2g10/Kdr/Ryr1/Plxnb1/Spink1/Igf1/Thbs3/Cspg4/Lrrk2/Ednrb/Mmp2/Myo5a/Slc24a4/Gdf11/Flvcr1/Plcb1/Calca/Rps6ka2/Cdh5/Pth1r/Dlg2/Enpp1/Cdkn1c/Nfasc/Kcnma1/Ednra/Adamts7/Tal1/Lhx6/Dchs1/Septin4/Xylt1/Fat4/Psen1/Cacna1a	37
GO:0003151	outflow tract morphogenesis	BP	0.205	1.65e-07	3.95e-06	5.4	2.56e-06	Sfrp2/Wnt11/Ryr1/Nog/Tbx2/Nrp1/Mef2c/Plxnd1/Lrp2/Tbx3/Ednra/Heyl/Fzd2/Bmp7/Hey2/Hand2/Twist1/Eng	18
GO:0050931	pigment cell differentiation	BP	0.308	1.69e-07	4.04e-06	5.39	2.61e-06	Zeb2/Adamts20/Ednrb/Myo5a/Mef2c/Ap1m1/Edn3/Gli3/Kit/Enpp1/Kitl/Rab27a	12
GO:0070372	regulation of ERK1 and ERK2 cascade	BP	0.12	1.71e-07	4.05e-06	5.39	2.62e-06	Angpt1/Dcc/Kdr/Igf1/Ddr2/Npnt/Adra1a/Nrp1/Cd44/Fermt2/Sema7a/Fn1/Icam1/Tek/Cxcl12/Akap12/Denn2b/Dnajc27/Emilin1/Apoe/Nox4/Havcr2/Ednra/Spred3/Htr2a/Xcl1/Arrb1/Cavin3/Epha7/Arrb2/Ccn2/Sema6a/Pdgfrb/Pde8a/Cav1/F2r/Cd4/Hand2/Tbc1d10c	39
GO:0071900	regulation of protein serine/threonine kinase activity	BP	0.116	1.73e-07	4.08e-06	5.39	2.64e-06	Sfrp2/Igf1/Zeb2/Slc8a1/Cbs/Fermt2/Drd4/Ccnd2/Lrrk2/Mapk8ip1/Pik3r6/Edn3/Slc8a3/Pkia/Thy1/Kit/Cdkn1c/Apoe/Nox4/Rasip1/Kitl/Htr2a/Pkib/Pkd1/Heg1/Pkd2/Pde5a/Atp2b4/Acsl1/Lats2/Smpd1/Psen1/Pdgfrb/Map4k2/Cav1/C1qtnf9/Fgd2/Bmp7/Prkar1b/Camk1/Lax1	41
GO:0007416	synapse assembly	BP	0.145	1.85e-07	4.35e-06	5.36	2.82e-06	Gpc6/Gap43/Sdk2/Plxnb1/Ptprd/St8sia2/Nlgn1/Cdh2/Lrrc4b/Mef2c/Nptx1/Shank2/Obsl1/Adgrl1/Slitrk3/Plxnd1/Nlgn3/Nptxr/Magi2/Pcdh17/Epha7/Bhlhb9/Cux2/Dlg5/Arhgef9/Cacna1a/Lrp4/Nlgn2	28
GO:0061326	renal tubule development	BP	0.185	1.95e-07	4.54e-06	5.34	2.94e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Mef2c/Tcf21/Gli3/Agtr1a/Heyl/Ptch1/Dchs1/Osr1/Pkd2/Aqp11/Fat4/Myc	20
GO:0050805	negative regulation of synaptic transmission	BP	0.202	1.98e-07	4.57e-06	5.34	2.96e-06	Grik1/Grid2ip/Celf4/Drd4/Gnai1/Lrrk2/Myo5a/Shank2/Htr1b/Grik2/Nlgn3/Sorcs2/Cd38/Prrt1/Htr2a/Pcdh17/Gabbr1/Bche	18
GO:0061333	renal tubule morphogenesis	BP	0.202	1.98e-07	4.57e-06	5.34	2.96e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Mef2c/Tcf21/Gli3/Agtr1a/Ptch1/Dchs1/Osr1/Pkd2/Fat4/Myc	18
GO:0045664	regulation of neuron differentiation	BP	0.133	2.06e-07	4.73e-06	5.32	3.07e-06	Sfrp2/Fez1/Nlgn1/Rgs6/Lrrk2/Ednrb/Dab1/Mef2c/Id4/Cxcl12/Gdf11/Gprc5b/Gli3/Eif2ak4/Trpc6/Gdf7/Tgif2/Zeb1/Mmd/Tcf4/Hoxd3/Heyl/Zc4h2/Bin1/Nin/Ptger3/Cav1/Bend6/Bmp7/Hey2/Nrep/Bcl11b	32
GO:0031644	regulation of nervous system process	BP	0.144	2.06e-07	4.73e-06	5.32	3.07e-06	Hgf/Begain/Igf1/Nlgn1/Abat/Nos3/Celf4/Stx1b/Drd4/Wasf3/Lrrk2/Ednrb/Nptx1/Grin2b/Tbc1d24/Slc8a3/Calca/Nlgn3/Nptxr/Kcnc4/Dlg4/Cux2/Tppp/Zmynd8/F2r/Prkar1b/Nlgn2/Jam2	28
GO:0045766	positive regulation of angiogenesis	BP	0.148	2.15e-07	4.87e-06	5.31	3.16e-06	Cyp1b1/Hgf/Sfrp2/Sema5a/Mdk/Kdr/Ddah1/Nos3/Nrp1/Ets1/Tert/Prkd1/Cxcr3/Tek/Pik3r6/Cdh5/Aplnr/Jcad/Emilin1/Vegfc/Agtr1a/Tie1/Igf2/Hipk2/Akt3/Vash2/Eng	27
GO:1904018	positive regulation of vasculature development	BP	0.148	2.15e-07	4.87e-06	5.31	3.16e-06	Cyp1b1/Hgf/Sfrp2/Sema5a/Mdk/Kdr/Ddah1/Nos3/Nrp1/Ets1/Tert/Prkd1/Cxcr3/Tek/Pik3r6/Cdh5/Aplnr/Jcad/Emilin1/Vegfc/Agtr1a/Tie1/Igf2/Hipk2/Akt3/Vash2/Eng	27
GO:0001755	neural crest cell migration	BP	0.238	2.17e-07	4.87e-06	5.31	3.16e-06	Sema5a/Zeb2/Sema5b/Nrp1/Sema7a/Fn1/Ednrb/Edn3/Ednra/Sema3g/Kitl/Sema6a/Bmp7/Hand2/Twist1	15
GO:0010721	negative regulation of cell development	BP	0.141	2.17e-07	4.87e-06	5.31	3.16e-06	Prtg/Efnb3/Map2/Sema5a/Nog/Igf1/Sema5b/Nrp1/Sema7a/Tert/Ednrb/Dab1/Id4/Trpc6/Thy1/Postn/Sema3g/Daam2/Nfatc4/Epha7/Syngap1/Psen1/Sema6a/Ulk2/Ptn/Bmp7/Lrp4/S1pr3/Draxin	29
GO:0071805	potassium ion transmembrane transport	BP	0.141	2.17e-07	4.87e-06	5.31	3.16e-06	Kcnk3/Kcnb2/Nalcn/Slc1a3/Kcnj3/Kcna6/Kcnd2/Kcnd3/Slc12a8/Kcnq5/Slc9a7/Slc24a4/Slc24a3/Ank2/Edn3/Kcnma1/Slc9a5/Kcnc4/Bin1/Kcnip3/Slc12a4/Pkd2/Fhl1/Kcng4/Ptger3/Atp1a2/Cav1/Kcnq4/Kcnh1	29
GO:0042476	odontogenesis	BP	0.171	2.21e-07	4.94e-06	5.31	3.2e-06	Wnt6/Lef1/Apcdd1/Fst/Edaradd/Myo5a/Slc24a4/Id3/Osr2/Gli3/Jag2/Enpp1/Tnfrsf11b/Ednra/Osr1/Hacd1/Edar/Bmp7/Lrp4/Hand2/Bcl11b/Ank	22
GO:0042310	vasoconstriction	BP	0.183	2.28e-07	5.05e-06	5.3	3.27e-06	Cacna1c/Adra1a/Slc8a1/Ednrb/Mmp2/Icam1/Wdr35/Edn3/Htr1b/Cd38/Agtr1a/Ednra/Bdkrb2/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1/F2r	20
GO:0048704	embryonic skeletal system morphogenesis	BP	0.183	2.28e-07	5.05e-06	5.3	3.27e-06	Col11a1/Mmp16/Hoxd10/Hoxd11/Nog/Hoxa11/Hoxd9/Mef2c/Osr2/Hoxd4/Flvcr1/Gli3/Wnt9a/Zeb1/Hoxd3/Hoxa9/Twist2/Osr1/Bmp7/Twist1	20
GO:0003231	cardiac ventricle development	BP	0.159	2.47e-07	5.47e-06	5.26	3.54e-06	Col11a1/Stra6/Sfrp2/Wnt11/Nog/Nos3/Mef2c/Foxf1/Lrp2/Cpe/Prdm1/Cplane1/Ccm2l/Aplnr/Tbx3/Ednra/Heyl/Myl3/Heg1/Fzd2/Hey2/Hand2/Slit3/Eng	24
GO:0003279	cardiac septum development	BP	0.169	2.54e-07	5.56e-06	5.25	3.6e-06	Stra6/Wnt11/Nog/Tbx2/Nos3/Nrp1/Kif7/Ank2/Plxnd1/Lrp2/Prdm1/Cplane1/Aplnr/Tbx3/Heyl/Pcsk5/Heg1/Fzd2/Bmp7/Hey2/Slit3/Eng	22
GO:0060996	dendritic spine development	BP	0.169	2.54e-07	5.56e-06	5.25	3.6e-06	Nlgn1/Lrrk2/Mef2c/Ppfia2/D16Ertd472e/Dock10/Abi2/Kif1a/Nlgn3/Apoe/Caprin2/Bhlhb9/Dlg4/Cux2/Palm/Dlg5/Ngef/Psen1/Zmynd8/Camk1/Nlgn2/Zfp365	22
GO:0060537	muscle tissue development	BP	0.103	2.59e-07	5.66e-06	5.25	3.67e-06	Gli1/Col11a1/Stra6/Ihh/AW551984/Angpt1/Lef1/Sgcd/Hoxd10/Col14a1/Ryr1/Nog/Igf1/Tbx2/Adra1a/Slc8a1/P2rx2/Hoxd9/Mef2c/Tcf21/Lrp2/Tshz3/Ccm2l/Nox4/Tbx3/Gjc1/Ednra/Heyl/Igf2/Dysf/Myl3/Hdac9/Heg1/Selenon/Arrb2/Osr1/Pi16/Efemp2/Sgcb/Hlf/Pdgfrb/Zfp689/Cav1/Itga8/Usp2/Bmp7/Hey2/Hand2/Myc/Twist1/Eng	51
GO:1903305	regulation of regulated secretory pathway	BP	0.146	2.69e-07	5.86e-06	5.23	3.8e-06	Nlgn1/Syt13/Adra1a/Rims3/P2rx2/Drd4/Lrrk2/Foxf1/Pfn2/Mical1/Ppfia2/Htr1b/Cadps/Syt7/Nckap1l/Htr2a/Ncs1/Cd84/Cacna1h/Fgr/Slc4a8/Rab27a/Nrn1/Cacna1a/Pld2/Cacnb4/Kcnh1	27
GO:0090596	sensory organ morphogenesis	BP	0.119	2.73e-07	5.91e-06	5.23	3.83e-06	Col11a1/Stra6/Ihh/Sdk2/Kdr/Nog/Tbx2/Arl6/Tenm3/Lrig3/Osr2/Tshz1/Obsl1/Gdf11/Gli3/Ptprm/Thy1/Zeb1/Prdm1/Abi2/Rp1/Enpp1/Tsku/Tbx3/Ednra/Col5a2/Hipk2/Rorb/Osr1/Fzd2/Fat3/Ptn/Hipk1/Kcnq4/Itga8/Bmp7/Myc/Twist1	38
GO:0050768	negative regulation of neurogenesis	BP	0.153	2.83e-07	6.1e-06	5.21	3.95e-06	Prtg/Efnb3/Map2/Sema5a/Nog/Sema5b/Nrp1/Sema7a/Tert/Dab1/Id4/Trpc6/Thy1/Sema3g/Daam2/Nfatc4/Epha7/Syngap1/Psen1/Sema6a/Ulk2/Ptn/Bmp7/Lrp4/Draxin	25
GO:0008016	regulation of heart contraction	BP	0.142	2.85e-07	6.13e-06	5.21	3.97e-06	Cacna1c/Kcnd3/Adra1a/Slc8a1/Nos3/Scn4b/Cacna2d1/Ednrb/Stc1/Hopx/Cacna1e/Ank2/Edn3/Calca/Gjc1/Ednra/Bin1/Myl3/Pde5a/Slc4a3/Cacna1h/Atp2b4/Ccn2/Apln/Atp1a2/Sri/Cav1/Hey2	28
GO:0072577	endothelial cell apoptotic process	BP	0.25	2.86e-07	6.13e-06	5.21	3.97e-06	Sema5a/Angpt1/Itga4/Kdr/Tert/Icam1/Tek/Cdh5/Cd248/Ecscr/Ndnf/Angptl4/Hipk1/Col18a1	14
GO:1902414	protein localization to cell junction	BP	0.174	3.05e-07	6.51e-06	5.19	4.22e-06	Gpc6/Nlgn1/Stx1b/Fermt2/Nptx1/Jam3/Slitrk3/Cdh5/Dlg2/Nlgn3/Nptxr/Magi2/Pecam1/Nsg1/Cacng7/Heg1/Dlg4/Dlg5/Abcb1a/Kif5a/Nlgn2	21
GO:0008344	adult locomotory behavior	BP	0.18	3.1e-07	6.58e-06	5.18	4.26e-06	Efnb3/Cacna1c/Hoxd10/Drd4/Ccnd2/Hoxd9/Scn1a/Dab1/Cxcl12/Shank2/Glrb/Enpp1/Kcnma1/Hipk2/Prex2/Arrb2/Atp1a2/Cacna1a/Cacnb4/Nlgn2	20
GO:0099560	synaptic membrane adhesion	BP	0.324	3.13e-07	6.62e-06	5.18	4.29e-06	Gpc6/Lrrc4c/Ptprd/Nlgn1/Lrrc4b/Slitrk3/Epha3/Magi2/Sparcl1/Pcdh17/Ntng1	11
GO:0042326	negative regulation of phosphorylation	BP	0.11	3.16e-07	6.67e-06	5.18	4.32e-06	Hgf/Sfrp2/Angpt1/Cd109/Spink1/Nog/Igf1/Ddr2/Slc8a1/Ptpro/Lrrk2/Mical1/Mapk8ip1/Slc8a3/Pkia/Thy1/Plpp3/Ppm1f/Enpp1/Cdkn1c/Emilin1/Ppef2/Prr5l/Apoe/Rasip1/Pecam1/Ppm1e/Bdkrb2/Pkib/Arrb1/Heg1/Rassf2/Arrb2/Lats2/Smpd1/Psen1/Cav1/Pid1/Grb10/Bmp7/Prkar1b/Twist1/Lax1/Eng	44
GO:0051282	regulation of sequestering of calcium ion	BP	0.172	3.52e-07	7.39e-06	5.13	4.79e-06	Ryr1/Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Htr2a/Xcl1/Selenon/Asph/Pkd2/Xcr1/Ryr3/Slc25a23/Gstm7/Sri/F2r	21
GO:0072080	nephron tubule development	BP	0.186	3.55e-07	7.43e-06	5.13	4.82e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Mef2c/Tcf21/Gli3/Agtr1a/Heyl/Ptch1/Dchs1/Osr1/Aqp11/Fat4/Myc	19
GO:0098698	postsynaptic specialization assembly	BP	0.357	3.78e-07	7.88e-06	5.1	5.11e-06	Gap43/Ptprd/Nlgn1/Lrrc4b/Nptx1/Slitrk3/Nlgn3/Nptxr/Arhgef9/Nlgn2	10
GO:0010524	positive regulation of calcium ion transport into cytosol	BP	0.227	4.16e-07	8.55e-06	5.07	5.54e-06	Cxcr3/Thy1/Aplnr/Agtr1a/Ednra/Adcyap1r1/Asph/Pkd2/Gimap5/Gstm7/Gimap3/Sri/Cav1/F2r/Cd4	15
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	BP	0.184	4.16e-07	8.55e-06	5.07	5.54e-06	Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Hcls1/Fn1/Serpine2/Tek/Ppp1r16b/Prr5l/Fyn/Fgr/Pdgfrb/Pld2/Ror1/F2r/Twist1	19
GO:0021510	spinal cord development	BP	0.184	4.16e-07	8.55e-06	5.07	5.54e-06	Vit/Hoxd10/Dcc/Nog/Dab1/Gdf11/Gli3/Gdf7/Loxl3/Enpp1/Phgdh/Sox12/Dync2h1/Daam2/Tal1/Ptch1/Rab23/Cacna1a/Draxin	19
GO:0060993	kidney morphogenesis	BP	0.184	4.16e-07	8.55e-06	5.07	5.54e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Lrrk2/Tcf21/Gli3/Tshz3/Agtr1a/Ptch1/Dchs1/Osr1/Fat4/Bmp7/Myc	19
GO:0060828	regulation of canonical Wnt signaling pathway	BP	0.129	4.34e-07	8.83e-06	5.05	5.72e-06	Gli1/Sfrp2/Sema5a/Mdk/Wnt11/Nog/Zeb2/Nkd1/Ptpro/Cdh2/Gpc3/Lrrk2/Rbms3/Gprc5b/Gli3/Peg12/Znrf3/Dkk3/Apoe/Daam2/Prickle1/Caprin2/Tle1/Lats2/Psen1/Adgra2/Cav1/Dact1/Nkd2/Tle2/Lrp4/Draxin	32
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	BP	0.213	4.34e-07	8.83e-06	5.05	5.72e-06	Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Hcls1/Fn1/Tek/Prr5l/Fyn/Fgr/Pdgfrb/Pld2/Ror1/F2r	16
GO:0072171	mesonephric tubule morphogenesis	BP	0.213	4.34e-07	8.83e-06	5.05	5.72e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Tcf21/Gli3/Agtr1a/Ptch1/Dchs1/Osr1/Fat4/Myc	16
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	BP	0.314	4.36e-07	8.84e-06	5.05	5.73e-06	Pcdh18/Nlgn1/Cdh2/Cdh6/Cdh13/Pcdhgc3/Cdh10/Cdh5/Pcdh12/Cdh11/Dchs1	11
GO:0051961	negative regulation of nervous system development	BP	0.15	4.52e-07	9.13e-06	5.04	5.91e-06	Prtg/Efnb3/Map2/Sema5a/Nog/Sema5b/Nrp1/Sema7a/Tert/Dab1/Id4/Trpc6/Thy1/Sema3g/Daam2/Nfatc4/Epha7/Syngap1/Psen1/Sema6a/Ulk2/Ptn/Bmp7/Lrp4/Draxin	25
GO:0045165	cell fate commitment	BP	0.122	4.55e-07	9.16e-06	5.04	5.93e-06	Gap43/Ihh/Sfrp2/Wnt6/Ar/AW551984/Wnt11/Hoxd10/Kdr/Ptch2/Tbx2/Hoxa11/Mef2c/Gli3/Glis1/Gdf7/Wnt9a/Loxl3/Prdm1/Jag2/Prickle2/Tbx3/Sox12/Ednra/Tal1/Lhx6/Ptch1/Ets2/Lats2/Psen1/Batf/Spn/Ly9/Hey2/Bcl11b	35
GO:0060047	heart contraction	BP	0.13	4.86e-07	9.73e-06	5.01	6.31e-06	Cacna1c/Sgcd/Kcnd3/Adra1a/Slc8a1/Nos3/Scn4b/Scn1a/Cacna2d1/Ednrb/Stc1/Hopx/Cacna1e/Ank2/Edn3/Calca/Rps6ka2/Gjc1/Ednra/Bin1/Myl3/Pde5a/Slc4a3/Cacna1h/Atp2b4/Ccn2/Apln/Atp1a2/Sri/Cav1/Hey2	31
GO:0042098	T cell proliferation	BP	0.133	4.91e-07	9.81e-06	5.01	6.35e-06	Ihh/Igf1/Cd44/Cxcl12/Mapk8ip1/Dock2/Tnfsf13b/Msn/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Havcr2/Igf2/Nckap1l/Xcl1/Satb1/Stat5b/Fyn/Pde5a/H2-Aa/Dlg5/Zap70/Il12rb1/Spn/Cd4/Myc/Rasal3	30
GO:0060998	regulation of dendritic spine development	BP	0.2	5.07e-07	1.01e-05	5	6.51e-06	Nlgn1/Mef2c/Ppfia2/D16Ertd472e/Kif1a/Nlgn3/Apoe/Caprin2/Bhlhb9/Cux2/Palm/Dlg5/Ngef/Psen1/Zmynd8/Camk1/Nlgn2	17
GO:0001658	branching involved in ureteric bud morphogenesis	BP	0.224	5.12e-07	1.01e-05	5	6.55e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Tcf21/Gli3/Agtr1a/Ptch1/Dchs1/Fat4/Myc	15
GO:1903829	positive regulation of protein localization	BP	0.102	5.43e-07	1.06e-05	4.97	6.89e-06	Igf1/Nlgn1/Tcaf1/Abat/Ccdc88a/Hcls1/Fermt2/Gnai1/Tert/Myo5a/Ano1/Ptp4a3/Prkd1/Tek/Gli3/Lrp2/Rab34/Msn/Epha3/Nlgn3/Vegfc/Cd38/Prr5l/Crocc/Pecam1/Tmem35a/Arrb1/Tnfaip6/Stac2/Abcg1/Asph/Frmd4a/Fyn/Wipf1/Mgat3/Dzip1/Dlg4/Atp2b4/Psen1/Sri/Ptn/Meak7/Glis2/Nkd2/Pfkm/Golph3l/Cacnb4/Lrp4/Camk1/Nlgn2	50
GO:0014031	mesenchymal cell development	BP	0.189	5.51e-07	1.08e-05	4.97	6.98e-06	Sema5a/Zeb2/Sema5b/Nrp1/Sema7a/Cdh2/Fn1/Ednrb/Edn3/Ednra/Heyl/Sema3g/Kitl/Sema6a/Bmp7/Hey2/Hand2/Twist1	18
GO:0003203	endocardial cushion morphogenesis	BP	0.306	6.01e-07	1.17e-05	4.93	7.58e-06	Nog/Tbx2/Nos3/Aplnr/Tbx3/Heyl/Snai1/Dchs1/Bmp7/Twist1/Eng	11
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	BP	0.124	6.51e-07	1.26e-05	4.9	8.15e-06	Ptprz1/Hgf/Sfrp2/Angpt1/Spink1/Igf1/Adra1a/Nrp1/Hcls1/Cd44/Cspg4/Areg/Icam1/Gprc5b/Thy1/Plpp3/Kit/Vegfc/Nox4/Pecam1/Igf2/Kitl/Htr2a/Epha7/Arrb2/Fyn/Dlg4/Psen1/Pdgfrb/Cav1/Enpp2/Cd4/Lrp4	33
GO:0120032	regulation of plasma membrane bounded cell projection assembly	BP	0.137	6.52e-07	1.26e-05	4.9	8.15e-06	Gap43/Evl/Nlgn1/Ccdc88a/Nrp1/Adamts16/Abi3/Pfn2/Icam1/Podxl/Abi2/Kit/Kctd17/Rp1/Eps8l1/Crocc/Daam2/Ttbk2/Dzip1/Palm/Dpysl3/Dync2li1/Cdc42ep5/Cep97/Def8/Cav1/Atmin/Zmynd8	28
GO:0051098	regulation of binding	BP	0.108	6.53e-07	1.26e-05	4.9	8.15e-06	Map2/Angpt1/Lef1/Itga4/Nog/Igf1/Zfp462/Runx1t1/Tert/Lrrk2/Hopx/Plxnd1/Lfng/Ccm2l/Apoe/Caprin2/Zc4h2/Dysf/Pkd1/Hipk2/Arrb1/Nfatc4/Twist2/Arrb2/Arhgap28/Ttbk2/Cldn5/Dzip1/Habp4/Mfng/Zfp90/Psen1/Sri/Nes/Hipk1/Cav1/Dact1/Gpsm1/Hey2/Hand2/Camk1/Myc/Twist1	43
GO:0098815	modulation of excitatory postsynaptic potential	BP	0.233	7.14e-07	1.37e-05	4.86	8.88e-06	Nlgn1/Celf4/Stx1b/Drd4/Lrrk2/Grin2b/Tbc1d24/Slc8a3/Nlgn3/Dlg4/Cux2/Zmynd8/Prkar1b/Nlgn2	14
GO:0072028	nephron morphogenesis	BP	0.195	7.18e-07	1.37e-05	4.86	8.89e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Tcf21/Gli3/Agtr1a/Ptch1/Dchs1/Osr1/Fat4/Bmp7/Myc	17
GO:0045860	positive regulation of protein kinase activity	BP	0.112	7.19e-07	1.37e-05	4.86	8.89e-06	Angpt1/Agap2/Igf1/Zeb2/Ddr2/Adra1a/Ccdc88a/Fermt2/Drd4/Ccnd2/Lrrk2/Areg/Dab1/Pik3r6/Gprc5b/Edn3/Calca/Kit/Mmd/Vegfc/Agtr1a/Nox4/Kitl/Htr2a/Pkd1/Rassf2/Arrb2/Pkd2/Pde5a/Dlg4/Atp2b4/Acsl1/Psen1/Lat/Pdgfrb/Map4k2/C1qtnf9/Fgd2/Cd4/Camk1	40
GO:0007266	Rho protein signal transduction	BP	0.159	7.33e-07	1.39e-05	4.86	9.03e-06	Adra1a/Nrp1/Cdh2/Lpar4/Arhgef25/Cdh13/Eps8l1/Agtr1a/Apoe/Rasip1/Ednra/Pecam1/Arap3/Arrb1/Heg1/Dlc1/Net1/Cdc42ep5/Pdgfrb/Nradd/F2r/Plekhg5	22
GO:0019233	sensory perception of pain	BP	0.154	7.43e-07	1.41e-05	4.85	9.12e-06	Kcnd2/Scn1a/Ednrb/Ano1/Grin2b/Cxcl12/Cacna1e/Calca/Ndn/Mme/Dlg2/Ednra/Kcnc4/Htr2a/Kcnip3/Arrb2/Fyn/Cacna1h/Scn3a/Cacna1a/F2r/Prkar1b/Nlgn2	23
GO:0048872	homeostasis of number of cells	BP	0.11	7.51e-07	1.42e-05	4.85	9.18e-06	Tex15/Pla2g10/Col14a1/Gprasp2/Emcn/Nos3/Crispld1/P4htm/Hcls1/Cd44/Ets1/Cdh2/Mef2c/Jam3/Flvcr1/Plcb1/Myct1/Sh2b2/Flt3/Tnfsf13b/Dock10/Coro1a/Armcx1/Kit/Heph/Enpp1/Nckap1l/Zfp251/Kitl/Tal1/Rassf2/Stat5b/Akt3/Septin4/Gimap5/Fstl1/Gimap3/Lat/Glis2/F2r/Il7r	41
GO:1902905	positive regulation of supramolecular fiber organization	BP	0.142	7.55e-07	1.42e-05	4.85	9.19e-06	Sema5a/Wnt11/Evl/Ccdc88a/Nrp1/Fermt2/Wasf3/Pfn2/Icam1/Abi2/Ppm1f/Limch1/Nox4/Arhgef15/Ppm1e/Scin/Bin1/Nckap1l/Nin/Slain1/Ccn2/Efemp2/Cdc42ep5/Psen1/Cav1/Plek	26
GO:0061028	establishment of endothelial barrier	BP	0.25	7.59e-07	1.42e-05	4.85	9.19e-06	Ednrb/Icam1/Plcb1/Cdh5/Msn/Ppp1r16b/Robo4/Ednra/Pecam1/Cldn5/Akap11/Cldn1/S1pr3	13
GO:0006813	potassium ion transport	BP	0.128	7.67e-07	1.43e-05	4.85	9.26e-06	Kcnk3/Kcnb2/Nalcn/Slc1a3/Kcnj3/Kcna6/Kcnd2/Kcnd3/Slc12a8/Nos3/Kcnq5/Slc9a7/Slc24a4/Slc24a3/Ank2/Edn3/Kcnma1/Slc9a5/Kcnc4/Bin1/Htr2a/Kcnip3/Slc12a4/Pkd2/Fhl1/Kcng4/Ptger3/Atp1a2/Cav1/Kcnq4/Kcnh1	31
GO:0060560	developmental growth involved in morphogenesis	BP	0.121	7.93e-07	1.47e-05	4.83	9.54e-06	Sfrp2/Map2/Sema5a/Wnt11/Itga4/Zeb2/St8sia2/Tbx2/Sema5b/Cpne5/Nrp1/Nkd1/Sema7a/Fn1/Areg/Cxcl12/Edn3/Eif2ak4/Postn/Ndn/Nlgn3/Apoe/Ednra/Sema3g/Slc23a2/Nin/Epha7/Cacng7/Sema6a/Ulk2/Nrn1/Cyfip2/Slit3/Draxin	34
GO:0030282	bone mineralization	BP	0.164	8.02e-07	1.48e-05	4.83	9.6e-06	Wnt11/Igf1/Ddr2/Pkdcc/Slc8a1/Gpc3/Mef2c/Osr2/Slc24a3/Nell1/Pth1r/Mgp/Enpp1/Ltbp3/Osr1/Fgr/Ptn/Dnm3os/Bmp7/Ank/Twist1	21
GO:0090257	regulation of muscle system process	BP	0.125	8.08e-07	1.49e-05	4.83	9.65e-06	Cacna1c/Ryr1/Igf1/Npnt/Adra1a/Abat/Slc8a1/Nos3/Mef2c/Stc1/Ank2/Slc8a3/Calca/Gucy1a1/Kit/Kcnma1/Bin1/Myl3/Cmya5/Selenon/Pde5a/Pi16/Calcrl/Cacna1h/Ptger3/Atp2b4/Ccn2/Atp1a2/Sri/Cav1/F2r/Hand2	32
GO:0007613	memory	BP	0.149	8.25e-07	1.52e-05	4.82	9.82e-06	Mdk/Cyp7b1/Nog/Igf1/Aph1b/Drd4/Ccnd2/Chst10/B4galt2/Grin2b/Shank2/Plcb1/Eif2ak4/Slc8a3/Scn2a/Apoe/Igf2/Htr2a/Nfatc4/Pde5a/Cux2/Psen1/Ptn/Itga8	24
GO:0001738	morphogenesis of a polarized epithelium	BP	0.193	8.5e-07	1.56e-05	4.81	1.01e-05	Sfrp2/Wnt11/Nkd1/Gpc3/Foxf1/Myo9a/Msn/Znrf3/Cplane1/Sh3bp1/Dchs1/Nphp1/Fzd2/Dlg5/Brsk1/Fat4/Dact1	17
GO:0008217	regulation of blood pressure	BP	0.132	8.76e-07	1.6e-05	4.8	1.03e-05	Ar/Cacna1c/Kdr/Ddah1/Adra1a/Abat/Nos3/Ptpro/Npr3/P2rx2/Adamts16/Ednrb/Enpep/Edn3/Calca/Rps6ka2/Postn/Gucy1a1/Emilin1/Vegfc/Agtr1a/Ednra/Bdkrb2/Trhde/Apln/Atp1a2/Lvrn/F2r/Eng	29
GO:0060491	regulation of cell projection assembly	BP	0.135	8.78e-07	1.6e-05	4.8	1.03e-05	Gap43/Evl/Nlgn1/Ccdc88a/Nrp1/Adamts16/Abi3/Pfn2/Icam1/Podxl/Abi2/Kit/Kctd17/Rp1/Eps8l1/Crocc/Daam2/Ttbk2/Dzip1/Palm/Dpysl3/Dync2li1/Cdc42ep5/Cep97/Def8/Cav1/Atmin/Zmynd8	28
GO:0097178	ruffle assembly	BP	0.267	9.53e-07	1.73e-05	4.76	1.12e-05	Evl/Nlgn1/Cspg4/Aif1l/Pfn2/Icam1/Sh3bp1/Eps8l1/Arhgef26/Def8/Pdgfrb/Cav1	12
GO:2000351	regulation of endothelial cell apoptotic process	BP	0.245	9.62e-07	1.74e-05	4.76	1.13e-05	Sema5a/Angpt1/Itga4/Kdr/Tert/Icam1/Tek/Cdh5/Cd248/Ecscr/Ndnf/Angptl4/Col18a1	13
GO:0051209	release of sequestered calcium ion into cytosol	BP	0.168	9.83e-07	1.77e-05	4.75	1.15e-05	Ryr1/Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Htr2a/Xcl1/Selenon/Asph/Pkd2/Xcr1/Ryr3/Gstm7/Sri/F2r	20
GO:0033627	cell adhesion mediated by integrin	BP	0.191	1e-06	1.8e-05	4.75	1.16e-05	Epha8/Cyp1b1/Itga4/Npnt/Col16a1/Itgb7/Icam1/Jam3/Itga1/Podxl/Plpp3/Itgal/Emilin1/Itga7/Nckap1l/Itga8/Itgb4	17
GO:1901019	regulation of calcium ion transmembrane transporter activity	BP	0.191	1e-06	1.8e-05	4.75	1.16e-05	Drd4/Cacna2d1/Myo5a/Ank2/Cracr2a/Dysf/Stac2/Selenon/Asph/Pkd2/Rrad/Gnb5/Gstm7/Atp1a2/Sri/Cacna1a/Cacnb4	17
GO:0106027	neuron projection organization	BP	0.174	1.03e-06	1.83e-05	4.74	1.19e-05	Nlgn1/Lrrk2/Grin2b/Ppfia2/Dock10/Abi2/Kif1a/Nlgn3/Apoe/Caprin2/Bhlhb9/Fyn/Dlg4/Cux2/Abcd2/Ngef/Psen1/Zmynd8/Zfp365	19
GO:0051492	regulation of stress fiber assembly	BP	0.182	1.04e-06	1.85e-05	4.73	1.2e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Arhgap6/Nox4/Arhgef15/Tmeff2/Ppm1e/Dlc1/Arhgap28/Ccn2	18
GO:0042063	gliogenesis	BP	0.111	1.06e-06	1.87e-05	4.73	1.21e-05	Gap43/Ptprz1/Mdk/Lef1/Apcdd1/Nog/Igf1/Lamc3/Cspg4/Tert/Cdh2/Fn1/Wasf3/Areg/Dab1/Id4/Serpine2/Gli3/Slc8a3/Lrp2/Plpp3/Ndn/Matn2/Nlgn3/Enpp1/Phgdh/Daam2/Bin1/Zcchc24/Tal1/Nrros/Psen1/Ptn/Tppp/Itgb4/Enpp2/Vcan/Myc/Zfp365	39
GO:0017157	regulation of exocytosis	BP	0.126	1.09e-06	1.93e-05	4.72	1.25e-05	Nlgn1/Syt13/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Myo5a/Foxf1/Pfn2/Mical1/Ppfia2/Htr1b/Cadps/Syt7/Nckap1l/Htr2a/Ncs1/Cd84/Cacna1h/Fgr/Septin4/Slc4a8/Rab27a/Nrn1/Cacna1a/Pld2/Pdcd6ip/Cacnb4/Kcnh1	31
GO:0050982	detection of mechanical stimulus	BP	0.226	1.09e-06	1.93e-05	4.72	1.25e-05	Col11a1/Igf1/Scn1a/Grin2b/Serpine2/Cxcl12/Kit/Htr2a/Pkd1/Pkd2/Fyn/Piezo2/Pkdrej/Myc	14
GO:0051283	negative regulation of sequestering of calcium ion	BP	0.167	1.13e-06	1.98e-05	4.7	1.28e-05	Ryr1/Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Htr2a/Xcl1/Selenon/Asph/Pkd2/Xcr1/Ryr3/Gstm7/Sri/F2r	20
GO:0006937	regulation of muscle contraction	BP	0.146	1.16e-06	2.03e-05	4.69	1.31e-05	Cacna1c/Ryr1/Npnt/Adra1a/Abat/Slc8a1/Stc1/Ank2/Slc8a3/Calca/Gucy1a1/Kit/Kcnma1/Bin1/Myl3/Pde5a/Calcrl/Cacna1h/Ptger3/Ccn2/Atp1a2/Sri/Cav1/F2r	24
GO:1904019	epithelial cell apoptotic process	BP	0.165	1.29e-06	2.24e-05	4.65	1.45e-05	Sema5a/Angpt1/Mdk/Itga4/Kdr/Igf1/Tert/Bok/Icam1/Tek/Cdh5/Jag2/Cd248/Ecscr/Ednra/Ndnf/Arrb2/Angptl4/Hipk1/Col18a1	20
GO:0007263	nitric oxide mediated signal transduction	BP	0.36	1.35e-06	2.35e-05	4.63	1.52e-05	Spink1/Nos3/Cbs/Gucy1a2/Gucy1a1/Apoe/Ndnf/Pde5a/Atp2b4	9
GO:0110020	regulation of actomyosin structure organization	BP	0.171	1.37e-06	2.37e-05	4.63	1.53e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Mef2c/Pfn2/Ppm1f/Limch1/Arhgap6/Nox4/Arhgef15/Tmeff2/Ppm1e/Dlc1/Arhgap28/Ccn2	19
GO:0001656	metanephros development	BP	0.187	1.39e-06	2.39e-05	4.62	1.55e-05	Hoxd11/Hoxa11/Gpc3/Id3/Osr2/Gdf11/Tcf21/Gli3/Tshz3/Ptch1/Osr1/Dlg5/Fat4/Pdgfrb/Itga8/Bmp7/Myc	17
GO:0031032	actomyosin structure organization	BP	0.131	1.42e-06	2.43e-05	4.61	1.58e-05	Kank4/Wnt11/Evl/Frmd3/Epb41l3/Phldb2/Ccdc88a/Nrp1/Fermt2/Tmod2/Mef2c/Pfn2/Ppm1f/Limch1/Arhgap6/Nox4/Arhgef15/Cnn2/Tmeff2/Ppm1e/Arrb1/Flnc/Dlc1/Arhgap28/Cnn3/Ccn2/Pdgfrb/Pdcd6ip	28
GO:0046578	regulation of Ras protein signal transduction	BP	0.134	1.43e-06	2.43e-05	4.61	1.58e-05	Igf1/Adra1a/Nrp1/Cdh2/Rasa3/Lpar4/Arhgef25/Dock2/Sh2b2/Syde1/Sh3bp1/Eps8l1/Apoe/Rasip1/Kitl/Arap3/Arrb1/Heg1/Dlc1/Net1/Syngap1/Mapre2/Pdgfrb/Dennd4a/Iqsec3/F2r/Rasal3	27
GO:0070661	leukocyte proliferation	BP	0.109	1.45e-06	2.47e-05	4.61	1.6e-05	Ihh/Lef1/Igf1/Cd44/Npr3/Mef2c/Cxcl12/Mapk8ip1/Dock2/Flt3/Tnfsf13b/Msn/Prdm1/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Cd38/Havcr2/Igf2/Nckap1l/Kitl/Xcl1/Satb1/Stat5b/Fyn/Pde5a/Csf2rb/H2-Aa/Dlg5/Impdh1/Zap70/Il12rb1/Spn/Il7r/Cd4/Myc/Rasal3	40
GO:0006790	sulfur compound metabolic process	BP	0.113	1.47e-06	2.49e-05	4.6	1.61e-05	Acsl6/Angpt1/Hmgcs2/Acacb/Cbs/Chst2/Spock2/Ednrb/Mical1/Tpst1/Egflam/Gamt/Gstm6/Them5/Mamdc2/Cth/Chst1/Enpp1/Phgdh/Nox4/Ednra/Ndnf/Bgn/Acot7/Stat5b/Dse/Acsl1/Xylt1/Gstm7/Gstm1/Ggt7/Cacna1a/Sult1a1/Gstk1/Papss2/Suclg2/Acot6	37
GO:0046928	regulation of neurotransmitter secretion	BP	0.164	1.47e-06	2.49e-05	4.6	1.61e-05	Nlgn1/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Htr1b/Kcnc4/Htr2a/Ncs1/Slc4a8/Nrn1/Cacna1a/Cacnb4/Kcnh1	20
GO:0001837	epithelial to mesenchymal transition	BP	0.148	1.51e-06	2.53e-05	4.6	1.64e-05	Sfrp2/Mdk/Lef1/Wnt11/Nog/Mark1/Phldb2/Fermt2/Erg/Has2/Loxl3/Epha3/Tbx3/Ednra/Spred3/Heyl/Snai1/Il17rd/Dlg5/Bmp7/Hey2/Twist1/Eng	23
GO:0048593	camera-type eye morphogenesis	BP	0.148	1.51e-06	2.53e-05	4.6	1.64e-05	Stra6/Ihh/Sdk2/Kdr/Tbx2/Arl6/Tenm3/Obsl1/Gdf11/Gli3/Ptprm/Thy1/Zeb1/Abi2/Rp1/Tsku/Hipk2/Rorb/Fat3/Ptn/Hipk1/Bmp7/Twist1	23
GO:0030217	T cell differentiation	BP	0.116	1.51e-06	2.53e-05	4.6	1.64e-05	Ihh/Mdk/Lef1/Cd83/Cd44/Itk/Cd3g/Pik3r6/Gli3/Dock2/Flt3/Lfng/Loxl3/Zeb1/Prdm1/Jag2/Cd1d1/Kit/Enpp1/Cracr2a/Sox12/Nckap1l/Satb1/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il2rg/Batf/Spn/Ly9/Il7r/Cd4/Bcl11b	35
GO:0048588	developmental cell growth	BP	0.119	1.62e-06	2.71e-05	4.57	1.75e-05	Map2/Sema5a/Itga4/Col14a1/Igf1/Zeb2/St8sia2/Sema5b/Adra1a/Cpne5/Nrp1/Sema7a/Fn1/Cxcl12/Edn3/Eif2ak4/Postn/Ndn/Nlgn3/Apoe/Ednra/Sema3g/Slc23a2/Nin/Epha7/Cacng7/Pi16/Sema6a/Ulk2/Nrn1/Cyfip2/Slit3/Draxin	33
GO:0002685	regulation of leukocyte migration	BP	0.128	1.67e-06	2.79e-05	4.55	1.81e-05	Mdk/Itga4/Chst2/Icam1/Jam3/Cxcr3/Cxcl12/Edn3/Plcb1/Thy1/Msn/Il27ra/Emilin1/Vegfc/Sele/Ednra/Pecam1/Cd200/Dysf/Nckap1l/Kitl/Xcl1/Tnfaip6/Ptger3/St3gal4/Mpp1/Ptn/Spn/Jam2	29
GO:0072078	nephron tubule morphogenesis	BP	0.193	1.83e-06	3.03e-05	4.52	1.96e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Tcf21/Gli3/Agtr1a/Ptch1/Dchs1/Osr1/Fat4/Myc	16
GO:0034764	positive regulation of transmembrane transport	BP	0.123	1.83e-06	3.03e-05	4.52	1.96e-05	Cacna1c/Acsl6/Igf1/Tcaf1/Drd4/Tert/Gpc3/Cacna2d1/Myo5a/Cxcr3/Ank2/Edn3/Plcb1/Trpc6/Thy1/Aplnr/Nlgn3/Cracr2a/Agtr1a/Ednra/Stac2/Asph/Pkd2/Acsl1/Gstm7/Psen1/Abcb1a/Sri/Cacnb4/F2r/Irs1	31
GO:0001666	response to hypoxia	BP	0.13	1.88e-06	3.1e-05	4.51	2.01e-05	Kcnk3/Kcnd2/Kdr/Ryr1/Ddah1/Abat/Slc8a1/Cbs/P2rx2/Pygm/Tert/Mmp2/Grin2b/Tek/Slc8a3/Scn2a/Vegfc/Cd38/Kcnma1/Ednra/Ndnf/Cav1/Cpeb1/Pld2/Hif3a/Myc/Twist1/Eng	28
GO:0022612	gland morphogenesis	BP	0.146	1.89e-06	3.1e-05	4.51	2.01e-05	Gli1/Hgf/Ar/Mdk/Cyp7b1/Nog/Igf1/Tbx2/Nrp1/Cd44/Areg/Mmp2/Id4/Gli3/Plxnd1/Gdf7/Msn/Tbx3/Ptch1/Ptn/Cav1/Edar/Bmp7	23
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	BP	0.135	1.9e-06	3.1e-05	4.51	2.01e-05	Ptprz1/Hgf/Angpt1/Igf1/Adra1a/Nrp1/Hcls1/Cd44/Cspg4/Areg/Icam1/Gprc5b/Plpp3/Kit/Vegfc/Nox4/Pecam1/Igf2/Kitl/Htr2a/Arrb2/Fyn/Dlg4/Enpp2/Cd4/Lrp4	26
GO:0043535	regulation of blood vessel endothelial cell migration	BP	0.183	1.9e-06	3.1e-05	4.51	2.01e-05	Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Mef2c/Prkd1/Vash1/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Hdac9/Akt3/Atp2b4	17
GO:1904035	regulation of epithelial cell apoptotic process	BP	0.183	1.9e-06	3.1e-05	4.51	2.01e-05	Sema5a/Angpt1/Mdk/Itga4/Kdr/Igf1/Tert/Bok/Icam1/Tek/Cdh5/Cd248/Ecscr/Ndnf/Arrb2/Angptl4/Col18a1	17
GO:0031503	protein-containing complex localization	BP	0.132	1.91e-06	3.1e-05	4.51	2.01e-05	Gpc6/Sgcd/Tub/Nlgn1/Lrrc7/Cep112/Stx1b/Drd4/Wdr35/Nptx1/Exoc3l/Ift57/Dlg2/Nptxr/Magi2/Dync2h1/Ttc26/Arl3/Nsg1/Cacng7/Dzip1/Dlg4/Dync2li1/Bbs1/Ift81/Kif5a/Zfp365	27
GO:0010632	regulation of epithelial cell migration	BP	0.124	1.92e-06	3.12e-05	4.51	2.02e-05	Sema5a/Angpt1/Kdr/Igf1/Evl/Nos3/Nrp1/Ets1/Mef2c/Pfn2/Prkd1/Stc1/Tek/Has2/Vash1/Ptprm/Plpp3/Ppm1f/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Hdac9/Akt3/Atp2b4/Arsb/Adgra2/Mapre2/Enpp2	30
GO:0060675	ureteric bud morphogenesis	BP	0.203	1.97e-06	3.17e-05	4.5	2.06e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Tcf21/Gli3/Agtr1a/Ptch1/Dchs1/Fat4/Myc	15
GO:1903510	mucopolysaccharide metabolic process	BP	0.203	1.97e-06	3.17e-05	4.5	2.06e-05	Angpt1/Cd44/Spock2/Ednrb/Has2/Egflam/Mamdc2/Chst1/Ednra/Ndnf/Tnfaip6/Bgn/Dse/Habp4/Xylt1	15
GO:0051100	negative regulation of binding	BP	0.142	2e-06	3.21e-05	4.49	2.08e-05	Map2/Lef1/Itga4/Nog/Zfp462/Lrrk2/Ccm2l/Dysf/Nfatc4/Twist2/Arrb2/Arhgap28/Ttbk2/Habp4/Zfp90/Psen1/Sri/Nes/Cav1/Dact1/Hey2/Hand2/Camk1/Myc	24
GO:0032835	glomerulus development	BP	0.215	2.01e-06	3.21e-05	4.49	2.08e-05	Angpt1/Nog/Ptpro/Ednrb/Mef2c/Nid1/Enpep/Tek/Tcf21/Ednra/Heyl/Osr1/Pdgfrb/Bmp7	14
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	BP	0.25	2.02e-06	3.23e-05	4.49	2.09e-05	Wnt11/Lrrc7/Foxf1/Myo9a/Msn/Dlg2/Prickle2/Lin7a/Sh3bp1/Pard3b/Dlg5/Pdcd6ip	12
GO:2001257	regulation of cation channel activity	BP	0.138	2.07e-06	3.3e-05	4.48	2.14e-05	Nlgn1/Drd4/Cacna2d1/Myo5a/Mef2c/Ank2/Nlgn3/Cracr2a/Prrt1/Ednra/Dysf/Cacng7/Stac2/Selenon/Asph/Pkd2/Rrad/Dlg4/Gnb5/Gstm7/Sri/Cav1/Cacna1a/Cacnb4/Nlgn2	25
GO:0060973	cell migration involved in heart development	BP	0.4	2.09e-06	3.33e-05	4.48	2.16e-05	Nrp1/Ednra/Dchs1/Pdgfrb/Bmp7/Hand2/Twist1/Eng	8
GO:0072203	cell proliferation involved in metanephros development	BP	0.6	2.17e-06	3.42e-05	4.47	2.22e-05	Gpc3/Ptch1/Osr1/Pdgfrb/Bmp7/Myc	6
GO:2000807	regulation of synaptic vesicle clustering	BP	0.6	2.17e-06	3.42e-05	4.47	2.22e-05	Nlgn1/Cdh2/Nlgn3/Magi2/Pcdh17/Nlgn2	6
GO:0042060	wound healing	BP	0.107	2.17e-06	3.42e-05	4.47	2.22e-05	Cd109/Kdr/Nog/Igf1/Evl/Ddr2/Phldb2/Tfpi/Abat/Cd44/Fermt2/Fn1/Fkbp10/Serpine2/Plpp3/Procr/Ccm2l/Tsku/Apoe/Syt7/Cnn2/Pecam1/Tmeff2/Ndnf/Dysf/Pros1/Abi3bp/Clec7a/Ptger3/St3gal4/Smpd1/Rab27a/Cav1/Fgfr1op2/Cldn1/F2r/Wfdc1/Plek/Papss2/Eng	40
GO:0043393	regulation of protein binding	BP	0.128	2.26e-06	3.55e-05	4.45	2.3e-05	Map2/Angpt1/Itga4/Nog/Tert/Lrrk2/Hopx/Plxnd1/Lfng/Ccm2l/Apoe/Caprin2/Dysf/Pkd1/Hipk2/Arrb1/Nfatc4/Arrb2/Ttbk2/Cldn5/Dzip1/Mfng/Psen1/Nes/Cav1/Dact1/Camk1/Myc	28
GO:0031529	ruffle organization	BP	0.228	2.34e-06	3.66e-05	4.44	2.37e-05	Evl/Nlgn1/Cspg4/Aif1l/Pfn2/Icam1/Sh3bp1/Eps8l1/Arhgef26/Def8/Pdgfrb/Cav1/Plek	13
GO:0032231	regulation of actin filament bundle assembly	BP	0.165	2.37e-06	3.71e-05	4.43	2.4e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Arhgap6/Nox4/Arhgef15/Tmeff2/Ppm1e/Dlc1/Arhgap28/Ccn2/Plek	19
GO:0046651	lymphocyte proliferation	BP	0.11	2.44e-06	3.79e-05	4.42	2.46e-05	Ihh/Lef1/Igf1/Cd44/Mef2c/Cxcl12/Mapk8ip1/Dock2/Flt3/Tnfsf13b/Msn/Prdm1/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Cd38/Havcr2/Igf2/Nckap1l/Xcl1/Satb1/Stat5b/Fyn/Pde5a/H2-Aa/Dlg5/Impdh1/Zap70/Il12rb1/Spn/Il7r/Cd4/Myc/Rasal3	37
GO:0072088	nephron epithelium morphogenesis	BP	0.188	2.54e-06	3.94e-05	4.4	2.56e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Tcf21/Gli3/Agtr1a/Ptch1/Dchs1/Osr1/Fat4/Myc	16
GO:0071526	semaphorin-plexin signaling pathway	BP	0.245	2.56e-06	3.96e-05	4.4	2.57e-05	Sema5a/Plxnb1/Sema5b/Nrp1/Sema7a/Mef2c/Plxnd1/Sh3bp1/Ednra/Sema3g/Sema6a/Hand2	12
GO:0030038	contractile actin filament bundle assembly	BP	0.164	2.71e-06	4.18e-05	4.38	2.71e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Arhgap6/Nox4/Arhgef15/Tmeff2/Ppm1e/Arrb1/Dlc1/Arhgap28/Ccn2	19
GO:0043149	stress fiber assembly	BP	0.164	2.71e-06	4.18e-05	4.38	2.71e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Arhgap6/Nox4/Arhgef15/Tmeff2/Ppm1e/Arrb1/Dlc1/Arhgap28/Ccn2	19
GO:0018209	peptidyl-serine modification	BP	0.107	2.77e-06	4.26e-05	4.37	2.76e-05	Hgf/Sfrp2/Angpt1/Hcls1/Cd44/Spock2/Lrrk2/Pfn2/Prkd1/Tek/Egflam/Galnt16/Rps6ka2/Mamdc2/Ppm1f/Caprin2/Ndnf/Dclk2/Bdkrb2/Pkd1/Hipk2/Rps6ka5/Arrb1/Bgn/Poglut2/Rassf2/Arrb2/Ttbk2/Akt3/Atp2b4/Lats2/Brsk1/Ulk2/Naa11/Hipk1/Cav1/Sh2d3c/Mknk2/Camk1	39
GO:0001764	neuron migration	BP	0.133	2.81e-06	4.3e-05	4.37	2.79e-05	Ptprz1/Mdk/Dcc/Mark1/Nrp1/Dab1/Mef2c/Cxcl12/Tbc1d24/Cep85l/Ndn/Gpr173/Matn2/Ndnf/Lhx6/Lrp12/Neo1/Nr2f1/Fyn/Septin4/Fat3/Bbs1/Psen1/Sema6a/Ntng1/Twist1	26
GO:0014821	phasic smooth muscle contraction	BP	0.333	2.85e-06	4.35e-05	4.36	2.82e-05	Tbx2/P2rx2/Ednrb/Edn3/Tshz3/Kit/Tbx3/Kcnma1/Ptger3	9
GO:0070509	calcium ion import	BP	0.177	3e-06	4.57e-05	4.34	2.96e-05	Cacna1c/Spink1/Slc8a1/Slc24a4/Stc1/Cxcl12/Cacna1e/Slc8a3/Nalf1/Agtr1a/Dysf/Pkd2/Fyn/Cacna1h/Slc25a23/Pdgfrb/Cacna1a	17
GO:0050769	positive regulation of neurogenesis	BP	0.114	3.01e-06	4.57e-05	4.34	2.96e-05	Ptprz1/Sema5a/Mdk/Kdr/Plxnb1/Ptprd/Nog/Igf1/Zeb2/Nrp1/Sema7a/Fn1/Serpine2/Cxcl12/Tbc1d24/Obsl1/Gli3/Plxnd1/Lrp2/Kit/Mme/Vegfc/Apoe/Caprin2/Bin1/Nin/Chodl/Bhlhb9/Cux2/Ptn/Enpp2/Myc/Zfp365/Numbl	34
GO:0035725	sodium ion transmembrane transport	BP	0.147	3.07e-06	4.65e-05	4.33	3.02e-05	Nalcn/Hecw2/Slc6a2/Slc8a1/Scn4b/Drd4/Fxyd5/Scn1a/Slc9a7/Slc24a4/Slc24a3/Plcb1/Slc8a3/Slc6a15/Scn2a/Slc9a5/Osr1/Pkd2/Atp2b4/Scn3a/Atp1a2/Slc4a8	22
GO:0032943	mononuclear cell proliferation	BP	0.109	3.22e-06	4.83e-05	4.32	3.13e-05	Ihh/Lef1/Igf1/Cd44/Mef2c/Cxcl12/Mapk8ip1/Dock2/Flt3/Tnfsf13b/Msn/Prdm1/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Cd38/Havcr2/Igf2/Nckap1l/Xcl1/Satb1/Stat5b/Fyn/Pde5a/H2-Aa/Dlg5/Impdh1/Zap70/Il12rb1/Spn/Il7r/Cd4/Myc/Rasal3	37
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	BP	0.24	3.22e-06	4.83e-05	4.32	3.13e-05	Hmcn1/Mcam/Itga4/Ptprd/Nlgn1/Cdh2/Tenm3/Adgrl1/Itgal/Sele/Dchs1/Fat4	12
GO:0048592	eye morphogenesis	BP	0.134	3.41e-06	5.12e-05	4.29	3.32e-05	Stra6/Ihh/Sdk2/Kdr/Tbx2/Arl6/Tenm3/Obsl1/Gdf11/Gli3/Ptprm/Thy1/Zeb1/Prdm1/Abi2/Rp1/Tsku/Col5a2/Hipk2/Rorb/Fat3/Ptn/Hipk1/Bmp7/Twist1	25
GO:0001570	vasculogenesis	BP	0.175	3.48e-06	5.2e-05	4.28	3.37e-05	Angpt1/Kdr/Nrp1/Foxf1/Tek/Has2/Aplnr/Enpp1/Rasip1/Gjc1/Tie1/Heg1/Egfl7/Pdgfrb/Cav1/Hey2/Eng	17
GO:0003170	heart valve development	BP	0.22	3.54e-06	5.27e-05	4.28	3.42e-05	Stra6/Nos3/Mef2c/Erg/Prdm1/Aplnr/Emilin1/Tie1/Heyl/Dchs1/Hey2/Slit3/Twist1	13
GO:0030048	actin filament-based movement	BP	0.155	3.59e-06	5.34e-05	4.27	3.46e-05	Cacna1c/Sgcd/Evl/Kcnd3/Scn4b/Scn1a/Cacna2d1/Myo5a/Stc1/Ank2/Limch1/Bin1/Epdr1/Myo1f/Wipf1/Cacna1h/Ptger3/Atp1a2/Sri/Cav1	20
GO:0060326	cell chemotaxis	BP	0.111	3.67e-06	5.44e-05	4.26	3.53e-05	Cxcl15/Hgf/Sema5a/Mdk/Lef1/Kdr/Cyp7b1/Nrp1/Ptpro/Ednrb/Prkd1/Jam3/Cxcr3/Cxcl12/Edn3/Itga1/Calca/Coro1a/Kit/Vegfc/Agtr1a/Ednra/Dysf/Nckap1l/Xcl1/Tnfaip6/Arrb2/Xcr1/Mpp1/Pdgfrb/Ptn/Elmo2/Enpp2/Plekhg5/Eng	35
GO:0071772	response to BMP	BP	0.134	3.76e-06	5.55e-05	4.26	3.6e-05	Sfrp2/Lef1/Kdr/Nog/Kcnd3/Rnf165/Fst/Vstm2a/Gpc3/Zfp423/Cdh5/Gdf7/Lrp2/Heyl/Adamts7/Hipk2/Kcp/Tnfaip6/Smad9/Neo1/Fstl1/Cav1/Tmprss6/Bmp7/Eng	25
GO:0071773	cellular response to BMP stimulus	BP	0.134	3.76e-06	5.55e-05	4.26	3.6e-05	Sfrp2/Lef1/Kdr/Nog/Kcnd3/Rnf165/Fst/Vstm2a/Gpc3/Zfp423/Cdh5/Gdf7/Lrp2/Heyl/Adamts7/Hipk2/Kcp/Tnfaip6/Smad9/Neo1/Fstl1/Cav1/Tmprss6/Bmp7/Eng	25
GO:0060249	anatomical structure homeostasis	BP	0.11	3.83e-06	5.63e-05	4.25	3.65e-05	Tex15/Ihh/Angpt1/Kdr/Col14a1/Tub/Nos3/P2rx2/Calca/Flt3/Pth1r/Pbld2/Coro1a/Ldb2/Rp1/Enpp1/Tnfrsf11b/Cd38/Nox4/Crocc/Bdkrb2/Ltbp3/Lpcat1/Rcn3/Iqcb1/Cldn5/Large1/Akt3/Ccn2/Def8/Bbs1/Abcb1a/Pdgfrb/Pfkm/F2r/Kcnh1	36
GO:0003272	endocardial cushion formation	BP	0.321	4.02e-06	5.86e-05	4.23	3.8e-05	Nog/Tbx2/Aplnr/Tbx3/Heyl/Snai1/Dchs1/Bmp7/Eng	9
GO:0043931	ossification involved in bone maturation	BP	0.321	4.02e-06	5.86e-05	4.23	3.8e-05	Ryr1/Plxnb1/Igf1/Thbs3/Enpp1/Adamts7/Dchs1/Xylt1/Fat4	9
GO:0061484	hematopoietic stem cell homeostasis	BP	0.321	4.02e-06	5.86e-05	4.23	3.8e-05	Gprasp2/Emcn/Crispld1/Myct1/Armcx1/Zfp251/Septin4/Fstl1/Glis2	9
GO:0030900	forebrain development	BP	0.103	4.18e-06	6.07e-05	4.22	3.94e-05	Gli1/Sema5a/Mdk/Lef1/Nog/Zeb2/Nrp1/Sema7a/Cdh2/Lrrk2/Dab1/Id4/Fut10/Cxcl12/Dnah5/Gli3/Plcb1/D16Ertd472e/Gdf7/Lrp2/Kif1a/Tsku/Tbx3/Dync2h1/Ndnf/Dclk2/Nin/Lhx6/Rtn4rl1/Dlc1/Nr2f1/Ttbk2/Fyn/Ptger3/Atp1a2/Fat4/Bbs1/Psen1/Bcl11b/Draxin/Numbl	41
GO:0045880	positive regulation of smoothened signaling pathway	BP	0.256	4.22e-06	6.12e-05	4.21	3.97e-05	Gli1/Ihh/Evc/Kif7/Gpc3/Cibar1/Armc9/Wnt9a/Rab34/Dync2h1/Dlg5	11
GO:0150116	regulation of cell-substrate junction organization	BP	0.203	4.25e-06	6.15e-05	4.21	3.98e-05	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Thy1/Ppm1f/Epha3/Limch1/Arhgap6/Dlc1/Mapre2/Enpp2	14
GO:0014812	muscle cell migration	BP	0.158	4.55e-06	6.52e-05	4.19	4.23e-05	Cyp1b1/Mdk/Igf1/Ddr2/Drd4/Tert/Myo5a/Mef2c/Has2/Adamts1/Postn/Enpp1/Nox4/Pcsk5/Net1/Plekho1/Pdgfrb/Grb10/Myc	19
GO:0072498	embryonic skeletal joint development	BP	0.438	4.55e-06	6.52e-05	4.19	4.23e-05	Ihh/Hoxd11/Nog/Hoxa11/Osr2/Osr1/Bmp7	7
GO:0010749	regulation of nitric oxide mediated signal transduction	BP	0.545	4.58e-06	6.52e-05	4.19	4.23e-05	Spink1/Cbs/Gucy1a2/Gucy1a1/Pde5a/Atp2b4	6
GO:0014832	urinary bladder smooth muscle contraction	BP	0.545	4.58e-06	6.52e-05	4.19	4.23e-05	Cacna1c/P2rx2/Kcnma1/Htr2a/Ptger3/Atp2b4	6
GO:0097104	postsynaptic membrane assembly	BP	0.545	4.58e-06	6.52e-05	4.19	4.23e-05	Nlgn1/Cdh2/Nlgn3/Magi2/Lrp4/Nlgn2	6
GO:0071560	cellular response to transforming growth factor beta stimulus	BP	0.124	4.58e-06	6.52e-05	4.19	4.23e-05	Cd109/Zeb2/Npnt/Nos3/Fermt2/Mef2c/Cdh5/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Ltbp3/Xcl1/Hipk2/Smad9/Nrros/Arrb2/Zfyve9/Fyn/Cldn5/Il17rd/Lats2/Cav1/Itga8/Nrep/Eng	28
GO:0014033	neural crest cell differentiation	BP	0.172	4.64e-06	6.6e-05	4.18	4.28e-05	Sema5a/Zeb2/Sema5b/Nrp1/Sema7a/Cdh2/Fn1/Ednrb/Mef2c/Edn3/Ednra/Sema3g/Kitl/Sema6a/Bmp7/Hand2/Twist1	17
GO:0014032	neural crest cell development	BP	0.18	4.76e-06	6.72e-05	4.17	4.36e-05	Sema5a/Zeb2/Sema5b/Nrp1/Sema7a/Cdh2/Fn1/Ednrb/Edn3/Ednra/Sema3g/Kitl/Sema6a/Bmp7/Hand2/Twist1	16
GO:1904427	positive regulation of calcium ion transmembrane transport	BP	0.18	4.76e-06	6.72e-05	4.17	4.36e-05	Cacna1c/Cacna2d1/Cxcr3/Ank2/Thy1/Aplnr/Cracr2a/Agtr1a/Ednra/Stac2/Asph/Pkd2/Gstm7/Sri/Cacnb4/F2r	16
GO:0051402	neuron apoptotic process	BP	0.11	4.87e-06	6.87e-05	4.16	4.45e-05	Ptprz1/Angpt1/Mdk/Kdr/Agap2/Nrp1/Tert/Bok/Mef2c/Pcdhgc3/Itga1/Coro1a/Scn2a/Grik2/Il27ra/Enpp1/Apoe/Kcnma1/Ndnf/Hipk2/Arrb1/Nfatc4/Epha7/Kcnip3/Arrb2/Bhlhb9/Fyn/Nlrp1b/Syngap1/Psen1/Nes/Cacna1a/Pcdhgc4/F2r/Draxin	35
GO:0060349	bone morphogenesis	BP	0.164	5e-06	7.02e-05	4.15	4.55e-05	Ihh/Mmp16/Sfrp2/Hoxd11/Thbs3/Cbs/Hoxa11/Mef2c/Osr2/Stc1/Has2/Gli3/Col13a1/Frem1/Enpp1/Ltbp3/Rab23/Twist1	18
GO:0061756	leukocyte adhesion to vascular endothelial cell	BP	0.231	5.01e-06	7.02e-05	4.15	4.55e-05	Mdk/Itga4/Chst2/Ets1/Itgb7/Icam1/Podxl2/Cxcl12/Sele/St3gal4/Spn/Jam2	12
GO:0035904	aorta development	BP	0.2	5.08e-06	7.1e-05	4.15	4.6e-05	Tbx2/Kif7/Fkbp10/Plxnd1/Lrp2/Prdm1/Aplnr/Enpp1/Ednra/Prickle1/Efemp2/Pdgfrb/Hey2/Eng	14
GO:0035115	embryonic forelimb morphogenesis	BP	0.278	5.15e-06	7.18e-05	4.14	4.66e-05	Cacna1c/Hoxd11/Hoxa11/Hoxd9/Osr2/Wnt9a/Tbx3/Hoxa9/Osr1/Twist1	10
GO:1903706	regulation of hemopoiesis	BP	0.102	5.34e-06	7.42e-05	4.13	4.81e-05	Ihh/Mdk/Lef1/Cd83/P4htm/Hcls1/Cd44/Ets1/Mef2c/Inpp4b/Pik3r6/Lrrc17/Gli3/Calca/Flt3/Loxl3/Zeb1/Prdm1/Cd1d1/Tnfrsf11b/Gpr171/Sox12/Zbtb46/Scin/Nckap1l/Kitl/Tal1/Tnfaip6/Hoxa9/Twist2/Rassf2/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Ptn/Il2rg/Il7r/Cd4/Myc	41
GO:0044782	cilium organization	BP	0.103	5.34e-06	7.42e-05	4.13	4.81e-05	Tub/Ccdc88a/Arl6/Dzip1l/Adamts16/Cibar1/Wdr35/Tmem237/Bbs7/Armc9/Dnah5/Zfp423/Ptpdc1/Ift57/Catip/Cplane1/Kctd17/Rp1/Rilpl1/Dync2h1/Crocc/Cfap410/Ttc26/Arl3/Cep19/Tmem231/Pkd2/Ttbk2/Iqcb1/Dnah7b/Rab23/Dzip1/Dync2li1/Lrrc49/Dnah1/Cep97/Bbs1/Atmin/Ift81/Septin6	40
GO:0032102	negative regulation of response to external stimulus	BP	0.102	5.67e-06	7.86e-05	4.1	5.09e-05	Hgf/Sema5a/Acod1/Mdk/Pla2g10/Cd109/Igf1/Sema5b/Aph1b/Phldb2/Tfpi/Abat/Nrp1/Cd44/Sema7a/Ets1/Foxf1/Serpine2/Fndc4/Cdh5/Prdm1/Nlgn3/Apoe/Havcr2/Sema3g/Cd200/Igf2/Pros1/Tnfaip6/Rtn4rl1/Neo1/Mapkbp1/Arrb2/Calcrl/Ptger3/Xylt1/Sema6a/Cd96/Nr1h3/Spn/Wfdc1	41
GO:1990138	neuron projection extension	BP	0.127	5.91e-06	8.17e-05	4.09	5.29e-05	Map2/Sema5a/Itga4/St8sia2/Sema5b/Cpne5/Nrp1/Sema7a/Fn1/Cxcl12/Edn3/Eif2ak4/Postn/Ndn/Nlgn3/Apoe/Ednra/Sema3g/Slc23a2/Cacng7/Sema6a/Ulk2/Nrn1/Cyfip2/Slit3/Draxin	26
GO:0097061	dendritic spine organization	BP	0.168	6.14e-06	8.47e-05	4.07	5.49e-05	Nlgn1/Lrrk2/Grin2b/Ppfia2/Dock10/Abi2/Kif1a/Nlgn3/Apoe/Caprin2/Bhlhb9/Fyn/Dlg4/Cux2/Ngef/Zmynd8/Zfp365	17
GO:0050806	positive regulation of synaptic transmission	BP	0.107	6.18e-06	8.49e-05	4.07	5.5e-05	Slc1a3/Gria4/Grik1/Nog/Nlgn1/Adra1a/Rims3/Stx1b/Grin2b/Serpine2/Shank2/Eif2ak4/Slc8a3/Syde1/Tshz3/Mme/Lama2/Grik2/Nlgn3/Enpp1/Nrgn/Apoe/Prrt1/Nsg1/Nfatc4/Cacng7/Cyp46a1/Arrb2/Ncs1/Mpp2/Dlg4/Slc4a8/Psen1/Ptn/Prkar1b/Nlgn2	36
GO:0048732	gland development	BP	0.0966	6.2e-06	8.5e-05	4.07	5.51e-05	Gli1/Stra6/Hgf/Ar/Mdk/Lef1/Agap2/Cyp7b1/Nog/Igf1/Tbx2/Nrp1/Cd44/Edaradd/Hoxd9/Areg/Mmp2/Foxf1/Id4/Serpine2/Tcf21/Gli3/Plxnd1/Gdf7/Msn/Cdkn1c/Tbx3/Hoxd3/Ednra/Igf2/Pkd1/Hoxa9/Ptch1/Stat5b/Pkd2/Asl/Psen1/Pdgfrb/Ptn/Cav1/Cacnb4/Edar/Bmp7/Hand2/Bcl11b/Irs1	46
GO:0003208	cardiac ventricle morphogenesis	BP	0.185	6.41e-06	8.74e-05	4.06	5.67e-05	Col11a1/Sfrp2/Nog/Mef2c/Foxf1/Lrp2/Cpe/Ccm2l/Ednra/Heyl/Myl3/Heg1/Hey2/Hand2/Eng	15
GO:0043279	response to alkaloid	BP	0.185	6.41e-06	8.74e-05	4.06	5.67e-05	Slc1a3/Ryr1/Abat/Slc8a1/Drd4/Htr1b/Ednra/Htr2a/Selenon/Dlg4/Gstm7/Smpd1/Bche/Myc/Irs1	15
GO:0071559	response to transforming growth factor beta	BP	0.122	6.42e-06	8.74e-05	4.06	5.67e-05	Cd109/Zeb2/Npnt/Nos3/Fermt2/Mef2c/Cdh5/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Ltbp3/Xcl1/Hipk2/Smad9/Nrros/Arrb2/Zfyve9/Fyn/Cldn5/Il17rd/Lats2/Cav1/Itga8/Nrep/Eng	28
GO:0051495	positive regulation of cytoskeleton organization	BP	0.127	6.46e-06	8.78e-05	4.06	5.69e-05	Sema5a/Wnt11/Evl/Ccdc88a/Nrp1/Fermt2/Wasf3/Pfn2/Icam1/Tek/Abi2/Ppm1f/Limch1/Nox4/Arhgef15/Ppm1e/Scin/Bin1/Nckap1l/Nin/Slain1/Ccn2/Cdc42ep5/Nes/Cav1/Plek	26
GO:0034767	positive regulation of ion transmembrane transport	BP	0.13	6.64e-06	9e-05	4.05	5.83e-05	Cacna1c/Tcaf1/Drd4/Cacna2d1/Myo5a/Cxcr3/Ank2/Edn3/Plcb1/Trpc6/Thy1/Aplnr/Nlgn3/Cracr2a/Agtr1a/Ednra/Stac2/Asph/Pkd2/Gstm7/Psen1/Abcb1a/Sri/Cacnb4/F2r	25
GO:0009954	proximal/distal pattern formation	BP	0.27	6.75e-06	9.12e-05	4.04	5.91e-05	Gli1/Hoxd10/Hoxd11/Hoxa11/Hoxd9/Hoxa10/Gli3/Hoxa9/Osr1/Lrp4	10
GO:0043523	regulation of neuron apoptotic process	BP	0.113	7e-06	9.44e-05	4.02	6.12e-05	Ptprz1/Angpt1/Mdk/Kdr/Agap2/Nrp1/Tert/Bok/Mef2c/Pcdhgc3/Itga1/Coro1a/Grik2/Il27ra/Apoe/Kcnma1/Ndnf/Hipk2/Arrb1/Nfatc4/Epha7/Kcnip3/Arrb2/Bhlhb9/Fyn/Syngap1/Psen1/Nes/Cacna1a/Pcdhgc4/F2r/Draxin	32
GO:0150115	cell-substrate junction organization	BP	0.167	7.04e-06	9.48e-05	4.02	6.14e-05	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Fn1/Thsd1/Tek/Thy1/Ppm1f/Epha3/Limch1/Arhgap6/Dlc1/Mapre2/Itgb4/Enpp2	17
GO:0051090	regulation of DNA-binding transcription factor activity	BP	0.0986	7.44e-06	9.98e-05	4	6.47e-05	Gli1/Ndp/Cyp1b1/4930447C04Rik/Acod1/Ar/Pla2g10/Ddr2/Eda2r/Hcls1/Id3/Icam1/Prkd1/Gli3/Eif2ak4/Plpp3/Ndn/Kit/Cth/Enpp1/Havcr2/Heyl/Cd200/Zc4h2/Pkd1/Hipk2/Rps6ka5/Arrb1/Foxs1/Arrb2/Ptch1/Pkd2/Cd84/Nwd1/Fzd2/Sri/Glis2/Cav1/Commd7/Ror1/Hand2/Twist1/Zfp932	43
GO:0051279	regulation of release of sequestered calcium ion into cytosol	BP	0.183	7.5e-06	1e-04	4	6.5e-05	Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Selenon/Asph/Pkd2/Gstm7/Sri/F2r	15
GO:0035088	establishment or maintenance of apical/basal cell polarity	BP	0.222	7.61e-06	0.000101	4	6.55e-05	Wnt11/Lrrc7/Foxf1/Myo9a/Msn/Dlg2/Prickle2/Lin7a/Sh3bp1/Pard3b/Dlg5/Pdcd6ip	12
GO:0061245	establishment or maintenance of bipolar cell polarity	BP	0.222	7.61e-06	0.000101	4	6.55e-05	Wnt11/Lrrc7/Foxf1/Myo9a/Msn/Dlg2/Prickle2/Lin7a/Sh3bp1/Pard3b/Dlg5/Pdcd6ip	12
GO:0070977	bone maturation	BP	0.3	7.63e-06	0.000101	4	6.55e-05	Ryr1/Plxnb1/Igf1/Thbs3/Enpp1/Adamts7/Dchs1/Xylt1/Fat4	9
GO:0140058	neuron projection arborization	BP	0.3	7.63e-06	0.000101	4	6.55e-05	Nlgn1/Nrp1/Lrrk2/Myo9a/Lrp2/Dlg4/Ptn/Ntng1/Zfp365	9
GO:1903131	mononuclear cell differentiation	BP	0.0949	7.88e-06	0.000104	3.98	6.75e-05	Ihh/Mdk/Lef1/Cd83/Itm2a/Cd44/Il11ra1/Mef2c/Itk/Cd3g/Pik3r6/Gli3/Dock2/Flt3/Lfng/Tnfsf13b/Loxl3/Dock10/Zeb1/Prdm1/Jag2/Cd1d1/Kit/H2-Ab1/Enpp1/Cracr2a/Sox12/Irf8/Zbtb46/Nckap1l/Satb1/Hdac9/Stat5b/H2-Aa/Gimap5/Mfng/Zap70/Gimap3/Psen1/Il2rg/Batf/Spn/Ly9/Il7r/Cd4/Bcl11b/Myc	47
GO:0033002	muscle cell proliferation	BP	0.116	8.33e-06	0.00011	3.96	7.12e-05	Gli1/Angpt1/Vipr2/Nog/Igf1/Ddr2/Tbx2/Nos3/Npr3/Drd4/Tert/Mmp2/Mef2c/Cdh13/Adamts1/Htr1b/Enpp1/Apoe/Rgs5/Ednra/Selenon/Stat5b/Irak4/Calcrl/Efemp2/Apln/Pdgfrb/Cav1/Hey2/Myc	30
GO:0061512	protein localization to cilium	BP	0.192	8.49e-06	0.000112	3.95	7.24e-05	Tub/Ccdc88a/Arl6/Dzip1l/Wdr35/Zfp423/Cplane1/Dync2h1/Crocc/Ttc26/Arl3/Dzip1/Bbs1/Rabep1	14
GO:0001894	tissue homeostasis	BP	0.112	8.71e-06	0.000114	3.94	7.41e-05	Tex15/Ihh/Angpt1/Kdr/Col14a1/Tub/Nos3/Calca/Flt3/Pth1r/Pbld2/Coro1a/Ldb2/Rp1/Enpp1/Tnfrsf11b/Cd38/Nox4/Crocc/Bdkrb2/Ltbp3/Lpcat1/Rcn3/Iqcb1/Cldn5/Akt3/Ccn2/Def8/Bbs1/Abcb1a/Pdgfrb/F2r	32
GO:0019722	calcium-mediated signaling	BP	0.128	8.74e-06	0.000114	3.94	7.42e-05	Sgcd/Kdr/Nr5a2/Igf1/Slc8a1/Drd4/Lrrk2/Ednrb/Slc24a4/Cxcr3/Cdh13/Ptgfr/Adgrl1/Ank2/Itgal/Agtr1a/Cmya5/Nfatc4/Xcr1/Atp2b4/Zap70/Lat/Rcan3/Cd4/Tbc1d10c	25
GO:0097106	postsynaptic density organization	BP	0.263	8.77e-06	0.000115	3.94	7.42e-05	Ptprd/Nlgn1/Cdh2/Lrrc4b/Nptx1/Shank2/Slitrk3/Syngap1/Zmynd8/Nlgn2	10
GO:0007219	Notch signaling pathway	BP	0.13	8.95e-06	0.000117	3.93	7.56e-05	Tbx2/Aph1b/Cdh6/Ptp4a3/Zfp423/Postn/Lfng/Jag2/Kit/Hoxd3/Heyl/Snai1/Arrb1/Dtx3/Tspan5/Egfl7/Mfng/Fat4/Psen1/Bend6/Maml3/Bmp7/Hey2/S1pr3	24
GO:0014911	positive regulation of smooth muscle cell migration	BP	0.203	9.18e-06	0.000118	3.93	7.67e-05	Cyp1b1/Mdk/Igf1/Ddr2/Tert/Myo5a/Has2/Adamts1/Postn/Nox4/Pcsk5/Pdgfrb/Myc	13
GO:0033344	cholesterol efflux	BP	0.203	9.18e-06	0.000118	3.93	7.67e-05	Apob/Pla2g10/Soat1/Pltp/Tsku/Apoe/Abca5/Ptch1/Abcg1/Abca8b/Cav1/Nr1h3/Abcg4	13
GO:0051893	regulation of focal adhesion assembly	BP	0.203	9.18e-06	0.000118	3.93	7.67e-05	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Thy1/Ppm1f/Epha3/Limch1/Arhgap6/Dlc1/Enpp2	13
GO:0090109	regulation of cell-substrate junction assembly	BP	0.203	9.18e-06	0.000118	3.93	7.67e-05	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Thy1/Ppm1f/Epha3/Limch1/Arhgap6/Dlc1/Enpp2	13
GO:0030510	regulation of BMP signaling pathway	BP	0.163	9.21e-06	0.000118	3.93	7.67e-05	Sfrp2/Kdr/Nog/Rnf165/Fst/Gpc3/Zfp423/Cdh5/Lrp2/Hipk2/Kcp/Tnfaip6/Neo1/Fstl1/Cav1/Tmprss6/Eng	17
GO:0070167	regulation of biomineral tissue development	BP	0.163	9.21e-06	0.000118	3.93	7.67e-05	Wnt6/Ddr2/Pkdcc/Slc8a1/Nos3/Mef2c/Osr2/Nell1/Mgp/Enpp1/Ltbp3/Osr1/Ptn/Bmp7/Hey2/Ank/Twist1	17
GO:0060271	cilium assembly	BP	0.104	9.28e-06	0.000119	3.92	7.71e-05	Ccdc88a/Arl6/Dzip1l/Adamts16/Cibar1/Wdr35/Tmem237/Bbs7/Armc9/Dnah5/Zfp423/Ptpdc1/Ift57/Cplane1/Kctd17/Rp1/Rilpl1/Dync2h1/Crocc/Cfap410/Ttc26/Arl3/Cep19/Tmem231/Ttbk2/Iqcb1/Dnah7b/Rab23/Dzip1/Dync2li1/Lrrc49/Dnah1/Cep97/Bbs1/Atmin/Ift81/Septin6	37
GO:0046634	regulation of alpha-beta T cell activation	BP	0.157	9.48e-06	0.000121	3.92	7.86e-05	Ihh/Cd83/Cd44/Mapk8ip1/Gli3/Loxl3/Prdm1/Cd1d1/H2-Ab1/Btla/Nckap1l/Xcl1/Gimap5/Zap70/Gimap3/Il12rb1/Il2rg/Rasal3	18
GO:0009952	anterior/posterior pattern specification	BP	0.119	9.67e-06	0.000123	3.91	8e-05	Sfrp2/Lef1/Hoxd10/Hoxd11/Nog/Zeb2/Hoxa11/Gpc3/Hoxd9/Hoxa10/Foxf1/Hoxd8/Hoxd4/Tshz1/Gdf11/Gli3/Lfng/Tbx3/Hoxd3/Heyl/Hipk2/Pcsk5/Hoxa9/Osr1/Ets2/Psen1/Hipk1/Hey2	28
GO:0030203	glycosaminoglycan metabolic process	BP	0.17	9.86e-06	0.000126	3.9	8.14e-05	Angpt1/Cd44/Spock2/Ednrb/Has2/Egflam/Mamdc2/Chst1/Ednra/Ndnf/Tnfaip6/Bgn/Dse/Habp4/Xylt1/Pdgfrb	16
GO:0051017	actin filament bundle assembly	BP	0.133	9.95e-06	0.000126	3.9	8.19e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Aif1l/Pfn2/Ppm1f/Limch1/Arhgap6/Nox4/Arhgef15/Tmeff2/Ppm1e/Arrb1/Dlc1/Arhgap28/Ccn2/Dpysl3/Shroom1/Plek	23
GO:2000300	regulation of synaptic vesicle exocytosis	BP	0.179	1.02e-05	0.000129	3.89	8.37e-05	Nlgn1/Adra1a/Rims3/P2rx2/Drd4/Lrrk2/Pfn2/Ppfia2/Htr1b/Htr2a/Ncs1/Slc4a8/Nrn1/Cacnb4/Kcnh1	15
GO:0002026	regulation of the force of heart contraction	BP	0.29	1.03e-05	0.00013	3.89	8.4e-05	Adra1a/Slc8a1/Nos3/Myl3/Pde5a/Atp2b4/Apln/Atp1a2/Cav1	9
GO:0060317	cardiac epithelial to mesenchymal transition	BP	0.29	1.03e-05	0.00013	3.89	8.4e-05	Nog/Erg/Has2/Tbx3/Heyl/Snai1/Hey2/Twist1/Eng	9
GO:2000352	negative regulation of endothelial cell apoptotic process	BP	0.29	1.03e-05	0.00013	3.89	8.4e-05	Sema5a/Angpt1/Kdr/Tert/Icam1/Tek/Cdh5/Ndnf/Angptl4	9
GO:0008154	actin polymerization or depolymerization	BP	0.126	1.04e-05	0.000131	3.88	8.51e-05	Kank4/Sema5a/Evl/Hcls1/Tmod2/Pfn2/Icam1/Mical1/Abi2/Catip/Coro1a/Esam/Sh3bp1/Daam2/Pecam1/Scin/Bin1/Nckap1l/Arhgap28/Wipf1/Cdc42ep5/Plekhh2/Cyfip2/Plek/Pstpip1	25
GO:0007628	adult walking behavior	BP	0.234	1.07e-05	0.000134	3.87	8.65e-05	Efnb3/Cacna1c/Scn1a/Dab1/Glrb/Enpp1/Kcnma1/Hipk2/Arrb2/Cacna1a/Cacnb4	11
GO:0043616	keratinocyte proliferation	BP	0.234	1.07e-05	0.000134	3.87	8.65e-05	Mdk/Cd109/Fst/Prkd1/Cdh13/Has2/Stxbp4/Klf9/Twist2/Ptch1/Bcl11b	11
GO:0050974	detection of mechanical stimulus involved in sensory perception	BP	0.234	1.07e-05	0.000134	3.87	8.65e-05	Col11a1/Igf1/Scn1a/Grin2b/Serpine2/Cxcl12/Kit/Htr2a/Fyn/Piezo2/Myc	11
GO:0043534	blood vessel endothelial cell migration	BP	0.155	1.07e-05	0.000134	3.87	8.65e-05	Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Mef2c/Prkd1/Vash1/Cdh5/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Hdac9/Akt3/Atp2b4	18
GO:0007179	transforming growth factor beta receptor signaling pathway	BP	0.129	1.08e-05	0.000134	3.87	8.67e-05	Cd109/Zeb2/Npnt/Fermt2/Cdh5/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Ltbp3/Hipk2/Smad9/Nrros/Arrb2/Zfyve9/Cldn5/Il17rd/Lats2/Cav1/Itga8/Nrep/Eng	24
GO:0010594	regulation of endothelial cell migration	BP	0.132	1.09e-05	0.000136	3.87	8.79e-05	Sema5a/Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Mef2c/Prkd1/Stc1/Tek/Vash1/Ptprm/Plpp3/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Hdac9/Akt3/Atp2b4/Adgra2	23
GO:0060999	positive regulation of dendritic spine development	BP	0.2	1.1e-05	0.000136	3.87	8.8e-05	Nlgn1/D16Ertd472e/Nlgn3/Apoe/Caprin2/Bhlhb9/Cux2/Palm/Dlg5/Psen1/Zmynd8/Camk1/Nlgn2	13
GO:0045879	negative regulation of smoothened signaling pathway	BP	0.256	1.13e-05	0.000139	3.86	9.02e-05	Gli1/Hhip/Kif7/Gpc3/Serpine2/Gli3/Gpr161/Enpp1/Ptch1/Glis2	10
GO:0043536	positive regulation of blood vessel endothelial cell migration	BP	0.214	1.13e-05	0.000139	3.86	9.03e-05	Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Prkd1/Jcad/Vegfc/Igf2/Hdac9/Akt3	12
GO:0048864	stem cell development	BP	0.168	1.13e-05	0.000139	3.86	9.03e-05	Sema5a/Zeb2/Sema5b/Nrp1/Sema7a/Cdh2/Fn1/Ednrb/Edn3/Ednra/Sema3g/Kitl/Sema6a/Bmp7/Hand2/Twist1	16
GO:0051588	regulation of neurotransmitter transport	BP	0.144	1.14e-05	0.000139	3.86	9.03e-05	Nlgn1/Adra1a/Rims3/Stx1b/P2rx2/Drd4/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Htr1b/Kcnc4/Htr2a/Ncs1/Slc4a8/Nrn1/Cacna1a/Cacnb4/Kcnh1	20
GO:0055123	digestive system development	BP	0.144	1.14e-05	0.000139	3.86	9.03e-05	Stra6/Ihh/Sfrp2/Clmp/Igf1/Pkdcc/Tbx2/Ednrb/Foxf1/Tcf21/Gli3/Prdm1/Kit/Cdkn1c/Igf2/Pcsk5/Dchs1/Fat4/Stx2/Dact1	20
GO:0097091	synaptic vesicle clustering	BP	0.389	1.16e-05	0.000142	3.85	9.2e-05	Syn2/Nlgn1/Cdh2/Nlgn3/Magi2/Pcdh17/Nlgn2	7
GO:0042129	regulation of T cell proliferation	BP	0.128	1.18e-05	0.000144	3.84	9.31e-05	Ihh/Igf1/Cd44/Mapk8ip1/Tnfsf13b/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Havcr2/Igf2/Nckap1l/Xcl1/Stat5b/Pde5a/H2-Aa/Dlg5/Zap70/Il12rb1/Spn/Cd4/Rasal3	24
GO:0014909	smooth muscle cell migration	BP	0.16	1.2e-05	0.000145	3.84	9.39e-05	Cyp1b1/Mdk/Igf1/Ddr2/Drd4/Tert/Myo5a/Mef2c/Has2/Adamts1/Postn/Enpp1/Nox4/Pcsk5/Pdgfrb/Grb10/Myc	17
GO:0048659	smooth muscle cell proliferation	BP	0.128	1.29e-05	0.000156	3.81	0.000101	Vipr2/Igf1/Ddr2/Nos3/Npr3/Drd4/Tert/Mmp2/Mef2c/Cdh13/Adamts1/Htr1b/Enpp1/Apoe/Rgs5/Ednra/Stat5b/Irak4/Calcrl/Efemp2/Apln/Pdgfrb/Cav1/Myc	24
GO:0007044	cell-substrate junction assembly	BP	0.167	1.3e-05	0.000157	3.81	0.000101	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Fn1/Thsd1/Tek/Thy1/Ppm1f/Epha3/Limch1/Arhgap6/Dlc1/Itgb4/Enpp2	16
GO:0061572	actin filament bundle organization	BP	0.131	1.32e-05	0.000159	3.8	0.000103	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Aif1l/Pfn2/Ppm1f/Limch1/Arhgap6/Nox4/Arhgef15/Tmeff2/Ppm1e/Arrb1/Dlc1/Arhgap28/Ccn2/Dpysl3/Shroom1/Plek	23
GO:0001941	postsynaptic membrane organization	BP	0.229	1.33e-05	0.000159	3.8	0.000103	Nlgn1/Cdh2/Glrb/Nlgn3/Apoe/Magi2/Dlg4/Ptn/Zmynd8/Lrp4/Nlgn2	11
GO:0003179	heart valve morphogenesis	BP	0.229	1.33e-05	0.000159	3.8	0.000103	Stra6/Nos3/Mef2c/Erg/Emilin1/Tie1/Heyl/Dchs1/Hey2/Slit3/Twist1	11
GO:0003382	epithelial cell morphogenesis	BP	0.229	1.33e-05	0.000159	3.8	0.000103	Ihh/Ar/Stc1/Palld/Rilpl1/Pecam1/Col15a1/Heg1/Arhgef26/Col18a1/Bcl11b	11
GO:0046632	alpha-beta T cell differentiation	BP	0.147	1.33e-05	0.000159	3.8	0.000103	Ihh/Lef1/Cd83/Itk/Gli3/Loxl3/Prdm1/Cd1d1/Cracr2a/Nckap1l/Satb1/Gimap5/Zap70/Gimap3/Il2rg/Batf/Spn/Ly9/Bcl11b	19
GO:0019229	regulation of vasoconstriction	BP	0.174	1.37e-05	0.000162	3.79	0.000105	Cacna1c/Adra1a/Mmp2/Icam1/Wdr35/Edn3/Cd38/Agtr1a/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1/F2r	15
GO:0098703	calcium ion import across plasma membrane	BP	0.281	1.37e-05	0.000162	3.79	0.000105	Cacna1c/Slc8a1/Slc24a4/Cacna1e/Slc8a3/Nalf1/Agtr1a/Fyn/Cacna1a	9
GO:0061383	trabecula morphogenesis	BP	0.211	1.37e-05	0.000162	3.79	0.000105	Plxnb1/Nog/Thbs3/Mmp2/Tek/Adamts1/Ccm2l/Enpp1/Heg1/Bmp7/Hey2/Eng	12
GO:0030098	lymphocyte differentiation	BP	0.0962	1.37e-05	0.000162	3.79	0.000105	Ihh/Mdk/Lef1/Cd83/Itm2a/Cd44/Il11ra1/Itk/Cd3g/Pik3r6/Gli3/Dock2/Flt3/Lfng/Tnfsf13b/Loxl3/Dock10/Zeb1/Prdm1/Jag2/Cd1d1/Kit/H2-Ab1/Enpp1/Cracr2a/Sox12/Irf8/Nckap1l/Satb1/Hdac9/Stat5b/H2-Aa/Gimap5/Mfng/Zap70/Gimap3/Il2rg/Batf/Spn/Ly9/Il7r/Cd4/Bcl11b	43
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	BP	0.119	1.43e-05	0.000168	3.77	0.000109	Vipr2/Adra1a/Adgrl4/Npr3/Drd4/Gnai1/Adcy3/Cxcr3/Akap12/Ptgfr/Adgrl1/Calca/Htr1b/Pth1r/Adcy4/Adcy7/Gpr161/Ednra/Adcyap1r1/Calcrl/Gnaz/Ptger3/Palm/Atp2b4/Gabbr1/S1pr3/Ptger2	27
GO:0048265	response to pain	BP	0.25	1.44e-05	0.000169	3.77	0.00011	Grik1/Slc6a2/P2rx2/Ednrb/Grin2b/Cacna1e/Calca/Kcnip3/Vwa1/Cacna1a	10
GO:0002695	negative regulation of leukocyte activation	BP	0.124	1.48e-05	0.000173	3.76	0.000112	Ihh/Mdk/Cd44/Foxf1/Gli3/Flt3/Loxl3/Prdm1/H2-Ab1/Btla/Havcr2/Cd200/Nckap1l/Pde5a/Cd84/Fgr/H2-Aa/Dlg5/Gimap5/Gimap3/Clnk/Nr1h3/Spn/Tbc1d10c/Lax1	25
GO:0045666	positive regulation of neuron differentiation	BP	0.151	1.54e-05	0.00018	3.75	0.000116	Fez1/Rgs6/Dab1/Mef2c/Cxcl12/Gprc5b/Trpc6/Gdf7/Tgif2/Zeb1/Mmd/Tcf4/Hoxd3/Heyl/Zc4h2/Nin/Bend6/Bmp7	18
GO:0060272	embryonic skeletal joint morphogenesis	BP	0.462	1.56e-05	0.000182	3.74	0.000118	Hoxd11/Nog/Hoxa11/Osr2/Osr1/Bmp7	6
GO:0097090	presynaptic membrane organization	BP	0.462	1.56e-05	0.000182	3.74	0.000118	Ptprd/Nlgn1/Nlgn3/Apoe/Lrp4/Nlgn2	6
GO:0048167	regulation of synaptic plasticity	BP	0.101	1.61e-05	0.000187	3.73	0.000121	Grik1/Kdr/Jph4/Nog/Grid2ip/Nlgn1/Rims3/Mef2c/Grin2b/Serpine2/Shank2/Eif2ak4/Slc8a3/Tshz3/Kit/Mme/Grik2/Nlgn3/Enpp1/Nrgn/Sorcs2/Cd38/Apoe/Prrt1/Syt7/Prrt2/Nsg1/Nfatc4/Cyp46a1/Mpp2/Erc2/Dlg4/Syngap1/Brsk1/Psen1/Ptn/Cpeb1/Prkar1b	38
GO:0045761	regulation of adenylate cyclase activity	BP	0.224	1.64e-05	0.00019	3.72	0.000123	Cacna1c/Vipr2/Npr3/Adcy3/Calca/Adcy4/Adcy7/Cap2/Palm/Gng7/Gabbr1	11
GO:0051496	positive regulation of stress fiber assembly	BP	0.207	1.66e-05	0.000191	3.72	0.000124	Wnt11/Evl/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Ppm1e/Ccn2	12
GO:0032535	regulation of cellular component size	BP	0.0992	1.69e-05	0.000194	3.71	0.000126	Kank4/Map2/Sema5a/Evl/Sema5b/Slc12a8/Nrp1/Hcls1/Sema7a/Tmod2/Fn1/Pfn2/Icam1/Cxcl12/Coro1a/Esam/Sh3bp1/Apoe/Kcnma1/Sema3g/Daam2/Pecam1/Scin/Bin1/Nckap1l/Epha7/Slc12a4/Arhgap28/Aqp11/Akt3/Cdc42ep5/Sema6a/Ulk2/Plekhh2/Cyfip2/C1qtnf9/Il7r/Plek/Draxin	39
GO:0051648	vesicle localization	BP	0.126	1.69e-05	0.000194	3.71	0.000126	Syn2/Map2/Itga4/Nlgn1/Sec16b/Cdh2/Lrrk2/Myo5a/Ppfia2/Kif1a/Lin7a/Nlgn3/Magi2/5730455P16Rik/Pcdh17/Myo1f/Cep19/Arfgap3/Psen1/Rab27a/Map4k2/Pdcd6ip/Kif5a/Nlgn2	24
GO:0030148	sphingolipid biosynthetic process	BP	0.163	1.7e-05	0.000195	3.71	0.000126	St8sia2/St8sia4/Agk/Elovl4/Cerkl/Sptlc3/Cers4/St3gal2/St6galnac4/Degs2/St8sia6/Abca8b/St6galnac6/B3gnt5/Smpd1/Hacd1	16
GO:0070252	actin-mediated cell contraction	BP	0.163	1.7e-05	0.000195	3.71	0.000126	Cacna1c/Sgcd/Kcnd3/Scn4b/Scn1a/Cacna2d1/Stc1/Ank2/Limch1/Bin1/Epdr1/Cacna1h/Ptger3/Atp1a2/Sri/Cav1	16
GO:0043547	positive regulation of GTPase activity	BP	0.113	1.79e-05	0.000204	3.69	0.000132	Wnt11/Plxnb1/Rgs6/Fermt2/Rgs16/Rasgrp3/Garnl3/Arhgap45/Icam1/Arhgap25/Rasgrp2/Myo9a/Thy1/Dock10/Sh3bp1/Arhgap6/Arhgef15/Bin1/Arap3/Xcl1/Arhgef26/Net1/Gnb5/Ngef/Mapre2/Iqsec3/F2r/Sipa1/Tbc1d10c	29
GO:0150117	positive regulation of cell-substrate junction organization	BP	0.273	1.8e-05	0.000205	3.69	0.000133	Kdr/Nrp1/Fermt2/Col16a1/Tek/Thy1/Ppm1f/Mapre2/Enpp2	9
GO:1902656	calcium ion import into cytosol	BP	0.273	1.8e-05	0.000205	3.69	0.000133	Cacna1c/Slc8a1/Slc24a4/Cacna1e/Slc8a3/Nalf1/Agtr1a/Fyn/Cacna1a	9
GO:0036293	response to decreased oxygen levels	BP	0.115	1.81e-05	0.000205	3.69	0.000133	Kcnk3/Kcnd2/Kdr/Ryr1/Ddah1/Abat/Slc8a1/Cbs/P2rx2/Pygm/Tert/Mmp2/Grin2b/Tek/Slc8a3/Scn2a/Vegfc/Cd38/Kcnma1/Ednra/Ndnf/Cav1/Cpeb1/Pld2/Hif3a/Myc/Twist1/Eng	28
GO:2000463	positive regulation of excitatory postsynaptic potential	BP	0.244	1.82e-05	0.000206	3.69	0.000134	Nlgn1/Stx1b/Drd4/Grin2b/Tbc1d24/Nlgn3/Dlg4/Cux2/Prkar1b/Nlgn2	10
GO:0032233	positive regulation of actin filament bundle assembly	BP	0.191	1.83e-05	0.000207	3.68	0.000134	Wnt11/Evl/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Ppm1e/Ccn2/Plek	13
GO:0006665	sphingolipid metabolic process	BP	0.139	1.94e-05	0.000219	3.66	0.000142	St8sia2/St8sia4/Agk/Elovl4/Cerkl/Sptlc3/Cers4/St3gal2/Plpp3/St6galnac4/Kit/Degs2/St8sia6/Abca8b/Plpp1/St6galnac6/B3gnt5/Smpd1/Hacd1/Enpp2	20
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	BP	0.149	1.94e-05	0.000219	3.66	0.000142	Cd109/Zeb2/Npnt/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Hipk2/Nrros/Zfyve9/Il17rd/Lats2/Cav1/Itga8/Nrep/Eng	18
GO:0016525	negative regulation of angiogenesis	BP	0.155	1.97e-05	0.000221	3.66	0.000143	Hhip/Cxcr3/Tek/Adamts1/Vash1/Ptprm/Minar1/Emilin1/Ecscr/Tcf4/Tie1/Cldn5/Atp2b4/Sema6a/Ptn/Stab1/Fbln5	17
GO:0034446	substrate adhesion-dependent cell spreading	BP	0.155	1.97e-05	0.000221	3.66	0.000143	Mdk/Itga4/Nrp1/Lamc3/Fermt2/Itgb7/Fn1/Tek/Has2/Postn/Tmeff2/Parvg/Parvb/Net1/Ntng1/Itga8/Enpp2	17
GO:0031279	regulation of cyclase activity	BP	0.203	1.99e-05	0.000223	3.65	0.000144	Cacna1c/Vipr2/Nos3/Npr3/Adcy3/Calca/Adcy4/Adcy7/Cap2/Palm/Gng7/Gabbr1	12
GO:0034332	adherens junction organization	BP	0.22	2.01e-05	0.000224	3.65	0.000145	Fermt2/Cdh6/Jam3/Cdh10/Cdh5/Abi2/Cdh11/Dchs1/Dlg5/Hipk1/Numbl	11
GO:0090659	walking behavior	BP	0.22	2.01e-05	0.000224	3.65	0.000145	Efnb3/Cacna1c/Scn1a/Dab1/Glrb/Enpp1/Kcnma1/Hipk2/Arrb2/Cacna1a/Cacnb4	11
GO:0060041	retina development in camera-type eye	BP	0.127	2.09e-05	0.000233	3.63	0.000151	Ndp/Ihh/Cyp1b1/Sdk2/Tub/Celf4/Nrp1/Lamc3/Arl6/Obsl1/Ptprm/Thy1/Tgif2/Rp1/Arhgef15/Lpcat1/Hipk2/Rorb/Nphp1/Fat3/Pdgfrb/Ptn/Hipk1	23
GO:0038084	vascular endothelial growth factor signaling pathway	BP	0.238	2.29e-05	0.000254	3.59	0.000165	Kdr/Nrp1/Ptp4a3/Prkd1/Jcad/Vegfc/Tcf4/Adgra2/Sema6a/Pdgfrb	10
GO:0048799	animal organ maturation	BP	0.265	2.35e-05	0.00026	3.58	0.000169	Ryr1/Plxnb1/Igf1/Thbs3/Enpp1/Adamts7/Dchs1/Xylt1/Fat4	9
GO:0002027	regulation of heart rate	BP	0.152	2.51e-05	0.000276	3.56	0.000179	Cacna1c/Kcnd3/Adra1a/Slc8a1/Scn4b/Cacna2d1/Ednrb/Cacna1e/Ank2/Edn3/Calca/Ednra/Bin1/Apln/Sri/Cav1/Hey2	17
GO:2000181	negative regulation of blood vessel morphogenesis	BP	0.152	2.51e-05	0.000276	3.56	0.000179	Hhip/Cxcr3/Tek/Adamts1/Vash1/Ptprm/Minar1/Emilin1/Ecscr/Tcf4/Tie1/Cldn5/Atp2b4/Sema6a/Ptn/Stab1/Fbln5	17
GO:0086003	cardiac muscle cell contraction	BP	0.186	2.54e-05	0.000278	3.56	0.00018	Cacna1c/Sgcd/Kcnd3/Scn4b/Scn1a/Cacna2d1/Stc1/Ank2/Bin1/Cacna1h/Atp1a2/Sri/Cav1	13
GO:0002031	G protein-coupled receptor internalization	BP	0.35	2.6e-05	0.000285	3.55	0.000185	Calca/Htr1b/Arrb1/Arrb2/Ptger3/Apln/Pld2	7
GO:0002064	epithelial cell development	BP	0.115	2.67e-05	0.000291	3.54	0.000189	Ihh/Ar/Cdh2/Ednrb/Icam1/Stc1/Plcb1/Cdh5/Msn/Prdm1/Abi2/Palld/Ppp1r16b/Robo4/Rilpl1/Ednra/Pecam1/Col15a1/Heg1/Arhgef26/Cldn5/Abcb1a/Akap11/Col18a1/Cldn1/Bcl11b/S1pr3	27
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	BP	0.145	2.72e-05	0.000297	3.53	0.000192	Cd109/Zeb2/Npnt/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Hipk2/Nrros/Zfyve9/Il17rd/Lats2/Cav1/Itga8/Nrep/Eng	18
GO:0035023	regulation of Rho protein signal transduction	BP	0.165	2.75e-05	0.000299	3.52	0.000194	Adra1a/Nrp1/Cdh2/Lpar4/Arhgef25/Eps8l1/Apoe/Rasip1/Arap3/Arrb1/Heg1/Dlc1/Net1/Pdgfrb/F2r	15
GO:0048638	regulation of developmental growth	BP	0.097	2.81e-05	0.000305	3.52	0.000198	Gli1/Map2/Sema5a/Ar/Cacna1c/Col14a1/H19/Nog/Igf1/Tbx2/Sema5b/Cpne5/Nrp1/Nkd1/Acacb/Sema7a/Fn1/Mef2c/Cxcl12/Hopx/Flvcr1/Gamt/Plcb1/Flt3/Apoe/Sema3g/Igf2/Slc23a2/Foxs1/Epha7/Cacng7/Ptch1/Stat5b/Pi16/Lats2/Sema6a/Ulk2/Hey2/Draxin	39
GO:1901343	negative regulation of vasculature development	BP	0.15	2.82e-05	0.000306	3.51	0.000198	Hhip/Cxcr3/Tek/Adamts1/Vash1/Ptprm/Minar1/Emilin1/Ecscr/Tcf4/Tie1/Cldn5/Atp2b4/Sema6a/Ptn/Stab1/Fbln5	17
GO:0010874	regulation of cholesterol efflux	BP	0.233	2.86e-05	0.000308	3.51	2e-04	Pla2g10/Pltp/Apoe/Abca5/Ptch1/Abcg1/Abca8b/Cav1/Nr1h3/Abcg4	10
GO:0085029	extracellular matrix assembly	BP	0.233	2.86e-05	0.000308	3.51	2e-04	Ihh/Phldb2/Fkbp10/Has2/Emilin1/Tie1/Ltbp3/Efemp2/Ntng1/Fbln5	10
GO:0014706	striated muscle tissue development	BP	0.107	2.94e-05	0.000316	3.5	0.000205	Gli1/Col11a1/AW551984/Angpt1/Lef1/Sgcd/Col14a1/Nog/Igf1/Tbx2/Adra1a/Slc8a1/Mef2c/Lrp2/Ccm2l/Nox4/Tbx3/Gjc1/Ednra/Myl3/Hdac9/Heg1/Arrb2/Pi16/Sgcb/Pdgfrb/Bmp7/Hey2/Hand2/Twist1/Eng	31
GO:0061005	cell differentiation involved in kidney development	BP	0.212	2.98e-05	0.00032	3.49	0.000208	Ptpro/Ednrb/Mef2c/Tcf21/Gli3/Tshz3/Ednra/Ptch1/Osr1/Fat4/Glis2	11
GO:1904738	vascular associated smooth muscle cell migration	BP	0.257	3.03e-05	0.000325	3.49	0.000211	Ddr2/Drd4/Tert/Myo5a/Mef2c/Adamts1/Enpp1/Pcsk5/Grb10	9
GO:0021915	neural tube development	BP	0.121	3.07e-05	0.000329	3.48	0.000213	Sfrp2/Nog/Zeb2/Dzip1l/Sall2/Gli3/Ift57/Gdf7/Lrp2/Cecr2/Gpr161/Phgdh/Prickle1/Ipmk/Dlc1/Ptch1/Dchs1/Ttbk2/Rab23/Fzd2/Psen1/Dact1/Bmp7/Twist1	24
GO:0050905	neuromuscular process	BP	0.121	3.07e-05	0.000329	3.48	0.000213	Ankfn1/Stra6/Slc1a3/Hoxd10/Jph4/Aph1b/Scn1a/Myo5a/Grin2b/Slc8a3/Tshz3/Glrb/Nlgn3/Npas3/Prrt2/Kcnma1/Ednra/Hipk2/Foxs1/Stac2/Dlg4/Cacna1a/Kcnh1/Nlgn2	24
GO:0006643	membrane lipid metabolic process	BP	0.124	3.25e-05	0.000346	3.46	0.000224	Cyp1b1/St8sia2/St8sia4/Agk/Elovl4/Cerkl/Sptlc3/Cers4/St3gal2/Plpp3/St6galnac4/Kit/Degs2/St8sia6/Sccpdh/Abca8b/Plpp1/St6galnac6/B3gnt5/St3gal4/Smpd1/Hacd1/Enpp2	23
GO:0001736	establishment of planar polarity	BP	0.194	3.36e-05	0.000357	3.45	0.000231	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Cplane1/Dchs1/Nphp1/Fzd2/Brsk1/Fat4/Dact1	12
GO:0051339	regulation of lyase activity	BP	0.194	3.36e-05	0.000357	3.45	0.000231	Cacna1c/Vipr2/Nos3/Npr3/Adcy3/Calca/Adcy4/Adcy7/Cap2/Palm/Gng7/Gabbr1	12
GO:1903034	regulation of response to wounding	BP	0.126	3.39e-05	0.00036	3.44	0.000233	Mdk/Cd109/Ddr2/Phldb2/Tfpi/Abat/Fermt2/Serpine2/Plpp3/Apoe/Pros1/Rtn4rl1/Neo1/Clec7a/Ptger3/Xylt1/St3gal4/Ptn/Cav1/Cldn1/F2r/Wfdc1	22
GO:0002062	chondrocyte differentiation	BP	0.148	3.56e-05	0.000375	3.43	0.000243	Col11a1/Ihh/Sfrp2/Mdk/Hoxd11/Pkdcc/Hoxa11/Mef2c/Osr2/Gli3/Pth1r/Wnt9a/Adamts7/Ltbp3/Osr1/Ccn2/Mboat2	17
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	BP	0.148	3.56e-05	0.000375	3.43	0.000243	Nlgn1/Ccdc88a/Nrp1/Abi2/Kit/Kctd17/Rp1/Eps8l1/Crocc/Ttbk2/Dzip1/Palm/Dpysl3/Cdc42ep5/Def8/Atmin/Zmynd8	17
GO:1904036	negative regulation of epithelial cell apoptotic process	BP	0.208	3.6e-05	0.000379	3.42	0.000245	Sema5a/Angpt1/Mdk/Kdr/Igf1/Tert/Icam1/Tek/Cdh5/Ndnf/Angptl4	11
GO:0033622	integrin activation	BP	0.286	3.66e-05	0.000383	3.42	0.000248	Fermt2/Col16a1/Fn1/Jam3/Cxcl12/Rasip1/Pcsk5/Plek	8
GO:0051894	positive regulation of focal adhesion assembly	BP	0.286	3.66e-05	0.000383	3.42	0.000248	Kdr/Nrp1/Fermt2/Col16a1/Tek/Thy1/Ppm1f/Enpp2	8
GO:0061437	renal system vasculature development	BP	0.286	3.66e-05	0.000383	3.42	0.000248	Angpt1/Nrp1/Tek/Tcf21/Ednra/Osr1/Pdgfrb/Bmp7	8
GO:0061440	kidney vasculature development	BP	0.286	3.66e-05	0.000383	3.42	0.000248	Angpt1/Nrp1/Tek/Tcf21/Ednra/Osr1/Pdgfrb/Bmp7	8
GO:0046629	gamma-delta T cell activation	BP	0.333	3.74e-05	0.000391	3.41	0.000253	Lef1/Itk/Jag2/Nckap1l/Stat5b/Gimap5/Gimap3	7
GO:0003073	regulation of systemic arterial blood pressure	BP	0.142	3.77e-05	0.000393	3.41	0.000255	Ar/Kdr/Ddah1/Adra1a/Nos3/Ptpro/P2rx2/Adamts16/Ednrb/Enpep/Edn3/Calca/Rps6ka2/Postn/Agtr1a/Apln/F2r/Eng	18
GO:0098657	import into cell	BP	0.112	3.87e-05	0.000402	3.4	0.000261	Slc1a3/Kcnj3/Cacna1c/Acsl6/Itga4/Slc6a2/Kcnd3/Slc12a8/Slc8a1/Slc9a7/Slc24a4/Slc7a2/Cacna1e/Slc8a3/Lrp2/Nalf1/Slc29a1/Agtr1a/Slc9a5/Slc12a4/Fyn/Acsl1/Atp1a2/Steap4/Psen1/Cacna1a/Lrrc8c	27
GO:0007164	establishment of tissue polarity	BP	0.19	3.97e-05	0.000412	3.39	0.000267	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Cplane1/Dchs1/Nphp1/Fzd2/Brsk1/Fat4/Dact1	12
GO:0060997	dendritic spine morphogenesis	BP	0.178	4.04e-05	0.000418	3.38	0.000271	Nlgn1/Lrrk2/Ppfia2/Dock10/Abi2/Kif1a/Nlgn3/Caprin2/Bhlhb9/Dlg4/Cux2/Ngef/Zfp365	13
GO:1902105	regulation of leukocyte differentiation	BP	0.102	4.11e-05	0.000424	3.37	0.000275	Ihh/Mdk/Lef1/Cd83/Hcls1/Cd44/Inpp4b/Pik3r6/Lrrc17/Gli3/Calca/Flt3/Loxl3/Zeb1/Prdm1/Cd1d1/Tnfrsf11b/Sox12/Zbtb46/Nckap1l/Kitl/Tal1/Tnfaip6/Rassf2/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il2rg/Il7r/Cd4/Myc	33
GO:0006820	anion transport	BP	0.0904	4.12e-05	0.000424	3.37	0.000275	Slc1a3/Car4/Grik1/Pla2g10/Slc13a5/Slc2a3/Tcaf1/Slc12a8/Abat/Drd4/Ano1/Slc7a2/Grin2b/Abcg2/Stc1/Slc36a4/Ano2/Ttyh2/Lrp2/Htr1b/Slc6a15/Glrb/Gabra4/Enpp1/Slc23a2/Bdkrb2/Sfxn5/Slc12a4/Slc38a1/Nfkbie/Slco4c1/Slc4a3/Ptger3/Clca2/Slc4a8/Psen1/Abcb1a/Abcc5/Gabbr1/Abcg3/Cacna1a/Lrrc8c/Cacnb4/Ank/Myc	45
GO:0034763	negative regulation of transmembrane transport	BP	0.136	4.29e-05	0.000442	3.35	0.000286	Hecw2/Drd4/Sh2b2/Enpp1/Dysf/Bin1/Osr1/Pkd2/Rrad/Ptger3/Gnb5/Gstm7/Atp1a2/Sri/Cav1/Pid1/Grb10/Myc/Twist1	19
GO:0070663	regulation of leukocyte proliferation	BP	0.108	4.48e-05	0.000461	3.34	0.000298	Ihh/Igf1/Cd44/Mef2c/Mapk8ip1/Tnfsf13b/Prdm1/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Cd38/Havcr2/Igf2/Nckap1l/Kitl/Xcl1/Stat5b/Pde5a/Csf2rb/H2-Aa/Dlg5/Zap70/Il12rb1/Spn/Cd4/Rasal3	29
GO:0045582	positive regulation of T cell differentiation	BP	0.151	4.61e-05	0.000472	3.33	0.000306	Ihh/Mdk/Lef1/Cd83/Pik3r6/Gli3/Cd1d1/Sox12/Nckap1l/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il2rg/Il7r	16
GO:0014910	regulation of smooth muscle cell migration	BP	0.158	4.63e-05	0.000472	3.33	0.000306	Cyp1b1/Mdk/Igf1/Ddr2/Drd4/Tert/Myo5a/Mef2c/Has2/Adamts1/Postn/Nox4/Pcsk5/Pdgfrb/Myc	15
GO:0019226	transmission of nerve impulse	BP	0.158	4.63e-05	0.000472	3.33	0.000306	Kcnd2/P2rx2/Scn1a/Jam3/Cacna1e/Scn2a/Grik2/Nfasc/Kcnma1/Kcnc4/Cacng7/Cacna1h/Scn3a/Cacna1a/Cacnb4	15
GO:0001952	regulation of cell-matrix adhesion	BP	0.14	4.66e-05	0.000475	3.32	0.000308	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Cdh13/Thy1/Postn/Ppm1f/Epha3/Limch1/Arhgap6/Vegfc/Pcsk5/Dlc1/Efemp2/Enpp2	18
GO:0050901	leukocyte tethering or rolling	BP	0.243	4.89e-05	0.000496	3.3	0.000322	Itga4/Chst2/Itgb7/Podxl2/Cxcl12/Sele/St3gal4/Spn/Jam2	9
GO:0050920	regulation of chemotaxis	BP	0.113	4.92e-05	0.000498	3.3	0.000323	Sema5a/Mdk/Kdr/Sema5b/Nrp1/Sema7a/Fn1/Prkd1/Jam3/Cxcr3/Cdh13/Cxcl12/Edn3/Ppm1f/Vegfc/Ednra/Sema3g/Dysf/Nckap1l/Xcl1/Tnfaip6/Mpp1/Adgra2/Sema6a/Pdgfrb/Ptn	26
GO:0098739	import across plasma membrane	BP	0.12	4.94e-05	0.000499	3.3	0.000324	Slc1a3/Kcnj3/Cacna1c/Acsl6/Kcnd3/Slc12a8/Slc8a1/Slc9a7/Slc24a4/Slc7a2/Cacna1e/Slc8a3/Lrp2/Nalf1/Agtr1a/Slc9a5/Slc12a4/Fyn/Acsl1/Atp1a2/Psen1/Cacna1a/Lrrc8c	23
GO:0030308	negative regulation of cell growth	BP	0.118	5e-05	0.000503	3.3	0.000326	Tro/Sfrp2/Map2/Sema5a/Wnt11/Sema5b/Nrp1/Sema7a/Serpine2/Cth/Minar1/Enpp1/Sema3g/Caprin2/Epha7/P3h1/Fhl1/Pi16/Rrad/Tspyl2/Sema6a/Ulk2/Slit3/Draxin	24
GO:0030500	regulation of bone mineralization	BP	0.165	5.09e-05	0.000512	3.29	0.000332	Ddr2/Pkdcc/Slc8a1/Mef2c/Osr2/Nell1/Mgp/Enpp1/Ltbp3/Osr1/Ptn/Bmp7/Ank/Twist1	14
GO:0097105	presynaptic membrane assembly	BP	0.5	5.24e-05	0.000525	3.28	0.00034	Ptprd/Nlgn1/Nlgn3/Lrp4/Nlgn2	5
GO:0002366	leukocyte activation involved in immune response	BP	0.101	5.24e-05	0.000525	3.28	0.00034	Mdk/Lef1/Itm2a/Foxf1/Icam1/Eif2ak4/Dock2/Lfng/Loxl3/Dock10/Coro1a/Kit/Itgal/Il27ra/Enpp1/Cracr2a/Havcr2/Irf8/Dysf/Nckap1l/Myo1f/Cd84/Fgr/Mfng/Psen1/Apbb1ip/Rab27a/Lat/Clnk/Pld2/Batf/Spn/Ly9	33
GO:1903170	negative regulation of calcium ion transmembrane transport	BP	0.217	5.32e-05	0.000532	3.27	0.000345	Drd4/Dysf/Bin1/Pkd2/Rrad/Ptger3/Gnb5/Gstm7/Atp1a2/Sri	10
GO:0042982	amyloid precursor protein metabolic process	BP	0.173	5.42e-05	0.00054	3.27	0.00035	Itm2a/Igf1/Aph1b/Rtn1/Soat1/Slc2a13/Apoe/Bin1/Nsg1/Abcg1/Adam19/Psen1/Tmcc2	13
GO:0097120	receptor localization to synapse	BP	0.173	5.42e-05	0.00054	3.27	0.00035	Gpc6/Nlgn1/Lrrc7/Cep112/Stx1b/Nptx1/Dlg2/Nptxr/Magi2/Nsg1/Cacng7/Dlg4/Kif5a	13
GO:0001954	positive regulation of cell-matrix adhesion	BP	0.185	5.48e-05	0.000545	3.26	0.000353	Kdr/Nrp1/Fermt2/Col16a1/Tek/Cdh13/Thy1/Ppm1f/Vegfc/Pcsk5/Efemp2/Enpp2	12
GO:0050670	regulation of lymphocyte proliferation	BP	0.11	5.54e-05	0.00055	3.26	0.000356	Ihh/Igf1/Cd44/Mef2c/Mapk8ip1/Tnfsf13b/Prdm1/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Cd38/Havcr2/Igf2/Nckap1l/Xcl1/Stat5b/Pde5a/H2-Aa/Dlg5/Zap70/Il12rb1/Spn/Cd4/Rasal3	27
GO:0048660	regulation of smooth muscle cell proliferation	BP	0.122	5.7e-05	0.000565	3.25	0.000366	Vipr2/Igf1/Ddr2/Nos3/Npr3/Drd4/Tert/Mmp2/Mef2c/Cdh13/Adamts1/Htr1b/Apoe/Rgs5/Stat5b/Irak4/Calcrl/Efemp2/Apln/Pdgfrb/Cav1/Myc	22
GO:0010001	glial cell differentiation	BP	0.108	5.73e-05	0.000566	3.25	0.000367	Gap43/Ptprz1/Mdk/Lef1/Nog/Igf1/Lamc3/Cdh2/Wasf3/Dab1/Id4/Serpine2/Gli3/Slc8a3/Plpp3/Nlgn3/Enpp1/Phgdh/Daam2/Bin1/Tal1/Nrros/Psen1/Ptn/Tppp/Itgb4/Enpp2/Zfp365	28
GO:0042102	positive regulation of T cell proliferation	BP	0.148	5.82e-05	0.000573	3.24	0.000372	Igf1/Tnfsf13b/Coro1a/Cd1d1/Itgal/Il27ra/Havcr2/Igf2/Nckap1l/Xcl1/Stat5b/Zap70/Il12rb1/Spn/Cd4/Rasal3	16
GO:0048041	focal adhesion assembly	BP	0.163	5.82e-05	0.000573	3.24	0.000372	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Thsd1/Tek/Thy1/Ppm1f/Epha3/Limch1/Arhgap6/Dlc1/Enpp2	14
GO:1901385	regulation of voltage-gated calcium channel activity	BP	0.237	6.14e-05	0.000604	3.22	0.000391	Drd4/Cacna2d1/Dysf/Stac2/Rrad/Gnb5/Sri/Cacna1a/Cacnb4	9
GO:0071709	membrane assembly	BP	0.196	6.15e-05	0.000604	3.22	0.000392	Ptprd/Nlgn1/Cdh2/Ubxn2b/Nlgn3/Magi2/Stx2/Cav1/Tlcd2/Lrp4/Nlgn2	11
GO:0010634	positive regulation of epithelial cell migration	BP	0.128	6.22e-05	0.000609	3.22	0.000395	Sema5a/Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Prkd1/Tek/Has2/Plpp3/Ppm1f/Jcad/Vegfc/Igf2/Hdac9/Akt3/Adgra2/Mapre2/Enpp2	20
GO:0002029	desensitization of G protein-coupled receptor signaling pathway	BP	0.267	6.33e-05	0.000615	3.21	0.000398	Calca/Htr1b/Aplnr/Arrb1/Arrb2/Ptger3/Apln/Pld2	8
GO:0022401	negative adaptation of signaling pathway	BP	0.267	6.33e-05	0.000615	3.21	0.000398	Calca/Htr1b/Aplnr/Arrb1/Arrb2/Ptger3/Apln/Pld2	8
GO:0045932	negative regulation of muscle contraction	BP	0.267	6.33e-05	0.000615	3.21	0.000398	Calca/Gucy1a1/Kcnma1/Bin1/Pde5a/Calcrl/Atp1a2/Sri	8
GO:0048596	embryonic camera-type eye morphogenesis	BP	0.267	6.33e-05	0.000615	3.21	0.000398	Stra6/Ihh/Tbx2/Zeb1/Hipk2/Hipk1/Bmp7/Twist1	8
GO:0048745	smooth muscle tissue development	BP	0.267	6.33e-05	0.000615	3.21	0.000398	Stra6/Ihh/Tshz3/Osr1/Efemp2/Pdgfrb/Itga8/Eng	8
GO:0060048	cardiac muscle contraction	BP	0.136	6.34e-05	0.000615	3.21	0.000398	Cacna1c/Sgcd/Kcnd3/Adra1a/Slc8a1/Scn4b/Scn1a/Cacna2d1/Stc1/Ank2/Bin1/Myl3/Pde5a/Cacna1h/Ccn2/Atp1a2/Sri/Cav1	18
GO:0070482	response to oxygen levels	BP	0.103	6.35e-05	0.000615	3.21	0.000398	Kcnk3/Kcnd2/Kdr/Ryr1/Ddah1/Abat/Slc8a1/Cbs/P2rx2/Pygm/Tert/Mmp2/Gucy1a2/Grin2b/Tek/Slc8a3/Gucy1b1/Gucy1a1/Scn2a/Vegfc/Cd38/Kcnma1/Ednra/Ndnf/Cav1/Cpeb1/Pld2/Hif3a/Myc/Twist1/Eng	31
GO:0001574	ganglioside biosynthetic process	BP	0.375	6.44e-05	0.000622	3.21	0.000403	St8sia2/St8sia4/St3gal2/St6galnac4/St8sia6/St6galnac6	6
GO:0010595	positive regulation of endothelial cell migration	BP	0.147	6.52e-05	0.000628	3.2	0.000407	Sema5a/Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Prkd1/Tek/Plpp3/Jcad/Vegfc/Igf2/Hdac9/Akt3/Adgra2	16
GO:0071901	negative regulation of protein serine/threonine kinase activity	BP	0.147	6.52e-05	0.000628	3.2	0.000407	Sfrp2/Slc8a1/Mapk8ip1/Slc8a3/Pkia/Cdkn1c/Apoe/Rasip1/Pkib/Heg1/Lats2/Smpd1/Cav1/Bmp7/Prkar1b/Lax1	16
GO:0035418	protein localization to synapse	BP	0.161	6.63e-05	0.000637	3.2	0.000412	Gpc6/Nlgn1/Stx1b/Nptx1/Slitrk3/Dlg2/Nlgn3/Nptxr/Magi2/Nsg1/Cacng7/Dlg4/Kif5a/Nlgn2	14
GO:0060411	cardiac septum morphogenesis	BP	0.161	6.63e-05	0.000637	3.2	0.000412	Wnt11/Nog/Tbx2/Nos3/Nrp1/Lrp2/Aplnr/Tbx3/Heyl/Fzd2/Bmp7/Hey2/Slit3/Eng	14
GO:0002263	cell activation involved in immune response	BP	0.0997	6.65e-05	0.000637	3.2	0.000413	Mdk/Lef1/Itm2a/Foxf1/Icam1/Eif2ak4/Dock2/Lfng/Loxl3/Dock10/Coro1a/Kit/Itgal/Il27ra/Enpp1/Cracr2a/Havcr2/Irf8/Dysf/Nckap1l/Myo1f/Cd84/Fgr/Mfng/Psen1/Apbb1ip/Rab27a/Lat/Clnk/Pld2/Batf/Spn/Ly9	33
GO:0022408	negative regulation of cell-cell adhesion	BP	0.115	6.82e-05	0.000652	3.19	0.000423	Ihh/Mdk/Lef1/Abat/Cd44/Serpine2/Cxcl12/Gli3/Podxl/Loxl3/Ppm1f/Ccm2l/H2-Ab1/Btla/Havcr2/Nckap1l/Pde5a/Ptger3/H2-Aa/Dlg5/Gimap5/Gimap3/Spn/Lax1	24
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.14	6.87e-05	0.000656	3.18	0.000425	Kdr/Zeb2/Rnf165/Npnt/Gpc3/Gdf11/Zfp423/Cdh5/Gdf7/Gdf10/Cdkn1c/Hipk2/Kcp/Neo1/Itga8/Bmp7/Eng	17
GO:0046467	membrane lipid biosynthetic process	BP	0.135	7.01e-05	0.000668	3.18	0.000433	St8sia2/St8sia4/Agk/Elovl4/Cerkl/Sptlc3/Cers4/St3gal2/St6galnac4/Degs2/St8sia6/Sccpdh/Abca8b/St6galnac6/B3gnt5/St3gal4/Smpd1/Hacd1	18
GO:0051250	negative regulation of lymphocyte activation	BP	0.124	7.13e-05	0.000678	3.17	0.00044	Ihh/Mdk/Cd44/Gli3/Flt3/Loxl3/Prdm1/H2-Ab1/Btla/Havcr2/Nckap1l/Pde5a/Fgr/H2-Aa/Dlg5/Gimap5/Gimap3/Clnk/Spn/Tbc1d10c/Lax1	21
GO:0046635	positive regulation of alpha-beta T cell activation	BP	0.169	7.19e-05	0.000683	3.17	0.000443	Ihh/Cd83/Gli3/Cd1d1/H2-Ab1/Nckap1l/Xcl1/Gimap5/Zap70/Gimap3/Il12rb1/Il2rg/Rasal3	13
GO:0006022	aminoglycan metabolic process	BP	0.145	7.29e-05	0.00069	3.16	0.000447	Angpt1/Cd44/Spock2/Ednrb/Has2/Egflam/Mamdc2/Chst1/Ednra/Ndnf/Tnfaip6/Bgn/Dse/Habp4/Xylt1/Pdgfrb	16
GO:0006493	protein O-linked glycosylation	BP	0.193	7.3e-05	0.00069	3.16	0.000447	Gxylt2/Tet1/Tmtc1/Galnt16/Eogt/St8sia6/Galntl6/Poglut2/Pomt2/Large1/Galnt18	11
GO:0032964	collagen biosynthetic process	BP	0.193	7.3e-05	0.00069	3.16	0.000447	Ihh/P3h3/Ddr2/Fn1/Emilin1/Rcn3/Arrb2/Ccn2/Pdgfrb/Cygb/F2r	11
GO:0032944	regulation of mononuclear cell proliferation	BP	0.108	7.32e-05	0.00069	3.16	0.000447	Ihh/Igf1/Cd44/Mef2c/Mapk8ip1/Tnfsf13b/Prdm1/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Btla/Cd38/Havcr2/Igf2/Nckap1l/Xcl1/Stat5b/Pde5a/H2-Aa/Dlg5/Zap70/Il12rb1/Spn/Cd4/Rasal3	27
GO:1990874	vascular associated smooth muscle cell proliferation	BP	0.179	7.47e-05	0.000704	3.15	0.000456	Igf1/Ddr2/Drd4/Tert/Mmp2/Mef2c/Adamts1/Htr1b/Enpp1/Rgs5/Efemp2/Apln	12
GO:0003281	ventricular septum development	BP	0.159	7.54e-05	0.000708	3.15	0.000459	Stra6/Wnt11/Nog/Nos3/Lrp2/Prdm1/Cplane1/Aplnr/Tbx3/Heyl/Heg1/Fzd2/Hey2/Slit3	14
GO:0006942	regulation of striated muscle contraction	BP	0.159	7.54e-05	0.000708	3.15	0.000459	Cacna1c/Adra1a/Slc8a1/Stc1/Ank2/Slc8a3/Bin1/Myl3/Pde5a/Cacna1h/Ccn2/Atp1a2/Sri/Cav1	14
GO:0045621	positive regulation of lymphocyte differentiation	BP	0.139	7.63e-05	0.000715	3.15	0.000463	Ihh/Mdk/Lef1/Cd83/Pik3r6/Gli3/Prdm1/Cd1d1/Sox12/Nckap1l/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il2rg/Il7r	17
GO:0043583	ear development	BP	0.108	8.39e-05	0.000784	3.11	0.000508	Col11a1/Stra6/Nog/Igf1/Tbx2/Lrig3/Osr2/Tshz1/Gli3/Zeb1/Jag2/Cecr2/Lin7a/Enpp1/Tsku/Tbx3/Kcnma1/Ednra/Dchs1/Osr1/Fzd2/Fat4/Kcnq4/Itga8/Ror1/Hey2/Myc	27
GO:0001508	action potential	BP	0.129	8.41e-05	0.000785	3.1	0.000509	Cacna1c/Kcnd2/Kcnd3/Adra1a/Scn4b/P2rx2/Scn1a/Cacna2d1/Grin2b/Ank2/Scn2a/Grik2/Kcnma1/Kcnc4/Bin1/Cacna1h/Scn3a/Cav1/Cacnb4	19
GO:0015849	organic acid transport	BP	0.0997	8.52e-05	0.000795	3.1	0.000515	Slc1a3/Acsl6/Grik1/Pla2g10/Slc13a5/Abat/Drd4/Slc7a2/Grin2b/Abcg2/Slc36a4/Rbp7/Lrp2/Htr1b/Slc6a15/Apoe/Slc23a2/Bdkrb2/Sfxn5/Slc38a1/Nfkbie/Abcd2/Acsl1/Slc7a7/Psen1/Abcb1a/Abcc5/Gabbr1/Cacna1a/Lrrc8c/Cacnb4/Myc	32
GO:0007517	muscle organ development	BP	0.0959	8.92e-05	0.00083	3.08	0.000538	Col11a1/Stra6/Angpt1/Lef1/Hoxd10/Ryr1/Nog/P2rx2/Hoxd9/Mef2c/Id3/Tcf21/Lrp2/Ccm2l/Ednra/Heyl/Igf2/Dysf/Myl3/Hdac9/Heg1/Selenon/Fhl1/Large1/Fzd2/Efemp2/Sgcb/Hlf/Zfp689/Cav1/Usp2/Hey2/Myc/Twist1/Eng	35
GO:0035701	hematopoietic stem cell migration	BP	0.455	9.23e-05	0.000854	3.07	0.000554	Jam3/Kit/Enpp1/Bcl11b/Jam2	5
GO:0045588	positive regulation of gamma-delta T cell differentiation	BP	0.455	9.23e-05	0.000854	3.07	0.000554	Lef1/Nckap1l/Stat5b/Gimap5/Gimap3	5
GO:0046645	positive regulation of gamma-delta T cell activation	BP	0.455	9.23e-05	0.000854	3.07	0.000554	Lef1/Nckap1l/Stat5b/Gimap5/Gimap3	5
GO:0061351	neural precursor cell proliferation	BP	0.116	9.33e-05	0.000862	3.06	0.000559	Gli1/Ptprz1/Acsl6/Hhip/Mdk/Lef1/Nog/Igf1/Zeb2/Cdh2/Lrrk2/Smarca1/Id4/Zfp423/Gli3/Lrp2/Kif1a/Eml1/Vegfc/Bbs1/Ptn/Nes/Numbl	23
GO:0008277	regulation of G protein-coupled receptor signaling pathway	BP	0.132	9.4e-05	0.000867	3.06	0.000562	Tub/Tmod2/Slc24a4/Plcb1/Calca/Htr1b/Aplnr/Arrb1/Arrb2/Pde5a/Ptger3/Atp2b4/Apln/Pld2/Kctd12b/Gpsm1/Kctd12/Plek	18
GO:0009311	oligosaccharide metabolic process	BP	0.225	9.44e-05	0.00087	3.06	0.000564	St6gal2/St8sia2/St8sia4/B3galnt1/St3gal2/St6galnac4/St8sia6/St6galnac6/St3gal4	9
GO:0001886	endothelial cell morphogenesis	BP	0.353	9.55e-05	0.000877	3.06	0.000568	Stc1/Pecam1/Col15a1/Heg1/Arhgef26/Col18a1	6
GO:1905564	positive regulation of vascular endothelial cell proliferation	BP	0.353	9.55e-05	0.000877	3.06	0.000568	Mdk/Itga4/Igf1/Igf2/Akt3/Apln	6
GO:0019915	lipid storage	BP	0.156	9.69e-05	0.000889	3.05	0.000576	Apob/Pla2g10/Acacb/Vstm2a/Mest/Soat1/Enpp1/Apoe/Dysf/Abcg1/Stat5b/Cav1/Nr1h3/Cds1	14
GO:0010842	retina layer formation	BP	0.292	9.82e-05	0.000898	3.05	0.000582	Sdk2/Arl6/Obsl1/Ptprm/Hipk2/Fat3/Hipk1	7
GO:0006941	striated muscle contraction	BP	0.121	9.99e-05	0.000913	3.04	0.000591	Cacna1c/Sgcd/Kcnd3/Adra1a/Slc8a1/Scn4b/Scn1a/Cacna2d1/Stc1/Ank2/Slc8a3/Bin1/Myl3/Stac2/Pde5a/Ryr3/Cacna1h/Ccn2/Atp1a2/Sri/Cav1	21
GO:0048863	stem cell differentiation	BP	0.108	1e-04	0.000914	3.04	0.000592	Sema5a/Zeb2/Sema5b/Nrp1/Sema7a/Cdh2/Fn1/Ednrb/Mef2c/Hoxd4/Edn3/Kit/Ednra/Sema3g/Prickle1/Kitl/Ltbp3/Tal1/Osr1/Pus7/Sema6a/Ptn/Batf/Bmp7/Hand2/Twist1	26
GO:0006940	regulation of smooth muscle contraction	BP	0.174	0.000101	0.000914	3.04	0.000592	Npnt/Adra1a/Abat/Calca/Gucy1a1/Kit/Kcnma1/Calcrl/Ptger3/Atp1a2/Cav1/F2r	12
GO:0045668	negative regulation of osteoblast differentiation	BP	0.174	0.000101	0.000914	3.04	0.000592	Nog/Areg/Id3/Gdf10/Vegfc/Rorb/Tnfaip6/Twist2/Ptch1/Hand2/Twist1/Zfp932	12
GO:0007612	learning	BP	0.118	0.000101	0.000917	3.04	0.000594	Stra6/Cacna1c/Jph4/Nog/Drd4/Chst10/B4galt2/Grin2b/Pde1b/Adcy3/Shank2/Cacna1e/Eif2ak4/Slc8a3/Kit/Nlgn3/Ddhd2/Atp1a2/Syngap1/Brsk1/Ptn/Bche	22
GO:0030278	regulation of ossification	BP	0.131	0.000103	0.000937	3.03	0.000607	Mdk/Ddr2/Pkdcc/Slc8a1/Mef2c/Osr2/Calca/Nell1/Mgp/Enpp1/Ltbp3/P3h1/Osr1/Ptn/Bmp7/Lrp4/Ank/Twist1	18
GO:0010875	positive regulation of cholesterol efflux	BP	0.25	0.000104	0.000943	3.03	0.000611	Pltp/Apoe/Ptch1/Abcg1/Abca8b/Cav1/Nr1h3/Abcg4	8
GO:0023058	adaptation of signaling pathway	BP	0.25	0.000104	0.000943	3.03	0.000611	Calca/Htr1b/Aplnr/Arrb1/Arrb2/Ptger3/Apln/Pld2	8
GO:0055001	muscle cell development	BP	0.11	0.000111	0.001	3	0.000651	Sgcd/Col14a1/Ryr1/Igf1/Adra1a/Slc8a1/P2rx2/Tmod2/Mef2c/Ank2/Tbx3/Ednra/Dysf/Bin1/Hdac9/Nfatc4/Flnc/Selenon/Pi16/Efemp2/Sgcb/Pdgfrb/Cacnb4/Hey2/Eng	25
GO:0048565	digestive tract development	BP	0.135	0.000115	0.00103	2.99	0.000668	Stra6/Ihh/Sfrp2/Clmp/Pkdcc/Tbx2/Ednrb/Foxf1/Tcf21/Gli3/Prdm1/Kit/Pcsk5/Dchs1/Fat4/Stx2/Dact1	17
GO:0035886	vascular associated smooth muscle cell differentiation	BP	0.22	0.000116	0.00104	2.98	0.000673	Kit/Cth/Aplnr/Ednra/Efemp2/Sgcb/Pdgfrb/Hey2/Eng	9
GO:0043368	positive T cell selection	BP	0.22	0.000116	0.00104	2.98	0.000673	Cd3g/Dock2/Loxl3/Cd1d1/Zap70/Batf/Spn/Ly9/Bcl11b	9
GO:0086065	cell communication involved in cardiac conduction	BP	0.22	0.000116	0.00104	2.98	0.000673	Cacna1c/Kcnd3/Slc8a1/Scn4b/Cacna2d1/Ank2/Gjc1/Sri/Cav1	9
GO:0030509	BMP signaling pathway	BP	0.119	0.000118	0.00105	2.98	0.000682	Sfrp2/Lef1/Kdr/Nog/Rnf165/Fst/Gpc3/Zfp423/Cdh5/Gdf7/Lrp2/Hipk2/Kcp/Tnfaip6/Smad9/Neo1/Fstl1/Cav1/Tmprss6/Bmp7/Eng	21
GO:0048738	cardiac muscle tissue development	BP	0.104	0.000118	0.00105	2.98	0.000682	Gli1/Col11a1/AW551984/Angpt1/Sgcd/Col14a1/Nog/Igf1/Tbx2/Adra1a/Slc8a1/Mef2c/Lrp2/Ccm2l/Nox4/Tbx3/Gjc1/Ednra/Myl3/Heg1/Arrb2/Pi16/Sgcb/Pdgfrb/Bmp7/Hey2/Hand2/Eng	28
GO:1902107	positive regulation of leukocyte differentiation	BP	0.116	0.000118	0.00105	2.98	0.000682	Ihh/Mdk/Lef1/Cd83/Hcls1/Pik3r6/Gli3/Calca/Prdm1/Cd1d1/Sox12/Zbtb46/Nckap1l/Kitl/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il2rg/Il7r/Cd4	22
GO:1903708	positive regulation of hemopoiesis	BP	0.116	0.000118	0.00105	2.98	0.000682	Ihh/Mdk/Lef1/Cd83/Hcls1/Pik3r6/Gli3/Calca/Prdm1/Cd1d1/Sox12/Zbtb46/Nckap1l/Kitl/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il2rg/Il7r/Cd4	22
GO:0035924	cellular response to vascular endothelial growth factor stimulus	BP	0.183	0.000119	0.00105	2.98	0.000683	Kdr/Nrp1/Ptp4a3/Prkd1/Jcad/Vegfc/Tcf4/Atp2b4/Adgra2/Sema6a/Pdgfrb	11
GO:0097479	synaptic vesicle localization	BP	0.183	0.000119	0.00105	2.98	0.000683	Syn2/Map2/Nlgn1/Cdh2/Lrrk2/Lin7a/Nlgn3/Magi2/Pcdh17/Kif5a/Nlgn2	11
GO:0001558	regulation of cell growth	BP	0.0889	0.000125	0.00111	2.96	0.000718	Tro/Sfrp2/Map2/Sema5a/Wnt11/Col14a1/Igf1/Ptch2/Sema5b/Epb41l3/Cpne5/Nrp1/Cd44/Sema7a/Fn1/Serpine2/Cxcl12/Klhl22/Kif26a/Cth/Minar1/Enpp1/Cd38/Apoe/Sema3g/Caprin2/Slc23a2/Epha7/Cacng7/P3h1/Fhl1/Pi16/Csf2rb/Rrad/Tspyl2/Sema6a/Ulk2/Igfbp4/Wfdc1/Slit3/Draxin	41
GO:0097529	myeloid leukocyte migration	BP	0.109	0.000128	0.00113	2.95	0.000734	Cxcl15/Mdk/Ptpro/Ednrb/Jam3/Cxcl12/Edn3/Itga1/Plcb1/Calca/Kit/Enpp1/Emilin1/Vegfc/Ednra/Pecam1/Cd200/Dysf/Nckap1l/Xcl1/Tnfaip6/Stat5b/Irak4/Ptger3/Mpp1	25
GO:0007202	activation of phospholipase C activity	BP	0.28	0.000131	0.00115	2.94	0.000746	Adra1a/Itk/Arhgap6/Sele/Adcyap1r1/Htr2a/Dlc1	7
GO:0101023	vascular endothelial cell proliferation	BP	0.28	0.000131	0.00115	2.94	0.000746	Mdk/Itga4/Igf1/Mef2c/Igf2/Akt3/Apln	7
GO:1905562	regulation of vascular endothelial cell proliferation	BP	0.28	0.000131	0.00115	2.94	0.000746	Mdk/Itga4/Igf1/Mef2c/Igf2/Akt3/Apln	7
GO:0060740	prostate gland epithelium morphogenesis	BP	0.242	0.000132	0.00116	2.94	0.00075	Ar/Cyp7b1/Nog/Igf1/Cd44/Mmp2/Id4/Bmp7	8
GO:0062149	detection of stimulus involved in sensory perception of pain	BP	0.242	0.000132	0.00116	2.94	0.00075	Scn1a/Ano1/Grin2b/Cxcl12/Calca/Htr2a/Arrb2/Fyn	8
GO:1905314	semi-lunar valve development	BP	0.242	0.000132	0.00116	2.94	0.00075	Stra6/Nos3/Emilin1/Tie1/Heyl/Hey2/Slit3/Twist1	8
GO:0046849	bone remodeling	BP	0.144	0.000134	0.00117	2.93	0.000756	Ihh/Mdk/Inpp4b/Calca/Htr1b/Pth1r/Enpp1/Tnfrsf11b/Cd38/Nox4/Syt7/Ltbp3/Rassf2/Def8/Ptn	15
GO:0055117	regulation of cardiac muscle contraction	BP	0.169	0.000134	0.00117	2.93	0.000756	Cacna1c/Adra1a/Slc8a1/Stc1/Ank2/Bin1/Pde5a/Cacna1h/Ccn2/Atp1a2/Sri/Cav1	12
GO:0008064	regulation of actin polymerization or depolymerization	BP	0.121	0.000136	0.00119	2.93	0.000769	Kank4/Sema5a/Evl/Hcls1/Tmod2/Pfn2/Icam1/Coro1a/Esam/Sh3bp1/Daam2/Pecam1/Scin/Bin1/Nckap1l/Arhgap28/Cdc42ep5/Plekhh2/Cyfip2/Plek	20
GO:0070665	positive regulation of leukocyte proliferation	BP	0.121	0.000136	0.00119	2.93	0.000769	Igf1/Mef2c/Tnfsf13b/Coro1a/Cd1d1/Itgal/Il27ra/Cd38/Havcr2/Igf2/Nckap1l/Kitl/Xcl1/Stat5b/Csf2rb/Zap70/Il12rb1/Spn/Cd4/Rasal3	20
GO:0042492	gamma-delta T cell differentiation	BP	0.333	0.000137	0.00119	2.92	0.000773	Lef1/Jag2/Nckap1l/Stat5b/Gimap5/Gimap3	6
GO:0099150	regulation of postsynaptic specialization assembly	BP	0.333	0.000137	0.00119	2.92	0.000773	Gap43/Ptprd/Lrrc4b/Nptx1/Nptxr/Arhgef9	6
GO:1902904	negative regulation of supramolecular fiber organization	BP	0.118	0.000138	0.0012	2.92	0.000775	Kank4/Map2/Evl/Phldb2/Tmod2/Pfn2/Cdh5/Coro1a/Rp1/Arhgap6/Tubb4a/Emilin1/Apoe/Pecam1/Tmeff2/Scin/Dysf/Dlc1/Arhgap28/Ttbk2/Plekhh2	21
GO:0098659	inorganic cation import across plasma membrane	BP	0.138	0.000139	0.0012	2.92	0.000775	Kcnj3/Cacna1c/Kcnd3/Slc12a8/Slc8a1/Slc9a7/Slc24a4/Cacna1e/Slc8a3/Nalf1/Agtr1a/Slc9a5/Slc12a4/Fyn/Atp1a2/Cacna1a	16
GO:0099587	inorganic ion import across plasma membrane	BP	0.138	0.000139	0.0012	2.92	0.000775	Kcnj3/Cacna1c/Kcnd3/Slc12a8/Slc8a1/Slc9a7/Slc24a4/Cacna1e/Slc8a3/Nalf1/Agtr1a/Slc9a5/Slc12a4/Fyn/Atp1a2/Cacna1a	16
GO:0042596	fear response	BP	0.18	0.000139	0.0012	2.92	0.000775	Ankfn1/Mdk/Drd4/Mef2c/Grin2b/Cacna1e/Grik2/Apoe/Gng7/Atp1a2/Prkar1b	11
GO:0045807	positive regulation of endocytosis	BP	0.133	0.000139	0.0012	2.92	0.000778	Angpt1/Nlgn1/Gpc3/Lrrk2/Lrp2/Apoe/Magi2/Sele/Hip1/Bin1/Nckap1l/Arrb1/Arrb2/Apln/Smpd1/Cav1/Pld2	17
GO:0006066	alcohol metabolic process	BP	0.0957	0.000146	0.00126	2.9	0.000816	Apob/Cyp1b1/Ttr/Cyp7b1/Hmgcs2/Ednrb/Soat1/Inpp4b/Sptlc3/Plcb1/Pth1r/Plpp3/Dkk3/Enpp1/Tsku/Apoe/Bpnt1/Kcnma1/Dysf/Degs2/Adcyap1r1/Abca5/Ipmk/Cyp46a1/Abcg1/Cacna1h/Sord/Plpp1/Smpd1/Lipe/Rdh1/Abcg4/Plek	33
GO:0072659	protein localization to plasma membrane	BP	0.0993	0.000149	0.00128	2.89	0.000827	Kcnb2/Ar/Pkdcc/Epb41l3/Ccdc88a/Arl6/Efr3b/Cdh2/Gga2/Abi3/Myo5a/Ank2/Rab34/Ttc7b/Epha3/Rilpl1/Nfasc/Nsg1/Stac2/Kcnip3/Ptch1/Dchs1/Tspan5/Palm/Atp2b4/Bbs1/Pid1/Nkd2/Golph3l/Rap2a	30
GO:0007369	gastrulation	BP	0.117	0.00015	0.00128	2.89	0.000831	Sfrp2/Lef1/Wnt11/Nog/Phldb2/Hoxa11/Fn1/Foxf1/Osr2/Plpp3/Tgif2/Aplnr/Col5a2/Snai1/Tal1/Osr1/Apln/Ets2/Dact1/Kif16b/Bmp7	21
GO:0042135	neurotransmitter catabolic process	BP	0.417	0.000152	0.0013	2.89	0.000842	Maob/Abat/Maoa/Naalad2/Bche	5
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.132	0.000153	0.00131	2.88	0.00085	Sfrp2/Cd109/Nog/Fst/Lrp2/Pbld2/Tsku/Emilin1/Magi2/Spred3/Hipk2/Tnfaip6/Nrros/Il17rd/Cav1/Tmprss6/Eng	17
GO:0042475	odontogenesis of dentin-containing tooth	BP	0.149	0.000156	0.00133	2.88	0.000863	Wnt6/Lef1/Apcdd1/Fst/Edaradd/Slc24a4/Gli3/Jag2/Tnfrsf11b/Edar/Bmp7/Lrp4/Hand2/Bcl11b	14
GO:0051899	membrane depolarization	BP	0.149	0.000156	0.00133	2.88	0.000863	Cacna1c/Grik1/Kdr/Scn4b/Bok/Lrrk2/Scn1a/Cacna2d1/Scn2a/Fhl1/Cacna1h/Scn3a/Cav1/Cacna1a	14
GO:0045580	regulation of T cell differentiation	BP	0.12	0.000161	0.00136	2.87	0.000884	Ihh/Mdk/Lef1/Cd83/Cd44/Pik3r6/Gli3/Loxl3/Zeb1/Prdm1/Cd1d1/Sox12/Nckap1l/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il2rg/Il7r	20
GO:0006584	catecholamine metabolic process	BP	0.177	0.000161	0.00136	2.87	0.000884	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Hdc/Agtr1a/Ednra/Sult1a1/Hand2	11
GO:0009712	catechol-containing compound metabolic process	BP	0.177	0.000161	0.00136	2.87	0.000884	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Hdc/Agtr1a/Ednra/Sult1a1/Hand2	11
GO:0010171	body morphogenesis	BP	0.177	0.000161	0.00136	2.87	0.000884	Stra6/Ihh/Lef1/Nog/Phldb2/Crispld1/Gpc3/Mmp2/Flvcr1/Twist2/Asph	11
GO:0031102	neuron projection regeneration	BP	0.177	0.000161	0.00136	2.87	0.000884	Gap43/Hgf/Mmp2/Thy1/Matn2/Enpp1/Rtn4rl1/Neo1/Xylt1/Ptn/Nrep	11
GO:0050906	detection of stimulus involved in sensory perception	BP	0.117	0.000162	0.00137	2.86	0.000885	Col11a1/Sema5a/Igf1/Sema5b/Scn1a/Slc24a4/Ano1/Grin2b/Serpine2/Cxcl12/Calca/Kit/Grik2/Ppef2/Htr2a/Plcb2/Arrb2/Fyn/Piezo2/Cacnb4/Myc	21
GO:0010863	positive regulation of phospholipase C activity	BP	0.235	0.000165	0.00139	2.86	0.000898	Adra1a/Itk/Arhgap6/Sele/Adcyap1r1/Htr2a/Dlc1/Pdgfrb	8
GO:0050654	chondroitin sulfate proteoglycan metabolic process	BP	0.235	0.000165	0.00139	2.86	0.000898	Igf1/Spock2/Egflam/Mamdc2/Ndnf/Bgn/Dse/Xylt1	8
GO:0060512	prostate gland morphogenesis	BP	0.235	0.000165	0.00139	2.86	0.000898	Ar/Cyp7b1/Nog/Igf1/Cd44/Mmp2/Id4/Bmp7	8
GO:1901020	negative regulation of calcium ion transmembrane transporter activity	BP	0.235	0.000165	0.00139	2.86	0.000898	Drd4/Dysf/Pkd2/Rrad/Gnb5/Gstm7/Atp1a2/Sri	8
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	BP	0.235	0.000165	0.00139	2.86	0.000898	Mdk/Itga4/Chst2/Ets1/Icam1/Cxcl12/Sele/St3gal4	8
GO:0021953	central nervous system neuron differentiation	BP	0.111	0.000169	0.00141	2.85	0.000915	Map2/Hoxd10/Dcc/Zeb2/Nrp1/Id4/Gli3/D16Ertd472e/Gdf7/Tsku/Cdh11/Dync2h1/Ndnf/Dclk2/Nin/Tal1/Lhx6/Ptch1/Ptger3/Psen1/Cacna1a/Bcl11b/Draxin	23
GO:0071902	positive regulation of protein serine/threonine kinase activity	BP	0.111	0.000169	0.00141	2.85	0.000915	Igf1/Zeb2/Fermt2/Drd4/Ccnd2/Lrrk2/Pik3r6/Edn3/Kit/Nox4/Kitl/Htr2a/Pkd1/Pkd2/Pde5a/Atp2b4/Acsl1/Psen1/Pdgfrb/Map4k2/C1qtnf9/Fgd2/Camk1	23
GO:0042474	middle ear morphogenesis	BP	0.269	0.000171	0.00143	2.85	0.000925	Nog/Osr2/Tshz1/Enpp1/Ednra/Osr1/Myc	7
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	BP	0.269	0.000171	0.00143	2.85	0.000925	Mdk/Itga4/Chst2/Ets1/Icam1/Sele/St3gal4	7
GO:0030832	regulation of actin filament length	BP	0.119	0.000174	0.00145	2.84	0.000938	Kank4/Sema5a/Evl/Hcls1/Tmod2/Pfn2/Icam1/Coro1a/Esam/Sh3bp1/Daam2/Pecam1/Scin/Bin1/Nckap1l/Arhgap28/Cdc42ep5/Plekhh2/Cyfip2/Plek	20
GO:0055067	monovalent inorganic cation homeostasis	BP	0.119	0.000174	0.00145	2.84	0.000938	Slc1a3/Car4/Slc12a8/Slc8a1/Lrrk2/Ednrb/Slc9a7/Dmxl2/Agtr1a/Lacc1/Kcnma1/Ednra/Slc9a5/Slc12a4/Slc4a3/Aqp11/Atp1a2/Slc4a8/Mllt6/Rab20	20
GO:0010717	regulation of epithelial to mesenchymal transition	BP	0.147	0.000175	0.00145	2.84	0.000942	Sfrp2/Mdk/Lef1/Nog/Mark1/Phldb2/Fermt2/Epha3/Spred3/Snai1/Il17rd/Bmp7/Twist1/Eng	14
GO:0031099	regeneration	BP	0.122	0.000186	0.00154	2.81	0.000998	Gli1/Gap43/Hgf/Mdk/Igf1/Mmp2/Cxcl12/Hopx/Thy1/Matn2/Enpp1/Dysf/Rtn4rl1/Neo1/Selenon/Large1/Xylt1/Ptn/Nrep	19
GO:0044091	membrane biogenesis	BP	0.175	0.000187	0.00154	2.81	0.001	Ptprd/Nlgn1/Cdh2/Ubxn2b/Nlgn3/Magi2/Stx2/Cav1/Tlcd2/Lrp4/Nlgn2	11
GO:0072678	T cell migration	BP	0.175	0.000187	0.00154	2.81	0.001	Itga4/Itgb7/Icam1/Cxcr3/Cxcl12/Msn/Itgal/Il27ra/Cd200/Xcl1/Spn	11
GO:0006525	arginine metabolic process	BP	0.316	0.000193	0.00158	2.8	0.00103	Ddah1/Nos3/Fah/Atp2b4/Slc7a7/Asl	6
GO:0014051	gamma-aminobutyric acid secretion	BP	0.316	0.000193	0.00158	2.8	0.00103	Grik1/Abat/Htr1b/Gabbr1/Cacna1a/Cacnb4	6
GO:0035641	locomotory exploration behavior	BP	0.316	0.000193	0.00158	2.8	0.00103	Lrrk2/Apoe/Dlg4/Atp1a2/Lsamp/Nlgn2	6
GO:0032271	regulation of protein polymerization	BP	0.11	0.000195	0.0016	2.8	0.00104	Kank4/Map2/Evl/Hcls1/Tmod2/Pfn2/Icam1/Cdh5/Coro1a/Esam/Tubb4a/Daam2/Pecam1/Scin/Bin1/Nckap1l/Nin/Slain1/Arhgap28/Cdc42ep5/Cav1/Cyfip2/Tppp	23
GO:0002687	positive regulation of leukocyte migration	BP	0.121	0.000202	0.00166	2.78	0.00107	Mdk/Itga4/Icam1/Jam3/Cxcl12/Edn3/Thy1/Vegfc/Sele/Ednra/Pecam1/Dysf/Nckap1l/Kitl/Xcl1/Ptger3/Ptn/Spn/Jam2	19
GO:0030856	regulation of epithelial cell differentiation	BP	0.121	0.000202	0.00166	2.78	0.00107	Cd109/Macroh2a2/Zeb2/Ptch2/Plcb1/Cdh5/Zeb1/Cdkn1c/Tbx3/Spred3/Ptch1/Stat5b/Osr1/Cldn5/Fat4/Cav1/Akap11/Hey2/S1pr3	19
GO:1904064	positive regulation of cation transmembrane transport	BP	0.118	0.000205	0.00167	2.78	0.00108	Cacna1c/Drd4/Cacna2d1/Cxcr3/Ank2/Edn3/Plcb1/Thy1/Aplnr/Nlgn3/Cracr2a/Agtr1a/Ednra/Stac2/Asph/Pkd2/Gstm7/Sri/Cacnb4/F2r	20
GO:0010837	regulation of keratinocyte proliferation	BP	0.229	0.000205	0.00168	2.78	0.00109	Mdk/Cd109/Prkd1/Has2/Stxbp4/Klf9/Twist2/Bcl11b	8
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	BP	0.172	0.000216	0.00176	2.75	0.00114	Igf1/Ddr2/Drd4/Tert/Mmp2/Mef2c/Adamts1/Htr1b/Rgs5/Efemp2/Apln	11
GO:0032330	regulation of chondrocyte differentiation	BP	0.185	0.00022	0.00179	2.75	0.00116	Mdk/Hoxd11/Pkdcc/Hoxa11/Gli3/Wnt9a/Adamts7/Ltbp3/Ccn2/Mboat2	10
GO:0030204	chondroitin sulfate metabolic process	BP	0.259	0.000222	0.0018	2.75	0.00116	Spock2/Egflam/Mamdc2/Ndnf/Bgn/Dse/Xylt1	7
GO:0072012	glomerulus vasculature development	BP	0.259	0.000222	0.0018	2.75	0.00116	Angpt1/Tek/Tcf21/Ednra/Osr1/Pdgfrb/Bmp7	7
GO:0052547	regulation of peptidase activity	BP	0.088	0.000222	0.0018	2.75	0.00116	Hgf/Sfrp2/Cd109/Spink1/Igf1/Aph1b/Tfpi/Cd44/Bok/Gpc3/Wdr35/Grin2b/Mical1/Serpine2/Ift57/Wfdc3/Serpini1/Wnt9a/Ppm1f/Hip1/Bin1/Arrb1/Rcn3/Epha7/Dlc1/Arrb2/Asph/Fyn/Nlrp1b/Pi16/Ccn2/Simc1/Pi15/Mgmt/Cav1/Cyfip2/F2r/Wfdc1/Myc	39
GO:0061041	regulation of wound healing	BP	0.128	0.000223	0.0018	2.75	0.00116	Cd109/Ddr2/Phldb2/Tfpi/Abat/Fermt2/Serpine2/Plpp3/Apoe/Pros1/Clec7a/Ptger3/St3gal4/Cav1/Cldn1/F2r/Wfdc1	17
GO:2000027	regulation of animal organ morphogenesis	BP	0.128	0.000223	0.0018	2.75	0.00116	Hgf/Sfrp2/Ar/Apcdd1/Wnt11/Hoxd11/Nog/Nkd1/Hoxa11/Gpc3/Znrf3/Tnfrsf11b/Agtr1a/Ednra/Fzd2/Dact1/Bmp7	17
GO:0045669	positive regulation of osteoblast differentiation	BP	0.16	0.000229	0.00184	2.74	0.00119	Sfrp2/Igf1/Ddr2/Npnt/Fermt2/Mef2c/Prkd1/Gli3/Nell1/Gdf10/Lrp3/Bmp7	12
GO:0030323	respiratory tube development	BP	0.105	0.000233	0.00187	2.73	0.00121	Gli1/Stra6/Hhip/Kdr/Nog/Igf1/Pkdcc/Tbx2/Nos3/Gpc3/Foxf1/Hopx/Tcf21/Gli3/Loxl3/Tshz3/Mgp/Ltbp3/Pcsk5/Rcn3/Heg1/Selenon/Ccn2/Dlg5/Pdgfrb	25
GO:0060541	respiratory system development	BP	0.101	0.000234	0.00187	2.73	0.00121	Gli1/Stra6/Hhip/Lef1/Kdr/Nog/Igf1/Pkdcc/Tbx2/Nos3/Edaradd/Gpc3/Ano1/Foxf1/Hopx/Tcf21/Gli3/Loxl3/Tshz3/Mgp/Ltbp3/Rcn3/Heg1/Selenon/Ccn2/Dlg5/Pdgfrb	27
GO:0002087	regulation of respiratory gaseous exchange by nervous system process	BP	0.385	0.000237	0.00189	2.72	0.00123	Nlgn1/Tshz3/Nlgn3/Atp1a2/Nlgn2	5
GO:0097084	vascular associated smooth muscle cell development	BP	0.385	0.000237	0.00189	2.72	0.00123	Ednra/Efemp2/Sgcb/Hey2/Eng	5
GO:0032091	negative regulation of protein binding	BP	0.143	0.000245	0.00195	2.71	0.00126	Map2/Itga4/Nog/Lrrk2/Ccm2l/Dysf/Nfatc4/Arrb2/Ttbk2/Nes/Cav1/Dact1/Camk1/Myc	14
GO:1904063	negative regulation of cation transmembrane transport	BP	0.143	0.000245	0.00195	2.71	0.00126	Hecw2/Drd4/Dysf/Bin1/Osr1/Pkd2/Rrad/Ptger3/Gnb5/Gstm7/Atp1a2/Sri/Cav1/Twist1	14
GO:0050918	positive chemotaxis	BP	0.2	0.000247	0.00196	2.71	0.00127	Sema5a/Angpt1/Kdr/Nrp1/Cdh13/Cxcl12/Lrp2/Coro1a/Vegfc	9
GO:0071825	protein-lipid complex subunit organization	BP	0.2	0.000247	0.00196	2.71	0.00127	Apob/Pla2g10/Soat1/Pltp/Apoe/Bin1/Abca5/Abcg1/Pcdhga3	9
GO:0003229	ventricular cardiac muscle tissue development	BP	0.169	0.000249	0.00197	2.7	0.00128	Col11a1/Col14a1/Nog/Lrp2/Ccm2l/Tbx3/Ednra/Myl3/Heg1/Hey2/Eng	11
GO:0048048	embryonic eye morphogenesis	BP	0.222	0.000253	0.002	2.7	0.0013	Stra6/Ihh/Tbx2/Zeb1/Hipk2/Hipk1/Bmp7/Twist1	8
GO:0050671	positive regulation of lymphocyte proliferation	BP	0.122	0.000254	0.00201	2.7	0.0013	Igf1/Mef2c/Tnfsf13b/Coro1a/Cd1d1/Itgal/Il27ra/Cd38/Havcr2/Igf2/Nckap1l/Xcl1/Stat5b/Zap70/Il12rb1/Spn/Cd4/Rasal3	18
GO:0001662	behavioral fear response	BP	0.182	0.000258	0.00203	2.69	0.00132	Ankfn1/Mdk/Drd4/Mef2c/Grin2b/Cacna1e/Grik2/Apoe/Gng7/Atp1a2	10
GO:0062012	regulation of small molecule metabolic process	BP	0.0916	0.000263	0.00207	2.68	0.00134	Apob/Igf1/Nos3/Acacb/Pth1r/Kit/Dkk3/Enpp1/Apoe/Lacc1/Kcnma1/Igf2/Snai1/Adcyap1r1/Htr2a/Zbtb20/Abcg1/Atp2b4/Fam3c/Abcd2/Slc7a7/Psen1/Cav1/Nr1h3/Pid1/Cacna1a/Igfbp4/Grb10/Rdh1/Abcg4/Myc/Twist1/Plek/Irs1	34
GO:0043116	negative regulation of vascular permeability	BP	0.3	0.000264	0.00208	2.68	0.00135	Angpt1/Ddah1/Fermt2/Akap12/Apoe/Cldn5	6
GO:0043405	regulation of MAP kinase activity	BP	0.11	0.000267	0.0021	2.68	0.00136	Sfrp2/Zeb2/Cbs/Drd4/Lrrk2/Mapk8ip1/Pik3r6/Edn3/Kit/Apoe/Nox4/Kitl/Htr2a/Pde5a/Smpd1/Psen1/Pdgfrb/Map4k2/Cav1/Fgd2/Bmp7/Lax1	22
GO:1905475	regulation of protein localization to membrane	BP	0.11	0.000267	0.0021	2.68	0.00136	Gpc6/Ar/Pkdcc/Tcaf1/Cdh2/Gpc3/Abi3/Myo5a/Epha3/Magi2/Tnfaip6/Stac2/Fyn/Dlg4/Atp2b4/Ptn/Pid1/Gpc2/Nkd2/Zmynd8/Lrp4/Nlgn2	22
GO:0003014	renal system process	BP	0.13	0.000276	0.00216	2.67	0.0014	Cacna1c/Adra1a/Ptpro/Npr3/Ednrb/Abcg2/Stc1/Maged2/Agtr1a/Kcnma1/Ednra/Ptger3/Akap11/Abcg3/F2r/Mllt6	16
GO:0045061	thymic T cell selection	BP	0.25	0.000284	0.00222	2.65	0.00144	Cd3g/Gli3/Dock2/Jag2/Cd1d1/Zap70/Spn	7
GO:0060323	head morphogenesis	BP	0.196	0.000294	0.00229	2.64	0.00148	Stra6/Ihh/Lef1/Nog/Crispld1/Mmp2/Flvcr1/Twist2/Asph	9
GO:1903115	regulation of actin filament-based movement	BP	0.196	0.000294	0.00229	2.64	0.00148	Cacna1c/Stc1/Ank2/Bin1/Cacna1h/Ptger3/Atp1a2/Sri/Cav1	9
GO:0006029	proteoglycan metabolic process	BP	0.156	0.000294	0.00229	2.64	0.00149	Col11a1/Ihh/Igf1/Spock2/Chst10/Egflam/Mamdc2/Ndnf/Adamts7/Bgn/Dse/Xylt1	12
GO:0007588	excretion	BP	0.179	0.000301	0.00233	2.63	0.00151	Cacna1c/Mdk/Adra1a/Ednrb/Abcg2/Stc1/Kcnma1/Ptger3/Abcg3/Mllt6	10
GO:0061001	regulation of dendritic spine morphogenesis	BP	0.179	0.000301	0.00233	2.63	0.00151	Nlgn1/Lrrk2/Ppfia2/Abi2/Kif1a/Nlgn3/Caprin2/Bhlhb9/Cux2/Ngef	10
GO:0032946	positive regulation of mononuclear cell proliferation	BP	0.121	0.000301	0.00233	2.63	0.00151	Igf1/Mef2c/Tnfsf13b/Coro1a/Cd1d1/Itgal/Il27ra/Cd38/Havcr2/Igf2/Nckap1l/Xcl1/Stat5b/Zap70/Il12rb1/Spn/Cd4/Rasal3	18
GO:0046777	protein autophosphorylation	BP	0.103	0.000301	0.00233	2.63	0.00151	Epha8/Kdr/Ddr2/Lrrk2/Prkd1/Itk/Tek/Eif2ak4/Stk33/Flt3/Thy1/Kit/Enpp1/Vegfc/Epha7/Rassf2/Fyn/Fgr/Zap70/Ulk2/Pdgfrb/Cav1/Mknk2/Rap2a/Eng	25
GO:0042552	myelination	BP	0.114	0.000302	0.00233	2.63	0.00151	Ptprz1/Hgf/Igf1/Epb41l3/Mpdz/Cdh2/Wasf3/Myo5a/Id4/Jam3/Slc8a3/Enpp1/Nfasc/Fyn/Cldn5/Abcd2/Ptn/Tppp/Itgb4/Jam2	20
GO:0032092	positive regulation of protein binding	BP	0.14	0.000303	0.00234	2.63	0.00152	Tert/Lrrk2/Plxnd1/Lfng/Apoe/Caprin2/Pkd1/Hipk2/Arrb1/Cldn5/Mfng/Psen1/Cav1/Dact1	14
GO:0048846	axon extension involved in axon guidance	BP	0.216	0.000309	0.00237	2.62	0.00154	Sema5a/Sema5b/Nrp1/Sema7a/Cxcl12/Sema3g/Sema6a/Slit3	8
GO:0061384	heart trabecula morphogenesis	BP	0.216	0.000309	0.00237	2.62	0.00154	Nog/Tek/Adamts1/Ccm2l/Heg1/Bmp7/Hey2/Eng	8
GO:0090022	regulation of neutrophil chemotaxis	BP	0.216	0.000309	0.00237	2.62	0.00154	Mdk/Jam3/Ednra/Dysf/Nckap1l/Xcl1/Tnfaip6/Mpp1	8
GO:1902284	neuron projection extension involved in neuron projection guidance	BP	0.216	0.000309	0.00237	2.62	0.00154	Sema5a/Sema5b/Nrp1/Sema7a/Cxcl12/Sema3g/Sema6a/Slit3	8
GO:0030258	lipid modification	BP	0.106	0.000315	0.00241	2.62	0.00156	Acacb/Soat1/Agk/Inpp4b/St3gal2/Plpp3/Bdh2/Dgkb/Agtr1a/Apoe/Ggta1/Echs1/Abcg1/Plpp1/Abcd2/St3gal4/Cygb/C1qtnf9/Twist1/Mboat2/Plppr2/Echdc2/Irs1	23
GO:0050773	regulation of dendrite development	BP	0.124	0.000318	0.00243	2.61	0.00158	Ptprz1/Hecw2/Ptprd/Mark1/Tbc1d24/Obsl1/Trpc6/Caprin2/Nfatc4/Sarm1/Bhlhb9/Cux2/Fat3/Ptn/Bmp7/Numbl/Rap2a	17
GO:0021537	telencephalon development	BP	0.101	0.000319	0.00243	2.61	0.00158	Mdk/Lef1/Zeb2/Sema7a/Cdh2/Lrrk2/Dab1/Id4/Fut10/Cxcl12/Dnah5/Gli3/Plcb1/Tsku/Dclk2/Nin/Lhx6/Rtn4rl1/Nr2f1/Atp1a2/Fat4/Bbs1/Psen1/Bcl11b/Draxin/Numbl	26
GO:0045137	development of primary sexual characteristics	BP	0.102	0.00032	0.00244	2.61	0.00158	Sfrp2/Ar/Angpt1/Kdr/Nos3/Fst/Hoxa11/Hoxa10/Mmp2/Icam1/Adamts1/Tcf21/Lrp2/Lfng/Kit/Rhobtb3/Kitl/Arrb1/Tnfaip6/Hoxa9/Arrb2/Stat5b/Osr1/Abcb1a/Lhfpl2	25
GO:0002040	sprouting angiogenesis	BP	0.128	0.000332	0.00253	2.6	0.00164	Sema5a/Angpt1/Lef1/Kdr/Nrp1/Tek/Cdh13/Ppp1r16b/Aplnr/Jcad/Vegfc/Agtr1a/Hdac9/Akt3/Adgra2/Sema6a	16
GO:0045586	regulation of gamma-delta T cell differentiation	BP	0.357	0.000354	0.00268	2.57	0.00173	Lef1/Nckap1l/Stat5b/Gimap5/Gimap3	5
GO:0046643	regulation of gamma-delta T cell activation	BP	0.357	0.000354	0.00268	2.57	0.00173	Lef1/Nckap1l/Stat5b/Gimap5/Gimap3	5
GO:0051152	positive regulation of smooth muscle cell differentiation	BP	0.357	0.000354	0.00268	2.57	0.00173	Tshz3/Kit/Cth/Efemp2/Eng	5
GO:0051967	negative regulation of synaptic transmission, glutamatergic	BP	0.357	0.000354	0.00268	2.57	0.00173	Grik1/Myo5a/Htr1b/Grik2/Htr2a	5
GO:1905809	negative regulation of synapse organization	BP	0.357	0.000354	0.00268	2.57	0.00173	Apoe/Arhgef15/Nfatc4/Epha7/Ptn	5
GO:0050921	positive regulation of chemotaxis	BP	0.119	0.000355	0.00268	2.57	0.00173	Sema5a/Mdk/Kdr/Nrp1/Fn1/Prkd1/Cxcr3/Cdh13/Cxcl12/Edn3/Ppm1f/Vegfc/Ednra/Dysf/Nckap1l/Xcl1/Pdgfrb/Ptn	18
GO:0007338	single fertilization	BP	0.116	0.000355	0.00268	2.57	0.00174	Ar/Pla2g10/Hoxd10/Hoxd11/Spink1/Hoxa11/Hoxd9/Hoxa10/Adcy3/Plcb1/Trpc6/Glrb/Cecr2/Hoxa9/Cacna1h/Ccdc136/Stx2/Pkdrej/Lhfpl2	19
GO:1900027	regulation of ruffle assembly	BP	0.241	0.000359	0.0027	2.57	0.00175	Evl/Nlgn1/Pfn2/Icam1/Eps8l1/Def8/Cav1	7
GO:0002228	natural killer cell mediated immunity	BP	0.144	0.000361	0.00272	2.57	0.00176	Pik3r6/Coro1a/Cd226/Havcr2/Igf2/Arrb2/Stat5b/Gimap5/Gzmb/Gimap3/Rab27a/Clnk/Cd96	13
GO:0032414	positive regulation of ion transmembrane transporter activity	BP	0.127	0.000363	0.00273	2.56	0.00177	Tcaf1/Drd4/Cacna2d1/Myo5a/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Ednra/Stac2/Asph/Pkd2/Gstm7/Abcb1a/Cacnb4	16
GO:0030099	myeloid cell differentiation	BP	0.0866	0.00037	0.00278	2.56	0.0018	Lef1/Pla2g10/Cd109/P4htm/Hcls1/Ets1/Gpc3/Mef2c/Inpp4b/Flvcr1/Lrrc17/Plcb1/Calca/Fli1/Kit/Heph/Enpp1/Cdkn1c/Tnfrsf11b/Gpr171/Irf8/Zbtb46/Scin/Nckap1l/Kitl/Tal1/Tnfaip6/Hoxa9/Twist2/Rassf2/Nrros/Stat5b/Gimap5/Gimap3/Psen1/Batf/Cd4/Myc	38
GO:0061337	cardiac conduction	BP	0.162	0.000374	0.0028	2.55	0.00182	Cacna1c/Kcnd3/Slc8a1/Scn4b/Cacna2d1/Ank2/Gjc1/Bin1/Slc4a3/Sri/Cav1	11
GO:0086004	regulation of cardiac muscle cell contraction	BP	0.211	0.000376	0.0028	2.55	0.00182	Cacna1c/Stc1/Ank2/Bin1/Cacna1h/Atp1a2/Sri/Cav1	8
GO:1900274	regulation of phospholipase C activity	BP	0.211	0.000376	0.0028	2.55	0.00182	Adra1a/Itk/Arhgap6/Sele/Adcyap1r1/Htr2a/Dlc1/Pdgfrb	8
GO:0008366	axon ensheathment	BP	0.112	0.000377	0.00281	2.55	0.00182	Ptprz1/Hgf/Igf1/Epb41l3/Mpdz/Cdh2/Wasf3/Myo5a/Id4/Jam3/Slc8a3/Enpp1/Nfasc/Fyn/Cldn5/Abcd2/Ptn/Tppp/Itgb4/Jam2	20
GO:0051258	protein polymerization	BP	0.0978	0.000396	0.00294	2.53	0.00191	Kank4/Map2/Evl/Hcls1/Tmod2/Pfn2/Icam1/Cdh5/Catip/Coro1a/Esam/Rp1/Tubb4a/Daam2/Pecam1/Scin/Bin1/Nckap1l/Nin/Slain1/Arhgap28/Cdc42ep5/Cav1/Cyfip2/Tppp/Map7d3/Pstpip1	27
GO:0051101	regulation of DNA binding	BP	0.126	0.000398	0.00295	2.53	0.00191	Lef1/Igf1/Zfp462/Runx1t1/Zc4h2/Hipk2/Twist2/Habp4/Zfp90/Psen1/Sri/Hipk1/Hey2/Hand2/Myc/Twist1	16
GO:0042311	vasodilation	BP	0.172	0.000404	0.00299	2.52	0.00194	Kdr/Npr3/Ednrb/Itga1/Ptprm/Calca/Gucy1a1/Apoe/Kcnma1/Bdkrb2	10
GO:0032965	regulation of collagen biosynthetic process	BP	0.188	0.00041	0.00303	2.52	0.00196	Ihh/Ddr2/Fn1/Emilin1/Arrb2/Ccn2/Pdgfrb/Cygb/F2r	9
GO:0035137	hindlimb morphogenesis	BP	0.188	0.00041	0.00303	2.52	0.00196	Hoxd10/Aff3/Gpc3/Hoxd9/Osr2/Tbx3/Ptch1/Osr1/Twist1	9
GO:0042073	intraciliary transport	BP	0.188	0.00041	0.00303	2.52	0.00196	Tub/Wdr35/Ift57/Dync2h1/Ttc26/Arl3/Dync2li1/Bbs1/Ift81	9
GO:0046513	ceramide biosynthetic process	BP	0.159	0.000426	0.00314	2.5	0.00203	St8sia2/St8sia4/Agk/Sptlc3/Cers4/St3gal2/St6galnac4/Degs2/St8sia6/St6galnac6/Smpd1	11
GO:0051251	positive regulation of lymphocyte activation	BP	0.0858	0.000441	0.00325	2.49	0.0021	Ihh/Efnb3/Mdk/Lef1/Cd83/Igf1/Mef2c/Pik3r6/Gli3/Thy1/Tnfsf13b/Prdm1/Coro1a/Cd1d1/Itgal/H2-Ab1/Il27ra/Cd38/Sox12/Havcr2/H2-Ob/Igf2/Nckap1l/Xcl1/H2-Eb1/Stat5b/Clec7a/H2-Aa/Gimap5/Zap70/Gimap3/Il12rb1/Cav1/Il2rg/Spn/Il7r/Cd4/Rasal3	38
GO:0045724	positive regulation of cilium assembly	BP	0.233	0.000448	0.0033	2.48	0.00214	Ccdc88a/Kctd17/Rp1/Crocc/Ttbk2/Dzip1/Atmin	7
GO:1903035	negative regulation of response to wounding	BP	0.141	0.000449	0.0033	2.48	0.00214	Mdk/Cd109/Phldb2/Tfpi/Abat/Serpine2/Apoe/Pros1/Rtn4rl1/Neo1/Ptger3/Xylt1/Wfdc1	13
GO:1904645	response to amyloid-beta	BP	0.205	0.000453	0.00332	2.48	0.00215	Itga4/Igf1/Cacna2d1/Mmp2/Icam1/Fyn/Psen1/Cacna1a	8
GO:0030324	lung development	BP	0.102	0.000466	0.0034	2.47	0.0022	Gli1/Stra6/Hhip/Kdr/Nog/Igf1/Pkdcc/Tbx2/Nos3/Gpc3/Foxf1/Hopx/Tcf21/Gli3/Loxl3/Tshz3/Mgp/Ltbp3/Rcn3/Heg1/Selenon/Ccn2/Dlg5/Pdgfrb	24
GO:0002285	lymphocyte activation involved in immune response	BP	0.104	0.000466	0.0034	2.47	0.0022	Mdk/Lef1/Itm2a/Icam1/Eif2ak4/Lfng/Loxl3/Dock10/Coro1a/Itgal/Il27ra/Enpp1/Cracr2a/Havcr2/Irf8/Nckap1l/Mfng/Psen1/Apbb1ip/Rab27a/Batf/Spn/Ly9	23
GO:1903828	negative regulation of protein localization	BP	0.104	0.000466	0.0034	2.47	0.0022	Angpt1/Pkdcc/Drd4/Lrrk2/Abi3/Pkia/Ppm1f/Ubxn2b/Apoe/Cd200/Dclk2/Nin/Neo1/Frmd4a/Ttbk2/Rab23/Ptger3/Lats2/Nr1h3/Pid1/F2r/Ankrd13a/Irs1	23
GO:0003180	aortic valve morphogenesis	BP	0.273	0.000468	0.0034	2.47	0.0022	Nos3/Emilin1/Tie1/Hey2/Slit3/Twist1	6
GO:0060080	inhibitory postsynaptic potential	BP	0.273	0.000468	0.0034	2.47	0.0022	Grik1/Abat/Drd4/Grik2/Nlgn3/Nlgn2	6
GO:0072111	cell proliferation involved in kidney development	BP	0.273	0.000468	0.0034	2.47	0.0022	Gpc3/Ptch1/Osr1/Pdgfrb/Bmp7/Myc	6
GO:0072578	neurotransmitter-gated ion channel clustering	BP	0.273	0.000468	0.0034	2.47	0.0022	Nlgn1/Slitrk3/Glrb/Apoe/Dlg4/Nlgn2	6
GO:0008202	steroid metabolic process	BP	0.0917	0.000473	0.00343	2.46	0.00222	Apob/Cyp3a59/Cyp1b1/Cyp3a25/Cyp7b1/Nr5a2/Igf1/Hmgcs2/Ednrb/Soat1/Chst10/Kit/Dkk3/Enpp1/Tsku/Agtr1a/Apoe/Kcnma1/Igf2/Snai1/Ebpl/Abca5/Cyp46a1/Abcg1/Stat5b/Cacna1h/Smpd1/Lipe/Sult1a1/Rdh1/Abcg4	31
GO:0015711	organic anion transport	BP	0.0907	0.000474	0.00343	2.46	0.00222	Slc1a3/Car4/Grik1/Pla2g10/Slc13a5/Slc2a3/Abat/Drd4/Slc7a2/Grin2b/Abcg2/Slc36a4/Lrp2/Htr1b/Slc6a15/Slc23a2/Bdkrb2/Sfxn5/Slc38a1/Nfkbie/Slco4c1/Slc4a3/Ptger3/Slc4a8/Psen1/Abcc5/Gabbr1/Abcg3/Cacna1a/Lrrc8c/Cacnb4/Myc	32
GO:0014013	regulation of gliogenesis	BP	0.124	0.000474	0.00343	2.46	0.00222	Ptprz1/Mdk/Nog/Igf1/Tert/Dab1/Id4/Serpine2/Lrp2/Daam2/Bin1/Zcchc24/Ptn/Enpp2/Myc/Zfp365	16
GO:0003407	neural retina development	BP	0.148	0.000475	0.00343	2.46	0.00222	Ihh/Sdk2/Arl6/Obsl1/Ptprm/Thy1/Rp1/Hipk2/Rorb/Fat3/Ptn/Hipk1	12
GO:0019228	neuronal action potential	BP	0.184	0.000481	0.00347	2.46	0.00225	Kcnd2/P2rx2/Scn1a/Scn2a/Grik2/Kcnma1/Kcnc4/Cacna1h/Scn3a	9
GO:0046633	alpha-beta T cell proliferation	BP	0.184	0.000481	0.00347	2.46	0.00225	Cd44/Mapk8ip1/Dock2/Btla/Xcl1/Zap70/Il12rb1/Myc/Rasal3	9
GO:0048675	axon extension	BP	0.12	0.000486	0.0035	2.46	0.00227	Map2/Sema5a/Sema5b/Nrp1/Sema7a/Fn1/Cxcl12/Edn3/Ndn/Nlgn3/Apoe/Ednra/Sema3g/Sema6a/Ulk2/Slit3/Draxin	17
GO:0001892	embryonic placenta development	BP	0.128	0.000494	0.00355	2.45	0.0023	Lef1/Itga4/Slc8a1/Vash1/Syde1/Prdm1/Pcdh12/Cdkn1c/Igf2/Snai1/Pkd1/Pkd2/Vash2/Bmp7/Hey2	15
GO:0030100	regulation of endocytosis	BP	0.101	0.000495	0.00355	2.45	0.0023	Angpt1/Nlgn1/Drd4/Gpc3/Lrrk2/Cdh13/Lrp2/Epha3/Apoe/Magi2/Syt7/Sele/Hip1/Bin1/Nckap1l/Arrb1/Arrb2/Dlg4/Apln/Smpd1/Cav1/Nr1h3/Pld2/Ankrd13a	24
GO:0018105	peptidyl-serine phosphorylation	BP	0.0914	0.000498	0.00357	2.45	0.00231	Hgf/Sfrp2/Angpt1/Hcls1/Cd44/Lrrk2/Pfn2/Prkd1/Tek/Rps6ka2/Ppm1f/Caprin2/Dclk2/Bdkrb2/Pkd1/Hipk2/Rps6ka5/Arrb1/Rassf2/Arrb2/Ttbk2/Akt3/Atp2b4/Lats2/Brsk1/Ulk2/Hipk1/Cav1/Sh2d3c/Mknk2/Camk1	31
GO:0048814	regulation of dendrite morphogenesis	BP	0.14	0.000499	0.00358	2.45	0.00232	Ptprz1/Hecw2/Ptprd/Tbc1d24/Obsl1/Trpc6/Caprin2/Nfatc4/Sarm1/Bhlhb9/Cux2/Numbl/Rap2a	13
GO:0031000	response to caffeine	BP	0.333	0.00051	0.00364	2.44	0.00236	Ryr1/Slc8a1/Selenon/Gstm7/Irs1	5
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	BP	0.333	0.00051	0.00364	2.44	0.00236	Sfrp2/Nkd1/Gpc3/Znrf3/Dact1	5
GO:0071248	cellular response to metal ion	BP	0.112	0.000518	0.0037	2.43	0.0024	Slc13a5/Nlgn1/Syt13/Cpne5/Fn1/Lrrk2/Mef2c/Nptx1/Rasgrp2/Adcy7/Dlg2/Syt7/Nfatc4/Asph/Pkd2/Slc25a23/Dlg4/Smpd1/Kcnh1	19
GO:0060042	retina morphogenesis in camera-type eye	BP	0.146	0.000532	0.00379	2.42	0.00246	Ihh/Sdk2/Arl6/Obsl1/Ptprm/Thy1/Rp1/Hipk2/Rorb/Fat3/Ptn/Hipk1	12
GO:0050818	regulation of coagulation	BP	0.155	0.000548	0.0039	2.41	0.00253	Tfpi/Abat/Serpine2/Procr/Apoe/Pros1/Ptger3/St3gal4/Psen1/Cav1/F2r	11
GO:0001945	lymph vessel development	BP	0.226	0.000555	0.00392	2.41	0.00254	Kdr/Vash1/Vegfc/Tie1/Pkd1/Heg1/Svep1	7
GO:0050951	sensory perception of temperature stimulus	BP	0.226	0.000555	0.00392	2.41	0.00254	Ano1/Cxcl12/Calca/Grik2/Enpp1/Htr2a/Arrb2	7
GO:0086010	membrane depolarization during action potential	BP	0.226	0.000555	0.00392	2.41	0.00254	Cacna1c/Scn4b/Scn1a/Cacna2d1/Scn2a/Cacna1h/Scn3a	7
GO:0099633	protein localization to postsynaptic specialization membrane	BP	0.226	0.000555	0.00392	2.41	0.00254	Gpc6/Nptx1/Dlg2/Nptxr/Magi2/Cacng7/Dlg4	7
GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	BP	0.226	0.000555	0.00392	2.41	0.00254	Gpc6/Nptx1/Dlg2/Nptxr/Magi2/Cacng7/Dlg4	7
GO:1904752	regulation of vascular associated smooth muscle cell migration	BP	0.226	0.000555	0.00392	2.41	0.00254	Ddr2/Drd4/Tert/Myo5a/Mef2c/Adamts1/Pcsk5	7
GO:1903053	regulation of extracellular matrix organization	BP	0.18	0.000562	0.00396	2.4	0.00257	Sema5a/Ddr2/Prdm5/Phldb2/Ets1/Has2/Emilin1/Tie1/Efemp2	9
GO:0050728	negative regulation of inflammatory response	BP	0.118	0.000571	0.00402	2.4	0.00261	Hgf/Acod1/Mdk/Pla2g10/Igf1/Cd44/Ets1/Foxf1/Fndc4/Cdh5/Apoe/Cd200/Tnfaip6/Calcrl/Nr1h3/Spn/Wfdc1	17
GO:0008406	gonad development	BP	0.1	0.000593	0.00417	2.38	0.0027	Sfrp2/Ar/Angpt1/Kdr/Nos3/Fst/Hoxa11/Hoxa10/Mmp2/Icam1/Adamts1/Tcf21/Lrp2/Lfng/Kit/Rhobtb3/Kitl/Arrb1/Tnfaip6/Hoxa9/Arrb2/Stat5b/Osr1/Abcb1a	24
GO:2000116	regulation of cysteine-type endopeptidase activity	BP	0.1	0.000593	0.00417	2.38	0.0027	Hgf/Sfrp2/Igf1/Cd44/Bok/Wdr35/Grin2b/Mical1/Ift57/Wnt9a/Ppm1f/Hip1/Arrb1/Epha7/Dlc1/Arrb2/Asph/Fyn/Nlrp1b/Ccn2/Mgmt/Cyfip2/F2r/Myc	24
GO:0009065	glutamine family amino acid catabolic process	BP	0.261	0.000608	0.00425	2.37	0.00276	Ddah1/Nos3/Asrgl1/Fah/Atp2b4/Prodh	6
GO:0015812	gamma-aminobutyric acid transport	BP	0.261	0.000608	0.00425	2.37	0.00276	Grik1/Abat/Htr1b/Gabbr1/Cacna1a/Cacnb4	6
GO:0050961	detection of temperature stimulus involved in sensory perception	BP	0.261	0.000608	0.00425	2.37	0.00276	Ano1/Cxcl12/Calca/Grik2/Htr2a/Arrb2	6
GO:0034766	negative regulation of ion transmembrane transport	BP	0.131	0.000612	0.00427	2.37	0.00277	Hecw2/Drd4/Dysf/Bin1/Osr1/Pkd2/Rrad/Ptger3/Gnb5/Gstm7/Atp1a2/Sri/Cav1/Twist1	14
GO:0007368	determination of left/right symmetry	BP	0.121	0.000613	0.00428	2.37	0.00277	Ihh/Tbx2/Mef2c/Foxf1/Dnah5/Ift57/Aplnr/Tbx3/Dync2h1/Daam2/Pcsk5/Pkd2/Dync2li1/Psen1/Hand2/Eng	16
GO:0033077	T cell differentiation in thymus	BP	0.137	0.000615	0.00428	2.37	0.00277	Ihh/Cd3g/Gli3/Dock2/Zeb1/Jag2/Cd1d1/Stat5b/Zap70/Il2rg/Spn/Il7r/Bcl11b	13
GO:1901879	regulation of protein depolymerization	BP	0.137	0.000615	0.00428	2.37	0.00277	Map2/Sema5a/Evl/Tmod2/Rp1/Sh3bp1/Scin/Dysf/Asph/Ttbk2/Nes/Plekhh2/Plek	13
GO:0061035	regulation of cartilage development	BP	0.153	0.000619	0.0043	2.37	0.00279	Mdk/Hoxd11/Nog/Pkdcc/Hoxa11/Gli3/Wnt9a/Adamts7/Ltbp3/Ccn2/Mboat2	11
GO:0016331	morphogenesis of embryonic epithelium	BP	0.108	0.000621	0.00431	2.37	0.00279	Sfrp2/Wnt6/Ar/Nog/Zeb2/Ift57/Gdf7/Lrp2/Jag2/Cecr2/Vegfc/Prickle1/Ipmk/Dlc1/Ptch1/Osr1/Rab23/Fzd2/Bmp7/Twist1	20
GO:0035051	cardiocyte differentiation	BP	0.108	0.000621	0.00431	2.37	0.00279	AW551984/Sgcd/Col14a1/Igf1/Adra1a/Slc8a1/Mef2c/Nox4/Tbx3/Ednra/Prickle1/Arrb2/Pi16/Abi3bp/Sgcb/Pdgfrb/Bmp7/Hey2/Hand2/Twist1	20
GO:0030513	positive regulation of BMP signaling pathway	BP	0.195	0.000646	0.00447	2.35	0.0029	Kdr/Rnf165/Gpc3/Zfp423/Cdh5/Kcp/Neo1/Eng	8
GO:0051968	positive regulation of synaptic transmission, glutamatergic	BP	0.195	0.000646	0.00447	2.35	0.0029	Gria4/Nlgn1/Grin2b/Shank2/Tshz3/Nlgn3/Cacng7/Nlgn2	8
GO:0008306	associative learning	BP	0.125	0.000648	0.00448	2.35	0.0029	Cacna1c/Nog/Drd4/B4galt2/Grin2b/Pde1b/Adcy3/Shank2/Cacna1e/Kit/Nlgn3/Ddhd2/Atp1a2/Syngap1/Brsk1	15
GO:0010518	positive regulation of phospholipase activity	BP	0.176	0.000654	0.00451	2.35	0.00292	Adra1a/Itk/Arhgap6/Agtr1a/Sele/Adcyap1r1/Htr2a/Dlc1/Pdgfrb	9
GO:0002260	lymphocyte homeostasis	BP	0.143	0.000665	0.00457	2.34	0.00296	Cd44/Mef2c/Sh2b2/Tnfsf13b/Dock10/Coro1a/Enpp1/Nckap1l/Stat5b/Gimap5/Gimap3/Lat	12
GO:0006809	nitric oxide biosynthetic process	BP	0.143	0.000665	0.00457	2.34	0.00296	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	12
GO:0050848	regulation of calcium-mediated signaling	BP	0.143	0.000665	0.00457	2.34	0.00296	Kdr/Igf1/Drd4/Lrrk2/Slc24a4/Cdh13/Itgal/Cmya5/Atp2b4/Zap70/Cd4/Tbc1d10c	12
GO:0060191	regulation of lipase activity	BP	0.143	0.000665	0.00457	2.34	0.00296	Adra1a/Itk/Arhgap6/Agtr1a/Sele/Adcyap1r1/Htr2a/Hdac9/Dlc1/Angptl4/Pdgfrb/Nr1h3	12
GO:0050868	negative regulation of T cell activation	BP	0.12	0.000666	0.00457	2.34	0.00296	Ihh/Mdk/Cd44/Gli3/Loxl3/H2-Ab1/Btla/Havcr2/Nckap1l/Pde5a/H2-Aa/Dlg5/Gimap5/Gimap3/Spn/Lax1	16
GO:0002573	myeloid leukocyte differentiation	BP	0.0992	0.000668	0.00457	2.34	0.00296	Lef1/Cd109/Hcls1/Gpc3/Mef2c/Inpp4b/Lrrc17/Plcb1/Calca/Kit/Enpp1/Tnfrsf11b/Zbtb46/Kitl/Tal1/Tnfaip6/Rassf2/Nrros/Gimap5/Gimap3/Psen1/Batf/Cd4/Myc	24
GO:0051150	regulation of smooth muscle cell differentiation	BP	0.219	0.000682	0.00466	2.33	0.00302	Zeb1/Tshz3/Kit/Cth/Rbpms2/Efemp2/Eng	7
GO:0060977	coronary vasculature morphogenesis	BP	0.219	0.000682	0.00466	2.33	0.00302	Angpt1/Sgcd/Nrp1/Lrp2/Pdgfrb/Hey2/Hand2	7
GO:0050680	negative regulation of epithelial cell proliferation	BP	0.11	0.000692	0.00472	2.33	0.00306	Sfrp2/Ar/Cd109/Gkn3/Gpc3/Mef2c/Cxcr3/Vash1/Ptprm/Ift57/Cdkn1c/Apoe/Klf9/Ptch1/Aqp11/Ptn/Cav1/Wfdc1/Eng	19
GO:0043954	cellular component maintenance	BP	0.151	0.000698	0.00474	2.32	0.00307	Epb41l3/Fermt2/Grin2b/Shank2/Apoe/Erc2/Fyn/Syngap1/Zmynd8/Cldn1/F2r	11
GO:0046637	regulation of alpha-beta T cell differentiation	BP	0.151	0.000698	0.00474	2.32	0.00307	Ihh/Cd83/Gli3/Loxl3/Prdm1/Cd1d1/Nckap1l/Gimap5/Zap70/Gimap3/Il2rg	11
GO:0048678	response to axon injury	BP	0.151	0.000698	0.00474	2.32	0.00307	Gap43/Mmp2/Matn2/Enpp1/Rtn4rl1/Neo1/Sarm1/Xylt1/Dpysl3/Ptn/Nrep	11
GO:0001947	heart looping	BP	0.161	0.000699	0.00474	2.32	0.00307	Ihh/Tbx2/Mef2c/Ift57/Aplnr/Tbx3/Pkd2/Psen1/Hand2/Eng	10
GO:0051058	negative regulation of small GTPase mediated signal transduction	BP	0.161	0.000699	0.00474	2.32	0.00307	Adra1a/Rasa3/Arhgap25/Sh3bp1/Rasip1/Arap3/Heg1/Dlc1/Syngap1/Rasal3	10
GO:0051963	regulation of synapse assembly	BP	0.124	0.000707	0.00479	2.32	0.0031	Gpc6/Ptprd/St8sia2/Nlgn1/Lrrc4b/Mef2c/Nptx1/Adgrl1/Slitrk3/Nlgn3/Epha7/Bhlhb9/Cux2/Dlg5/Nlgn2	15
GO:0072521	purine-containing compound metabolic process	BP	0.0867	0.000708	0.00479	2.32	0.0031	Ttr/Nme4/Acsl6/Igf1/Hmgcs2/Nos3/Acacb/Lrrk2/Adcy3/Gamt/Them5/Gucy1b1/Gucy1a1/Adcy4/Dhtkd1/Adcy7/Enpp1/Lacc1/Htr2a/Acot7/Zbtb20/Pde5a/Rab23/Acsl1/Impdh1/Dpyd/Psen1/Pid1/Pfkm/Cacnb4/Myc/Papss2/Suclg2/Acot6	34
GO:0006865	amino acid transport	BP	0.112	0.000713	0.0048	2.32	0.00311	Slc1a3/Grik1/Abat/Slc7a2/Grin2b/Slc36a4/Htr1b/Slc6a15/Sfxn5/Slc38a1/Nfkbie/Slc7a7/Psen1/Gabbr1/Cacna1a/Lrrc8c/Cacnb4/Myc	18
GO:0044065	regulation of respiratory system process	BP	0.312	0.000713	0.0048	2.32	0.00311	Nlgn1/Tshz3/Nlgn3/Atp1a2/Nlgn2	5
GO:0060046	regulation of acrosome reaction	BP	0.312	0.000713	0.0048	2.32	0.00311	Pla2g10/Spink1/Plcb1/Cacna1h/Pkdrej	5
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	BP	0.312	0.000713	0.0048	2.32	0.00311	Plxnb1/Nrp1/Mef2c/Plxnd1/Ednra	5
GO:0045619	regulation of lymphocyte differentiation	BP	0.104	0.000722	0.00485	2.31	0.00314	Ihh/Mdk/Lef1/Cd83/Cd44/Pik3r6/Gli3/Flt3/Loxl3/Zeb1/Prdm1/Cd1d1/Sox12/Nckap1l/Stat5b/H2-Aa/Gimap5/Zap70/Gimap3/Il2rg/Il7r	21
GO:0032411	positive regulation of transporter activity	BP	0.119	0.000723	0.00485	2.31	0.00314	Tcaf1/Drd4/Cacna2d1/Myo5a/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Ednra/Stac2/Asph/Pkd2/Gstm7/Abcb1a/Cacnb4	16
GO:1903038	negative regulation of leukocyte cell-cell adhesion	BP	0.116	0.000724	0.00485	2.31	0.00314	Ihh/Mdk/Cd44/Cxcl12/Gli3/Loxl3/H2-Ab1/Btla/Havcr2/Nckap1l/Pde5a/H2-Aa/Dlg5/Gimap5/Gimap3/Spn/Lax1	17
GO:0007548	sex differentiation	BP	0.0915	0.000738	0.00494	2.31	0.0032	Tex15/Stra6/Sfrp2/Ar/Angpt1/Kdr/Nos3/Fst/Hoxa11/Hoxa10/Mmp2/Icam1/Adamts1/Tcf21/Lrp2/Lfng/Kit/Tbx3/Rhobtb3/Kitl/Arrb1/Tnfaip6/Hoxa9/Smad9/Arrb2/Stat5b/Osr1/Abcb1a/Lhfpl2	29
GO:0034103	regulation of tissue remodeling	BP	0.141	0.000741	0.00495	2.31	0.00321	Mdk/Ddr2/Inpp4b/Erg/Calca/Tnfrsf11b/Cd38/Syt7/Ltbp3/Abi3bp/Def8/Hand2	12
GO:0002028	regulation of sodium ion transport	BP	0.134	0.000751	0.00501	2.3	0.00325	Hecw2/Slc8a1/Nos3/Scn4b/Drd4/Fxyd5/Serpine2/Plcb1/Osr1/Akt3/Atp2b4/Atp1a2/Mllt6	13
GO:0002718	regulation of cytokine production involved in immune response	BP	0.134	0.000751	0.00501	2.3	0.00325	Angpt1/Sema7a/Tek/Gprc5b/Tril/Kit/Cd226/Lacc1/Xcl1/Gimap5/Gimap3/Clnk/Cd96	13
GO:0032715	negative regulation of interleukin-6 production	BP	0.173	0.000757	0.00504	2.3	0.00326	Hgf/Flt3/Il27ra/Havcr2/Cd200/Nckap1l/Arrb1/Arrb2/Cd84	9
GO:1902622	regulation of neutrophil migration	BP	0.173	0.000757	0.00504	2.3	0.00326	Mdk/Jam3/Ednra/Dysf/Nckap1l/Xcl1/Tnfaip6/Ptger3/Mpp1	9
GO:0014046	dopamine secretion	BP	0.19	0.000765	0.00507	2.3	0.00328	Syt13/Abat/Myo5a/Cxcl12/Htr1b/Syt7/Htr2a/Gabbr1	8
GO:0014059	regulation of dopamine secretion	BP	0.19	0.000765	0.00507	2.3	0.00328	Syt13/Abat/Myo5a/Cxcl12/Htr1b/Syt7/Htr2a/Gabbr1	8
GO:0031076	embryonic camera-type eye development	BP	0.19	0.000765	0.00507	2.3	0.00328	Stra6/Ihh/Tbx2/Zeb1/Hipk2/Hipk1/Bmp7/Twist1	8
GO:0070507	regulation of microtubule cytoskeleton organization	BP	0.112	0.000767	0.00508	2.29	0.00329	Map2/Phldb2/Mpdz/Gnai1/Cdh5/Map9/Epha3/Rp1/Tubb4a/Dysf/Pkd1/Nin/Slain1/Ttbk2/Cep97/Mapre2/Cav1/Tppp	18
GO:0002693	positive regulation of cellular extravasation	BP	0.25	0.000777	0.00513	2.29	0.00332	Mdk/Icam1/Jam3/Thy1/Pecam1/Ptger3	6
GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	BP	0.25	0.000777	0.00513	2.29	0.00332	Ptp4a3/Jcad/Tcf4/Atp2b4/Adgra2/Sema6a	6
GO:0009064	glutamine family amino acid metabolic process	BP	0.159	0.000796	0.00523	2.28	0.00339	Ddah1/Nos3/Asrgl1/Fah/Amdhd1/Phgdh/Atp2b4/Slc7a7/Asl/Prodh	10
GO:0035306	positive regulation of dephosphorylation	BP	0.159	0.000796	0.00523	2.28	0.00339	Npnt/Mef2c/Itga1/Cdh5/Ppp1r16b/Magi2/Dlc1/Smpd1/Pdgfrb/Plek	10
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	BP	0.159	0.000796	0.00523	2.28	0.00339	Calca/Htr1b/Aplnr/Arrb1/Arrb2/Ptger3/Atp2b4/Apln/Pld2/Plek	10
GO:0044282	small molecule catabolic process	BP	0.0898	0.000813	0.00534	2.27	0.00346	Ddah1/Npl/Abat/Nos3/Acacb/Cbs/Asrgl1/Inpp4b/Fah/Amdhd1/Bdh2/Hdc/Apoe/Bpnt1/Echs1/Acot7/Cyp46a1/Sord/Atp2b4/Abcd2/Dpyd/Dhdh/Lipe/Sardh/Prodh/Pfkm/Twist1/Abhd3/Echdc2/Irs1	30
GO:0006469	negative regulation of protein kinase activity	BP	0.103	0.000821	0.00538	2.27	0.00349	Sfrp2/Slc8a1/Ptpro/Mapk8ip1/Slc8a3/Pkia/Thy1/Ppm1f/Cdkn1c/Apoe/Rasip1/Ppm1e/Pkib/Heg1/Lats2/Smpd1/Psen1/Cav1/Bmp7/Prkar1b/Lax1	21
GO:0060415	muscle tissue morphogenesis	BP	0.14	0.000824	0.0054	2.27	0.0035	Col11a1/Angpt1/Nog/Lrp2/Ccm2l/Ednra/Myl3/Heg1/Fzd2/Efemp2/Hey2/Eng	12
GO:0042632	cholesterol homeostasis	BP	0.133	0.000829	0.0054	2.27	0.0035	Apob/Pla2g10/Cyp7b1/Nr5a2/Soat1/Tsku/Apoe/Hdac9/Abca5/Abcg1/Cav1/Nr1h3/Abcg4	13
GO:0009187	cyclic nucleotide metabolic process	BP	0.212	0.00083	0.0054	2.27	0.0035	Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7/Pde5a/Cacnb4	7
GO:0048566	embryonic digestive tract development	BP	0.212	0.00083	0.0054	2.27	0.0035	Stra6/Ihh/Pkdcc/Foxf1/Tcf21/Gli3/Pcsk5	7
GO:0048841	regulation of axon extension involved in axon guidance	BP	0.212	0.00083	0.0054	2.27	0.0035	Sema5a/Sema5b/Nrp1/Sema7a/Cxcl12/Sema3g/Sema6a	7
GO:1904646	cellular response to amyloid-beta	BP	0.212	0.00083	0.0054	2.27	0.0035	Itga4/Igf1/Cacna2d1/Icam1/Fyn/Psen1/Cacna1a	7
GO:0051494	negative regulation of cytoskeleton organization	BP	0.108	0.000854	0.00555	2.26	0.0036	Kank4/Map2/Evl/Phldb2/Tmod2/Pfn2/Cdh5/Coro1a/Rp1/Arhgap6/Tubb4a/Pecam1/Tmeff2/Scin/Dysf/Dlc1/Arhgap28/Ttbk2/Plekhh2	19
GO:0043392	negative regulation of DNA binding	BP	0.17	0.000874	0.00565	2.25	0.00366	Lef1/Zfp462/Twist2/Habp4/Zfp90/Psen1/Sri/Hey2/Hand2	9
GO:0045907	positive regulation of vasoconstriction	BP	0.17	0.000874	0.00565	2.25	0.00366	Adra1a/Icam1/Wdr35/Cd38/Htr2a/Pde5a/Ptger3/Cav1/F2r	9
GO:0046638	positive regulation of alpha-beta T cell differentiation	BP	0.17	0.000874	0.00565	2.25	0.00366	Ihh/Cd83/Gli3/Cd1d1/Nckap1l/Gimap5/Zap70/Gimap3/Il2rg	9
GO:0060412	ventricular septum morphogenesis	BP	0.17	0.000874	0.00565	2.25	0.00366	Wnt11/Nog/Nos3/Aplnr/Tbx3/Heyl/Fzd2/Hey2/Slit3	9
GO:0070169	positive regulation of biomineral tissue development	BP	0.17	0.000874	0.00565	2.25	0.00366	Wnt6/Pkdcc/Slc8a1/Mef2c/Osr2/Nell1/Osr1/Ptn/Bmp7	9
GO:0003253	cardiac neural crest cell migration involved in outflow tract morphogenesis	BP	0.4	0.000884	0.00567	2.25	0.00368	Ednra/Bmp7/Hand2/Twist1	4
GO:0006527	arginine catabolic process	BP	0.4	0.000884	0.00567	2.25	0.00368	Ddah1/Nos3/Fah/Atp2b4	4
GO:0060385	axonogenesis involved in innervation	BP	0.4	0.000884	0.00567	2.25	0.00368	Itga4/Nrp1/Nptx1/Ednra	4
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	BP	0.4	0.000884	0.00567	2.25	0.00368	Slc8a1/Gjc1/Sri/Cav1	4
GO:0097119	postsynaptic density protein 95 clustering	BP	0.4	0.000884	0.00567	2.25	0.00368	Nlgn1/Cdh2/Zmynd8/Nlgn2	4
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	BP	0.4	0.000884	0.00567	2.25	0.00368	Ppp1r16b/Aplnr/Jcad/Agtr1a	4
GO:0062197	cellular response to chemical stress	BP	0.0893	0.000894	0.00573	2.24	0.00372	Cyp1b1/Hgf/Ddr2/Slc8a1/Nos3/Lrrk2/Mmp2/Prkd1/Tbc1d24/Trpc6/Scn2a/Aifm2/Prr5l/Ednra/Dysf/Bdkrb2/Selenon/Pkd2/Net1/Fyn/Mgat3/Slc25a23/Stx2/Pdgfrb/Meak7/Pde8a/Cav1/Lrrc8c/Setx/Fbln5	30
GO:0030501	positive regulation of bone mineralization	BP	0.186	9e-04	0.00575	2.24	0.00373	Pkdcc/Slc8a1/Mef2c/Osr2/Nell1/Osr1/Ptn/Bmp7	8
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	BP	0.186	9e-04	0.00575	2.24	0.00373	Cxcr3/Thy1/Aplnr/Ednra/Pkd2/Gstm7/Sri/F2r	8
GO:0086002	cardiac muscle cell action potential involved in contraction	BP	0.186	9e-04	0.00575	2.24	0.00373	Cacna1c/Kcnd3/Scn4b/Scn1a/Cacna2d1/Ank2/Bin1/Cav1	8
GO:0008347	glial cell migration	BP	0.156	0.000903	0.00575	2.24	0.00373	Ptprz1/Apcdd1/Cspg4/Fn1/Dab1/Gli3/Ndn/Matn2/Enpp1/Vcan	10
GO:0050435	amyloid-beta metabolic process	BP	0.156	0.000903	0.00575	2.24	0.00373	Igf1/Aph1b/Rtn1/Slc2a13/Mme/Apoe/Bin1/Abcg1/Mgat3/Psen1	10
GO:0060193	positive regulation of lipase activity	BP	0.156	0.000903	0.00575	2.24	0.00373	Adra1a/Itk/Arhgap6/Agtr1a/Sele/Adcyap1r1/Htr2a/Dlc1/Pdgfrb/Nr1h3	10
GO:0006672	ceramide metabolic process	BP	0.131	0.000913	0.00579	2.24	0.00375	St8sia2/St8sia4/Agk/Sptlc3/Cers4/St3gal2/Plpp3/St6galnac4/Degs2/St8sia6/Plpp1/St6galnac6/Smpd1	13
GO:0055092	sterol homeostasis	BP	0.131	0.000913	0.00579	2.24	0.00375	Apob/Pla2g10/Cyp7b1/Nr5a2/Soat1/Tsku/Apoe/Hdac9/Abca5/Abcg1/Cav1/Nr1h3/Abcg4	13
GO:0002286	T cell activation involved in immune response	BP	0.121	0.000914	0.00579	2.24	0.00375	Mdk/Lef1/Icam1/Eif2ak4/Loxl3/Itgal/Cracr2a/Havcr2/Nckap1l/Psen1/Apbb1ip/Rab27a/Batf/Spn/Ly9	15
GO:0032410	negative regulation of transporter activity	BP	0.138	0.000915	0.00579	2.24	0.00375	Hecw2/Drd4/Dysf/Osr1/Pkd2/Rrad/Gnb5/Gstm7/Atp1a2/Sri/Cav1/Twist1	12
GO:0031623	receptor internalization	BP	0.117	0.000921	0.00582	2.23	0.00377	Angpt1/Drd4/Calca/Htr1b/Magi2/Sele/Arrb1/Cacng7/Arrb2/Calcrl/Dlg4/Ptger3/Apln/Cav1/Pld2/Ankrd13a	16
GO:0046395	carboxylic acid catabolic process	BP	0.1	0.000925	0.00584	2.23	0.00379	Ddah1/Npl/Abat/Nos3/Acacb/Cbs/Asrgl1/Fah/Amdhd1/Bdh2/Hdc/Echs1/Acot7/Atp2b4/Abcd2/Lipe/Sardh/Prodh/Twist1/Abhd3/Echdc2/Irs1	22
GO:0001845	phagolysosome assembly	BP	0.294	0.00097	0.00611	2.21	0.00396	Rab34/Srpx/Coro1a/Syt7/Rab20	5
GO:0097094	craniofacial suture morphogenesis	BP	0.294	0.00097	0.00611	2.21	0.00396	Mmp16/Gli3/Frem1/Rab23/Twist1	5
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	BP	0.294	0.00097	0.00611	2.21	0.00396	Plxnb1/Nrp1/Mef2c/Plxnd1/Ednra	5
GO:0007620	copulation	BP	0.24	0.000982	0.00616	2.21	0.00399	Ar/Abat/Drd4/Ednrb/Serpine2/Ednra	6
GO:0035988	chondrocyte proliferation	BP	0.24	0.000982	0.00616	2.21	0.00399	Ihh/Mmp16/Lef1/Ddr2/Stc1/Ccn2	6
GO:2000311	regulation of AMPA receptor activity	BP	0.24	0.000982	0.00616	2.21	0.00399	Nlgn1/Mef2c/Nlgn3/Prrt1/Cacng7/Nlgn2	6
GO:0046847	filopodium assembly	BP	0.145	0.000985	0.00617	2.21	0.004	Gap43/Nlgn1/Nrp1/Sh3bp1/Daam2/Fgd1/Palm/Dpysl3/Itgb4/Zmynd8/Fgd2	11
GO:0099054	presynapse assembly	BP	0.167	0.001	0.00628	2.2	0.00407	Gpc6/Ptprd/Nlgn1/Lrrc4b/Slitrk3/Nlgn3/Pcdh17/Lrp4/Nlgn2	9
GO:0016054	organic acid catabolic process	BP	0.0995	0.00104	0.00651	2.19	0.00422	Ddah1/Npl/Abat/Nos3/Acacb/Cbs/Asrgl1/Fah/Amdhd1/Bdh2/Hdc/Echs1/Acot7/Atp2b4/Abcd2/Lipe/Sardh/Prodh/Twist1/Abhd3/Echdc2/Irs1	22
GO:0010464	regulation of mesenchymal cell proliferation	BP	0.182	0.00105	0.00657	2.18	0.00426	Ihh/Wnt11/Kdr/Foxf1/Zeb1/Ptn/Myc/Irs1	8
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	BP	0.182	0.00105	0.00657	2.18	0.00426	Cacna2d1/Ank2/Cracr2a/Stac2/Asph/Pkd2/Gstm7/Cacnb4	8
GO:0046660	female sex differentiation	BP	0.112	0.00106	0.00657	2.18	0.00426	Stra6/Angpt1/Kdr/Nos3/Fst/Mmp2/Adamts1/Lrp2/Lfng/Kit/Tbx3/Kitl/Arrb1/Tnfaip6/Arrb2/Stat5b/Lhfpl2	17
GO:0051099	positive regulation of binding	BP	0.104	0.00106	0.00657	2.18	0.00426	Igf1/Tert/Lrrk2/Plxnd1/Lfng/Apoe/Caprin2/Pkd1/Hipk2/Arrb1/Cldn5/Mfng/Psen1/Hipk1/Cav1/Dact1/Gpsm1/Hand2/Myc/Twist1	20
GO:0010876	lipid localization	BP	0.0824	0.00109	0.00674	2.17	0.00437	Apob/Stra6/Nme4/Acsl6/Pla2g10/Acacb/Drd4/Vstm2a/Mest/Soat1/Abcg2/Rbp7/Osbp2/Pltp/Selenom/Enpp1/Agtr1a/Apoe/Syt7/Dysf/Bdkrb2/Abca5/Abcg1/Stat5b/Abca8b/Abcd2/Acsl1/Atp10a/Abcb1a/Osbpl1a/Cav1/Nr1h3/Xkr5/Atp8b4/Prelid3a/Abcg4/Cds1	37
GO:0009410	response to xenobiotic stimulus	BP	0.0892	0.00109	0.00676	2.17	0.00438	Kcnk3/Cyp1b1/Slc1a3/Sfrp2/Kdr/Adra1a/Abat/Mmp2/Mef2c/Shank2/Ptprm/Htr1b/Fmo1/Ppm1f/Cd38/Igf2/Ppm1e/Nckap1l/Htr2a/Cyp46a1/Acsl1/Gstm7/Dpyd/Gstm1/Abcb1a/Sult1a1/Bche/Myc/Rap2a	29
GO:0033135	regulation of peptidyl-serine phosphorylation	BP	0.108	0.0011	0.00679	2.17	0.0044	Hgf/Sfrp2/Angpt1/Hcls1/Cd44/Pfn2/Prkd1/Tek/Ppm1f/Caprin2/Bdkrb2/Arrb1/Rassf2/Arrb2/Atp2b4/Cav1/Sh2d3c/Camk1	18
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	BP	0.129	0.0011	0.00683	2.17	0.00442	Adra1a/Npr3/Ednrb/Ano1/Lpar4/Calca/Pth1r/Agtr1a/Ednra/Htr2a/Plcb2/Ptger3/F2r	13
GO:0045637	regulation of myeloid cell differentiation	BP	0.0991	0.00111	0.00683	2.17	0.00442	Lef1/P4htm/Hcls1/Ets1/Mef2c/Inpp4b/Lrrc17/Calca/Tnfrsf11b/Gpr171/Zbtb46/Scin/Nckap1l/Kitl/Tal1/Tnfaip6/Hoxa9/Twist2/Rassf2/Stat5b/Cd4/Myc	22
GO:0048469	cell maturation	BP	0.0991	0.00111	0.00683	2.17	0.00442	Epha8/Ihh/Pla2g10/Kdr/Spink1/Cspg4/Lrrk2/Ednrb/Gdf11/Flvcr1/Plcb1/Calca/Rps6ka2/Pth1r/Dlg2/Cdkn1c/Nfasc/Kcnma1/Ednra/Tal1/Lhx6/Septin4	22
GO:0030010	establishment of cell polarity	BP	0.111	0.00114	0.00701	2.15	0.00454	Ankfn1/Map2/Fez1/Foxf1/Jam3/Dock2/Myo9a/Cdh5/Msn/Frmd4b/Ubxn2b/Prickle2/Sh3bp1/Pkd1/Pard3b/Frmd4a/Brsk1	17
GO:0010712	regulation of collagen metabolic process	BP	0.164	0.00115	0.00707	2.15	0.00458	Ihh/Ddr2/Fn1/Emilin1/Arrb2/Ccn2/Pdgfrb/Cygb/F2r	9
GO:0055010	ventricular cardiac muscle tissue morphogenesis	BP	0.164	0.00115	0.00707	2.15	0.00458	Col11a1/Nog/Lrp2/Ccm2l/Ednra/Myl3/Heg1/Hey2/Eng	9
GO:0001818	negative regulation of cytokine production	BP	0.0912	0.00115	0.00707	2.15	0.00458	Hgf/Acod1/Angpt1/Lef1/Wnt11/Pla2g10/Cd83/Igf1/Fn1/Flt3/Adcy7/Il27ra/Tsku/Havcr2/Cd200/Nckap1l/Arrb1/Hdac9/Twist2/Mapkbp1/Arrb2/Cd84/Gimap5/Abcd2/Gimap3/Cd96/Twist1	27
GO:0031532	actin cytoskeleton reorganization	BP	0.123	0.00115	0.00707	2.15	0.00458	Hmcn1/Mdk/Nrp1/Thsd7b/Tek/Syde1/Kit/Esam/Parvg/Efs/Carmil3/Parvb/Plek/Rap2a	14
GO:0002715	regulation of natural killer cell mediated immunity	BP	0.152	0.00115	0.00707	2.15	0.00458	Pik3r6/Cd226/Havcr2/Igf2/Arrb2/Stat5b/Gimap5/Gimap3/Clnk/Cd96	10
GO:0002720	positive regulation of cytokine production involved in immune response	BP	0.152	0.00115	0.00707	2.15	0.00458	Sema7a/Tek/Gprc5b/Kit/Cd226/Lacc1/Xcl1/Gimap5/Gimap3/Clnk	10
GO:0001573	ganglioside metabolic process	BP	0.231	0.00122	0.00749	2.13	0.00485	St8sia2/St8sia4/St3gal2/St6galnac4/St8sia6/St6galnac6	6
GO:2000050	regulation of non-canonical Wnt signaling pathway	BP	0.231	0.00122	0.00749	2.13	0.00485	Sfrp2/Nkd1/Gpc3/Znrf3/Daam2/Dact1	6
GO:0032413	negative regulation of ion transmembrane transporter activity	BP	0.141	0.00123	0.00749	2.13	0.00485	Hecw2/Drd4/Dysf/Osr1/Pkd2/Rrad/Gnb5/Gstm7/Atp1a2/Sri/Cav1	11
GO:0046209	nitric oxide metabolic process	BP	0.133	0.00124	0.00756	2.12	0.0049	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	12
GO:0009855	determination of bilateral symmetry	BP	0.113	0.00125	0.00764	2.12	0.00495	Ihh/Tbx2/Mef2c/Foxf1/Dnah5/Ift57/Aplnr/Tbx3/Dync2h1/Daam2/Pcsk5/Pkd2/Dync2li1/Psen1/Hand2/Eng	16
GO:0051146	striated muscle cell differentiation	BP	0.0884	0.00125	0.00764	2.12	0.00495	AW551984/Sgcd/Col14a1/Ryr1/Igf1/Adra1a/Slc8a1/P2rx2/Tmod2/Cdh2/Mef2c/Cxcl12/Hopx/Nox4/Tbx3/Igf2/Dysf/Hdac9/Flnc/Neo1/Selenon/Arrb2/Pi16/Sgcb/Plekho1/Pdgfrb/Hacd1/Hey2/Hand2	29
GO:0048640	negative regulation of developmental growth	BP	0.117	0.00127	0.00771	2.11	0.00499	Map2/Sema5a/H19/Nog/Sema5b/Nrp1/Nkd1/Sema7a/Sema3g/Epha7/Ptch1/Pi16/Sema6a/Ulk2/Draxin	15
GO:0007614	short-term memory	BP	0.278	0.00129	0.00783	2.11	0.00507	Mdk/Aph1b/Drd4/Pde5a/Cux2	5
GO:0070486	leukocyte aggregation	BP	0.278	0.00129	0.00783	2.11	0.00507	Cd44/Has2/Msn/Bmp7/Jam2	5
GO:0060350	endochondral bone morphogenesis	BP	0.149	0.0013	0.00787	2.1	0.0051	Ihh/Mmp16/Hoxd11/Thbs3/Cbs/Hoxa11/Mef2c/Stc1/Col13a1/Enpp1	10
GO:1903539	protein localization to postsynaptic membrane	BP	0.161	0.00131	0.00795	2.1	0.00515	Gpc6/Stx1b/Nptx1/Dlg2/Nptxr/Magi2/Nsg1/Cacng7/Dlg4	9
GO:0001704	formation of primary germ layer	BP	0.126	0.00132	0.008	2.1	0.00518	Sfrp2/Lef1/Wnt11/Nog/Hoxa11/Fn1/Foxf1/Col5a2/Snai1/Tal1/Ets2/Kif16b/Bmp7	13
GO:0021761	limbic system development	BP	0.126	0.00132	0.008	2.1	0.00518	Mdk/Lef1/Zeb2/Nrp1/Dab1/Id4/Gli3/Tsku/Tbx3/Ndnf/Dclk2/Atp1a2/Bbs1	13
GO:0002399	MHC class II protein complex assembly	BP	0.364	0.00134	0.00801	2.1	0.00519	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0002503	peptide antigen assembly with MHC class II protein complex	BP	0.364	0.00134	0.00801	2.1	0.00519	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0035336	long-chain fatty-acyl-CoA metabolic process	BP	0.364	0.00134	0.00801	2.1	0.00519	Acsl6/Them5/Acot7/Acsl1	4
GO:0036302	atrioventricular canal development	BP	0.364	0.00134	0.00801	2.1	0.00519	Tbx2/Has2/Tbx3/Eng	4
GO:0061299	retina vasculature morphogenesis in camera-type eye	BP	0.364	0.00134	0.00801	2.1	0.00519	Ndp/Cyp1b1/Nrp1/Arhgef15	4
GO:0071415	cellular response to purine-containing compound	BP	0.364	0.00134	0.00801	2.1	0.00519	Ryr1/Slc8a1/Selenon/Gstm7	4
GO:0072075	metanephric mesenchyme development	BP	0.364	0.00134	0.00801	2.1	0.00519	Tcf21/Osr1/Bmp7/Myc	4
GO:0030041	actin filament polymerization	BP	0.107	0.00135	0.00806	2.09	0.00522	Kank4/Evl/Hcls1/Tmod2/Pfn2/Icam1/Catip/Coro1a/Esam/Daam2/Pecam1/Scin/Bin1/Nckap1l/Arhgap28/Cdc42ep5/Cyfip2/Pstpip1	18
GO:0009799	specification of symmetry	BP	0.113	0.00135	0.00808	2.09	0.00524	Ihh/Tbx2/Mef2c/Foxf1/Dnah5/Ift57/Aplnr/Tbx3/Dync2h1/Daam2/Pcsk5/Pkd2/Dync2li1/Psen1/Hand2/Eng	16
GO:0071277	cellular response to calcium ion	BP	0.139	0.00136	0.00814	2.09	0.00528	Nlgn1/Syt13/Cpne5/Mef2c/Rasgrp2/Syt7/Asph/Pkd2/Slc25a23/Smpd1/Kcnh1	11
GO:0043297	apical junction assembly	BP	0.132	0.00137	0.00814	2.09	0.00528	Wnt11/Cldn8/Cdh5/Abi2/Esam/Pecam1/Snai1/Nphp1/Cldn5/Dlg5/Pdcd6ip/Cldn1	12
GO:0035710	CD4-positive, alpha-beta T cell activation	BP	0.121	0.00137	0.00814	2.09	0.00528	Lef1/Cd83/Cd44/Loxl3/Cracr2a/Nckap1l/Xcl1/Satb1/Gimap5/Gimap3/Il2rg/Batf/Spn/Ly9	14
GO:0015850	organic hydroxy compound transport	BP	0.0941	0.00138	0.00822	2.09	0.00533	Apob/Stra6/Maob/Slc6a2/Syt13/Abat/Myo5a/Cxcl12/Slc2a13/Htr1b/Selenom/Cadps/Agtr1a/Apoe/Syt7/Htr2a/Abca5/Abcg1/Abca8b/Ptger3/Gabbr1/Nr1h3/Abcg4/Myc	24
GO:0001838	embryonic epithelial tube formation	BP	0.109	0.00141	0.00837	2.08	0.00543	Sfrp2/Wnt6/Nog/Zeb2/Ift57/Gdf7/Lrp2/Cecr2/Prickle1/Ipmk/Dlc1/Ptch1/Osr1/Rab23/Fzd2/Bmp7/Twist1	17
GO:2001258	negative regulation of cation channel activity	BP	0.174	0.00143	0.00848	2.07	0.00549	Drd4/Dysf/Pkd2/Rrad/Gnb5/Gstm7/Sri/Cav1	8
GO:0048169	regulation of long-term neuronal synaptic plasticity	BP	0.194	0.00143	0.00849	2.07	0.0055	Grik1/Kdr/Grin2b/Kit/Grik2/Dlg4/Syngap1	7
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	BP	0.125	0.00145	0.00859	2.07	0.00557	Mdk/Ptprd/Nrp1/Fermt2/Tbc1d24/Has2/Obsl1/Caprin2/Bhlhb9/Net1/Cux2/Enpp2/Numbl	13
GO:0061371	determination of heart left/right asymmetry	BP	0.147	0.00146	0.00864	2.06	0.0056	Ihh/Tbx2/Mef2c/Ift57/Aplnr/Tbx3/Pkd2/Psen1/Hand2/Eng	10
GO:0033673	negative regulation of kinase activity	BP	0.0969	0.00147	0.00873	2.06	0.00565	Sfrp2/Ddr2/Slc8a1/Ptpro/Mapk8ip1/Slc8a3/Pkia/Thy1/Ppm1f/Cdkn1c/Apoe/Rasip1/Ppm1e/Pkib/Heg1/Lats2/Smpd1/Psen1/Cav1/Bmp7/Prkar1b/Lax1	22
GO:0062237	protein localization to postsynapse	BP	0.158	0.00149	0.00881	2.05	0.00571	Gpc6/Stx1b/Nptx1/Dlg2/Nptxr/Magi2/Nsg1/Cacng7/Dlg4	9
GO:0086001	cardiac muscle cell action potential	BP	0.158	0.00149	0.00881	2.05	0.00571	Cacna1c/Kcnd2/Kcnd3/Scn4b/Scn1a/Cacna2d1/Ank2/Bin1/Cav1	9
GO:1900271	regulation of long-term synaptic potentiation	BP	0.158	0.00149	0.00881	2.05	0.00571	Eif2ak4/Mme/Nlgn3/Nrgn/Apoe/Nsg1/Cyp46a1/Ptn/Prkar1b	9
GO:0035050	embryonic heart tube development	BP	0.13	0.0015	0.00882	2.05	0.00572	Ihh/Tbx2/Slc8a1/Mef2c/Ift57/Aplnr/Tbx3/Ednra/Pkd2/Psen1/Hand2/Eng	12
GO:0043367	CD4-positive, alpha-beta T cell differentiation	BP	0.13	0.0015	0.00882	2.05	0.00572	Lef1/Cd83/Loxl3/Cracr2a/Nckap1l/Satb1/Gimap5/Gimap3/Il2rg/Batf/Spn/Ly9	12
GO:2001057	reactive nitrogen species metabolic process	BP	0.13	0.0015	0.00882	2.05	0.00572	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	12
GO:0003176	aortic valve development	BP	0.222	0.00151	0.00882	2.05	0.00572	Nos3/Emilin1/Tie1/Hey2/Slit3/Twist1	6
GO:0014829	vascular associated smooth muscle contraction	BP	0.222	0.00151	0.00882	2.05	0.00572	Slc8a1/Ednrb/Edn3/Cd38/Ednra/Htr2a	6
GO:0016048	detection of temperature stimulus	BP	0.222	0.00151	0.00882	2.05	0.00572	Ano1/Cxcl12/Calca/Grik2/Htr2a/Arrb2	6
GO:0034368	protein-lipid complex remodeling	BP	0.222	0.00151	0.00882	2.05	0.00572	Apob/Pla2g10/Pltp/Apoe/Abca5/Abcg1	6
GO:0034369	plasma lipoprotein particle remodeling	BP	0.222	0.00151	0.00882	2.05	0.00572	Apob/Pla2g10/Pltp/Apoe/Abca5/Abcg1	6
GO:0048843	negative regulation of axon extension involved in axon guidance	BP	0.222	0.00151	0.00882	2.05	0.00572	Sema5a/Sema5b/Nrp1/Sema7a/Sema3g/Sema6a	6
GO:0060004	reflex	BP	0.222	0.00151	0.00882	2.05	0.00572	Npnt/Adra1a/Glrb/Kcnma1/Satb1/Cacna1a	6
GO:0051965	positive regulation of synapse assembly	BP	0.138	0.00151	0.00882	2.05	0.00572	Ptprd/St8sia2/Nlgn1/Lrrc4b/Adgrl1/Slitrk3/Nlgn3/Bhlhb9/Cux2/Dlg5/Nlgn2	11
GO:1903532	positive regulation of secretion by cell	BP	0.0854	0.00152	0.00884	2.05	0.00573	Pla2g10/Igf1/Nlgn1/Abat/Stx1b/Ano1/Grin2b/Cxcl12/Edn3/Rab34/Cadps/Vegfc/Cd38/Syt7/Arrb1/Abcg1/Frmd4a/Ncs1/Cacna1h/Fgr/Apln/Slc4a8/Rab27a/Sri/Gabbr1/Pld2/Pfkm/Golph3l/Pdcd6ip/Nlgn2/Irs1	31
GO:0008361	regulation of cell size	BP	0.0981	0.0016	0.00931	2.03	0.00603	Map2/Sema5a/Sema5b/Slc12a8/Nrp1/Sema7a/Fn1/Cxcl12/Apoe/Kcnma1/Sema3g/Epha7/Slc12a4/Aqp11/Akt3/Sema6a/Ulk2/C1qtnf9/Il7r/Plek/Draxin	21
GO:0007009	plasma membrane organization	BP	0.108	0.00162	0.0094	2.03	0.00609	Ar/Epb41l3/Ank2/Syt7/Tie1/Tmeff2/Dysf/Bin1/Cavin2/Abcd2/Atp10a/Fat4/Stx2/Smpd1/Cav1/Tlcd2/Xkr5	17
GO:0003143	embryonic heart tube morphogenesis	BP	0.145	0.00163	0.00947	2.02	0.00614	Ihh/Tbx2/Mef2c/Ift57/Aplnr/Tbx3/Pkd2/Psen1/Hand2/Eng	10
GO:0099601	regulation of neurotransmitter receptor activity	BP	0.145	0.00163	0.00947	2.02	0.00614	Begain/Nlgn1/Mef2c/Nptx1/Nlgn3/Nptxr/Prrt1/Cacng7/Dlg4/Nlgn2	10
GO:0051650	establishment of vesicle localization	BP	0.105	0.00164	0.00951	2.02	0.00616	Map2/Itga4/Nlgn1/Sec16b/Lrrk2/Myo5a/Ppfia2/Kif1a/Lin7a/5730455P16Rik/Myo1f/Cep19/Arfgap3/Psen1/Rab27a/Map4k2/Pdcd6ip/Kif5a	18
GO:0003016	respiratory system process	BP	0.17	0.00165	0.00953	2.02	0.00617	Nlgn1/Tshz3/Ndn/Jag2/Nlgn3/Selenon/Atp1a2/Nlgn2	8
GO:0043114	regulation of vascular permeability	BP	0.17	0.00165	0.00953	2.02	0.00617	Angpt1/Ddah1/Fermt2/Ptp4a3/Akap12/Cdh5/Apoe/Cldn5	8
GO:0003214	cardiac left ventricle morphogenesis	BP	0.263	0.00168	0.00966	2.02	0.00626	Sfrp2/Foxf1/Cpe/Ednra/Hey2	5
GO:0030011	maintenance of cell polarity	BP	0.263	0.00168	0.00966	2.02	0.00626	Wnt11/Lin7a/Nckap1l/Dlg5/Pdcd6ip	5
GO:0033623	regulation of integrin activation	BP	0.263	0.00168	0.00966	2.02	0.00626	Fermt2/Jam3/Rasip1/Pcsk5/Plek	5
GO:0045821	positive regulation of glycolytic process	BP	0.263	0.00168	0.00966	2.02	0.00626	Igf1/Htr2a/Zbtb20/Psen1/Myc	5
GO:1901550	regulation of endothelial cell development	BP	0.263	0.00168	0.00966	2.02	0.00626	Plcb1/Cdh5/Cldn5/Akap11/S1pr3	5
GO:1903140	regulation of establishment of endothelial barrier	BP	0.263	0.00168	0.00966	2.02	0.00626	Plcb1/Cdh5/Cldn5/Akap11/S1pr3	5
GO:1905874	regulation of postsynaptic density organization	BP	0.263	0.00168	0.00966	2.02	0.00626	Ptprd/Cdh2/Lrrc4b/Nptx1/Zmynd8	5
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	BP	0.189	0.00169	0.00968	2.01	0.00627	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Fzd2/Dact1	7
GO:0086091	regulation of heart rate by cardiac conduction	BP	0.189	0.00169	0.00968	2.01	0.00627	Cacna1c/Kcnd3/Scn4b/Cacna2d1/Ank2/Bin1/Cav1	7
GO:0015872	dopamine transport	BP	0.155	0.00169	0.00968	2.01	0.00627	Slc6a2/Syt13/Abat/Myo5a/Cxcl12/Htr1b/Syt7/Htr2a/Gabbr1	9
GO:1903531	negative regulation of secretion by cell	BP	0.104	0.00175	0.01	2	0.00648	Maob/Abat/Drd4/Myo5a/Foxf1/Edn3/Htr1b/Apoe/Cd200/Nckap1l/Neo1/Frmd4a/Cd84/Ptger3/Gabbr1/Nr1h3/F2r/Irs1	18
GO:0050727	regulation of inflammatory response	BP	0.0855	0.00177	0.0101	2	0.00654	Hgf/Acod1/Mdk/Pla2g10/Igf1/Cd44/Sema7a/Ets1/Lrrk2/Ednrb/Foxf1/Slc7a2/Fndc4/Gprc5b/Cdh5/Bcl6b/Apoe/Lacc1/Ednra/Cd200/Xcl1/Tnfaip6/Stat5b/Pde5a/Nlrp1b/Calcrl/Ptger3/Nr1h3/Spn/Wfdc1	30
GO:0030833	regulation of actin filament polymerization	BP	0.11	0.00181	0.0103	1.99	0.00668	Kank4/Evl/Hcls1/Tmod2/Pfn2/Icam1/Coro1a/Esam/Daam2/Pecam1/Scin/Bin1/Nckap1l/Arhgap28/Cdc42ep5/Cyfip2	16
GO:0048644	muscle organ morphogenesis	BP	0.128	0.00181	0.0103	1.99	0.00668	Col11a1/Angpt1/Nog/Lrp2/Ccm2l/Ednra/Myl3/Heg1/Fzd2/Efemp2/Hey2/Eng	12
GO:0120193	tight junction organization	BP	0.128	0.00181	0.0103	1.99	0.00668	Wnt11/Mpdz/Cldn8/Cdh5/Esam/Pecam1/Snai1/Svep1/Nphp1/Cldn5/Pdcd6ip/Cldn1	12
GO:0048662	negative regulation of smooth muscle cell proliferation	BP	0.143	0.00183	0.0104	1.98	0.00671	Vipr2/Nos3/Npr3/Drd4/Mef2c/Apoe/Rgs5/Efemp2/Apln/Cav1	10
GO:1902017	regulation of cilium assembly	BP	0.143	0.00183	0.0104	1.98	0.00671	Ccdc88a/Adamts16/Kctd17/Rp1/Crocc/Ttbk2/Dzip1/Dync2li1/Cep97/Atmin	10
GO:0003171	atrioventricular valve development	BP	0.214	0.00185	0.0105	1.98	0.00678	Aplnr/Heyl/Dchs1/Hey2/Slit3/Twist1	6
GO:0018126	protein hydroxylation	BP	0.214	0.00185	0.0105	1.98	0.00678	P3h3/P4htm/Fkbp10/P3h1/Asph/Crtap	6
GO:0014015	positive regulation of gliogenesis	BP	0.134	0.00185	0.0105	1.98	0.0068	Ptprz1/Mdk/Nog/Igf1/Serpine2/Lrp2/Bin1/Ptn/Enpp2/Myc/Zfp365	11
GO:2000177	regulation of neural precursor cell proliferation	BP	0.117	0.00189	0.0107	1.97	0.00692	Gli1/Ptprz1/Mdk/Nog/Igf1/Cdh2/Lrrk2/Smarca1/Zfp423/Gli3/Lrp2/Vegfc/Ptn/Nes	14
GO:0030517	negative regulation of axon extension	BP	0.167	0.00189	0.0107	1.97	0.00692	Map2/Sema5a/Sema5b/Nrp1/Sema7a/Sema3g/Sema6a/Draxin	8
GO:0034205	amyloid-beta formation	BP	0.167	0.00189	0.0107	1.97	0.00692	Igf1/Aph1b/Rtn1/Slc2a13/Apoe/Bin1/Abcg1/Psen1	8
GO:0048010	vascular endothelial growth factor receptor signaling pathway	BP	0.167	0.00189	0.0107	1.97	0.00692	Angpt1/Kdr/Nrp1/Prkd1/Tek/Emilin1/Vegfc/Grb10	8
GO:0045778	positive regulation of ossification	BP	0.153	0.00192	0.0107	1.97	0.00696	Pkdcc/Slc8a1/Mef2c/Osr2/Calca/Nell1/Osr1/Ptn/Bmp7	9
GO:1903350	response to dopamine	BP	0.153	0.00192	0.0107	1.97	0.00696	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Palm/Gnb5	9
GO:1903351	cellular response to dopamine	BP	0.153	0.00192	0.0107	1.97	0.00696	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Palm/Gnb5	9
GO:0034333	adherens junction assembly	BP	0.333	0.00193	0.0107	1.97	0.00696	Jam3/Abi2/Dlg5/Hipk1	4
GO:0048251	elastic fiber assembly	BP	0.333	0.00193	0.0107	1.97	0.00696	Emilin1/Ltbp3/Efemp2/Fbln5	4
GO:0060073	micturition	BP	0.333	0.00193	0.0107	1.97	0.00696	Cacna1c/Adra1a/Kcnma1/Ptger3	4
GO:0060536	cartilage morphogenesis	BP	0.333	0.00193	0.0107	1.97	0.00696	Mef2c/Stc1/Snai1/Hand2	4
GO:0070444	oligodendrocyte progenitor proliferation	BP	0.333	0.00193	0.0107	1.97	0.00696	Ptprz1/Nog/Cdh2/Lrp2	4
GO:0070445	regulation of oligodendrocyte progenitor proliferation	BP	0.333	0.00193	0.0107	1.97	0.00696	Ptprz1/Nog/Cdh2/Lrp2	4
GO:0099519	dense core granule cytoskeletal transport	BP	0.333	0.00193	0.0107	1.97	0.00696	Map2/Ppfia2/Kif1a/Kif5a	4
GO:1903911	positive regulation of receptor clustering	BP	0.333	0.00193	0.0107	1.97	0.00696	Tnfaip6/Dlg4/Ptn/Lrp4	4
GO:0006163	purine nucleotide metabolic process	BP	0.084	0.00196	0.0109	1.96	0.00707	Nme4/Acsl6/Igf1/Hmgcs2/Nos3/Acacb/Lrrk2/Adcy3/Them5/Gucy1b1/Gucy1a1/Adcy4/Dhtkd1/Adcy7/Enpp1/Lacc1/Htr2a/Acot7/Zbtb20/Pde5a/Rab23/Acsl1/Impdh1/Psen1/Pid1/Pfkm/Cacnb4/Myc/Papss2/Suclg2/Acot6	31
GO:0030866	cortical actin cytoskeleton organization	BP	0.184	0.00199	0.011	1.96	0.00716	Epb41l3/Nckap1l/Cavin3/Akap11/Pdcd6ip/Fmnl3/Plek	7
GO:0098868	bone growth	BP	0.184	0.00199	0.011	1.96	0.00716	Kdr/Ddr2/Thbs3/Evc/Stc1/Enpp1/Fbln5	7
GO:0001841	neural tube formation	BP	0.112	0.00201	0.0111	1.95	0.00722	Sfrp2/Nog/Zeb2/Ift57/Gdf7/Lrp2/Cecr2/Prickle1/Ipmk/Dlc1/Ptch1/Rab23/Fzd2/Bmp7/Twist1	15
GO:0048332	mesoderm morphogenesis	BP	0.141	0.00203	0.0113	1.95	0.0073	Sfrp2/Lef1/Wnt11/Nog/Hoxa11/Foxf1/Tbx3/Snai1/Tal1/Bmp7	10
GO:0050432	catecholamine secretion	BP	0.141	0.00203	0.0113	1.95	0.0073	Syt13/Abat/Myo5a/Cxcl12/Htr1b/Cadps/Syt7/Htr2a/Ptger3/Gabbr1	10
GO:0072676	lymphocyte migration	BP	0.12	0.00204	0.0113	1.95	0.00733	Itga4/Cyp7b1/Itgb7/Icam1/Cxcr3/Cxcl12/Msn/Itgal/Il27ra/Cd200/Xcl1/Spn/Jam2	13
GO:0046545	development of primary female sexual characteristics	BP	0.116	0.00205	0.0113	1.95	0.00733	Angpt1/Kdr/Nos3/Fst/Mmp2/Adamts1/Lfng/Kit/Kitl/Arrb1/Tnfaip6/Arrb2/Stat5b/Lhfpl2	14
GO:0016485	protein processing	BP	0.0899	0.00208	0.0115	1.94	0.00745	Cpxm2/Ihh/Mmp16/Aph1b/Lrrk2/Serpine2/Gli3/Rps6ka2/Cpe/Mme/Ldlrad3/C1rl/Dync2h1/Pcsk5/C1ra/Ptch1/Asph/Ece2/Adam19/Arxes2/Psen1/Cyfip2/Nkd2/Myc/Prss12	25
GO:0055088	lipid homeostasis	BP	0.102	0.00212	0.0117	1.93	0.00758	Apob/Pla2g10/Cyp7b1/Nr5a2/Soat1/Tsku/Apoe/Hdac9/Abca5/Rcn3/Zbtb20/Abcg1/Angptl4/Abhd8/Cav1/Nr1h3/Tlcd2/Abcg4	18
GO:0032252	secretory granule localization	BP	0.25	0.00216	0.0118	1.93	0.00765	Map2/Myo5a/Ppfia2/Kif1a/Kif5a	5
GO:0045019	negative regulation of nitric oxide biosynthetic process	BP	0.25	0.00216	0.0118	1.93	0.00765	Wdr35/Atp2b4/Gimap5/Gimap3/Cav1	5
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	BP	0.25	0.00216	0.0118	1.93	0.00765	Ano1/Cxcl12/Calca/Htr2a/Arrb2	5
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	BP	0.25	0.00216	0.0118	1.93	0.00765	Scn1a/Grin2b/Cxcl12/Htr2a/Fyn	5
GO:1903236	regulation of leukocyte tethering or rolling	BP	0.25	0.00216	0.0118	1.93	0.00765	Itga4/Chst2/Cxcl12/Sele/St3gal4	5
GO:1904406	negative regulation of nitric oxide metabolic process	BP	0.25	0.00216	0.0118	1.93	0.00765	Wdr35/Atp2b4/Gimap5/Gimap3/Cav1	5
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	BP	0.25	0.00216	0.0118	1.93	0.00765	Ddr2/Tert/Myo5a/Adamts1/Pcsk5	5
GO:0042987	amyloid precursor protein catabolic process	BP	0.15	0.00216	0.0118	1.93	0.00766	Igf1/Aph1b/Rtn1/Slc2a13/Apoe/Bin1/Abcg1/Adam19/Psen1	9
GO:0045444	fat cell differentiation	BP	0.0909	0.00219	0.012	1.92	0.00777	Sfrp2/Igf1/Fermt2/Lama4/Runx1t1/Arl6/Vstm2a/Id4/Bbs7/Plcb1/Glis1/Sh2b2/Gdf10/Enpp1/Dysf/Htr2a/Lrp3/Arxes2/Steap4/Bbs1/Dact1/Lrrc8c/Bmp7/Cds1	24
GO:0010769	regulation of cell morphogenesis involved in differentiation	BP	0.115	0.00221	0.0121	1.92	0.00783	Mdk/Ptprd/Nrp1/Fermt2/Tbc1d24/Has2/Obsl1/Postn/Caprin2/Bhlhb9/Net1/Cux2/Enpp2/Numbl	14
GO:0034367	protein-containing complex remodeling	BP	0.207	0.00223	0.0122	1.91	0.00789	Apob/Pla2g10/Pltp/Apoe/Abca5/Abcg1	6
GO:1904861	excitatory synapse assembly	BP	0.207	0.00223	0.0122	1.91	0.00789	Ptprd/Nlgn1/Lrrc4b/Nptx1/Slitrk3/Nlgn2	6
GO:0048639	positive regulation of developmental growth	BP	0.0955	0.00224	0.0122	1.91	0.00792	Gli1/Sema5a/Igf1/Tbx2/Cpne5/Nrp1/Acacb/Sema7a/Fn1/Mef2c/Cxcl12/Hopx/Plcb1/Flt3/Apoe/Igf2/Slc23a2/Foxs1/Cacng7/Stat5b/Hey2	21
GO:0072089	stem cell proliferation	BP	0.131	0.00225	0.0123	1.91	0.00795	Sfrp2/Fermt2/Tert/Znrf3/Vegfc/Tbx3/Kitl/Ltbp3/Septin4/Abcb1a/Nes	11
GO:0007405	neuroblast proliferation	BP	0.139	0.00226	0.0123	1.91	0.00795	Acsl6/Hhip/Lef1/Lrrk2/Id4/Gli3/Eml1/Vegfc/Ptn/Numbl	10
GO:0055008	cardiac muscle tissue morphogenesis	BP	0.139	0.00226	0.0123	1.91	0.00795	Col11a1/Angpt1/Nog/Lrp2/Ccm2l/Ednra/Myl3/Heg1/Hey2/Eng	10
GO:0071868	cellular response to monoamine stimulus	BP	0.139	0.00226	0.0123	1.91	0.00795	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Palm/Atp2b4/Gnb5	10
GO:0071870	cellular response to catecholamine stimulus	BP	0.139	0.00226	0.0123	1.91	0.00795	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Palm/Atp2b4/Gnb5	10
GO:0031281	positive regulation of cyclase activity	BP	0.179	0.00232	0.0125	1.9	0.00812	Cacna1c/Vipr2/Nos3/Adcy3/Calca/Adcy4/Adcy7	7
GO:0045981	positive regulation of nucleotide metabolic process	BP	0.179	0.00232	0.0125	1.9	0.00812	Igf1/Nos3/Htr2a/Zbtb20/Psen1/Pid1/Myc	7
GO:0051180	vitamin transport	BP	0.179	0.00232	0.0125	1.9	0.00812	Stra6/Slc2a3/Abcg2/Lrp2/Slc23a2/Abcc5/Abcg3	7
GO:0051481	negative regulation of cytosolic calcium ion concentration	BP	0.179	0.00232	0.0125	1.9	0.00812	Kcnk3/Slc8a1/Calca/Pkd2/Gstm7/Atp1a2/Sri	7
GO:1900544	positive regulation of purine nucleotide metabolic process	BP	0.179	0.00232	0.0125	1.9	0.00812	Igf1/Nos3/Htr2a/Zbtb20/Psen1/Pid1/Myc	7
GO:0001890	placenta development	BP	0.101	0.0024	0.0129	1.89	0.00838	Ndp/Lef1/Itga4/Slc8a1/Il11ra1/Vash1/Syde1/Prdm1/Pcdh12/Cdkn1c/Igf2/Snai1/Pkd1/Pkd2/Ptn/Vash2/Bmp7/Hey2	18
GO:0010656	negative regulation of muscle cell apoptotic process	BP	0.148	0.00243	0.013	1.88	0.00845	Sfrp2/Gria4/Mdk/Igf1/Agtr1a/Arrb2/Cav1/Hey2/Hand2	9
GO:0060324	face development	BP	0.148	0.00243	0.013	1.88	0.00845	Stra6/Lef1/Itga4/Nog/Crispld1/Mmp2/Ednra/Twist2/Asph	9
GO:0099172	presynapse organization	BP	0.148	0.00243	0.013	1.88	0.00845	Gpc6/Ptprd/Nlgn1/Lrrc4b/Slitrk3/Nlgn3/Pcdh17/Lrp4/Nlgn2	9
GO:1902930	regulation of alcohol biosynthetic process	BP	0.16	0.00248	0.0133	1.88	0.00861	Apob/Pth1r/Dkk3/Apoe/Adcyap1r1/Abcg1/Abcg4/Plek	8
GO:0046530	photoreceptor cell differentiation	BP	0.129	0.00248	0.0133	1.88	0.00861	Ihh/Sdk2/Thy1/Prdm1/Rp1/Rorb/Ttc26/Arl3/Nphp1/Bbs1/Ptn	11
GO:0008542	visual learning	BP	0.137	0.00251	0.0134	1.87	0.00871	Cacna1c/Nog/B4galt2/Pde1b/Cacna1e/Kit/Nlgn3/Ddhd2/Atp1a2/Syngap1	10
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	BP	0.106	0.00255	0.0137	1.86	0.00885	Adra1a/Adgrl4/Adcy3/Cxcr3/Ptgfr/Adgrl1/Calca/Pth1r/Adcy4/Adcy7/Gpr161/Calcrl/Ptger3/Atp2b4/S1pr3/Ptger2	16
GO:0043491	protein kinase B signaling	BP	0.0962	0.00259	0.0138	1.86	0.00896	Sema5a/Angpt1/Kdr/Igf1/Hcls1/Fermt2/Inpp4b/Tek/Cxcl12/Lrp2/Nox4/Magi2/Igf2/Cavin3/Rcn3/Arrb2/Rasd2/Setx/Eng/Irs1	20
GO:0019693	ribose phosphate metabolic process	BP	0.0824	0.00261	0.0139	1.86	0.00901	Nme4/Acsl6/Igf1/Hmgcs2/Acacb/Lrrk2/Adcy3/Them5/Gucy1b1/Gucy1a1/Adcy4/Dhtkd1/Adcy7/Enpp1/Htr2a/Acot7/Zbtb20/Pde5a/Rab23/Acsl1/Impdh1/Dpyd/Psen1/Pid1/Pfkm/Cacnb4/Pygl/Myc/Papss2/Suclg2/Acot6	31
GO:0030004	cellular monovalent inorganic cation homeostasis	BP	0.117	0.00261	0.0139	1.86	0.00901	Slc1a3/Slc8a1/Lrrk2/Slc9a7/Dmxl2/Lacc1/Kcnma1/Slc9a5/Slc4a3/Aqp11/Atp1a2/Slc4a8/Rab20	13
GO:1902106	negative regulation of leukocyte differentiation	BP	0.117	0.00261	0.0139	1.86	0.00901	Ihh/Mdk/Cd44/Inpp4b/Lrrc17/Gli3/Calca/Flt3/Loxl3/Tnfrsf11b/Zbtb46/Tnfaip6/Myc	13
GO:0016042	lipid catabolic process	BP	0.0851	0.00262	0.0139	1.86	0.00903	Apob/Cyp1b1/Aspg/Pla2g10/Acacb/Plcb1/Bdh2/Apoe/Pla1a/Echs1/Acot7/Cyp46a1/Plcb2/Ddhd2/Gimap5/Abcd2/Gimap3/Smpd1/Lipe/Pld2/Enpp2/Pafah2/Plbd1/Twist1/Abhd3/Acap1/Echdc2/Irs1	28
GO:0009150	purine ribonucleotide metabolic process	BP	0.0841	0.00266	0.014	1.85	0.00909	Nme4/Acsl6/Igf1/Hmgcs2/Acacb/Lrrk2/Adcy3/Them5/Gucy1b1/Gucy1a1/Adcy4/Dhtkd1/Adcy7/Enpp1/Htr2a/Acot7/Zbtb20/Pde5a/Rab23/Acsl1/Impdh1/Psen1/Pid1/Pfkm/Cacnb4/Myc/Papss2/Suclg2/Acot6	29
GO:0002274	myeloid leukocyte activation	BP	0.0896	0.00267	0.014	1.85	0.00909	Pla2g10/Fn1/Lrrk2/Foxf1/Slc7a2/Dock2/Cd1d1/Kit/Cd226/Havcr2/Cd200/Dysf/Myo1f/Cd84/Fgr/Gimap5/Gimap3/Psen1/Lat/Clnk/Nr1h3/Pld2/Batf/Lcp2	24
GO:1905039	carboxylic acid transmembrane transport	BP	0.109	0.00268	0.014	1.85	0.00909	Slc1a3/Acsl6/Slc7a2/Slc36a4/Lrp2/Slc23a2/Slc38a1/Abcd2/Acsl1/Slc7a7/Psen1/Abcb1a/Abcc5/Lrrc8c/Myc	15
GO:0010838	positive regulation of keratinocyte proliferation	BP	0.308	0.00268	0.014	1.85	0.00909	Mdk/Has2/Stxbp4/Twist2	4
GO:0014052	regulation of gamma-aminobutyric acid secretion	BP	0.308	0.00268	0.014	1.85	0.00909	Grik1/Abat/Htr1b/Gabbr1	4
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	BP	0.308	0.00268	0.014	1.85	0.00909	Angpt1/Kdr/Tek/Grb10	4
GO:0033625	positive regulation of integrin activation	BP	0.308	0.00268	0.014	1.85	0.00909	Fermt2/Rasip1/Pcsk5/Plek	4
GO:0034374	low-density lipoprotein particle remodeling	BP	0.308	0.00268	0.014	1.85	0.00909	Apob/Pla2g10/Apoe/Abcg1	4
GO:0034375	high-density lipoprotein particle remodeling	BP	0.308	0.00268	0.014	1.85	0.00909	Pltp/Apoe/Abca5/Abcg1	4
GO:0034392	negative regulation of smooth muscle cell apoptotic process	BP	0.308	0.00268	0.014	1.85	0.00909	Gria4/Igf1/Agtr1a/Arrb2	4
GO:0086067	AV node cell to bundle of His cell communication	BP	0.308	0.00268	0.014	1.85	0.00909	Cacna1c/Scn4b/Ank2/Gjc1	4
GO:1901841	regulation of high voltage-gated calcium channel activity	BP	0.308	0.00268	0.014	1.85	0.00909	Cacna2d1/Dysf/Rrad/Sri	4
GO:1902950	regulation of dendritic spine maintenance	BP	0.308	0.00268	0.014	1.85	0.00909	Grin2b/Apoe/Fyn/Zmynd8	4
GO:0006688	glycosphingolipid biosynthetic process	BP	0.2	0.00268	0.014	1.85	0.00909	St8sia2/St8sia4/St3gal2/St6galnac4/St8sia6/St6galnac6	6
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	BP	0.2	0.00268	0.014	1.85	0.00909	Angpt1/Kdr/Tek/Emilin1/Vegfc/Grb10	6
GO:0060343	trabecula formation	BP	0.2	0.00268	0.014	1.85	0.00909	Thbs3/Mmp2/Tek/Adamts1/Enpp1/Hey2	6
GO:0071312	cellular response to alkaloid	BP	0.2	0.00268	0.014	1.85	0.00909	Slc1a3/Ryr1/Slc8a1/Htr1b/Selenon/Gstm7	6
GO:0001782	B cell homeostasis	BP	0.175	0.0027	0.0141	1.85	0.00914	Cd44/Mef2c/Sh2b2/Tnfsf13b/Dock10/Enpp1/Nckap1l	7
GO:0051349	positive regulation of lyase activity	BP	0.175	0.0027	0.0141	1.85	0.00914	Cacna1c/Vipr2/Nos3/Adcy3/Calca/Adcy4/Adcy7	7
GO:0060325	face morphogenesis	BP	0.175	0.0027	0.0141	1.85	0.00914	Stra6/Lef1/Nog/Crispld1/Mmp2/Twist2/Asph	7
GO:0010952	positive regulation of peptidase activity	BP	0.1	0.00271	0.0141	1.85	0.00915	Sfrp2/Aph1b/Bok/Wdr35/Grin2b/Ift57/Ppm1f/Hip1/Arrb1/Rcn3/Dlc1/Asph/Fyn/Nlrp1b/Ccn2/Cyfip2/F2r/Myc	18
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	BP	0.238	0.00272	0.0141	1.85	0.00915	Adra1a/P2rx2/Calca/Rps6ka2/Agtr1a	5
GO:0007190	activation of adenylate cyclase activity	BP	0.238	0.00272	0.0141	1.85	0.00915	Vipr2/Adcy3/Calca/Adcy4/Adcy7	5
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	BP	0.238	0.00272	0.0141	1.85	0.00915	Kdr/Nrp1/Jcad/Hdac9/Akt3	5
GO:0097107	postsynaptic density assembly	BP	0.238	0.00272	0.0141	1.85	0.00915	Ptprd/Lrrc4b/Nptx1/Slitrk3/Nlgn2	5
GO:0051261	protein depolymerization	BP	0.112	0.00278	0.0144	1.84	0.00933	Map2/Sema5a/Evl/Tmod2/Mical1/Rp1/Sh3bp1/Scin/Dysf/Asph/Ttbk2/Nes/Plekhh2/Plek	14
GO:0071867	response to monoamine	BP	0.135	0.00278	0.0144	1.84	0.00933	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Palm/Atp2b4/Gnb5	10
GO:0071869	response to catecholamine	BP	0.135	0.00278	0.0144	1.84	0.00933	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Palm/Atp2b4/Gnb5	10
GO:0008038	neuron recognition	BP	0.157	0.00282	0.0145	1.84	0.00943	Gap43/Prtg/Efnb3/Ptprz1/Sema5a/Nrp1/Ndn/Epha3	8
GO:0042088	T-helper 1 type immune response	BP	0.157	0.00282	0.0145	1.84	0.00943	Lef1/H2-Ab1/Il27ra/Cracr2a/Havcr2/Xcl1/Il12rb1/Spn	8
GO:0030177	positive regulation of Wnt signaling pathway	BP	0.108	0.00287	0.0148	1.83	0.0096	Sfrp2/Sema5a/Lef1/Zeb2/Nkd1/Tert/Gpc3/Lrrk2/Gprc5b/Peg12/Daam2/Caprin2/Adgra2/Cav1/Dact1	15
GO:1903825	organic acid transmembrane transport	BP	0.108	0.00287	0.0148	1.83	0.0096	Slc1a3/Acsl6/Slc7a2/Slc36a4/Lrp2/Slc23a2/Slc38a1/Abcd2/Acsl1/Slc7a7/Psen1/Abcb1a/Abcc5/Lrrc8c/Myc	15
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	BP	0.0952	0.00289	0.0149	1.83	0.00965	Hgf/Sfrp2/Igf1/Cd44/Bok/Wdr35/Mical1/Ift57/Wnt9a/Ppm1f/Hip1/Arrb1/Epha7/Dlc1/Arrb2/Nlrp1b/Ccn2/Mgmt/F2r/Myc	20
GO:0016311	dephosphorylation	BP	0.0836	0.0029	0.0149	1.83	0.00966	Ptprz1/Ptprd/Npnt/Ptpro/Mef2c/Ptp4a3/Inpp4b/Itga1/Ptpdc1/Ptprm/Cdh5/Plpp3/Lhpp/Ppm1f/Ppp1r16b/Bpnt1/Magi2/Ppm1e/Nckap1l/Cmya5/Dlc1/Plpp1/Ppp1r26/Smpd1/Pdgfrb/Vcan/Plek/Ptpn7/Plppr2	29
GO:0072175	epithelial tube formation	BP	0.102	0.00292	0.015	1.82	0.00971	Sfrp2/Wnt6/Nog/Zeb2/Ift57/Gdf7/Lrp2/Cecr2/Prickle1/Ipmk/Dlc1/Ptch1/Osr1/Rab23/Fzd2/Bmp7/Twist1	17
GO:0042267	natural killer cell mediated cytotoxicity	BP	0.126	0.00298	0.0153	1.81	0.00993	Pik3r6/Coro1a/Cd226/Havcr2/Igf2/Arrb2/Stat5b/Gimap5/Gzmb/Gimap3/Rab27a	11
GO:0010517	regulation of phospholipase activity	BP	0.143	0.00304	0.0156	1.81	0.0101	Adra1a/Itk/Arhgap6/Agtr1a/Sele/Adcyap1r1/Htr2a/Dlc1/Pdgfrb	9
GO:0030865	cortical cytoskeleton organization	BP	0.143	0.00304	0.0156	1.81	0.0101	Nlgn1/Epb41l3/Rhobtb3/Nckap1l/Cavin3/Akap11/Pdcd6ip/Fmnl3/Plek	9
GO:0009259	ribonucleotide metabolic process	BP	0.0824	0.00304	0.0156	1.81	0.0101	Nme4/Acsl6/Igf1/Hmgcs2/Acacb/Lrrk2/Adcy3/Them5/Gucy1b1/Gucy1a1/Adcy4/Dhtkd1/Adcy7/Enpp1/Htr2a/Acot7/Zbtb20/Pde5a/Rab23/Acsl1/Impdh1/Dpyd/Psen1/Pid1/Pfkm/Cacnb4/Myc/Papss2/Suclg2/Acot6	30
GO:0035148	tube formation	BP	0.0989	0.00306	0.0156	1.81	0.0101	Sfrp2/Wnt6/Nog/Zeb2/Ift57/Gdf7/Lrp2/Cecr2/Prickle1/Ipmk/Dlc1/Ptch1/Osr1/Rab23/Fzd2/Edar/Bmp7/Twist1	18
GO:1903707	negative regulation of hemopoiesis	BP	0.115	0.00306	0.0156	1.81	0.0101	Ihh/Mdk/Cd44/Inpp4b/Lrrc17/Gli3/Calca/Flt3/Loxl3/Tnfrsf11b/Zbtb46/Tnfaip6/Myc	13
GO:0006885	regulation of pH	BP	0.12	0.00307	0.0157	1.81	0.0101	Car4/Lrrk2/Ednrb/Slc9a7/Dmxl2/Agtr1a/Lacc1/Slc9a5/Slc4a3/Aqp11/Slc4a8/Rab20	12
GO:0048645	animal organ formation	BP	0.133	0.00307	0.0157	1.8	0.0102	Ar/Wnt11/Hoxd11/Nog/Hoxa11/Mef2c/Gli3/Lrp2/Bmp7/Hand2	10
GO:0051149	positive regulation of muscle cell differentiation	BP	0.133	0.00307	0.0157	1.8	0.0102	Igf1/Mef2c/Hopx/Tshz3/Kit/Cth/Arrb2/Efemp2/Camk1/Eng	10
GO:0062013	positive regulation of small molecule metabolic process	BP	0.101	0.0031	0.0158	1.8	0.0102	Igf1/Nos3/Pth1r/Igf2/Adcyap1r1/Htr2a/Zbtb20/Abcg1/Abcd2/Psen1/Nr1h3/Pid1/Rdh1/Abcg4/Myc/Twist1/Irs1	17
GO:0031348	negative regulation of defense response	BP	0.0913	0.00311	0.0158	1.8	0.0103	Hgf/Acod1/Mdk/Pla2g10/Igf1/Cd44/Ets1/Foxf1/Fndc4/Cdh5/Apoe/Havcr2/Cd200/Igf2/Tnfaip6/Mapkbp1/Arrb2/Calcrl/Cd96/Nr1h3/Spn/Wfdc1	22
GO:0003230	cardiac atrium development	BP	0.171	0.00312	0.0159	1.8	0.0103	Wnt11/Nog/Ank2/Ccm2l/Heg1/Hey2/Eng	7
GO:0071604	transforming growth factor beta production	BP	0.171	0.00312	0.0159	1.8	0.0103	Wnt11/Fn1/Tsku/Cd200/Ltbp3/Nrros/Lum	7
GO:0043254	regulation of protein-containing complex assembly	BP	0.0793	0.00316	0.016	1.79	0.0104	Kank4/Map2/Evl/Hcls1/Stx1b/Fermt2/Tmod2/Pfn2/Icam1/Jam3/Cdh5/Msn/Coro1a/Esam/Tubb4a/Apoe/Rasip1/Prrt2/Daam2/Pecam1/Scin/Bin1/Nckap1l/Nin/Slain1/Pcsk5/Tal1/Arhgap28/Cdc42ep5/Cav1/Cyfip2/Dact1/Tppp/Plek	34
GO:0016050	vesicle organization	BP	0.0871	0.00318	0.016	1.79	0.0104	Zeb2/Syt13/Sec16b/Stx1b/Ap1m1/Serpine2/Rab34/Srpx/Coro1a/Cadps/Syt7/Prrt2/Dysf/Abcg1/Fhip1b/Aqp11/Dlg4/Ccdc136/Arfgap3/Stx2/Rab27a/Nkd2/Golph3l/Pdcd6ip/Rab20	25
GO:0050798	activated T cell proliferation	BP	0.154	0.00319	0.016	1.79	0.0104	Igf1/Itgal/Il27ra/Igf2/Satb1/Stat5b/Fyn/Il12rb1	8
GO:0090279	regulation of calcium ion import	BP	0.154	0.00319	0.016	1.79	0.0104	Spink1/Stc1/Cxcl12/Agtr1a/Dysf/Pkd2/Fyn/Pdgfrb	8
GO:0002313	mature B cell differentiation involved in immune response	BP	0.194	0.00319	0.016	1.79	0.0104	Itm2a/Lfng/Dock10/Enpp1/Irf8/Mfng	6
GO:0021952	central nervous system projection neuron axonogenesis	BP	0.194	0.00319	0.016	1.79	0.0104	Dcc/Zeb2/Tsku/Cdh11/Nin/Draxin	6
GO:0032967	positive regulation of collagen biosynthetic process	BP	0.194	0.00319	0.016	1.79	0.0104	Ihh/Ddr2/Arrb2/Ccn2/Pdgfrb/F2r	6
GO:0045762	positive regulation of adenylate cyclase activity	BP	0.194	0.00319	0.016	1.79	0.0104	Cacna1c/Vipr2/Adcy3/Calca/Adcy4/Adcy7	6
GO:2000648	positive regulation of stem cell proliferation	BP	0.194	0.00319	0.016	1.79	0.0104	Fermt2/Tert/Vegfc/Tbx3/Kitl/Ltbp3	6
GO:0071674	mononuclear cell migration	BP	0.0984	0.00324	0.0163	1.79	0.0106	Mdk/Itga4/Cyp7b1/Ptpro/Itgb7/Icam1/Cxcr3/Cxcl12/Plcb1/Calca/Msn/Itgal/Il27ra/Pecam1/Cd200/Xcl1/Spn/Jam2	18
GO:0051937	catecholamine transport	BP	0.125	0.00326	0.0164	1.79	0.0106	Slc6a2/Syt13/Abat/Myo5a/Cxcl12/Htr1b/Cadps/Syt7/Htr2a/Ptger3/Gabbr1	11
GO:0120192	tight junction assembly	BP	0.125	0.00326	0.0164	1.79	0.0106	Wnt11/Mpdz/Cldn8/Cdh5/Esam/Pecam1/Snai1/Nphp1/Cldn5/Pdcd6ip/Cldn1	11
GO:0051224	negative regulation of protein transport	BP	0.106	0.0033	0.0165	1.78	0.0107	Angpt1/Pkdcc/Drd4/Lrrk2/Pkia/Ppm1f/Apoe/Cd200/Neo1/Frmd4a/Rab23/Ptger3/Nr1h3/F2r/Irs1	15
GO:0019216	regulation of lipid metabolic process	BP	0.0812	0.00331	0.0166	1.78	0.0107	Apob/Epha8/Igf1/Acacb/Tek/Kit/Dkk3/Agtr1a/Apoe/Kcnma1/Igf2/Snai1/Htr2a/Lpcat1/Zbtb20/Abcg1/Stat5b/Fgr/Angptl4/Gimap5/Abcd2/Gimap3/Pdgfrb/Cav1/Nr1h3/Rdh1/Bcl11b/Abcg4/Twist1/Asxl3/Irs1	31
GO:0043576	regulation of respiratory gaseous exchange	BP	0.227	0.00338	0.0169	1.77	0.0109	Nlgn1/Tshz3/Nlgn3/Atp1a2/Nlgn2	5
GO:0046325	negative regulation of glucose import	BP	0.227	0.00338	0.0169	1.77	0.0109	Sh2b2/Enpp1/Pid1/Grb10/Myc	5
GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	BP	0.227	0.00338	0.0169	1.77	0.0109	Rims3/Stx1b/Cadps/Syt7/Cacna1a	5
GO:0071398	cellular response to fatty acid	BP	0.227	0.00338	0.0169	1.77	0.0109	Id3/Plcb1/Nfatc4/Pid1/Irs1	5
GO:1900746	regulation of vascular endothelial growth factor signaling pathway	BP	0.227	0.00338	0.0169	1.77	0.0109	Ptp4a3/Jcad/Tcf4/Adgra2/Sema6a	5
GO:1902115	regulation of organelle assembly	BP	0.0939	0.0034	0.0169	1.77	0.011	Gap43/Fez1/Ptprd/Ccdc88a/Adamts16/Lrrk2/Lrrc4b/Nptx1/Msn/Kctd17/Rp1/Nptxr/Crocc/Ttbk2/Dzip1/Dync2li1/Cep97/Arhgef9/Atmin/Pdcd6ip	20
GO:0006644	phospholipid metabolic process	BP	0.0817	0.00343	0.0171	1.77	0.0111	Acsl6/Aspg/Pla2g10/Hmgcs2/Efr3b/Pip5k1b/Inpp4b/Plcb1/Them5/Plpp3/Ttc7b/Dgkb/Bpnt1/Htr2a/Lpcat1/Plcb2/Abca8b/Plpp1/Abhd8/Smpd1/Pdgfrb/Nr1h3/Pld2/Enpp2/Plbd1/Plek/Mboat2/Cds1/Abhd3/Plppr2	30
GO:0030595	leukocyte chemotaxis	BP	0.0921	0.00343	0.0171	1.77	0.0111	Cxcl15/Mdk/Cyp7b1/Ptpro/Ednrb/Jam3/Cxcr3/Cxcl12/Edn3/Itga1/Calca/Coro1a/Kit/Vegfc/Ednra/Dysf/Nckap1l/Xcl1/Tnfaip6/Mpp1/Ptn	21
GO:0046942	carboxylic acid transport	BP	0.0865	0.00348	0.0173	1.76	0.0112	Slc1a3/Grik1/Pla2g10/Slc13a5/Abat/Drd4/Slc7a2/Grin2b/Abcg2/Slc36a4/Lrp2/Htr1b/Slc6a15/Slc23a2/Bdkrb2/Sfxn5/Slc38a1/Nfkbie/Psen1/Abcc5/Gabbr1/Cacna1a/Lrrc8c/Cacnb4/Myc	25
GO:0007565	female pregnancy	BP	0.1	0.0035	0.0174	1.76	0.0113	Acod1/Ar/Cbs/Il11ra1/Mmp2/Abcg2/Calca/Syde1/Prdm1/Maged2/Havcr2/Klf9/Pcsk5/Stat5b/Stx2/Ptn/Itgb4	17
GO:0010950	positive regulation of endopeptidase activity	BP	0.1	0.0035	0.0174	1.76	0.0113	Sfrp2/Aph1b/Bok/Wdr35/Grin2b/Ift57/Ppm1f/Hip1/Arrb1/Dlc1/Asph/Fyn/Nlrp1b/Ccn2/Cyfip2/F2r/Myc	17
GO:0002367	cytokine production involved in immune response	BP	0.113	0.00356	0.0176	1.76	0.0114	Angpt1/Sema7a/Tek/Gprc5b/Tril/Kit/Cd226/Lacc1/Xcl1/Gimap5/Gimap3/Clnk/Cd96	13
GO:0045638	negative regulation of myeloid cell differentiation	BP	0.124	0.00357	0.0176	1.76	0.0114	Inpp4b/Lrrc17/Calca/Tnfrsf11b/Gpr171/Zbtb46/Tnfaip6/Hoxa9/Twist2/Stat5b/Myc	11
GO:0010092	specification of animal organ identity	BP	0.167	0.0036	0.0176	1.76	0.0114	Ar/Wnt11/Hoxd11/Hoxa11/Mef2c/Gli3/Lrp2	7
GO:0090175	regulation of establishment of planar polarity	BP	0.167	0.0036	0.0176	1.76	0.0114	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Fzd2/Dact1	7
GO:0099174	regulation of presynapse organization	BP	0.167	0.0036	0.0176	1.76	0.0114	Gpc6/Ptprd/Nlgn1/Lrrc4b/Slitrk3/Nlgn3/Nlgn2	7
GO:0030850	prostate gland development	BP	0.151	0.0036	0.0176	1.76	0.0114	Ar/Cyp7b1/Nog/Igf1/Cd44/Mmp2/Id4/Bmp7	8
GO:0003207	cardiac chamber formation	BP	0.286	0.00361	0.0176	1.76	0.0114	Tbx2/Mef2c/Ednra/Hand2	4
GO:0009312	oligosaccharide biosynthetic process	BP	0.286	0.00361	0.0176	1.76	0.0114	B3galnt1/St3gal2/St6galnac6/St3gal4	4
GO:0030432	peristalsis	BP	0.286	0.00361	0.0176	1.76	0.0114	Tbx2/P2rx2/Tshz3/Tbx3	4
GO:0032253	dense core granule localization	BP	0.286	0.00361	0.0176	1.76	0.0114	Map2/Ppfia2/Kif1a/Kif5a	4
GO:0032341	aldosterone metabolic process	BP	0.286	0.00361	0.0176	1.76	0.0114	Ednrb/Dkk3/Kcnma1/Cacna1h	4
GO:0045060	negative thymic T cell selection	BP	0.286	0.00361	0.0176	1.76	0.0114	Gli3/Dock2/Zap70/Spn	4
GO:0046058	cAMP metabolic process	BP	0.286	0.00361	0.0176	1.76	0.0114	Adcy3/Adcy4/Adcy7/Cacnb4	4
GO:0061309	cardiac neural crest cell development involved in outflow tract morphogenesis	BP	0.286	0.00361	0.0176	1.76	0.0114	Ednra/Bmp7/Hand2/Twist1	4
GO:0098840	protein transport along microtubule	BP	0.286	0.00361	0.0176	1.76	0.0114	Myo5a/Kif1a/Dlg2/Kif5a	4
GO:0099118	microtubule-based protein transport	BP	0.286	0.00361	0.0176	1.76	0.0114	Myo5a/Kif1a/Dlg2/Kif5a	4
GO:1901201	regulation of extracellular matrix assembly	BP	0.286	0.00361	0.0176	1.76	0.0114	Phldb2/Has2/Emilin1/Tie1	4
GO:1901950	dense core granule transport	BP	0.286	0.00361	0.0176	1.76	0.0114	Map2/Ppfia2/Kif1a/Kif5a	4
GO:1903238	positive regulation of leukocyte tethering or rolling	BP	0.286	0.00361	0.0176	1.76	0.0114	Itga4/Chst2/Sele/St3gal4	4
GO:1903441	protein localization to ciliary membrane	BP	0.286	0.00361	0.0176	1.76	0.0114	Tub/Arl6/Arl3/Rabep1	4
GO:1905063	regulation of vascular associated smooth muscle cell differentiation	BP	0.286	0.00361	0.0176	1.76	0.0114	Kit/Cth/Efemp2/Eng	4
GO:0001708	cell fate specification	BP	0.118	0.00361	0.0176	1.76	0.0114	Ihh/Sfrp2/Ar/Wnt11/Hoxd10/Ptch2/Tbx2/Hoxa11/Gli3/Tbx3/Ptch1/Psen1	12
GO:0045834	positive regulation of lipid metabolic process	BP	0.0973	0.00364	0.0177	1.75	0.0115	Epha8/Igf1/Tek/Agtr1a/Apoe/Igf2/Htr2a/Zbtb20/Abcg1/Fgr/Angptl4/Abcd2/Pdgfrb/Nr1h3/Rdh1/Abcg4/Twist1/Irs1	18
GO:0051047	positive regulation of secretion	BP	0.0791	0.00368	0.0179	1.75	0.0116	Grik1/Pla2g10/Igf1/Nlgn1/Abat/Stx1b/Ednrb/Ano1/Grin2b/Cxcl12/Edn3/Rab34/Cadps/Vegfc/Cd38/Syt7/Arrb1/Abcg1/Frmd4a/Ncs1/Cacna1h/Fgr/Apln/Slc4a8/Rab27a/Sri/Gabbr1/Pld2/Pfkm/Golph3l/Pdcd6ip/Nlgn2/Irs1	33
GO:0034219	carbohydrate transmembrane transport	BP	0.109	0.0037	0.018	1.75	0.0116	Igf1/Slc2a3/Tert/Gpc3/Stxbp4/Sh2b2/Enpp1/Ednra/Slc23a2/Abcb1a/Pid1/Grb10/Myc/Irs1	14
GO:0042471	ear morphogenesis	BP	0.105	0.00377	0.0182	1.74	0.0118	Col11a1/Nog/Tbx2/Lrig3/Osr2/Tshz1/Zeb1/Enpp1/Tbx3/Ednra/Osr1/Fzd2/Kcnq4/Itga8/Myc	15
GO:0019751	polyol metabolic process	BP	0.112	0.00384	0.0186	1.73	0.012	Inpp4b/Sptlc3/Plcb1/Pth1r/Plpp3/Bpnt1/Dysf/Degs2/Adcyap1r1/Ipmk/Sord/Plpp1/Plek	13
GO:0051952	regulation of amine transport	BP	0.112	0.00384	0.0186	1.73	0.012	Grik1/Syt13/Abat/Myo5a/Grin2b/Cxcl12/Htr1b/Syt7/Htr2a/Ptger3/Psen1/Gabbr1/Cacna1a	13
GO:0008593	regulation of Notch signaling pathway	BP	0.122	0.00389	0.0188	1.73	0.0122	Postn/Lfng/Jag2/Kit/Arrb1/Tspan5/Egfl7/Mfng/Bend6/Bmp7/Hey2	11
GO:0010827	regulation of glucose transmembrane transport	BP	0.122	0.00389	0.0188	1.73	0.0122	Igf1/Tert/Gpc3/Stxbp4/Sh2b2/Enpp1/Ednra/Pid1/Grb10/Myc/Irs1	11
GO:0033138	positive regulation of peptidyl-serine phosphorylation	BP	0.108	0.00397	0.0191	1.72	0.0124	Sfrp2/Angpt1/Hcls1/Cd44/Pfn2/Prkd1/Tek/Caprin2/Arrb1/Arrb2/Atp2b4/Cav1/Sh2d3c/Camk1	14
GO:0043406	positive regulation of MAP kinase activity	BP	0.108	0.00397	0.0191	1.72	0.0124	Zeb2/Drd4/Lrrk2/Pik3r6/Edn3/Kit/Nox4/Kitl/Htr2a/Pde5a/Psen1/Pdgfrb/Map4k2/Fgd2	14
GO:1990266	neutrophil migration	BP	0.108	0.00397	0.0191	1.72	0.0124	Cxcl15/Mdk/Jam3/Edn3/Itga1/Ednra/Pecam1/Dysf/Nckap1l/Xcl1/Tnfaip6/Irak4/Ptger3/Mpp1	14
GO:0031103	axon regeneration	BP	0.148	0.00405	0.0195	1.71	0.0126	Gap43/Mmp2/Enpp1/Rtn4rl1/Neo1/Xylt1/Ptn/Nrep	8
GO:0032892	positive regulation of organic acid transport	BP	0.148	0.00405	0.0195	1.71	0.0126	Acsl6/Grik1/Pla2g10/Abat/Grin2b/Acsl1/Psen1/Gabbr1	8
GO:0034331	cell junction maintenance	BP	0.163	0.00412	0.0197	1.7	0.0128	Epb41l3/Fermt2/Shank2/Erc2/Syngap1/Cldn1/F2r	7
GO:0042220	response to cocaine	BP	0.163	0.00412	0.0197	1.7	0.0128	Slc1a3/Abat/Drd4/Htr1b/Htr2a/Dlg4/Smpd1	7
GO:0048873	homeostasis of number of cells within a tissue	BP	0.163	0.00412	0.0197	1.7	0.0128	Tex15/Col14a1/Nos3/Flt3/Coro1a/Akt3/F2r	7
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	BP	0.217	0.00415	0.0199	1.7	0.0129	Sema5a/Ppp1r16b/Aplnr/Jcad/Agtr1a	5
GO:0098656	anion transmembrane transport	BP	0.0941	0.00416	0.0199	1.7	0.0129	Slc1a3/Slc13a5/Tcaf1/Slc12a8/Ano1/Slc7a2/Ano2/Lrp2/Glrb/Gabra4/Slc23a2/Slc12a4/Slc4a8/Psen1/Abcb1a/Abcc5/Lrrc8c/Ank/Myc	19
GO:0048286	lung alveolus development	BP	0.136	0.00418	0.02	1.7	0.013	Stra6/Kdr/Igf1/Pkdcc/Foxf1/Hopx/Tcf21/Ltbp3/Selenon	9
GO:0090288	negative regulation of cellular response to growth factor stimulus	BP	0.115	0.00424	0.0202	1.69	0.0131	Sfrp2/Nog/Lrp2/Emilin1/Hipk2/Tnfaip6/Atp2b4/Apln/Adgra2/Sema6a/Cav1/Tmprss6	12
GO:0010639	negative regulation of organelle organization	BP	0.0804	0.00433	0.0206	1.69	0.0134	Kank4/Hgf/Map2/Fez1/Igf1/Evl/Phldb2/Tmod2/Bok/Lrrk2/Pfn2/Klhl22/Rps6ka2/Cdh5/Coro1a/Rp1/Arhgap6/Tubb4a/Prrt2/Pecam1/Tmeff2/Scin/Dysf/Dlc1/Arrb2/Arhgap28/Ttbk2/Cep97/Plekhh2/Bmp7	30
GO:0051259	protein complex oligomerization	BP	0.0887	0.00438	0.0209	1.68	0.0135	Kcnb2/Kcna6/Kcnd2/Evl/Kcnd3/Acacb/Bok/Grin2b/Ikzf4/Cth/Kcnc4/Pkd1/Mpp2/Pkd2/Nlrp1b/Aqp11/Kcng4/Steap4/Lrrc8c/Pdcd6ip/Cldn1/Kctd12	22
GO:0050999	regulation of nitric-oxide synthase activity	BP	0.182	0.00442	0.021	1.68	0.0136	Npr3/Tert/Apoe/Atp2b4/Cav1/Eng	6
GO:0008585	female gonad development	BP	0.11	0.00445	0.0211	1.68	0.0137	Angpt1/Kdr/Nos3/Fst/Mmp2/Adamts1/Lfng/Kit/Kitl/Arrb1/Tnfaip6/Arrb2/Stat5b	13
GO:0051897	positive regulation of protein kinase B signaling	BP	0.11	0.00445	0.0211	1.68	0.0137	Sema5a/Angpt1/Igf1/Hcls1/Fermt2/Tek/Cxcl12/Lrp2/Nox4/Igf2/Arrb2/Rasd2/Eng	13
GO:0071692	protein localization to extracellular region	BP	0.0788	0.00445	0.0211	1.68	0.0137	Cacna1c/Igf1/Abat/Drd4/Ednrb/Myo5a/Ano1/Cacna1e/Stxbp4/Rab34/Vegfc/Cd38/Agtr1a/Apoe/Syt7/Cd200/Arrb1/Rcn3/Neo1/Nrros/P3h1/Abcg1/Frmd4a/Ptger3/Sri/Nr1h3/Pfkm/Golph3l/F2r/Nlgn2/Plek/Irs1	32
GO:0051057	positive regulation of small GTPase mediated signal transduction	BP	0.127	0.0045	0.0213	1.67	0.0138	Igf1/Lpar4/Dock2/Adcyap1r1/Kitl/Arrb1/Net1/Mapre2/Pdgfrb/F2r	10
GO:0052548	regulation of endopeptidase activity	BP	0.081	0.0045	0.0213	1.67	0.0138	Hgf/Sfrp2/Spink1/Igf1/Aph1b/Cd44/Bok/Wdr35/Grin2b/Mical1/Serpine2/Ift57/Serpini1/Wnt9a/Ppm1f/Hip1/Bin1/Arrb1/Epha7/Dlc1/Arrb2/Asph/Fyn/Nlrp1b/Ccn2/Mgmt/Cyfip2/F2r/Myc	29
GO:0010038	response to metal ion	BP	0.0847	0.00453	0.0214	1.67	0.0139	Slc13a5/Nlgn1/Syt13/Abat/Cpne5/Fn1/Lrrk2/Mef2c/Nptx1/Rasgrp2/Adcy7/Dlg2/Enpp1/Syt7/Kcnma1/Nfatc4/Kcnip3/Asph/Pkd2/Slc25a23/Sord/Dlg4/Smpd1/Cav1/Kcnh1	25
GO:0046394	carboxylic acid biosynthetic process	BP	0.0847	0.00453	0.0214	1.67	0.0139	Slc1a3/Gulo/Pla2g10/Fads2/Cyp7b1/Fads1/Abat/Acacb/Cbs/Myo5a/Elovl4/Gamt/Cth/Phgdh/Fads3/Acot7/Atp2b4/Abcd2/Gstm7/Asl/Nr1h3/Hacd1/Rdh1/Olah/Abhd3	25
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	BP	0.145	0.00455	0.0214	1.67	0.0139	Adra1a/Nos3/Ednrb/Enpep/Edn3/Rps6ka2/Agtr1a/F2r	8
GO:0034113	heterotypic cell-cell adhesion	BP	0.145	0.00455	0.0214	1.67	0.0139	Itga4/Cd44/Itgb7/Jam3/Thy1/Cd200/Itga7/Bmp7	8
GO:0046580	negative regulation of Ras protein signal transduction	BP	0.145	0.00455	0.0214	1.67	0.0139	Adra1a/Rasa3/Rasip1/Arap3/Heg1/Dlc1/Syngap1/Rasal3	8
GO:0048546	digestive tract morphogenesis	BP	0.145	0.00455	0.0214	1.67	0.0139	Stra6/Ihh/Sfrp2/Foxf1/Tcf21/Gli3/Stx2/Dact1	8
GO:1902476	chloride transmembrane transport	BP	0.145	0.00455	0.0214	1.67	0.0139	Slc1a3/Slc12a8/Ano1/Ano2/Glrb/Gabra4/Slc12a4/Slc4a8	8
GO:0043244	regulation of protein-containing complex disassembly	BP	0.106	0.00456	0.0214	1.67	0.0139	Map2/Sema5a/Evl/Tmod2/Rp1/Sh3bp1/Scin/Dysf/Asph/Ttbk2/Nes/Plekhh2/Setx/Plek	14
GO:0097581	lamellipodium organization	BP	0.12	0.00461	0.0217	1.66	0.014	Ccdc88a/Ptpro/Cd44/Wasf3/Abi3/Cdh13/Abi2/Kit/Parvb/Plekho1/Enpp2	11
GO:0001707	mesoderm formation	BP	0.134	0.00463	0.0217	1.66	0.0141	Sfrp2/Lef1/Wnt11/Nog/Hoxa11/Foxf1/Snai1/Tal1/Bmp7	9
GO:0030193	regulation of blood coagulation	BP	0.134	0.00463	0.0217	1.66	0.0141	Tfpi/Abat/Serpine2/Apoe/Pros1/Ptger3/St3gal4/Cav1/F2r	9
GO:0090398	cellular senescence	BP	0.134	0.00463	0.0217	1.66	0.0141	Tbx2/Tert/Abi3/Vash1/Tbx3/Smc5/Akt3/Cav1/Twist1	9
GO:0046640	regulation of alpha-beta T cell proliferation	BP	0.159	0.0047	0.022	1.66	0.0142	Cd44/Mapk8ip1/Btla/Xcl1/Zap70/Il12rb1/Rasal3	7
GO:0097028	dendritic cell differentiation	BP	0.159	0.0047	0.022	1.66	0.0142	Flt3/Irf8/Zbtb46/Gimap5/Gimap3/Psen1/Batf	7
GO:0016053	organic acid biosynthetic process	BP	0.0845	0.00473	0.022	1.66	0.0142	Slc1a3/Gulo/Pla2g10/Fads2/Cyp7b1/Fads1/Abat/Acacb/Cbs/Myo5a/Elovl4/Gamt/Cth/Phgdh/Fads3/Acot7/Atp2b4/Abcd2/Gstm7/Asl/Nr1h3/Hacd1/Rdh1/Olah/Abhd3	25
GO:0002396	MHC protein complex assembly	BP	0.267	0.00474	0.022	1.66	0.0142	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0002501	peptide antigen assembly with MHC protein complex	BP	0.267	0.00474	0.022	1.66	0.0142	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0003188	heart valve formation	BP	0.267	0.00474	0.022	1.66	0.0142	Erg/Dchs1/Hey2/Twist1	4
GO:0035721	intraciliary retrograde transport	BP	0.267	0.00474	0.022	1.66	0.0142	Wdr35/Dync2h1/Dync2li1/Bbs1	4
GO:0042693	muscle cell fate commitment	BP	0.267	0.00474	0.022	1.66	0.0142	AW551984/Tbx2/Mef2c/Tbx3	4
GO:0043383	negative T cell selection	BP	0.267	0.00474	0.022	1.66	0.0142	Gli3/Dock2/Zap70/Spn	4
GO:0072074	kidney mesenchyme development	BP	0.267	0.00474	0.022	1.66	0.0142	Tcf21/Osr1/Bmp7/Myc	4
GO:0099550	trans-synaptic signaling, modulating synaptic transmission	BP	0.267	0.00474	0.022	1.66	0.0142	Efnb3/Gucy1b1/Gucy1a1/F2r	4
GO:1901386	negative regulation of voltage-gated calcium channel activity	BP	0.267	0.00474	0.022	1.66	0.0142	Drd4/Dysf/Rrad/Gnb5	4
GO:0014020	primary neural tube formation	BP	0.109	0.00478	0.0221	1.65	0.0143	Sfrp2/Nog/Zeb2/Ift57/Lrp2/Cecr2/Prickle1/Dlc1/Ptch1/Rab23/Fzd2/Bmp7/Twist1	13
GO:0048709	oligodendrocyte differentiation	BP	0.109	0.00478	0.0221	1.65	0.0143	Ptprz1/Mdk/Wasf3/Id4/Gli3/Slc8a3/Nlgn3/Enpp1/Daam2/Ptn/Tppp/Enpp2/Zfp365	13
GO:0010469	regulation of signaling receptor activity	BP	0.102	0.00488	0.0226	1.65	0.0146	Begain/Nog/Nlgn1/Areg/Slc24a4/Mef2c/Nptx1/Cnrip1/Nlgn3/Nptxr/Prrt1/Cacng7/Dlg4/Psen1/Nlgn2	15
GO:0032103	positive regulation of response to external stimulus	BP	0.0764	0.00493	0.0228	1.64	0.0148	Sema5a/Acod1/Mdk/Kdr/Nrp1/Ets1/Fn1/Lrrk2/Mmp2/Prkd1/Cxcr3/Cdh13/Cxcl12/Gprc5b/Edn3/Rab34/Ppm1f/Cd226/Emilin1/Vegfc/Havcr2/Ednra/Dysf/Nckap1l/Xcl1/Masp1/Stat5b/Pde5a/Nlrp1b/Ptger3/Gimap5/Gimap3/Pdgfrb/Ptn/Clnk	35
GO:0009953	dorsal/ventral pattern formation	BP	0.113	0.00494	0.0228	1.64	0.0148	Gli1/Hhip/Hoxd11/Nog/Hoxa11/Gli3/Gpr161/Dync2h1/Ptch1/Rab23/Psen1/Lrp4	12
GO:0015844	monoamine transport	BP	0.113	0.00494	0.0228	1.64	0.0148	Maob/Slc6a2/Syt13/Abat/Myo5a/Cxcl12/Htr1b/Cadps/Syt7/Htr2a/Ptger3/Gabbr1	12
GO:0006898	receptor-mediated endocytosis	BP	0.0865	0.00496	0.0229	1.64	0.0148	Angpt1/Itga4/Clec9a/Drd4/Calca/Lrp2/Htr1b/Ldlrad3/Nlgn3/Apoe/Magi2/Sele/Hip1/Arrb1/Cacng7/Arrb2/Calcrl/Dlg4/Ptger3/Apln/Cav1/Pld2/Ankrd13a	23
GO:0051896	regulation of protein kinase B signaling	BP	0.0966	0.00498	0.0229	1.64	0.0149	Sema5a/Angpt1/Igf1/Hcls1/Fermt2/Inpp4b/Tek/Cxcl12/Lrp2/Nox4/Magi2/Igf2/Cavin3/Rcn3/Arrb2/Rasd2/Eng	17
GO:0044272	sulfur compound biosynthetic process	BP	0.118	0.00501	0.023	1.64	0.0149	Acsl6/Angpt1/Acacb/Cbs/Cth/Chst1/Dse/Acsl1/Xylt1/Ggt7/Papss2	11
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	BP	0.118	0.00501	0.023	1.64	0.0149	Gpc6/Stx1b/Drd4/Nptx1/Dlg2/Nptxr/Magi2/Nsg1/Cacng7/Cpt1c/Dlg4	11
GO:0003181	atrioventricular valve morphogenesis	BP	0.208	0.00504	0.0231	1.64	0.015	Heyl/Dchs1/Hey2/Slit3/Twist1	5
GO:0009190	cyclic nucleotide biosynthetic process	BP	0.208	0.00504	0.0231	1.64	0.015	Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7	5
GO:0030903	notochord development	BP	0.208	0.00504	0.0231	1.64	0.015	Gli1/Wnt11/Nog/Id3/Col13a1	5
GO:0036303	lymph vessel morphogenesis	BP	0.208	0.00504	0.0231	1.64	0.015	Vash1/Vegfc/Tie1/Pkd1/Svep1	5
GO:0052652	cyclic purine nucleotide metabolic process	BP	0.208	0.00504	0.0231	1.64	0.015	Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7	5
GO:0050433	regulation of catecholamine secretion	BP	0.132	0.00511	0.0234	1.63	0.0152	Syt13/Abat/Myo5a/Cxcl12/Htr1b/Syt7/Htr2a/Ptger3/Gabbr1	9
GO:0007498	mesoderm development	BP	0.108	0.00513	0.0234	1.63	0.0152	Sfrp2/Lef1/Wnt11/Nog/Hoxa11/Foxf1/Tbx3/Snai1/Tal1/Osr1/Pus7/Ets2/Bmp7	13
GO:0002092	positive regulation of receptor internalization	BP	0.176	0.00516	0.0235	1.63	0.0152	Angpt1/Magi2/Sele/Arrb1/Arrb2/Apln	6
GO:0010714	positive regulation of collagen metabolic process	BP	0.176	0.00516	0.0235	1.63	0.0152	Ihh/Ddr2/Arrb2/Ccn2/Pdgfrb/F2r	6
GO:0051497	negative regulation of stress fiber assembly	BP	0.176	0.00516	0.0235	1.63	0.0152	Kank4/Phldb2/Arhgap6/Tmeff2/Dlc1/Arhgap28	6
GO:0035303	regulation of dephosphorylation	BP	0.104	0.00521	0.0237	1.63	0.0154	Npnt/Mef2c/Itga1/Cdh5/Ppp1r16b/Magi2/Nckap1l/Cmya5/Dlc1/Ppp1r26/Smpd1/Pdgfrb/Vcan/Plek	14
GO:0071214	cellular response to abiotic stimulus	BP	0.0818	0.00524	0.0238	1.62	0.0154	Sfrp2/Wnt11/Nos3/Ccnd2/Mmp2/Slc24a4/Eif2ak4/Mme/Scn2a/Rp1/Cnn2/Ednra/Dysf/Bdkrb2/Nfatc4/Pkd2/Net1/Slc25a23/Habp4/Palm/Gnb5/Atp1a2/Smpd1/Piezo2/Cav1/Lrrc8c/Sipa1	27
GO:0104004	cellular response to environmental stimulus	BP	0.0818	0.00524	0.0238	1.62	0.0154	Sfrp2/Wnt11/Nos3/Ccnd2/Mmp2/Slc24a4/Eif2ak4/Mme/Scn2a/Rp1/Cnn2/Ednra/Dysf/Bdkrb2/Nfatc4/Pkd2/Net1/Slc25a23/Habp4/Palm/Gnb5/Atp1a2/Smpd1/Piezo2/Cav1/Lrrc8c/Sipa1	27
GO:0048661	positive regulation of smooth muscle cell proliferation	BP	0.112	0.00533	0.0242	1.62	0.0157	Igf1/Ddr2/Tert/Mmp2/Cdh13/Adamts1/Htr1b/Stat5b/Irak4/Calcrl/Pdgfrb/Myc	12
GO:0071456	cellular response to hypoxia	BP	0.112	0.00533	0.0242	1.62	0.0157	Kcnk3/Kcnd2/Ddah1/Cbs/Tert/Slc8a3/Scn2a/Ndnf/Cpeb1/Hif3a/Myc/Twist1	12
GO:0030225	macrophage differentiation	BP	0.156	0.00534	0.0242	1.62	0.0157	Hcls1/Plcb1/Calca/Enpp1/Zbtb46/Nrros/Cd4	7
GO:0021543	pallium development	BP	0.0982	0.00542	0.0245	1.61	0.0159	Mdk/Lef1/Zeb2/Cdh2/Dab1/Id4/Fut10/Gli3/Plcb1/Tsku/Dclk2/Lhx6/Nr2f1/Fat4/Bbs1/Psen1	16
GO:0021954	central nervous system neuron development	BP	0.117	0.00543	0.0246	1.61	0.0159	Map2/Dcc/Zeb2/Nrp1/Tsku/Cdh11/Ndnf/Dclk2/Nin/Lhx6/Draxin	11
GO:0015749	monosaccharide transmembrane transport	BP	0.107	0.0055	0.0248	1.6	0.0161	Igf1/Slc2a3/Tert/Gpc3/Stxbp4/Sh2b2/Enpp1/Ednra/Slc23a2/Pid1/Grb10/Myc/Irs1	13
GO:0015837	amine transport	BP	0.107	0.0055	0.0248	1.6	0.0161	Grik1/Syt13/Abat/Myo5a/Grin2b/Cxcl12/Htr1b/Syt7/Htr2a/Ptger3/Psen1/Gabbr1/Cacna1a	13
GO:0044106	cellular amine metabolic process	BP	0.107	0.0055	0.0248	1.6	0.0161	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Hdc/Agtr1a/Ednra/Atp2b4/Slc7a7/Sult1a1/Hand2	13
GO:0055007	cardiac muscle cell differentiation	BP	0.101	0.00552	0.0249	1.6	0.0161	AW551984/Sgcd/Col14a1/Igf1/Adra1a/Slc8a1/Mef2c/Nox4/Tbx3/Arrb2/Pi16/Sgcb/Pdgfrb/Hey2/Hand2	15
GO:2001056	positive regulation of cysteine-type endopeptidase activity	BP	0.101	0.00552	0.0249	1.6	0.0161	Bok/Wdr35/Grin2b/Ift57/Ppm1f/Hip1/Arrb1/Dlc1/Asph/Fyn/Nlrp1b/Ccn2/Cyfip2/F2r/Myc	15
GO:0030902	hindbrain development	BP	0.0955	0.00557	0.0251	1.6	0.0163	Gli1/Mdk/Lef1/Nog/Igf1/Cbs/Dab1/B4galt2/Serpine2/Zfp423/Cplane1/Smad9/Dlc1/Ttbk2/Cacna1a/Bmp7/Zfp365	17
GO:0031646	positive regulation of nervous system process	BP	0.14	0.00567	0.0255	1.59	0.0165	Hgf/Igf1/Abat/Wasf3/Nlgn3/Tppp/Prkar1b/Nlgn2	8
GO:0035567	non-canonical Wnt signaling pathway	BP	0.14	0.00567	0.0255	1.59	0.0165	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Daam2/Fzd2/Dact1	8
GO:0090263	positive regulation of canonical Wnt signaling pathway	BP	0.111	0.00574	0.0258	1.59	0.0167	Sfrp2/Sema5a/Zeb2/Gpc3/Lrrk2/Gprc5b/Peg12/Daam2/Caprin2/Adgra2/Cav1/Dact1	12
GO:0045913	positive regulation of carbohydrate metabolic process	BP	0.122	0.00587	0.0263	1.58	0.017	Igf1/Has2/Pth1r/Igf2/Adcyap1r1/Htr2a/Zbtb20/Psen1/Myc/Irs1	10
GO:0070830	bicellular tight junction assembly	BP	0.122	0.00587	0.0263	1.58	0.017	Wnt11/Cldn8/Cdh5/Esam/Pecam1/Snai1/Nphp1/Cldn5/Pdcd6ip/Cldn1	10
GO:0009063	cellular amino acid catabolic process	BP	0.116	0.00588	0.0263	1.58	0.017	Ddah1/Abat/Nos3/Cbs/Asrgl1/Fah/Amdhd1/Hdc/Atp2b4/Sardh/Prodh	11
GO:0045685	regulation of glial cell differentiation	BP	0.116	0.00588	0.0263	1.58	0.017	Ptprz1/Mdk/Nog/Dab1/Id4/Serpine2/Daam2/Bin1/Ptn/Enpp2/Zfp365	11
GO:0061053	somite development	BP	0.116	0.00588	0.0263	1.58	0.017	Ihh/Sfrp2/Lef1/Wnt11/Nog/Zeb2/Foxf1/Lfng/Loxl3/Ptch1/Psen1	11
GO:0009117	nucleotide metabolic process	BP	0.0761	0.00593	0.0265	1.58	0.0171	Nme4/Acsl6/Igf1/Hmgcs2/Nos3/Acacb/Lrrk2/Adcy3/Them5/Gucy1b1/Gucy1a1/Adcy4/Dhtkd1/Adcy7/Enpp1/Lacc1/Htr2a/Acot7/Zbtb20/Sarm1/Pde5a/Rab23/Nt5c3b/Acsl1/Impdh1/Dpyd/Psen1/Pid1/Pfkm/Cacnb4/Myc/Papss2/Suclg2/Acot6	34
GO:0035116	embryonic hindlimb morphogenesis	BP	0.171	0.00597	0.0266	1.58	0.0172	Aff3/Gpc3/Osr2/Tbx3/Osr1/Twist1	6
GO:0042908	xenobiotic transport	BP	0.171	0.00597	0.0266	1.58	0.0172	Abcg2/Abca8b/Abcb1a/Abcc5/Abcg3/Cldn1	6
GO:0045987	positive regulation of smooth muscle contraction	BP	0.171	0.00597	0.0266	1.58	0.0172	Npnt/Adra1a/Abat/Kit/Ptger3/F2r	6
GO:0090162	establishment of epithelial cell polarity	BP	0.171	0.00597	0.0266	1.58	0.0172	Foxf1/Myo9a/Msn/Frmd4b/Sh3bp1/Frmd4a	6
GO:0001990	regulation of systemic arterial blood pressure by hormone	BP	0.152	0.00604	0.0267	1.57	0.0173	Nos3/Ednrb/Enpep/Edn3/Rps6ka2/Agtr1a/F2r	7
GO:0031952	regulation of protein autophosphorylation	BP	0.152	0.00604	0.0267	1.57	0.0173	Enpp1/Vegfc/Epha7/Rassf2/Cav1/Rap2a/Eng	7
GO:0042417	dopamine metabolic process	BP	0.152	0.00604	0.0267	1.57	0.0173	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Agtr1a	7
GO:0007413	axonal fasciculation	BP	0.2	0.00605	0.0267	1.57	0.0173	Ptprz1/Sema5a/Nrp1/Ndn/Epha3	5
GO:0010996	response to auditory stimulus	BP	0.2	0.00605	0.0267	1.57	0.0173	Stra6/Slc1a3/Mdk/Atp1a2/Ptn	5
GO:0035024	negative regulation of Rho protein signal transduction	BP	0.2	0.00605	0.0267	1.57	0.0173	Adra1a/Rasip1/Arap3/Heg1/Dlc1	5
GO:0036010	protein localization to endosome	BP	0.2	0.00605	0.0267	1.57	0.0173	Nrp1/Msn/Mgat3/Akap11/Ankrd13a	5
GO:0106030	neuron projection fasciculation	BP	0.2	0.00605	0.0267	1.57	0.0173	Ptprz1/Sema5a/Nrp1/Ndn/Epha3	5
GO:0008212	mineralocorticoid metabolic process	BP	0.25	0.00608	0.0267	1.57	0.0173	Ednrb/Dkk3/Kcnma1/Cacna1h	4
GO:0031650	regulation of heat generation	BP	0.25	0.00608	0.0267	1.57	0.0173	Abat/Ednrb/Ptger3/Apln	4
GO:0034433	steroid esterification	BP	0.25	0.00608	0.0267	1.57	0.0173	Soat1/Agtr1a/Apoe/Abcg1	4
GO:0034434	sterol esterification	BP	0.25	0.00608	0.0267	1.57	0.0173	Soat1/Agtr1a/Apoe/Abcg1	4
GO:0034435	cholesterol esterification	BP	0.25	0.00608	0.0267	1.57	0.0173	Soat1/Agtr1a/Apoe/Abcg1	4
GO:0038065	collagen-activated signaling pathway	BP	0.25	0.00608	0.0267	1.57	0.0173	Ddr2/Col4a6/Enpp1/Col4a5	4
GO:0043084	penile erection	BP	0.25	0.00608	0.0267	1.57	0.0173	Ar/Drd4/Ednrb/Ednra	4
GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	BP	0.25	0.00608	0.0267	1.57	0.0173	Cd44/Snai1/Pcbp4/Twist1	4
GO:2000479	regulation of cAMP-dependent protein kinase activity	BP	0.25	0.00608	0.0267	1.57	0.0173	Pkia/Pkib/Atp2b4/Prkar1b	4
GO:0051346	negative regulation of hydrolase activity	BP	0.0792	0.00609	0.0267	1.57	0.0173	Hgf/Sfrp2/Cd109/Spink1/Igf1/Tfpi/Nos3/Cd44/Gpc3/Lrrk2/Mical1/Serpine2/Wfdc3/Serpini1/Wnt9a/Pecam1/Bin1/Nckap1l/Cmya5/Arrb1/Hdac9/Arrb2/Pi16/Angptl4/Simc1/Ppp1r26/Pi15/Gpsm1/Wfdc1	29
GO:0009306	protein secretion	BP	0.0777	0.0062	0.0271	1.57	0.0176	Cacna1c/Igf1/Abat/Drd4/Ednrb/Myo5a/Ano1/Cacna1e/Stxbp4/Rab34/Vegfc/Cd38/Agtr1a/Apoe/Syt7/Cd200/Arrb1/Rcn3/Neo1/P3h1/Abcg1/Frmd4a/Ptger3/Sri/Nr1h3/Pfkm/Golph3l/F2r/Nlgn2/Plek/Irs1	31
GO:0046324	regulation of glucose import	BP	0.129	0.0062	0.0271	1.57	0.0176	Igf1/Tert/Gpc3/Sh2b2/Enpp1/Pid1/Grb10/Myc/Irs1	9
GO:0050885	neuromuscular process controlling balance	BP	0.129	0.0062	0.0271	1.57	0.0176	Ankfn1/Slc1a3/Jph4/Myo5a/Kcnma1/Foxs1/Dlg4/Cacna1a/Nlgn2	9
GO:0007254	JNK cascade	BP	0.0944	0.00622	0.0272	1.57	0.0176	Sfrp2/Eda2r/Lrrk2/Mapk8ip1/Plcb1/Grik2/Cracr2a/Hipk2/Mapkbp1/Rassf2/Irak4/Ccn2/Cdc42ep5/Map4k2/Dact1/Edar/Rap2a	17
GO:0051147	regulation of muscle cell differentiation	BP	0.0993	0.00624	0.0272	1.56	0.0177	Igf1/Mef2c/Hopx/Zeb1/Tshz3/Kit/Cth/Igf2/Hdac9/Arrb2/Pi16/Rbpms2/Efemp2/Camk1/Eng	15
GO:1900180	regulation of protein localization to nucleus	BP	0.0993	0.00624	0.0272	1.56	0.0177	Angpt1/Hcls1/Fermt2/Tert/Prkd1/Tek/Gli3/Pkia/Dclk2/Fyn/Rab23/Lats2/Psen1/Glis2/Cacnb4	15
GO:0042542	response to hydrogen peroxide	BP	0.106	0.00631	0.0275	1.56	0.0178	Cyp1b1/Hgf/Ddr2/Lrrk2/Mmp2/Trpc6/Ednra/Net1/Fyn/Pdgfrb/Pde8a/Pld2/Setx	13
GO:0043030	regulation of macrophage activation	BP	0.138	0.00631	0.0275	1.56	0.0178	Pla2g10/Lrrk2/Slc7a2/Cd1d1/Havcr2/Cd200/Cd84/Nr1h3	8
GO:1902808	positive regulation of cell cycle G1/S phase transition	BP	0.138	0.00631	0.0275	1.56	0.0178	Gli1/Ddr2/Tbx2/Tert/Ccnd2/Adamts1/Plcb1/Stxbp4	8
GO:0042633	hair cycle	BP	0.102	0.00632	0.0275	1.56	0.0178	Apcdd1/Pla2g10/Cd109/Ptch2/Fst/Tert/Edaradd/Myo5a/Ldb2/Tsku/Snai1/Psen1/Edar/Lrp4	14
GO:0044344	cellular response to fibroblast growth factor stimulus	BP	0.115	0.00636	0.0276	1.56	0.0179	Hhip/Nog/Tbx2/Cd44/Enpp1/Ndnf/Ccn2/Apln/Fat4/Kif16b/Setx	11
GO:0035592	establishment of protein localization to extracellular region	BP	0.0775	0.00642	0.0279	1.55	0.0181	Cacna1c/Igf1/Abat/Drd4/Ednrb/Myo5a/Ano1/Cacna1e/Stxbp4/Rab34/Vegfc/Cd38/Agtr1a/Apoe/Syt7/Cd200/Arrb1/Rcn3/Neo1/P3h1/Abcg1/Frmd4a/Ptger3/Sri/Nr1h3/Pfkm/Golph3l/F2r/Nlgn2/Plek/Irs1	31
GO:0050708	regulation of protein secretion	BP	0.0822	0.0066	0.0286	1.54	0.0186	Igf1/Abat/Drd4/Ano1/Cacna1e/Stxbp4/Rab34/Vegfc/Cd38/Apoe/Syt7/Cd200/Arrb1/Neo1/P3h1/Abcg1/Frmd4a/Ptger3/Sri/Nr1h3/Pfkm/Golph3l/F2r/Nlgn2/Irs1	25
GO:0046620	regulation of organ growth	BP	0.105	0.00675	0.0293	1.53	0.019	Gli1/Cacna1c/Col14a1/Nog/Igf1/Tbx2/Acacb/Mef2c/Flvcr1/Igf2/Pi16/Lats2/Hey2	13
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	BP	0.127	0.0068	0.0294	1.53	0.0191	Npr3/Drd4/Akap12/Htr1b/Ednra/Gnaz/Palm/Gabbr1/S1pr3	9
GO:0017156	calcium-ion regulated exocytosis	BP	0.127	0.0068	0.0294	1.53	0.0191	Syn2/Cacna1c/Syt13/Rims3/Stx1b/Cadps/Syt7/Cacna1h/Cacna1a	9
GO:0035307	positive regulation of protein dephosphorylation	BP	0.149	0.00681	0.0294	1.53	0.0191	Itga1/Cdh5/Ppp1r16b/Magi2/Dlc1/Smpd1/Pdgfrb	7
GO:1903524	positive regulation of blood circulation	BP	0.149	0.00681	0.0294	1.53	0.0191	Adra1a/Edn3/Ptger3/Ccn2/Apln/Hey2/Ptger2	7
GO:0010922	positive regulation of phosphatase activity	BP	0.167	0.00688	0.0297	1.53	0.0192	Npnt/Mef2c/Itga1/Magi2/Pdgfrb/Plek	6
GO:0048009	insulin-like growth factor receptor signaling pathway	BP	0.167	0.00688	0.0297	1.53	0.0192	Ar/Igf1/Plcb1/Igfbp4/Grb10/Irs1	6
GO:0009416	response to light stimulus	BP	0.081	0.00689	0.0297	1.53	0.0193	Slc1a3/Sema5a/Cacna1c/Nog/Sema5b/Mmp2/Slc24a4/B4galt2/Pde1b/Cacna1e/Eif2ak4/Fbxl21/Kit/Mme/Rp1/Nlgn3/Arrb1/Nfatc4/Gnb5/Ddhd2/Atp1a2/Syngap1/Brsk1/Smpd1/Usp2/Cacnb4	26
GO:0051260	protein homooligomerization	BP	0.0934	0.00693	0.0299	1.52	0.0193	Kcnb2/Kcna6/Kcnd2/Evl/Kcnd3/Acacb/Ikzf4/Cth/Kcnc4/Mpp2/Pkd2/Nlrp1b/Aqp11/Kcng4/Steap4/Pdcd6ip/Kctd12	17
GO:2001259	positive regulation of cation channel activity	BP	0.119	0.00695	0.0299	1.52	0.0194	Cacna2d1/Ank2/Nlgn3/Cracr2a/Ednra/Stac2/Asph/Pkd2/Gstm7/Cacnb4	10
GO:0007528	neuromuscular junction development	BP	0.136	0.007	0.0301	1.52	0.0195	Pdzrn3/P2rx2/Lrrk2/Ptn/Cacnb4/F2r/Lrp4/Col4a5	8
GO:0071622	regulation of granulocyte chemotaxis	BP	0.136	0.007	0.0301	1.52	0.0195	Mdk/Jam3/Ednra/Dysf/Nckap1l/Xcl1/Tnfaip6/Mpp1	8
GO:1903793	positive regulation of anion transport	BP	0.136	0.007	0.0301	1.52	0.0195	Grik1/Pla2g10/Tcaf1/Abat/Grin2b/Psen1/Abcb1a/Gabbr1	8
GO:0034599	cellular response to oxidative stress	BP	0.0839	0.00704	0.0302	1.52	0.0196	Cyp1b1/Hgf/Ddr2/Slc8a1/Nos3/Lrrk2/Mmp2/Prkd1/Tbc1d24/Trpc6/Aifm2/Prr5l/Ednra/Selenon/Net1/Fyn/Mgat3/Stx2/Pdgfrb/Meak7/Pde8a/Setx/Fbln5	23
GO:0030859	polarized epithelial cell differentiation	BP	0.192	0.0072	0.0308	1.51	0.02	Foxf1/Myo9a/Msn/Sh3bp1/Dlg5	5
GO:0043171	peptide catabolic process	BP	0.192	0.0072	0.0308	1.51	0.02	Enpep/Cpe/Trhde/Ggt7/Lvrn	5
GO:0060065	uterus development	BP	0.192	0.0072	0.0308	1.51	0.02	Stra6/Hoxa11/Hoxa10/Cdkn1c/Hoxa9	5
GO:1902473	regulation of protein localization to synapse	BP	0.192	0.0072	0.0308	1.51	0.02	Gpc6/Nlgn1/Nlgn3/Magi2/Nlgn2	5
GO:0007259	receptor signaling pathway via JAK-STAT	BP	0.0909	0.00733	0.0313	1.5	0.0203	Stra6/Cyp1b1/Agap2/Ptprd/Igf1/Hcls1/Dab1/Kit/Agtr1a/Pecam1/Pkd1/Stat5b/Pkd2/Fyn/Csf2rb/Il12rb1/Cav1/Il7r	18
GO:0030705	cytoskeleton-dependent intracellular transport	BP	0.0909	0.00733	0.0313	1.5	0.0203	Map2/Fez1/Tub/Ccdc88a/Myo5a/Wdr35/Ppfia2/Ift57/Kif1a/Dlg2/Dync2h1/Ttc26/Arl3/Myo1f/Dync2li1/Bbs1/Ift81/Kif5a	18
GO:0071774	response to fibroblast growth factor	BP	0.112	0.00741	0.0316	1.5	0.0205	Hhip/Nog/Tbx2/Cd44/Enpp1/Ndnf/Ccn2/Apln/Fat4/Kif16b/Setx	11
GO:0045428	regulation of nitric oxide biosynthetic process	BP	0.125	0.00745	0.0317	1.5	0.0205	Igf1/Ddah1/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	9
GO:0046579	positive regulation of Ras protein signal transduction	BP	0.125	0.00745	0.0317	1.5	0.0205	Igf1/Lpar4/Dock2/Kitl/Arrb1/Net1/Mapre2/Pdgfrb/F2r	9
GO:0048168	regulation of neuronal synaptic plasticity	BP	0.125	0.00745	0.0317	1.5	0.0205	Grik1/Kdr/Nog/Grin2b/Kit/Grik2/Dlg4/Syngap1/Cpeb1	9
GO:2000179	positive regulation of neural precursor cell proliferation	BP	0.125	0.00745	0.0317	1.5	0.0205	Gli1/Mdk/Nog/Igf1/Zfp423/Gli3/Lrp2/Vegfc/Nes	9
GO:0001843	neural tube closure	BP	0.107	0.00764	0.0321	1.49	0.0208	Sfrp2/Nog/Zeb2/Ift57/Lrp2/Cecr2/Prickle1/Dlc1/Ptch1/Rab23/Fzd2/Twist1	12
GO:1905477	positive regulation of protein localization to membrane	BP	0.107	0.00764	0.0321	1.49	0.0208	Tcaf1/Myo5a/Epha3/Tnfaip6/Stac2/Fyn/Dlg4/Atp2b4/Ptn/Nkd2/Lrp4/Nlgn2	12
GO:0002295	T-helper cell lineage commitment	BP	0.235	0.00765	0.0321	1.49	0.0208	Loxl3/Batf/Spn/Ly9	4
GO:0003184	pulmonary valve morphogenesis	BP	0.235	0.00765	0.0321	1.49	0.0208	Stra6/Nos3/Heyl/Hey2	4
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	BP	0.235	0.00765	0.0321	1.49	0.0208	Nog/Heyl/Snai1/Eng	4
GO:0003222	ventricular trabecula myocardium morphogenesis	BP	0.235	0.00765	0.0321	1.49	0.0208	Ccm2l/Heg1/Hey2/Eng	4
GO:0006491	N-glycan processing	BP	0.235	0.00765	0.0321	1.49	0.0208	St8sia2/St8sia4/Man2a2/St8sia6	4
GO:0035337	fatty-acyl-CoA metabolic process	BP	0.235	0.00765	0.0321	1.49	0.0208	Acsl6/Them5/Acot7/Acsl1	4
GO:0042756	drinking behavior	BP	0.235	0.00765	0.0321	1.49	0.0208	Slc24a4/Htr1b/Agtr1a/Apln	4
GO:0045059	positive thymic T cell selection	BP	0.235	0.00765	0.0321	1.49	0.0208	Cd3g/Dock2/Cd1d1/Zap70	4
GO:0051132	NK T cell activation	BP	0.235	0.00765	0.0321	1.49	0.0208	Cd1d1/Il12rb1/Myc/Rasal3	4
GO:0061000	negative regulation of dendritic spine development	BP	0.235	0.00765	0.0321	1.49	0.0208	Nlgn1/Nlgn3/Apoe/Ngef	4
GO:0061308	cardiac neural crest cell development involved in heart development	BP	0.235	0.00765	0.0321	1.49	0.0208	Ednra/Bmp7/Hand2/Twist1	4
GO:0070571	negative regulation of neuron projection regeneration	BP	0.235	0.00765	0.0321	1.49	0.0208	Thy1/Rtn4rl1/Neo1/Xylt1	4
GO:0090136	epithelial cell-cell adhesion	BP	0.235	0.00765	0.0321	1.49	0.0208	Ihh/Cyp1b1/Kit/Svep1	4
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	BP	0.235	0.00765	0.0321	1.49	0.0208	Ppp1r16b/Aplnr/Jcad/Agtr1a	4
GO:0010718	positive regulation of epithelial to mesenchymal transition	BP	0.146	0.00765	0.0321	1.49	0.0208	Mdk/Lef1/Fermt2/Snai1/Bmp7/Twist1/Eng	7
GO:0006753	nucleoside phosphate metabolic process	BP	0.0747	0.00769	0.0322	1.49	0.0209	Nme4/Acsl6/Igf1/Hmgcs2/Nos3/Acacb/Lrrk2/Adcy3/Them5/Gucy1b1/Gucy1a1/Adcy4/Dhtkd1/Adcy7/Enpp1/Lacc1/Htr2a/Acot7/Zbtb20/Sarm1/Pde5a/Rab23/Nt5c3b/Acsl1/Impdh1/Dpyd/Psen1/Pid1/Pfkm/Cacnb4/Myc/Papss2/Suclg2/Acot6	34
GO:0009308	amine metabolic process	BP	0.103	0.0077	0.0322	1.49	0.0209	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Hdc/Agtr1a/Ednra/Atp2b4/Slc7a7/Sult1a1/Hand2	13
GO:0018958	phenol-containing compound metabolic process	BP	0.103	0.0077	0.0322	1.49	0.0209	Maob/Zeb2/Abat/Drd4/Myo5a/Pde1b/Maoa/Fah/Hdc/Agtr1a/Ednra/Sult1a1/Hand2	13
GO:1901605	alpha-amino acid metabolic process	BP	0.0924	0.0077	0.0322	1.49	0.0209	Aspg/Ddah1/Nos3/Cbs/Asrgl1/Gamt/Kyat1/Fah/Amdhd1/Cth/Phgdh/Nox4/Atp2b4/Slc7a7/Asl/Sardh/Prodh	17
GO:0016051	carbohydrate biosynthetic process	BP	0.0905	0.00771	0.0322	1.49	0.0209	Gulo/Igf1/Chst10/B3galnt1/Has2/St3gal2/Pth1r/Enpp1/Igf2/St8sia6/Adcyap1r1/Sord/St6galnac6/Fam3c/St3gal4/Grb10/Plek/Irs1	18
GO:0021515	cell differentiation in spinal cord	BP	0.133	0.00775	0.0323	1.49	0.021	Hoxd10/Gli3/Gdf7/Dync2h1/Tal1/Ptch1/Cacna1a/Draxin	8
GO:0030042	actin filament depolymerization	BP	0.133	0.00775	0.0323	1.49	0.021	Sema5a/Evl/Tmod2/Mical1/Sh3bp1/Scin/Plekhh2/Plek	8
GO:0046717	acid secretion	BP	0.133	0.00775	0.0323	1.49	0.021	Grik1/Abat/Htr1b/Ptger3/Gabbr1/Cacna1a/Cacnb4/Myc	8
GO:0001964	startle response	BP	0.162	0.00789	0.0328	1.48	0.0213	Aph1b/Grin2b/Glrb/Nlgn3/Npas3/Kcnh1	6
GO:0035909	aorta morphogenesis	BP	0.162	0.00789	0.0328	1.48	0.0213	Tbx2/Fkbp10/Efemp2/Pdgfrb/Hey2/Eng	6
GO:0045746	negative regulation of Notch signaling pathway	BP	0.162	0.00789	0.0328	1.48	0.0213	Lfng/Arrb1/Egfl7/Bend6/Bmp7/Hey2	6
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	BP	0.162	0.00789	0.0328	1.48	0.0213	Igf1/Ddr2/Tert/Mmp2/Adamts1/Htr1b	6
GO:0045862	positive regulation of proteolysis	BP	0.0784	0.00793	0.033	1.48	0.0214	Sfrp2/Aph1b/Bok/Lrrk2/Wdr35/Grin2b/Bbs7/Ift57/Ppm1f/Rnft2/Ecscr/Apoe/Hip1/Prickle1/Arrb1/Rcn3/Dlc1/Asph/Fyn/Nlrp1b/Ccn2/Psen1/Cav1/Cyfip2/Nkd2/F2r/Rnf144a/Myc	28
GO:0019935	cyclic-nucleotide-mediated signaling	BP	0.111	0.00799	0.0332	1.48	0.0215	Gnai1/Ednrb/Gucy1a2/Gucy1b1/Gucy1a1/Aplnr/Apoe/Adcyap1r1/Cap2/Rasd2/Ptger3	11
GO:0043299	leukocyte degranulation	BP	0.111	0.00799	0.0332	1.48	0.0215	Foxf1/Coro1a/Kit/Nckap1l/Myo1f/Cd84/Fgr/Rab27a/Lat/Clnk/Pld2	11
GO:0002244	hematopoietic progenitor cell differentiation	BP	0.0941	0.00805	0.0334	1.48	0.0216	Ptprz1/Pygo1/Kdr/Fst/Jam3/Thsd1/Slc8a3/Flt3/Kit/Eml1/Dhtkd1/Kcp/Tal1/Pus7/Psen1/Batf	16
GO:2001234	negative regulation of apoptotic signaling pathway	BP	0.0854	0.00809	0.0336	1.47	0.0218	Hgf/Sfrp2/Ar/Agap2/Nog/Igf1/Nrp1/Cd44/Tert/Bok/Lrrk2/Icam1/Cxcl12/Mapk8ip1/Tnfrsf22/Cth/Snai1/Bdkrb2/Arrb2/Fyn/Psen1	21
GO:0001541	ovarian follicle development	BP	0.123	0.00815	0.0337	1.47	0.0218	Angpt1/Kdr/Mmp2/Lfng/Kit/Kitl/Arrb1/Tnfaip6/Arrb2	9
GO:0061045	negative regulation of wound healing	BP	0.123	0.00815	0.0337	1.47	0.0218	Cd109/Phldb2/Tfpi/Abat/Serpine2/Apoe/Pros1/Ptger3/Wfdc1	9
GO:0010921	regulation of phosphatase activity	BP	0.116	0.00819	0.0338	1.47	0.0219	Npnt/Mef2c/Itga1/Magi2/Nckap1l/Cmya5/Ppp1r26/Pdgfrb/Vcan/Plek	10
GO:0060606	tube closure	BP	0.106	0.00819	0.0338	1.47	0.0219	Sfrp2/Nog/Zeb2/Ift57/Lrp2/Cecr2/Prickle1/Dlc1/Ptch1/Rab23/Fzd2/Twist1	12
GO:0010829	negative regulation of glucose transmembrane transport	BP	0.185	0.0085	0.035	1.46	0.0227	Sh2b2/Enpp1/Pid1/Grb10/Myc	5
GO:0042104	positive regulation of activated T cell proliferation	BP	0.185	0.0085	0.035	1.46	0.0227	Igf1/Il27ra/Igf2/Stat5b/Il12rb1	5
GO:0062009	secondary palate development	BP	0.185	0.0085	0.035	1.46	0.0227	Lef1/Wnt11/Tshz1/Jag2/Fzd2	5
GO:0090382	phagosome maturation	BP	0.185	0.0085	0.035	1.46	0.0227	Rab34/Srpx/Coro1a/Syt7/Rab20	5
GO:1902806	regulation of cell cycle G1/S phase transition	BP	0.0936	0.0085	0.035	1.46	0.0227	Gli1/Myo16/Ddr2/Tbx2/Tert/Ccnd2/Adamts1/Plcb1/Stxbp4/Pkd1/Pkd2/Fhl1/Atp2b4/Dact1/Hacd1/Cacnb4	16
GO:0031641	regulation of myelination	BP	0.131	0.00855	0.0351	1.45	0.0228	Ptprz1/Hgf/Igf1/Cdh2/Wasf3/Ptn/Tppp/Jam2	8
GO:0042551	neuron maturation	BP	0.131	0.00855	0.0351	1.45	0.0228	Epha8/Cspg4/Lrrk2/Ednrb/Dlg2/Cdkn1c/Nfasc/Ednra	8
GO:0140115	export across plasma membrane	BP	0.131	0.00855	0.0351	1.45	0.0228	Kcnd3/Slc8a1/Slc24a4/Abcg2/Slc8a3/Atp1a2/Abcb1a/Abcc5	8
GO:0051348	negative regulation of transferase activity	BP	0.0837	0.00859	0.0352	1.45	0.0228	Sfrp2/Ddr2/Slc8a1/Ptpro/Mapk8ip1/Slc8a3/Pkia/Thy1/Ppm1f/Cdkn1c/Apoe/Rasip1/Ppm1e/Pkib/Heg1/Lats2/Smpd1/Psen1/Cav1/Bmp7/Prkar1b/Lax1	22
GO:1902882	regulation of response to oxidative stress	BP	0.11	0.0086	0.0353	1.45	0.0228	Hgf/Ddr2/Lrrk2/Tbc1d24/Aifm2/Selenon/Fyn/Ggt7/Meak7/Pde8a/Fbln5	11
GO:0006979	response to oxidative stress	BP	0.0758	0.00872	0.0357	1.45	0.0232	Cyp1b1/Hgf/Ddr2/Slc8a1/Nos3/Lrrk2/Mmp2/Prkd1/Tbc1d24/Trpc6/Msrb3/Aifm2/Cd38/Prr5l/Apoe/Ednra/Selenon/Net1/Fyn/Mgat3/Gpx7/Ggt7/Stx2/Psen1/Pdgfrb/Meak7/Cygb/Pde8a/Pld2/Setx/Fbln5	31
GO:0061387	regulation of extent of cell growth	BP	0.102	0.00874	0.0358	1.45	0.0232	Map2/Sema5a/Sema5b/Nrp1/Sema7a/Fn1/Cxcl12/Apoe/Sema3g/Epha7/Sema6a/Ulk2/Draxin	13
GO:0034394	protein localization to cell surface	BP	0.122	0.00889	0.0364	1.44	0.0236	Angpt1/Wnt11/Gga2/Jam3/Ank2/Prrt1/Tmem35a/Nlgn2/Fbln5	9
GO:0051604	protein maturation	BP	0.0785	0.00892	0.0365	1.44	0.0236	Cpxm2/Ihh/Mmp16/Aph1b/Lrrk2/Serpine2/Gli3/Rps6ka2/Cpe/Mme/Ldlrad3/C1rl/Dync2h1/Pcsk5/C1ra/Ptch1/Asph/Tspan5/Ece2/Adam19/Arxes2/Psen1/Naa11/Cyfip2/Nkd2/Myc/Prss12	27
GO:0051048	negative regulation of secretion	BP	0.0891	0.00893	0.0365	1.44	0.0236	Maob/Abat/Drd4/Myo5a/Foxf1/Edn3/Htr1b/Apoe/Cd200/Nckap1l/Neo1/Frmd4a/Cd84/Ptger3/Gabbr1/Nr1h3/F2r/Irs1	18
GO:0046661	male sex differentiation	BP	0.093	0.00896	0.0366	1.44	0.0237	Tex15/Sfrp2/Ar/Kdr/Hoxa11/Hoxa10/Icam1/Tcf21/Lrp2/Tbx3/Rhobtb3/Hoxa9/Smad9/Stat5b/Abcb1a/Lhfpl2	16
GO:0007212	dopamine receptor signaling pathway	BP	0.158	0.00899	0.0366	1.44	0.0237	Nsg2/Drd4/Lrrk2/Nsg1/Palm/Gnb5	6
GO:0045589	regulation of regulatory T cell differentiation	BP	0.158	0.00899	0.0366	1.44	0.0237	Mdk/Cd44/Sox12/Gimap5/Gimap3/Il2rg	6
GO:0060674	placenta blood vessel development	BP	0.158	0.00899	0.0366	1.44	0.0237	Vash1/Syde1/Pkd1/Pkd2/Vash2/Hey2	6
GO:1902003	regulation of amyloid-beta formation	BP	0.158	0.00899	0.0366	1.44	0.0237	Igf1/Rtn1/Slc2a13/Apoe/Bin1/Abcg1	6
GO:1905606	regulation of presynapse assembly	BP	0.158	0.00899	0.0366	1.44	0.0237	Gpc6/Ptprd/Nlgn1/Lrrc4b/Slitrk3/Nlgn2	6
GO:0034614	cellular response to reactive oxygen species	BP	0.0979	0.00912	0.037	1.43	0.024	Cyp1b1/Hgf/Ddr2/Slc8a1/Nos3/Lrrk2/Mmp2/Trpc6/Ednra/Net1/Pdgfrb/Pde8a/Setx/Fbln5	14
GO:0051656	establishment of organelle localization	BP	0.0749	0.00913	0.037	1.43	0.024	Ankfn1/Map2/Fez1/Itga4/Mark1/Nlgn1/Sec16b/Lrrk2/Myo5a/Foxf1/Ppfia2/Kif1a/Kit/Ubxn2b/Lin7a/Crocc/5730455P16Rik/Syne3/Pard3b/Myo1f/Cep19/Cd84/Fgr/Arfgap3/Psen1/Rab27a/Lat/Map4k2/Clnk/Pld2/Pdcd6ip/Kif5a	32
GO:0050772	positive regulation of axonogenesis	BP	0.109	0.00924	0.0375	1.43	0.0243	Sema5a/Plxnb1/Zeb2/Nrp1/Sema7a/Fn1/Cxcl12/Plxnd1/Apoe/Nin/Chodl	11
GO:0060538	skeletal muscle organ development	BP	0.0872	0.00924	0.0375	1.43	0.0243	Stra6/Hoxd10/Ryr1/P2rx2/Hoxd9/Mef2c/Tcf21/Heyl/Igf2/Dysf/Hdac9/Selenon/Large1/Hlf/Zfp689/Cav1/Usp2/Myc/Twist1	19
GO:0008643	carbohydrate transport	BP	0.0949	0.00935	0.0378	1.42	0.0245	Slc5a11/Igf1/Slc2a3/Tert/Gpc3/Stxbp4/Sh2b2/Enpp1/Ednra/Slc23a2/Abcb1a/Pid1/Grb10/Myc/Irs1	15
GO:1901653	cellular response to peptide	BP	0.0799	0.00939	0.038	1.42	0.0246	Itga4/Igf1/Cacna2d1/Myo5a/Ano1/Icam1/Plcb1/Stxbp4/Sh2b2/Enpp1/Agtr1a/Ednra/Igf2/Hdac9/Stat5b/Fyn/Akt3/Psen1/Cav1/Pid1/C1qtnf9/Cacna1a/Cpeb1/Grb10/Irs1	25
GO:0021872	forebrain generation of neurons	BP	0.129	0.00941	0.038	1.42	0.0246	Lef1/Nrp1/Gli3/Ndnf/Dclk2/Lhx6/Ptger3/Bcl11b	8
GO:0046850	regulation of bone remodeling	BP	0.129	0.00941	0.038	1.42	0.0246	Mdk/Inpp4b/Calca/Tnfrsf11b/Cd38/Syt7/Ltbp3/Def8	8
GO:0060711	labyrinthine layer development	BP	0.129	0.00941	0.038	1.42	0.0246	Lef1/Itga4/Vash1/Syde1/Pcdh12/Vash2/Bmp7/Hey2	8
GO:0010470	regulation of gastrulation	BP	0.222	0.00947	0.038	1.42	0.0246	Phldb2/Osr2/Tgif2/Osr1	4
GO:0010644	cell communication by electrical coupling	BP	0.222	0.00947	0.038	1.42	0.0246	Slc8a1/Gjc1/Sri/Cav1	4
GO:0015701	bicarbonate transport	BP	0.222	0.00947	0.038	1.42	0.0246	Car4/Slc4a3/Ptger3/Slc4a8	4
GO:0032230	positive regulation of synaptic transmission, GABAergic	BP	0.222	0.00947	0.038	1.42	0.0246	Grik1/Nlgn1/Adra1a/Nlgn2	4
GO:0033631	cell-cell adhesion mediated by integrin	BP	0.222	0.00947	0.038	1.42	0.0246	Itga4/Npnt/Podxl/Plpp3	4
GO:0035633	maintenance of blood-brain barrier	BP	0.222	0.00947	0.038	1.42	0.0246	Angpt1/Bdkrb2/Cldn5/Abcb1a	4
GO:0061307	cardiac neural crest cell differentiation involved in heart development	BP	0.222	0.00947	0.038	1.42	0.0246	Ednra/Bmp7/Hand2/Twist1	4
GO:0061430	bone trabecula morphogenesis	BP	0.222	0.00947	0.038	1.42	0.0246	Plxnb1/Thbs3/Mmp2/Enpp1	4
GO:1901617	organic hydroxy compound biosynthetic process	BP	0.0855	0.00947	0.038	1.42	0.0246	Apob/Cyp7b1/Zeb2/Hmgcs2/Myo5a/Sptlc3/Pth1r/Pltp/Hdc/Dkk3/Agtr1a/Apoe/Snai1/Adcyap1r1/Ipmk/Abcg1/Cacna1h/Hand2/Abcg4/Plek	20
GO:0050819	negative regulation of coagulation	BP	0.14	0.00956	0.0383	1.42	0.0248	Tfpi/Abat/Serpine2/Procr/Apoe/Pros1/Ptger3	7
GO:0021675	nerve development	BP	0.114	0.00958	0.0384	1.42	0.0249	Slc1a3/Itga4/Rnf165/Nrp1/Slc24a4/Nptx1/Serpine2/Gli3/Hoxd3/Ednra	10
GO:0048839	inner ear development	BP	0.0868	0.00968	0.0387	1.41	0.0251	Col11a1/Igf1/Tbx2/Lrig3/Gli3/Zeb1/Jag2/Cecr2/Lin7a/Tsku/Tbx3/Kcnma1/Dchs1/Fzd2/Fat4/Kcnq4/Itga8/Ror1/Hey2	19
GO:0042130	negative regulation of T cell proliferation	BP	0.12	0.00968	0.0387	1.41	0.0251	Ihh/Cd44/H2-Ab1/Btla/Havcr2/Pde5a/H2-Aa/Dlg5/Spn	9
GO:0010657	muscle cell apoptotic process	BP	0.108	0.00992	0.0396	1.4	0.0256	Sfrp2/Gria4/Mdk/Igf1/Rps6ka2/Agtr1a/Arrb1/Arrb2/Cav1/Hey2/Hand2	11
GO:0034390	smooth muscle cell apoptotic process	BP	0.179	0.00994	0.0396	1.4	0.0256	Gria4/Igf1/Agtr1a/Arrb1/Arrb2	5
GO:0034391	regulation of smooth muscle cell apoptotic process	BP	0.179	0.00994	0.0396	1.4	0.0256	Gria4/Igf1/Agtr1a/Arrb1/Arrb2	5
GO:0045822	negative regulation of heart contraction	BP	0.179	0.00994	0.0396	1.4	0.0256	Adra1a/Bin1/Pde5a/Atp1a2/Sri	5
GO:0061298	retina vasculature development in camera-type eye	BP	0.179	0.00994	0.0396	1.4	0.0256	Ndp/Cyp1b1/Nrp1/Arhgef15/Pdgfrb	5
GO:1903055	positive regulation of extracellular matrix organization	BP	0.179	0.00994	0.0396	1.4	0.0256	Sema5a/Ddr2/Phldb2/Emilin1/Efemp2	5
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	BP	0.179	0.00994	0.0396	1.4	0.0256	Drd4/Mef2c/Rgs5/Efemp2/Apln	5
GO:0001773	myeloid dendritic cell activation	BP	0.154	0.0102	0.0403	1.39	0.0261	Dock2/Havcr2/Gimap5/Gimap3/Psen1/Batf	6
GO:0002335	mature B cell differentiation	BP	0.154	0.0102	0.0403	1.39	0.0261	Itm2a/Lfng/Dock10/Enpp1/Irf8/Mfng	6
GO:0032885	regulation of polysaccharide biosynthetic process	BP	0.154	0.0102	0.0403	1.39	0.0261	Igf1/Has2/Enpp1/Igf2/Grb10/Irs1	6
GO:0033238	regulation of cellular amine metabolic process	BP	0.154	0.0102	0.0403	1.39	0.0261	Maob/Abat/Drd4/Pde1b/Atp2b4/Slc7a7	6
GO:0070570	regulation of neuron projection regeneration	BP	0.154	0.0102	0.0403	1.39	0.0261	Hgf/Thy1/Rtn4rl1/Neo1/Xylt1/Ptn	6
GO:0002315	marginal zone B cell differentiation	BP	0.3	0.0103	0.0403	1.39	0.0261	Lfng/Dock10/Mfng	3
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	BP	0.3	0.0103	0.0403	1.39	0.0261	Gimap5/Gimap3/Il2rg	3
GO:0002692	negative regulation of cellular extravasation	BP	0.3	0.0103	0.0403	1.39	0.0261	Cxcl12/Plcb1/Il27ra	3
GO:0021957	corticospinal tract morphogenesis	BP	0.3	0.0103	0.0403	1.39	0.0261	Zeb2/Cdh11/Nin	3
GO:0035864	response to potassium ion	BP	0.3	0.0103	0.0403	1.39	0.0261	Nptx1/Dlg2/Dlg4	3
GO:0035865	cellular response to potassium ion	BP	0.3	0.0103	0.0403	1.39	0.0261	Nptx1/Dlg2/Dlg4	3
GO:0043201	response to leucine	BP	0.3	0.0103	0.0403	1.39	0.0261	Klhl22/Rragd/Ubr1	3
GO:0045199	maintenance of epithelial cell apical/basal polarity	BP	0.3	0.0103	0.0403	1.39	0.0261	Wnt11/Lin7a/Pdcd6ip	3
GO:0051001	negative regulation of nitric-oxide synthase activity	BP	0.3	0.0103	0.0403	1.39	0.0261	Atp2b4/Cav1/Eng	3
GO:0060513	prostatic bud formation	BP	0.3	0.0103	0.0403	1.39	0.0261	Ar/Nog/Bmp7	3
GO:0060982	coronary artery morphogenesis	BP	0.3	0.0103	0.0403	1.39	0.0261	Nrp1/Lrp2/Hand2	3
GO:0070294	renal sodium ion absorption	BP	0.3	0.0103	0.0403	1.39	0.0261	Ednrb/Maged2/Ednra	3
GO:0071233	cellular response to leucine	BP	0.3	0.0103	0.0403	1.39	0.0261	Klhl22/Rragd/Ubr1	3
GO:0090269	fibroblast growth factor production	BP	0.3	0.0103	0.0403	1.39	0.0261	Wnt11/Ccm2l/Heg1	3
GO:0090270	regulation of fibroblast growth factor production	BP	0.3	0.0103	0.0403	1.39	0.0261	Wnt11/Ccm2l/Heg1	3
GO:0099640	axo-dendritic protein transport	BP	0.3	0.0103	0.0403	1.39	0.0261	Myo5a/Dlg2/Kif5a	3
GO:1900119	positive regulation of execution phase of apoptosis	BP	0.3	0.0103	0.0403	1.39	0.0261	Bok/Cxcr3/Dlc1	3
GO:1902746	regulation of lens fiber cell differentiation	BP	0.3	0.0103	0.0403	1.39	0.0261	Zeb2/Cdkn1c/Spred3	3
GO:0097696	receptor signaling pathway via STAT	BP	0.0878	0.0103	0.0403	1.39	0.0261	Stra6/Cyp1b1/Agap2/Ptprd/Igf1/Hcls1/Dab1/Kit/Agtr1a/Pecam1/Pkd1/Stat5b/Pkd2/Fyn/Csf2rb/Il12rb1/Cav1/Il7r	18
GO:0046486	glycerolipid metabolic process	BP	0.0761	0.0103	0.0403	1.39	0.0261	Apob/Acsl6/Pla2g10/Efr3b/Pip5k1b/Inpp4b/Plcb1/Them5/Ttc7b/Dgkb/Apoe/Bpnt1/Htr2a/Lpcat1/Plcb2/Plpp1/Ddhd2/Abhd8/Acsl1/Pdgfrb/Cav1/Nr1h3/Lipe/Pld2/Enpp2/Plek/Mboat2/Cds1/Abhd3	29
GO:0042269	regulation of natural killer cell mediated cytotoxicity	BP	0.127	0.0103	0.0403	1.39	0.0261	Pik3r6/Cd226/Havcr2/Igf2/Arrb2/Stat5b/Gimap5/Gimap3	8
GO:0048260	positive regulation of receptor-mediated endocytosis	BP	0.127	0.0103	0.0403	1.39	0.0261	Angpt1/Magi2/Sele/Hip1/Arrb1/Arrb2/Apln/Pld2	8
GO:2000401	regulation of lymphocyte migration	BP	0.127	0.0103	0.0403	1.39	0.0261	Itga4/Cxcl12/Msn/Il27ra/Cd200/Xcl1/Spn/Jam2	8
GO:0046323	glucose import	BP	0.112	0.0103	0.0403	1.39	0.0261	Igf1/Slc2a3/Tert/Gpc3/Sh2b2/Enpp1/Pid1/Grb10/Myc/Irs1	10
GO:0009314	response to radiation	BP	0.0742	0.0104	0.0404	1.39	0.0261	Slc1a3/Sfrp2/Sema5a/Cacna1c/Nog/Sema5b/Ccnd2/Mmp2/Slc24a4/B4galt2/Pde1b/Cacna1e/Eif2ak4/Lrp2/Fbxl21/Kit/Mme/Rp1/Nlgn3/Arrb1/Nfatc4/Net1/Gnb5/Ddhd2/Atp1a2/Syngap1/Brsk1/Smpd1/Usp2/Ints3/Cacnb4/Myc	32
GO:0046822	regulation of nucleocytoplasmic transport	BP	0.0992	0.0105	0.0408	1.39	0.0264	Angpt1/Hcls1/Inpp4b/Prkd1/Tek/Gli3/Pkia/Peg12/Dnajc27/Wipf1/Rab23/Psen1/Camk1	13
GO:0051592	response to calcium ion	BP	0.0992	0.0105	0.0408	1.39	0.0264	Nlgn1/Syt13/Cpne5/Mef2c/Rasgrp2/Syt7/Kcnma1/Asph/Pkd2/Slc25a23/Smpd1/Cav1/Kcnh1	13
GO:0002704	negative regulation of leukocyte mediated immunity	BP	0.118	0.0105	0.0408	1.39	0.0264	Foxf1/Havcr2/Igf2/Nckap1l/Arrb2/Cd84/Cd96/Spn/Il7r	9
GO:0021766	hippocampus development	BP	0.118	0.0105	0.0408	1.39	0.0264	Mdk/Lef1/Zeb2/Dab1/Id4/Gli3/Tsku/Dclk2/Bbs1	9
GO:0080164	regulation of nitric oxide metabolic process	BP	0.118	0.0105	0.0408	1.39	0.0264	Igf1/Ddah1/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	9
GO:1903036	positive regulation of response to wounding	BP	0.118	0.0105	0.0408	1.39	0.0264	Mdk/Ddr2/Fermt2/Plpp3/Clec7a/St3gal4/Ptn/Cldn1/F2r	9
GO:0032886	regulation of microtubule-based process	BP	0.0821	0.0106	0.0409	1.39	0.0265	Map2/Fez1/Phldb2/Mpdz/Gnai1/Cdh5/Map9/Epha3/Rp1/Tubb4a/Dysf/Pkd1/Nin/Slain1/Klhl42/Ttbk2/Cep97/Bbs1/Mapre2/Cav1/Tppp/Pdcd6ip	22
GO:0006687	glycosphingolipid metabolic process	BP	0.137	0.0106	0.0411	1.39	0.0266	St8sia2/St8sia4/St3gal2/St6galnac4/Kit/St8sia6/St6galnac6	7
GO:0045933	positive regulation of muscle contraction	BP	0.137	0.0106	0.0411	1.39	0.0266	Npnt/Adra1a/Abat/Kit/Ptger3/Ccn2/F2r	7
GO:0030593	neutrophil chemotaxis	BP	0.107	0.0106	0.0411	1.39	0.0266	Cxcl15/Mdk/Jam3/Edn3/Itga1/Ednra/Dysf/Nckap1l/Xcl1/Tnfaip6/Mpp1	11
GO:0019218	regulation of steroid metabolic process	BP	0.103	0.0107	0.0412	1.39	0.0267	Apob/Igf1/Kit/Dkk3/Agtr1a/Apoe/Kcnma1/Igf2/Snai1/Abcg1/Stat5b/Abcg4	12
GO:1904659	glucose transmembrane transport	BP	0.103	0.0107	0.0412	1.39	0.0267	Igf1/Slc2a3/Tert/Gpc3/Stxbp4/Sh2b2/Enpp1/Ednra/Pid1/Grb10/Myc/Irs1	12
GO:0008645	hexose transmembrane transport	BP	0.102	0.0114	0.0436	1.36	0.0283	Igf1/Slc2a3/Tert/Gpc3/Stxbp4/Sh2b2/Enpp1/Ednra/Pid1/Grb10/Myc/Irs1	12
GO:0007173	epidermal growth factor receptor signaling pathway	BP	0.106	0.0114	0.0436	1.36	0.0283	Fam83a/Ccdc88a/Areg/Cdh13/Itga1/Hip1/Rassf2/Afap1l2/Mvb12b/Psen1/Kif16b	11
GO:0002090	regulation of receptor internalization	BP	0.117	0.0114	0.0436	1.36	0.0283	Angpt1/Drd4/Magi2/Sele/Arrb1/Arrb2/Dlg4/Apln/Ankrd13a	9
GO:0005977	glycogen metabolic process	BP	0.117	0.0114	0.0436	1.36	0.0283	Igf1/Pygm/Pcdh12/Enpp1/Igf2/Grb10/Pfkm/Pygl/Irs1	9
GO:0006073	cellular glucan metabolic process	BP	0.117	0.0114	0.0436	1.36	0.0283	Igf1/Pygm/Pcdh12/Enpp1/Igf2/Grb10/Pfkm/Pygl/Irs1	9
GO:0098661	inorganic anion transmembrane transport	BP	0.117	0.0114	0.0436	1.36	0.0283	Slc1a3/Slc12a8/Ano1/Ano2/Glrb/Gabra4/Slc12a4/Slc4a8/Ank	9
GO:0032232	negative regulation of actin filament bundle assembly	BP	0.15	0.0115	0.0436	1.36	0.0283	Kank4/Phldb2/Arhgap6/Tmeff2/Dlc1/Arhgap28	6
GO:0050850	positive regulation of calcium-mediated signaling	BP	0.15	0.0115	0.0436	1.36	0.0283	Kdr/Igf1/Cdh13/Itgal/Zap70/Cd4	6
GO:0060219	camera-type eye photoreceptor cell differentiation	BP	0.15	0.0115	0.0436	1.36	0.0283	Ihh/Sdk2/Thy1/Rp1/Rorb/Ptn	6
GO:0060351	cartilage development involved in endochondral bone morphogenesis	BP	0.15	0.0115	0.0436	1.36	0.0283	Ihh/Hoxd11/Thbs3/Cbs/Hoxa11/Stc1	6
GO:1902624	positive regulation of neutrophil migration	BP	0.15	0.0115	0.0436	1.36	0.0283	Mdk/Ednra/Dysf/Nckap1l/Xcl1/Ptger3	6
GO:1903580	positive regulation of ATP metabolic process	BP	0.15	0.0115	0.0436	1.36	0.0283	Igf1/Htr2a/Zbtb20/Psen1/Pid1/Myc	6
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	BP	0.15	0.0115	0.0436	1.36	0.0283	Cd83/Nckap1l/Xcl1/Gimap5/Gimap3/Il2rg	6
GO:0002827	positive regulation of T-helper 1 type immune response	BP	0.211	0.0115	0.0436	1.36	0.0283	H2-Ab1/Il27ra/Xcl1/Il12rb1	4
GO:0003228	atrial cardiac muscle tissue development	BP	0.211	0.0115	0.0436	1.36	0.0283	Nog/Tbx3/Ednra/Eng	4
GO:0010523	negative regulation of calcium ion transport into cytosol	BP	0.211	0.0115	0.0436	1.36	0.0283	Calca/Pkd2/Gstm7/Sri	4
GO:0010544	negative regulation of platelet activation	BP	0.211	0.0115	0.0436	1.36	0.0283	Abat/Serpine2/Apoe/Ptger3	4
GO:0022038	corpus callosum development	BP	0.211	0.0115	0.0436	1.36	0.0283	Zeb2/Tsku/Nin/Rtn4rl1	4
GO:0032570	response to progesterone	BP	0.211	0.0115	0.0436	1.36	0.0283	Acod1/Cav1/Nr1h3/Ptger2	4
GO:0033604	negative regulation of catecholamine secretion	BP	0.211	0.0115	0.0436	1.36	0.0283	Abat/Myo5a/Ptger3/Gabbr1	4
GO:0034111	negative regulation of homotypic cell-cell adhesion	BP	0.211	0.0115	0.0436	1.36	0.0283	Abat/Serpine2/Ccm2l/Ptger3	4
GO:0035461	vitamin transmembrane transport	BP	0.211	0.0115	0.0436	1.36	0.0283	Stra6/Lrp2/Slc23a2/Abcc5	4
GO:0045198	establishment of epithelial cell apical/basal polarity	BP	0.211	0.0115	0.0436	1.36	0.0283	Foxf1/Myo9a/Msn/Sh3bp1	4
GO:0045579	positive regulation of B cell differentiation	BP	0.211	0.0115	0.0436	1.36	0.0283	Prdm1/Nckap1l/Stat5b/Il2rg	4
GO:0071514	genomic imprinting	BP	0.211	0.0115	0.0436	1.36	0.0283	H19/Tet1/Ndn/Cdkn1c	4
GO:0033198	response to ATP	BP	0.172	0.0115	0.0436	1.36	0.0283	Ryr1/Slc8a1/P2rx2/Enpp1/Asph	5
GO:0042133	neurotransmitter metabolic process	BP	0.172	0.0115	0.0436	1.36	0.0283	Maob/Abat/Maoa/Naalad2/Bche	5
GO:0060571	morphogenesis of an epithelial fold	BP	0.172	0.0115	0.0436	1.36	0.0283	Ar/Nog/Gdf7/Cecr2/Bmp7	5
GO:0061311	cell surface receptor signaling pathway involved in heart development	BP	0.172	0.0115	0.0436	1.36	0.0283	Wnt11/Nog/Snai1/Hey2/Hand2	5
GO:0090023	positive regulation of neutrophil chemotaxis	BP	0.172	0.0115	0.0436	1.36	0.0283	Mdk/Ednra/Dysf/Nckap1l/Xcl1	5
GO:0060291	long-term synaptic potentiation	BP	0.0824	0.0119	0.0448	1.35	0.029	Nog/Nlgn1/Grin2b/Serpine2/Shank2/Eif2ak4/Slc8a3/Tshz3/Mme/Nlgn3/Enpp1/Nrgn/Apoe/Prrt1/Nsg1/Nfatc4/Cyp46a1/Mpp2/Psen1/Ptn/Prkar1b	21
GO:0044242	cellular lipid catabolic process	BP	0.0848	0.0121	0.0457	1.34	0.0296	Apob/Cyp1b1/Pla2g10/Acacb/Plcb1/Bdh2/Echs1/Acot7/Ddhd2/Abcd2/Smpd1/Lipe/Pld2/Enpp2/Plbd1/Twist1/Abhd3/Echdc2/Irs1	19
GO:0050764	regulation of phagocytosis	BP	0.101	0.0121	0.0457	1.34	0.0296	Tub/Dock2/Syt7/Cnn2/Dysf/Pros1/Nckap1l/Masp1/Fgr/Clec7a/Rab27a/Il2rg	12
GO:0044042	glucan metabolic process	BP	0.115	0.0124	0.0466	1.33	0.0302	Igf1/Pygm/Pcdh12/Enpp1/Igf2/Grb10/Pfkm/Pygl/Irs1	9
GO:0045453	bone resorption	BP	0.115	0.0124	0.0466	1.33	0.0302	Ihh/Calca/Pth1r/Enpp1/Tnfrsf11b/Cd38/Nox4/Ltbp3/Def8	9
GO:0009247	glycolipid biosynthetic process	BP	0.123	0.0124	0.0466	1.33	0.0302	St8sia2/St8sia4/St3gal2/St6galnac4/St8sia6/Sccpdh/St6galnac6/St3gal4	8
GO:0071260	cellular response to mechanical stimulus	BP	0.123	0.0124	0.0466	1.33	0.0302	Wnt11/Nos3/Cnn2/Ednra/Habp4/Atp1a2/Piezo2/Cav1	8
GO:0051222	positive regulation of protein transport	BP	0.0779	0.0126	0.0473	1.32	0.0307	Igf1/Tcaf1/Abat/Hcls1/Ano1/Prkd1/Tek/Gli3/Lrp2/Rab34/Vegfc/Cd38/Prr5l/Arrb1/Abcg1/Asph/Frmd4a/Fyn/Wipf1/Psen1/Sri/Pfkm/Golph3l/Camk1/Nlgn2	25
GO:0050672	negative regulation of lymphocyte proliferation	BP	0.109	0.0129	0.0483	1.32	0.0313	Ihh/Cd44/Prdm1/H2-Ab1/Btla/Havcr2/Pde5a/H2-Aa/Dlg5/Spn	10
GO:1900182	positive regulation of protein localization to nucleus	BP	0.109	0.0129	0.0483	1.32	0.0313	Hcls1/Fermt2/Tert/Prkd1/Tek/Gli3/Fyn/Psen1/Glis2/Cacnb4	10
GO:0035850	epithelial cell differentiation involved in kidney development	BP	0.146	0.013	0.0486	1.31	0.0315	Ptpro/Ednrb/Mef2c/Ednra/Osr1/Fat4	6
GO:2000772	regulation of cellular senescence	BP	0.146	0.013	0.0486	1.31	0.0315	Tbx2/Tert/Abi3/Vash1/Akt3/Twist1	6
GO:0072091	regulation of stem cell proliferation	BP	0.132	0.013	0.0487	1.31	0.0316	Fermt2/Tert/Vegfc/Tbx3/Kitl/Ltbp3/Septin4	7
GO:2000677	regulation of transcription regulatory region DNA binding	BP	0.132	0.013	0.0487	1.31	0.0316	Igf1/Zc4h2/Psen1/Sri/Hey2/Hand2/Twist1	7
GO:0001911	negative regulation of leukocyte mediated cytotoxicity	BP	0.167	0.0133	0.0495	1.3	0.0321	Havcr2/Igf2/Nckap1l/Arrb2/Il7r	5
GO:0001963	synaptic transmission, dopaminergic	BP	0.167	0.0133	0.0495	1.3	0.0321	Slc6a2/Aph1b/Drd4/Arrb2/Rasd2	5
GO:0005979	regulation of glycogen biosynthetic process	BP	0.167	0.0133	0.0495	1.3	0.0321	Igf1/Enpp1/Igf2/Grb10/Irs1	5
GO:0010962	regulation of glucan biosynthetic process	BP	0.167	0.0133	0.0495	1.3	0.0321	Igf1/Enpp1/Igf2/Grb10/Irs1	5
GO:0051957	positive regulation of amino acid transport	BP	0.167	0.0133	0.0495	1.3	0.0321	Grik1/Abat/Grin2b/Psen1/Gabbr1	5
GO:1903523	negative regulation of blood circulation	BP	0.167	0.0133	0.0495	1.3	0.0321	Adra1a/Bin1/Pde5a/Atp1a2/Sri	5
GO:0045776	negative regulation of blood pressure	BP	0.121	0.0135	0.0499	1.3	0.0323	Kdr/Adra1a/Abat/Nos3/Calca/Vegfc/Bdkrb2/Apln	8
GO:0060688	regulation of morphogenesis of a branching structure	BP	0.121	0.0135	0.0499	1.3	0.0323	Hgf/Ar/Mdk/Nog/Lrrk2/Cpe/Agtr1a/Bmp7	8
GO:0090311	regulation of protein deacetylation	BP	0.121	0.0135	0.0499	1.3	0.0323	Lrrk2/Prkd1/Tcf21/Ndn/Aplnr/Dysf/Tada2a/Tppp	8
GO:1903307	positive regulation of regulated secretory pathway	BP	0.121	0.0135	0.0499	1.3	0.0323	Nlgn1/Cadps/Syt7/Cacna1h/Fgr/Slc4a8/Rab27a/Pld2	8
GO:0030879	mammary gland development	BP	0.0909	0.0136	0.0499	1.3	0.0323	Ar/Lef1/Agap2/Igf1/Tbx2/Hoxd9/Areg/Foxf1/Gli3/Tbx3/Hoxa9/Ptch1/Stat5b/Cav1/Irs1	15
GO:0002318	myeloid progenitor cell differentiation	BP	0.273	0.0137	0.0499	1.3	0.0323	Jam3/Flt3/Kit	3
GO:0003139	secondary heart field specification	BP	0.273	0.0137	0.0499	1.3	0.0323	Wnt11/Mef2c/Lrp2	3
GO:0006171	cAMP biosynthetic process	BP	0.273	0.0137	0.0499	1.3	0.0323	Adcy3/Adcy4/Adcy7	3
GO:0007158	neuron cell-cell adhesion	BP	0.273	0.0137	0.0499	1.3	0.0323	Nlgn1/Nlgn3/Nlgn2	3
GO:0009415	response to water	BP	0.273	0.0137	0.0499	1.3	0.0323	Pkd2/Atp2b4/Sipa1	3
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	BP	0.273	0.0137	0.0499	1.3	0.0323	Gli1/Igf1/Zfp423	3
GO:0030202	heparin metabolic process	BP	0.273	0.0137	0.0499	1.3	0.0323	Angpt1/Ednrb/Ednra	3
GO:0032815	negative regulation of natural killer cell activation	BP	0.273	0.0137	0.0499	1.3	0.0323	Havcr2/Fgr/Clnk	3
GO:0034454	microtubule anchoring at centrosome	BP	0.273	0.0137	0.0499	1.3	0.0323	Ninl/Nin/Cep19	3
GO:0035090	maintenance of apical/basal cell polarity	BP	0.273	0.0137	0.0499	1.3	0.0323	Wnt11/Lin7a/Pdcd6ip	3
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	BP	0.273	0.0137	0.0499	1.3	0.0323	Ar/Igf1/Igfbp4	3
GO:0051135	positive regulation of NK T cell activation	BP	0.273	0.0137	0.0499	1.3	0.0323	Cd1d1/Il12rb1/Rasal3	3
GO:0060405	regulation of penile erection	BP	0.273	0.0137	0.0499	1.3	0.0323	Ar/Drd4/Ednrb	3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	BP	0.273	0.0137	0.0499	1.3	0.0323	Nrp1/Areg/Plxnd1	3
GO:0071372	cellular response to follicle-stimulating hormone stimulus	BP	0.273	0.0137	0.0499	1.3	0.0323	Epha8/Epha3/Ednra	3
GO:0072102	glomerulus morphogenesis	BP	0.273	0.0137	0.0499	1.3	0.0323	Mef2c/Tcf21/Pdgfrb	3
GO:0072178	nephric duct morphogenesis	BP	0.273	0.0137	0.0499	1.3	0.0323	Gpc3/Epha7/Osr1	3
GO:0086016	AV node cell action potential	BP	0.273	0.0137	0.0499	1.3	0.0323	Cacna1c/Scn4b/Ank2	3
GO:0086027	AV node cell to bundle of His cell signaling	BP	0.273	0.0137	0.0499	1.3	0.0323	Cacna1c/Scn4b/Ank2	3
GO:0090184	positive regulation of kidney development	BP	0.273	0.0137	0.0499	1.3	0.0323	Nog/Ednra/Myc	3
GO:0099545	trans-synaptic signaling by trans-synaptic complex	BP	0.273	0.0137	0.0499	1.3	0.0323	Efnb3/Ptprd/Nlgn1	3
GO:1902946	protein localization to early endosome	BP	0.273	0.0137	0.0499	1.3	0.0323	Nrp1/Msn/Mgat3	3
GO:1903564	regulation of protein localization to cilium	BP	0.273	0.0137	0.0499	1.3	0.0323	Ccdc88a/Crocc/Dzip1	3
GO:2000344	positive regulation of acrosome reaction	BP	0.273	0.0137	0.0499	1.3	0.0323	Pla2g10/Plcb1/Cacna1h	3
GO:0097060	synaptic membrane	CC	0.192	1.58e-24	8.5e-22	21.1	5.62e-22	Efnb3/Ptprz1/Kcnj3/Grid1/Gria4/Cacna1c/Grik1/Lrrc4c/Slc6a2/Kcnd2/Dcc/Ptprd/Kcnd3/Grid2ip/Nlgn1/Slc8a1/Nrp1/Ptpro/Rims3/Stx1b/P2rx2/Cdh2/Lrrc4b/Grin2b/Shank2/Cacna1e/Adgrl1/Ank2/Slitrk3/Col13a1/Syde1/Htr1b/Cpe/Glrb/Scn2a/Gabra4/Dlg2/Grik2/Lin7a/Nlgn3/Dgkb/Sorcs2/Prrt1/Syt7/Prrt2/Kcnma1/Hip1/Zc4h2/Arrb1/Septin3/Pcdh17/Nsg1/Epha7/Cacng7/Arrb2/Mpp2/Erc2/Lrfn2/Cacna1h/Magee1/Dlg4/Palm/Slc4a8/Stx2/Psen1/Gabbr1/Ntng1/Sspn/Itga8/Iqsec3/F2r/Lrp4/Kcnh1/Kctd12/Nlgn2	75
GO:0062023	collagen-containing extracellular matrix	CC	0.179	1.89e-21	5.08e-19	18.3	3.36e-19	Ndp/Gpc6/Col11a1/Ptprz1/Hmcn1/Vit/Angpt1/Emid1/Col14a1/Colec12/Igf1/Col4a6/Thbs3/Npnt/Lamc3/Lama4/Spock2/Cspg4/Col16a1/Tgfbi/Gpc3/Fn1/Angptl2/Nid1/Serpine2/Egflam/Adamts1/Col9a2/Col13a1/Frem1/Mamdc2/Postn/Loxl3/Adamts10/Smoc1/Mgp/Lama2/Matn2/Emilin1/Sparcl1/Tmeff2/Igf2/Col5a2/Ltbp3/Bgn/Col15a1/Adamtsl1/P3h1/Vwa1/Abi3bp/Dpt/Adam19/Angptl4/Efemp2/Egfl7/Plxdc2/Ptn/Ntng1/Col23a1/Col18a1/Gpc2/Adamts17/Itgb4/Spn/Lum/Nid2/Bmp7/Vcan/Ccdc80/Fbln5/Col4a5	71
GO:0045211	postsynaptic membrane	CC	0.194	6.73e-18	1.21e-15	14.9	7.98e-16	Ptprz1/Grid1/Gria4/Cacna1c/Grik1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Grid2ip/Nlgn1/Slc8a1/Nrp1/Ptpro/Cdh2/Lrrc4b/Grin2b/Shank2/Cacna1e/Ank2/Slitrk3/Col13a1/Glrb/Gabra4/Dlg2/Grik2/Lin7a/Nlgn3/Dgkb/Sorcs2/Prrt1/Prrt2/Kcnma1/Hip1/Zc4h2/Arrb1/Pcdh17/Nsg1/Epha7/Cacng7/Arrb2/Mpp2/Lrfn2/Cacna1h/Magee1/Dlg4/Gabbr1/Sspn/Iqsec3/F2r/Kcnh1/Kctd12/Nlgn2	53
GO:0098978	glutamatergic synapse	CC	0.161	4.36e-14	5.87e-12	11.2	3.88e-12	Efnb3/Syn2/Grid1/Gria4/Lrrc4c/Begain/Kcnd2/Ptprd/Nlgn1/Nrp1/Ptpro/Drd4/Wasf3/Lrrk2/Lrrc4b/Myo5a/Pfn2/Nptx1/Grin2b/Plcb1/Ppfia2/Abi2/Coro1a/Gucy1a1/Scn2a/Dlg2/Cadps/Grik2/Dgkb/Nptxr/Apoe/Cdh11/Syt7/Prrt2/Sparcl1/Pcdh17/Nsg1/Epha7/Cacng7/Mpp2/Erc2/Cpt1c/Cacna1h/Dlg4/Syngap1/Slc4a8/Ngef/Nrn1/Ntng1/Cacna1a/Cacnb4/Prkar1b	52
GO:0098984	neuron to neuron synapse	CC	0.152	8.6e-14	9.25e-12	11	6.12e-12	Gap43/Efnb3/Syn2/Map2/Grid1/Gria4/Cacna1c/Grik1/Lrrc4c/Kcnd2/Dcc/Ptprd/Kcnd3/Epb41l3/Slc8a1/Lrrc7/Ptpro/P2rx2/Cdh2/Lrrc4b/Dab1/Grin2b/Shank2/Rps6kc1/Adgrl1/Ank2/Slc8a3/Slitrk3/Dlg2/Grik2/Nrgn/Sorcs2/Prrt1/Cap2/Arrb1/Cacng7/Pdzd2/Arrb2/Ptch1/Mpp2/Erc2/Lrfn2/Fyn/Cnn3/Dlg4/Palm/Dlg5/Syngap1/Slc4a8/Arhgef9/Cpeb1/Itga8/Iqsec3/Prkar1b/Lrp4	55
GO:0099572	postsynaptic specialization	CC	0.153	1.09e-13	9.73e-12	11	6.44e-12	Gap43/Syn2/Map2/Grid1/Gria4/Cacna1c/Grik1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Epb41l3/Slc8a1/Lrrc7/Ptpro/P2rx2/Cdh2/Lrrc4b/Dab1/Grin2b/Shank2/Rps6kc1/Adgrl1/Ank2/Slc8a3/Slitrk3/Dlg2/Grik2/Nlgn3/Nrgn/Sorcs2/Prrt1/Cap2/Arrb1/Cacng7/Pdzd2/Arrb2/Ptch1/Mpp2/Erc2/Lrfn2/Fyn/Cnn3/Dlg4/Palm/Dlg5/Syngap1/Arhgef9/Cpeb1/Itga8/Iqsec3/Lrp4/Nlgn2	54
GO:0032279	asymmetric synapse	CC	0.153	3.12e-13	1.86e-11	10.7	1.23e-11	Gap43/Syn2/Map2/Grid1/Gria4/Cacna1c/Grik1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Epb41l3/Slc8a1/Lrrc7/Ptpro/P2rx2/Cdh2/Lrrc4b/Dab1/Grin2b/Shank2/Rps6kc1/Adgrl1/Ank2/Slc8a3/Slitrk3/Dlg2/Grik2/Nrgn/Sorcs2/Prrt1/Cap2/Arrb1/Cacng7/Pdzd2/Arrb2/Ptch1/Mpp2/Erc2/Lrfn2/Fyn/Cnn3/Dlg4/Palm/Dlg5/Syngap1/Slc4a8/Arhgef9/Cpeb1/Itga8/Iqsec3/Lrp4	52
GO:0014069	postsynaptic density	CC	0.155	3.92e-13	2.11e-11	10.7	1.39e-11	Gap43/Syn2/Map2/Grid1/Gria4/Cacna1c/Grik1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Epb41l3/Slc8a1/Lrrc7/Ptpro/P2rx2/Cdh2/Lrrc4b/Dab1/Grin2b/Shank2/Rps6kc1/Adgrl1/Ank2/Slc8a3/Slitrk3/Dlg2/Grik2/Nrgn/Sorcs2/Prrt1/Cap2/Arrb1/Cacng7/Pdzd2/Arrb2/Ptch1/Mpp2/Erc2/Lrfn2/Fyn/Cnn3/Dlg4/Palm/Dlg5/Syngap1/Arhgef9/Cpeb1/Itga8/Iqsec3/Lrp4	51
GO:0042383	sarcolemma	CC	0.206	9.35e-13	4.32e-11	10.4	2.86e-11	Kcnj3/Car4/Cacna1c/Sgcd/Kcnd2/Ryr1/Adra1a/Slc8a1/Nos3/Cdh2/Scn1a/Cacna2d1/Ank2/Slc8a3/Msn/Scn2a/Lama2/Ednra/Itga7/Dysf/Bin1/Bgn/Cacng7/Flnc/Ryr3/Cacna1h/Atp2b4/Sgcb/Atp1a2/Psen1/Sri/Cav1/Sspn/Pld2	34
GO:0098857	membrane microdomain	CC	0.142	9.65e-13	4.32e-11	10.4	2.86e-11	Cacna1c/Angpt1/Kcnd2/Dcc/Kdr/Kcnd3/Tfpi/Nos3/Rgs16/Gnai1/Cdh2/Lrrk2/Ednrb/Ano1/Icam1/Abcg2/Adcy3/Tek/Cdh13/Has2/Tnfrsf22/Gprc5b/Itga1/Lrp2/Thy1/Plpp3/Cpe/Mme/Kcnma1/Sele/Ednra/Pecam1/Dysf/Adcyap1r1/Cavin3/Rtn4rl1/Dlc1/Ptch1/Fyn/Cacna1h/Cavin2/Plpp1/Atp1a2/Zap70/Stx2/Psen1/Gabbr1/Cav1/Abcg3/Lipe/Pld2/Lcp2/F2r/Cd4/Lrp4/Irs1	56
GO:0042734	presynaptic membrane	CC	0.227	1.42e-12	5.87e-11	10.2	3.88e-11	Efnb3/Kcnj3/Cacna1c/Grik1/Slc6a2/Ptprd/Rims3/Stx1b/P2rx2/Cdh2/Grin2b/Cacna1e/Adgrl1/Htr1b/Scn2a/Grik2/Syt7/Prrt2/Kcnma1/Hip1/Septin3/Pcdh17/Erc2/Cacna1h/Slc4a8/Stx2/Gabbr1/Ntng1/Kcnh1/Kctd12	30
GO:0045121	membrane raft	CC	0.14	2.88e-12	1.03e-10	9.99	6.84e-11	Cacna1c/Angpt1/Kcnd2/Dcc/Kdr/Kcnd3/Tfpi/Nos3/Rgs16/Gnai1/Cdh2/Lrrk2/Ednrb/Ano1/Icam1/Abcg2/Adcy3/Tek/Cdh13/Has2/Tnfrsf22/Gprc5b/Itga1/Lrp2/Thy1/Plpp3/Cpe/Mme/Kcnma1/Sele/Ednra/Pecam1/Adcyap1r1/Cavin3/Rtn4rl1/Dlc1/Ptch1/Fyn/Cacna1h/Cavin2/Plpp1/Atp1a2/Zap70/Stx2/Psen1/Gabbr1/Cav1/Abcg3/Lipe/Pld2/Lcp2/F2r/Cd4/Lrp4/Irs1	55
GO:0005604	basement membrane	CC	0.227	1.93e-11	6.1e-10	9.21	4.03e-10	Hmcn1/Col4a6/Npnt/Lamc3/Lama4/Tgfbi/Fn1/Nid1/Egflam/Adamts1/Frem1/Smoc1/Lama2/Matn2/Tmeff2/Col15a1/P3h1/Vwa1/Efemp2/Ptn/Ntng1/Col18a1/Itgb4/Spn/Nid2/Ccdc80/Col4a5	27
GO:0034703	cation channel complex	CC	0.165	9.29e-11	2.78e-09	8.56	1.84e-09	Kcnb2/Kcnj3/Gria4/Cacna1c/Grik1/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/Cachd1/Scn1a/Cacna2d1/Kcnq5/Grin2b/Cacna1e/Unc80/Trpc6/Scn2a/Grik2/Kcnma1/Kcnc4/Pkd1/Cacng7/Kcnip3/Pkd2/Ryr3/Cpt1c/Cacna1h/Dlg4/Kcng4/Scn3a/Nrn1/Kcnq4/Cacna1a/Cacnb4/Kcnh1	37
GO:0034702	ion channel complex	CC	0.146	1.66e-10	4.69e-09	8.33	3.1e-09	Kcnb2/Kcnj3/Gria4/Cacna1c/Grik1/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/Cachd1/Scn1a/Cacna2d1/Kcnq5/Ano1/Grin2b/Cacna1e/Ano2/Unc80/Ttyh2/Trpc6/Glrb/Scn2a/Gabra4/Grik2/Kcnma1/Kcnc4/Pkd1/Cacng7/Kcnip3/Pkd2/Ryr3/Cpt1c/Cacna1h/Dlg4/Kcng4/Scn3a/Nrn1/Kcnq4/Cacna1a/Lrrc8c/Cacnb4/Kcnh1	43
GO:0099240	intrinsic component of synaptic membrane	CC	0.211	2.4e-10	6.47e-09	8.19	4.28e-09	Efnb3/Kcnj3/Grid1/Lrrc4c/Kcnd2/Dcc/Ptprd/Kcnd3/Nlgn1/Nrp1/Ptpro/Cdh2/Lrrc4b/Grin2b/Cacna1e/Slitrk3/Htr1b/Scn2a/Nlgn3/Prrt2/Pcdh17/Mpp2/Lrfn2/Cacna1h/Ntng1/Nlgn2	26
GO:0099699	integral component of synaptic membrane	CC	0.212	1.06e-09	2.58e-08	7.59	1.71e-08	Efnb3/Kcnj3/Grid1/Lrrc4c/Kcnd2/Dcc/Ptprd/Kcnd3/Nlgn1/Nrp1/Ptpro/Cdh2/Lrrc4b/Grin2b/Cacna1e/Slitrk3/Htr1b/Scn2a/Nlgn3/Prrt2/Pcdh17/Lrfn2/Cacna1h/Nlgn2	24
GO:0005901	caveola	CC	0.229	1.13e-09	2.65e-08	7.58	1.75e-08	Cacna1c/Kcnd2/Kcnd3/Tfpi/Nos3/Lrrk2/Cdh13/Kcnma1/Sele/Adcyap1r1/Cavin3/Dlc1/Ptch1/Cacna1h/Cavin2/Plpp1/Atp1a2/Cav1/Lipe/Pld2/F2r/Irs1	22
GO:0044853	plasma membrane raft	CC	0.191	2.37e-09	5.31e-08	7.27	3.51e-08	Cacna1c/Kcnd2/Kcnd3/Tfpi/Nos3/Cdh2/Lrrk2/Cdh13/Has2/Kcnma1/Sele/Adcyap1r1/Cavin3/Dlc1/Ptch1/Cacna1h/Cavin2/Plpp1/Atp1a2/Cav1/Lipe/Pld2/Lcp2/F2r/Lrp4/Irs1	26
GO:0005938	cell cortex	CC	0.134	5.57e-09	1.2e-07	6.92	7.93e-08	Hmcn1/Ryr1/Phldb2/Hcls1/Rims3/Drd4/Gnai1/Cdh2/Prkd1/Exoc3l/Gypc/Coro1a/Sh3bp1/Rhobtb3/Sele/Pard6g/Septin3/Dlc1/Pard3b/BC034090/Myo1f/Asph/Pkd2/Erc2/Cldn5/Dlg4/Septin4/Ccn2/Arhgef9/Psen1/Mpp1/Cav1/Plekhh2/Shroom1/Usp2/Itgb4/Septin6/Cd302/Gpsm1/Cytip/Pstpip1	41
GO:0031253	cell projection membrane	CC	0.131	7.45e-09	1.54e-07	6.81	1.02e-07	Gap43/Ptprz1/Map2/Car4/Evc2/Evc/Epb41l3/Cd44/Aif1l/Abcg2/Adcy3/Enpep/Shank2/Bbs7/Podxl/Lrp2/Thy1/Pth1r/Msn/Gabra4/Jcad/Eps8l1/Kcnc4/Dlc1/Tmem231/Mpp2/Pkd2/Fgr/Ptger3/Palm/Bbs1/Plekho1/Abcb1a/Gabbr1/Abcg3/Pld2/Itga8/Nradd/Iqce/Kcnh1/Tbc1d10c/Plek	42
GO:0030027	lamellipodium	CC	0.165	1.03e-08	1.97e-07	6.7	1.31e-07	Ptprz1/Evl/Ccdc88a/Cd44/Cdh2/Wasf3/Abi3/Podxl/Ptprm/Plxnd1/Abi2/Coro1a/Palld/Sh3bp1/Dysf/Kitl/Arap3/Carmil3/Parvb/Pkd2/Fgd1/Unc5c/Arhgap31/Dpysl3/Stx2/Plekhh2/Pld2/Nradd/Plekhg5	29
GO:0043197	dendritic spine	CC	0.157	1.13e-08	2.1e-07	6.68	1.39e-07	Ptprz1/Slc1a3/Gria4/Kcnd2/Kcnd3/Grid2ip/Nlgn1/Slc8a1/Lrrc7/Ptpro/P2rx2/Drd4/Grin2b/Shank2/Ppfia2/Slc8a3/Dock10/Abi2/Nrgn/Sla/Arrb1/Arrb2/Mpp2/Cnn3/Dlg4/Palm/Atp1a2/Sri/Gabbr1/Itga8/Zmynd8	31
GO:0044309	neuron spine	CC	0.153	2.06e-08	3.69e-07	6.43	2.44e-07	Ptprz1/Slc1a3/Gria4/Kcnd2/Kcnd3/Grid2ip/Nlgn1/Slc8a1/Lrrc7/Ptpro/P2rx2/Drd4/Grin2b/Shank2/Ppfia2/Slc8a3/Dock10/Abi2/Nrgn/Sla/Arrb1/Arrb2/Mpp2/Cnn3/Dlg4/Palm/Atp1a2/Sri/Gabbr1/Itga8/Zmynd8	31
GO:0099634	postsynaptic specialization membrane	CC	0.224	2.35e-08	4.08e-07	6.39	2.7e-07	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Ptpro/Cdh2/Lrrc4b/Grin2b/Slitrk3/Dlg2/Nlgn3/Prrt1/Cacng7/Mpp2/Lrfn2/Dlg4/Nlgn2	19
GO:0098936	intrinsic component of postsynaptic membrane	CC	0.213	5.2e-08	8.55e-07	6.07	5.65e-07	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Nrp1/Ptpro/Cdh2/Lrrc4b/Grin2b/Cacna1e/Slitrk3/Nlgn3/Pcdh17/Mpp2/Lrfn2/Cacna1h/Nlgn2	19
GO:0016323	basolateral plasma membrane	CC	0.138	5.52e-08	8.73e-07	6.06	5.77e-07	Slc1a3/Slc13a5/Slc8a1/Lrrc7/Cd44/Cdh2/Tek/Cldn8/Ank2/Pth1r/Plpp3/Msn/Slc29a1/Dlg2/Heph/Lin7a/Cd38/Agtr1a/Slc23a2/Pkd1/Arrb1/Arrb2/Slc38a1/Abca8b/Slco4c1/Palm/Atp2b4/Stx2/Abcc5/Cav1/Nkd2/Cldn1/S100g/Slc43a3	34
GO:1902495	transmembrane transporter complex	CC	0.118	7.51e-08	1.15e-06	5.94	7.63e-07	Kcnb2/Kcnj3/Gria4/Cacna1c/Grik1/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/Cachd1/Scn1a/Cacna2d1/Kcnq5/Ano1/Grin2b/Cacna1e/Ano2/Unc80/Ttyh2/Trpc6/Glrb/Scn2a/Gabra4/Grik2/Kcnma1/Kcnc4/Pkd1/Cacng7/Kcnip3/Pkd2/Ryr3/Cpt1c/Cacna1h/Dlg4/Kcng4/Scn3a/Atp1a2/Nrn1/Kcnq4/Cacna1a/Lrrc8c/Cacnb4/Kcnh1	44
GO:0009925	basal plasma membrane	CC	0.13	1.01e-07	1.51e-06	5.82	9.98e-07	Slc1a3/Slc13a5/Slc8a1/Lrrc7/Cd44/Cdh2/Tek/Cldn8/Ank2/Pth1r/Plpp3/Msn/Slc29a1/Dlg2/Heph/Lin7a/Cd38/Agtr1a/Slc23a2/Pkd1/Arrb1/Arrb2/Slc38a1/Pkd2/Abca8b/Slco4c1/Palm/Atp2b4/Stx2/Abcc5/Cav1/Itgb4/Nkd2/Cldn1/S100g/Slc43a3	36
GO:0099055	integral component of postsynaptic membrane	CC	0.212	1.32e-07	1.84e-06	5.73	1.22e-06	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Nrp1/Ptpro/Cdh2/Lrrc4b/Grin2b/Cacna1e/Slitrk3/Nlgn3/Pcdh17/Lrfn2/Cacna1h/Nlgn2	18
GO:0030133	transport vesicle	CC	0.123	1.34e-07	1.84e-06	5.73	1.22e-06	Syn2/Car4/Igf1/Aph1b/Syt13/Sec16b/Stx1b/Lrrk2/Myo5a/Grin2b/Kif1a/Mme/Dlg2/Lin7a/Dmxl2/Nrgn/Lyz2/Prrt1/Syt7/Prrt2/Kcnc4/Bin1/Synrg/Bgn/Sv2c/Dlg4/Septin4/Lyz1/Dpysl3/Slc4a8/Brsk1/Stx2/Psen1/Rab27a/Gabbr1/Sspn/Nkd2/Septin6/Sipa1	39
GO:0019897	extrinsic component of plasma membrane	CC	0.151	2.13e-07	2.79e-06	5.55	1.85e-06	Ryr1/Fermt2/Gnai1/Cdh2/Cdh6/Serpine2/Cdh13/Gngt2/Cdh10/Cdh5/Gng11/Sla/Apoe/Cdh11/Hip1/Gng2/Stac2/Dchs1/Fyn/Gnaz/Dlg4/Fgr/Gnb5/Gng7/Zap70/Gnb4/Styk1	27
GO:0098948	intrinsic component of postsynaptic specialization membrane	CC	0.238	2.89e-07	3.71e-06	5.43	2.45e-06	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Ptpro/Cdh2/Lrrc4b/Grin2b/Slitrk3/Nlgn3/Mpp2/Lrfn2/Nlgn2	15
GO:0005614	interstitial matrix	CC	0.471	5.47e-07	6.84e-06	5.17	4.52e-06	Vit/Col14a1/Igf1/Egflam/Mamdc2/Vwa1/Abi3bp/Ccdc80	8
GO:0098982	GABA-ergic synapse	CC	0.217	1.02e-06	1.24e-05	4.91	8.23e-06	Kcnd2/Kcnd3/Ptpro/Plcb1/Slitrk3/Glrb/Gucy1a1/Epha3/Syt7/Pcdh17/Erc2/Arhgef9/Gabbr1/Iqsec3/Nlgn2	15
GO:0099060	integral component of postsynaptic specialization membrane	CC	0.23	1.16e-06	1.39e-05	4.86	9.16e-06	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Ptpro/Cdh2/Lrrc4b/Grin2b/Slitrk3/Nlgn3/Lrfn2/Nlgn2	14
GO:0031594	neuromuscular junction	CC	0.187	1.89e-06	2.16e-05	4.67	1.43e-05	Pdzrn3/Stx1b/Lama4/Serpine2/Tbc1d24/Slc8a3/Postn/Dlg2/Lama2/Kcnc4/Itga7/Dlg4/Psen1/Ptn/F2r/Lrp4/Col4a5	17
GO:0043679	axon terminus	CC	0.137	2.36e-06	2.59e-05	4.59	1.71e-05	Gria4/Grik1/Kcna6/Slc8a1/P2rx2/Drd4/Lrrk2/Pfn2/Grin2b/Mical1/Slc8a3/Calca/Grik2/Syt7/Prrt2/Kcnma1/Kcnc4/Bin1/Kcnip3/Erc2/Septin4/Slc4a8/Sri/Septin6/Ror1/Prss12	26
GO:0030426	growth cone	CC	0.133	2.64e-06	2.84e-05	4.55	1.88e-05	Ptprz1/Map2/Fez1/Itga4/Dcc/Nrp1/Tmod2/Lrrk2/Shank2/Mapk8ip1/Adgrl1/Myo9a/Slc2a13/Lrp2/Thy1/Tshz3/Nin/Neo1/Ptch1/Erc2/Pcdhgb1/Unc5c/Dpysl3/Psen1/Cpeb1/Kif5a/Setx	27
GO:0016324	apical plasma membrane	CC	0.108	2.69e-06	2.84e-05	4.55	1.88e-05	Car4/Ddr2/Mpdz/Ptpro/Cd44/P2rx2/Cdh2/Fn1/Slc24a4/Ano1/Abcg2/Enpep/Stc1/Tek/Shank2/Podxl/Lrp2/Thy1/Pth1r/Msn/Slc29a1/Nox4/Kcnma1/Slc23a2/Pard6g/Pard3b/BC034090/Slc38a1/Plpp1/Psen1/Abcb1a/Rab27a/Pdgfrb/Abcc5/Cav1/Shroom1/Pfkm/Cldn1/S100g/Atp6v1b2	40
GO:0098839	postsynaptic density membrane	CC	0.217	5.52e-06	5.5e-05	4.26	3.64e-05	Grid1/Lrrc4c/Dcc/Ptpro/Lrrc4b/Grin2b/Slitrk3/Dlg2/Prrt1/Cacng7/Mpp2/Lrfn2/Dlg4	13
GO:0001726	ruffle	CC	0.144	6.13e-06	6e-05	4.22	3.97e-05	Ptprz1/Map2/Cspg4/Aif1l/Myo5a/Podxl/Sh2b2/Rab34/Frmd4b/Jcad/Eps8l1/Pecam1/Arap3/Tln2/Dlc1/Fgd1/Fgr/Plekho1/Pdgfrb/Fgd2/Plek/Atp6v1b2	22
GO:0098802	plasma membrane signaling receptor complex	CC	0.132	7.41e-06	7.12e-05	4.15	4.71e-05	Gria4/Grik1/Itga4/Itgb7/Grin2b/Cd3g/Itga1/Grik2/Itgal/Il27ra/Emilin1/Itga7/Cacng7/Csf2rb/Cpt1c/Calcrl/Dlg4/Zap70/Apbb1ip/Il12rb1/Gabbr1/Nrn1/Itga8/Itgb4/Irs1	25
GO:0070382	exocytic vesicle	CC	0.123	8.26e-06	7.8e-05	4.11	5.15e-05	Syn2/Igf1/Syt13/Stx1b/Lrrk2/Myo5a/Grin2b/Kif1a/Mme/Dlg2/Dmxl2/Prrt1/Syt7/Prrt2/Kcnc4/Bin1/Sv2c/Dlg4/Septin4/Dpysl3/Slc4a8/Brsk1/Stx2/Psen1/Rab27a/Gabbr1/Nkd2/Septin6	28
GO:0030055	cell-substrate junction	CC	0.132	1.08e-05	1e-04	4	6.61e-05	Hmcn1/Evl/Phldb2/Nrp1/Fermt2/Aif1l/Itgb7/Thsd1/Itga1/Tnfsf13b/Msn/Palld/Sla/Nox4/Itga7/Parvg/Efs/Parvb/Tln2/Dlc1/Mapre2/Cav1/Itgb4/Tle2	24
GO:0098562	cytoplasmic side of membrane	CC	0.128	1.17e-05	0.000107	3.97	7.07e-05	Ryr1/Fermt2/Gnai1/Lrrk2/Rasa3/Gngt2/Msn/Kit/Gng11/Sla/Hip1/Gng2/Stac2/Pkd2/Fyn/Gnaz/Dlg4/Fgr/Gnb5/Gng7/Zap70/Gnb4/Styk1/Ptpn7/Rasal3	25
GO:0005912	adherens junction	CC	0.141	2.17e-05	0.000195	3.71	0.000129	Hmcn1/Fermt2/Cdh2/Cdh6/Cdh10/Ptprm/Cdh5/Msn/Abi2/Frmd4b/Esam/Jcad/Lin7a/Sh3bp1/Cdh11/Pard3b/Dchs1/Frmd4a/Dlg5/Shroom1	20
GO:0034705	potassium channel complex	CC	0.169	2.72e-05	0.00024	3.62	0.000159	Kcnb2/Kcnj3/Gria4/Grik1/Kcna6/Kcnd2/Kcnd3/Kcnq5/Grik2/Kcnma1/Kcnc4/Kcnip3/Kcng4/Kcnq4/Kcnh1	15
GO:0098889	intrinsic component of presynaptic membrane	CC	0.216	3.02e-05	0.000258	3.59	0.000171	Efnb3/Kcnj3/Ptprd/Cdh2/Cacna1e/Htr1b/Scn2a/Prrt2/Pcdh17/Cacna1h/Ntng1	11
GO:0005925	focal adhesion	CC	0.13	3.02e-05	0.000258	3.59	0.000171	Evl/Phldb2/Nrp1/Fermt2/Aif1l/Itgb7/Thsd1/Itga1/Tnfsf13b/Msn/Palld/Sla/Nox4/Parvg/Efs/Parvb/Tln2/Dlc1/Mapre2/Cav1/Itgb4/Tle2	22
GO:0034706	sodium channel complex	CC	0.296	3.21e-05	0.00027	3.57	0.000179	Gria4/Grik1/Scn4b/Scn1a/Scn2a/Grik2/Cacna1h/Scn3a	8
GO:0099056	integral component of presynaptic membrane	CC	0.227	4.29e-05	0.000355	3.45	0.000235	Efnb3/Kcnj3/Ptprd/Cdh2/Cacna1e/Htr1b/Scn2a/Prrt2/Pcdh17/Cacna1h	10
GO:0005923	bicellular tight junction	CC	0.138	4.75e-05	0.000387	3.41	0.000256	Clmp/Mpdz/Jam3/Cldn8/Cdh5/Frmd4b/Esam/Lin7a/Sh3bp1/Magi2/Pard6g/Adcyap1r1/Pard3b/Frmd4a/Nphp1/Cldn5/Pdcd6ip/Cldn1/Jam2	19
GO:0098685	Schaffer collateral - CA1 synapse	CC	0.169	4.96e-05	0.000398	3.4	0.000263	Syn2/Lrrc4c/Dcc/Ptprd/Pfn2/Akap12/Dgkb/Cdh11/Mpp2/Lrfn2/Fyn/Gabbr1/Ntng1/Prkar1b	14
GO:0043296	apical junction complex	CC	0.129	5.3e-05	0.000416	3.38	0.000275	Clmp/Mpdz/Jam3/Cldn8/Cdh5/Frmd4b/Esam/Lin7a/Sh3bp1/Nfasc/Magi2/Pard6g/Adcyap1r1/Pard3b/Frmd4a/Nphp1/Cldn5/Shroom1/Pdcd6ip/Cldn1/Jam2	21
GO:0070160	tight junction	CC	0.132	5.33e-05	0.000416	3.38	0.000275	Clmp/Mpdz/Jam3/Cldn8/Cdh5/Frmd4b/Esam/Lin7a/Sh3bp1/Nfasc/Magi2/Pard6g/Adcyap1r1/Pard3b/Frmd4a/Nphp1/Cldn5/Pdcd6ip/Cldn1/Jam2	20
GO:0009898	cytoplasmic side of plasma membrane	CC	0.124	6.16e-05	0.000466	3.33	0.000308	Ryr1/Fermt2/Gnai1/Rasa3/Gngt2/Msn/Kit/Gng11/Sla/Hip1/Gng2/Stac2/Fyn/Gnaz/Dlg4/Fgr/Gnb5/Gng7/Zap70/Gnb4/Styk1/Ptpn7	22
GO:0036064	ciliary basal body	CC	0.124	6.16e-05	0.000466	3.33	0.000308	Evc/Ccdc88a/Kif7/Dzip1l/Cibar1/Wdr35/Bbs7/Armc9/Ift57/Rilpl1/Cfap410/Ttc26/Arl3/Cep19/Pkd2/Ttbk2/Dzip1/Dlg5/Dync2li1/Bbs1/Ift81/Irs1	22
GO:0098858	actin-based cell projection	CC	0.114	6.62e-05	0.000488	3.31	0.000323	Gap43/Ptprz1/Map2/Angpt1/Nlgn1/Lrrc7/Cd44/Lrrk2/Myo5a/Jam3/Tek/Podxl/Msn/Abi2/Coro1a/Nfasc/Lyz2/Kitl/Myo1f/Unc5c/Lyz1/Palm/Spn/Cd302/Tbc1d10c/Atp6v1b2	26
GO:0043195	terminal bouton	CC	0.156	0.000123	0.000848	3.07	0.000561	Gria4/Grik1/P2rx2/Drd4/Lrrk2/Pfn2/Grin2b/Mical1/Calca/Grik2/Kcnma1/Erc2/Slc4a8/Prss12	14
GO:0099568	cytoplasmic region	CC	0.111	0.000137	0.000925	3.03	0.000612	Gli1/Map2/Phldb2/Rims3/Arl6/Gnai1/Dzip1l/Lrrk2/Wdr35/Bbs7/Dnah5/Gli3/Ift57/Grik2/Rp1/Tubb4a/Dync2h1/Arl3/Pkd2/Erc2/Dnah7b/Dlg4/Dync2li1/Dnah1/Bbs1	25
GO:0099146	intrinsic component of postsynaptic density membrane	CC	0.22	0.000138	0.000925	3.03	0.000612	Grid1/Lrrc4c/Dcc/Ptpro/Lrrc4b/Grin2b/Slitrk3/Mpp2/Lrfn2	9
GO:0008305	integrin complex	CC	0.235	0.000193	0.00128	2.89	0.000849	Itga4/Itgb7/Itga1/Itgal/Emilin1/Itga7/Itga8/Itgb4	8
GO:0008021	synaptic vesicle	CC	0.112	0.000203	0.00133	2.88	0.00088	Syn2/Stx1b/Lrrk2/Myo5a/Grin2b/Kif1a/Mme/Dlg2/Dmxl2/Prrt1/Syt7/Prrt2/Kcnc4/Bin1/Sv2c/Dlg4/Septin4/Slc4a8/Brsk1/Stx2/Psen1/Gabbr1/Septin6	23
GO:0098644	complex of collagen trimers	CC	0.316	0.000218	0.00141	2.85	0.000934	Col11a1/Col4a6/Col16a1/Col5a2/Lum/Col4a5	6
GO:0005790	smooth endoplasmic reticulum	CC	0.229	0.00024	0.00152	2.82	0.001	Map2/Ryr1/Jph4/Rtn1/Myo5a/Ryr3/Psen1/Sri	8
GO:0005834	heterotrimeric G-protein complex	CC	0.229	0.00024	0.00152	2.82	0.001	Gnai1/Gngt2/Gng11/Gng2/Gnaz/Gnb5/Gng7/Gnb4	8
GO:0008076	voltage-gated potassium channel complex	CC	0.16	0.000281	0.0017	2.77	0.00112	Kcnb2/Kcnj3/Kcna6/Kcnd2/Kcnd3/Kcnq5/Kcnma1/Kcnc4/Kcnip3/Kcng4/Kcnq4/Kcnh1	12
GO:0098791	Golgi apparatus subcompartment	CC	0.0977	0.000291	0.00174	2.76	0.00115	B4galnt4/Car4/Nsg2/Chst2/Tgfbi/Bok/Gga2/Lrrk2/Slc9a7/Ap1m1/Prkd1/Postn/Plpp3/Rab34/Mme/Chst1/Cracr2a/Ggta1/Lyz2/Dennd5a/5730455P16Rik/Pcsk5/Ms4a7/Nsg1/Ece2/Lyz1/Xylt1/Vps53/Golph3l/Atp8b4	30
GO:0030175	filopodium	CC	0.141	0.000343	0.00203	2.69	0.00134	Gap43/Ptprz1/Map2/Nlgn1/Lrrc7/Myo5a/Podxl/Msn/Abi2/Kitl/Unc5c/Palm/Cd302/Tbc1d10c	14
GO:1905360	GTPase complex	CC	0.216	0.00036	0.00208	2.68	0.00138	Gnai1/Gngt2/Gng11/Gng2/Gnaz/Gnb5/Gng7/Gnb4	8
GO:0034704	calcium channel complex	CC	0.164	0.000397	0.00227	2.64	0.0015	Cacna1c/Ryr1/Cachd1/Cacna2d1/Cacna1e/Pkd1/Cacng7/Ryr3/Cacna1h/Cacna1a/Cacnb4	11
GO:0099061	integral component of postsynaptic density membrane	CC	0.205	0.000526	0.00298	2.53	0.00197	Grid1/Lrrc4c/Dcc/Ptpro/Lrrc4b/Grin2b/Slitrk3/Lrfn2	8
GO:0097730	non-motile cilium	CC	0.114	0.000588	0.00329	2.48	0.00218	D630045J12Rik/Myo5a/Slc24a4/Tmem237/Shank2/Bbs7/Cerkl/Ano2/Ift57/Rp1/Cfap410/Arl3/Pkd2/Nphp1/Iqcb1/Gnb5/C130074G19Rik/Rab27a/Glis2	19
GO:0097733	photoreceptor cell cilium	CC	0.128	0.000624	0.00346	2.46	0.00229	D630045J12Rik/Myo5a/Slc24a4/Tmem237/Shank2/Bbs7/Cerkl/Ift57/Rp1/Cfap410/Arl3/Nphp1/Iqcb1/Gnb5/Rab27a	15
GO:0016342	catenin complex	CC	0.226	0.000636	0.00349	2.46	0.00231	Cdh2/Cdh6/Cdh13/Cdh10/Cdh5/Cdh11/Dchs1	7
GO:0097731	9+0 non-motile cilium	CC	0.123	0.000659	0.00358	2.45	0.00237	D630045J12Rik/Myo5a/Slc24a4/Tmem237/Shank2/Bbs7/Cerkl/Ift57/Rp1/Cfap410/Arl3/Nphp1/Iqcb1/Gnb5/C130074G19Rik/Rab27a	16
GO:0043292	contractile fiber	CC	0.101	0.00068	0.00366	2.44	0.00242	Cacna1c/Ryr1/Npnt/Adra1a/Slc8a1/Pygm/Tmod2/Scn1a/Mmp2/Mef2c/Grin2b/Arhgef25/Ank2/Palld/Pecam1/Bin1/Myl3/Cmya5/Ryr3/Habp4/Atp2b4/Simc1/Psen1/Sri	24
GO:0032838	plasma membrane bounded cell projection cytoplasm	CC	0.109	0.000767	0.00408	2.39	0.0027	Gli1/Map2/Arl6/Dzip1l/Lrrk2/Wdr35/Bbs7/Dnah5/Gli3/Ift57/Grik2/Rp1/Tubb4a/Dync2h1/Arl3/Dnah7b/Dlg4/Dync2li1/Dnah1/Bbs1	20
GO:0016528	sarcoplasm	CC	0.141	0.000902	0.00476	2.32	0.00315	Car4/Sgcd/Ryr1/Jph4/Pygm/Cacna2d1/Cmya5/Flnc/Asph/Ryr3/Gstm7/Sri	12
GO:0030863	cortical cytoskeleton	CC	0.123	0.000969	0.00506	2.3	0.00335	Hcls1/Rims3/Cdh2/Gypc/Coro1a/Sele/Dlc1/Myo1f/Erc2/Cldn5/Dlg4/Mpp1/Plekhh2/Shroom1/Pstpip1	15
GO:0005874	microtubule	CC	0.0845	0.00104	0.00534	2.27	0.00353	Map2/Fez1/Clmp/Capn6/Slc8a1/Kif7/Cep170/Klhl22/Dnah5/Slc8a3/Kif26a/Kif1a/Reep1/Eml1/Map9/Tubb4a/Katnal1/Apoe/Dync2h1/Ninl/Kif6/Dysf/Nin/Slain1/Arl3/Sarm1/Stard9/Dync2li1/Lrrc49/Tcp11l1/Dnah1/Mapre2/Shroom1/Tppp/Kif16b/Rmdn2/Kif5a	37
GO:0005891	voltage-gated calcium channel complex	CC	0.186	0.00104	0.00534	2.27	0.00353	Cacna1c/Cachd1/Cacna2d1/Cacna1e/Cacng7/Cacna1h/Cacna1a/Cacnb4	8
GO:0001518	voltage-gated sodium channel complex	CC	0.294	0.00107	0.00545	2.26	0.00361	Scn4b/Scn1a/Scn2a/Cacna1h/Scn3a	5
GO:0016327	apicolateral plasma membrane	CC	0.24	0.0011	0.00555	2.26	0.00367	Mpdz/Cdh2/Cldn8/Prickle2/Cldn5/Palm	6
GO:0005802	trans-Golgi network	CC	0.0976	0.00114	0.0057	2.24	0.00377	Car4/Nsg2/Chst2/Tgfbi/Bok/Gga2/Lrrk2/Slc9a7/Ap1m1/Prkd1/Postn/Plpp3/Mme/Chst1/Cracr2a/Dennd5a/5730455P16Rik/Pcsk5/Ms4a7/Nsg1/Ece2/Vps53/Golph3l/Atp8b4	24
GO:0008328	ionotropic glutamate receptor complex	CC	0.182	0.00122	0.00602	2.22	0.00398	Gria4/Grik1/Grin2b/Grik2/Cacng7/Cpt1c/Dlg4/Nrn1	8
GO:0043083	synaptic cleft	CC	0.278	0.00143	0.00692	2.16	0.00458	Lama4/Grin2b/Lama2/Apoe/Prss12	5
GO:0005583	fibrillar collagen trimer	CC	0.364	0.00145	0.00692	2.16	0.00458	Col11a1/Col16a1/Col5a2/Lum	4
GO:0098643	banded collagen fibril	CC	0.364	0.00145	0.00692	2.16	0.00458	Col11a1/Col16a1/Col5a2/Lum	4
GO:0030667	secretory granule membrane	CC	0.133	0.0015	0.00708	2.15	0.00468	Car4/Slc2a3/Cpe/Msn/Kif1a/Cd38/Pla1a/Ccdc136/Rab27a/Sri/Cav1/Tmem184a	12
GO:0097014	ciliary plasm	CC	0.113	0.00158	0.0074	2.13	0.00489	Gli1/Arl6/Dzip1l/Wdr35/Bbs7/Dnah5/Gli3/Ift57/Rp1/Tubb4a/Dync2h1/Arl3/Dnah7b/Dync2li1/Dnah1/Bbs1	16
GO:0098878	neurotransmitter receptor complex	CC	0.174	0.00165	0.00759	2.12	0.00502	Gria4/Grik1/Grin2b/Grik2/Cacng7/Cpt1c/Dlg4/Nrn1	8
GO:0030016	myofibril	CC	0.0982	0.00165	0.00759	2.12	0.00502	Cacna1c/Ryr1/Adra1a/Slc8a1/Pygm/Tmod2/Scn1a/Mmp2/Mef2c/Grin2b/Arhgef25/Ank2/Palld/Bin1/Myl3/Cmya5/Ryr3/Habp4/Atp2b4/Simc1/Psen1/Sri	22
GO:0060170	ciliary membrane	CC	0.158	0.00175	0.00796	2.1	0.00526	Evc2/Evc/Adcy3/Shank2/Bbs7/Tmem231/Pkd2/Bbs1/Iqce	9
GO:0032391	photoreceptor connecting cilium	CC	0.17	0.0019	0.00859	2.07	0.00568	D630045J12Rik/Tmem237/Ift57/Rp1/Cfap410/Arl3/Nphp1/Iqcb1	8
GO:0005902	microvillus	CC	0.124	0.00193	0.00866	2.06	0.00572	Angpt1/Cd44/Lrrk2/Jam3/Tek/Podxl/Msn/Nfasc/Lyz2/Myo1f/Lyz1/Spn/Atp6v1b2	13
GO:0048787	presynaptic active zone membrane	CC	0.214	0.00207	0.00913	2.04	0.00604	Stx1b/Cdh2/Kcnma1/Cacna1h/Stx2/Ntng1	6
GO:0042613	MHC class II protein complex	CC	0.333	0.0021	0.00917	2.04	0.00606	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0005884	actin filament	CC	0.113	0.00232	0.0101	2	0.00665	Hcls1/Aif1l/Myo5a/Jam3/Tek/Sh2b2/Abi2/Coro1a/Palld/Dlc1/Myo1f/Fyn/Wipf1/Dpysl3/Pstpip1	15
GO:0032589	neuron projection membrane	CC	0.139	0.00267	0.0115	1.94	0.00758	Epb41l3/Thy1/Gabra4/Kcnc4/Mpp2/Palm/Gabbr1/Itga8/Nradd/Kcnh1	10
GO:0031985	Golgi cisterna	CC	0.148	0.00282	0.012	1.92	0.00791	B4galnt4/Nsg2/Rab34/Ggta1/Lyz2/Pcsk5/Lyz1/Xylt1/Golph3l	9
GO:0000137	Golgi cis cisterna	CC	0.308	0.00291	0.0122	1.91	0.00809	Nsg2/Lyz2/Lyz1/Xylt1	4
GO:0019867	outer membrane	CC	0.0957	0.00353	0.0145	1.84	0.00962	Acsl6/Maob/Bok/Lrrk2/Maoa/Slc8a3/Armcx1/Armcx6/Aifm2/Snn/Agtr1a/Syne3/Sarm1/Cpt1c/Armcx2/Acsl1/Gimap3/Asl/Psen1/Qtrt2	20
GO:0031968	organelle outer membrane	CC	0.0957	0.00353	0.0145	1.84	0.00962	Acsl6/Maob/Bok/Lrrk2/Maoa/Slc8a3/Armcx1/Armcx6/Aifm2/Snn/Agtr1a/Syne3/Sarm1/Cpt1c/Armcx2/Acsl1/Gimap3/Asl/Psen1/Qtrt2	20
GO:0031045	dense core granule	CC	0.194	0.00357	0.0145	1.84	0.00962	Cpe/Kif1a/Cadps/Dmxl2/Syt7/Ncs1	6
GO:0016529	sarcoplasmic reticulum	CC	0.132	0.00398	0.0161	1.79	0.0106	Car4/Sgcd/Ryr1/Pygm/Cacna2d1/Cmya5/Asph/Ryr3/Gstm7/Sri	10
GO:0044291	cell-cell contact zone	CC	0.122	0.00461	0.0185	1.73	0.0122	Slc8a1/Scn4b/Cdh2/Scn1a/Jam3/Ank2/Scn2a/Pecam1/Tln2/Atp1a2/Jam2	11
GO:0044295	axonal growth cone	CC	0.159	0.00531	0.021	1.68	0.0139	Dcc/Mapk8ip1/Myo9a/Lrp2/Nin/Neo1/Ptch1	7
GO:0031526	brush border membrane	CC	0.125	0.00576	0.0224	1.65	0.0148	Car4/Abcg2/Enpep/Shank2/Lrp2/Pth1r/Ptger3/Abcb1a/Abcg3/Pld2	10
GO:0005769	early endosome	CC	0.0826	0.00622	0.0241	1.62	0.0159	Nsg2/Kdr/St8sia2/Nrp1/Bok/Myo5a/Rps6kc1/Rab34/Coro1a/Cd1d1/Mme/Epha3/H2-Ab1/Sorcs2/Apoe/Havcr2/Dysf/Nsg1/Cacng7/Zfyve9/Mvb12b/Psen1/Kif16b/Fgd2/F2r/Kcnh1/Tmem184a	27
GO:0005788	endoplasmic reticulum lumen	CC	0.119	0.0081	0.0302	1.52	0.02	Wnt6/Selenom/Eogt/Lyz2/Pcsk5/Poglut2/Tor4a/Lyz1/Cd4/Bche	10
GO:0031225	anchored component of membrane	CC	0.0939	0.00814	0.0302	1.52	0.02	Gpc6/Cntn3/Car4/Cd109/Sema7a/Gpc3/Ntm/Cdh13/Thy1/Mmp19/Rtn4rl1/Mpp2/Nrn1/Ntng1/Gpc2/Lsamp/Cd52	17
GO:0031527	filopodium membrane	CC	0.235	0.00828	0.0305	1.52	0.0202	Gap43/Msn/Palm/Tbc1d10c	4
GO:0046658	anchored component of plasma membrane	CC	0.125	0.00858	0.0314	1.5	0.0208	Gpc6/Car4/Gpc3/Thy1/Rtn4rl1/Mpp2/Nrn1/Ntng1/Gpc2	9
GO:0032587	ruffle membrane	CC	0.123	0.00937	0.0341	1.47	0.0225	Ptprz1/Map2/Aif1l/Jcad/Eps8l1/Dlc1/Fgr/Plekho1/Plek	9
GO:0005814	centriole	CC	0.102	0.00981	0.0354	1.45	0.0234	Ccdc88a/Dzip1l/Cibar1/Cep170/Cntln/Armc9/Crocc/Nin/Cep19/Ttbk2/Dzip1/Stard9/Cep97	13
GO:0032809	neuronal cell body membrane	CC	0.158	0.01	0.0358	1.45	0.0237	Kcnb2/Slc6a2/Kcnd2/Thy1/Kcnc4/Slc4a8	6
GO:0098690	glycinergic synapse	CC	0.3	0.011	0.0376	1.42	0.0249	Glrb/Iqsec3/Nlgn2	3
GO:0099569	presynaptic cytoskeleton	CC	0.3	0.011	0.0376	1.42	0.0249	Rims3/Septin3/Erc2	3
GO:1990454	L-type voltage-gated calcium channel complex	CC	0.3	0.011	0.0376	1.42	0.0249	Cacna1c/Cacna2d1/Cacng7	3
GO:0005741	mitochondrial outer membrane	CC	0.0904	0.0116	0.0396	1.4	0.0262	Acsl6/Maob/Bok/Lrrk2/Maoa/Slc8a3/Armcx1/Armcx6/Aifm2/Snn/Sarm1/Cpt1c/Armcx2/Acsl1/Gimap3/Asl/Qtrt2	17
GO:0005903	brush border	CC	0.0966	0.0123	0.0416	1.38	0.0275	Car4/Dab1/Abcg2/Enpep/Shank2/Lrp2/Pth1r/Mme/Scart1/Scin/Ptger3/Abcb1a/Abcg3/Pld2	14
GO:0032281	AMPA glutamate receptor complex	CC	0.172	0.0126	0.042	1.38	0.0278	Gria4/Cacng7/Cpt1c/Dlg4/Nrn1	5
GO:0097440	apical dendrite	CC	0.172	0.0126	0.042	1.38	0.0278	Map2/Grin2b/Osbp2/Enpp1/Kif5a	5
GO:0005871	kinesin complex	CC	0.135	0.0132	0.0437	1.36	0.0289	Kif7/Kif26a/Kif1a/Kif6/Stard9/Kif16b/Kif5a	7
GO:0001931	uropod	CC	0.273	0.0145	0.0474	1.32	0.0314	Pip5k1b/Msn/Spn	3
GO:0016010	dystrophin-associated glycoprotein complex	CC	0.2	0.015	0.0486	1.31	0.0321	Sgcd/Sntb1/Sgcb/Sspn	4
GO:0050839	cell adhesion molecule binding	MF	0.195	2.13e-20	2.03e-17	16.7	1.56e-17	Prtg/Ptprz1/Itga4/Lrrc4c/Kdr/Ptprd/Igf1/Nlgn1/Npnt/Nos3/Ptpro/Fermt2/Sema7a/Col16a1/Tgfbi/Fxyd5/Cdh2/Itgb7/Fn1/Cdh6/Tenm3/Icam1/Grin2b/Jam3/Cdh13/Cxcl12/Adgrl1/Cdh10/Itga1/Ptprm/Cdh5/Thy1/Postn/Plpp3/Cpe/Msn/Cd1d1/Cd226/Itgal/Esam/Nlgn3/Emilin1/Nfasc/Cdh11/Cd200/Igf2/Itga7/Neo1/Tln2/Dchs1/Ccn2/Psen1/Ptn/Ntng1/Itga8/Itgb4/S1pr3/Nlgn2/Jam2/Fbln5	60
GO:0046873	metal ion transmembrane transporter activity	MF	0.138	1.05e-12	3.33e-10	9.48	2.56e-10	Kcnk3/Kcnb2/Nalcn/Slc1a3/Kcnj3/Cacna1c/Grik1/Kcna6/Slc6a2/Kcnd2/Slc5a11/Slc13a5/Ryr1/Kcnd3/Slc12a8/Slc8a1/Scn4b/Cachd1/Scn1a/Cacna2d1/Kcnq5/Slc9a7/Slc24a4/Rasa3/Grin2b/Slc24a3/Cacna1e/Slc8a3/Trpc6/Htr1b/Nalf1/Slc6a15/Scn2a/Grik2/Kcnma1/Slc9a5/Slc23a2/Kcnc4/Pkd1/Cacng7/Kcnip3/Ncs1/Slc12a4/Slc38a1/Pkd2/Ryr3/Cacna1h/Kcng4/Atp2b4/Scn3a/Atp1a2/Slc4a8/Psen1/Pkdrej/Kcnq4/Cacna1a/Cacnb4/Kcnh1	58
GO:0030695	GTPase regulator activity	MF	0.135	3.73e-12	7.1e-10	9.15	5.46e-10	Wnt11/Agap2/Ccdc88a/Nrp1/Rgs6/Rgs16/Rasgrp3/Garnl3/Lrrk2/Arhgap45/Rasa3/Arhgef25/Tbc1d24/Arhgap25/Plcb1/Dock2/Rasgrp2/Myo9a/Denn2b/Syde1/Thy1/Dock10/Sh3bp1/Arhgap6/Eps8l1/Arhgef40/Rgs5/Arhgef15/Dennd5a/Nckap1l/Arap3/Arrb1/Prex2/Arhgap10/Dlc1/Arhgap28/Net1/Fgd1/Gnb5/Arhgap31/Syngap1/Arfgap3/Ngef/Arhgef9/Fgd5/Arhgap15/Dennd4a/Sh2d3c/Iqsec3/Gpsm1/Fgd2/Sipa1/Tbc1d10c/Rasal3/Rabep1/Acap1/Plekhg5	57
GO:0060589	nucleoside-triphosphatase regulator activity	MF	0.135	3.73e-12	7.1e-10	9.15	5.46e-10	Wnt11/Agap2/Ccdc88a/Nrp1/Rgs6/Rgs16/Rasgrp3/Garnl3/Lrrk2/Arhgap45/Rasa3/Arhgef25/Tbc1d24/Arhgap25/Plcb1/Dock2/Rasgrp2/Myo9a/Denn2b/Syde1/Thy1/Dock10/Sh3bp1/Arhgap6/Eps8l1/Arhgef40/Rgs5/Arhgef15/Dennd5a/Nckap1l/Arap3/Arrb1/Prex2/Arhgap10/Dlc1/Arhgap28/Net1/Fgd1/Gnb5/Arhgap31/Syngap1/Arfgap3/Ngef/Arhgef9/Fgd5/Arhgap15/Dennd4a/Sh2d3c/Iqsec3/Gpsm1/Fgd2/Sipa1/Tbc1d10c/Rasal3/Rabep1/Acap1/Plekhg5	57
GO:0005539	glycosaminoglycan binding	MF	0.167	1.53e-11	2.43e-09	8.61	1.87e-09	Apob/Col11a1/Vit/Sema5a/Mdk/Thbs3/Nrp1/Cd44/Spock2/Fn1/Serpine2/Egflam/Adamts1/Col13a1/Mamdc2/Postn/Nell1/Smoc1/Apoe/Layn/Ndnf/Tnfaip6/Bgn/Rtn4rl1/Hapln3/Ptch1/Abi3bp/Habp4/Ccn2/Efemp2/Dpysl3/Fstl1/Ptn/Stab1/Bmp7/Vcan/Slit3/Ccdc80/Eng	39
GO:0005261	cation channel activity	MF	0.144	1.89e-11	2.57e-09	8.59	1.97e-09	Kcnk3/Kcnb2/Nalcn/Kcnj3/Gria4/Cacna1c/Grik1/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Cachd1/Scn1a/Cacna2d1/Kcnq5/Slc24a4/Ano1/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpm3/Unc80/Trpc6/Htr1b/Nalf1/Scn2a/Grik2/Kcnma1/Kcnc4/Pkd1/Cacng7/Kcnip3/Ncs1/Pkd2/Ryr3/Cacna1h/Kcng4/Scn3a/Psen1/Piezo2/Pkdrej/Kcnq4/Cacna1a/Cacnb4/Kcnh1	48
GO:0005216	ion channel activity	MF	0.128	5.11e-11	6.08e-09	8.22	4.68e-09	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Gria4/Cacna1c/Grik1/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Cachd1/Scn1a/Cacna2d1/Kcnq5/Slc24a4/Ano1/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpm3/Ano2/Unc80/Ttyh2/Trpc6/Htr1b/Nalf1/Glrb/Scn2a/Gabra4/Grik2/Kcnma1/Gjc1/Kcnc4/Pkd1/Cacng7/Kcnip3/Ncs1/Pkd2/Ryr3/Cacna1h/Kcng4/Scn3a/Clca2/Psen1/Piezo2/Pkdrej/Kcnq4/Cacna1a/Lrrc8c/Cacnb4/Kcnh1	56
GO:0022836	gated channel activity	MF	0.142	7.49e-11	7.85e-09	8.1	6.04e-09	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Gria4/Cacna1c/Grik1/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Cachd1/Scn1a/Cacna2d1/Kcnq5/Ano1/Rasa3/Grin2b/Cacna1e/Ano2/Ttyh2/Htr1b/Nalf1/Glrb/Scn2a/Gabra4/Grik2/Kcnma1/Kcnc4/Cacng7/Kcnip3/Ncs1/Pkd2/Ryr3/Cacna1h/Kcng4/Scn3a/Clca2/Piezo2/Kcnq4/Cacna1a/Cacnb4/Kcnh1	46
GO:0005178	integrin binding	MF	0.194	8.67e-11	7.85e-09	8.1	6.04e-09	Ptprz1/Itga4/Kdr/Igf1/Npnt/Fermt2/Sema7a/Col16a1/Tgfbi/Itgb7/Fn1/Icam1/Jam3/Cxcl12/Itga1/Thy1/Plpp3/Cd226/Itgal/Emilin1/Igf2/Itga7/Tln2/Ccn2/Ptn/Itga8/Itgb4/S1pr3/Jam2/Fbln5	30
GO:0005096	GTPase activator activity	MF	0.161	9.08e-11	7.85e-09	8.1	6.04e-09	Wnt11/Agap2/Nrp1/Rgs6/Rgs16/Rasgrp3/Garnl3/Lrrk2/Arhgap45/Rasa3/Tbc1d24/Arhgap25/Plcb1/Dock2/Myo9a/Syde1/Thy1/Sh3bp1/Arhgap6/Rgs5/Arhgef15/Nckap1l/Arap3/Arrb1/Prex2/Arhgap10/Dlc1/Arhgap28/Gnb5/Arhgap31/Syngap1/Arfgap3/Arhgap15/Sipa1/Tbc1d10c/Rasal3/Rabep1/Acap1	38
GO:0015267	channel activity	MF	0.12	2.56e-10	1.88e-08	7.73	1.44e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Gria4/Cacna1c/Grik1/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Cachd1/Scn1a/Cacna2d1/Kcnq5/Slc24a4/Ano1/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpm3/Ano2/Unc80/Ttyh2/Trpc6/Htr1b/Nalf1/Glrb/Scn2a/Gja4/Gabra4/Grik2/Kcnma1/Gjc1/Kcnc4/Pkd1/Cacng7/Kcnip3/Ncs1/Pkd2/Ryr3/Cacna1h/Aqp11/Kcng4/Scn3a/Clca2/Psen1/Piezo2/Pkdrej/Kcnq4/Cacna1a/Lrrc8c/Cacnb4/Kcnh1	58
GO:0022803	passive transmembrane transporter activity	MF	0.12	2.56e-10	1.88e-08	7.73	1.44e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Gria4/Cacna1c/Grik1/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Cachd1/Scn1a/Cacna2d1/Kcnq5/Slc24a4/Ano1/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpm3/Ano2/Unc80/Ttyh2/Trpc6/Htr1b/Nalf1/Glrb/Scn2a/Gja4/Gabra4/Grik2/Kcnma1/Gjc1/Kcnc4/Pkd1/Cacng7/Kcnip3/Ncs1/Pkd2/Ryr3/Cacna1h/Aqp11/Kcng4/Scn3a/Clca2/Psen1/Piezo2/Pkdrej/Kcnq4/Cacna1a/Lrrc8c/Cacnb4/Kcnh1	58
GO:0005244	voltage-gated ion channel activity	MF	0.167	1.12e-09	7.12e-08	7.15	5.48e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Cacna1c/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/Cachd1/Scn1a/Cacna2d1/Kcnq5/Ano1/Grin2b/Cacna1e/Htr1b/Scn2a/Kcnma1/Kcnc4/Cacng7/Kcnip3/Ncs1/Pkd2/Cacna1h/Kcng4/Scn3a/Kcnq4/Cacna1a/Cacnb4/Kcnh1	32
GO:0005516	calmodulin binding	MF	0.167	1.12e-09	7.12e-08	7.15	5.48e-08	Gap43/Map2/Cacna1c/Ryr1/Slc8a1/Nos3/Kcnq5/Myo5a/Slc24a4/Pde1b/Adcy3/Akap12/Plcb1/Slc8a3/Sntb1/Cth/Nrgn/Pde1a/Syt7/Cnn2/Myo1f/Cnn3/Ryr3/Rrad/Iqcb1/Atp2b4/Scn3a/Kcnq4/Cacna1a/Mknk2/Kcnh1/Camk1	32
GO:0022832	voltage-gated channel activity	MF	0.166	1.28e-09	7.64e-08	7.12	5.88e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Cacna1c/Kcna6/Kcnd2/Ryr1/Kcnd3/Scn4b/Cachd1/Scn1a/Cacna2d1/Kcnq5/Ano1/Grin2b/Cacna1e/Htr1b/Scn2a/Kcnma1/Kcnc4/Cacng7/Kcnip3/Ncs1/Pkd2/Cacna1h/Kcng4/Scn3a/Kcnq4/Cacna1a/Cacnb4/Kcnh1	32
GO:0003779	actin binding	MF	0.117	5.49e-09	3.07e-07	6.51	2.37e-07	Lsp1/Myo16/Map2/Slc6a2/Evl/Epb41l3/Nos3/Ccdc88a/Hcls1/Fermt2/Aif1l/Fxyd5/Tmod2/Wasf3/Lrrk2/Myo5a/Pfn2/Mical1/Vash1/Myo9a/Trpc6/Msn/Coro1a/Sntb1/Palld/Limch1/Eps8l1/Cnn2/Kcnma1/Crocc/Daam2/Hip1/Scin/Parvg/Bin1/Myl3/Cap2/Parvb/Rai14/Flnc/Syne3/Tln2/Myo1f/Cnn3/Wipf1/Pknox2/Plekhh2/Actr3b/Shroom1/Vash2/Fmnl3/Pstpip1	52
GO:0015085	calcium ion transmembrane transporter activity	MF	0.187	6.94e-09	3.67e-07	6.44	2.83e-07	Cacna1c/Ryr1/Slc8a1/Cachd1/Cacna2d1/Slc24a4/Rasa3/Grin2b/Slc24a3/Cacna1e/Slc8a3/Trpc6/Htr1b/Nalf1/Pkd1/Cacng7/Ncs1/Pkd2/Ryr3/Cacna1h/Atp2b4/Psen1/Pkdrej/Cacna1a/Cacnb4	25
GO:0022843	voltage-gated cation channel activity	MF	0.176	2.35e-08	1.18e-06	5.93	9.05e-07	Kcnk3/Kcnb2/Kcnj3/Cacna1c/Kcna6/Kcnd2/Ryr1/Kcnd3/Cachd1/Cacna2d1/Kcnq5/Grin2b/Cacna1e/Htr1b/Kcnma1/Kcnc4/Cacng7/Ncs1/Pkd2/Cacna1h/Kcng4/Kcnq4/Cacna1a/Cacnb4/Kcnh1	25
GO:0005262	calcium channel activity	MF	0.19	4.03e-08	1.92e-06	5.72	1.48e-06	Cacna1c/Ryr1/Cachd1/Cacna2d1/Slc24a4/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpc6/Htr1b/Nalf1/Pkd1/Cacng7/Ncs1/Pkd2/Ryr3/Cacna1h/Psen1/Pkdrej/Cacna1a/Cacnb4	22
GO:0015081	sodium ion transmembrane transporter activity	MF	0.166	1.5e-07	6.78e-06	5.17	5.22e-06	Nalcn/Slc1a3/Grik1/Slc6a2/Slc5a11/Slc13a5/Slc8a1/Scn4b/Scn1a/Slc9a7/Slc24a4/Slc24a3/Slc8a3/Slc6a15/Scn2a/Grik2/Slc9a5/Slc23a2/Slc38a1/Pkd2/Cacna1h/Scn3a/Atp1a2/Slc4a8	24
GO:0016757	glycosyltransferase activity	MF	0.127	3.69e-07	1.53e-05	4.82	1.18e-05	B4galnt4/St6gal2/St8sia2/St8sia4/Gxylt2/Uggt2/Pygm/Tmtc1/B4galt2/B3galnt1/Fut10/Has2/Galnt16/St3gal2/Lfng/St6galnac4/Eogt/Ggta1/Lacc1/St8sia6/Galntl6/Poglut2/Mgat3/Pomt2/Large1/St6galnac6/B3gnt5/Xylt1/St3gal4/Mfng/Qtrt2/Pygl/Galnt18/Dpy19l1	34
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MF	0.117	4.02e-07	1.59e-05	4.8	1.23e-05	Lef1/Zeb2/Tbx2/Prdm5/Zfp37/Hoxd9/Osr2/Klf8/Zfp239/Tcf21/Glis1/Bcl6b/Zeb1/Prdm1/Zfp13/Zfp248/Tbx3/Heyl/Irf8/Zbtb46/Snai1/Satb1/Peg3/Zfp382/Klf12/Foxs1/Nfatc4/Zbtb20/Kcnip3/Zbtb8a/Nr2f1/Zfp512b/Cux2/Ets2/Zfp566/Zfp90/Zfp763/Hey2/Myc	39
GO:0001217	DNA-binding transcription repressor activity	MF	0.116	5.06e-07	1.93e-05	4.72	1.48e-05	Lef1/Zeb2/Tbx2/Prdm5/Zfp37/Hoxd9/Osr2/Klf8/Zfp239/Tcf21/Glis1/Bcl6b/Zeb1/Prdm1/Zfp13/Zfp248/Tbx3/Heyl/Irf8/Zbtb46/Snai1/Satb1/Peg3/Zfp382/Klf12/Foxs1/Nfatc4/Zbtb20/Kcnip3/Zbtb8a/Nr2f1/Zfp512b/Cux2/Ets2/Zfp566/Zfp90/Zfp763/Hey2/Myc	39
GO:0035591	signaling adaptor activity	MF	0.214	1.13e-06	4.13e-05	4.38	3.18e-05	Lrrk2/Shank2/Mapk8ip1/Akap12/Sh2b2/Abi2/Magi2/Sarm1/Afap1l2/Gnb5/Gnb4/Lat/Sh2d3c/Grb10/Irs1	15
GO:0008237	metallopeptidase activity	MF	0.141	1.24e-06	4.2e-05	4.38	3.23e-05	Cpxm2/Mmp16/Adamts20/Adamts16/Adamts19/Mmp2/Enpep/Adam33/Adamts1/Vash1/Naalad2/Cpe/Adamts10/Mme/Adamts7/Adam11/Agbl3/Mmp19/Trhde/Ece2/Adam19/Clca2/Pappa/Adamts17/Vash2/Lvrn	26
GO:0030020	extracellular matrix structural constituent conferring tensile strength	MF	0.289	1.28e-06	4.2e-05	4.38	3.23e-05	Col11a1/Col14a1/Col4a6/Col16a1/Col9a2/Col13a1/Col5a2/Col15a1/Col23a1/Col18a1/Col4a5	11
GO:0030159	signaling receptor complex adaptor activity	MF	0.289	1.28e-06	4.2e-05	4.38	3.23e-05	Lrrk2/Shank2/Akap12/Sh2b2/Magi2/Gnb5/Gnb4/Lat/Sh2d3c/Grb10/Irs1	11
GO:0019838	growth factor binding	MF	0.15	1.55e-06	4.9e-05	4.31	3.77e-05	Epha8/Ptprz1/Cd109/Kdr/Nrp1/Il11ra1/Tek/Lrp2/Flt3/Epha3/Tsku/Ltbp3/Epha7/Nrros/Ccn2/Pdgfrb/Ptn/Il2rg/Igfbp4/Itgb4/Nkd2/Nradd/Eng	23
GO:0005245	voltage-gated calcium channel activity	MF	0.255	1.86e-06	5.67e-05	4.25	4.37e-05	Cacna1c/Ryr1/Cachd1/Cacna2d1/Cacna1e/Htr1b/Cacng7/Ncs1/Pkd2/Cacna1h/Cacna1a/Cacnb4	12
GO:0017124	SH3 domain binding	MF	0.158	1.94e-06	5.67e-05	4.25	4.37e-05	Evl/Hcls1/Drd4/Abi3/Mical1/Shank2/Lrp2/Abi2/Sh3bp1/Arhgap6/Afap1l1/Prrt2/Efs/Wipf1/Afap1l2/Adam19/Arhgap31/Dpysl3/Syngap1/Elmo2/Pdcd6ip	21
GO:0005080	protein kinase C binding	MF	0.219	1.97e-06	5.67e-05	4.25	4.37e-05	Fez1/Ccdc88a/Nell1/Adcy4/Pard6g/Hdac9/Cavin3/BC034090/Cavin2/Akt3/Pld2/Dact1/Plek/Irs1	14
GO:0015079	potassium ion transmembrane transporter activity	MF	0.146	2.43e-06	6.81e-05	4.17	5.24e-05	Kcnk3/Kcnb2/Kcnj3/Grik1/Kcna6/Kcnd2/Kcnd3/Slc12a8/Kcnq5/Slc9a7/Slc24a4/Slc24a3/Grik2/Kcnma1/Slc9a5/Kcnc4/Kcnip3/Slc12a4/Pkd2/Kcng4/Atp1a2/Kcnq4/Kcnh1	23
GO:0008201	heparin binding	MF	0.141	2.89e-06	7.85e-05	4.1	6.04e-05	Apob/Col11a1/Mdk/Thbs3/Nrp1/Fn1/Serpine2/Adamts1/Col13a1/Postn/Nell1/Smoc1/Apoe/Ndnf/Rtn4rl1/Ptch1/Abi3bp/Ccn2/Efemp2/Fstl1/Ptn/Bmp7/Slit3/Ccdc80	24
GO:0008373	sialyltransferase activity	MF	0.381	3.63e-06	9.6e-05	4.02	7.39e-05	St6gal2/St8sia2/St8sia4/St3gal2/St6galnac4/St8sia6/St6galnac6/St3gal4	8
GO:0004713	protein tyrosine kinase activity	MF	0.156	3.99e-06	0.000103	3.99	7.9e-05	Epha8/Kdr/Ddr2/Pkdcc/Nrp1/Itk/Tek/Flt3/Kit/Epha3/Tie1/Hipk2/Epha7/Fyn/Fgr/Zap70/Styk1/Pdgfrb/Hipk1/Ror1	20
GO:0045296	cadherin binding	MF	0.203	5.06e-06	0.000127	3.9	9.75e-05	Kdr/Nos3/Ptpro/Fxyd5/Cdh2/Cdh6/Cdh13/Cdh10/Ptprm/Cdh5/Cdh11/Neo1/Dchs1/Psen1	14
GO:0004714	transmembrane receptor protein tyrosine kinase activity	MF	0.207	1.93e-05	0.00047	3.33	0.000362	Epha8/Kdr/Ddr2/Nrp1/Tek/Flt3/Kit/Epha3/Tie1/Epha7/Pdgfrb/Ror1	12
GO:0044325	transmembrane transporter binding	MF	0.136	3.26e-05	0.000775	3.11	0.000597	Kcnb2/Cacna1c/Kcnd3/Tcaf1/Slc8a1/Rims3/Scn4b/Lrrk2/Ank2/Cdh5/Pkd1/Arrb1/Kcnip3/Mpp2/Pkd2/Fhl1/Fyn/Kcng4/Cav1/Kcnh1	20
GO:0001664	G protein-coupled receptor binding	MF	0.103	4.59e-05	0.00106	2.97	0.000819	Cxcl15/Ndp/Wnt6/Wnt11/Ptch2/Gprasp2/Tub/Gnai1/Ednrb/Grin2b/Cxcl12/Cnrip1/Edn3/Calca/Wnt9a/Znrf3/Reep1/Agtr1a/Magi2/Bdkrb2/Xcl1/Arrb1/Arrb2/Ptch1/Fyn/Gnaz/Dlg4/Palm/Apln/Bbs1/Nes/Itgb4/Pdcd6ip	33
GO:0004222	metalloendopeptidase activity	MF	0.151	5.52e-05	0.00125	2.9	0.000961	Mmp16/Adamts20/Adamts16/Adamts19/Mmp2/Adam33/Adamts1/Adamts10/Mme/Adamts7/Adam11/Mmp19/Ece2/Adam19/Pappa/Adamts17	16
GO:0098879	structural constituent of postsynaptic specialization	MF	0.5	5.64e-05	0.00125	2.9	0.000961	Shank2/Dlg2/Magi2/Mpp2/Dlg4	5
GO:0008509	anion transmembrane transporter activity	MF	0.102	7e-05	0.00151	2.82	0.00117	Slc1a3/Grik1/Slc6a2/Slc13a5/Slc2a3/Slc12a8/Slc9a7/Slc24a4/Ano1/Slc7a2/Abcg2/Slc36a4/Slc24a3/Ano2/Ttyh2/Glrb/Slc29a1/Gabra4/Slc9a5/Slc23a2/Sfxn5/Slc12a4/Slc38a1/Slco4c1/Slc4a3/Slc25a23/Clca2/Slc4a8/Abcc5/Abcg3/Lrrc8c/Ank	32
GO:0019199	transmembrane receptor protein kinase activity	MF	0.171	7.29e-05	0.00154	2.81	0.00119	Epha8/Kdr/Ddr2/Nrp1/Tek/Flt3/Kit/Epha3/Tie1/Epha7/Pdgfrb/Ror1/Eng	13
GO:0005540	hyaluronic acid binding	MF	0.292	0.000108	0.00219	2.66	0.00168	Cd44/Layn/Tnfaip6/Hapln3/Habp4/Stab1/Vcan	7
GO:0005248	voltage-gated sodium channel activity	MF	0.28	0.000144	0.00279	2.55	0.00215	Nalcn/Scn4b/Scn1a/Scn2a/Pkd2/Cacna1h/Scn3a	7
GO:0016849	phosphorus-oxygen lyase activity	MF	0.28	0.000144	0.00279	2.55	0.00215	Gucy1a2/Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7/Cd38	7
GO:0004016	adenylate cyclase activity	MF	0.417	0.000163	0.00311	2.51	0.00239	Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7	5
GO:0005525	GTP binding	MF	0.0947	0.000188	0.00351	2.45	0.0027	Rragb/Agap2/Rasl12/Rab36/Gimap4/Arl6/Gnai1/Lrrk2/Gucy1b1/Gimap8/Dnajc27/Rab34/Rragd/Gucy1a1/Gimap6/Cracr2a/Tubb4a/Rhobtb3/Nin/Arl3/Septin3/Rasd2/Rrad/Gnaz/Rab23/Septin4/Gimap5/Gimap3/Rab39b/Rab27a/Septin6/Suclg2/Rap2a/Rab20	34
GO:0003774	cytoskeletal motor activity	MF	0.142	0.000196	0.00357	2.45	0.00275	Myo16/Kif7/Myo5a/Dnah5/Myo9a/Kif1a/Dync2h1/Kif6/Myl3/Myo1f/Dnah7b/Stard9/Dnah1/Kif16b/Kif5a	15
GO:0016758	hexosyltransferase activity	MF	0.114	0.000199	0.00357	2.45	0.00275	B4galnt4/Uggt2/Pygm/Tmtc1/B4galt2/B3galnt1/Fut10/Has2/Galnt16/Lfng/Eogt/Ggta1/Galntl6/Poglut2/Mgat3/Pomt2/Large1/B3gnt5/Mfng/Pygl/Galnt18/Dpy19l1	22
GO:0005272	sodium channel activity	MF	0.205	0.000231	0.00389	2.41	0.00299	Nalcn/Grik1/Scn4b/Scn1a/Scn2a/Grik2/Pkd2/Cacna1h/Scn3a	9
GO:0023026	MHC class II protein complex binding	MF	0.385	0.000255	0.00404	2.39	0.00311	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa/Cd4	5
GO:0099511	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	MF	0.385	0.000255	0.00404	2.39	0.00311	Cacna1e/Htr1b/Ncs1/Cacna1a/Cacnb4	5
GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	MF	0.385	0.000255	0.00404	2.39	0.00311	Cacna1e/Htr1b/Ncs1/Cacna1a/Cacnb4	5
GO:0005267	potassium channel activity	MF	0.132	0.00027	0.00422	2.38	0.00324	Kcnk3/Kcnb2/Kcnj3/Grik1/Kcna6/Kcnd2/Kcnd3/Kcnq5/Grik2/Kcnma1/Kcnc4/Kcnip3/Pkd2/Kcng4/Kcnq4/Kcnh1	16
GO:0019001	guanyl nucleotide binding	MF	0.0916	0.000287	0.00433	2.36	0.00333	Rragb/Agap2/Rasl12/Rab36/Gimap4/Arl6/Gnai1/Lrrk2/Gucy1b1/Gimap8/Dnajc27/Rab34/Rragd/Gucy1a1/Gimap6/Cracr2a/Tubb4a/Rhobtb3/Nin/Arl3/Septin3/Rasd2/Pde5a/Rrad/Gnaz/Rab23/Septin4/Gimap5/Gimap3/Rab39b/Rab27a/Septin6/Suclg2/Rap2a/Rab20	35
GO:0032561	guanyl ribonucleotide binding	MF	0.0916	0.000287	0.00433	2.36	0.00333	Rragb/Agap2/Rasl12/Rab36/Gimap4/Arl6/Gnai1/Lrrk2/Gucy1b1/Gimap8/Dnajc27/Rab34/Rragd/Gucy1a1/Gimap6/Cracr2a/Tubb4a/Rhobtb3/Nin/Arl3/Septin3/Rasd2/Pde5a/Rrad/Gnaz/Rab23/Septin4/Gimap5/Gimap3/Rab39b/Rab27a/Septin6/Suclg2/Rap2a/Rab20	35
GO:0140359	ABC-type transporter activity	MF	0.25	0.000311	0.00463	2.33	0.00356	Abcg2/Abcg1/Abca8b/Abcb1a/Abcc5/Abcg3/Abcg4	7
GO:0005249	voltage-gated potassium channel activity	MF	0.148	0.000334	0.00481	2.32	0.0037	Kcnk3/Kcnb2/Kcnj3/Kcna6/Kcnd2/Kcnd3/Kcnq5/Kcnma1/Kcnc4/Pkd2/Kcng4/Kcnq4/Kcnh1	13
GO:0008194	UDP-glycosyltransferase activity	MF	0.121	0.000361	0.00512	2.29	0.00394	B4galnt4/Gxylt2/Uggt2/B4galt2/B3galnt1/Has2/Galnt16/Lfng/Eogt/Ggta1/Galntl6/Poglut2/Mgat3/Large1/B3gnt5/Xylt1/Mfng/Galnt18	18
GO:0005251	delayed rectifier potassium channel activity	MF	0.233	0.000491	0.00678	2.17	0.00522	Kcnb2/Kcna6/Kcnq5/Kcnc4/Kcng4/Kcnq4/Kcnh1	7
GO:0030215	semaphorin receptor binding	MF	0.273	0.000508	0.0069	2.16	0.00531	Sema5a/Sema5b/Sema7a/Sh3bp1/Sema3g/Sema6a	6
GO:0042043	neurexin family protein binding	MF	0.333	0.000547	0.00734	2.13	0.00565	Nlgn1/Cpe/Nlgn3/Dlg4/Nlgn2	5
GO:0005543	phospholipid binding	MF	0.085	0.000601	0.00794	2.1	0.00611	Apob/Gap43/Nme4/Pla2g10/Nr5a2/Mark1/Syt13/Ccdc88a/Cpne5/Fermt2/P2rx2/Dab1/Pfn2/Cibar1/Lpar4/Rps6kc1/Plcb1/Thy1/Pltp/Mme/Cadps/Nrgn/Apoe/Syt7/Hip1/Scin/Dysf/Bin1/Arap3/Epdr1/Pard3b/Plcb2/Zfyve9/Cavin2/Pld2/Kif16b/Golph3l/Fgd2/Kcnh1	39
GO:0003924	GTPase activity	MF	0.0952	0.000609	0.00794	2.1	0.00611	Rragb/Agap2/Rasl12/Rab36/Arl6/Gnai1/Lrrk2/Dnajc27/Rab34/Rragd/Cracr2a/Tubb4a/Rhobtb3/Gng2/Arl3/Septin3/Rasd2/Rrad/Gnaz/Rab23/Septin4/Gnb4/Rab39b/Rab27a/Tppp/Septin6/Rap2a/Rab20	28
GO:0008235	metalloexopeptidase activity	MF	0.164	0.000689	0.00887	2.05	0.00682	Cpxm2/Mmp16/Enpep/Vash1/Naalad2/Cpe/Agbl3/Trhde/Vash2/Lvrn	10
GO:0015631	tubulin binding	MF	0.0881	0.000702	0.00891	2.05	0.00686	Gli1/Map2/Fez1/Capn6/Ccdc88a/Kif7/Lrrk2/Kif26a/Ndn/Kif1a/Reep1/Eml1/Map9/Rp1/Katnal1/Kif6/Dysf/Dclk2/Nin/Arl3/Tbcel/Fyn/Cnn3/Unc5c/Stard9/Brsk1/Mapre2/Tppp/Vash2/Ift81/Kif16b/Map7d3/Rmdn2/Kif5a	34
GO:0043548	phosphatidylinositol 3-kinase binding	MF	0.195	0.000714	0.00894	2.05	0.00688	Fam83a/Dab1/Flt3/Coro1a/Rasd2/Fyn/Pdgfrb/Irs1	8
GO:0015248	sterol transporter activity	MF	0.219	0.000746	0.00922	2.04	0.0071	Apob/Osbp2/Pltp/Apoe/Abcg1/Osbpl1a/Abcg4	7
GO:0015491	cation:cation antiporter activity	MF	0.25	0.000842	0.0101	1.99	0.00781	Slc8a1/Slc9a7/Slc24a4/Slc24a3/Slc8a3/Slc9a5	6
GO:0031681	G-protein beta-subunit binding	MF	0.25	0.000842	0.0101	1.99	0.00781	Gngt2/Gng11/Gng2/Rasd2/Gng7/F2r	6
GO:0015368	calcium:cation antiporter activity	MF	0.4	0.000936	0.0109	1.96	0.0084	Slc8a1/Slc24a4/Slc24a3/Slc8a3	4
GO:0035374	chondroitin sulfate binding	MF	0.4	0.000936	0.0109	1.96	0.0084	Mdk/Rtn4rl1/Dpysl3/Ptn	4
GO:0050660	flavin adenine dinucleotide binding	MF	0.14	0.00094	0.0109	1.96	0.0084	Gulo/Maob/Nos3/Mical1/Maoa/Fmo1/Aifm2/Dpyd/Steap4/Sardh/Prodh/Aox4	12
GO:0019842	vitamin binding	MF	0.118	0.000998	0.0114	1.94	0.00881	Stra6/P3h3/Abat/P4htm/Cbs/Pygm/Rbp7/Sptlc3/Kyat1/Hdc/Dhtkd1/Cth/P3h1/Sardh/S100g/Pygl	16
GO:0003777	microtubule motor activity	MF	0.156	0.00101	0.0115	1.94	0.00885	Kif7/Dnah5/Kif1a/Dync2h1/Kif6/Dnah7b/Stard9/Dnah1/Kif16b/Kif5a	10
GO:0008559	ABC-type xenobiotic transporter activity	MF	0.294	0.00104	0.0116	1.93	0.00896	Abcg2/Abca8b/Abcb1a/Abcc5/Abcg3	5
GO:0022804	active transmembrane transporter activity	MF	0.0859	0.00109	0.0118	1.93	0.00912	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc8a1/Slc9a7/Slc24a4/Abcg2/Slc36a4/Slc24a3/Slc8a3/Slc2a13/Slc6a15/Slc9a5/Slc23a2/Atp6v0e2/Abca5/Abcg1/Slc12a4/Slc38a1/Abca8b/Slco4c1/Slc4a3/Atp2b4/Cox4i2/Abcd2/Atp1a2/Slc4a8/Abcb1a/Abcc5/Abcg3/Ank/Abcg4	34
GO:0098632	cell-cell adhesion mediator activity	MF	0.206	0.0011	0.0118	1.93	0.00912	Prtg/Lrrc4c/Jam3/Esam/Nfasc/Cd200/Ntng1	7
GO:0004181	metallocarboxypeptidase activity	MF	0.231	0.00132	0.0142	1.85	0.0109	Cpxm2/Vash1/Naalad2/Cpe/Agbl3/Vash2	6
GO:0004970	ionotropic glutamate receptor activity	MF	0.278	0.00138	0.0146	1.84	0.0112	Grid1/Gria4/Grik1/Grin2b/Grik2	5
GO:0008331	high voltage-gated calcium channel activity	MF	0.364	0.00141	0.0146	1.83	0.0113	Cacna1c/Cacna1e/Cacna1a/Cacnb4	4
GO:0042285	xylosyltransferase activity	MF	0.364	0.00141	0.0146	1.83	0.0113	Gxylt2/Poglut2/Large1/Xylt1	4
GO:0030674	protein-macromolecule adaptor activity	MF	0.089	0.00144	0.0147	1.83	0.0113	Aph1b/Epb41l3/Stx1b/Lrrk2/Ap1m1/Klhdc2/Shank2/Mapk8ip1/Akap12/Cntln/Ank2/Sh2b2/Abi2/Spsb4/Magi2/Hip1/Arrb1/Syne3/Sarm1/Frmd4a/Afap1l2/Gnb5/Stx2/Gnb4/Lat/Cav1/Sh2d3c/Grb10/Irs1	29
GO:0022853	active ion transmembrane transporter activity	MF	0.0966	0.00148	0.0149	1.83	0.0115	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc8a1/Slc9a7/Slc24a4/Slc24a3/Slc8a3/Slc2a13/Slc6a15/Slc9a5/Slc23a2/Atp6v0e2/Slc12a4/Slc38a1/Slco4c1/Slc4a3/Atp2b4/Cox4i2/Atp1a2/Slc4a8	23
GO:0042169	SH2 domain binding	MF	0.174	0.00157	0.0156	1.81	0.012	Ccdc88a/Dab1/Sh2b2/Kit/Dlc1/Afap1l2/Lax1/Irs1	8
GO:0070888	E-box binding	MF	0.174	0.00157	0.0156	1.81	0.012	Tcf21/Zeb1/Tcf4/Snai1/Tal1/Hand2/Myc/Twist1	8
GO:0019955	cytokine binding	MF	0.112	0.0017	0.0167	1.78	0.0128	Itga4/Cd109/Nog/Cd44/Il11ra1/Cxcr3/Kit/Il27ra/Tsku/Ltbp3/Nrros/Xcr1/Il12rb1/Il2rg/Cd4/Eng	16
GO:0008017	microtubule binding	MF	0.0923	0.0018	0.0175	1.76	0.0135	Gli1/Map2/Capn6/Ccdc88a/Kif7/Kif26a/Kif1a/Reep1/Eml1/Map9/Rp1/Katnal1/Kif6/Dysf/Dclk2/Nin/Arl3/Cnn3/Stard9/Mapre2/Vash2/Kif16b/Map7d3/Rmdn2/Kif5a	25
GO:0005158	insulin receptor binding	MF	0.214	0.00199	0.0192	1.72	0.0148	Igf1/Ccdc88a/Enpp1/Igf2/Grb10/Irs1	6
GO:0031402	sodium ion binding	MF	0.333	0.00204	0.0194	1.71	0.0149	Scn1a/Scn2a/Scn3a/Atp1a2	4
GO:0030165	PDZ domain binding	MF	0.117	0.00218	0.0205	1.69	0.0158	Mpp3/Nlgn1/Nkd1/Lrp2/Sntb1/Dlg2/Grik2/Lin7a/Mpp2/Erc2/Dlg4/Fzd2/Atp2b4/Psen1	14
GO:0099186	structural constituent of postsynapse	MF	0.25	0.0023	0.0215	1.67	0.0166	Shank2/Dlg2/Magi2/Mpp2/Dlg4	5
GO:0015298	solute:cation antiporter activity	MF	0.207	0.00241	0.022	1.66	0.0169	Slc8a1/Slc9a7/Slc24a4/Slc24a3/Slc8a3/Slc9a5	6
GO:0045499	chemorepellent activity	MF	0.207	0.00241	0.022	1.66	0.0169	Sema5a/Sema5b/Sema7a/Sema3g/Epha7/Sema6a	6
GO:0008083	growth factor activity	MF	0.108	0.00242	0.022	1.66	0.0169	Hgf/Mdk/Igf1/Areg/Cxcl12/Gdf11/Gdf7/Jag2/Gdf10/Vegfc/Igf2/Kitl/Ccn2/Ptn/Bmp7/Rabep1	16
GO:0008238	exopeptidase activity	MF	0.125	0.00246	0.0221	1.66	0.017	Cpxm2/Mmp16/Enpep/Vash1/Naalad2/Cpe/Mme/Agbl3/Trhde/Mindy1/Vash2/Lvrn	12
GO:0015276	ligand-gated ion channel activity	MF	0.111	0.0025	0.0222	1.65	0.0171	Kcnj3/Grid1/Gria4/Grik1/Ryr1/P2rx2/Rasa3/Grin2b/Glrb/Gabra4/Grik2/Kcnma1/Pkd2/Ryr3/Clca2	15
GO:0004896	cytokine receptor activity	MF	0.124	0.00269	0.0237	1.63	0.0182	Cd44/Il11ra1/Cxcr3/Flt3/Il27ra/Xcr1/Csf2rb/Il17rd/Il12rb1/Il2rg/Il7r/Cd4	12
GO:0051219	phosphoprotein binding	MF	0.118	0.00275	0.024	1.62	0.0185	Cd44/Shc3/Dpysl4/She/Arrb1/Pkd2/Fgr/Dpysl3/Zap70/Bbs1/Sh2d3c/Grb10/Irs1	13
GO:0042578	phosphoric ester hydrolase activity	MF	0.084	0.00285	0.0247	1.61	0.019	Ptprz1/Pald1/Ptprd/Ptpro/Lrrk2/Ptp4a3/Inpp4b/Pde1b/Plcb1/Ptpdc1/Ptprm/Plpp3/Lhpp/Ppm1f/Enpp1/Ppef2/Pde1a/Hddc3/Bpnt1/Ppm1e/Plcb2/Pde5a/Plpp1/Nt5c3b/Smpd1/Pde8a/Pld2/Enpp2/Ptpn7/Plppr2	30
GO:0022834	ligand-gated channel activity	MF	0.109	0.00288	0.0247	1.61	0.019	Kcnj3/Grid1/Gria4/Grik1/Ryr1/P2rx2/Rasa3/Grin2b/Glrb/Gabra4/Grik2/Kcnma1/Pkd2/Ryr3/Clca2	15
GO:0016836	hydro-lyase activity	MF	0.143	0.00336	0.0283	1.55	0.0218	Cyp1b1/Car4/Car8/Cbs/L3hypdh/Echs1/Naxd/Hacd1/Echdc2	9
GO:0004180	carboxypeptidase activity	MF	0.171	0.0034	0.0284	1.55	0.0219	Cpxm2/Vash1/Naalad2/Cpe/Agbl3/Mindy1/Vash2	7
GO:0030170	pyridoxal phosphate binding	MF	0.154	0.0035	0.029	1.54	0.0223	Abat/Cbs/Pygm/Sptlc3/Kyat1/Hdc/Cth/Pygl	8
GO:0032794	GTPase activating protein binding	MF	0.227	0.00361	0.0296	1.53	0.0228	Plxnb1/Gnai1/Arl3/Gnb5/Fmnl3	5
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	MF	0.286	0.00381	0.0305	1.52	0.0235	Fads2/Fads1/Fads3/Degs2	4
GO:0030021	extracellular matrix structural constituent conferring compression resistance	MF	0.286	0.00381	0.0305	1.52	0.0235	Spock2/Bgn/Lum/Vcan	4
GO:0047555	3’,5’-cyclic-GMP phosphodiesterase activity	MF	0.286	0.00381	0.0305	1.52	0.0235	Pde1b/Pde1a/Pde5a/Pde8a	4
GO:0070279	vitamin B6 binding	MF	0.151	0.00395	0.0313	1.5	0.0241	Abat/Cbs/Pygm/Sptlc3/Kyat1/Hdc/Cth/Pygl	8
GO:0042910	xenobiotic transmembrane transporter activity	MF	0.188	0.00406	0.0318	1.5	0.0245	Abcg2/Abca8b/Abcb1a/Abcc5/Abcg3/Slc43a3	6
GO:0042626	ATPase-coupled transmembrane transporter activity	MF	0.118	0.00408	0.0318	1.5	0.0245	Abcg2/Atp6v0e2/Abca5/Abcg1/Abca8b/Atp2b4/Abcd2/Atp1a2/Abcb1a/Abcc5/Abcg3/Abcg4	12
GO:0030276	clathrin binding	MF	0.138	0.00417	0.0322	1.49	0.0248	Nsg2/Syt13/Lrrk2/Ap1m1/Trpc6/Syt7/Hip1/Arrb1/Nsg1	9
GO:0023023	MHC protein complex binding	MF	0.217	0.00443	0.0335	1.48	0.0258	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa/Cd4	5
GO:0050431	transforming growth factor beta binding	MF	0.217	0.00443	0.0335	1.48	0.0258	Cd109/Tsku/Ltbp3/Nrros/Eng	5
GO:0051020	GTPase binding	MF	0.0841	0.00443	0.0335	1.48	0.0258	Rragb/Rims3/Rasgrp3/Gga2/Lrrk2/Myo5a/Mical1/Ranbp17/Dock2/Dock10/Rab34/Abi2/Rragd/Dmxl2/Rasip1/Rhobtb3/Daam2/Dennd5a/Bin1/Adcyap1r1/Net1/Fgd1/Cdc42ep5/Cav1/Cyfip2/Kif16b/Fmnl3	27
GO:0051018	protein kinase A binding	MF	0.145	0.00498	0.0361	1.44	0.0278	Wasf3/Lrrk2/Akap12/Pkia/Akap17b/Akap11/Dact1/Prkar1b	8
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	MF	0.145	0.00498	0.0361	1.44	0.0278	Grid1/Gria4/Grik1/Grin2b/Glrb/Gabra4/Grik2/Gabbr1	8
GO:0005229	intracellular calcium activated chloride channel activity	MF	0.267	0.005	0.0361	1.44	0.0278	Ano1/Ano2/Ttyh2/Clca2	4
GO:0015278	calcium-release channel activity	MF	0.267	0.005	0.0361	1.44	0.0278	Ryr1/Rasa3/Pkd2/Ryr3	4
GO:0022821	potassium ion antiporter activity	MF	0.267	0.005	0.0361	1.44	0.0278	Slc9a7/Slc24a4/Slc24a3/Slc9a5	4
GO:0061778	intracellular chloride channel activity	MF	0.267	0.005	0.0361	1.44	0.0278	Ano1/Ano2/Ttyh2/Clca2	4
GO:0008528	G protein-coupled peptide receptor activity	MF	0.103	0.00525	0.0376	1.42	0.0289	Vipr2/Npr3/Ednrb/Cxcr3/Pth1r/Aplnr/Agtr1a/Ednra/Ogfrl1/Bdkrb2/Adcyap1r1/Xcr1/Calcrl/Prokr1/F2r	15
GO:0031690	adrenergic receptor binding	MF	0.208	0.00537	0.0376	1.42	0.0289	Magi2/Bdkrb2/Arrb1/Arrb2/Dlg4	5
GO:0099604	ligand-gated calcium channel activity	MF	0.208	0.00537	0.0376	1.42	0.0289	Ryr1/Rasa3/Grin2b/Pkd2/Ryr3	5
GO:0098960	postsynaptic neurotransmitter receptor activity	MF	0.13	0.00621	0.0432	1.36	0.0332	Grid1/Gria4/Grik1/Drd4/Grin2b/Glrb/Gabra4/Grik2/Gabbr1	9
GO:0005159	insulin-like growth factor receptor binding	MF	0.25	0.00641	0.0436	1.36	0.0335	Igf1/Igf2/Arrb1/Irs1	4
GO:0005172	vascular endothelial growth factor receptor binding	MF	0.25	0.00641	0.0436	1.36	0.0335	Angpt1/Ccdc88a/Cdh5/Vegfc	4
GO:0015562	efflux transmembrane transporter activity	MF	0.25	0.00641	0.0436	1.36	0.0335	Abcg2/Abcb1a/Abcc5/Abcg3	4
GO:0050780	dopamine receptor binding	MF	0.2	0.00645	0.0436	1.36	0.0335	Grin2b/Agtr1a/Arrb2/Dlg4/Palm	5
GO:0015294	solute:cation symporter activity	MF	0.116	0.00657	0.0437	1.36	0.0337	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc2a13/Slc6a15/Slc23a2/Slc12a4/Slc38a1/Slc4a8	11
GO:0048306	calcium-dependent protein binding	MF	0.116	0.00657	0.0437	1.36	0.0337	Syn2/Myo5a/Slc24a4/Mgp/Masp1/Kcnip3/S100pbp/Atp2b4/Stx2/Pdcd6ip/S100g	11
GO:0016597	amino acid binding	MF	0.129	0.00683	0.0451	1.35	0.0347	Slc1a3/Grik1/Ddah1/Nos3/Grin2b/Hdc/Glrb/Ubr1/Prodh	9
GO:0031267	small GTPase binding	MF	0.0842	0.00691	0.0453	1.34	0.0348	Rims3/Rasgrp3/Gga2/Lrrk2/Myo5a/Mical1/Ranbp17/Dock2/Dock10/Rab34/Abi2/Dmxl2/Rasip1/Rhobtb3/Daam2/Dennd5a/Adcyap1r1/Net1/Fgd1/Cdc42ep5/Cav1/Cyfip2/Kif16b/Fmnl3	24
GO:0008013	beta-catenin binding	MF	0.115	0.0071	0.0457	1.34	0.0352	Ar/Lef1/Nos3/Cdh2/Grin2b/Gli3/Cdh5/Tcf4/Dlg5/Psen1/Dact1	11
GO:0001784	phosphotyrosine residue binding	MF	0.149	0.00739	0.0472	1.33	0.0363	Shc3/She/Fgr/Zap70/Sh2d3c/Grb10/Irs1	7
GO:0008066	glutamate receptor activity	MF	0.192	0.00767	0.0486	1.31	0.0374	Grid1/Gria4/Grik1/Grin2b/Grik2	5
GO:0097110	scaffold protein binding	MF	0.119	0.00771	0.0486	1.31	0.0374	Nlgn1/Nos3/Grin2b/Nlgn3/Fyn/Cacna1h/Dlg4/Atp2b4/Lrp4/Kif5a	10
GO:0015291	secondary active transmembrane transporter activity	MF	0.0868	0.00797	0.0499	1.3	0.0384	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc8a1/Slc9a7/Slc24a4/Slc36a4/Slc24a3/Slc8a3/Slc2a13/Slc6a15/Slc9a5/Slc23a2/Slc12a4/Slc38a1/Slco4c1/Slc4a3/Slc4a8/Ank	21
GO:0001653	peptide receptor activity	MF	0.098	0.00803	0.0499	1.3	0.0384	Vipr2/Npr3/Ednrb/Cxcr3/Pth1r/Aplnr/Agtr1a/Ednra/Ogfrl1/Bdkrb2/Adcyap1r1/Xcr1/Calcrl/Prokr1/F2r	15
GO:0008574	plus-end-directed microtubule motor activity	MF	0.235	0.00807	0.0499	1.3	0.0384	Kif1a/Stard9/Kif16b/Kif5a	4

Visualisation

bp_dot=list()
mf_dot=list()
cc_dot=list()
upset=list()
for (i in 1:length(fc)) {
  x <- fc[i] %>% as.character()
  
  # extract the enriched GO terms from each ontology
  bp <- enrichGO_sig[[x]] %>% dplyr::filter(ontology == "BP") 
  mf <- enrichGO_sig[[x]] %>% dplyr::filter(ontology == "MF")
  cc <- enrichGO_sig[[x]] %>% dplyr::filter(ontology == "CC")

  # bp dot plot, save
  bp_dot[[x]] <- ggplot(bp[1:15, ]) +
    geom_point(aes(x = GeneRatio, y = reorder(Description, GeneRatio), colour = logFDR, size = Count)) +
    scale_color_gradient(low = "dodgerblue3", high = "firebrick3", limits = c(0, NA)) +
    scale_size(range = c(.5,3)) +
    ggtitle("Biological Process") +
    ylab(label = "") +
    xlab(label = "Gene Ratio") +
    labs(color = expression("-log"[10] * "FDR"), size = "Gene Counts")
  ggsave(filename = paste0("bp_dot_", fc[i], ".svg"), plot = bp_dot[[x]] + pub, path = here::here("2_plots/go/"), 
         width = 200, height = 120, units = "mm")

  # mf dot plot, save
  mf_dot[[x]] <- ggplot(mf[1:15, ]) +
    geom_point(aes(x = GeneRatio, y = reorder(Description, GeneRatio), colour = logFDR, size = Count)) +
    scale_color_gradient(low = "dodgerblue3", high = "firebrick3", limits = c(0, NA)) +
    scale_size(range = c(.5,3)) +
    ggtitle("Molecular Function") +
    ylab(label = "") +
    xlab(label = "Gene Ratio") +
    labs(color = expression("-log"[10] * "FDR"), size = "Gene Counts")
  ggsave(filename = paste0("mf_dot_", fc[i], ".svg"), plot = mf_dot[[x]] + pub, path = here::here("2_plots/go/"), 
         width = 200, height = 120, units = "mm")

  # cc dot plot, save
  cc_dot[[x]] <- ggplot(cc[1:15, ]) +
    geom_point(aes(x = GeneRatio, y = reorder(Description, GeneRatio), colour = logFDR, size = Count)) +
    scale_color_gradient(low = "dodgerblue3", high = "firebrick3", limits = c(0, NA)) +
    scale_size(range = c(.5,3)) +
    ggtitle("Cellular Components") +
    ylab(label = "") +
    xlab(label = "Gene Ratio") +
    labs(color = expression("-log"[10] * "FDR"), size = "Gene Counts")
  ggsave(filename = paste0("cc_dot_", fc[i], ".svg"), plot = cc_dot[[x]] + pub, path = here::here("2_plots/go/"), 
         width = 200, height = 120, units = "mm")
  
  upset[[x]] <- upsetplot(x = enrichGO[[x]], 10)
  ggsave(filename = paste0("upset_", fc[i], ".svg"), plot = upset[[x]], path = here::here("2_plots/go/"), width = 250, height = 166, units = "mm")
}

bp_dot[[1]]

mf_dot[[1]]

cc_dot[[1]]

upset[[1]]

# display the top 30 most sig
enrichGO_sig[[2]] %>% 
  dplyr::mutate_if(is.numeric, funs(as.character(signif(.,3)))) %>% 
  kable(caption = "Significantly enriched GO terms") %>%
  kable_styling(bootstrap_options = c("striped", "hover")) %>%
  scroll_box(height = "600px")

Significantly enriched GO terms
	Description	ontology	GeneRatio	pvalue	p.adjust	logFDR	qvalue	geneID	Count
GO:0030198	extracellular matrix organization	BP	0.194	1.46e-23	3.71e-20	19.4	2.52e-20	Col11a1/Ihh/Cyp1b1/Mmp16/Hmcn1/Sfrp2/Vit/Sema5a/Scara3/Col14a1/Adamts20/Col4a6/Ddr2/Prdm5/Npnt/Phldb2/Spock2/Adamts16/Tgfbi/Ets1/Adamts19/Fn1/Mmp2/Foxf1/Col16a1/Fkbp10/Nid1/Olfml2b/Has2/Egflam/Adamts1/Col9a2/Col13a1/Postn/Smoc1/Loxl3/Adamts10/Tnfrsf11b/Emilin1/Tie1/Ndnf/Adamts7/Col5a2/Col15a1/Ltbp3/Mmp19/Adamtsl1/P3h1/Vwa1/Abi3bp/Dpt/Ccn2/Crtap/Efemp2/Olfml2a/Col23a1/Ntng1/Adamts17/Cav1/Col18a1/Itga8	61
GO:0043062	extracellular structure organization	BP	0.193	1.74e-23	3.71e-20	19.4	2.52e-20	Col11a1/Ihh/Cyp1b1/Mmp16/Hmcn1/Sfrp2/Vit/Sema5a/Scara3/Col14a1/Adamts20/Col4a6/Ddr2/Prdm5/Npnt/Phldb2/Spock2/Adamts16/Tgfbi/Ets1/Adamts19/Fn1/Mmp2/Foxf1/Col16a1/Fkbp10/Nid1/Olfml2b/Has2/Egflam/Adamts1/Col9a2/Col13a1/Postn/Smoc1/Loxl3/Adamts10/Tnfrsf11b/Emilin1/Tie1/Ndnf/Adamts7/Col5a2/Col15a1/Ltbp3/Mmp19/Adamtsl1/P3h1/Vwa1/Abi3bp/Dpt/Ccn2/Crtap/Efemp2/Olfml2a/Col23a1/Ntng1/Adamts17/Cav1/Col18a1/Itga8	61
GO:0045229	external encapsulating structure organization	BP	0.192	2.07e-23	3.71e-20	19.4	2.52e-20	Col11a1/Ihh/Cyp1b1/Mmp16/Hmcn1/Sfrp2/Vit/Sema5a/Scara3/Col14a1/Adamts20/Col4a6/Ddr2/Prdm5/Npnt/Phldb2/Spock2/Adamts16/Tgfbi/Ets1/Adamts19/Fn1/Mmp2/Foxf1/Col16a1/Fkbp10/Nid1/Olfml2b/Has2/Egflam/Adamts1/Col9a2/Col13a1/Postn/Smoc1/Loxl3/Adamts10/Tnfrsf11b/Emilin1/Tie1/Ndnf/Adamts7/Col5a2/Col15a1/Ltbp3/Mmp19/Adamtsl1/P3h1/Vwa1/Abi3bp/Dpt/Ccn2/Crtap/Efemp2/Olfml2a/Col23a1/Ntng1/Adamts17/Cav1/Col18a1/Itga8	61
GO:0006816	calcium ion transport	BP	0.155	2.15e-20	2.89e-17	16.5	1.97e-17	Nalcn/Cacna1c/Ryr1/Spink1/Jph4/Igf1/Adra1a/Nos3/Slc8a1/Drd4/Ednrb/Slc24a4/Cachd1/Cacna2d1/Myo5a/Icam1/Grin2b/Stc1/Prkd1/Cxcr3/Cxcl12/Slc24a3/Cacna1e/Ank2/Slc8a3/Calca/Nalf1/Thy1/Trpc6/Gja4/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Adcyap1r1/Xcl1/Htr2a/Tspan13/Bin1/Stac2/Pkd1/Cacng7/Dysf/Asph/Ryr3/Selenon/Xcr1/Rrad/Cd84/Cacna1h/Arrb2/Ptger3/Calcrl/Ccn2/Fyn/Pkd2/Slc25a23/Gstm7/Atp2b4/Gimap5/Atp1a2/Gnb5/Gimap3/Cav1/Usp2/Cacna1a/Cacnb4	68
GO:0045785	positive regulation of cell adhesion	BP	0.145	1.99e-19	2.14e-16	15.7	1.46e-16	Ihh/Efnb3/Vit/Col26a1/Angpt1/Lef1/Mdk/Itga4/Cd83/Kdr/Igf1/Npnt/Chst2/Cd44/Spock2/Nrp1/Fermt2/Ets1/Fn1/Foxf1/Col16a1/Icam1/Nid1/Tek/Cxcl12/Has2/Cdh13/Egflam/Pik3r6/Gli3/Calca/Podxl/Tnfsf13b/Thy1/Plpp3/Cd1d1/Smoc1/Coro1a/Ppm1f/Itgal/Il27ra/H2-Ab1/Vegfc/Sele/Havcr2/Sox12/H2-Ob/Emilin1/Igf2/Ndnf/Xcl1/Pcsk5/Nckap1l/H2-Eb1/Dysf/Abi3bp/Net1/H2-Aa/Adam19/Stat5b/Gimap5/Zap70/Gimap3/Efemp2/St3gal4/Apbb1ip/Ptn/Il12rb1/Cav1/Il2rg	70
GO:0034329	cell junction assembly	BP	0.15	4.44e-19	3.98e-16	15.4	2.71e-16	Gpc6/Gap43/Sdk2/Wnt11/Kdr/Plxnb1/Ptprd/St8sia2/Nlgn1/Epb41l3/Ptpro/Phldb2/Mpdz/Nrp1/Fermt2/Cdh2/Lrrc4b/Cdh6/Fn1/Col16a1/Nptx1/Mef2c/Tek/Thsd1/Jam3/Shank2/Obsl1/Cldn8/Cdh10/Adgrl1/Slitrk3/Cdh5/Thy1/Plxnd1/Abi2/Epha3/Ppm1f/Nlgn3/Aplnr/Esam/Myo9a/Nptxr/Sh3bp1/Nfasc/Limch1/Arhgap6/Cdh11/Magi2/Gjc1/Pecam1/Snai1/Epha7/Heg1/Pcdh17/Dchs1/Dlc1/Cldn5/Bhlhb9/Cux2/Nphp1/Dlg5/Arhgef9/Cav1/Cacna1a/Itgb4/Cldn1	66
GO:0031589	cell-substrate adhesion	BP	0.155	1.05e-17	8.06e-15	14.1	5.48e-15	Ptprz1/Vit/Col26a1/Angpt1/Mdk/Itga4/Kdr/Npnt/Phldb2/Lamc3/Spock2/Nrp1/Fermt2/Itgb7/Fn1/Foxf1/Col16a1/Nid1/Tek/Thsd1/Has2/Jam3/Cdh13/Egflam/Itga1/Frem1/Col13a1/Postn/Thy1/Smoc1/Coro1a/Epha3/Ppm1f/Itgal/Limch1/Vegfc/Arhgap6/Hoxd3/Sned1/Tmeff2/Emilin1/Ndnf/Pecam1/Parvg/Itga7/Pcsk5/Parvb/Epdr1/Dlc1/Abi3bp/Net1/Ccn2/Efemp2/Ptn/Ntng1/Cd96/Itga8/Itgb4	58
GO:0050808	synapse organization	BP	0.136	4.39e-17	2.47e-14	13.6	1.68e-14	Gpc6/Gap43/Sdk2/Lrrc4c/Plxnb1/Ptprd/St8sia2/Nlgn1/Ptpro/Rims3/Pdzrn3/P2rx2/Nrp1/Cdh2/Lrrc4b/Wasf3/Lrrk2/Nptx1/Mef2c/Myo5a/Pfn2/Grin2b/Shank2/Pcdhgc3/Obsl1/Adgrl1/Ppfia2/Slc8a3/Slitrk3/Plxnd1/Dock10/Glrb/Kif1a/Abi2/Ppfia4/Epha3/Nlgn3/Dgkb/Nptxr/Nfasc/Arhgef15/Apoe/Prrt1/Palld/Sparcl1/Magi2/Caprin2/Epha7/Erc2/Pcdh17/Lrfn2/Nfatc4/Fyn/Bhlhb9/Dlg4/Cux2/Palm/Dlg5/Syngap1/Rab39b/Ngef/Arhgef9/Ptn/Ntng1/Dact1/Cacna1a/Cacnb4	67
GO:0048754	branching morphogenesis of an epithelial tube	BP	0.208	4.59e-17	2.47e-14	13.6	1.68e-14	Ihh/Sfrp2/Sema5a/Wnt6/Angpt1/Hhip/Ar/Lef1/Mdk/Hoxd11/Kdr/Nog/Igf1/Tbx2/Npnt/Cd44/Hoxa11/Nrp1/Adamts16/Gpc3/Areg/Foxf1/Tek/Cxcl12/Gli3/Tcf21/Gdf7/Plxnd1/Mgp/Agtr1a/Rasip1/Tbx3/Tie1/Ednra/Pkd1/Ptch1/Dchs1/Nfatc4/Fat4/Dlg5	40
GO:0007224	smoothened signaling pathway	BP	0.226	1.03e-16	5.02e-14	13.3	3.42e-14	Gli1/Ihh/Hhip/Evc2/Nog/Ptch2/Evc/Kif7/Dzip1l/Gpc3/Arl6/Foxf1/Serpine2/Cibar1/Bbs7/Zfp423/Armc9/Gli3/Ift57/Ptpdc1/Rab34/Wnt9a/Gpr161/Enpp1/Dync2h1/Hipk2/Arl3/Cfap410/Ptch1/Tmem231/Ttc26/Ttbk2/Dzip1/Rab23/Dlg5/Gpc2	36
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	BP	0.192	4.21e-16	1.89e-13	12.7	1.28e-13	Gpc6/Prtg/Hmcn1/Pcdh18/Sdk2/Mcam/Itga4/Lrrc4c/Ptprd/Nlgn1/Cdh2/Lrrc4b/Cdh6/Tenm3/Dab1/Cdh13/Pcdhgc3/Obsl1/Cdh10/Adgrl1/Slitrk3/Cdh5/Pcdh19/Ptprm/Pcdh12/Epha3/Esam/Itgal/Palld/Sele/Sparcl1/Cdh11/Magi2/Pecam1/Pcdh17/Dchs1/Fat3/Fat4/Ntng1/Pcdhb14/Cldn1	41
GO:0001655	urogenital system development	BP	0.145	1e-15	4.15e-13	12.4	2.83e-13	Stra6/Wnt6/Angpt1/Ar/Wnt11/Pygo1/Hoxd11/Nog/Cyp7b1/Igf1/Npnt/Ptpro/Cd44/Hoxa11/Nrp1/Adamts16/Gpc3/Ednrb/Lrrk2/Mmp2/Foxf1/Mef2c/Id3/Osr2/Nid1/Id4/Tek/Enpep/Gdf11/Adamts1/Gli3/Tcf21/Lrp2/Plxnd1/Tshz3/Prdm1/Cdkn1c/Cplane1/Enpp1/Agtr1a/Heyl/Dync2h1/Ednra/Pcsk5/Smad9/Pkd1/Epha7/Arl3/Ptch1/Osr1/Dchs1/Aqp11/Pkd2/Fat4/Dlg5/Itga8	56
GO:0001667	ameboidal-type cell migration	BP	0.135	1.45e-15	5.56e-13	12.3	3.78e-13	Cyp1b1/Sema5a/Angpt1/Wnt11/Itga4/Kdr/Igf1/Evl/Sema5b/Ddr2/Zeb2/Nos3/Slc8a1/Sema7a/Nrp1/Ets1/Cdh2/Ednrb/Itgb7/Fn1/Mef2c/Pfn2/Ptp4a3/Stc1/Prkd1/Tek/Cxcl12/Has2/Cdh13/Akap12/Edn3/Vash1/Calca/Cdh5/Plxnd1/Syde1/Plpp3/Ptprm/Kit/Ppm1f/Jcad/Sh3bp1/Prr5l/Vegfc/Apoe/Ednra/Igf2/Daam2/Pecam1/Sema3g/Kitl/Hdac9/Atp2b4/Akt3/Fstl1/Sema6a/Arsb/Adgra2/Mapre2/Cygb/Itgb4	61
GO:0034765	regulation of ion transmembrane transport	BP	0.129	3.11e-15	1.04e-12	12	7.1e-13	Kcnb2/Nalcn/Kcnj3/Hecw2/Kcna6/Cacna1c/Kcnd2/Kcnd3/Nlgn1/Tcaf1/Slc8a1/Scn4b/Drd4/Scn1a/Fxyd5/Kcnq5/Cacna2d1/Mef2c/Myo5a/Prkd1/Cxcr3/Cacna1e/Edn3/Ank2/Plcb1/Thy1/Trpc6/Scn2a/Coro1a/Nlgn3/Aplnr/Cracr2a/Prrt1/Agtr1a/Kcnma1/Kcnc4/Ednra/Tspan13/Bin1/Stac2/Cacng7/Dysf/Kcnip3/Fhl1/Asph/Selenon/Osr1/Rrad/Cacna1h/Kcng4/Ptger3/Fyn/Pkd2/Scn3a/Dlg4/Gstm7/Atp2b4/Atp1a2/Gnb5/Abcb1a/Kcnq4/Cav1/Cacna1a/Cacnb4	64
GO:0001822	kidney development	BP	0.152	5.49e-15	1.7e-12	11.8	1.16e-12	Stra6/Wnt6/Angpt1/Wnt11/Pygo1/Hoxd11/Nog/Npnt/Ptpro/Cd44/Hoxa11/Nrp1/Adamts16/Gpc3/Ednrb/Lrrk2/Mef2c/Id3/Osr2/Nid1/Tek/Enpep/Gdf11/Adamts1/Gli3/Tcf21/Lrp2/Plxnd1/Tshz3/Prdm1/Cdkn1c/Cplane1/Enpp1/Agtr1a/Heyl/Dync2h1/Ednra/Pcsk5/Smad9/Pkd1/Epha7/Arl3/Ptch1/Osr1/Dchs1/Aqp11/Pkd2/Fat4/Dlg5/Itga8	50
GO:0061138	morphogenesis of a branching epithelium	BP	0.178	5.69e-15	1.7e-12	11.8	1.16e-12	Ihh/Hgf/Sfrp2/Sema5a/Wnt6/Angpt1/Hhip/Ar/Lef1/Mdk/Hoxd11/Kdr/Nog/Igf1/Tbx2/Npnt/Cd44/Hoxa11/Nrp1/Adamts16/Gpc3/Areg/Foxf1/Tek/Cxcl12/Gli3/Tcf21/Gdf7/Plxnd1/Mgp/Agtr1a/Rasip1/Tbx3/Tie1/Ednra/Pkd1/Ptch1/Dchs1/Nfatc4/Fat4/Dlg5	41
GO:0072001	renal system development	BP	0.148	8.09e-15	2.29e-12	11.6	1.56e-12	Stra6/Wnt6/Angpt1/Wnt11/Pygo1/Hoxd11/Nog/Npnt/Ptpro/Cd44/Hoxa11/Nrp1/Adamts16/Gpc3/Ednrb/Lrrk2/Foxf1/Mef2c/Id3/Osr2/Nid1/Tek/Enpep/Gdf11/Adamts1/Gli3/Tcf21/Lrp2/Plxnd1/Tshz3/Prdm1/Cdkn1c/Cplane1/Enpp1/Agtr1a/Heyl/Dync2h1/Ednra/Pcsk5/Smad9/Pkd1/Epha7/Arl3/Ptch1/Osr1/Dchs1/Aqp11/Pkd2/Fat4/Dlg5/Itga8	51
GO:0070588	calcium ion transmembrane transport	BP	0.157	9.96e-15	2.68e-12	11.6	1.82e-12	Nalcn/Cacna1c/Ryr1/Slc8a1/Drd4/Ednrb/Slc24a4/Cacna2d1/Myo5a/Grin2b/Prkd1/Cxcr3/Slc24a3/Cacna1e/Ank2/Slc8a3/Nalf1/Thy1/Trpc6/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Xcl1/Htr2a/Tspan13/Bin1/Stac2/Pkd1/Cacng7/Dysf/Asph/Ryr3/Selenon/Xcr1/Rrad/Ptger3/Fyn/Pkd2/Slc25a23/Gstm7/Atp2b4/Atp1a2/Gnb5/Cacna1a/Cacnb4	47
GO:0051924	regulation of calcium ion transport	BP	0.157	3.58e-14	8.92e-12	11	6.07e-12	Cacna1c/Spink1/Jph4/Igf1/Nos3/Slc8a1/Drd4/Cacna2d1/Myo5a/Icam1/Stc1/Prkd1/Cxcr3/Cxcl12/Ank2/Calca/Thy1/Trpc6/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Adcyap1r1/Tspan13/Bin1/Stac2/Dysf/Asph/Selenon/Rrad/Cd84/Arrb2/Ptger3/Fyn/Pkd2/Gstm7/Gimap5/Atp1a2/Gnb5/Gimap3/Cav1/Usp2/Cacna1a/Cacnb4	45
GO:0060562	epithelial tube morphogenesis	BP	0.137	3.65e-14	8.92e-12	11	6.07e-12	Ihh/Sfrp2/Sema5a/Wnt6/Angpt1/Hhip/Ar/Lef1/Mdk/Hoxd11/Kdr/Nog/Igf1/Tbx2/Zeb2/Npnt/Cd44/Hoxa11/Nrp1/Adamts16/Gpc3/Areg/Foxf1/Mef2c/Tek/Cxcl12/Gli3/Tcf21/Lrp2/Gdf7/Ift57/Plxnd1/Cecr2/Mgp/Aplnr/Agtr1a/Rasip1/Tbx3/Tie1/Ednra/Prickle1/Pkd1/Epha7/Ptch1/Ipmk/Osr1/Dchs1/Dlc1/Nfatc4/Pkd2/Fzd2/Rab23/Fat4/Dlg5	54
GO:0006874	cellular calcium ion homeostasis	BP	0.124	4.41e-14	1.03e-11	11	7.02e-12	Kcnk3/Cacna1c/Ryr1/Kdr/Adra1a/Slc8a1/P2rx2/Pygm/Bok/Ednrb/Slc24a4/Cacna2d1/Myo5a/Inpp4b/Grin2b/Lpar4/Stc1/Prkd1/Cxcr3/Slc24a3/Cacna1e/Ptgfr/Edn3/Ank2/Slc8a3/Calca/Cdh5/Pth1r/Nalf1/Thy1/Trpc6/Coro1a/Aplnr/Kctd17/Grik2/Apoe/Cd38/Agtr1a/Ednra/Adcyap1r1/Bdkrb2/Xcl1/Htr2a/Pkd1/Asph/Ryr3/Selenon/Xcr1/Ptger3/Fyn/Pkd2/Slc25a23/Fzd2/Dlg4/Gstm7/Atp2b4/Gimap5/Atp1a2/Gimap3/Cav1/Cacna1a/Cacnb4	62
GO:0031345	negative regulation of cell projection organization	BP	0.177	7.42e-14	1.66e-11	10.8	1.13e-11	Ptprz1/Efnb3/Map2/Sema5a/Evl/Sema5b/Nlgn1/Sema7a/Nrp1/Cspg4/Ntm/Dab1/Lrrk2/Abi3/Pfn2/Grin2b/Thy1/Trpc6/Epha3/Minar1/Nlgn3/Tsku/Apoe/Cd38/Sema3g/Dennd5a/Rtn4rl1/Epha7/Nfatc4/Neo1/Fyn/Fat3/Xylt1/Dpysl3/Syngap1/Sema6a/Ngef/Cep97	38
GO:0010959	regulation of metal ion transport	BP	0.128	1.31e-13	2.83e-11	10.5	1.92e-11	Hecw2/Cacna1c/Spink1/Jph4/Igf1/Nos3/Slc8a1/Scn4b/Drd4/Fxyd5/Cacna2d1/Myo5a/Icam1/Stc1/Serpine2/Prkd1/Cxcr3/Cxcl12/Edn3/Ank2/Calca/Plcb1/Thy1/Trpc6/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Adcyap1r1/Htr2a/Tspan13/Bin1/Stac2/Dysf/Kcnip3/Fhl1/Asph/Selenon/Osr1/Rrad/Cd84/Arrb2/Ptger3/Fyn/Pkd2/Gstm7/Atp2b4/Gimap5/Akt3/Atp1a2/Gnb5/Gimap3/Cav1/Usp2/Cacna1a/Cacnb4	57
GO:0060402	calcium ion transport into cytosol	BP	0.19	1.76e-13	3.65e-11	10.4	2.48e-11	Cacna1c/Ryr1/Adra1a/Slc8a1/Slc24a4/Cacna2d1/Myo5a/Grin2b/Prkd1/Cxcr3/Cacna1e/Ank2/Slc8a3/Calca/Nalf1/Thy1/Coro1a/Aplnr/Agtr1a/Ednra/Adcyap1r1/Xcl1/Htr2a/Asph/Ryr3/Selenon/Xcr1/Fyn/Pkd2/Gstm7/Gimap5/Gimap3/Cav1/Cacna1a	34
GO:0050673	epithelial cell proliferation	BP	0.124	1.86e-13	3.71e-11	10.4	2.52e-11	Gli1/Ihh/Hgf/Sfrp2/Sema5a/Ar/Mdk/Itga4/Cd109/Kdr/Agap2/Nog/Cyp7b1/Igf1/Tbx2/Gkn3/Fst/Gpc3/Ednrb/Areg/Ccnd2/Mef2c/Osr2/Prkd1/Tek/Cxcr3/Cxcl12/Has2/Cdh13/Vash1/Calca/Ift57/Stxbp4/Ptprm/Kit/Ppp1r16b/Aplnr/Cdkn1c/Jcad/Vegfc/Apoe/Agtr1a/Tie1/Ednra/Igf2/Klf9/Twist2/Dysf/Ptch1/Osr1/Aqp11/Apln/Akt3/Egfl7/Ptn/Cav1/Vash2/Igfbp4/Cldn1	59
GO:0060401	cytosolic calcium ion transport	BP	0.179	2.22e-13	4.26e-11	10.4	2.9e-11	Cacna1c/Ryr1/Adra1a/Slc8a1/Slc24a4/Cacna2d1/Myo5a/Grin2b/Prkd1/Cxcr3/Cacna1e/Ank2/Slc8a3/Calca/Nalf1/Thy1/Coro1a/Aplnr/Agtr1a/Ednra/Adcyap1r1/Xcl1/Htr2a/Asph/Ryr3/Selenon/Xcr1/Ccn2/Fyn/Pkd2/Slc25a23/Gstm7/Gimap5/Gimap3/Cav1/Cacna1a	36
GO:0003018	vascular process in circulatory system	BP	0.166	2.85e-13	5.29e-11	10.3	3.6e-11	Angpt1/Cacna1c/Kdr/Ddah1/Adra1a/Nos3/Slc8a1/Cbs/Npr3/Fermt2/Ednrb/Mmp2/Icam1/Wdr35/Ptp4a3/Abcg2/Akap12/Edn3/Itga1/Calca/Cdh5/Htr1b/Ptprm/Gucy1a1/Apoe/Cd38/Agtr1a/Kcnma1/Ednra/Bdkrb2/Htr2a/Pde5a/Cldn5/Ptger3/Apln/Atp1a2/Abcb1a/Abcg3/Cav1	39
GO:0048736	appendage development	BP	0.176	3.52e-13	6.11e-11	10.2	4.16e-11	Ihh/Sfrp2/Lef1/Cacna1c/Hoxd10/Hoxd11/Nog/Aff3/Pkdcc/Tbx2/Rnf165/Hoxa11/Fermt2/Gpc3/Hoxd9/Hoxa10/Osr2/Cibar1/Bbs7/Flvcr1/Gli3/Wnt9a/Smoc1/Cplane1/Enpp1/Tbx3/Dync2h1/Pcsk5/Hoxa9/Ptch1/Tmem231/Asph/Osr1/Ttbk2/Rab23/Itgb4	36
GO:0060173	limb development	BP	0.176	3.52e-13	6.11e-11	10.2	4.16e-11	Ihh/Sfrp2/Lef1/Cacna1c/Hoxd10/Hoxd11/Nog/Aff3/Pkdcc/Tbx2/Rnf165/Hoxa11/Fermt2/Gpc3/Hoxd9/Hoxa10/Osr2/Cibar1/Bbs7/Flvcr1/Gli3/Wnt9a/Smoc1/Cplane1/Enpp1/Tbx3/Dync2h1/Pcsk5/Hoxa9/Ptch1/Tmem231/Asph/Osr1/Ttbk2/Rab23/Itgb4	36
GO:0007409	axonogenesis	BP	0.12	8.43e-13	1.42e-10	9.85	9.64e-11	Gap43/Epha8/Prtg/Ptprz1/Efnb3/Map2/Sema5a/Pla2g10/Itga4/Lrrc4c/Dcc/Nog/Plxnb1/Evl/Sema5b/Rnf165/Zeb2/Ptpro/Sema7a/Nrp1/Cdh2/Fn1/Dab1/Nptx1/Mef2c/Cxcl12/Arhgef25/Edn3/Gli3/Lrp2/Slitrk3/Gdf7/Thy1/Plxnd1/Ptprm/Ndn/Lama2/Epha3/Nlgn3/Matn2/Tsku/Nfasc/Apoe/Cdh11/Ednra/Sema3g/Rtn4rl1/Nin/Epha7/Chodl/Ptch1/Neo1/Unc5c/Brsk1/Syngap1/Sema6a/Ntng1/Nrn1/Cacna1a	59
GO:0007160	cell-matrix adhesion	BP	0.162	1.15e-12	1.87e-10	9.73	1.27e-10	Itga4/Kdr/Npnt/Phldb2/Nrp1/Fermt2/Itgb7/Fn1/Col16a1/Nid1/Tek/Thsd1/Jam3/Cdh13/Itga1/Frem1/Col13a1/Postn/Thy1/Epha3/Ppm1f/Itgal/Limch1/Vegfc/Arhgap6/Hoxd3/Sned1/Emilin1/Pecam1/Itga7/Pcsk5/Epdr1/Dlc1/Ccn2/Efemp2/Cd96/Itga8/Itgb4	38
GO:0050678	regulation of epithelial cell proliferation	BP	0.128	1.31e-12	2.07e-10	9.68	1.41e-10	Gli1/Ihh/Sfrp2/Sema5a/Ar/Mdk/Itga4/Cd109/Kdr/Agap2/Nog/Cyp7b1/Igf1/Gkn3/Gpc3/Ednrb/Ccnd2/Mef2c/Osr2/Prkd1/Tek/Cxcr3/Cxcl12/Has2/Cdh13/Vash1/Ift57/Stxbp4/Ptprm/Ppp1r16b/Aplnr/Cdkn1c/Jcad/Vegfc/Apoe/Agtr1a/Tie1/Ednra/Igf2/Klf9/Twist2/Dysf/Ptch1/Osr1/Aqp11/Apln/Akt3/Egfl7/Ptn/Cav1/Vash2/Cldn1	52
GO:0051480	regulation of cytosolic calcium ion concentration	BP	0.128	2.11e-12	3.24e-10	9.49	2.2e-10	Kcnk3/Cacna1c/Ryr1/Kdr/Adra1a/Slc8a1/P2rx2/Bok/Ednrb/Slc24a4/Cacna2d1/Myo5a/Grin2b/Lpar4/Prkd1/Cxcr3/Cacna1e/Ptgfr/Ank2/Slc8a3/Calca/Pth1r/Nalf1/Thy1/Trpc6/Coro1a/Aplnr/Cd38/Agtr1a/Ednra/Adcyap1r1/Bdkrb2/Xcl1/Htr2a/Pkd1/Asph/Ryr3/Selenon/Xcr1/Ptger3/Fyn/Pkd2/Fzd2/Dlg4/Gstm7/Atp2b4/Gimap5/Atp1a2/Gimap3/Cav1/Cacna1a	51
GO:0035107	appendage morphogenesis	BP	0.184	2.26e-12	3.28e-10	9.48	2.23e-10	Ihh/Sfrp2/Lef1/Cacna1c/Hoxd10/Hoxd11/Nog/Aff3/Pkdcc/Tbx2/Rnf165/Hoxa11/Gpc3/Hoxd9/Hoxa10/Osr2/Cibar1/Flvcr1/Gli3/Wnt9a/Cplane1/Enpp1/Tbx3/Dync2h1/Pcsk5/Hoxa9/Ptch1/Tmem231/Asph/Osr1/Ttbk2/Rab23	32
GO:0035108	limb morphogenesis	BP	0.184	2.26e-12	3.28e-10	9.48	2.23e-10	Ihh/Sfrp2/Lef1/Cacna1c/Hoxd10/Hoxd11/Nog/Aff3/Pkdcc/Tbx2/Rnf165/Hoxa11/Gpc3/Hoxd9/Hoxa10/Osr2/Cibar1/Flvcr1/Gli3/Wnt9a/Cplane1/Enpp1/Tbx3/Dync2h1/Pcsk5/Hoxa9/Ptch1/Tmem231/Asph/Osr1/Ttbk2/Rab23	32
GO:0032970	regulation of actin filament-based process	BP	0.126	3.07e-12	4.34e-10	9.36	2.95e-10	Kank4/Sema5a/Mdk/Wnt11/Cacna1c/Evl/Phldb2/Ccdc88a/Hcls1/Nrp1/Fermt2/Tmod2/Wasf3/Mef2c/Pfn2/Icam1/Stc1/Tek/Jam3/Ank2/Coro1a/Abi2/Epha3/Ppm1f/Esam/Sh3bp1/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Daam2/Pecam1/Ppm1e/Scin/Cnn2/Nckap1l/Carmil3/Rhobtb3/Bin1/Myo1f/Arhgap28/Dlc1/Cacna1h/Ptger3/Ccn2/Fgr/Atp1a2/Cdc42ep5/Cav1/Cyfip2/Plekhh2	52
GO:1903039	positive regulation of leukocyte cell-cell adhesion	BP	0.153	7.12e-12	9.58e-10	9.02	6.52e-10	Ihh/Efnb3/Lef1/Mdk/Itga4/Cd83/Igf1/Chst2/Cd44/Ets1/Icam1/Has2/Pik3r6/Gli3/Tnfsf13b/Thy1/Cd1d1/Coro1a/Itgal/Il27ra/H2-Ab1/Sele/Havcr2/Sox12/H2-Ob/Igf2/Xcl1/Nckap1l/H2-Eb1/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/St3gal4/Il12rb1/Cav1/Il2rg	38
GO:0010977	negative regulation of neuron projection development	BP	0.185	9.09e-12	1.17e-09	8.93	7.93e-10	Ptprz1/Efnb3/Map2/Sema5a/Sema5b/Nlgn1/Sema7a/Nrp1/Cspg4/Ntm/Dab1/Lrrk2/Thy1/Epha3/Minar1/Nlgn3/Tsku/Apoe/Cd38/Sema3g/Dennd5a/Rtn4rl1/Epha7/Neo1/Fat3/Xylt1/Dpysl3/Syngap1/Sema6a/Ngef	30
GO:1902903	regulation of supramolecular fiber organization	BP	0.126	1.07e-11	1.33e-09	8.87	9.08e-10	Kank4/Map2/Sema5a/Wnt11/Evl/Phldb2/Ccdc88a/Hcls1/Nrp1/Fermt2/Tmod2/Wasf3/Mef2c/Pfn2/Icam1/Cdh5/Coro1a/Abi2/Ppm1f/Rp1/Esam/Sh3bp1/Limch1/Tubb4a/Nox4/Arhgef15/Apoe/Arhgap6/Tmeff2/Emilin1/Daam2/Pecam1/Ppm1e/Scin/Nckap1l/Slain1/Carmil3/Nin/Bin1/Dysf/Arhgap28/Ttbk2/Dlc1/Ccn2/Efemp2/Cdc42ep5/Cav1/Cyfip2/Plekhh2	49
GO:0090287	regulation of cellular response to growth factor stimulus	BP	0.14	1.17e-11	1.43e-09	8.85	9.7e-10	Sfrp2/Angpt1/Hhip/Cd109/Kdr/Nog/Rnf165/Zeb2/Npnt/Fst/Gpc3/Ptp4a3/Tek/Zfp423/Lrp2/Cdh5/Pbld2/Zeb1/Cdkn1c/Jcad/Tsku/Vegfc/Emilin1/Tcf4/Spred3/Kcp/Tnfaip6/Hipk2/Nrros/Zfyve9/Neo1/Il17rd/Apln/Atp2b4/Fstl1/Sema6a/Lats2/Adgra2/Cav1/Cyfip2/Itga8/Tmprss6	42
GO:0031346	positive regulation of cell projection organization	BP	0.12	1.25e-11	1.49e-09	8.83	1.01e-09	Ptprz1/Hgf/Sema5a/Acsl6/Fez1/Mdk/Dcc/Plxnb1/Ptprd/Nlgn1/Zeb2/Lrrc7/Ccdc88a/Sema7a/Nrp1/Fn1/Tenm3/Serpine2/Prkd1/Cxcl12/Tbc1d24/Obsl1/Gprc5b/Adamts1/Serpini1/Plxnd1/Abi2/Kit/Epha3/Rp1/Kctd17/Apoe/Magi2/Eps8l1/Caprin2/Ndnf/Crocc/Nin/Chodl/P3h1/Ttbk2/Dzip1/Fyn/Bhlhb9/Dlg4/Cux2/Palm/Dpysl3/Cdc42ep5/Arsb/Ptn/Gpc2/Cpeb1	53
GO:0007204	positive regulation of cytosolic calcium ion concentration	BP	0.13	1.71e-11	1.96e-09	8.71	1.33e-09	Cacna1c/Ryr1/Kdr/Adra1a/Slc8a1/Ednrb/Slc24a4/Cacna2d1/Myo5a/Grin2b/Lpar4/Prkd1/Cxcr3/Cacna1e/Ptgfr/Ank2/Slc8a3/Calca/Pth1r/Nalf1/Thy1/Trpc6/Coro1a/Aplnr/Cd38/Agtr1a/Ednra/Adcyap1r1/Bdkrb2/Xcl1/Htr2a/Pkd1/Asph/Ryr3/Selenon/Xcr1/Ptger3/Fyn/Pkd2/Fzd2/Dlg4/Gstm7/Gimap5/Gimap3/Cav1/Cacna1a	46
GO:0007159	leukocyte cell-cell adhesion	BP	0.125	2.27e-11	2.55e-09	8.59	1.73e-09	Ihh/Efnb3/Lef1/Mdk/Itga4/Cd83/Igf1/Chst2/Cd44/Ets1/Itgb7/Icam1/Podxl2/Cxcl12/Has2/Pik3r6/Gli3/Calca/Tnfsf13b/Thy1/Cd1d1/Msn/Loxl3/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Sele/Havcr2/Sox12/H2-Ob/Igf2/Pecam1/Xcl1/Nckap1l/H2-Eb1/Pde5a/H2-Aa/Stat5b/Gimap5/Zap70/Dlg5/Gimap3/St3gal4/Il12rb1/Cav1/Il2rg	48
GO:0050890	cognition	BP	0.128	2.78e-11	3.05e-09	8.52	2.07e-09	Stra6/Ptprz1/Mdk/Cacna1c/Nog/Cyp7b1/Jph4/Igf1/Aph1b/Aff2/Drd4/Tmod2/Ccnd2/Chst10/Shc3/Mef2c/Grin2b/B4galt2/Pde1b/Adcy3/Shank2/Cacna1e/Slc8a3/Plcb1/Eif2ak4/Mme/Scn2a/Abi2/Kit/Nlgn3/Apoe/Prrt1/Igf2/Htr2a/Pde5a/Nfatc4/Mgat3/Bhlhb9/Cux2/Atp1a2/Brsk1/Syngap1/St3gal4/Ptn/Ddhd2/Itga8	46
GO:0022407	regulation of cell-cell adhesion	BP	0.115	3.22e-11	3.47e-09	8.46	2.36e-09	Ihh/Efnb3/Lef1/Mdk/Itga4/Cd83/Igf1/Abat/Chst2/Cd44/Ets1/Tenm3/Icam1/Serpine2/Cxcl12/Has2/Pik3r6/Gli3/Podxl/Tnfsf13b/Thy1/Plpp3/Cd1d1/Loxl3/Coro1a/Ccm2l/Ppm1f/Btla/Itgal/Il27ra/H2-Ab1/Sele/Havcr2/Sox12/H2-Ob/Magi2/Igf2/Xcl1/Nckap1l/Epha7/H2-Eb1/Pde5a/Ptger3/H2-Aa/Adam19/Stat5b/Gimap5/Zap70/Dlg5/Gimap3/St3gal4/Il12rb1/Cav1/Il2rg	54
GO:0022409	positive regulation of cell-cell adhesion	BP	0.138	3.57e-11	3.76e-09	8.42	2.56e-09	Ihh/Efnb3/Lef1/Mdk/Itga4/Cd83/Igf1/Chst2/Cd44/Ets1/Icam1/Has2/Pik3r6/Gli3/Podxl/Tnfsf13b/Thy1/Plpp3/Cd1d1/Coro1a/Itgal/Il27ra/H2-Ab1/Sele/Havcr2/Sox12/H2-Ob/Igf2/Xcl1/Nckap1l/H2-Eb1/H2-Aa/Adam19/Stat5b/Gimap5/Zap70/Gimap3/St3gal4/Il12rb1/Cav1/Il2rg	41
GO:0010811	positive regulation of cell-substrate adhesion	BP	0.193	3.72e-11	3.85e-09	8.41	2.62e-09	Vit/Col26a1/Mdk/Kdr/Npnt/Spock2/Nrp1/Fermt2/Fn1/Foxf1/Col16a1/Nid1/Tek/Has2/Cdh13/Egflam/Thy1/Smoc1/Ppm1f/Vegfc/Emilin1/Ndnf/Pcsk5/Abi3bp/Net1/Efemp2/Ptn	27
GO:0022604	regulation of cell morphogenesis	BP	0.13	4.43e-11	4.5e-09	8.35	3.06e-09	Mdk/Kdr/Plxnb1/Ptprd/Epb41l3/Cpne5/Cd44/Nrp1/Fermt2/Wasf3/Fn1/Icam1/Has2/Tbc1d24/Obsl1/Postn/Plxnd1/Msn/Coro1a/Kit/Myo9a/Caprin2/Itga7/Arap3/Slc23a2/Rhobtb3/Parvb/Cfap410/Cacng7/Syne3/Dlc1/Net1/Fyn/Bhlhb9/Fgd1/Dlg4/Cux2/Fgr/Palm/Cdc42ep5/Ptn/Arhgap15/Ntng1/Plekho1	44
GO:0043113	receptor clustering	BP	0.26	4.53e-11	4.52e-09	8.35	3.07e-09	Itga4/Nlgn1/Lrrc7/Cdh2/Itgb7/Grin2b/Slitrk3/Thy1/Glrb/Dlg2/Itgal/Grik2/Apoe/Magi2/Tnfaip6/Dlg4/Syngap1/Arhgef9/Ptn/Cacna1a	20
GO:0006936	muscle contraction	BP	0.134	5.14e-11	5.02e-09	8.3	3.42e-09	Sgcd/Cacna1c/Ryr1/Kcnd3/Tbx2/Adra1a/Npnt/Abat/Slc8a1/Scn4b/Mybpc1/P2rx2/Tmod2/Scn1a/Ednrb/Cacna2d1/Stc1/Edn3/Ank2/Slc8a3/Calca/Tshz3/Gucy1a1/Kit/Cd38/Kcnma1/Tbx3/Ednra/Bdkrb2/Htr2a/Myl3/Bin1/Stac2/Ryr3/Pde5a/Cacna1h/Ptger3/Calcrl/Ccn2/Atp2b4/Atp1a2/Cav1	42
GO:0042391	regulation of membrane potential	BP	0.113	1.07e-10	1.02e-08	7.99	6.92e-09	Kcnk3/Nalcn/Grik1/Cacna1c/Begain/Kcnd2/Kdr/Kcnd3/Nlgn1/Adra1a/Abat/Celf4/Rims3/Slc8a1/Scn4b/Drd4/Stx1b/P2rx2/Scn1a/Bok/Slc24a4/Cacna2d1/Lrrk2/Ano1/Mef2c/Grin2b/Tbc1d24/Ank2/Slc8a3/Glrb/Gabra4/Slc29a1/Scn2a/Nlgn3/Grik2/Kcnma1/Kcnc4/Bin1/Fhl1/Mpp2/Cacna1h/Scn3a/Dlg4/Cux2/Gimap5/Gimap3/Ptn/Piezo2/Cav1/Slc4a8/Cacna1a/Pid1/Cacnb4	53
GO:0097485	neuron projection guidance	BP	0.143	1.08e-10	1.02e-08	7.99	6.92e-09	Gap43/Epha8/Prtg/Efnb3/Sema5a/Pla2g10/Dcc/Nog/Plxnb1/Evl/Sema5b/Rnf165/Ptpro/Sema7a/Nrp1/Dpysl4/Mef2c/Cxcl12/Arhgef25/Edn3/Gli3/Lrp2/Gdf7/Plxnd1/Ptprm/Lama2/Epha3/Matn2/Nfasc/Ednra/Sema3g/Rtn4rl1/Epha7/Ptch1/Neo1/Unc5c/Sema6a	37
GO:0006939	smooth muscle contraction	BP	0.205	1.18e-10	1.09e-08	7.96	7.44e-09	Cacna1c/Tbx2/Adra1a/Npnt/Abat/Slc8a1/P2rx2/Ednrb/Edn3/Calca/Tshz3/Gucy1a1/Kit/Cd38/Kcnma1/Tbx3/Ednra/Bdkrb2/Htr2a/Ptger3/Calcrl/Atp2b4/Atp1a2/Cav1	24
GO:0003012	muscle system process	BP	0.116	1.32e-10	1.2e-08	7.92	8.17e-09	Ar/Sgcd/Cacna1c/Col14a1/Ryr1/Igf1/Kcnd3/Tbx2/Adra1a/Npnt/Abat/Nos3/Slc8a1/Scn4b/Mybpc1/P2rx2/Tmod2/Scn1a/Ednrb/Cacna2d1/Mef2c/Stc1/Edn3/Ank2/Slc8a3/Calca/Tshz3/Gucy1a1/Kit/Cd38/Kcnma1/Tbx3/Ednra/Bdkrb2/Htr2a/Myl3/Cmya5/Bin1/Stac2/Ryr3/Selenon/Pde5a/Cacna1h/Ptger3/Calcrl/Ccn2/Pi16/Atp2b4/Atp1a2/Cav1	50
GO:0060485	mesenchyme development	BP	0.134	1.47e-10	1.32e-08	7.88	8.95e-09	Sfrp2/Sema5a/Lef1/Mdk/Wnt11/Itga4/Nog/Tbx2/Sema5b/Mark1/Zeb2/Nos3/Phldb2/Sema7a/Nrp1/Fermt2/Cdh2/Ednrb/Fn1/Foxf1/Mef2c/Erg/Has2/Edn3/Tcf21/Loxl3/Epha3/Aplnr/Tbx3/Heyl/Ednra/Snai1/Sema3g/Spred3/Kitl/Osr1/Dchs1/Il17rd/Dlg5/Sema6a	40
GO:0010810	regulation of cell-substrate adhesion	BP	0.15	1.69e-10	1.49e-08	7.83	1.01e-08	Ptprz1/Vit/Col26a1/Mdk/Kdr/Npnt/Phldb2/Spock2/Nrp1/Fermt2/Fn1/Foxf1/Col16a1/Nid1/Tek/Has2/Cdh13/Egflam/Postn/Thy1/Smoc1/Epha3/Ppm1f/Limch1/Vegfc/Arhgap6/Emilin1/Ndnf/Pcsk5/Dlc1/Abi3bp/Net1/Efemp2/Ptn	34
GO:0050679	positive regulation of epithelial cell proliferation	BP	0.152	2.08e-10	1.77e-08	7.75	1.21e-08	Ihh/Sema5a/Ar/Mdk/Itga4/Kdr/Agap2/Nog/Cyp7b1/Igf1/Ccnd2/Osr2/Prkd1/Cxcl12/Has2/Cdh13/Stxbp4/Ppp1r16b/Aplnr/Jcad/Vegfc/Agtr1a/Igf2/Twist2/Dysf/Osr1/Apln/Akt3/Egfl7/Ptn/Cav1/Vash2/Cldn1	33
GO:0016055	Wnt signaling pathway	BP	0.113	2.34e-10	1.93e-08	7.71	1.31e-08	Gli1/Ndp/Sfrp2/Sema5a/Wnt6/Lef1/Mdk/Apcdd1/Wnt11/Pygo1/Nog/Mark1/Zeb2/Ptpro/Nkd1/Cd44/Fermt2/Tert/Cdh2/Gpc3/Arl6/Ednrb/Lrrk2/Tmem237/Rbms3/Gprc5b/Gli3/Peg12/Cpe/Plpp3/Wnt9a/Dkk3/Znrf3/Tsku/Apoe/Enpp1/Caprin2/Ednra/Daam2/Prickle1/Pkd1/Tle1/Nfatc4/Mgat3/Pkd2/Fzd2/Lats2/Adgra2/Cav1/Dact1/Nkd2	51
GO:0001505	regulation of neurotransmitter levels	BP	0.142	2.4e-10	1.93e-08	7.71	1.31e-08	Syn2/Maob/Slc6a2/Nlgn1/Adra1a/Abat/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Mef2c/Pfn2/Pde1b/Maoa/Edn3/Ppfia2/Htr1b/Naalad2/Syde1/Cadps/Slc29a1/Lin7a/Syt7/Prrt2/Kcnc4/Htr2a/Erc2/Ncs1/Atp1a2/Brsk1/Nrn1/Stx2/Slc4a8/Cacna1a/Cacnb4	36
GO:0035296	regulation of tube diameter	BP	0.168	2.45e-10	1.93e-08	7.71	1.31e-08	Cacna1c/Kdr/Adra1a/Nos3/Slc8a1/Cbs/Npr3/Ednrb/Mmp2/Icam1/Wdr35/Edn3/Itga1/Calca/Htr1b/Ptprm/Gucy1a1/Apoe/Cd38/Agtr1a/Kcnma1/Ednra/Bdkrb2/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1	29
GO:0097746	blood vessel diameter maintenance	BP	0.168	2.45e-10	1.93e-08	7.71	1.31e-08	Cacna1c/Kdr/Adra1a/Nos3/Slc8a1/Cbs/Npr3/Ednrb/Mmp2/Icam1/Wdr35/Edn3/Itga1/Calca/Htr1b/Ptprm/Gucy1a1/Apoe/Cd38/Agtr1a/Kcnma1/Ednra/Bdkrb2/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1	29
GO:1903037	regulation of leukocyte cell-cell adhesion	BP	0.125	2.47e-10	1.93e-08	7.71	1.31e-08	Ihh/Efnb3/Lef1/Mdk/Itga4/Cd83/Igf1/Chst2/Cd44/Ets1/Icam1/Cxcl12/Has2/Pik3r6/Gli3/Tnfsf13b/Thy1/Cd1d1/Loxl3/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Sele/Havcr2/Sox12/H2-Ob/Igf2/Xcl1/Nckap1l/H2-Eb1/Pde5a/H2-Aa/Stat5b/Gimap5/Zap70/Dlg5/Gimap3/St3gal4/Il12rb1/Cav1/Il2rg	43
GO:0099173	postsynapse organization	BP	0.155	2.53e-10	1.95e-08	7.71	1.32e-08	Gap43/Ptprd/Nlgn1/Nrp1/Cdh2/Lrrc4b/Lrrk2/Nptx1/Grin2b/Shank2/Ppfia2/Slitrk3/Dock10/Glrb/Kif1a/Abi2/Nlgn3/Dgkb/Nptxr/Apoe/Magi2/Caprin2/Epha7/Lrfn2/Fyn/Bhlhb9/Dlg4/Cux2/Syngap1/Ngef/Arhgef9/Ptn	32
GO:0198738	cell-cell signaling by wnt	BP	0.113	2.74e-10	2.05e-08	7.69	1.39e-08	Gli1/Ndp/Sfrp2/Sema5a/Wnt6/Lef1/Mdk/Apcdd1/Wnt11/Pygo1/Nog/Mark1/Zeb2/Ptpro/Nkd1/Cd44/Fermt2/Tert/Cdh2/Gpc3/Arl6/Ednrb/Lrrk2/Tmem237/Rbms3/Gprc5b/Gli3/Peg12/Cpe/Plpp3/Wnt9a/Dkk3/Znrf3/Tsku/Apoe/Enpp1/Caprin2/Ednra/Daam2/Prickle1/Pkd1/Tle1/Nfatc4/Mgat3/Pkd2/Fzd2/Lats2/Adgra2/Cav1/Dact1/Nkd2	51
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	BP	0.205	2.79e-10	2.05e-08	7.69	1.39e-08	Prtg/Hmcn1/Pcdh18/Sdk2/Cdh2/Cdh6/Tenm3/Cdh13/Pcdhgc3/Obsl1/Cdh10/Cdh5/Pcdh19/Ptprm/Pcdh12/Esam/Palld/Cdh11/Pecam1/Dchs1/Fat3/Fat4/Pcdhb14	23
GO:0035150	regulation of tube size	BP	0.167	2.82e-10	2.05e-08	7.69	1.39e-08	Cacna1c/Kdr/Adra1a/Nos3/Slc8a1/Cbs/Npr3/Ednrb/Mmp2/Icam1/Wdr35/Edn3/Itga1/Calca/Htr1b/Ptprm/Gucy1a1/Apoe/Cd38/Agtr1a/Kcnma1/Ednra/Bdkrb2/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1	29
GO:1903169	regulation of calcium ion transmembrane transport	BP	0.167	2.82e-10	2.05e-08	7.69	1.39e-08	Cacna1c/Slc8a1/Drd4/Cacna2d1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Cracr2a/Agtr1a/Ednra/Tspan13/Bin1/Stac2/Dysf/Asph/Selenon/Rrad/Ptger3/Fyn/Pkd2/Gstm7/Atp1a2/Gnb5/Cacna1a/Cacnb4	29
GO:0045765	regulation of angiogenesis	BP	0.13	3.28e-10	2.32e-08	7.63	1.58e-08	Cyp1b1/Hgf/Sfrp2/Sema5a/Hhip/Mdk/Kdr/Ddah1/Nos3/Nrp1/Ets1/Tert/Prkd1/Tek/Cxcr3/Pik3r6/Adamts1/Vash1/Cdh5/Plxnd1/Ptprm/Minar1/Ppp1r16b/Aplnr/Jcad/Vegfc/Ecscr/Agtr1a/Emilin1/Tie1/Igf2/Tcf4/Hipk2/Cldn5/Atp2b4/Akt3/Sema6a/Ptn/Adgra2/Vash2	40
GO:0030326	embryonic limb morphogenesis	BP	0.182	3.32e-10	2.32e-08	7.63	1.58e-08	Ihh/Sfrp2/Lef1/Cacna1c/Hoxd10/Hoxd11/Nog/Aff3/Tbx2/Hoxa11/Gpc3/Hoxd9/Hoxa10/Osr2/Flvcr1/Gli3/Wnt9a/Cplane1/Tbx3/Dync2h1/Hoxa9/Ptch1/Tmem231/Osr1/Ttbk2/Rab23	26
GO:0035113	embryonic appendage morphogenesis	BP	0.182	3.32e-10	2.32e-08	7.63	1.58e-08	Ihh/Sfrp2/Lef1/Cacna1c/Hoxd10/Hoxd11/Nog/Aff3/Tbx2/Hoxa11/Gpc3/Hoxd9/Hoxa10/Osr2/Flvcr1/Gli3/Wnt9a/Cplane1/Tbx3/Dync2h1/Hoxa9/Ptch1/Tmem231/Osr1/Ttbk2/Rab23	26
GO:0007411	axon guidance	BP	0.14	3.74e-10	2.58e-08	7.59	1.75e-08	Gap43/Epha8/Prtg/Efnb3/Sema5a/Pla2g10/Dcc/Nog/Plxnb1/Evl/Sema5b/Rnf165/Ptpro/Sema7a/Nrp1/Mef2c/Cxcl12/Arhgef25/Edn3/Gli3/Lrp2/Gdf7/Plxnd1/Ptprm/Lama2/Epha3/Matn2/Nfasc/Ednra/Sema3g/Rtn4rl1/Epha7/Ptch1/Neo1/Unc5c/Sema6a	36
GO:0097553	calcium ion transmembrane import into cytosol	BP	0.174	4.16e-10	2.83e-08	7.55	1.93e-08	Cacna1c/Ryr1/Slc8a1/Slc24a4/Myo5a/Grin2b/Prkd1/Cxcr3/Cacna1e/Ank2/Slc8a3/Nalf1/Thy1/Coro1a/Aplnr/Agtr1a/Ednra/Xcl1/Htr2a/Asph/Ryr3/Selenon/Xcr1/Fyn/Pkd2/Gstm7/Cacna1a	27
GO:1901342	regulation of vasculature development	BP	0.129	4.84e-10	3.25e-08	7.49	2.21e-08	Cyp1b1/Hgf/Sfrp2/Sema5a/Hhip/Mdk/Kdr/Ddah1/Nos3/Nrp1/Ets1/Tert/Prkd1/Tek/Cxcr3/Pik3r6/Adamts1/Vash1/Cdh5/Plxnd1/Ptprm/Minar1/Ppp1r16b/Aplnr/Jcad/Vegfc/Ecscr/Agtr1a/Emilin1/Tie1/Igf2/Tcf4/Hipk2/Cldn5/Atp2b4/Akt3/Sema6a/Ptn/Adgra2/Vash2	40
GO:0010631	epithelial cell migration	BP	0.128	5.86e-10	3.87e-08	7.41	2.63e-08	Cyp1b1/Sema5a/Angpt1/Kdr/Igf1/Evl/Zeb2/Nos3/Nrp1/Ets1/Mef2c/Pfn2/Ptp4a3/Stc1/Prkd1/Tek/Has2/Cdh13/Vash1/Calca/Cdh5/Plxnd1/Plpp3/Ptprm/Kit/Ppm1f/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Daam2/Pecam1/Hdac9/Atp2b4/Akt3/Fstl1/Arsb/Adgra2/Mapre2	40
GO:0032956	regulation of actin cytoskeleton organization	BP	0.12	5.9e-10	3.87e-08	7.41	2.63e-08	Kank4/Sema5a/Mdk/Wnt11/Evl/Phldb2/Ccdc88a/Hcls1/Nrp1/Fermt2/Tmod2/Wasf3/Mef2c/Pfn2/Icam1/Tek/Jam3/Coro1a/Abi2/Epha3/Ppm1f/Esam/Sh3bp1/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Daam2/Pecam1/Ppm1e/Scin/Nckap1l/Carmil3/Rhobtb3/Bin1/Myo1f/Arhgap28/Dlc1/Ccn2/Fgr/Cdc42ep5/Cyfip2/Plekhh2	44
GO:1904062	regulation of cation transmembrane transport	BP	0.118	6.68e-10	4.33e-08	7.36	2.95e-08	Hecw2/Cacna1c/Nlgn1/Slc8a1/Scn4b/Drd4/Fxyd5/Cacna2d1/Mef2c/Myo5a/Prkd1/Cxcr3/Edn3/Ank2/Plcb1/Thy1/Coro1a/Nlgn3/Aplnr/Cracr2a/Prrt1/Agtr1a/Ednra/Tspan13/Bin1/Stac2/Cacng7/Dysf/Kcnip3/Fhl1/Asph/Selenon/Osr1/Rrad/Ptger3/Fyn/Pkd2/Dlg4/Gstm7/Atp2b4/Atp1a2/Gnb5/Cav1/Cacna1a/Cacnb4	45
GO:0090132	epithelium migration	BP	0.127	7.09e-10	4.54e-08	7.34	3.09e-08	Cyp1b1/Sema5a/Angpt1/Kdr/Igf1/Evl/Zeb2/Nos3/Nrp1/Ets1/Mef2c/Pfn2/Ptp4a3/Stc1/Prkd1/Tek/Has2/Cdh13/Vash1/Calca/Cdh5/Plxnd1/Plpp3/Ptprm/Kit/Ppm1f/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Daam2/Pecam1/Hdac9/Atp2b4/Akt3/Fstl1/Arsb/Adgra2/Mapre2	40
GO:0014848	urinary tract smooth muscle contraction	BP	0.643	7.17e-10	4.54e-08	7.34	3.09e-08	Cacna1c/Tbx2/P2rx2/Tshz3/Kcnma1/Tbx3/Htr2a/Ptger3/Atp2b4	9
GO:0016358	dendrite development	BP	0.126	8.56e-10	5.35e-08	7.27	3.64e-08	Ptprz1/Map2/Hecw2/Ptprd/Nlgn1/Mark1/Tet1/Mpdz/Nrp1/Dab1/Lrrk2/Mef2c/Tbc1d24/Obsl1/Ppfia2/D16Ertd472e/Dock10/Trpc6/Kif1a/Abi2/Nlgn3/Matn2/Apoe/Caprin2/Prex2/Sarm1/Nfatc4/Fyn/Bhlhb9/Dlg4/Cux2/Fat3/Palm/Dlg5/Syngap1/Ngef/Ptn/Bbs1/Dact1/Cacna1a	40
GO:0048762	mesenchymal cell differentiation	BP	0.14	9.52e-10	5.89e-08	7.23	4.01e-08	Sfrp2/Sema5a/Lef1/Mdk/Wnt11/Nog/Sema5b/Mark1/Zeb2/Phldb2/Sema7a/Nrp1/Fermt2/Cdh2/Ednrb/Fn1/Mef2c/Erg/Has2/Edn3/Tcf21/Loxl3/Epha3/Tbx3/Heyl/Ednra/Snai1/Sema3g/Spred3/Kitl/Osr1/Il17rd/Dlg5/Sema6a	34
GO:0009100	glycoprotein metabolic process	BP	0.123	1.01e-09	6.19e-08	7.21	4.21e-08	Col11a1/Ihh/St6gal2/Itm2a/Igf1/St8sia2/St8sia4/Gxylt2/Tet1/Man2a2/Spock2/Uggt2/Chst10/Soat1/Tmtc1/B3galnt1/Fut10/Egflam/Plcb1/Galnt16/Mamdc2/St6galnac4/Fbxo17/St3gal2/Eogt/Ggta1/Ndnf/Adamts7/St8sia6/Galntl6/Bgn/Poglut2/Aqp11/Mgat3/B3gnt5/Xylt1/Dse/St6galnac6/St3gal4/Large1/Alg14	41
GO:0007015	actin filament organization	BP	0.109	1.18e-09	7.15e-08	7.15	4.87e-08	Kank4/Hmcn1/Sema5a/Wnt11/Evl/Phldb2/Ccdc88a/Hcls1/Nrp1/Fermt2/Aif1l/Tmod2/Wasf3/Myo5a/Pfn2/Icam1/Mical1/Arhgap25/Catip/Coro1a/Abi2/Ppm1f/Esam/Sh3bp1/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Daam2/Pecam1/Ppm1e/Scin/Nckap1l/Carmil3/Hip1/Efs/Rhobtb3/Bin1/Arrb1/Myo1f/Arhgap28/Dlc1/Ccn2/Wipf1/Dpysl3/Cdc42ep5/Cyfip2/Plekhh2/Shroom1	50
GO:1901888	regulation of cell junction assembly	BP	0.145	1.22e-09	7.32e-08	7.14	4.98e-08	Gpc6/Kdr/Ptprd/St8sia2/Nlgn1/Phldb2/Nrp1/Fermt2/Lrrc4b/Col16a1/Nptx1/Mef2c/Tek/Adgrl1/Slitrk3/Thy1/Epha3/Ppm1f/Nlgn3/Aplnr/Limch1/Arhgap6/Snai1/Epha7/Dlc1/Cldn5/Bhlhb9/Cux2/Nphp1/Dlg5/Cav1/Cldn1	32
GO:0048705	skeletal system morphogenesis	BP	0.134	1.92e-09	1.13e-07	6.95	7.71e-08	Col11a1/Ihh/Mmp16/Sfrp2/Hhip/Hoxd10/Hoxd11/Nog/Thbs3/Cbs/Hoxa11/Hoxd9/Mmp2/Mef2c/Osr2/Hoxd8/Stc1/Hoxd4/Has2/Flvcr1/Gli3/Frem1/Col13a1/Wnt9a/Zeb1/Enpp1/Hoxd3/Hoxa9/Ltbp3/Twist2/Pkd1/Osr1/Ccn2/Fgr/Rab23	35
GO:0045055	regulated exocytosis	BP	0.129	2.01e-09	1.18e-07	6.93	8.01e-08	Syn2/Cacna1c/Nlgn1/Syt13/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Foxf1/Pfn2/Mical1/Ppfia2/Htr1b/Syde1/Cadps/Coro1a/Kit/Syt7/Prrt2/Htr2a/Nckap1l/Erc2/Ncs1/Myo1f/Cd84/Cacna1h/Fgr/Lat/Rab27a/Clnk/Nrn1/Stx2/Slc4a8/Cacna1a/Cacnb4	37
GO:0008589	regulation of smoothened signaling pathway	BP	0.213	2.09e-09	1.21e-07	6.92	8.24e-08	Gli1/Ihh/Hhip/Evc/Kif7/Gpc3/Arl6/Serpine2/Cibar1/Armc9/Gli3/Rab34/Wnt9a/Gpr161/Enpp1/Dync2h1/Ptch1/Ttbk2/Rab23/Dlg5	20
GO:0018212	peptidyl-tyrosine modification	BP	0.122	2.14e-09	1.22e-07	6.91	8.32e-08	Ptprz1/Hgf/Sfrp2/Angpt1/Kdr/Spink1/Igf1/Pkdcc/Ddr2/Adra1a/Cd44/Hcls1/Nrp1/Cspg4/Areg/Icam1/Itk/Tek/Tpst1/Gprc5b/Thy1/Plpp3/Abi2/Kit/Epha3/Vegfc/Nox4/Agtr1a/Igf2/Pecam1/Htr2a/Kitl/Epha7/Arrb2/Fyn/Dlg4/Fgr/Zap70/Il12rb1/Cav1	40
GO:0001936	regulation of endothelial cell proliferation	BP	0.162	2.3e-09	1.3e-07	6.89	8.84e-08	Sema5a/Mdk/Itga4/Kdr/Igf1/Mef2c/Prkd1/Tek/Cxcr3/Cxcl12/Cdh13/Vash1/Ptprm/Ppp1r16b/Aplnr/Jcad/Vegfc/Apoe/Agtr1a/Tie1/Igf2/Dysf/Apln/Akt3/Egfl7/Cav1/Vash2	27
GO:0110053	regulation of actin filament organization	BP	0.13	2.42e-09	1.34e-07	6.87	9.12e-08	Kank4/Sema5a/Wnt11/Evl/Phldb2/Ccdc88a/Hcls1/Nrp1/Fermt2/Tmod2/Wasf3/Pfn2/Icam1/Coro1a/Abi2/Ppm1f/Esam/Sh3bp1/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Daam2/Pecam1/Ppm1e/Scin/Nckap1l/Carmil3/Bin1/Arhgap28/Dlc1/Ccn2/Cdc42ep5/Cyfip2/Plekhh2	36
GO:0008360	regulation of cell shape	BP	0.166	2.68e-09	1.47e-07	6.83	1e-07	Kdr/Plxnb1/Epb41l3/Fermt2/Wasf3/Fn1/Icam1/Plxnd1/Msn/Coro1a/Kit/Itga7/Arap3/Rhobtb3/Parvb/Cfap410/Syne3/Dlc1/Fyn/Fgd1/Fgr/Palm/Cdc42ep5/Ptn/Arhgap15/Plekho1	26
GO:0030336	negative regulation of cell migration	BP	0.127	3.25e-09	1.77e-07	6.75	1.2e-07	Cyp1b1/Sfrp2/Wnt11/Nog/Evl/Tcaf1/Phldb2/Drd4/Mef2c/Pfn2/Stc1/Cxcl12/Vash1/Plcb1/Thy1/Ptprm/Gpr173/Il27ra/Robo4/Limch1/Apoe/Tmeff2/Magi2/Emilin1/Tie1/Cd200/Cnn2/Arap3/Tnfaip6/Dlc1/Cldn5/Atp2b4/Egfl7/Dpysl3/Dlg5/Ptn/Cygb	37
GO:0006836	neurotransmitter transport	BP	0.136	3.61e-09	1.94e-07	6.71	1.32e-07	Syn2/Slc6a2/Nlgn1/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Htr1b/Slc6a15/Syde1/Cadps/Slc29a1/Lin7a/Syt7/Prrt2/Kcnc4/Htr2a/Sv2c/Erc2/Ncs1/Atp1a2/Brsk1/Nrn1/Stx2/Slc4a8/Cacna1a/Cacnb4	33
GO:0001935	endothelial cell proliferation	BP	0.153	4.17e-09	2.21e-07	6.66	1.5e-07	Sema5a/Mdk/Itga4/Kdr/Igf1/Mef2c/Prkd1/Tek/Cxcr3/Cxcl12/Cdh13/Vash1/Calca/Ptprm/Ppp1r16b/Aplnr/Jcad/Vegfc/Apoe/Agtr1a/Tie1/Igf2/Dysf/Apln/Akt3/Egfl7/Cav1/Vash2	28
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.133	4.18e-09	2.21e-07	6.66	1.5e-07	Sfrp2/Cd109/Kdr/Nog/Rnf165/Zeb2/Npnt/Fst/Gpc3/Gdf11/Zfp423/Lrp2/Gdf7/Cdh5/Pbld2/Zeb1/Gdf10/Cdkn1c/Tsku/Magi2/Emilin1/Spred3/Kcp/Tnfaip6/Hipk2/Nrros/Zfyve9/Neo1/Il17rd/Fstl1/Lats2/Cav1/Itga8/Tmprss6	34
GO:0019932	second-messenger-mediated signaling	BP	0.123	4.63e-09	2.42e-07	6.62	1.64e-07	Sgcd/Kdr/Spink1/Nr5a2/Igf1/Nos3/Slc8a1/Cbs/Drd4/Gnai1/Ednrb/Slc24a4/Lrrk2/Gucy1a2/Cxcr3/Cdh13/Ptgfr/Edn3/Ank2/Adgrl1/Gucy1b1/Gucy1a1/Aplnr/Itgal/Apoe/Agtr1a/Ndnf/Adcyap1r1/Cap2/Cmya5/Rasd2/Xcr1/Pde5a/Nfatc4/Ptger3/Atp2b4/Zap70/Lat	38
GO:0060348	bone development	BP	0.132	5.12e-09	2.65e-07	6.58	1.8e-07	Ihh/Mmp16/Sfrp2/Hoxd11/Ryr1/Kdr/Plxnb1/Igf1/Ddr2/Evc/Thbs3/Cbs/Hoxa11/Mef2c/Osr2/Stc1/Has2/Lrrc17/Gli3/Frem1/Col13a1/Fli1/Kit/Enpp1/Adamts7/Tal1/Smad9/Ltbp3/Bgn/P3h1/Dchs1/Xylt1/Rab23/Fat4	34
GO:0050803	regulation of synapse structure or activity	BP	0.129	5.21e-09	2.66e-07	6.57	1.81e-07	Gpc6/Ptprd/St8sia2/Nlgn1/Ptpro/Rims3/Cdh2/Lrrc4b/Lrrk2/Nptx1/Mef2c/Grin2b/Shank2/Adgrl1/Ppfia2/Slitrk3/Kif1a/Abi2/Nlgn3/Dgkb/Arhgef15/Apoe/Sparcl1/Magi2/Caprin2/Epha7/Lrfn2/Nfatc4/Fyn/Bhlhb9/Cux2/Dlg5/Syngap1/Ngef/Ptn	35
GO:0007269	neurotransmitter secretion	BP	0.151	5.34e-09	2.66e-07	6.57	1.81e-07	Syn2/Nlgn1/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Htr1b/Syde1/Cadps/Lin7a/Syt7/Prrt2/Kcnc4/Htr2a/Erc2/Ncs1/Brsk1/Nrn1/Stx2/Slc4a8/Cacna1a/Cacnb4	28
GO:0099643	signal release from synapse	BP	0.151	5.34e-09	2.66e-07	6.57	1.81e-07	Syn2/Nlgn1/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Htr1b/Syde1/Cadps/Lin7a/Syt7/Prrt2/Kcnc4/Htr2a/Erc2/Ncs1/Brsk1/Nrn1/Stx2/Slc4a8/Cacna1a/Cacnb4	28
GO:0018108	peptidyl-tyrosine phosphorylation	BP	0.12	5.35e-09	2.66e-07	6.57	1.81e-07	Ptprz1/Hgf/Sfrp2/Angpt1/Kdr/Spink1/Igf1/Pkdcc/Ddr2/Adra1a/Cd44/Hcls1/Nrp1/Cspg4/Areg/Icam1/Itk/Tek/Gprc5b/Thy1/Plpp3/Abi2/Kit/Epha3/Vegfc/Nox4/Agtr1a/Igf2/Pecam1/Htr2a/Kitl/Epha7/Arrb2/Fyn/Dlg4/Fgr/Zap70/Il12rb1/Cav1	39
GO:0001938	positive regulation of endothelial cell proliferation	BP	0.202	5.43e-09	2.68e-07	6.57	1.82e-07	Sema5a/Mdk/Itga4/Kdr/Igf1/Prkd1/Cxcl12/Cdh13/Ppp1r16b/Aplnr/Jcad/Vegfc/Agtr1a/Igf2/Dysf/Apln/Akt3/Egfl7/Cav1/Vash2	20
GO:0072073	kidney epithelium development	BP	0.164	6.22e-09	3.02e-07	6.52	2.05e-07	Wnt6/Hoxd11/Nog/Npnt/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Ednrb/Mef2c/Gdf11/Gli3/Tcf21/Tshz3/Agtr1a/Heyl/Ednra/Smad9/Epha7/Ptch1/Osr1/Dchs1/Aqp11/Fat4	25
GO:0007162	negative regulation of cell adhesion	BP	0.121	6.61e-09	3.18e-07	6.5	2.16e-07	Ihh/Cyp1b1/Ptprz1/Sema5a/Angpt1/Lef1/Mdk/Plxnb1/Abat/Phldb2/Cd44/Dab1/Mmp2/Serpine2/Cxcl12/Jam3/Cdh13/Gli3/Podxl/Postn/Plxnd1/Loxl3/Ccm2l/Ppm1f/Btla/H2-Ab1/Arhgap6/Havcr2/Nckap1l/Myo1f/Pde5a/Dlc1/Ptger3/H2-Aa/Gimap5/Dlg5/Gimap3/Sema6a	38
GO:0051271	negative regulation of cellular component movement	BP	0.121	7.22e-09	3.44e-07	6.46	2.34e-07	Cyp1b1/Sfrp2/Wnt11/Nog/Evl/Tcaf1/Phldb2/Drd4/Mef2c/Pfn2/Stc1/Cxcl12/Vash1/Plcb1/Thy1/Ptprm/Gpr173/Il27ra/Robo4/Limch1/Apoe/Tmeff2/Magi2/Emilin1/Tie1/Cd200/Cnn2/Arap3/Tnfaip6/Bin1/Dlc1/Cldn5/Atp2b4/Egfl7/Dpysl3/Dlg5/Ptn/Cygb	38
GO:0048608	reproductive structure development	BP	0.103	7.53e-09	3.55e-07	6.45	2.42e-07	Ndp/Tex15/Stra6/Sfrp2/Angpt1/Ar/Lef1/Itga4/Kdr/Nog/Cyp7b1/Igf1/Nos3/Fst/Slc8a1/Cd44/Hoxa11/Hoxa10/Il11ra1/Mmp2/Icam1/Id4/Serpine2/Adamts1/Vash1/Tcf21/Lrp2/Gdf7/Syde1/Prdm1/Lfng/Pcdh12/Kit/Cdkn1c/Tbx3/Igf2/Snai1/Hoxa9/Rhobtb3/Kitl/Tnfaip6/Arrb1/Pkd1/Osr1/Arrb2/Pkd2/Stat5b/Abcb1a/Ptn/Vash2	50
GO:0050807	regulation of synapse organization	BP	0.129	8.38e-09	3.92e-07	6.41	2.67e-07	Gpc6/Ptprd/St8sia2/Nlgn1/Ptpro/Rims3/Cdh2/Lrrc4b/Lrrk2/Nptx1/Mef2c/Grin2b/Shank2/Adgrl1/Ppfia2/Slitrk3/Kif1a/Abi2/Nlgn3/Dgkb/Arhgef15/Apoe/Sparcl1/Magi2/Caprin2/Epha7/Lrfn2/Nfatc4/Fyn/Bhlhb9/Cux2/Dlg5/Ngef/Ptn	34
GO:0048880	sensory system development	BP	0.107	8.85e-09	4.11e-07	6.39	2.79e-07	Ndp/Tmem132e/Stra6/Ihh/Cyp1b1/Sdk2/Nhs/Cacna1c/Kdr/Tbx2/Tub/Rcn1/Zeb2/Celf4/Lamc3/Nrp1/Arl6/Tenm3/Osr2/Gdf11/Bbs7/Obsl1/Sall2/Gli3/Thy1/Zeb1/Prdm1/Tgif2/Smoc1/Ptprm/Abi2/Rp1/Cdkn1c/Tsku/Arhgef15/Pbx4/Spred3/Rorb/Lpcat1/Col5a2/Twist2/Hipk2/Tmem231/Fat3/Nphp1/Ptn	46
GO:0007043	cell-cell junction assembly	BP	0.161	9.37e-09	4.31e-07	6.37	2.93e-07	Wnt11/Epb41l3/Ptpro/Mpdz/Cdh2/Cdh6/Jam3/Cldn8/Cdh10/Cdh5/Abi2/Aplnr/Esam/Nfasc/Cdh11/Gjc1/Pecam1/Snai1/Heg1/Dchs1/Cldn5/Nphp1/Dlg5/Cav1/Cldn1	25
GO:0060070	canonical Wnt signaling pathway	BP	0.122	9.74e-09	4.44e-07	6.35	3.02e-07	Gli1/Sfrp2/Sema5a/Wnt6/Lef1/Mdk/Wnt11/Pygo1/Nog/Zeb2/Ptpro/Nkd1/Cdh2/Gpc3/Ednrb/Lrrk2/Rbms3/Gprc5b/Gli3/Peg12/Plpp3/Wnt9a/Dkk3/Znrf3/Apoe/Caprin2/Ednra/Daam2/Prickle1/Tle1/Mgat3/Fzd2/Lats2/Adgra2/Cav1/Dact1/Nkd2	37
GO:0061458	reproductive system development	BP	0.102	9.86e-09	4.46e-07	6.35	3.03e-07	Ndp/Tex15/Stra6/Sfrp2/Angpt1/Ar/Lef1/Itga4/Kdr/Nog/Cyp7b1/Igf1/Nos3/Fst/Slc8a1/Cd44/Hoxa11/Hoxa10/Il11ra1/Mmp2/Icam1/Id4/Serpine2/Adamts1/Vash1/Tcf21/Lrp2/Gdf7/Syde1/Prdm1/Lfng/Pcdh12/Kit/Cdkn1c/Tbx3/Igf2/Snai1/Hoxa9/Rhobtb3/Kitl/Tnfaip6/Arrb1/Pkd1/Osr1/Arrb2/Pkd2/Stat5b/Abcb1a/Ptn/Vash2	50
GO:2000146	negative regulation of cell motility	BP	0.121	1.06e-08	4.77e-07	6.32	3.24e-07	Cyp1b1/Sfrp2/Wnt11/Nog/Evl/Tcaf1/Phldb2/Drd4/Mef2c/Pfn2/Stc1/Cxcl12/Vash1/Plcb1/Thy1/Ptprm/Gpr173/Il27ra/Robo4/Limch1/Apoe/Tmeff2/Magi2/Emilin1/Tie1/Cd200/Cnn2/Arap3/Tnfaip6/Dlc1/Cldn5/Atp2b4/Egfl7/Dpysl3/Dlg5/Ptn/Cygb	37
GO:0043542	endothelial cell migration	BP	0.136	1.14e-08	5.08e-07	6.29	3.46e-07	Cyp1b1/Sema5a/Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Mef2c/Ptp4a3/Stc1/Prkd1/Tek/Cdh13/Vash1/Calca/Cdh5/Plxnd1/Plpp3/Ptprm/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Pecam1/Hdac9/Atp2b4/Akt3/Fstl1/Adgra2	31
GO:0072006	nephron development	BP	0.159	1.22e-08	5.36e-07	6.27	3.64e-07	Wnt6/Angpt1/Hoxd11/Nog/Npnt/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Ednrb/Mef2c/Nid1/Tek/Enpep/Gli3/Tcf21/Agtr1a/Heyl/Ednra/Ptch1/Osr1/Dchs1/Aqp11/Fat4	25
GO:0030318	melanocyte differentiation	BP	0.379	1.32e-08	5.67e-07	6.25	3.86e-07	Adamts20/Zeb2/Ednrb/Mef2c/Myo5a/Edn3/Gli3/Kit/Enpp1/Kitl/Rab27a	11
GO:0001654	eye development	BP	0.107	1.51e-08	6.47e-07	6.19	4.4e-07	Ndp/Stra6/Ihh/Cyp1b1/Sdk2/Nhs/Cacna1c/Kdr/Tbx2/Tub/Rcn1/Zeb2/Celf4/Lamc3/Nrp1/Arl6/Tenm3/Osr2/Gdf11/Bbs7/Obsl1/Sall2/Gli3/Thy1/Zeb1/Prdm1/Tgif2/Smoc1/Ptprm/Abi2/Rp1/Cdkn1c/Tsku/Arhgef15/Pbx4/Spred3/Rorb/Lpcat1/Col5a2/Twist2/Hipk2/Tmem231/Fat3/Nphp1/Ptn	45
GO:0030199	collagen fibril organization	BP	0.254	1.65e-08	7e-07	6.15	4.76e-07	Col11a1/Cyp1b1/Sfrp2/Col14a1/Ddr2/Fkbp10/Col13a1/Loxl3/Emilin1/Adamts7/Col5a2/P3h1/Dpt/Crtap/Efemp2	15
GO:0009581	detection of external stimulus	BP	0.168	1.67e-08	7.02e-07	6.15	4.78e-07	Col11a1/Sema5a/Igf1/Sema5b/Scn1a/Slc24a4/Ano1/Foxf1/Grin2b/Serpine2/Cxcl12/Calca/Kit/Grik2/Htr2a/Arrb1/Pkd1/Arrb2/Fyn/Pkd2/Pkdrej/Piezo2/Cacnb4	23
GO:0003007	heart morphogenesis	BP	0.123	1.76e-08	7.32e-07	6.14	4.98e-07	Col11a1/Ihh/Sfrp2/Angpt1/Wnt11/Ryr1/Nog/Tbx2/Nos3/Slc8a1/Nrp1/Foxf1/Mef2c/Erg/Tek/Has2/Adamts1/Lrp2/Ift57/Cpe/Plxnd1/Ccm2l/Aplnr/Tbx3/Heyl/Ednra/Snai1/Myl3/Heg1/Ptch1/Dchs1/Dlc1/Pkd2/Fzd2/Fat4	35
GO:0060840	artery development	BP	0.181	1.77e-08	7.32e-07	6.14	4.98e-07	Apob/Stra6/Mdk/Wnt11/Nog/Tbx2/Nrp1/Kif7/Foxf1/Fkbp10/Gli3/Lrp2/Plxnd1/Prdm1/Aplnr/Apoe/Enpp1/Ednra/Prickle1/Akt3/Efemp2	21
GO:0150063	visual system development	BP	0.106	1.88e-08	7.71e-07	6.11	5.24e-07	Ndp/Stra6/Ihh/Cyp1b1/Sdk2/Nhs/Cacna1c/Kdr/Tbx2/Tub/Rcn1/Zeb2/Celf4/Lamc3/Nrp1/Arl6/Tenm3/Osr2/Gdf11/Bbs7/Obsl1/Sall2/Gli3/Thy1/Zeb1/Prdm1/Tgif2/Smoc1/Ptprm/Abi2/Rp1/Cdkn1c/Tsku/Arhgef15/Pbx4/Spred3/Rorb/Lpcat1/Col5a2/Twist2/Hipk2/Tmem231/Fat3/Nphp1/Ptn	45
GO:0035249	synaptic transmission, glutamatergic	BP	0.179	2.07e-08	8.38e-07	6.08	5.7e-07	Grid1/Gria4/Grik1/Nlgn1/Aph1b/Cdh2/Lrrk2/Shc3/Mef2c/Myo5a/Grin2b/Serpine2/Shank2/Htr1b/Tshz3/Nlgn3/Grik2/Htr2a/Cacng7/Cacna1a/Cacnb4	21
GO:0072009	nephron epithelium development	BP	0.179	2.07e-08	8.38e-07	6.08	5.7e-07	Wnt6/Hoxd11/Nog/Npnt/Ptpro/Cd44/Hoxa11/Adamts16/Gpc3/Ednrb/Mef2c/Gli3/Tcf21/Agtr1a/Heyl/Ednra/Ptch1/Osr1/Dchs1/Aqp11/Fat4	21
GO:0050767	regulation of neurogenesis	BP	0.103	2.12e-08	8.51e-07	6.07	5.79e-07	Prtg/Ptprz1/Efnb3/Map2/Sema5a/Mdk/Kdr/Nog/Plxnb1/Ptprd/Igf1/Sema5b/Zeb2/Sema7a/Nrp1/Tert/Fn1/Dab1/Id4/Serpine2/Cxcl12/Tbc1d24/Obsl1/Gli3/Lrp2/Thy1/Plxnd1/Trpc6/Mme/Kit/Vegfc/Apoe/Heyl/Caprin2/Daam2/Sema3g/Nin/Bin1/Zcchc24/Epha7/Chodl/Nfatc4/Bhlhb9/Cux2/Syngap1/Sema6a/Ptn	47
GO:0071695	anatomical structure maturation	BP	0.12	2.22e-08	8.87e-07	6.05	6.03e-07	Epha8/Ihh/Pla2g10/Ryr1/Kdr/Spink1/Plxnb1/Igf1/Thbs3/Cspg4/Ednrb/Slc24a4/Lrrk2/Mmp2/Myo5a/Gdf11/Flvcr1/Calca/Plcb1/Rps6ka2/Cdh5/Pth1r/Dlg2/Cdkn1c/Nfasc/Enpp1/Kcnma1/Ednra/Adamts7/Lhx6/Tal1/Dchs1/Septin4/Xylt1/Fat4/Cacna1a	36
GO:0001649	osteoblast differentiation	BP	0.135	2.26e-08	8.93e-07	6.05	6.08e-07	Gli1/Ihh/Sfrp2/Wnt11/Nog/Igf1/Ddr2/Npnt/Fermt2/Areg/Mef2c/Id3/Id4/Prkd1/Gli3/Glis1/Nell1/Pth1r/Gdf10/Smoc1/Vegfc/Enpp1/Igf2/Rorb/Tnfaip6/Twist2/Rassf2/Ptch1/Lrp3/Gabbr1	30
GO:0006814	sodium ion transport	BP	0.129	2.39e-08	9.38e-07	6.03	6.38e-07	Nalcn/Hecw2/Slc6a2/Slc5a11/Slc13a5/Nos3/Slc8a1/Scn4b/Drd4/Scn1a/Fxyd5/Ednrb/Slc24a4/Slc9a7/Serpine2/Slc24a3/Slc8a3/Plcb1/Slc6a15/Scn2a/Maged2/Slc9a5/Ednra/Slc23a2/Osr1/Slc38a1/Pkd2/Scn3a/Atp2b4/Akt3/Atp1a2/Slc4a8	32
GO:0050870	positive regulation of T cell activation	BP	0.135	2.51e-08	9.77e-07	6.01	6.64e-07	Ihh/Efnb3/Lef1/Mdk/Cd83/Igf1/Pik3r6/Gli3/Tnfsf13b/Thy1/Cd1d1/Coro1a/Itgal/Il27ra/H2-Ab1/Havcr2/Sox12/H2-Ob/Igf2/Xcl1/Nckap1l/H2-Eb1/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il12rb1/Cav1/Il2rg	30
GO:0007229	integrin-mediated signaling pathway	BP	0.194	2.64e-08	1.02e-06	5.99	6.95e-07	Itga4/Sema7a/Nrp1/Fermt2/Itgb7/Fn1/Itga1/Thy1/Plpp3/Loxl3/Itgal/Itga7/Pcsk5/Ccn2/Fgr/Lat/Ptn/Itga8/Itgb4	19
GO:0048813	dendrite morphogenesis	BP	0.144	2.77e-08	1.06e-06	5.97	7.24e-07	Ptprz1/Hecw2/Ptprd/Nlgn1/Tet1/Nrp1/Lrrk2/Tbc1d24/Obsl1/Ppfia2/Dock10/Trpc6/Kif1a/Abi2/Nlgn3/Caprin2/Prex2/Sarm1/Nfatc4/Fyn/Bhlhb9/Dlg4/Cux2/Ngef/Ptn/Dact1/Cacna1a	27
GO:0001569	branching involved in blood vessel morphogenesis	BP	0.289	2.8e-08	1.07e-06	5.97	7.27e-07	Ihh/Sfrp2/Sema5a/Angpt1/Lef1/Mdk/Kdr/Nrp1/Tek/Cxcl12/Plxnd1/Ednra/Nfatc4	13
GO:0003205	cardiac chamber development	BP	0.14	3.05e-08	1.15e-06	5.94	7.85e-07	Col11a1/Stra6/Sfrp2/Wnt11/Nog/Tbx2/Nos3/Nrp1/Kif7/Foxf1/Mef2c/Tek/Ank2/Adamts1/Lrp2/Cpe/Plxnd1/Prdm1/Ccm2l/Aplnr/Cplane1/Tbx3/Heyl/Ednra/Myl3/Pcsk5/Heg1/Fzd2	28
GO:0007264	small GTPase mediated signal transduction	BP	0.104	3.07e-08	1.15e-06	5.94	7.85e-07	Igf1/Adra1a/Ccdc88a/Rasgrp3/Nrp1/Cdh2/Arl6/Garnl3/Dab1/Rasa3/Lpar4/Prkd1/Arhgef25/Cdh13/Rasgrp2/Arhgap25/Dock2/Sh2b2/Syde1/Dock10/Abi2/Sh3bp1/Apoe/Agtr1a/Rasip1/Eps8l1/Ednra/Pecam1/Adcyap1r1/Arap3/Rhobtb3/Kitl/Arrb1/Arl3/Heg1/Arhgap28/Dlc1/Net1/Arhgap31/Lat/Syngap1/Rab39b/Cdc42ep5/Arhgef9/Mapre2	45
GO:0051216	cartilage development	BP	0.136	3.26e-08	1.22e-06	5.91	8.29e-07	Col11a1/Ihh/Sfrp2/Mdk/Hoxd11/Nog/Pkdcc/Thbs3/Cbs/Hoxa11/Mef2c/Osr2/Stc1/Gli3/Pth1r/Wnt9a/Zeb1/Mgp/Enpp1/Hoxd3/Snai1/Adamts7/Smad9/Ltbp3/Bgn/Pkd1/Osr1/Ccn2/Bbs1	29
GO:0051145	smooth muscle cell differentiation	BP	0.212	3.41e-08	1.26e-06	5.9	8.6e-07	Tbx2/Npnt/Ednrb/Foxf1/Mef2c/Tshz3/Zeb1/Kit/Cth/Aplnr/Tbx3/Ednra/Nfatc4/Rbpms2/Efemp2/Sgcb/Itga8	17
GO:0002691	regulation of cellular extravasation	BP	0.283	3.75e-08	1.38e-06	5.86	9.38e-07	Mdk/Itga4/Chst2/Icam1/Cxcl12/Jam3/Plcb1/Thy1/Il27ra/Sele/Pecam1/Ptger3/St3gal4	13
GO:0099504	synaptic vesicle cycle	BP	0.132	3.77e-08	1.38e-06	5.86	9.38e-07	Syn2/Nlgn1/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Cdh2/Lrrk2/Pfn2/Tbc1d24/Ppfia2/Htr1b/Syde1/Cadps/Nlgn3/Syt7/Prrt2/Magi2/Htr2a/Bin1/Erc2/Ncs1/Pcdh17/Brsk1/Nrn1/Stx2/Slc4a8/Cacna1a/Cacnb4	30
GO:1903522	regulation of blood circulation	BP	0.124	3.81e-08	1.38e-06	5.86	9.41e-07	Cacna1c/Kcnd3/Adra1a/Nos3/Slc8a1/Scn4b/Ednrb/Cacna2d1/Mmp2/Icam1/Wdr35/Stc1/Hopx/Cacna1e/Edn3/Ank2/Calca/Cd38/Agtr1a/Gjc1/Ednra/Htr2a/Myl3/Bin1/Pde5a/Cacna1h/Ptger3/Slc4a3/Ccn2/Apln/Atp2b4/Atp1a2/Cav1	33
GO:0050863	regulation of T cell activation	BP	0.112	3.86e-08	1.39e-06	5.86	9.47e-07	Ihh/Efnb3/Lef1/Mdk/Cd83/Igf1/Cd44/Mapk8ip1/Pik3r6/Gli3/Tnfsf13b/Thy1/Zeb1/Prdm1/Cd1d1/Loxl3/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Havcr2/Sox12/H2-Ob/Igf2/Xcl1/Nckap1l/H2-Eb1/Pde5a/H2-Aa/Stat5b/Gimap5/Zap70/Dlg5/Gimap3/Lat/Il12rb1/Cav1/Il2rg	39
GO:0009612	response to mechanical stimulus	BP	0.146	3.92e-08	1.41e-06	5.85	9.56e-07	Col11a1/Stra6/Slc1a3/Mdk/Wnt11/Igf1/Nos3/Slc8a1/Scn1a/Mmp2/Grin2b/Serpine2/Cxcl12/Kit/Ednra/Htr2a/Cnn2/Pkd1/Fyn/Pkd2/Atp1a2/Habp4/Ptn/Pkdrej/Piezo2/Cav1	26
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.107	3.95e-08	1.41e-06	5.85	9.58e-07	Sfrp2/Lef1/Cd109/Kdr/Nog/Rnf165/Zeb2/Npnt/Fst/Fermt2/Gpc3/Btbd11/Gdf11/Zfp423/Lrp2/Gdf7/Cdh5/Pbld2/Zeb1/Gdf10/Tgif2/Cdkn1c/Tsku/Magi2/Emilin1/Spred3/Kcp/Smad9/Ltbp3/Tnfaip6/Hipk2/Nrros/Zfyve9/Cldn5/Arrb2/Neo1/Il17rd/Fstl1/Lats2/Cav1/Itga8/Tmprss6	42
GO:0010522	regulation of calcium ion transport into cytosol	BP	0.18	4.18e-08	1.47e-06	5.83	1e-06	Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Calca/Thy1/Coro1a/Aplnr/Agtr1a/Ednra/Adcyap1r1/Asph/Selenon/Fyn/Pkd2/Gstm7/Gimap5/Gimap3/Cav1	20
GO:0099175	regulation of postsynapse organization	BP	0.18	4.18e-08	1.47e-06	5.83	1e-06	Ptprd/Nlgn1/Cdh2/Lrrc4b/Lrrk2/Nptx1/Grin2b/Ppfia2/Kif1a/Abi2/Nlgn3/Dgkb/Apoe/Caprin2/Epha7/Lrfn2/Fyn/Bhlhb9/Cux2/Ngef	20
GO:0050931	pigment cell differentiation	BP	0.308	4.37e-08	1.53e-06	5.82	1.04e-06	Adamts20/Zeb2/Ednrb/Mef2c/Myo5a/Ap1m1/Edn3/Gli3/Kit/Enpp1/Kitl/Rab27a	12
GO:0060021	roof of mouth development	BP	0.188	4.4e-08	1.53e-06	5.82	1.04e-06	Lef1/Wnt11/Pkdcc/Tbx2/Mef2c/Osr2/Tshz1/Gdf11/Bbs7/Gli3/Tcf21/Jag2/Loxl3/Cplane1/Tbx3/Snai1/Asph/Osr1/Fzd2	19
GO:0045123	cellular extravasation	BP	0.207	5.02e-08	1.73e-06	5.76	1.18e-06	Mdk/Itga4/Chst2/Itgb7/Icam1/Podxl2/Cxcl12/Jam3/Itga1/Plcb1/Thy1/Itgal/Il27ra/Sele/Pecam1/Ptger3/St3gal4	17
GO:0071805	potassium ion transmembrane transport	BP	0.136	5.8e-08	1.99e-06	5.7	1.35e-06	Kcnk3/Kcnb2/Nalcn/Kcnj3/Slc1a3/Kcna6/Kcnd2/Kcnd3/Slc12a8/Slc24a4/Kcnq5/Slc9a7/Slc24a3/Edn3/Ank2/Kcnma1/Slc9a5/Kcnc4/Bin1/Kcnip3/Fhl1/Kcng4/Ptger3/Pkd2/Slc12a4/Atp1a2/Kcnq4/Cav1	28
GO:1901890	positive regulation of cell junction assembly	BP	0.169	5.93e-08	2.02e-06	5.69	1.37e-06	Kdr/Ptprd/St8sia2/Nlgn1/Nrp1/Fermt2/Lrrc4b/Col16a1/Tek/Adgrl1/Slitrk3/Thy1/Ppm1f/Nlgn3/Cldn5/Bhlhb9/Cux2/Nphp1/Dlg5/Cav1/Cldn1	21
GO:0001885	endothelial cell development	BP	0.216	6.63e-08	2.24e-06	5.65	1.53e-06	Ednrb/Icam1/Stc1/Plcb1/Cdh5/Msn/Ppp1r16b/Robo4/Ednra/Pecam1/Col15a1/Heg1/Arhgef26/Cldn5/Col18a1/Cldn1	16
GO:0009582	detection of abiotic stimulus	BP	0.162	6.78e-08	2.28e-06	5.64	1.55e-06	Col11a1/Sema5a/Igf1/Sema5b/Scn1a/Slc24a4/Ano1/Grin2b/Serpine2/Cxcl12/Calca/Kit/Grik2/Htr2a/Arrb1/Pkd1/Arrb2/Fyn/Pkd2/Pkdrej/Piezo2/Cacnb4	22
GO:0045766	positive regulation of angiogenesis	BP	0.142	6.94e-08	2.3e-06	5.64	1.56e-06	Cyp1b1/Hgf/Sfrp2/Sema5a/Mdk/Kdr/Ddah1/Nos3/Nrp1/Ets1/Tert/Prkd1/Tek/Cxcr3/Pik3r6/Cdh5/Aplnr/Jcad/Vegfc/Agtr1a/Emilin1/Tie1/Igf2/Hipk2/Akt3/Vash2	26
GO:1904018	positive regulation of vasculature development	BP	0.142	6.94e-08	2.3e-06	5.64	1.56e-06	Cyp1b1/Hgf/Sfrp2/Sema5a/Mdk/Kdr/Ddah1/Nos3/Nrp1/Ets1/Tert/Prkd1/Tek/Cxcr3/Pik3r6/Cdh5/Aplnr/Jcad/Vegfc/Agtr1a/Emilin1/Tie1/Igf2/Hipk2/Akt3/Vash2	26
GO:1990778	protein localization to cell periphery	BP	0.108	6.95e-08	2.3e-06	5.64	1.56e-06	Gpc6/Kcnb2/Ar/Pkdcc/Tub/Epb41l3/Ccdc88a/Stx1b/Gnai1/Cdh2/Efr3b/Arl6/Abi3/Nptx1/Myo5a/Gga2/Ank2/Rab34/Dlg2/Epha3/Lin7a/Ttc7b/Nptxr/Nfasc/Rilpl1/Magi2/Nsg1/Stac2/Arl3/Cacng7/Ptch1/Kcnip3/Dchs1/Tspan5/Dlg4/Atp2b4/Palm/Bbs1/Pid1/Nkd2	40
GO:0003002	regionalization	BP	0.106	7.26e-08	2.38e-06	5.62	1.62e-06	Gli1/Sfrp2/Hhip/Ar/Lef1/Wnt11/Hoxd10/Hoxd11/Nog/Zeb2/Hoxa11/Nrp1/Dzip1l/Gpc3/Hoxd9/Hoxa10/Foxf1/Mef2c/Hoxd8/Hoxd4/Tshz1/Gdf11/Gli3/Lrp2/Ift57/Lfng/Gpr161/Hoxd3/Tbx3/Heyl/Dync2h1/Ednra/Snai1/Pcsk5/Hoxa9/Hipk2/Ptch1/Nr2f1/Osr1/Ets2/Rab23	41
GO:0016079	synaptic vesicle exocytosis	BP	0.161	7.75e-08	2.52e-06	5.6	1.71e-06	Nlgn1/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Pfn2/Ppfia2/Htr1b/Syde1/Cadps/Syt7/Prrt2/Htr2a/Erc2/Ncs1/Nrn1/Stx2/Slc4a8/Cacna1a/Cacnb4	22
GO:0032412	regulation of ion transmembrane transporter activity	BP	0.12	7.78e-08	2.52e-06	5.6	1.71e-06	Hecw2/Nlgn1/Tcaf1/Scn4b/Drd4/Fxyd5/Cacna2d1/Mef2c/Myo5a/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Prrt1/Ednra/Stac2/Cacng7/Dysf/Fhl1/Asph/Selenon/Osr1/Rrad/Pkd2/Dlg4/Gstm7/Atp1a2/Gnb5/Abcb1a/Cav1/Cacna1a/Cacnb4	33
GO:0043270	positive regulation of ion transport	BP	0.112	7.82e-08	2.52e-06	5.6	1.71e-06	Grik1/Cacna1c/Pla2g10/Abat/Tcaf1/Scn4b/Drd4/Cacna2d1/Myo5a/Grin2b/Stc1/Cxcr3/Cxcl12/Edn3/Ank2/Plcb1/Thy1/Trpc6/Nlgn3/Aplnr/Cracr2a/Agtr1a/Ednra/Adcyap1r1/Stac2/Fhl1/Asph/Arrb2/Pkd2/Gstm7/Gimap5/Akt3/Gimap3/Abcb1a/Cav1/Gabbr1/Cacnb4	37
GO:0099068	postsynapse assembly	BP	0.324	8.95e-08	2.85e-06	5.55	1.94e-06	Gap43/Ptprd/Nlgn1/Cdh2/Lrrc4b/Nptx1/Slitrk3/Nlgn3/Nptxr/Magi2/Arhgef9	11
GO:0099560	synaptic membrane adhesion	BP	0.324	8.95e-08	2.85e-06	5.55	1.94e-06	Gpc6/Lrrc4c/Ptprd/Nlgn1/Lrrc4b/Slitrk3/Epha3/Sparcl1/Magi2/Pcdh17/Ntng1	11
GO:0003015	heart process	BP	0.124	9.86e-08	3.12e-06	5.51	2.12e-06	Sgcd/Cacna1c/Kcnd3/Adra1a/Nos3/Slc8a1/Scn4b/Scn1a/Ednrb/Cacna2d1/Stc1/Hopx/Cacna1e/Edn3/Ank2/Calca/Rps6ka2/Nox4/Gjc1/Ednra/Myl3/Bin1/Pde5a/Cacna1h/Slc4a3/Ccn2/Fyn/Apln/Atp2b4/Atp1a2/Cav1	31
GO:0045446	endothelial cell differentiation	BP	0.171	1.04e-07	3.27e-06	5.49	2.22e-06	Kdr/Ednrb/Icam1/Stc1/Plcb1/Cdh5/Zeb1/Msn/Ppp1r16b/Robo4/Tie1/Ednra/Pecam1/Col15a1/Heg1/Arhgef26/Cldn5/Fstl1/Col18a1/Cldn1	20
GO:0048562	embryonic organ morphogenesis	BP	0.111	1.07e-07	3.33e-06	5.48	2.27e-06	Gli1/Col11a1/Stra6/Ihh/Mmp16/Wnt11/Hoxd10/Hoxd11/Nog/Tbx2/Hoxa11/Hoxd9/Foxf1/Mef2c/Osr2/Hoxd4/Tshz1/Lrig3/Flvcr1/Gli3/Tcf21/Ift57/Wnt9a/Zeb1/Aplnr/Enpp1/Hoxd3/Tbx3/Ednra/Hoxa9/Twist2/Hipk2/Osr1/Pkd2/Fzd2/Kcnq4/Itga8	37
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	BP	0.314	1.26e-07	3.91e-06	5.41	2.66e-06	Pcdh18/Nlgn1/Cdh2/Cdh6/Cdh13/Pcdhgc3/Cdh10/Cdh5/Pcdh12/Cdh11/Dchs1	11
GO:0070997	neuron death	BP	0.1	1.32e-07	4.09e-06	5.39	2.78e-06	Ptprz1/Angpt1/Mdk/Dcc/Kdr/Agap2/Igf1/St8sia2/Ddr2/Nrp1/Tert/Bok/Lrrk2/Dpysl4/Mef2c/Grin2b/Pcdhgc3/Tbc1d24/Itga1/Scn2a/Coro1a/Il27ra/Grik2/Apoe/Rilpl1/Enpp1/Kcnma1/Cd200/Ndnf/Slc23a2/Arrb1/Hipk2/Epha7/Sarm1/Kcnip3/Nlrp1b/Nfatc4/Arrb2/Neo1/Fyn/Bhlhb9/Syngap1/Nes/Cacna1a	44
GO:0061326	renal tubule development	BP	0.176	1.34e-07	4.11e-06	5.39	2.8e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Mef2c/Gli3/Tcf21/Agtr1a/Heyl/Ptch1/Osr1/Dchs1/Aqp11/Pkd2/Fat4	19
GO:0043271	negative regulation of ion transport	BP	0.141	1.38e-07	4.21e-06	5.38	2.86e-06	Maob/Hecw2/Spink1/Abat/Nos3/Drd4/Myo5a/Icam1/Stc1/Serpine2/Calca/Htr1b/Htr2a/Bin1/Dysf/Osr1/Rrad/Ptger3/Pkd2/Gstm7/Atp1a2/Gnb5/Cav1/Gabbr1/Usp2	25
GO:0099003	vesicle-mediated transport in synapse	BP	0.122	1.42e-07	4.28e-06	5.37	2.91e-06	Syn2/Nlgn1/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Cdh2/Lrrk2/Pfn2/Tbc1d24/Ppfia2/Htr1b/Syde1/Cadps/Nlgn3/Syt7/Prrt2/Magi2/Htr2a/Nsg1/Bin1/Erc2/Ncs1/Pcdh17/Brsk1/Nrn1/Stx2/Slc4a8/Cacna1a/Cacnb4	31
GO:0001738	morphogenesis of a polarized epithelium	BP	0.193	1.49e-07	4.49e-06	5.35	3.06e-06	Sfrp2/Wnt11/Nkd1/Gpc3/Foxf1/Msn/Myo9a/Znrf3/Cplane1/Sh3bp1/Dchs1/Fzd2/Nphp1/Fat4/Dlg5/Brsk1/Dact1	17
GO:0042310	vasoconstriction	BP	0.174	1.56e-07	4.65e-06	5.33	3.16e-06	Cacna1c/Adra1a/Slc8a1/Ednrb/Mmp2/Icam1/Wdr35/Edn3/Htr1b/Cd38/Agtr1a/Ednra/Bdkrb2/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1	19
GO:0051926	negative regulation of calcium ion transport	BP	0.217	1.58e-07	4.66e-06	5.33	3.17e-06	Spink1/Nos3/Drd4/Icam1/Stc1/Calca/Bin1/Dysf/Rrad/Ptger3/Pkd2/Gstm7/Atp1a2/Gnb5/Usp2	15
GO:0051492	regulation of stress fiber assembly	BP	0.182	1.7e-07	5.01e-06	5.3	3.41e-06	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Ppm1e/Arhgap28/Dlc1/Ccn2	18
GO:0006813	potassium ion transport	BP	0.123	1.74e-07	5.09e-06	5.29	3.46e-06	Kcnk3/Kcnb2/Nalcn/Kcnj3/Slc1a3/Kcna6/Kcnd2/Kcnd3/Slc12a8/Nos3/Slc24a4/Kcnq5/Slc9a7/Slc24a3/Edn3/Ank2/Kcnma1/Slc9a5/Kcnc4/Htr2a/Bin1/Kcnip3/Fhl1/Kcng4/Ptger3/Pkd2/Slc12a4/Atp1a2/Kcnq4/Cav1	30
GO:0033627	cell adhesion mediated by integrin	BP	0.191	1.77e-07	5.11e-06	5.29	3.47e-06	Epha8/Cyp1b1/Itga4/Npnt/Itgb7/Col16a1/Icam1/Jam3/Itga1/Podxl/Plpp3/Itgal/Emilin1/Itga7/Nckap1l/Itga8/Itgb4	17
GO:0050805	negative regulation of synaptic transmission	BP	0.191	1.77e-07	5.11e-06	5.29	3.47e-06	Grik1/Grid2ip/Celf4/Drd4/Gnai1/Lrrk2/Myo5a/Shank2/Htr1b/Nlgn3/Sorcs2/Grik2/Prrt1/Cd38/Htr2a/Pcdh17/Gabbr1	17
GO:0061333	renal tubule morphogenesis	BP	0.191	1.77e-07	5.11e-06	5.29	3.47e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Mef2c/Gli3/Tcf21/Agtr1a/Ptch1/Osr1/Dchs1/Pkd2/Fat4	17
GO:0001823	mesonephros development	BP	0.173	1.82e-07	5.17e-06	5.29	3.52e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Osr2/Gdf11/Gli3/Tcf21/Tshz3/Agtr1a/Smad9/Ptch1/Osr1/Dchs1/Fat4	19
GO:0022898	regulation of transmembrane transporter activity	BP	0.116	1.82e-07	5.17e-06	5.29	3.52e-06	Hecw2/Nlgn1/Tcaf1/Scn4b/Drd4/Fxyd5/Cacna2d1/Mef2c/Myo5a/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Prrt1/Ednra/Stac2/Cacng7/Dysf/Fhl1/Asph/Selenon/Osr1/Rrad/Pkd2/Dlg4/Gstm7/Atp1a2/Gnb5/Abcb1a/Cav1/Cacna1a/Cacnb4	33
GO:0032409	regulation of transporter activity	BP	0.114	1.85e-07	5.2e-06	5.28	3.54e-06	Hecw2/Slc5a11/Nlgn1/Tcaf1/Scn4b/Drd4/Fxyd5/Cacna2d1/Mef2c/Myo5a/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Prrt1/Ednra/Stac2/Cacng7/Dysf/Fhl1/Asph/Selenon/Osr1/Rrad/Pkd2/Dlg4/Gstm7/Atp1a2/Gnb5/Abcb1a/Cav1/Cacna1a/Cacnb4	34
GO:0099084	postsynaptic specialization organization	BP	0.273	1.94e-07	5.41e-06	5.27	3.68e-06	Gap43/Ptprd/Nlgn1/Cdh2/Lrrc4b/Nptx1/Shank2/Slitrk3/Nlgn3/Nptxr/Syngap1/Arhgef9	12
GO:0006887	exocytosis	BP	0.101	1.94e-07	5.41e-06	5.27	3.68e-06	Syn2/Cacna1c/Nlgn1/Syt13/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Foxf1/Myo5a/Pfn2/Mical1/Ppfia2/Exoc3l/Htr1b/Syde1/Cadps/Coro1a/Kit/Lin7a/Syt7/Prrt2/Htr2a/Nckap1l/Erc2/Ncs1/Myo1f/Cd84/Cacna1h/Septin4/Fgr/Lat/Rab27a/Clnk/Nrn1/Stx2/Slc4a8/Cacna1a/Nkd2/Cacnb4	42
GO:0007416	synapse assembly	BP	0.135	2.04e-07	5.66e-06	5.25	3.85e-06	Gpc6/Gap43/Sdk2/Plxnb1/Ptprd/St8sia2/Nlgn1/Cdh2/Lrrc4b/Nptx1/Mef2c/Shank2/Obsl1/Adgrl1/Slitrk3/Plxnd1/Nlgn3/Nptxr/Magi2/Epha7/Pcdh17/Bhlhb9/Cux2/Dlg5/Arhgef9/Cacna1a	26
GO:0008344	adult locomotory behavior	BP	0.171	2.11e-07	5.75e-06	5.24	3.91e-06	Efnb3/Cacna1c/Hoxd10/Drd4/Scn1a/Hoxd9/Ccnd2/Dab1/Cxcl12/Shank2/Glrb/Enpp1/Kcnma1/Prex2/Hipk2/Arrb2/Atp1a2/Cacna1a/Cacnb4	19
GO:0110020	regulation of actomyosin structure organization	BP	0.171	2.11e-07	5.75e-06	5.24	3.91e-06	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Mef2c/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Ppm1e/Arhgap28/Dlc1/Ccn2	19
GO:0051928	positive regulation of calcium ion transport	BP	0.152	2.17e-07	5.89e-06	5.23	4.01e-06	Cacna1c/Cacna2d1/Stc1/Cxcr3/Cxcl12/Ank2/Thy1/Trpc6/Aplnr/Cracr2a/Agtr1a/Ednra/Adcyap1r1/Stac2/Asph/Arrb2/Pkd2/Gstm7/Gimap5/Gimap3/Cav1/Cacnb4	22
GO:0042733	embryonic digit morphogenesis	BP	0.211	2.35e-07	6.33e-06	5.2	4.3e-06	Ihh/Sfrp2/Hoxd11/Nog/Tbx2/Hoxa11/Osr2/Flvcr1/Gli3/Cplane1/Tbx3/Tmem231/Osr1/Ttbk2/Rab23	15
GO:2000351	regulation of endothelial cell apoptotic process	BP	0.245	2.35e-07	6.33e-06	5.2	4.3e-06	Sema5a/Angpt1/Itga4/Kdr/Tert/Icam1/Tek/Cdh5/Cd248/Ecscr/Ndnf/Angptl4/Col18a1	13
GO:0048706	embryonic skeletal system development	BP	0.151	2.45e-07	6.57e-06	5.18	4.47e-06	Col11a1/Ihh/Mmp16/Hoxd10/Hoxd11/Nog/Hoxa11/Hoxd9/Mef2c/Osr2/Hoxd4/Flvcr1/Gli3/Wnt9a/Zeb1/Hoxd3/Ednra/Pcsk5/Hoxa9/Twist2/Osr1/Xylt1	22
GO:0043010	camera-type eye development	BP	0.104	2.6e-07	6.91e-06	5.16	4.7e-06	Ndp/Stra6/Ihh/Cyp1b1/Sdk2/Nhs/Cacna1c/Kdr/Tbx2/Tub/Rcn1/Zeb2/Celf4/Lamc3/Nrp1/Arl6/Tenm3/Osr2/Gdf11/Obsl1/Gli3/Thy1/Zeb1/Tgif2/Ptprm/Abi2/Rp1/Cdkn1c/Tsku/Arhgef15/Spred3/Rorb/Lpcat1/Twist2/Hipk2/Tmem231/Fat3/Nphp1/Ptn	39
GO:0072080	nephron tubule development	BP	0.176	2.72e-07	7.22e-06	5.14	4.91e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Mef2c/Gli3/Tcf21/Agtr1a/Heyl/Ptch1/Osr1/Dchs1/Aqp11/Fat4	18
GO:0060079	excitatory postsynaptic potential	BP	0.185	2.93e-07	7.7e-06	5.11	5.24e-06	Grik1/Begain/Nlgn1/Celf4/Drd4/Stx1b/Lrrk2/Mef2c/Grin2b/Tbc1d24/Slc8a3/Slc29a1/Nlgn3/Grik2/Mpp2/Dlg4/Cux2	17
GO:0030111	regulation of Wnt signaling pathway	BP	0.11	2.93e-07	7.7e-06	5.11	5.24e-06	Gli1/Sfrp2/Sema5a/Lef1/Mdk/Apcdd1/Wnt11/Nog/Zeb2/Ptpro/Nkd1/Tert/Cdh2/Gpc3/Lrrk2/Tmem237/Rbms3/Gprc5b/Gli3/Peg12/Plpp3/Dkk3/Znrf3/Tsku/Apoe/Caprin2/Daam2/Prickle1/Tle1/Nfatc4/Lats2/Adgra2/Cav1/Dact1/Nkd2	35
GO:0008016	regulation of heart contraction	BP	0.132	3.07e-07	8.03e-06	5.1	5.46e-06	Cacna1c/Kcnd3/Adra1a/Nos3/Slc8a1/Scn4b/Ednrb/Cacna2d1/Stc1/Hopx/Cacna1e/Edn3/Ank2/Calca/Gjc1/Ednra/Myl3/Bin1/Pde5a/Cacna1h/Slc4a3/Ccn2/Apln/Atp2b4/Atp1a2/Cav1	26
GO:0021510	spinal cord development	BP	0.175	3.17e-07	8.2e-06	5.09	5.58e-06	Vit/Hoxd10/Dcc/Nog/Dab1/Gdf11/Gli3/Gdf7/Loxl3/Phgdh/Enpp1/Sox12/Dync2h1/Daam2/Tal1/Ptch1/Rab23/Cacna1a	18
GO:0099565	chemical synaptic transmission, postsynaptic	BP	0.175	3.17e-07	8.2e-06	5.09	5.58e-06	Grik1/Begain/Nlgn1/Abat/Celf4/Drd4/Stx1b/Lrrk2/Mef2c/Grin2b/Tbc1d24/Slc8a3/Slc29a1/Nlgn3/Grik2/Mpp2/Dlg4/Cux2	18
GO:1901214	regulation of neuron death	BP	0.102	3.24e-07	8.33e-06	5.08	5.67e-06	Ptprz1/Angpt1/Mdk/Dcc/Kdr/Agap2/Igf1/St8sia2/Ddr2/Nrp1/Tert/Bok/Lrrk2/Mef2c/Grin2b/Pcdhgc3/Tbc1d24/Itga1/Coro1a/Il27ra/Grik2/Apoe/Rilpl1/Kcnma1/Cd200/Ndnf/Slc23a2/Arrb1/Hipk2/Epha7/Sarm1/Kcnip3/Nfatc4/Arrb2/Neo1/Fyn/Bhlhb9/Syngap1/Nes/Cacna1a	40
GO:1903305	regulation of regulated secretory pathway	BP	0.135	3.28e-07	8.4e-06	5.08	5.71e-06	Nlgn1/Syt13/Adra1a/Rims3/Drd4/P2rx2/Lrrk2/Foxf1/Pfn2/Mical1/Ppfia2/Htr1b/Cadps/Syt7/Htr2a/Nckap1l/Ncs1/Cd84/Cacna1h/Fgr/Rab27a/Nrn1/Slc4a8/Cacna1a/Cacnb4	25
GO:0035136	forelimb morphogenesis	BP	0.261	3.3e-07	8.43e-06	5.07	5.73e-06	Cacna1c/Hoxd10/Hoxd11/Rnf165/Hoxa11/Hoxd9/Osr2/Wnt9a/Enpp1/Tbx3/Hoxa9/Osr1	12
GO:0010720	positive regulation of cell development	BP	0.103	3.41e-07	8.65e-06	5.06	5.89e-06	Ptprz1/Sema5a/Mdk/Hoxd11/Kdr/Nog/Plxnb1/Ptprd/Igf1/Zeb2/Sema7a/Hoxa11/Nrp1/Fermt2/Fn1/Serpine2/Cxcl12/Has2/Tbc1d24/Obsl1/Gli3/Lrp2/Cdh5/Plxnd1/Mme/Kit/Vegfc/Apoe/Caprin2/Nin/Bin1/Chodl/Pde5a/Cldn5/Net1/Bhlhb9/Cux2/Abcb1a/Ptn	39
GO:0043535	regulation of blood vessel endothelial cell migration	BP	0.183	3.44e-07	8.65e-06	5.06	5.89e-06	Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Mef2c/Prkd1/Vash1/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Hdac9/Atp2b4/Akt3	17
GO:1904035	regulation of epithelial cell apoptotic process	BP	0.183	3.44e-07	8.65e-06	5.06	5.89e-06	Sema5a/Angpt1/Mdk/Itga4/Kdr/Igf1/Tert/Bok/Icam1/Tek/Cdh5/Cd248/Ecscr/Ndnf/Arrb2/Angptl4/Col18a1	17
GO:0007613	memory	BP	0.143	3.52e-07	8.82e-06	5.05	6e-06	Mdk/Nog/Cyp7b1/Igf1/Aph1b/Drd4/Ccnd2/Chst10/Grin2b/B4galt2/Shank2/Slc8a3/Plcb1/Eif2ak4/Scn2a/Apoe/Igf2/Htr2a/Pde5a/Nfatc4/Cux2/Ptn/Itga8	23
GO:0060047	heart contraction	BP	0.122	3.67e-07	9.13e-06	5.04	6.21e-06	Sgcd/Cacna1c/Kcnd3/Adra1a/Nos3/Slc8a1/Scn4b/Scn1a/Ednrb/Cacna2d1/Stc1/Hopx/Cacna1e/Edn3/Ank2/Calca/Rps6ka2/Gjc1/Ednra/Myl3/Bin1/Pde5a/Cacna1h/Slc4a3/Ccn2/Apln/Atp2b4/Atp1a2/Cav1	29
GO:0050866	negative regulation of cell activation	BP	0.124	3.76e-07	9.31e-06	5.03	6.34e-06	Ihh/Mdk/Abat/Cd44/Foxf1/Serpine2/Gli3/Flt3/Prdm1/Loxl3/Btla/H2-Ab1/Apoe/Havcr2/Emilin1/Cd200/Nckap1l/Pde5a/Cd84/Ptger3/Fgr/H2-Aa/Gimap5/Dlg5/Gimap3/Clnk/Cygb/Nr1h3	28
GO:0035725	sodium ion transmembrane transport	BP	0.147	3.96e-07	9.78e-06	5.01	6.66e-06	Nalcn/Hecw2/Slc6a2/Slc8a1/Scn4b/Drd4/Scn1a/Fxyd5/Slc24a4/Slc9a7/Slc24a3/Slc8a3/Plcb1/Slc6a15/Scn2a/Slc9a5/Osr1/Pkd2/Scn3a/Atp2b4/Atp1a2/Slc4a8	22
GO:1903510	mucopolysaccharide metabolic process	BP	0.203	4.16e-07	1.02e-05	4.99	6.95e-06	Angpt1/Cd44/Spock2/Ednrb/Has2/Egflam/Mamdc2/Chst1/Ednra/Ndnf/Tnfaip6/Bgn/Xylt1/Dse/Habp4	15
GO:0030038	contractile actin filament bundle assembly	BP	0.164	4.29e-07	1.04e-05	4.98	7.1e-06	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Ppm1e/Arrb1/Arhgap28/Dlc1/Ccn2	19
GO:0043149	stress fiber assembly	BP	0.164	4.29e-07	1.04e-05	4.98	7.1e-06	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Ppm1e/Arrb1/Arhgap28/Dlc1/Ccn2	19
GO:0061448	connective tissue development	BP	0.112	4.38e-07	1.06e-05	4.97	7.23e-06	Col11a1/Ihh/Sfrp2/Mdk/Hoxd11/Nog/Igf1/Pkdcc/Thbs3/Cbs/Hoxa11/Mef2c/Osr2/Stc1/Id4/Gli3/Gdf7/Pth1r/Wnt9a/Zeb1/Mgp/Selenom/Enpp1/Hoxd3/Snai1/Adamts7/Smad9/Ltbp3/Bgn/Pkd1/Osr1/Ccn2/Bbs1	33
GO:0072577	endothelial cell apoptotic process	BP	0.232	4.69e-07	1.13e-05	4.95	7.7e-06	Sema5a/Angpt1/Itga4/Kdr/Tert/Icam1/Tek/Cdh5/Cd248/Ecscr/Ndnf/Angptl4/Col18a1	13
GO:0010632	regulation of epithelial cell migration	BP	0.12	4.78e-07	1.15e-05	4.94	7.79e-06	Sema5a/Angpt1/Kdr/Igf1/Evl/Nos3/Nrp1/Ets1/Mef2c/Pfn2/Stc1/Prkd1/Tek/Has2/Vash1/Plpp3/Ptprm/Ppm1f/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Hdac9/Atp2b4/Akt3/Arsb/Adgra2/Mapre2	29
GO:0007263	nitric oxide mediated signal transduction	BP	0.36	4.79e-07	1.15e-05	4.94	7.79e-06	Spink1/Nos3/Cbs/Gucy1a2/Gucy1a1/Apoe/Ndnf/Pde5a/Atp2b4	9
GO:0072171	mesonephric tubule morphogenesis	BP	0.2	4.99e-07	1.18e-05	4.93	8.03e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gli3/Tcf21/Agtr1a/Ptch1/Osr1/Dchs1/Fat4	15
GO:0051966	regulation of synaptic transmission, glutamatergic	BP	0.188	5e-07	1.18e-05	4.93	8.03e-06	Gria4/Grik1/Nlgn1/Cdh2/Lrrk2/Mef2c/Myo5a/Grin2b/Serpine2/Shank2/Htr1b/Tshz3/Nlgn3/Grik2/Htr2a/Cacng7	16
GO:0045216	cell-cell junction organization	BP	0.125	5.52e-07	1.3e-05	4.89	8.82e-06	Wnt11/Epb41l3/Ptpro/Mpdz/Fermt2/Cdh2/Cdh6/Jam3/Cldn8/Cdh10/Cdh5/Abi2/Aplnr/Esam/Nfasc/Cdh11/Gjc1/Pecam1/Snai1/Heg1/Svep1/Dchs1/Cldn5/Nphp1/Dlg5/Cav1/Cldn1	27
GO:0060078	regulation of postsynaptic membrane potential	BP	0.161	5.63e-07	1.32e-05	4.88	8.96e-06	Grik1/Begain/Nlgn1/Abat/Celf4/Drd4/Stx1b/Lrrk2/Mef2c/Grin2b/Tbc1d24/Slc8a3/Gabra4/Slc29a1/Nlgn3/Grik2/Mpp2/Dlg4/Cux2	19
GO:0001657	ureteric bud development	BP	0.168	5.71e-07	1.32e-05	4.88	8.96e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gdf11/Gli3/Tcf21/Tshz3/Agtr1a/Smad9/Ptch1/Osr1/Dchs1/Fat4	18
GO:0072163	mesonephric epithelium development	BP	0.168	5.71e-07	1.32e-05	4.88	8.96e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gdf11/Gli3/Tcf21/Tshz3/Agtr1a/Smad9/Ptch1/Osr1/Dchs1/Fat4	18
GO:0072164	mesonephric tubule development	BP	0.168	5.71e-07	1.32e-05	4.88	8.96e-06	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gdf11/Gli3/Tcf21/Tshz3/Agtr1a/Smad9/Ptch1/Osr1/Dchs1/Fat4	18
GO:0048872	homeostasis of number of cells	BP	0.102	6.17e-07	1.42e-05	4.85	9.64e-06	Tex15/Pla2g10/Col14a1/Gprasp2/Emcn/Crispld1/Nos3/P4htm/Cd44/Hcls1/Ets1/Cdh2/Mef2c/Jam3/Flvcr1/Plcb1/Myct1/Sh2b2/Flt3/Tnfsf13b/Dock10/Coro1a/Kit/Armcx1/Heph/Enpp1/Nckap1l/Tal1/Zfp251/Kitl/Rassf2/Septin4/Stat5b/Gimap5/Akt3/Gimap3/Lat/Fstl1	38
GO:0009101	glycoprotein biosynthetic process	BP	0.114	6.48e-07	1.48e-05	4.83	1.01e-05	St6gal2/Itm2a/Igf1/St8sia2/St8sia4/Gxylt2/Tet1/Uggt2/Chst10/Soat1/Tmtc1/B3galnt1/Fut10/Plcb1/Galnt16/St6galnac4/St3gal2/Eogt/Ggta1/St8sia6/Galntl6/Poglut2/Aqp11/Mgat3/B3gnt5/Xylt1/Dse/St6galnac6/St3gal4/Large1/Alg14	31
GO:0001658	branching involved in ureteric bud morphogenesis	BP	0.209	6.81e-07	1.55e-05	4.81	1.05e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gli3/Tcf21/Agtr1a/Ptch1/Dchs1/Fat4	14
GO:0030178	negative regulation of Wnt signaling pathway	BP	0.138	6.83e-07	1.55e-05	4.81	1.05e-05	Gli1/Sfrp2/Mdk/Apcdd1/Wnt11/Nog/Ptpro/Nkd1/Cdh2/Gpc3/Rbms3/Gli3/Dkk3/Znrf3/Tsku/Apoe/Prickle1/Tle1/Nfatc4/Lats2/Cav1/Dact1/Nkd2	23
GO:0051962	positive regulation of nervous system development	BP	0.103	6.95e-07	1.57e-05	4.8	1.07e-05	Ptprz1/Sema5a/Mdk/Kdr/Nog/Plxnb1/Ptprd/Igf1/St8sia2/Nlgn1/Zeb2/Sema7a/Nrp1/Lrrc4b/Fn1/Serpine2/Cxcl12/Tbc1d24/Obsl1/Adgrl1/Gli3/Lrp2/Slitrk3/Plxnd1/Mme/Kit/Nlgn3/Vegfc/Apoe/Caprin2/Nin/Bin1/Chodl/Bhlhb9/Cux2/Dlg5/Ptn	37
GO:0060976	coronary vasculature development	BP	0.195	7.14e-07	1.61e-05	4.79	1.09e-05	Angpt1/Sgcd/Nrp1/Kif7/Gpc3/Lrp2/Plxnd1/Prdm1/Aplnr/Cplane1/Dync2h1/Prickle1/Pcsk5/Apln/Prokr1	15
GO:0043087	regulation of GTPase activity	BP	0.104	7.29e-07	1.63e-05	4.79	1.11e-05	Wnt11/Plxnb1/Rgs6/Rgs16/Rasgrp3/Fermt2/Garnl3/Lrrk2/Rasa3/Arhgap45/Icam1/Rasgrp2/Arhgap25/Thy1/Plxnd1/Dock10/Epha3/Myo9a/Sh3bp1/Arhgef15/Arhgap6/Rasip1/Pecam1/Xcl1/Arap3/Bin1/Arrb1/Arhgef26/Net1/Arrb2/Fgd1/Gnb5/Syngap1/Ngef/Arhgap15/Mapre2	36
GO:0033674	positive regulation of kinase activity	BP	0.0966	7.31e-07	1.63e-05	4.79	1.11e-05	Epha8/Angpt1/Kdr/Agap2/Igf1/Ddr2/Zeb2/Adra1a/Ccdc88a/Drd4/Fermt2/Areg/Ccnd2/Dab1/Lrrk2/Tek/Edn3/Gprc5b/Pik3r6/Calca/Flt3/Kit/Epha3/Mmd/Vegfc/Nox4/Agtr1a/Tie1/Htr2a/Kitl/Pkd1/Epha7/Rassf2/Pde5a/Arrb2/Pkd2/Dlg4/Fgr/Atp2b4/Lat/Acsl1/C1qtnf9	42
GO:0048704	embryonic skeletal system morphogenesis	BP	0.165	7.57e-07	1.68e-05	4.77	1.15e-05	Col11a1/Mmp16/Hoxd10/Hoxd11/Nog/Hoxa11/Hoxd9/Mef2c/Osr2/Hoxd4/Flvcr1/Gli3/Wnt9a/Zeb1/Hoxd3/Hoxa9/Twist2/Osr1	18
GO:0008217	regulation of blood pressure	BP	0.123	7.95e-07	1.76e-05	4.75	1.2e-05	Ar/Cacna1c/Kdr/Ddah1/Adra1a/Abat/Nos3/Ptpro/Npr3/P2rx2/Adamts16/Ednrb/Enpep/Edn3/Calca/Rps6ka2/Postn/Gucy1a1/Vegfc/Agtr1a/Emilin1/Ednra/Bdkrb2/Trhde/Apln/Atp1a2/Lvrn	27
GO:1901215	negative regulation of neuron death	BP	0.115	8.16e-07	1.8e-05	4.75	1.22e-05	Ptprz1/Angpt1/Mdk/Kdr/Agap2/Igf1/Nrp1/Tert/Bok/Lrrk2/Mef2c/Pcdhgc3/Tbc1d24/Coro1a/Il27ra/Grik2/Apoe/Cd200/Ndnf/Slc23a2/Arrb1/Hipk2/Nfatc4/Arrb2/Neo1/Fyn/Bhlhb9/Syngap1/Nes/Cacna1a	30
GO:1902414	protein localization to cell junction	BP	0.157	8.37e-07	1.83e-05	4.74	1.25e-05	Gpc6/Nlgn1/Stx1b/Fermt2/Nptx1/Jam3/Slitrk3/Cdh5/Dlg2/Nlgn3/Nptxr/Magi2/Pecam1/Nsg1/Cacng7/Heg1/Dlg4/Dlg5/Abcb1a	19
GO:1904019	epithelial cell apoptotic process	BP	0.157	8.37e-07	1.83e-05	4.74	1.25e-05	Sema5a/Angpt1/Mdk/Itga4/Kdr/Igf1/Tert/Bok/Icam1/Tek/Cdh5/Jag2/Cd248/Ecscr/Ednra/Ndnf/Arrb2/Angptl4/Col18a1	19
GO:0042692	muscle cell differentiation	BP	0.0959	8.76e-07	1.9e-05	4.72	1.29e-05	AW551984/Sgcd/Col14a1/Ryr1/Igf1/Tbx2/Adra1a/Npnt/Slc8a1/P2rx2/Tmod2/Cdh2/Ednrb/Foxf1/Mef2c/Cxcl12/Hopx/Ank2/Tshz3/Zeb1/Kit/Cth/Aplnr/Nox4/Tbx3/Ednra/Igf2/Bin1/Hdac9/Dysf/Flnc/Selenon/Nfatc4/Arrb2/Neo1/Pi16/Rbpms2/Efemp2/Sgcb/Itga8/Plekho1/Cacnb4	42
GO:0022612	gland morphogenesis	BP	0.14	8.79e-07	1.9e-05	4.72	1.29e-05	Gli1/Hgf/Ar/Mdk/Nog/Cyp7b1/Igf1/Tbx2/Cd44/Nrp1/Areg/Mmp2/Id4/Gli3/Gdf7/Plxnd1/Msn/Tbx3/Ptch1/Ptn/Cav1/Edar	22
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	BP	0.24	8.81e-07	1.9e-05	4.72	1.29e-05	Hmcn1/Mcam/Itga4/Ptprd/Nlgn1/Cdh2/Tenm3/Adgrl1/Itgal/Sele/Dchs1/Fat4	12
GO:0003158	endothelium development	BP	0.15	8.81e-07	1.9e-05	4.72	1.29e-05	Kdr/Ednrb/Icam1/Stc1/Plcb1/Cdh5/Zeb1/Msn/Ppp1r16b/Robo4/Tie1/Ednra/Pecam1/Col15a1/Heg1/Arhgef26/Cldn5/Fstl1/Col18a1/Cldn1	20
GO:0090596	sensory organ morphogenesis	BP	0.107	9.07e-07	1.94e-05	4.71	1.32e-05	Col11a1/Stra6/Ihh/Sdk2/Kdr/Nog/Tbx2/Arl6/Tenm3/Osr2/Tshz1/Lrig3/Gdf11/Obsl1/Gli3/Thy1/Zeb1/Prdm1/Ptprm/Abi2/Rp1/Tsku/Enpp1/Tbx3/Ednra/Rorb/Col5a2/Hipk2/Osr1/Fzd2/Fat3/Ptn/Kcnq4/Itga8	34
GO:0046928	regulation of neurotransmitter secretion	BP	0.156	9.52e-07	2.03e-05	4.69	1.38e-05	Nlgn1/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Htr1b/Kcnc4/Htr2a/Ncs1/Nrn1/Slc4a8/Cacna1a/Cacnb4	19
GO:0051282	regulation of sequestering of calcium ion	BP	0.156	9.52e-07	2.03e-05	4.69	1.38e-05	Ryr1/Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Xcl1/Htr2a/Asph/Ryr3/Selenon/Xcr1/Pkd2/Slc25a23/Gstm7	19
GO:1901019	regulation of calcium ion transmembrane transporter activity	BP	0.18	9.57e-07	2.03e-05	4.69	1.38e-05	Drd4/Cacna2d1/Myo5a/Ank2/Cracr2a/Stac2/Dysf/Asph/Selenon/Rrad/Pkd2/Gstm7/Atp1a2/Gnb5/Cacna1a/Cacnb4	16
GO:1902905	positive regulation of supramolecular fiber organization	BP	0.131	9.72e-07	2.05e-05	4.69	1.39e-05	Sema5a/Wnt11/Evl/Ccdc88a/Nrp1/Fermt2/Wasf3/Pfn2/Icam1/Abi2/Ppm1f/Limch1/Nox4/Arhgef15/Ppm1e/Scin/Nckap1l/Slain1/Nin/Bin1/Ccn2/Efemp2/Cdc42ep5/Cav1	24
GO:0045667	regulation of osteoblast differentiation	BP	0.139	9.81e-07	2.06e-05	4.69	1.4e-05	Gli1/Sfrp2/Nog/Igf1/Ddr2/Npnt/Fermt2/Areg/Mef2c/Id3/Prkd1/Gli3/Nell1/Gdf10/Smoc1/Vegfc/Rorb/Tnfaip6/Twist2/Rassf2/Ptch1/Lrp3	22
GO:0090090	negative regulation of canonical Wnt signaling pathway	BP	0.149	9.95e-07	2.08e-05	4.68	1.42e-05	Gli1/Sfrp2/Mdk/Wnt11/Nog/Ptpro/Nkd1/Cdh2/Gpc3/Rbms3/Gli3/Dkk3/Znrf3/Apoe/Prickle1/Tle1/Lats2/Cav1/Dact1/Nkd2	20
GO:0014821	phasic smooth muscle contraction	BP	0.333	1.02e-06	2.12e-05	4.67	1.44e-05	Tbx2/P2rx2/Ednrb/Edn3/Tshz3/Kit/Kcnma1/Tbx3/Ptger3	9
GO:0001933	negative regulation of protein phosphorylation	BP	0.102	1.17e-06	2.44e-05	4.61	1.66e-05	Hgf/Sfrp2/Angpt1/Cd109/Spink1/Nog/Igf1/Ptpro/Slc8a1/Lrrk2/Mical1/Mapk8ip1/Slc8a3/Pkia/Thy1/Plpp3/Ppm1f/Cdkn1c/Prr5l/Apoe/Enpp1/Ppef2/Rasip1/Emilin1/Pecam1/Ppm1e/Bdkrb2/Pkib/Arrb1/Heg1/Rassf2/Arrb2/Lats2/Smpd1/Cav1/Pid1	36
GO:0050770	regulation of axonogenesis	BP	0.13	1.18e-06	2.45e-05	4.61	1.67e-05	Efnb3/Map2/Sema5a/Lrrc4c/Plxnb1/Sema5b/Zeb2/Sema7a/Nrp1/Cdh2/Fn1/Dab1/Cxcl12/Thy1/Plxnd1/Apoe/Sema3g/Nin/Epha7/Chodl/Brsk1/Syngap1/Sema6a/Cacna1a	24
GO:0051208	sequestering of calcium ion	BP	0.153	1.23e-06	2.53e-05	4.6	1.72e-05	Ryr1/Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Xcl1/Htr2a/Asph/Ryr3/Selenon/Xcr1/Pkd2/Slc25a23/Gstm7	19
GO:0010976	positive regulation of neuron projection development	BP	0.12	1.24e-06	2.54e-05	4.6	1.73e-05	Ptprz1/Hgf/Acsl6/Fez1/Mdk/Dcc/Lrrc7/Tenm3/Serpine2/Prkd1/Gprc5b/Adamts1/Serpini1/Epha3/Apoe/Magi2/Caprin2/Ndnf/P3h1/Fyn/Bhlhb9/Cux2/Dpysl3/Arsb/Ptn/Gpc2/Cpeb1	27
GO:0045880	positive regulation of smoothened signaling pathway	BP	0.256	1.27e-06	2.59e-05	4.59	1.76e-05	Gli1/Ihh/Evc/Kif7/Gpc3/Cibar1/Armc9/Rab34/Wnt9a/Dync2h1/Dlg5	11
GO:0060560	developmental growth involved in morphogenesis	BP	0.11	1.31e-06	2.66e-05	4.57	1.81e-05	Sfrp2/Map2/Sema5a/Wnt11/Itga4/St8sia2/Tbx2/Sema5b/Zeb2/Cpne5/Nkd1/Sema7a/Nrp1/Areg/Fn1/Cxcl12/Edn3/Eif2ak4/Postn/Ndn/Nlgn3/Apoe/Ednra/Sema3g/Slc23a2/Nin/Epha7/Cacng7/Sema6a/Nrn1/Cyfip2	31
GO:0031032	actomyosin structure organization	BP	0.122	1.4e-06	2.84e-05	4.55	1.93e-05	Kank4/Wnt11/Frmd3/Evl/Epb41l3/Phldb2/Ccdc88a/Nrp1/Fermt2/Tmod2/Mef2c/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Ppm1e/Cnn2/Arrb1/Flnc/Cnn3/Arhgap28/Dlc1/Ccn2	26
GO:0048844	artery morphogenesis	BP	0.185	1.41e-06	2.84e-05	4.55	1.93e-05	Apob/Stra6/Mdk/Wnt11/Nog/Tbx2/Nrp1/Foxf1/Fkbp10/Lrp2/Prdm1/Apoe/Ednra/Akt3/Efemp2	15
GO:0010594	regulation of endothelial cell migration	BP	0.132	1.41e-06	2.85e-05	4.55	1.94e-05	Sema5a/Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Mef2c/Stc1/Prkd1/Tek/Vash1/Plpp3/Ptprm/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Hdac9/Atp2b4/Akt3/Adgra2	23
GO:0043931	ossification involved in bone maturation	BP	0.321	1.44e-06	2.89e-05	4.54	1.96e-05	Ryr1/Plxnb1/Igf1/Thbs3/Enpp1/Adamts7/Dchs1/Xylt1/Fat4	9
GO:0098698	postsynaptic specialization assembly	BP	0.321	1.44e-06	2.89e-05	4.54	1.96e-05	Gap43/Ptprd/Nlgn1/Lrrc4b/Nptx1/Slitrk3/Nlgn3/Nptxr/Arhgef9	9
GO:0002685	regulation of leukocyte migration	BP	0.119	1.47e-06	2.92e-05	4.53	1.99e-05	Mdk/Itga4/Chst2/Icam1/Cxcr3/Cxcl12/Jam3/Edn3/Plcb1/Thy1/Msn/Il27ra/Vegfc/Sele/Emilin1/Cd200/Ednra/Pecam1/Xcl1/Nckap1l/Kitl/Tnfaip6/Dysf/Ptger3/St3gal4/Mpp1/Ptn	27
GO:0070374	positive regulation of ERK1 and ERK2 cascade	BP	0.119	1.47e-06	2.92e-05	4.53	1.99e-05	Angpt1/Dcc/Kdr/Igf1/Ddr2/Adra1a/Npnt/Cd44/Sema7a/Nrp1/Fermt2/Icam1/Tek/Cxcl12/Akap12/Denn2b/Dnajc27/Nox4/Apoe/Havcr2/Ednra/Xcl1/Htr2a/Cavin3/Arrb1/Arrb2/Ccn2	27
GO:0045664	regulation of neuron differentiation	BP	0.116	1.52e-06	3e-05	4.52	2.04e-05	Sfrp2/Fez1/Nlgn1/Rgs6/Ednrb/Dab1/Lrrk2/Mef2c/Id4/Cxcl12/Gdf11/Gprc5b/Gli3/Gdf7/Eif2ak4/Zeb1/Trpc6/Tgif2/Mmd/Hoxd3/Heyl/Zc4h2/Tcf4/Nin/Bin1/Ptger3/Bend6/Cav1	28
GO:0060993	kidney morphogenesis	BP	0.165	1.54e-06	3.03e-05	4.52	2.06e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Lrrk2/Gli3/Tcf21/Tshz3/Agtr1a/Ptch1/Osr1/Dchs1/Fat4	17
GO:0050982	detection of mechanical stimulus	BP	0.21	1.63e-06	3.19e-05	4.5	2.17e-05	Col11a1/Igf1/Scn1a/Grin2b/Serpine2/Cxcl12/Kit/Htr2a/Pkd1/Fyn/Pkd2/Pkdrej/Piezo2	13
GO:0090257	regulation of muscle system process	BP	0.113	1.66e-06	3.24e-05	4.49	2.21e-05	Cacna1c/Ryr1/Igf1/Adra1a/Npnt/Abat/Nos3/Slc8a1/Mef2c/Stc1/Ank2/Slc8a3/Calca/Gucy1a1/Kit/Kcnma1/Myl3/Cmya5/Bin1/Selenon/Pde5a/Cacna1h/Ptger3/Calcrl/Ccn2/Pi16/Atp2b4/Atp1a2/Cav1	29
GO:0032231	regulation of actin filament bundle assembly	BP	0.157	1.7e-06	3.29e-05	4.48	2.24e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Ppm1e/Arhgap28/Dlc1/Ccn2	18
GO:0032102	negative regulation of response to external stimulus	BP	0.0968	1.7e-06	3.29e-05	4.48	2.24e-05	Hgf/Acod1/Sema5a/Mdk/Pla2g10/Cd109/Igf1/Sema5b/Tfpi/Abat/Aph1b/Phldb2/Cd44/Sema7a/Nrp1/Ets1/Foxf1/Serpine2/Fndc4/Cdh5/Prdm1/Nlgn3/Apoe/Havcr2/Cd200/Igf2/Sema3g/Pros1/Rtn4rl1/Tnfaip6/Mapkbp1/Arrb2/Neo1/Ptger3/Calcrl/Xylt1/Sema6a/Cd96/Nr1h3	39
GO:0055123	digestive system development	BP	0.144	1.79e-06	3.46e-05	4.46	2.35e-05	Stra6/Ihh/Sfrp2/Igf1/Clmp/Pkdcc/Tbx2/Ednrb/Foxf1/Gli3/Tcf21/Prdm1/Kit/Cdkn1c/Igf2/Pcsk5/Dchs1/Fat4/Dact1/Stx2	20
GO:0006937	regulation of muscle contraction	BP	0.134	1.85e-06	3.56e-05	4.45	2.42e-05	Cacna1c/Ryr1/Adra1a/Npnt/Abat/Slc8a1/Stc1/Ank2/Slc8a3/Calca/Gucy1a1/Kit/Kcnma1/Myl3/Bin1/Pde5a/Cacna1h/Ptger3/Calcrl/Ccn2/Atp1a2/Cav1	22
GO:0006486	protein glycosylation	BP	0.126	1.92e-06	3.64e-05	4.44	2.48e-05	St6gal2/St8sia2/St8sia4/Gxylt2/Tet1/Uggt2/Tmtc1/B3galnt1/Fut10/Galnt16/St6galnac4/St3gal2/Eogt/Ggta1/St8sia6/Galntl6/Poglut2/Aqp11/Mgat3/B3gnt5/St6galnac6/St3gal4/Large1/Alg14	24
GO:0043413	macromolecule glycosylation	BP	0.126	1.92e-06	3.64e-05	4.44	2.48e-05	St6gal2/St8sia2/St8sia4/Gxylt2/Tet1/Uggt2/Tmtc1/B3galnt1/Fut10/Galnt16/St6galnac4/St3gal2/Eogt/Ggta1/St8sia6/Galntl6/Poglut2/Aqp11/Mgat3/B3gnt5/St6galnac6/St3gal4/Large1/Alg14	24
GO:0043524	negative regulation of neuron apoptotic process	BP	0.126	1.92e-06	3.64e-05	4.44	2.48e-05	Ptprz1/Angpt1/Mdk/Kdr/Agap2/Nrp1/Tert/Bok/Mef2c/Pcdhgc3/Coro1a/Il27ra/Grik2/Apoe/Ndnf/Arrb1/Hipk2/Nfatc4/Arrb2/Fyn/Bhlhb9/Syngap1/Nes/Cacna1a	24
GO:0043534	blood vessel endothelial cell migration	BP	0.155	1.93e-06	3.65e-05	4.44	2.48e-05	Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Mef2c/Prkd1/Vash1/Cdh5/Jcad/Sh3bp1/Vegfc/Apoe/Igf2/Hdac9/Atp2b4/Akt3	18
GO:0072078	nephron tubule morphogenesis	BP	0.181	1.94e-06	3.66e-05	4.44	2.49e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gli3/Tcf21/Agtr1a/Ptch1/Osr1/Dchs1/Fat4	15
GO:0003206	cardiac chamber morphogenesis	BP	0.138	1.95e-06	3.67e-05	4.43	2.5e-05	Col11a1/Sfrp2/Wnt11/Nog/Tbx2/Nos3/Nrp1/Foxf1/Mef2c/Tek/Adamts1/Lrp2/Cpe/Ccm2l/Aplnr/Tbx3/Heyl/Ednra/Myl3/Heg1/Fzd2	21
GO:0072132	mesenchyme morphogenesis	BP	0.222	2.13e-06	3.99e-05	4.4	2.71e-05	Lef1/Wnt11/Nog/Tbx2/Nos3/Foxf1/Aplnr/Tbx3/Heyl/Snai1/Osr1/Dchs1	12
GO:0010749	regulation of nitric oxide mediated signal transduction	BP	0.545	2.22e-06	4.13e-05	4.38	2.81e-05	Spink1/Cbs/Gucy1a2/Gucy1a1/Pde5a/Atp2b4	6
GO:0014832	urinary bladder smooth muscle contraction	BP	0.545	2.22e-06	4.13e-05	4.38	2.81e-05	Cacna1c/P2rx2/Kcnma1/Htr2a/Ptger3/Atp2b4	6
GO:0051495	positive regulation of cytoskeleton organization	BP	0.122	2.26e-06	4.16e-05	4.38	2.83e-05	Sema5a/Wnt11/Evl/Ccdc88a/Nrp1/Fermt2/Wasf3/Pfn2/Icam1/Tek/Abi2/Ppm1f/Limch1/Nox4/Arhgef15/Ppm1e/Scin/Nckap1l/Slain1/Nin/Bin1/Ccn2/Cdc42ep5/Nes/Cav1	25
GO:0120032	regulation of plasma membrane bounded cell projection assembly	BP	0.122	2.26e-06	4.16e-05	4.38	2.83e-05	Gap43/Evl/Nlgn1/Ccdc88a/Nrp1/Adamts16/Abi3/Pfn2/Icam1/Podxl/Abi2/Kit/Rp1/Kctd17/Eps8l1/Daam2/Crocc/Ttbk2/Dzip1/Palm/Dync2li1/Dpysl3/Cdc42ep5/Cep97/Cav1	25
GO:0030048	actin filament-based movement	BP	0.147	2.26e-06	4.16e-05	4.38	2.83e-05	Sgcd/Cacna1c/Kcnd3/Evl/Scn4b/Scn1a/Cacna2d1/Myo5a/Stc1/Ank2/Limch1/Bin1/Epdr1/Myo1f/Cacna1h/Ptger3/Wipf1/Atp1a2/Cav1	19
GO:0060675	ureteric bud morphogenesis	BP	0.189	2.41e-06	4.42e-05	4.35	3e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gli3/Tcf21/Agtr1a/Ptch1/Dchs1/Fat4	14
GO:0017157	regulation of exocytosis	BP	0.113	2.46e-06	4.51e-05	4.35	3.07e-05	Nlgn1/Syt13/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Foxf1/Myo5a/Pfn2/Mical1/Ppfia2/Htr1b/Cadps/Syt7/Htr2a/Nckap1l/Ncs1/Cd84/Cacna1h/Septin4/Fgr/Rab27a/Nrn1/Slc4a8/Cacna1a/Cacnb4	28
GO:0010563	negative regulation of phosphorus metabolic process	BP	0.0919	2.62e-06	4.75e-05	4.32	3.23e-05	Hgf/Sfrp2/Angpt1/Cd109/Spink1/Nog/Igf1/Ddr2/Ptpro/Slc8a1/Lrrk2/Mical1/Mapk8ip1/Slc8a3/Pkia/Thy1/Plpp3/Ppm1f/Ppp1r16b/Cdkn1c/Prr5l/Apoe/Enpp1/Ppef2/Rasip1/Emilin1/Pecam1/Ppm1e/Bdkrb2/Nckap1l/Pkib/Cmya5/Lpcat1/Arrb1/Heg1/Rassf2/Arrb2/Ppp1r26/Lats2/Smpd1/Cav1/Pid1	42
GO:0045936	negative regulation of phosphate metabolic process	BP	0.0919	2.62e-06	4.75e-05	4.32	3.23e-05	Hgf/Sfrp2/Angpt1/Cd109/Spink1/Nog/Igf1/Ddr2/Ptpro/Slc8a1/Lrrk2/Mical1/Mapk8ip1/Slc8a3/Pkia/Thy1/Plpp3/Ppm1f/Ppp1r16b/Cdkn1c/Prr5l/Apoe/Enpp1/Ppef2/Rasip1/Emilin1/Pecam1/Ppm1e/Bdkrb2/Nckap1l/Pkib/Cmya5/Lpcat1/Arrb1/Heg1/Rassf2/Arrb2/Ppp1r26/Lats2/Smpd1/Cav1/Pid1	42
GO:0072088	nephron epithelium morphogenesis	BP	0.176	2.65e-06	4.8e-05	4.32	3.26e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gli3/Tcf21/Agtr1a/Ptch1/Osr1/Dchs1/Fat4	15
GO:0070509	calcium ion import	BP	0.167	2.72e-06	4.91e-05	4.31	3.34e-05	Cacna1c/Spink1/Slc8a1/Slc24a4/Stc1/Cxcl12/Cacna1e/Slc8a3/Nalf1/Agtr1a/Dysf/Cacna1h/Fyn/Pkd2/Slc25a23/Cacna1a	16
GO:0070977	bone maturation	BP	0.3	2.77e-06	4.98e-05	4.3	3.39e-05	Ryr1/Plxnb1/Igf1/Thbs3/Enpp1/Adamts7/Dchs1/Xylt1/Fat4	9
GO:2001257	regulation of cation channel activity	BP	0.127	2.81e-06	5.01e-05	4.3	3.41e-05	Nlgn1/Drd4/Cacna2d1/Mef2c/Myo5a/Ank2/Nlgn3/Cracr2a/Prrt1/Ednra/Stac2/Cacng7/Dysf/Asph/Selenon/Rrad/Pkd2/Dlg4/Gstm7/Gnb5/Cav1/Cacna1a/Cacnb4	23
GO:0051209	release of sequestered calcium ion into cytosol	BP	0.151	2.81e-06	5.01e-05	4.3	3.41e-05	Ryr1/Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Xcl1/Htr2a/Asph/Ryr3/Selenon/Xcr1/Pkd2/Gstm7	18
GO:0048588	developmental cell growth	BP	0.108	2.81e-06	5.01e-05	4.3	3.41e-05	Map2/Sema5a/Itga4/Col14a1/Igf1/St8sia2/Sema5b/Zeb2/Adra1a/Cpne5/Sema7a/Nrp1/Fn1/Cxcl12/Edn3/Eif2ak4/Postn/Ndn/Nlgn3/Apoe/Ednra/Sema3g/Slc23a2/Nin/Epha7/Cacng7/Pi16/Sema6a/Nrn1/Cyfip2	30
GO:0060828	regulation of canonical Wnt signaling pathway	BP	0.112	2.89e-06	5.13e-05	4.29	3.49e-05	Gli1/Sfrp2/Sema5a/Mdk/Wnt11/Nog/Zeb2/Ptpro/Nkd1/Cdh2/Gpc3/Lrrk2/Rbms3/Gprc5b/Gli3/Peg12/Dkk3/Znrf3/Apoe/Caprin2/Daam2/Prickle1/Tle1/Lats2/Adgra2/Cav1/Dact1/Nkd2	28
GO:0060491	regulation of cell projection assembly	BP	0.12	2.94e-06	5.21e-05	4.28	3.54e-05	Gap43/Evl/Nlgn1/Ccdc88a/Nrp1/Adamts16/Abi3/Pfn2/Icam1/Podxl/Abi2/Kit/Rp1/Kctd17/Eps8l1/Daam2/Crocc/Ttbk2/Dzip1/Palm/Dync2li1/Dpysl3/Cdc42ep5/Cep97/Cav1	25
GO:0051283	negative regulation of sequestering of calcium ion	BP	0.15	3.18e-06	5.6e-05	4.25	3.81e-05	Ryr1/Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Xcl1/Htr2a/Asph/Ryr3/Selenon/Xcr1/Pkd2/Gstm7	18
GO:0043536	positive regulation of blood vessel endothelial cell migration	BP	0.214	3.2e-06	5.63e-05	4.25	3.83e-05	Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Prkd1/Jcad/Vegfc/Igf2/Hdac9/Akt3	12
GO:0060537	muscle tissue development	BP	0.0892	3.28e-06	5.73e-05	4.24	3.9e-05	Gli1/Col11a1/Stra6/Ihh/AW551984/Angpt1/Lef1/Sgcd/Hoxd10/Col14a1/Ryr1/Nog/Igf1/Tbx2/Adra1a/Slc8a1/P2rx2/Hoxd9/Mef2c/Tcf21/Lrp2/Tshz3/Ccm2l/Nox4/Tbx3/Heyl/Gjc1/Ednra/Igf2/Myl3/Hdac9/Heg1/Dysf/Selenon/Osr1/Arrb2/Pi16/Hlf/Efemp2/Sgcb/Cav1/Zfp689/Usp2/Itga8	44
GO:0007628	adult walking behavior	BP	0.234	3.28e-06	5.73e-05	4.24	3.9e-05	Efnb3/Cacna1c/Scn1a/Dab1/Glrb/Enpp1/Kcnma1/Hipk2/Arrb2/Cacna1a/Cacnb4	11
GO:0001764	neuron migration	BP	0.122	3.33e-06	5.79e-05	4.24	3.94e-05	Ptprz1/Mdk/Dcc/Mark1/Nrp1/Dab1/Mef2c/Cxcl12/Tbc1d24/Cep85l/Ndn/Gpr173/Matn2/Ndnf/Lhx6/Lrp12/Nr2f1/Neo1/Fyn/Septin4/Fat3/Sema6a/Ntng1/Bbs1	24
GO:0048015	phosphatidylinositol-mediated signaling	BP	0.129	3.39e-06	5.88e-05	4.23	4e-05	Myo16/Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Car8/Npr3/Hcls1/Fn1/Serpine2/Tek/Plcb1/Ppp1r16b/Prr5l/Htr2a/Prex2/Ncs1/Plcb2/Fyn/Fgr	22
GO:0072028	nephron morphogenesis	BP	0.172	3.58e-06	6.19e-05	4.21	4.21e-05	Wnt6/Hoxd11/Nog/Npnt/Cd44/Hoxa11/Adamts16/Gpc3/Gli3/Tcf21/Agtr1a/Ptch1/Osr1/Dchs1/Fat4	15
GO:0002026	regulation of the force of heart contraction	BP	0.29	3.76e-06	6.46e-05	4.19	4.39e-05	Adra1a/Nos3/Slc8a1/Myl3/Pde5a/Apln/Atp2b4/Atp1a2/Cav1	9
GO:2000352	negative regulation of endothelial cell apoptotic process	BP	0.29	3.76e-06	6.46e-05	4.19	4.39e-05	Sema5a/Angpt1/Kdr/Tert/Icam1/Tek/Cdh5/Ndnf/Angptl4	9
GO:0060349	bone morphogenesis	BP	0.155	3.91e-06	6.69e-05	4.17	4.55e-05	Ihh/Mmp16/Sfrp2/Hoxd11/Thbs3/Cbs/Hoxa11/Mef2c/Osr2/Stc1/Has2/Gli3/Frem1/Col13a1/Enpp1/Ltbp3/Rab23	17
GO:1903706	regulation of hemopoiesis	BP	0.0945	4.01e-06	6.86e-05	4.16	4.66e-05	Ihh/Lef1/Mdk/Cd83/P4htm/Cd44/Hcls1/Ets1/Mef2c/Inpp4b/Pik3r6/Lrrc17/Gli3/Calca/Flt3/Zeb1/Prdm1/Cd1d1/Loxl3/Tnfrsf11b/Gpr171/Sox12/Scin/Zbtb46/Nckap1l/Tal1/Hoxa9/Kitl/Tnfaip6/Twist2/Rassf2/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Ptn/Il2rg	38
GO:0070372	regulation of ERK1 and ERK2 cascade	BP	0.101	4.03e-06	6.86e-05	4.16	4.67e-05	Angpt1/Dcc/Kdr/Igf1/Ddr2/Adra1a/Npnt/Cd44/Sema7a/Nrp1/Fermt2/Fn1/Icam1/Tek/Cxcl12/Akap12/Denn2b/Dnajc27/Nox4/Apoe/Havcr2/Emilin1/Ednra/Spred3/Xcl1/Htr2a/Cavin3/Arrb1/Epha7/Arrb2/Ccn2/Sema6a/Cav1	33
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	BP	0.229	4.1e-06	6.95e-05	4.16	4.73e-05	Wnt11/Lrrc7/Foxf1/Dlg2/Msn/Lin7a/Prickle2/Myo9a/Sh3bp1/Pard3b/Dlg5	11
GO:0042098	T cell proliferation	BP	0.115	4.25e-06	7.16e-05	4.15	4.87e-05	Ihh/Igf1/Cd44/Cxcl12/Mapk8ip1/Dock2/Tnfsf13b/Cd1d1/Msn/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Havcr2/Igf2/Xcl1/Nckap1l/Satb1/Pde5a/Fyn/H2-Aa/Stat5b/Zap70/Dlg5/Il12rb1	26
GO:0071560	cellular response to transforming growth factor beta stimulus	BP	0.115	4.25e-06	7.16e-05	4.15	4.87e-05	Cd109/Zeb2/Npnt/Nos3/Fermt2/Mef2c/Cdh5/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Xcl1/Smad9/Ltbp3/Hipk2/Nrros/Zfyve9/Cldn5/Arrb2/Fyn/Il17rd/Lats2/Cav1/Itga8	26
GO:0007265	Ras protein signal transduction	BP	0.0994	4.3e-06	7.24e-05	4.14	4.92e-05	Igf1/Adra1a/Rasgrp3/Nrp1/Cdh2/Arl6/Rasa3/Lpar4/Prkd1/Arhgef25/Cdh13/Rasgrp2/Dock2/Sh2b2/Syde1/Abi2/Sh3bp1/Apoe/Agtr1a/Rasip1/Eps8l1/Ednra/Pecam1/Arap3/Kitl/Arrb1/Heg1/Dlc1/Net1/Lat/Syngap1/Rab39b/Cdc42ep5/Mapre2	34
GO:0044782	cilium organization	BP	0.0954	4.38e-06	7.33e-05	4.13	4.99e-05	Tub/Ccdc88a/Adamts16/Dzip1l/Arl6/Wdr35/Cibar1/Tmem237/Bbs7/Dnah5/Zfp423/Armc9/Ift57/Ptpdc1/Catip/Rp1/Kctd17/Cplane1/Rilpl1/Dync2h1/Crocc/Arl3/Cfap410/Tmem231/Ttc26/Ttbk2/Dzip1/Cep19/Pkd2/Dnah7b/Iqcb1/Rab23/Dnah1/Dync2li1/Lrrc49/Cep97/Bbs1	37
GO:0046631	alpha-beta T cell activation	BP	0.124	4.48e-06	7.48e-05	4.13	5.09e-05	Ihh/Lef1/Cd83/Wdfy4/Cd44/Itk/Mapk8ip1/Gli3/Dock2/Prdm1/Cd1d1/Loxl3/Btla/H2-Ab1/Cracr2a/Xcl1/Nckap1l/Satb1/Gimap5/Zap70/Gimap3/Il12rb1/Il2rg	23
GO:0048017	inositol lipid-mediated signaling	BP	0.127	4.53e-06	7.52e-05	4.12	5.12e-05	Myo16/Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Car8/Npr3/Hcls1/Fn1/Serpine2/Tek/Plcb1/Ppp1r16b/Prr5l/Htr2a/Prex2/Ncs1/Plcb2/Fyn/Fgr	22
GO:0051017	actin filament bundle assembly	BP	0.127	4.53e-06	7.52e-05	4.12	5.12e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Aif1l/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Ppm1e/Arrb1/Arhgap28/Dlc1/Ccn2/Dpysl3/Shroom1	22
GO:0006790	sulfur compound metabolic process	BP	0.101	4.59e-06	7.6e-05	4.12	5.17e-05	Acsl6/Angpt1/Hmgcs2/Chst2/Cbs/Acacb/Spock2/Ednrb/Mical1/Tpst1/Egflam/Gamt/Gstm6/Them5/Mamdc2/Chst1/Cth/Phgdh/Nox4/Enpp1/Ednra/Ndnf/Acot7/Bgn/Gstm7/Gstm1/Stat5b/Xylt1/Dse/Ggt7/Acsl1/Cacna1a/Sult1a1	33
GO:0051496	positive regulation of stress fiber assembly	BP	0.207	4.73e-06	7.81e-05	4.11	5.31e-05	Wnt11/Evl/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Ppm1e/Ccn2	12
GO:0048265	response to pain	BP	0.25	4.84e-06	7.96e-05	4.1	5.42e-05	Grik1/Slc6a2/P2rx2/Ednrb/Grin2b/Cacna1e/Calca/Kcnip3/Vwa1/Cacna1a	10
GO:0071772	response to BMP	BP	0.123	4.9e-06	8.02e-05	4.1	5.45e-05	Sfrp2/Lef1/Kdr/Nog/Kcnd3/Rnf165/Fst/Gpc3/Vstm2a/Zfp423/Lrp2/Gdf7/Cdh5/Heyl/Adamts7/Kcp/Smad9/Tnfaip6/Hipk2/Neo1/Fstl1/Cav1/Tmprss6	23
GO:0071773	cellular response to BMP stimulus	BP	0.123	4.9e-06	8.02e-05	4.1	5.45e-05	Sfrp2/Lef1/Kdr/Nog/Kcnd3/Rnf165/Fst/Gpc3/Vstm2a/Zfp423/Lrp2/Gdf7/Cdh5/Heyl/Adamts7/Kcp/Smad9/Tnfaip6/Hipk2/Neo1/Fstl1/Cav1/Tmprss6	23
GO:0098703	calcium ion import across plasma membrane	BP	0.281	5.03e-06	8.2e-05	4.09	5.58e-05	Cacna1c/Slc8a1/Slc24a4/Cacna1e/Slc8a3/Nalf1/Agtr1a/Fyn/Cacna1a	9
GO:0045761	regulation of adenylate cyclase activity	BP	0.224	5.08e-06	8.23e-05	4.08	5.6e-05	Cacna1c/Vipr2/Npr3/Adcy3/Calca/Adcy4/Adcy7/Cap2/Gng7/Palm/Gabbr1	11
GO:0071526	semaphorin-plexin signaling pathway	BP	0.224	5.08e-06	8.23e-05	4.08	5.6e-05	Sema5a/Plxnb1/Sema5b/Sema7a/Nrp1/Mef2c/Plxnd1/Sh3bp1/Ednra/Sema3g/Sema6a	11
GO:0019233	sensory perception of pain	BP	0.134	5.32e-06	8.59e-05	4.07	5.85e-05	Kcnd2/Scn1a/Ednrb/Ano1/Grin2b/Cxcl12/Cacna1e/Calca/Mme/Dlg2/Ndn/Kcnc4/Ednra/Htr2a/Kcnip3/Cacna1h/Arrb2/Fyn/Scn3a/Cacna1a	20
GO:0031279	regulation of cyclase activity	BP	0.203	5.71e-06	9.17e-05	4.04	6.24e-05	Cacna1c/Vipr2/Nos3/Npr3/Adcy3/Calca/Adcy4/Adcy7/Cap2/Gng7/Palm/Gabbr1	12
GO:0150116	regulation of cell-substrate junction organization	BP	0.188	5.75e-06	9.21e-05	4.04	6.26e-05	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Thy1/Epha3/Ppm1f/Limch1/Arhgap6/Dlc1/Mapre2	13
GO:0071559	response to transforming growth factor beta	BP	0.113	5.86e-06	9.35e-05	4.03	6.36e-05	Cd109/Zeb2/Npnt/Nos3/Fermt2/Mef2c/Cdh5/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Xcl1/Smad9/Ltbp3/Hipk2/Nrros/Zfyve9/Cldn5/Arrb2/Fyn/Il17rd/Lats2/Cav1/Itga8	26
GO:0061572	actin filament bundle organization	BP	0.125	6.01e-06	9.56e-05	4.02	6.5e-05	Kank4/Wnt11/Evl/Phldb2/Ccdc88a/Nrp1/Fermt2/Aif1l/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Arhgap6/Tmeff2/Ppm1e/Arrb1/Arhgap28/Dlc1/Ccn2/Dpysl3/Shroom1	22
GO:0048167	regulation of synaptic plasticity	BP	0.0952	6.04e-06	9.58e-05	4.02	6.52e-05	Grik1/Kdr/Nog/Jph4/Grid2ip/Nlgn1/Rims3/Mef2c/Grin2b/Serpine2/Shank2/Slc8a3/Eif2ak4/Tshz3/Mme/Kit/Nlgn3/Nrgn/Sorcs2/Grik2/Apoe/Prrt1/Cd38/Enpp1/Syt7/Prrt2/Nsg1/Cyp46a1/Erc2/Mpp2/Nfatc4/Dlg4/Brsk1/Syngap1/Ptn/Cpeb1	36
GO:0150115	cell-substrate junction organization	BP	0.157	6.13e-06	9.7e-05	4.01	6.6e-05	Kdr/Phldb2/Nrp1/Fermt2/Fn1/Col16a1/Tek/Thsd1/Thy1/Epha3/Ppm1f/Limch1/Arhgap6/Dlc1/Mapre2/Itgb4	16
GO:0003197	endocardial cushion development	BP	0.22	6.26e-06	9.85e-05	4.01	6.7e-05	Nog/Tbx2/Nos3/Foxf1/Erg/Epha3/Aplnr/Tbx3/Heyl/Snai1/Dchs1	11
GO:0090659	walking behavior	BP	0.22	6.26e-06	9.85e-05	4.01	6.7e-05	Efnb3/Cacna1c/Scn1a/Dab1/Glrb/Enpp1/Kcnma1/Hipk2/Arrb2/Cacna1a/Cacnb4	11
GO:0003231	cardiac ventricle development	BP	0.132	6.53e-06	0.000102	3.99	6.97e-05	Col11a1/Stra6/Sfrp2/Wnt11/Nog/Nos3/Foxf1/Mef2c/Lrp2/Cpe/Prdm1/Ccm2l/Aplnr/Cplane1/Tbx3/Heyl/Ednra/Myl3/Heg1/Fzd2	20
GO:1902656	calcium ion import into cytosol	BP	0.273	6.65e-06	0.000104	3.98	7.08e-05	Cacna1c/Slc8a1/Slc24a4/Cacna1e/Slc8a3/Nalf1/Agtr1a/Fyn/Cacna1a	9
GO:0031503	protein-containing complex localization	BP	0.118	6.68e-06	0.000104	3.98	7.09e-05	Gpc6/Sgcd/Tub/Nlgn1/Lrrc7/Cep112/Drd4/Stx1b/Nptx1/Wdr35/Exoc3l/Ift57/Dlg2/Nptxr/Magi2/Dync2h1/Nsg1/Arl3/Cacng7/Ttc26/Dzip1/Dlg4/Dync2li1/Bbs1	24
GO:0043393	regulation of protein binding	BP	0.115	6.82e-06	0.000106	3.97	7.22e-05	Map2/Angpt1/Itga4/Nog/Tert/Lrrk2/Hopx/Plxnd1/Lfng/Ccm2l/Apoe/Caprin2/Arrb1/Hipk2/Pkd1/Dysf/Ttbk2/Nfatc4/Cldn5/Arrb2/Dzip1/Mfng/Nes/Cav1/Dact1	25
GO:0051588	regulation of neurotransmitter transport	BP	0.137	6.94e-06	0.000108	3.97	7.32e-05	Nlgn1/Adra1a/Rims3/Drd4/Stx1b/P2rx2/Lrrk2/Mef2c/Pfn2/Edn3/Ppfia2/Htr1b/Kcnc4/Htr2a/Ncs1/Nrn1/Slc4a8/Cacna1a/Cacnb4	19
GO:0042063	gliogenesis	BP	0.0971	7.1e-06	0.00011	3.96	7.47e-05	Gap43/Ptprz1/Lef1/Mdk/Apcdd1/Nog/Igf1/Lamc3/Cspg4/Tert/Cdh2/Wasf3/Areg/Fn1/Dab1/Id4/Serpine2/Gli3/Slc8a3/Lrp2/Plpp3/Ndn/Nlgn3/Matn2/Phgdh/Enpp1/Daam2/Tal1/Bin1/Zcchc24/Nrros/Ptn/Tppp/Itgb4	34
GO:0050806	positive regulation of synaptic transmission	BP	0.0985	7.19e-06	0.000111	3.96	7.54e-05	Slc1a3/Gria4/Grik1/Nog/Nlgn1/Adra1a/Rims3/Stx1b/Grin2b/Serpine2/Shank2/Slc8a3/Eif2ak4/Tshz3/Syde1/Mme/Lama2/Nlgn3/Nrgn/Grik2/Apoe/Prrt1/Enpp1/Nsg1/Cacng7/Cyp46a1/Ncs1/Mpp2/Nfatc4/Arrb2/Dlg4/Ptn/Slc4a8	33
GO:0046634	regulation of alpha-beta T cell activation	BP	0.148	7.23e-06	0.000111	3.95	7.56e-05	Ihh/Cd83/Cd44/Mapk8ip1/Gli3/Prdm1/Cd1d1/Loxl3/Btla/H2-Ab1/Xcl1/Nckap1l/Gimap5/Zap70/Gimap3/Il12rb1/Il2rg	17
GO:0051056	regulation of small GTPase mediated signal transduction	BP	0.112	7.41e-06	0.000114	3.94	7.72e-05	Igf1/Adra1a/Nrp1/Cdh2/Garnl3/Rasa3/Lpar4/Arhgef25/Arhgap25/Dock2/Sh2b2/Syde1/Sh3bp1/Apoe/Rasip1/Eps8l1/Adcyap1r1/Arap3/Kitl/Arrb1/Heg1/Arhgap28/Dlc1/Net1/Syngap1/Mapre2	26
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	BP	0.12	7.64e-06	0.000117	3.93	7.94e-05	Ptprz1/Hgf/Angpt1/Igf1/Adra1a/Cd44/Hcls1/Nrp1/Cspg4/Areg/Icam1/Gprc5b/Plpp3/Kit/Vegfc/Nox4/Igf2/Pecam1/Htr2a/Kitl/Arrb2/Fyn/Dlg4	23
GO:0030900	forebrain development	BP	0.093	7.81e-06	0.000119	3.92	8.1e-05	Gli1/Sema5a/Lef1/Mdk/Nog/Zeb2/Sema7a/Nrp1/Cdh2/Dab1/Lrrk2/Id4/Fut10/Cxcl12/Dnah5/Gli3/Plcb1/Lrp2/Gdf7/D16Ertd472e/Kif1a/Tsku/Tbx3/Dync2h1/Ndnf/Dclk2/Lhx6/Rtn4rl1/Nin/Nr2f1/Ttbk2/Dlc1/Ptger3/Fyn/Atp1a2/Fat4/Bbs1	37
GO:0030510	regulation of BMP signaling pathway	BP	0.154	7.92e-06	0.00012	3.92	8.19e-05	Sfrp2/Kdr/Nog/Rnf165/Fst/Gpc3/Zfp423/Lrp2/Cdh5/Kcp/Tnfaip6/Hipk2/Neo1/Fstl1/Cav1/Tmprss6	16
GO:0030282	bone mineralization	BP	0.141	8.05e-06	0.000122	3.91	8.3e-05	Wnt11/Igf1/Pkdcc/Ddr2/Slc8a1/Gpc3/Mef2c/Osr2/Slc24a3/Nell1/Pth1r/Mgp/Enpp1/Ltbp3/Osr1/Fgr/Ptn/Dnm3os	18
GO:0070661	leukocyte proliferation	BP	0.0951	8.33e-06	0.000126	3.9	8.56e-05	Ihh/Lef1/Igf1/Cd44/Npr3/Mef2c/Cxcl12/Mapk8ip1/Dock2/Flt3/Tnfsf13b/Prdm1/Cd1d1/Msn/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Satb1/Kitl/Csf2rb/Pde5a/Fyn/H2-Aa/Stat5b/Zap70/Impdh1/Dlg5/Il12rb1	35
GO:0048799	animal organ maturation	BP	0.265	8.71e-06	0.000131	3.88	8.93e-05	Ryr1/Plxnb1/Igf1/Thbs3/Enpp1/Adamts7/Dchs1/Xylt1/Fat4	9
GO:0042326	negative regulation of phosphorylation	BP	0.0925	8.75e-06	0.000131	3.88	8.94e-05	Hgf/Sfrp2/Angpt1/Cd109/Spink1/Nog/Igf1/Ddr2/Ptpro/Slc8a1/Lrrk2/Mical1/Mapk8ip1/Slc8a3/Pkia/Thy1/Plpp3/Ppm1f/Cdkn1c/Prr5l/Apoe/Enpp1/Ppef2/Rasip1/Emilin1/Pecam1/Ppm1e/Bdkrb2/Pkib/Arrb1/Heg1/Rassf2/Arrb2/Lats2/Smpd1/Cav1/Pid1	37
GO:0031644	regulation of nervous system process	BP	0.119	9.08e-06	0.000136	3.87	9.25e-05	Hgf/Begain/Igf1/Nlgn1/Abat/Celf4/Nos3/Drd4/Stx1b/Ednrb/Wasf3/Lrrk2/Nptx1/Grin2b/Tbc1d24/Slc8a3/Calca/Nlgn3/Nptxr/Kcnc4/Dlg4/Cux2/Tppp	23
GO:0061028	establishment of endothelial barrier	BP	0.212	9.37e-06	0.00014	3.85	9.53e-05	Ednrb/Icam1/Plcb1/Cdh5/Msn/Ppp1r16b/Robo4/Ednra/Pecam1/Cldn5/Cldn1	11
GO:0030203	glycosaminoglycan metabolic process	BP	0.16	9.58e-06	0.000143	3.85	9.71e-05	Angpt1/Cd44/Spock2/Ednrb/Has2/Egflam/Mamdc2/Chst1/Ednra/Ndnf/Tnfaip6/Bgn/Xylt1/Dse/Habp4	15
GO:0060271	cilium assembly	BP	0.0958	9.61e-06	0.000143	3.85	9.72e-05	Ccdc88a/Adamts16/Dzip1l/Arl6/Wdr35/Cibar1/Tmem237/Bbs7/Dnah5/Zfp423/Armc9/Ift57/Ptpdc1/Rp1/Kctd17/Cplane1/Rilpl1/Dync2h1/Crocc/Arl3/Cfap410/Tmem231/Ttc26/Ttbk2/Dzip1/Cep19/Dnah7b/Iqcb1/Rab23/Dnah1/Dync2li1/Lrrc49/Cep97/Bbs1	34
GO:0048593	camera-type eye morphogenesis	BP	0.129	9.73e-06	0.000144	3.84	9.81e-05	Stra6/Ihh/Sdk2/Kdr/Tbx2/Arl6/Tenm3/Gdf11/Obsl1/Gli3/Thy1/Zeb1/Ptprm/Abi2/Rp1/Tsku/Rorb/Hipk2/Fat3/Ptn	20
GO:0001736	establishment of planar polarity	BP	0.194	9.8e-06	0.000144	3.84	9.83e-05	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Cplane1/Dchs1/Fzd2/Nphp1/Fat4/Brsk1/Dact1	12
GO:0051339	regulation of lyase activity	BP	0.194	9.8e-06	0.000144	3.84	9.83e-05	Cacna1c/Vipr2/Nos3/Npr3/Adcy3/Calca/Adcy4/Adcy7/Cap2/Gng7/Palm/Gabbr1	12
GO:0003279	cardiac septum development	BP	0.138	1e-05	0.000147	3.83	1e-04	Stra6/Wnt11/Nog/Tbx2/Nos3/Nrp1/Kif7/Ank2/Lrp2/Plxnd1/Prdm1/Aplnr/Cplane1/Tbx3/Heyl/Pcsk5/Heg1/Fzd2	18
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	BP	0.105	1.02e-05	0.00015	3.82	0.000102	Ptprz1/Hgf/Sfrp2/Angpt1/Spink1/Igf1/Adra1a/Cd44/Hcls1/Nrp1/Cspg4/Areg/Icam1/Gprc5b/Thy1/Plpp3/Kit/Vegfc/Nox4/Igf2/Pecam1/Htr2a/Kitl/Epha7/Arrb2/Fyn/Dlg4/Cav1	28
GO:0019226	transmission of nerve impulse	BP	0.158	1.09e-05	0.00016	3.8	0.000109	Kcnd2/P2rx2/Scn1a/Jam3/Cacna1e/Scn2a/Nfasc/Grik2/Kcnma1/Kcnc4/Cacng7/Cacna1h/Scn3a/Cacna1a/Cacnb4	15
GO:0061512	protein localization to cilium	BP	0.178	1.1e-05	0.00016	3.8	0.000109	Tub/Ccdc88a/Dzip1l/Arl6/Wdr35/Zfp423/Cplane1/Dync2h1/Crocc/Arl3/Ttc26/Dzip1/Bbs1	13
GO:2000300	regulation of synaptic vesicle exocytosis	BP	0.167	1.13e-05	0.000164	3.79	0.000112	Nlgn1/Adra1a/Rims3/Drd4/P2rx2/Lrrk2/Pfn2/Ppfia2/Htr1b/Htr2a/Ncs1/Nrn1/Slc4a8/Cacnb4	14
GO:1904036	negative regulation of epithelial cell apoptotic process	BP	0.208	1.14e-05	0.000165	3.78	0.000112	Sema5a/Angpt1/Mdk/Kdr/Igf1/Tert/Icam1/Tek/Cdh5/Ndnf/Angptl4	11
GO:0034764	positive regulation of transmembrane transport	BP	0.107	1.14e-05	0.000165	3.78	0.000112	Acsl6/Cacna1c/Igf1/Tcaf1/Drd4/Tert/Gpc3/Cacna2d1/Myo5a/Cxcr3/Edn3/Ank2/Plcb1/Thy1/Trpc6/Nlgn3/Aplnr/Cracr2a/Agtr1a/Ednra/Stac2/Asph/Pkd2/Gstm7/Abcb1a/Acsl1/Cacnb4	27
GO:0045860	positive regulation of protein kinase activity	BP	0.095	1.15e-05	0.000166	3.78	0.000113	Angpt1/Agap2/Igf1/Ddr2/Zeb2/Adra1a/Ccdc88a/Drd4/Fermt2/Areg/Ccnd2/Dab1/Lrrk2/Edn3/Gprc5b/Pik3r6/Calca/Kit/Mmd/Vegfc/Nox4/Agtr1a/Htr2a/Kitl/Pkd1/Rassf2/Pde5a/Arrb2/Pkd2/Dlg4/Atp2b4/Lat/Acsl1/C1qtnf9	34
GO:0045666	positive regulation of neuron differentiation	BP	0.143	1.15e-05	0.000166	3.78	0.000113	Fez1/Rgs6/Dab1/Mef2c/Cxcl12/Gprc5b/Gdf7/Zeb1/Trpc6/Tgif2/Mmd/Hoxd3/Heyl/Zc4h2/Tcf4/Nin/Bend6	17
GO:0001755	neural crest cell migration	BP	0.19	1.16e-05	0.000167	3.78	0.000113	Sema5a/Sema5b/Zeb2/Sema7a/Nrp1/Ednrb/Fn1/Edn3/Ednra/Sema3g/Kitl/Sema6a	12
GO:0007164	establishment of tissue polarity	BP	0.19	1.16e-05	0.000167	3.78	0.000113	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Cplane1/Dchs1/Fzd2/Nphp1/Fat4/Brsk1/Dact1	12
GO:0050769	positive regulation of neurogenesis	BP	0.101	1.21e-05	0.000173	3.76	0.000117	Ptprz1/Sema5a/Mdk/Kdr/Nog/Plxnb1/Ptprd/Igf1/Zeb2/Sema7a/Nrp1/Fn1/Serpine2/Cxcl12/Tbc1d24/Obsl1/Gli3/Lrp2/Plxnd1/Mme/Kit/Vegfc/Apoe/Caprin2/Nin/Bin1/Chodl/Bhlhb9/Cux2/Ptn	30
GO:0007044	cell-substrate junction assembly	BP	0.156	1.25e-05	0.000177	3.75	0.000121	Kdr/Phldb2/Nrp1/Fermt2/Fn1/Col16a1/Tek/Thsd1/Thy1/Epha3/Ppm1f/Limch1/Arhgap6/Dlc1/Itgb4	15
GO:0008154	actin polymerization or depolymerization	BP	0.116	1.27e-05	0.00018	3.74	0.000123	Kank4/Sema5a/Evl/Hcls1/Tmod2/Pfn2/Icam1/Mical1/Catip/Coro1a/Abi2/Esam/Sh3bp1/Daam2/Pecam1/Scin/Nckap1l/Bin1/Arhgap28/Wipf1/Cdc42ep5/Cyfip2/Plekhh2	23
GO:0035088	establishment or maintenance of apical/basal cell polarity	BP	0.204	1.37e-05	0.000193	3.71	0.000131	Wnt11/Lrrc7/Foxf1/Dlg2/Msn/Lin7a/Prickle2/Myo9a/Sh3bp1/Pard3b/Dlg5	11
GO:0061245	establishment or maintenance of bipolar cell polarity	BP	0.204	1.37e-05	0.000193	3.71	0.000131	Wnt11/Lrrc7/Foxf1/Dlg2/Msn/Lin7a/Prickle2/Myo9a/Sh3bp1/Pard3b/Dlg5	11
GO:0033344	cholesterol efflux	BP	0.188	1.38e-05	0.000193	3.71	0.000131	Apob/Pla2g10/Soat1/Pltp/Tsku/Apoe/Abca5/Ptch1/Abcg1/Abca8b/Cav1/Nr1h3	12
GO:0051893	regulation of focal adhesion assembly	BP	0.188	1.38e-05	0.000193	3.71	0.000131	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Thy1/Epha3/Ppm1f/Limch1/Arhgap6/Dlc1	12
GO:0090109	regulation of cell-substrate junction assembly	BP	0.188	1.38e-05	0.000193	3.71	0.000131	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Thy1/Epha3/Ppm1f/Limch1/Arhgap6/Dlc1	12
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	BP	0.11	1.38e-05	0.000193	3.71	0.000131	Vipr2/Adra1a/Adgrl4/Drd4/Npr3/Gnai1/Cxcr3/Adcy3/Akap12/Ptgfr/Adgrl1/Calca/Htr1b/Pth1r/Adcy4/Gpr161/Adcy7/Ednra/Adcyap1r1/Gnaz/Ptger3/Calcrl/Atp2b4/Palm/Gabbr1	25
GO:0035115	embryonic forelimb morphogenesis	BP	0.25	1.45e-05	0.000202	3.7	0.000137	Cacna1c/Hoxd11/Hoxa11/Hoxd9/Osr2/Wnt9a/Tbx3/Hoxa9/Osr1	9
GO:0010595	positive regulation of endothelial cell migration	BP	0.147	1.46e-05	0.000202	3.7	0.000137	Sema5a/Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Prkd1/Tek/Plpp3/Jcad/Vegfc/Igf2/Hdac9/Akt3/Adgra2	16
GO:0106027	neuron projection organization	BP	0.147	1.46e-05	0.000202	3.7	0.000137	Nlgn1/Lrrk2/Grin2b/Ppfia2/Dock10/Kif1a/Abi2/Nlgn3/Apoe/Caprin2/Fyn/Bhlhb9/Dlg4/Cux2/Abcd2/Ngef	16
GO:0007179	transforming growth factor beta receptor signaling pathway	BP	0.118	1.46e-05	0.000202	3.7	0.000137	Cd109/Zeb2/Npnt/Fermt2/Cdh5/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Smad9/Ltbp3/Hipk2/Nrros/Zfyve9/Cldn5/Arrb2/Il17rd/Lats2/Cav1/Itga8	22
GO:0048592	eye morphogenesis	BP	0.118	1.46e-05	0.000202	3.7	0.000137	Stra6/Ihh/Sdk2/Kdr/Tbx2/Arl6/Tenm3/Gdf11/Obsl1/Gli3/Thy1/Zeb1/Prdm1/Ptprm/Abi2/Rp1/Tsku/Rorb/Col5a2/Hipk2/Fat3/Ptn	22
GO:0001894	tissue homeostasis	BP	0.101	1.47e-05	0.000202	3.7	0.000137	Tex15/Ihh/Angpt1/Col14a1/Kdr/Tub/Nos3/Calca/Flt3/Pth1r/Pbld2/Coro1a/Ldb2/Rp1/Tnfrsf11b/Nox4/Cd38/Enpp1/Bdkrb2/Crocc/Lpcat1/Ltbp3/Rcn3/Cldn5/Ccn2/Iqcb1/Akt3/Abcb1a/Bbs1	29
GO:0019229	regulation of vasoconstriction	BP	0.163	1.49e-05	0.000205	3.69	0.000139	Cacna1c/Adra1a/Mmp2/Icam1/Wdr35/Edn3/Cd38/Agtr1a/Htr2a/Pde5a/Ptger3/Apln/Atp1a2/Cav1	14
GO:0061484	hematopoietic stem cell homeostasis	BP	0.286	1.5e-05	0.000205	3.69	0.000139	Gprasp2/Emcn/Crispld1/Myct1/Armcx1/Zfp251/Septin4/Fstl1	8
GO:0097178	ruffle assembly	BP	0.222	1.5e-05	0.000205	3.69	0.00014	Evl/Nlgn1/Cspg4/Aif1l/Pfn2/Icam1/Sh3bp1/Eps8l1/Arhgef26/Cav1	10
GO:0045165	cell fate commitment	BP	0.101	1.57e-05	0.000213	3.67	0.000145	Gap43/Ihh/Sfrp2/Wnt6/AW551984/Ar/Wnt11/Hoxd10/Kdr/Ptch2/Tbx2/Hoxa11/Mef2c/Gli3/Glis1/Gdf7/Wnt9a/Prdm1/Jag2/Loxl3/Prickle2/Sox12/Tbx3/Ednra/Lhx6/Tal1/Ptch1/Ets2/Lats2	29
GO:0001508	action potential	BP	0.129	1.57e-05	0.000213	3.67	0.000145	Cacna1c/Kcnd2/Kcnd3/Adra1a/Scn4b/P2rx2/Scn1a/Cacna2d1/Grin2b/Ank2/Scn2a/Grik2/Kcnma1/Kcnc4/Bin1/Cacna1h/Scn3a/Cav1/Cacnb4	19
GO:0030148	sphingolipid biosynthetic process	BP	0.153	1.61e-05	0.000217	3.66	0.000148	St8sia2/St8sia4/Elovl4/Agk/Cerkl/Sptlc3/Cers4/St6galnac4/St3gal2/St8sia6/Degs2/Abca8b/B3gnt5/St6galnac6/Smpd1	15
GO:0070252	actin-mediated cell contraction	BP	0.153	1.61e-05	0.000217	3.66	0.000148	Sgcd/Cacna1c/Kcnd3/Scn4b/Scn1a/Cacna2d1/Stc1/Ank2/Limch1/Bin1/Epdr1/Cacna1h/Ptger3/Atp1a2/Cav1	15
GO:0032835	glomerulus development	BP	0.185	1.63e-05	0.000219	3.66	0.000149	Angpt1/Nog/Ptpro/Ednrb/Mef2c/Nid1/Tek/Enpep/Tcf21/Heyl/Ednra/Osr1	12
GO:0018209	peptidyl-serine modification	BP	0.0934	1.63e-05	0.000219	3.66	0.000149	Hgf/Sfrp2/Angpt1/Cd44/Spock2/Hcls1/Lrrk2/Pfn2/Prkd1/Tek/Egflam/Galnt16/Rps6ka2/Mamdc2/Ppm1f/Caprin2/Ndnf/Dclk2/Bdkrb2/Rps6ka5/Bgn/Arrb1/Hipk2/Pkd1/Rassf2/Ttbk2/Poglut2/Arrb2/Atp2b4/Akt3/Brsk1/Naa11/Lats2/Cav1	34
GO:0034446	substrate adhesion-dependent cell spreading	BP	0.145	1.64e-05	0.00022	3.66	0.00015	Mdk/Itga4/Lamc3/Nrp1/Fermt2/Itgb7/Fn1/Tek/Has2/Postn/Tmeff2/Parvg/Parvb/Net1/Ntng1/Itga8	16
GO:0051402	neuron apoptotic process	BP	0.0975	1.65e-05	0.000221	3.66	0.00015	Ptprz1/Angpt1/Mdk/Kdr/Agap2/Nrp1/Tert/Bok/Mef2c/Pcdhgc3/Itga1/Scn2a/Coro1a/Il27ra/Grik2/Apoe/Enpp1/Kcnma1/Ndnf/Arrb1/Hipk2/Epha7/Kcnip3/Nlrp1b/Nfatc4/Arrb2/Fyn/Bhlhb9/Syngap1/Nes/Cacna1a	31
GO:0046629	gamma-delta T cell activation	BP	0.333	1.68e-05	0.000224	3.65	0.000152	Lef1/Itk/Jag2/Nckap1l/Stat5b/Gimap5/Gimap3	7
GO:0070371	ERK1 and ERK2 cascade	BP	0.0946	1.68e-05	0.000224	3.65	0.000152	Angpt1/Dcc/Kdr/Igf1/Ddr2/Adra1a/Npnt/Cd44/Sema7a/Nrp1/Fermt2/Fn1/Icam1/Tek/Cxcl12/Akap12/Denn2b/Dnajc27/Nox4/Apoe/Havcr2/Emilin1/Ednra/Spred3/Xcl1/Htr2a/Cavin3/Arrb1/Epha7/Arrb2/Ccn2/Sema6a/Cav1	33
GO:0048659	smooth muscle cell proliferation	BP	0.117	1.73e-05	0.000229	3.64	0.000156	Vipr2/Igf1/Ddr2/Nos3/Drd4/Npr3/Tert/Mmp2/Mef2c/Cdh13/Adamts1/Htr1b/Rgs5/Apoe/Enpp1/Ednra/Irak4/Calcrl/Apln/Stat5b/Efemp2/Cav1	22
GO:0050920	regulation of chemotaxis	BP	0.109	1.73e-05	0.000229	3.64	0.000156	Sema5a/Mdk/Kdr/Sema5b/Sema7a/Nrp1/Fn1/Prkd1/Cxcr3/Cxcl12/Jam3/Cdh13/Edn3/Ppm1f/Vegfc/Ednra/Sema3g/Xcl1/Nckap1l/Tnfaip6/Dysf/Sema6a/Mpp1/Ptn/Adgra2	25
GO:0097529	myeloid leukocyte migration	BP	0.109	1.73e-05	0.000229	3.64	0.000156	Cxcl15/Mdk/Ptpro/Ednrb/Cxcl12/Jam3/Edn3/Itga1/Calca/Plcb1/Kit/Vegfc/Enpp1/Emilin1/Cd200/Ednra/Pecam1/Xcl1/Nckap1l/Tnfaip6/Dysf/Irak4/Ptger3/Stat5b/Mpp1	25
GO:0033002	muscle cell proliferation	BP	0.104	1.74e-05	0.000229	3.64	0.000156	Gli1/Angpt1/Vipr2/Nog/Igf1/Tbx2/Ddr2/Nos3/Drd4/Npr3/Tert/Mmp2/Mef2c/Cdh13/Adamts1/Htr1b/Rgs5/Apoe/Enpp1/Ednra/Selenon/Irak4/Calcrl/Apln/Stat5b/Efemp2/Cav1	27
GO:0001666	response to hypoxia	BP	0.111	1.76e-05	0.000232	3.64	0.000157	Kcnk3/Kcnd2/Ryr1/Kdr/Ddah1/Abat/Slc8a1/Cbs/P2rx2/Pygm/Tert/Mmp2/Grin2b/Tek/Slc8a3/Scn2a/Vegfc/Cd38/Kcnma1/Ednra/Ndnf/Cav1/Cpeb1/Hif3a	24
GO:0046651	lymphocyte proliferation	BP	0.0955	1.83e-05	0.00024	3.62	0.000163	Ihh/Lef1/Igf1/Cd44/Mef2c/Cxcl12/Mapk8ip1/Dock2/Flt3/Tnfsf13b/Prdm1/Cd1d1/Msn/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Satb1/Pde5a/Fyn/H2-Aa/Stat5b/Zap70/Impdh1/Dlg5/Il12rb1	32
GO:0009954	proximal/distal pattern formation	BP	0.243	1.84e-05	0.000241	3.62	0.000164	Gli1/Hoxd10/Hoxd11/Hoxa11/Hoxd9/Hoxa10/Gli3/Hoxa9/Osr1	9
GO:0010524	positive regulation of calcium ion transport into cytosol	BP	0.182	1.91e-05	0.000249	3.6	0.00017	Cxcr3/Thy1/Aplnr/Agtr1a/Ednra/Adcyap1r1/Asph/Pkd2/Gstm7/Gimap5/Gimap3/Cav1	12
GO:0071900	regulation of protein serine/threonine kinase activity	BP	0.0938	2e-05	0.000261	3.58	0.000177	Sfrp2/Igf1/Zeb2/Slc8a1/Cbs/Drd4/Fermt2/Ccnd2/Lrrk2/Mapk8ip1/Edn3/Pik3r6/Slc8a3/Pkia/Thy1/Kit/Cdkn1c/Nox4/Apoe/Rasip1/Htr2a/Pkib/Kitl/Pkd1/Heg1/Pde5a/Pkd2/Atp2b4/Lats2/Smpd1/Acsl1/Cav1/C1qtnf9	33
GO:0050768	negative regulation of neurogenesis	BP	0.123	2.06e-05	0.000268	3.57	0.000182	Prtg/Efnb3/Map2/Sema5a/Nog/Sema5b/Sema7a/Nrp1/Tert/Dab1/Id4/Thy1/Trpc6/Daam2/Sema3g/Epha7/Nfatc4/Syngap1/Sema6a/Ptn	20
GO:1990138	neuron projection extension	BP	0.113	2.07e-05	0.000268	3.57	0.000182	Map2/Sema5a/Itga4/St8sia2/Sema5b/Cpne5/Sema7a/Nrp1/Fn1/Cxcl12/Edn3/Eif2ak4/Postn/Ndn/Nlgn3/Apoe/Ednra/Sema3g/Slc23a2/Cacng7/Sema6a/Nrn1/Cyfip2	23
GO:1904427	positive regulation of calcium ion transmembrane transport	BP	0.157	2.23e-05	0.000287	3.54	0.000195	Cacna1c/Cacna2d1/Cxcr3/Ank2/Thy1/Aplnr/Cracr2a/Agtr1a/Ednra/Stac2/Asph/Pkd2/Gstm7/Cacnb4	14
GO:1990874	vascular associated smooth muscle cell proliferation	BP	0.179	2.24e-05	0.000288	3.54	0.000196	Igf1/Ddr2/Drd4/Tert/Mmp2/Mef2c/Adamts1/Htr1b/Rgs5/Enpp1/Apln/Efemp2	12
GO:0043616	keratinocyte proliferation	BP	0.213	2.26e-05	0.000289	3.54	0.000197	Mdk/Cd109/Fst/Prkd1/Has2/Cdh13/Stxbp4/Klf9/Twist2/Ptch1	10
GO:0050974	detection of mechanical stimulus involved in sensory perception	BP	0.213	2.26e-05	0.000289	3.54	0.000197	Col11a1/Igf1/Scn1a/Grin2b/Serpine2/Cxcl12/Kit/Htr2a/Fyn/Piezo2	10
GO:0007266	Rho protein signal transduction	BP	0.13	2.3e-05	0.000294	3.53	2e-04	Adra1a/Nrp1/Cdh2/Lpar4/Arhgef25/Cdh13/Apoe/Agtr1a/Rasip1/Eps8l1/Ednra/Pecam1/Arap3/Arrb1/Heg1/Dlc1/Net1/Cdc42ep5	18
GO:0048638	regulation of developmental growth	BP	0.0896	2.32e-05	0.000294	3.53	2e-04	Gli1/Map2/Sema5a/Ar/Cacna1c/Col14a1/H19/Nog/Igf1/Tbx2/Sema5b/Cpne5/Nkd1/Acacb/Sema7a/Nrp1/Fn1/Mef2c/Cxcl12/Hopx/Flvcr1/Gamt/Plcb1/Flt3/Apoe/Igf2/Sema3g/Slc23a2/Foxs1/Epha7/Cacng7/Ptch1/Pi16/Stat5b/Sema6a/Lats2	36
GO:0032943	mononuclear cell proliferation	BP	0.0944	2.32e-05	0.000294	3.53	2e-04	Ihh/Lef1/Igf1/Cd44/Mef2c/Cxcl12/Mapk8ip1/Dock2/Flt3/Tnfsf13b/Prdm1/Cd1d1/Msn/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Satb1/Pde5a/Fyn/H2-Aa/Stat5b/Zap70/Impdh1/Dlg5/Il12rb1	32
GO:0097061	dendritic spine organization	BP	0.149	2.32e-05	0.000294	3.53	2e-04	Nlgn1/Lrrk2/Grin2b/Ppfia2/Dock10/Kif1a/Abi2/Nlgn3/Apoe/Caprin2/Fyn/Bhlhb9/Dlg4/Cux2/Ngef	15
GO:0010463	mesenchymal cell proliferation	BP	0.193	2.36e-05	0.000297	3.53	0.000202	Ihh/Wnt11/Kdr/Tbx2/Gpc3/Foxf1/Zeb1/Osr1/Dchs1/Fat4/Ptn	11
GO:1902904	negative regulation of supramolecular fiber organization	BP	0.118	2.36e-05	0.000297	3.53	0.000202	Kank4/Map2/Evl/Phldb2/Tmod2/Pfn2/Cdh5/Coro1a/Rp1/Tubb4a/Apoe/Arhgap6/Tmeff2/Emilin1/Pecam1/Scin/Dysf/Arhgap28/Ttbk2/Dlc1/Plekhh2	21
GO:0010721	negative regulation of cell development	BP	0.112	2.42e-05	0.000304	3.52	0.000207	Prtg/Efnb3/Map2/Sema5a/Nog/Igf1/Sema5b/Sema7a/Nrp1/Tert/Ednrb/Dab1/Id4/Postn/Thy1/Trpc6/Daam2/Sema3g/Epha7/Nfatc4/Syngap1/Sema6a/Ptn	23
GO:0048565	digestive tract development	BP	0.135	2.47e-05	0.00031	3.51	0.000211	Stra6/Ihh/Sfrp2/Clmp/Pkdcc/Tbx2/Ednrb/Foxf1/Gli3/Tcf21/Prdm1/Kit/Pcsk5/Dchs1/Fat4/Dact1/Stx2	17
GO:0009952	anterior/posterior pattern specification	BP	0.106	2.5e-05	0.000313	3.51	0.000213	Sfrp2/Lef1/Hoxd10/Hoxd11/Nog/Zeb2/Hoxa11/Gpc3/Hoxd9/Hoxa10/Foxf1/Hoxd8/Hoxd4/Tshz1/Gdf11/Gli3/Lfng/Hoxd3/Tbx3/Heyl/Pcsk5/Hoxa9/Hipk2/Osr1/Ets2	25
GO:0032233	positive regulation of actin filament bundle assembly	BP	0.176	2.61e-05	0.000325	3.49	0.000221	Wnt11/Evl/Ccdc88a/Nrp1/Fermt2/Pfn2/Ppm1f/Limch1/Nox4/Arhgef15/Ppm1e/Ccn2	12
GO:0034767	positive regulation of ion transmembrane transport	BP	0.114	2.61e-05	0.000325	3.49	0.000221	Cacna1c/Tcaf1/Drd4/Cacna2d1/Myo5a/Cxcr3/Edn3/Ank2/Plcb1/Thy1/Trpc6/Nlgn3/Aplnr/Cracr2a/Agtr1a/Ednra/Stac2/Asph/Pkd2/Gstm7/Abcb1a/Cacnb4	22
GO:0140058	neuron projection arborization	BP	0.267	2.61e-05	0.000325	3.49	0.000221	Nlgn1/Nrp1/Lrrk2/Lrp2/Myo9a/Dlg4/Ptn/Ntng1	8
GO:0003382	epithelial cell morphogenesis	BP	0.208	2.74e-05	0.00034	3.47	0.000231	Ihh/Ar/Stc1/Rilpl1/Palld/Pecam1/Col15a1/Heg1/Arhgef26/Col18a1	10
GO:0042060	wound healing	BP	0.0909	2.85e-05	0.000352	3.45	0.000239	Cd109/Kdr/Nog/Igf1/Evl/Ddr2/Tfpi/Abat/Phldb2/Cd44/Fermt2/Fn1/Fkbp10/Serpine2/Plpp3/Procr/Ccm2l/Tsku/Apoe/Syt7/Tmeff2/Ndnf/Pecam1/Pros1/Cnn2/Dysf/Abi3bp/Ptger3/Clec7a/St3gal4/Rab27a/Smpd1/Cav1/Cldn1	34
GO:2000807	regulation of synaptic vesicle clustering	BP	0.5	2.88e-05	0.000355	3.45	0.000241	Nlgn1/Cdh2/Nlgn3/Magi2/Pcdh17	5
GO:0001656	metanephros development	BP	0.154	2.88e-05	0.000355	3.45	0.000241	Hoxd11/Hoxa11/Gpc3/Id3/Osr2/Gdf11/Gli3/Tcf21/Tshz3/Ptch1/Osr1/Fat4/Dlg5/Itga8	14
GO:0002062	chondrocyte differentiation	BP	0.139	2.89e-05	0.000355	3.45	0.000241	Col11a1/Ihh/Sfrp2/Mdk/Hoxd11/Pkdcc/Hoxa11/Mef2c/Osr2/Gli3/Pth1r/Wnt9a/Adamts7/Ltbp3/Osr1/Ccn2	16
GO:0045879	negative regulation of smoothened signaling pathway	BP	0.231	2.91e-05	0.000356	3.45	0.000242	Gli1/Hhip/Kif7/Gpc3/Serpine2/Gli3/Gpr161/Enpp1/Ptch1	9
GO:0051961	negative regulation of nervous system development	BP	0.12	2.94e-05	0.00036	3.44	0.000245	Prtg/Efnb3/Map2/Sema5a/Nog/Sema5b/Sema7a/Nrp1/Tert/Dab1/Id4/Thy1/Trpc6/Daam2/Sema3g/Epha7/Nfatc4/Syngap1/Sema6a/Ptn	20
GO:0060249	anatomical structure homeostasis	BP	0.0945	3.02e-05	0.000368	3.43	0.00025	Tex15/Ihh/Angpt1/Col14a1/Kdr/Tub/Nos3/P2rx2/Calca/Flt3/Pth1r/Pbld2/Coro1a/Ldb2/Rp1/Tnfrsf11b/Nox4/Cd38/Enpp1/Bdkrb2/Crocc/Lpcat1/Ltbp3/Rcn3/Cldn5/Ccn2/Iqcb1/Akt3/Abcb1a/Bbs1/Large1	31
GO:0060041	retina development in camera-type eye	BP	0.116	3.03e-05	0.000369	3.43	0.000251	Ndp/Ihh/Cyp1b1/Sdk2/Tub/Celf4/Lamc3/Nrp1/Arl6/Obsl1/Thy1/Tgif2/Ptprm/Rp1/Arhgef15/Rorb/Lpcat1/Hipk2/Fat3/Nphp1/Ptn	21
GO:0032271	regulation of protein polymerization	BP	0.11	3.04e-05	0.00037	3.43	0.000251	Kank4/Map2/Evl/Hcls1/Tmod2/Pfn2/Icam1/Cdh5/Coro1a/Esam/Tubb4a/Daam2/Pecam1/Scin/Nckap1l/Slain1/Nin/Bin1/Arhgap28/Cdc42ep5/Cav1/Cyfip2/Tppp	23
GO:0043523	regulation of neuron apoptotic process	BP	0.0989	3.19e-05	0.000386	3.41	0.000262	Ptprz1/Angpt1/Mdk/Kdr/Agap2/Nrp1/Tert/Bok/Mef2c/Pcdhgc3/Itga1/Coro1a/Il27ra/Grik2/Apoe/Kcnma1/Ndnf/Arrb1/Hipk2/Epha7/Kcnip3/Nfatc4/Arrb2/Fyn/Bhlhb9/Syngap1/Nes/Cacna1a	28
GO:0001574	ganglioside biosynthetic process	BP	0.375	3.2e-05	0.000386	3.41	0.000262	St8sia2/St8sia4/St6galnac4/St3gal2/St8sia6/St6galnac6	6
GO:0072498	embryonic skeletal joint development	BP	0.375	3.2e-05	0.000386	3.41	0.000262	Ihh/Hoxd11/Nog/Hoxa11/Osr2/Osr1	6
GO:0098659	inorganic cation import across plasma membrane	BP	0.138	3.22e-05	0.000386	3.41	0.000263	Kcnj3/Cacna1c/Kcnd3/Slc12a8/Slc8a1/Slc24a4/Slc9a7/Cacna1e/Slc8a3/Nalf1/Agtr1a/Slc9a5/Fyn/Slc12a4/Atp1a2/Cacna1a	16
GO:0099587	inorganic ion import across plasma membrane	BP	0.138	3.22e-05	0.000386	3.41	0.000263	Kcnj3/Cacna1c/Kcnd3/Slc12a8/Slc8a1/Slc24a4/Slc9a7/Cacna1e/Slc8a3/Nalf1/Agtr1a/Slc9a5/Fyn/Slc12a4/Atp1a2/Cacna1a	16
GO:0060326	cell chemotaxis	BP	0.0955	3.29e-05	0.000393	3.41	0.000267	Cxcl15/Hgf/Sema5a/Lef1/Mdk/Kdr/Cyp7b1/Ptpro/Nrp1/Ednrb/Prkd1/Cxcr3/Cxcl12/Jam3/Edn3/Itga1/Calca/Coro1a/Kit/Vegfc/Agtr1a/Ednra/Xcl1/Nckap1l/Tnfaip6/Dysf/Xcr1/Arrb2/Mpp1/Ptn	30
GO:0019722	calcium-mediated signaling	BP	0.112	3.32e-05	0.000396	3.4	0.000269	Sgcd/Kdr/Nr5a2/Igf1/Slc8a1/Drd4/Ednrb/Slc24a4/Lrrk2/Cxcr3/Cdh13/Ptgfr/Ank2/Adgrl1/Itgal/Agtr1a/Cmya5/Xcr1/Nfatc4/Atp2b4/Zap70/Lat	22
GO:0001837	epithelial to mesenchymal transition	BP	0.123	3.33e-05	0.000397	3.4	0.00027	Sfrp2/Lef1/Mdk/Wnt11/Nog/Mark1/Phldb2/Fermt2/Erg/Has2/Loxl3/Epha3/Tbx3/Heyl/Ednra/Snai1/Spred3/Il17rd/Dlg5	19
GO:1903829	positive regulation of protein localization	BP	0.0835	3.34e-05	0.000397	3.4	0.00027	Igf1/Nlgn1/Abat/Tcaf1/Ccdc88a/Hcls1/Fermt2/Gnai1/Tert/Ano1/Myo5a/Ptp4a3/Prkd1/Tek/Gli3/Lrp2/Rab34/Msn/Epha3/Nlgn3/Prr5l/Vegfc/Cd38/Pecam1/Tmem35a/Crocc/Tnfaip6/Stac2/Arrb1/Asph/Abcg1/Dzip1/Frmd4a/Mgat3/Fyn/Wipf1/Dlg4/Atp2b4/Ptn/Nkd2/Cacnb4	41
GO:0032535	regulation of cellular component size	BP	0.0891	3.35e-05	0.000397	3.4	0.00027	Kank4/Map2/Sema5a/Evl/Sema5b/Slc12a8/Hcls1/Sema7a/Nrp1/Tmod2/Fn1/Pfn2/Icam1/Cxcl12/Coro1a/Esam/Sh3bp1/Apoe/Kcnma1/Daam2/Pecam1/Scin/Sema3g/Nckap1l/Bin1/Epha7/Arhgap28/Aqp11/Slc12a4/Akt3/Sema6a/Cdc42ep5/C1qtnf9/Cyfip2/Plekhh2	35
GO:0001952	regulation of cell-matrix adhesion	BP	0.132	3.36e-05	0.000398	3.4	0.000271	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Cdh13/Postn/Thy1/Epha3/Ppm1f/Limch1/Vegfc/Arhgap6/Pcsk5/Dlc1/Efemp2	17
GO:0050771	negative regulation of axonogenesis	BP	0.171	3.53e-05	0.000416	3.38	0.000283	Efnb3/Map2/Sema5a/Sema5b/Sema7a/Nrp1/Dab1/Thy1/Sema3g/Epha7/Syngap1/Sema6a	12
GO:0086003	cardiac muscle cell contraction	BP	0.171	3.53e-05	0.000416	3.38	0.000283	Sgcd/Cacna1c/Kcnd3/Scn4b/Scn1a/Cacna2d1/Stc1/Ank2/Bin1/Cacna1h/Atp1a2/Cav1	12
GO:0098657	import into cell	BP	0.104	3.56e-05	0.000418	3.38	0.000284	Kcnj3/Slc1a3/Acsl6/Cacna1c/Itga4/Slc6a2/Kcnd3/Slc12a8/Slc8a1/Slc24a4/Slc9a7/Slc7a2/Cacna1e/Slc8a3/Lrp2/Nalf1/Slc29a1/Agtr1a/Slc9a5/Fyn/Slc12a4/Atp1a2/Steap4/Acsl1/Cacna1a	25
GO:0048732	gland development	BP	0.084	3.6e-05	0.000422	3.37	0.000287	Gli1/Stra6/Hgf/Ar/Lef1/Mdk/Agap2/Nog/Cyp7b1/Igf1/Tbx2/Cd44/Nrp1/Edaradd/Hoxd9/Areg/Mmp2/Foxf1/Id4/Serpine2/Gli3/Tcf21/Gdf7/Plxnd1/Msn/Cdkn1c/Hoxd3/Tbx3/Ednra/Igf2/Hoxa9/Pkd1/Ptch1/Pkd2/Stat5b/Asl/Ptn/Cav1/Edar/Cacnb4	40
GO:0009311	oligosaccharide metabolic process	BP	0.225	3.61e-05	0.000422	3.37	0.000287	St6gal2/St8sia2/St8sia4/B3galnt1/St6galnac4/St3gal2/St8sia6/St6galnac6/St3gal4	9
GO:0010634	positive regulation of epithelial cell migration	BP	0.122	3.65e-05	0.000426	3.37	0.00029	Sema5a/Angpt1/Kdr/Igf1/Nos3/Nrp1/Ets1/Prkd1/Tek/Has2/Plpp3/Ppm1f/Jcad/Vegfc/Igf2/Hdac9/Akt3/Adgra2/Mapre2	19
GO:0060996	dendritic spine development	BP	0.131	3.72e-05	0.000433	3.36	0.000295	Nlgn1/Lrrk2/Mef2c/Ppfia2/D16Ertd472e/Dock10/Kif1a/Abi2/Nlgn3/Apoe/Caprin2/Bhlhb9/Dlg4/Cux2/Palm/Dlg5/Ngef	17
GO:0050905	neuromuscular process	BP	0.111	3.88e-05	0.00045	3.35	0.000306	Ankfn1/Stra6/Slc1a3/Hoxd10/Jph4/Aph1b/Scn1a/Myo5a/Grin2b/Slc8a3/Tshz3/Glrb/Nlgn3/Npas3/Kcnma1/Prrt2/Ednra/Foxs1/Stac2/Hipk2/Dlg4/Cacna1a	22
GO:0098815	modulation of excitatory postsynaptic potential	BP	0.183	3.9e-05	0.000452	3.34	0.000307	Nlgn1/Celf4/Drd4/Stx1b/Lrrk2/Grin2b/Tbc1d24/Slc8a3/Nlgn3/Dlg4/Cux2	11
GO:0051279	regulation of release of sequestered calcium ion into cytosol	BP	0.159	3.98e-05	0.000461	3.34	0.000314	Slc8a1/Myo5a/Prkd1/Cxcr3/Ank2/Thy1/Coro1a/Aplnr/Ednra/Asph/Selenon/Pkd2/Gstm7	13
GO:0030217	T cell differentiation	BP	0.096	4.03e-05	0.000465	3.33	0.000316	Ihh/Lef1/Mdk/Cd83/Cd44/Itk/Cd3g/Pik3r6/Gli3/Dock2/Flt3/Zeb1/Prdm1/Cd1d1/Jag2/Lfng/Loxl3/Kit/Cracr2a/Enpp1/Sox12/Nckap1l/Satb1/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il2rg	29
GO:0006665	sphingolipid metabolic process	BP	0.125	4.1e-05	0.000472	3.33	0.000321	St8sia2/St8sia4/Elovl4/Agk/Cerkl/Sptlc3/Cers4/Plpp3/St6galnac4/St3gal2/Kit/St8sia6/Degs2/Abca8b/B3gnt5/St6galnac6/Plpp1/Smpd1	18
GO:0045582	positive regulation of T cell differentiation	BP	0.142	4.16e-05	0.000478	3.32	0.000325	Ihh/Lef1/Mdk/Cd83/Pik3r6/Gli3/Cd1d1/Sox12/Nckap1l/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il2rg	15
GO:0051899	membrane depolarization	BP	0.149	4.18e-05	0.000479	3.32	0.000326	Grik1/Cacna1c/Kdr/Scn4b/Scn1a/Bok/Cacna2d1/Lrrk2/Scn2a/Fhl1/Cacna1h/Scn3a/Cav1/Cacna1a	14
GO:0061351	neural precursor cell proliferation	BP	0.111	4.19e-05	0.000479	3.32	0.000326	Gli1/Ptprz1/Acsl6/Hhip/Lef1/Mdk/Nog/Igf1/Zeb2/Cdh2/Smarca1/Lrrk2/Id4/Zfp423/Gli3/Lrp2/Kif1a/Eml1/Vegfc/Nes/Ptn/Bbs1	22
GO:0060048	cardiac muscle contraction	BP	0.129	4.53e-05	0.000517	3.29	0.000352	Sgcd/Cacna1c/Kcnd3/Adra1a/Slc8a1/Scn4b/Scn1a/Cacna2d1/Stc1/Ank2/Myl3/Bin1/Pde5a/Cacna1h/Ccn2/Atp1a2/Cav1	17
GO:0006643	membrane lipid metabolic process	BP	0.113	4.55e-05	0.000519	3.28	0.000353	Cyp1b1/St8sia2/St8sia4/Elovl4/Agk/Cerkl/Sptlc3/Cers4/Plpp3/St6galnac4/St3gal2/Kit/St8sia6/Degs2/Sccpdh/Abca8b/B3gnt5/St6galnac6/Plpp1/St3gal4/Smpd1	21
GO:0006820	anion transport	BP	0.0823	4.6e-05	0.000523	3.28	0.000356	Slc1a3/Car4/Grik1/Pla2g10/Slc13a5/Slc2a3/Slc12a8/Abat/Tcaf1/Drd4/Ano1/Slc7a2/Grin2b/Stc1/Abcg2/Slc36a4/Ano2/Lrp2/Htr1b/Ttyh2/Slc6a15/Glrb/Gabra4/Enpp1/Bdkrb2/Slc23a2/Sfxn5/Slco4c1/Ptger3/Nfkbie/Slc4a3/Slc38a1/Slc12a4/Clca2/Abcb1a/Abcc5/Abcg3/Gabbr1/Slc4a8/Cacna1a/Cacnb4	41
GO:0014031	mesenchymal cell development	BP	0.147	4.71e-05	0.000534	3.27	0.000364	Sema5a/Sema5b/Zeb2/Sema7a/Nrp1/Cdh2/Ednrb/Fn1/Edn3/Heyl/Ednra/Sema3g/Kitl/Sema6a	14
GO:0001886	endothelial cell morphogenesis	BP	0.353	4.77e-05	0.00054	3.27	0.000367	Stc1/Pecam1/Col15a1/Heg1/Arhgef26/Col18a1	6
GO:1905564	positive regulation of vascular endothelial cell proliferation	BP	0.353	4.77e-05	0.00054	3.27	0.000367	Mdk/Itga4/Igf1/Igf2/Apln/Akt3	6
GO:0046578	regulation of Ras protein signal transduction	BP	0.109	4.88e-05	0.00055	3.26	0.000374	Igf1/Adra1a/Nrp1/Cdh2/Rasa3/Lpar4/Arhgef25/Dock2/Sh2b2/Syde1/Sh3bp1/Apoe/Rasip1/Eps8l1/Arap3/Kitl/Arrb1/Heg1/Dlc1/Net1/Syngap1/Mapre2	22
GO:0014812	muscle cell migration	BP	0.133	4.91e-05	0.000552	3.26	0.000376	Cyp1b1/Mdk/Igf1/Ddr2/Drd4/Tert/Mef2c/Myo5a/Has2/Adamts1/Postn/Nox4/Enpp1/Pcsk5/Net1/Plekho1	16
GO:0007612	learning	BP	0.112	4.93e-05	0.000552	3.26	0.000376	Stra6/Cacna1c/Nog/Jph4/Drd4/Chst10/Grin2b/B4galt2/Pde1b/Adcy3/Shank2/Cacna1e/Slc8a3/Eif2ak4/Kit/Nlgn3/Atp1a2/Brsk1/Syngap1/Ptn/Ddhd2	21
GO:0042129	regulation of T cell proliferation	BP	0.112	4.93e-05	0.000552	3.26	0.000376	Ihh/Igf1/Cd44/Mapk8ip1/Tnfsf13b/Cd1d1/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Havcr2/Igf2/Xcl1/Nckap1l/Pde5a/H2-Aa/Stat5b/Zap70/Dlg5/Il12rb1	21
GO:0046467	membrane lipid biosynthetic process	BP	0.128	4.99e-05	0.000558	3.25	0.00038	St8sia2/St8sia4/Elovl4/Agk/Cerkl/Sptlc3/Cers4/St6galnac4/St3gal2/St8sia6/Degs2/Sccpdh/Abca8b/B3gnt5/St6galnac6/St3gal4/Smpd1	17
GO:0045588	positive regulation of gamma-delta T cell differentiation	BP	0.455	5.09e-05	0.000568	3.25	0.000386	Lef1/Nckap1l/Stat5b/Gimap5/Gimap3	5
GO:0046645	positive regulation of gamma-delta T cell activation	BP	0.455	5.09e-05	0.000568	3.25	0.000386	Lef1/Nckap1l/Stat5b/Gimap5/Gimap3	5
GO:0002695	negative regulation of leukocyte activation	BP	0.109	5.26e-05	0.000584	3.23	0.000397	Ihh/Mdk/Cd44/Foxf1/Gli3/Flt3/Prdm1/Loxl3/Btla/H2-Ab1/Havcr2/Cd200/Nckap1l/Pde5a/Cd84/Fgr/H2-Aa/Gimap5/Dlg5/Gimap3/Clnk/Nr1h3	22
GO:0006941	striated muscle contraction	BP	0.115	5.31e-05	0.000588	3.23	4e-04	Sgcd/Cacna1c/Kcnd3/Adra1a/Slc8a1/Scn4b/Scn1a/Cacna2d1/Stc1/Ank2/Slc8a3/Myl3/Bin1/Stac2/Ryr3/Pde5a/Cacna1h/Ccn2/Atp1a2/Cav1	20
GO:1903034	regulation of response to wounding	BP	0.115	5.31e-05	0.000588	3.23	4e-04	Mdk/Cd109/Ddr2/Tfpi/Abat/Phldb2/Fermt2/Serpine2/Plpp3/Apoe/Pros1/Rtn4rl1/Neo1/Ptger3/Clec7a/Xylt1/St3gal4/Ptn/Cav1/Cldn1	20
GO:0010171	body morphogenesis	BP	0.177	5.35e-05	0.000591	3.23	0.000402	Stra6/Ihh/Lef1/Nog/Crispld1/Phldb2/Gpc3/Mmp2/Flvcr1/Twist2/Asph	11
GO:0060997	dendritic spine morphogenesis	BP	0.164	5.43e-05	0.000598	3.22	0.000407	Nlgn1/Lrrk2/Ppfia2/Dock10/Kif1a/Abi2/Nlgn3/Caprin2/Bhlhb9/Dlg4/Cux2/Ngef	12
GO:0017015	regulation of transforming growth factor beta receptor signaling pathway	BP	0.132	5.44e-05	0.000598	3.22	0.000407	Cd109/Zeb2/Npnt/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Hipk2/Nrros/Zfyve9/Il17rd/Lats2/Cav1/Itga8	16
GO:0038084	vascular endothelial growth factor signaling pathway	BP	0.214	5.45e-05	0.000599	3.22	0.000407	Kdr/Nrp1/Ptp4a3/Prkd1/Jcad/Vegfc/Tcf4/Sema6a/Adgra2	9
GO:0062149	detection of stimulus involved in sensory perception of pain	BP	0.242	5.53e-05	0.000605	3.22	0.000412	Scn1a/Ano1/Grin2b/Cxcl12/Calca/Htr2a/Arrb2/Fyn	8
GO:0150117	positive regulation of cell-substrate junction organization	BP	0.242	5.53e-05	0.000605	3.22	0.000412	Kdr/Nrp1/Fermt2/Col16a1/Tek/Thy1/Ppm1f/Mapre2	8
GO:1902105	regulation of leukocyte differentiation	BP	0.0929	5.55e-05	0.000606	3.22	0.000412	Ihh/Lef1/Mdk/Cd83/Cd44/Hcls1/Inpp4b/Pik3r6/Lrrc17/Gli3/Calca/Flt3/Zeb1/Prdm1/Cd1d1/Loxl3/Tnfrsf11b/Sox12/Zbtb46/Nckap1l/Tal1/Kitl/Tnfaip6/Rassf2/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il2rg	30
GO:0061005	cell differentiation involved in kidney development	BP	0.192	5.69e-05	0.000618	3.21	0.000421	Ptpro/Ednrb/Mef2c/Gli3/Tcf21/Tshz3/Ednra/Ptch1/Osr1/Fat4	10
GO:0061756	leukocyte adhesion to vascular endothelial cell	BP	0.192	5.69e-05	0.000618	3.21	0.000421	Mdk/Itga4/Chst2/Ets1/Itgb7/Icam1/Podxl2/Cxcl12/Sele/St3gal4	10
GO:0060998	regulation of dendritic spine development	BP	0.153	5.87e-05	0.000636	3.2	0.000433	Nlgn1/Mef2c/Ppfia2/D16Ertd472e/Kif1a/Nlgn3/Apoe/Caprin2/Bhlhb9/Cux2/Palm/Dlg5/Ngef	13
GO:0001570	vasculogenesis	BP	0.144	5.96e-05	0.000644	3.19	0.000438	Angpt1/Kdr/Nrp1/Foxf1/Tek/Has2/Aplnr/Enpp1/Rasip1/Tie1/Gjc1/Heg1/Egfl7/Cav1	14
GO:0007202	activation of phospholipase C activity	BP	0.28	5.98e-05	0.000644	3.19	0.000438	Adra1a/Itk/Arhgap6/Sele/Adcyap1r1/Htr2a/Dlc1	7
GO:0101023	vascular endothelial cell proliferation	BP	0.28	5.98e-05	0.000644	3.19	0.000438	Mdk/Itga4/Igf1/Mef2c/Igf2/Apln/Akt3	7
GO:1905562	regulation of vascular endothelial cell proliferation	BP	0.28	5.98e-05	0.000644	3.19	0.000438	Mdk/Itga4/Igf1/Mef2c/Igf2/Apln/Akt3	7
GO:0045621	positive regulation of lymphocyte differentiation	BP	0.131	6.02e-05	0.000646	3.19	0.00044	Ihh/Lef1/Mdk/Cd83/Pik3r6/Gli3/Prdm1/Cd1d1/Sox12/Nckap1l/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il2rg	16
GO:0006022	aminoglycan metabolic process	BP	0.136	6.44e-05	0.000687	3.16	0.000468	Angpt1/Cd44/Spock2/Ednrb/Has2/Egflam/Mamdc2/Chst1/Ednra/Ndnf/Tnfaip6/Bgn/Xylt1/Dse/Habp4	15
GO:0016525	negative regulation of angiogenesis	BP	0.136	6.44e-05	0.000687	3.16	0.000468	Hhip/Tek/Cxcr3/Adamts1/Vash1/Ptprm/Minar1/Ecscr/Emilin1/Tie1/Tcf4/Cldn5/Atp2b4/Sema6a/Ptn	15
GO:0014065	phosphatidylinositol 3-kinase signaling	BP	0.125	6.63e-05	0.000704	3.15	0.000479	Myo16/Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Hcls1/Fn1/Serpine2/Tek/Ppp1r16b/Prr5l/Htr2a/Prex2/Fyn/Fgr	17
GO:0010874	regulation of cholesterol efflux	BP	0.209	6.64e-05	0.000704	3.15	0.000479	Pla2g10/Pltp/Apoe/Abca5/Ptch1/Abcg1/Abca8b/Cav1/Nr1h3	9
GO:0085029	extracellular matrix assembly	BP	0.209	6.64e-05	0.000704	3.15	0.000479	Ihh/Phldb2/Fkbp10/Has2/Emilin1/Tie1/Ltbp3/Efemp2/Ntng1	9
GO:0048041	focal adhesion assembly	BP	0.151	6.65e-05	0.000704	3.15	0.000479	Kdr/Phldb2/Nrp1/Fermt2/Col16a1/Tek/Thsd1/Thy1/Epha3/Ppm1f/Limch1/Arhgap6/Dlc1	13
GO:0098739	import across plasma membrane	BP	0.11	6.71e-05	0.00071	3.15	0.000483	Kcnj3/Slc1a3/Acsl6/Cacna1c/Kcnd3/Slc12a8/Slc8a1/Slc24a4/Slc9a7/Slc7a2/Cacna1e/Slc8a3/Lrp2/Nalf1/Agtr1a/Slc9a5/Fyn/Slc12a4/Atp1a2/Acsl1/Cacna1a	21
GO:0042492	gamma-delta T cell differentiation	BP	0.333	6.9e-05	0.000724	3.14	0.000493	Lef1/Jag2/Nckap1l/Stat5b/Gimap5/Gimap3	6
GO:0097091	synaptic vesicle clustering	BP	0.333	6.9e-05	0.000724	3.14	0.000493	Syn2/Nlgn1/Cdh2/Nlgn3/Magi2/Pcdh17	6
GO:0099150	regulation of postsynaptic specialization assembly	BP	0.333	6.9e-05	0.000724	3.14	0.000493	Gap43/Ptprd/Lrrc4b/Nptx1/Nptxr/Arhgef9	6
GO:0002064	epithelial cell development	BP	0.102	6.92e-05	0.000724	3.14	0.000493	Ihh/Ar/Cdh2/Ednrb/Icam1/Stc1/Plcb1/Cdh5/Prdm1/Msn/Abi2/Ppp1r16b/Robo4/Rilpl1/Palld/Ednra/Pecam1/Col15a1/Heg1/Arhgef26/Cldn5/Abcb1a/Col18a1/Cldn1	24
GO:0050654	chondroitin sulfate proteoglycan metabolic process	BP	0.235	6.97e-05	0.000727	3.14	0.000494	Igf1/Spock2/Egflam/Mamdc2/Ndnf/Bgn/Xylt1/Dse	8
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	BP	0.235	6.97e-05	0.000727	3.14	0.000494	Mdk/Itga4/Chst2/Ets1/Icam1/Cxcl12/Sele/St3gal4	8
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	BP	0.16	7.14e-05	0.00074	3.13	0.000503	Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Hcls1/Fn1/Tek/Prr5l/Fyn/Fgr	12
GO:0042982	amyloid precursor protein metabolic process	BP	0.16	7.14e-05	0.00074	3.13	0.000503	Itm2a/Igf1/Aph1b/Rtn1/Soat1/Slc2a13/Apoe/Nsg1/Bin1/Abcg1/Adam19/Tmcc2	12
GO:0097120	receptor localization to synapse	BP	0.16	7.14e-05	0.00074	3.13	0.000503	Gpc6/Nlgn1/Lrrc7/Cep112/Stx1b/Nptx1/Dlg2/Nptxr/Magi2/Nsg1/Cacng7/Dlg4	12
GO:0014911	positive regulation of smooth muscle cell migration	BP	0.172	7.24e-05	0.000748	3.13	0.000509	Cyp1b1/Mdk/Igf1/Ddr2/Tert/Myo5a/Has2/Adamts1/Postn/Nox4/Pcsk5	11
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	BP	0.172	7.24e-05	0.000748	3.13	0.000509	Igf1/Ddr2/Drd4/Tert/Mmp2/Mef2c/Adamts1/Htr1b/Rgs5/Apln/Efemp2	11
GO:1903844	regulation of cellular response to transforming growth factor beta stimulus	BP	0.129	7.34e-05	0.000756	3.12	0.000514	Cd109/Zeb2/Npnt/Pbld2/Zeb1/Cdkn1c/Tsku/Emilin1/Spred3/Hipk2/Nrros/Zfyve9/Il17rd/Lats2/Cav1/Itga8	16
GO:0014033	neural crest cell differentiation	BP	0.141	7.48e-05	0.000769	3.11	0.000523	Sema5a/Sema5b/Zeb2/Sema7a/Nrp1/Cdh2/Ednrb/Fn1/Mef2c/Edn3/Ednra/Sema3g/Kitl/Sema6a	14
GO:0060541	respiratory system development	BP	0.0974	7.84e-05	0.000804	3.09	0.000547	Gli1/Stra6/Hhip/Lef1/Kdr/Nog/Igf1/Pkdcc/Tbx2/Nos3/Edaradd/Gpc3/Ano1/Foxf1/Hopx/Gli3/Tcf21/Tshz3/Loxl3/Mgp/Ltbp3/Heg1/Rcn3/Selenon/Ccn2/Dlg5	26
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	BP	0.269	7.89e-05	0.000807	3.09	0.000549	Mdk/Itga4/Chst2/Ets1/Icam1/Sele/St3gal4	7
GO:0008064	regulation of actin polymerization or depolymerization	BP	0.115	7.89e-05	0.000807	3.09	0.000549	Kank4/Sema5a/Evl/Hcls1/Tmod2/Pfn2/Icam1/Coro1a/Esam/Sh3bp1/Daam2/Pecam1/Scin/Nckap1l/Bin1/Arhgap28/Cdc42ep5/Cyfip2/Plekhh2	19
GO:0007369	gastrulation	BP	0.112	7.92e-05	0.000808	3.09	0.00055	Sfrp2/Lef1/Wnt11/Nog/Phldb2/Hoxa11/Fn1/Foxf1/Osr2/Plpp3/Tgif2/Aplnr/Snai1/Tal1/Col5a2/Osr1/Apln/Ets2/Dact1/Kif16b	20
GO:0002027	regulation of heart rate	BP	0.134	7.94e-05	0.000808	3.09	0.00055	Cacna1c/Kcnd3/Adra1a/Slc8a1/Scn4b/Ednrb/Cacna2d1/Cacna1e/Edn3/Ank2/Calca/Ednra/Bin1/Apln/Cav1	15
GO:2000181	negative regulation of blood vessel morphogenesis	BP	0.134	7.94e-05	0.000808	3.09	0.00055	Hhip/Tek/Cxcr3/Adamts1/Vash1/Ptprm/Minar1/Ecscr/Emilin1/Tie1/Tcf4/Cldn5/Atp2b4/Sema6a/Ptn	15
GO:0002040	sprouting angiogenesis	BP	0.128	8.09e-05	0.000821	3.09	0.000558	Sema5a/Angpt1/Lef1/Kdr/Nrp1/Tek/Cdh13/Ppp1r16b/Aplnr/Jcad/Vegfc/Agtr1a/Hdac9/Akt3/Sema6a/Adgra2	16
GO:0022408	negative regulation of cell-cell adhesion	BP	0.106	8.15e-05	0.000826	3.08	0.000562	Ihh/Lef1/Mdk/Abat/Cd44/Serpine2/Cxcl12/Gli3/Podxl/Loxl3/Ccm2l/Ppm1f/Btla/H2-Ab1/Havcr2/Nckap1l/Pde5a/Ptger3/H2-Aa/Gimap5/Dlg5/Gimap3	22
GO:0001954	positive regulation of cell-matrix adhesion	BP	0.169	8.39e-05	0.000848	3.07	0.000577	Kdr/Nrp1/Fermt2/Col16a1/Tek/Cdh13/Thy1/Ppm1f/Vegfc/Pcsk5/Efemp2	11
GO:0003151	outflow tract morphogenesis	BP	0.148	8.48e-05	0.000854	3.07	0.000581	Sfrp2/Wnt11/Ryr1/Nog/Tbx2/Nrp1/Mef2c/Lrp2/Plxnd1/Tbx3/Heyl/Ednra/Fzd2	13
GO:0006942	regulation of striated muscle contraction	BP	0.148	8.48e-05	0.000854	3.07	0.000581	Cacna1c/Adra1a/Slc8a1/Stc1/Ank2/Slc8a3/Myl3/Bin1/Pde5a/Cacna1h/Ccn2/Atp1a2/Cav1	13
GO:0048660	regulation of smooth muscle cell proliferation	BP	0.111	8.56e-05	0.000859	3.07	0.000584	Vipr2/Igf1/Ddr2/Nos3/Drd4/Npr3/Tert/Mmp2/Mef2c/Cdh13/Adamts1/Htr1b/Rgs5/Apoe/Irak4/Calcrl/Apln/Stat5b/Efemp2/Cav1	20
GO:0050906	detection of stimulus involved in sensory perception	BP	0.111	8.56e-05	0.000859	3.07	0.000584	Col11a1/Sema5a/Igf1/Sema5b/Scn1a/Slc24a4/Ano1/Grin2b/Serpine2/Cxcl12/Calca/Kit/Grik2/Ppef2/Htr2a/Plcb2/Arrb2/Fyn/Piezo2/Cacnb4	20
GO:1904738	vascular associated smooth muscle cell migration	BP	0.229	8.7e-05	0.000872	3.06	0.000593	Ddr2/Drd4/Tert/Mef2c/Myo5a/Adamts1/Enpp1/Pcsk5	8
GO:1901343	negative regulation of vasculature development	BP	0.133	8.8e-05	0.00088	3.06	0.000599	Hhip/Tek/Cxcr3/Adamts1/Vash1/Ptprm/Minar1/Ecscr/Emilin1/Tie1/Tcf4/Cldn5/Atp2b4/Sema6a/Ptn	15
GO:0070663	regulation of leukocyte proliferation	BP	0.0967	8.86e-05	0.000884	3.05	0.000602	Ihh/Igf1/Cd44/Mef2c/Mapk8ip1/Tnfsf13b/Prdm1/Cd1d1/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Kitl/Csf2rb/Pde5a/H2-Aa/Stat5b/Zap70/Dlg5/Il12rb1	26
GO:0032414	positive regulation of ion transmembrane transporter activity	BP	0.127	8.9e-05	0.000887	3.05	0.000603	Tcaf1/Drd4/Cacna2d1/Myo5a/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Ednra/Stac2/Asph/Pkd2/Gstm7/Abcb1a/Cacnb4	16
GO:0030323	respiratory tube development	BP	0.1	9.02e-05	0.000897	3.05	0.00061	Gli1/Stra6/Hhip/Kdr/Nog/Igf1/Pkdcc/Tbx2/Nos3/Gpc3/Foxf1/Hopx/Gli3/Tcf21/Tshz3/Loxl3/Mgp/Pcsk5/Ltbp3/Heg1/Rcn3/Selenon/Ccn2/Dlg5	24
GO:0045580	regulation of T cell differentiation	BP	0.114	9.28e-05	0.000918	3.04	0.000625	Ihh/Lef1/Mdk/Cd83/Cd44/Pik3r6/Gli3/Zeb1/Prdm1/Cd1d1/Loxl3/Sox12/Nckap1l/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il2rg	19
GO:0006029	proteoglycan metabolic process	BP	0.156	9.29e-05	0.000918	3.04	0.000625	Col11a1/Ihh/Igf1/Spock2/Chst10/Egflam/Mamdc2/Ndnf/Adamts7/Bgn/Xylt1/Dse	12
GO:0046635	positive regulation of alpha-beta T cell activation	BP	0.156	9.29e-05	0.000918	3.04	0.000625	Ihh/Cd83/Gli3/Cd1d1/H2-Ab1/Xcl1/Nckap1l/Gimap5/Zap70/Gimap3/Il12rb1/Il2rg	12
GO:0051098	regulation of binding	BP	0.0856	9.32e-05	0.00092	3.04	0.000626	Map2/Angpt1/Lef1/Itga4/Nog/Igf1/Zfp462/Runx1t1/Tert/Lrrk2/Hopx/Plxnd1/Lfng/Ccm2l/Apoe/Caprin2/Zc4h2/Twist2/Arrb1/Hipk2/Pkd1/Dysf/Arhgap28/Ttbk2/Nfatc4/Cldn5/Arrb2/Dzip1/Mfng/Habp4/Nes/Cav1/Dact1/Zfp90	34
GO:0001662	behavioral fear response	BP	0.182	9.37e-05	0.000923	3.03	0.000628	Ankfn1/Mdk/Drd4/Mef2c/Grin2b/Cacna1e/Grik2/Apoe/Gng7/Atp1a2	10
GO:0030098	lymphocyte differentiation	BP	0.0828	9.47e-05	0.000932	3.03	0.000634	Ihh/Lef1/Mdk/Cd83/Itm2a/Cd44/Il11ra1/Itk/Cd3g/Pik3r6/Gli3/Dock2/Flt3/Tnfsf13b/Dock10/Zeb1/Prdm1/Cd1d1/Jag2/Lfng/Loxl3/Kit/H2-Ab1/Cracr2a/Enpp1/Sox12/Irf8/Nckap1l/Satb1/Hdac9/H2-Aa/Stat5b/Gimap5/Zap70/Mfng/Gimap3/Il2rg	37
GO:0014032	neural crest cell development	BP	0.146	9.55e-05	0.000937	3.03	0.000638	Sema5a/Sema5b/Zeb2/Sema7a/Nrp1/Cdh2/Ednrb/Fn1/Edn3/Ednra/Sema3g/Kitl/Sema6a	13
GO:0008406	gonad development	BP	0.1	9.63e-05	0.000942	3.03	0.000641	Sfrp2/Angpt1/Ar/Kdr/Nos3/Fst/Hoxa11/Hoxa10/Mmp2/Icam1/Adamts1/Tcf21/Lrp2/Lfng/Kit/Hoxa9/Rhobtb3/Kitl/Tnfaip6/Arrb1/Osr1/Arrb2/Stat5b/Abcb1a	24
GO:0050918	positive chemotaxis	BP	0.2	9.67e-05	0.000942	3.03	0.000641	Sema5a/Angpt1/Kdr/Nrp1/Cxcl12/Cdh13/Lrp2/Coro1a/Vegfc	9
GO:0071825	protein-lipid complex subunit organization	BP	0.2	9.67e-05	0.000942	3.03	0.000641	Apob/Pla2g10/Soat1/Pltp/Apoe/Bin1/Abca5/Abcg1/Pcdhga3	9
GO:0006525	arginine metabolic process	BP	0.316	9.73e-05	0.000945	3.02	0.000643	Ddah1/Nos3/Fah/Atp2b4/Asl/Slc7a7	6
GO:0014051	gamma-aminobutyric acid secretion	BP	0.316	9.73e-05	0.000945	3.02	0.000643	Grik1/Abat/Htr1b/Gabbr1/Cacna1a/Cacnb4	6
GO:0003073	regulation of systemic arterial blood pressure	BP	0.126	9.79e-05	0.000949	3.02	0.000646	Ar/Kdr/Ddah1/Adra1a/Nos3/Ptpro/P2rx2/Adamts16/Ednrb/Enpep/Edn3/Calca/Rps6ka2/Postn/Agtr1a/Apln	16
GO:0072659	protein localization to plasma membrane	BP	0.0927	9.98e-05	0.000966	3.02	0.000657	Kcnb2/Ar/Pkdcc/Epb41l3/Ccdc88a/Cdh2/Efr3b/Arl6/Abi3/Myo5a/Gga2/Ank2/Rab34/Epha3/Ttc7b/Nfasc/Rilpl1/Nsg1/Stac2/Ptch1/Kcnip3/Dchs1/Tspan5/Atp2b4/Palm/Bbs1/Pid1/Nkd2	28
GO:0030832	regulation of actin filament length	BP	0.113	0.000101	0.000971	3.01	0.000661	Kank4/Sema5a/Evl/Hcls1/Tmod2/Pfn2/Icam1/Coro1a/Esam/Sh3bp1/Daam2/Pecam1/Scin/Nckap1l/Bin1/Arhgap28/Cdc42ep5/Cyfip2/Plekhh2	19
GO:0043547	positive regulation of GTPase activity	BP	0.0977	0.000102	0.000982	3.01	0.000668	Wnt11/Plxnb1/Rgs6/Rgs16/Rasgrp3/Fermt2/Garnl3/Arhgap45/Icam1/Rasgrp2/Arhgap25/Thy1/Dock10/Myo9a/Sh3bp1/Arhgef15/Arhgap6/Xcl1/Arap3/Bin1/Arhgef26/Net1/Gnb5/Ngef/Mapre2	25
GO:0030204	chondroitin sulfate metabolic process	BP	0.259	0.000103	0.000985	3.01	0.00067	Spock2/Egflam/Mamdc2/Ndnf/Bgn/Xylt1/Dse	7
GO:0002228	natural killer cell mediated immunity	BP	0.144	0.000107	0.00103	2.99	0.000699	Pik3r6/Coro1a/Cd226/Havcr2/Igf2/Arrb2/Stat5b/Gzmb/Gimap5/Gimap3/Rab27a/Cd96/Clnk	13
GO:0019915	lipid storage	BP	0.144	0.000107	0.00103	2.99	0.000699	Apob/Pla2g10/Acacb/Vstm2a/Mest/Soat1/Apoe/Enpp1/Dysf/Abcg1/Stat5b/Cav1/Nr1h3	13
GO:0045807	positive regulation of endocytosis	BP	0.125	0.000108	0.00103	2.99	0.000699	Angpt1/Nlgn1/Gpc3/Lrrk2/Lrp2/Apoe/Sele/Magi2/Nckap1l/Hip1/Bin1/Arrb1/Arrb2/Apln/Smpd1/Cav1	16
GO:0003203	endocardial cushion morphogenesis	BP	0.222	0.000108	0.00103	2.99	0.000699	Nog/Tbx2/Nos3/Aplnr/Tbx3/Heyl/Snai1/Dchs1	8
GO:0061001	regulation of dendritic spine morphogenesis	BP	0.179	0.00011	0.00104	2.98	0.00071	Nlgn1/Lrrk2/Ppfia2/Kif1a/Abi2/Nlgn3/Caprin2/Bhlhb9/Cux2/Ngef	10
GO:0021915	neural tube development	BP	0.106	0.000113	0.00107	2.97	0.000727	Sfrp2/Nog/Zeb2/Dzip1l/Sall2/Gli3/Lrp2/Gdf7/Ift57/Cecr2/Gpr161/Phgdh/Prickle1/Ptch1/Ipmk/Ttbk2/Dchs1/Dlc1/Fzd2/Rab23/Dact1	21
GO:0060323	head morphogenesis	BP	0.196	0.000116	0.00109	2.96	0.000743	Stra6/Ihh/Lef1/Nog/Crispld1/Mmp2/Flvcr1/Twist2/Asph	9
GO:1903170	negative regulation of calcium ion transmembrane transport	BP	0.196	0.000116	0.00109	2.96	0.000743	Drd4/Bin1/Dysf/Rrad/Ptger3/Pkd2/Gstm7/Atp1a2/Gnb5	9
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	BP	0.136	0.000116	0.00109	2.96	0.000743	Hgf/Angpt1/Kdr/Agap2/Plxnb1/Igf1/Hcls1/Fn1/Serpine2/Tek/Ppp1r16b/Prr5l/Fyn/Fgr	14
GO:0036293	response to decreased oxygen levels	BP	0.0988	0.000117	0.0011	2.96	0.000748	Kcnk3/Kcnd2/Ryr1/Kdr/Ddah1/Abat/Slc8a1/Cbs/P2rx2/Pygm/Tert/Mmp2/Grin2b/Tek/Slc8a3/Scn2a/Vegfc/Cd38/Kcnma1/Ednra/Ndnf/Cav1/Cpeb1/Hif3a	24
GO:0031099	regeneration	BP	0.115	0.000117	0.0011	2.96	0.00075	Gli1/Gap43/Hgf/Mdk/Igf1/Mmp2/Cxcl12/Hopx/Thy1/Matn2/Enpp1/Rtn4rl1/Dysf/Selenon/Neo1/Xylt1/Ptn/Large1	18
GO:0042476	odontogenesis	BP	0.124	0.000118	0.00111	2.96	0.000753	Wnt6/Lef1/Apcdd1/Fst/Edaradd/Slc24a4/Myo5a/Id3/Osr2/Gli3/Jag2/Tnfrsf11b/Enpp1/Ednra/Osr1/Edar	16
GO:0090101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.124	0.000118	0.00111	2.96	0.000753	Sfrp2/Cd109/Nog/Fst/Lrp2/Pbld2/Tsku/Magi2/Emilin1/Spred3/Tnfaip6/Hipk2/Nrros/Il17rd/Cav1/Tmprss6	16
GO:0015849	organic acid transport	BP	0.0903	0.000119	0.00112	2.95	0.000759	Slc1a3/Acsl6/Grik1/Pla2g10/Slc13a5/Abat/Drd4/Slc7a2/Grin2b/Abcg2/Rbp7/Slc36a4/Lrp2/Htr1b/Slc6a15/Apoe/Bdkrb2/Slc23a2/Sfxn5/Nfkbie/Slc38a1/Abcd2/Abcb1a/Slc7a7/Acsl1/Abcc5/Gabbr1/Cacna1a/Cacnb4	29
GO:0035023	regulation of Rho protein signal transduction	BP	0.143	0.00012	0.00112	2.95	0.000765	Adra1a/Nrp1/Cdh2/Lpar4/Arhgef25/Apoe/Rasip1/Eps8l1/Arap3/Arrb1/Heg1/Dlc1/Net1	13
GO:0010001	glial cell differentiation	BP	0.0965	0.000123	0.00114	2.94	0.000777	Gap43/Ptprz1/Lef1/Mdk/Nog/Igf1/Lamc3/Cdh2/Wasf3/Dab1/Id4/Serpine2/Gli3/Slc8a3/Plpp3/Nlgn3/Phgdh/Enpp1/Daam2/Tal1/Bin1/Nrros/Ptn/Tppp/Itgb4	25
GO:0051090	regulation of DNA-binding transcription factor activity	BP	0.0826	0.000123	0.00114	2.94	0.000778	Gli1/Ndp/Cyp1b1/4930447C04Rik/Acod1/Ar/Pla2g10/Eda2r/Ddr2/Hcls1/Id3/Icam1/Prkd1/Gli3/Eif2ak4/Plpp3/Ndn/Kit/Cth/Enpp1/Havcr2/Heyl/Cd200/Zc4h2/Rps6ka5/Foxs1/Arrb1/Hipk2/Pkd1/Ptch1/Nwd1/Cd84/Arrb2/Pkd2/Fzd2/Cav1	36
GO:0045137	development of primary sexual characteristics	BP	0.0984	0.000124	0.00116	2.94	0.000786	Sfrp2/Angpt1/Ar/Kdr/Nos3/Fst/Hoxa11/Hoxa10/Mmp2/Icam1/Adamts1/Tcf21/Lrp2/Lfng/Kit/Hoxa9/Rhobtb3/Kitl/Tnfaip6/Arrb1/Osr1/Arrb2/Stat5b/Abcb1a	24
GO:0031529	ruffle organization	BP	0.175	0.000128	0.00119	2.93	0.000807	Evl/Nlgn1/Cspg4/Aif1l/Pfn2/Icam1/Sh3bp1/Eps8l1/Arhgef26/Cav1	10
GO:0046849	bone remodeling	BP	0.135	0.000129	0.00119	2.92	0.000809	Ihh/Mdk/Inpp4b/Calca/Htr1b/Pth1r/Tnfrsf11b/Nox4/Cd38/Enpp1/Syt7/Ltbp3/Rassf2/Ptn	14
GO:0003272	endocardial cushion formation	BP	0.25	0.000132	0.00121	2.92	0.000822	Nog/Tbx2/Aplnr/Tbx3/Heyl/Snai1/Dchs1	7
GO:0033622	integrin activation	BP	0.25	0.000132	0.00121	2.92	0.000822	Fermt2/Fn1/Col16a1/Cxcl12/Jam3/Rasip1/Pcsk5	7
GO:0051894	positive regulation of focal adhesion assembly	BP	0.25	0.000132	0.00121	2.92	0.000822	Kdr/Nrp1/Fermt2/Col16a1/Tek/Thy1/Ppm1f	7
GO:0060272	embryonic skeletal joint morphogenesis	BP	0.385	0.000132	0.00121	2.92	0.000822	Hoxd11/Nog/Hoxa11/Osr2/Osr1	5
GO:0090022	regulation of neutrophil chemotaxis	BP	0.216	0.000132	0.00121	2.92	0.000822	Mdk/Jam3/Ednra/Xcl1/Nckap1l/Tnfaip6/Dysf/Mpp1	8
GO:0050670	regulation of lymphocyte proliferation	BP	0.098	0.000132	0.00121	2.92	0.000822	Ihh/Igf1/Cd44/Mef2c/Mapk8ip1/Tnfsf13b/Prdm1/Cd1d1/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Pde5a/H2-Aa/Stat5b/Zap70/Dlg5/Il12rb1	24
GO:0002031	G protein-coupled receptor internalization	BP	0.3	0.000134	0.00122	2.91	0.000828	Calca/Htr1b/Arrb1/Arrb2/Ptger3/Apln	6
GO:0043116	negative regulation of vascular permeability	BP	0.3	0.000134	0.00122	2.91	0.000828	Angpt1/Ddah1/Fermt2/Akap12/Apoe/Cldn5	6
GO:0051258	protein polymerization	BP	0.0942	0.000135	0.00122	2.91	0.000831	Kank4/Map2/Evl/Hcls1/Tmod2/Pfn2/Icam1/Cdh5/Catip/Coro1a/Rp1/Esam/Tubb4a/Daam2/Pecam1/Scin/Nckap1l/Slain1/Nin/Bin1/Arhgap28/Cdc42ep5/Cav1/Cyfip2/Tppp/Map7d3	26
GO:0006940	regulation of smooth muscle contraction	BP	0.159	0.000146	0.00132	2.88	9e-04	Adra1a/Npnt/Abat/Calca/Gucy1a1/Kit/Kcnma1/Ptger3/Calcrl/Atp1a2/Cav1	11
GO:0046513	ceramide biosynthetic process	BP	0.159	0.000146	0.00132	2.88	9e-04	St8sia2/St8sia4/Agk/Sptlc3/Cers4/St6galnac4/St3gal2/St8sia6/Degs2/St6galnac6/Smpd1	11
GO:0042311	vasodilation	BP	0.172	0.000149	0.00134	2.87	0.000915	Kdr/Npr3/Ednrb/Itga1/Calca/Ptprm/Gucy1a1/Apoe/Kcnma1/Bdkrb2	10
GO:0003208	cardiac ventricle morphogenesis	BP	0.148	0.000153	0.00137	2.86	0.000935	Col11a1/Sfrp2/Nog/Foxf1/Mef2c/Lrp2/Cpe/Ccm2l/Heyl/Ednra/Myl3/Heg1	12
GO:0043279	response to alkaloid	BP	0.148	0.000153	0.00137	2.86	0.000935	Slc1a3/Ryr1/Abat/Slc8a1/Drd4/Htr1b/Ednra/Htr2a/Selenon/Dlg4/Gstm7/Smpd1	12
GO:0014909	smooth muscle cell migration	BP	0.132	0.000158	0.00142	2.85	0.000964	Cyp1b1/Mdk/Igf1/Ddr2/Drd4/Tert/Mef2c/Myo5a/Has2/Adamts1/Postn/Nox4/Enpp1/Pcsk5	14
GO:0097106	postsynaptic density organization	BP	0.211	0.000161	0.00144	2.84	0.00098	Ptprd/Nlgn1/Cdh2/Lrrc4b/Nptx1/Shank2/Slitrk3/Syngap1	8
GO:1901385	regulation of voltage-gated calcium channel activity	BP	0.211	0.000161	0.00144	2.84	0.00098	Drd4/Cacna2d1/Stac2/Dysf/Rrad/Gnb5/Cacna1a/Cacnb4	8
GO:0035904	aorta development	BP	0.157	0.000167	0.00149	2.83	0.00101	Tbx2/Kif7/Fkbp10/Lrp2/Plxnd1/Prdm1/Aplnr/Enpp1/Ednra/Prickle1/Efemp2	11
GO:1902107	positive regulation of leukocyte differentiation	BP	0.106	0.000167	0.00149	2.83	0.00101	Ihh/Lef1/Mdk/Cd83/Hcls1/Pik3r6/Gli3/Calca/Prdm1/Cd1d1/Sox12/Zbtb46/Nckap1l/Kitl/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il2rg	20
GO:1903708	positive regulation of hemopoiesis	BP	0.106	0.000167	0.00149	2.83	0.00101	Ihh/Lef1/Mdk/Cd83/Hcls1/Pik3r6/Gli3/Calca/Prdm1/Cd1d1/Sox12/Zbtb46/Nckap1l/Kitl/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il2rg	20
GO:0052547	regulation of peptidase activity	BP	0.0813	0.000168	0.00149	2.83	0.00101	Hgf/Sfrp2/Cd109/Spink1/Igf1/Tfpi/Aph1b/Cd44/Gpc3/Bok/Grin2b/Wdr35/Serpine2/Mical1/Wfdc3/Ift57/Serpini1/Wnt9a/Ppm1f/Hip1/Bin1/Arrb1/Epha7/Rcn3/Asph/Dlc1/Nlrp1b/Arrb2/Ccn2/Fyn/Pi16/Pi15/Mgmt/Simc1/Cav1/Cyfip2	36
GO:2000027	regulation of animal organ morphogenesis	BP	0.12	0.000169	0.0015	2.82	0.00102	Hgf/Sfrp2/Ar/Apcdd1/Wnt11/Hoxd11/Nog/Nkd1/Hoxa11/Gpc3/Znrf3/Tnfrsf11b/Agtr1a/Ednra/Fzd2/Dact1	16
GO:0032944	regulation of mononuclear cell proliferation	BP	0.0964	0.00017	0.0015	2.82	0.00102	Ihh/Igf1/Cd44/Mef2c/Mapk8ip1/Tnfsf13b/Prdm1/Cd1d1/Coro1a/Btla/Itgal/Il27ra/H2-Ab1/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Pde5a/H2-Aa/Stat5b/Zap70/Dlg5/Il12rb1	24
GO:0030308	negative regulation of cell growth	BP	0.103	0.000171	0.00151	2.82	0.00103	Tro/Sfrp2/Map2/Sema5a/Wnt11/Sema5b/Sema7a/Nrp1/Serpine2/Cth/Minar1/Enpp1/Caprin2/Sema3g/Epha7/Fhl1/P3h1/Rrad/Pi16/Sema6a/Tspyl2	21
GO:0003170	heart valve development	BP	0.169	0.000173	0.00152	2.82	0.00103	Stra6/Nos3/Mef2c/Erg/Prdm1/Aplnr/Emilin1/Tie1/Heyl/Dchs1	10
GO:0042552	myelination	BP	0.109	0.000173	0.00152	2.82	0.00103	Ptprz1/Hgf/Igf1/Epb41l3/Mpdz/Cdh2/Wasf3/Myo5a/Id4/Jam3/Slc8a3/Nfasc/Enpp1/Cldn5/Fyn/Abcd2/Ptn/Tppp/Itgb4	19
GO:0008306	associative learning	BP	0.125	0.000175	0.00153	2.82	0.00104	Cacna1c/Nog/Drd4/Grin2b/B4galt2/Pde1b/Adcy3/Shank2/Cacna1e/Kit/Nlgn3/Atp1a2/Brsk1/Syngap1/Ddhd2	15
GO:1903131	mononuclear cell differentiation	BP	0.0788	0.000175	0.00153	2.82	0.00104	Ihh/Lef1/Mdk/Cd83/Itm2a/Cd44/Il11ra1/Mef2c/Itk/Cd3g/Pik3r6/Gli3/Dock2/Flt3/Tnfsf13b/Dock10/Zeb1/Prdm1/Cd1d1/Jag2/Lfng/Loxl3/Kit/H2-Ab1/Cracr2a/Enpp1/Sox12/Zbtb46/Irf8/Nckap1l/Satb1/Hdac9/H2-Aa/Stat5b/Gimap5/Zap70/Mfng/Gimap3/Il2rg	39
GO:0070507	regulation of microtubule cytoskeleton organization	BP	0.112	0.000175	0.00153	2.81	0.00104	Map2/Phldb2/Mpdz/Gnai1/Cdh5/Epha3/Rp1/Map9/Tubb4a/Slain1/Nin/Pkd1/Dysf/Ttbk2/Cep97/Mapre2/Cav1/Tppp	18
GO:0001558	regulation of cell growth	BP	0.0803	0.000176	0.00154	2.81	0.00105	Tro/Sfrp2/Map2/Sema5a/Wnt11/Col14a1/Igf1/Ptch2/Sema5b/Epb41l3/Cpne5/Cd44/Sema7a/Nrp1/Fn1/Serpine2/Cxcl12/Klhl22/Kif26a/Cth/Minar1/Apoe/Cd38/Enpp1/Caprin2/Sema3g/Slc23a2/Epha7/Cacng7/Fhl1/P3h1/Csf2rb/Rrad/Pi16/Sema6a/Tspyl2/Igfbp4	37
GO:0006066	alcohol metabolic process	BP	0.087	0.00018	0.00157	2.8	0.00107	Apob/Cyp1b1/Ttr/Cyp7b1/Hmgcs2/Ednrb/Soat1/Inpp4b/Sptlc3/Plcb1/Pth1r/Plpp3/Dkk3/Tsku/Apoe/Enpp1/Kcnma1/Bpnt1/Adcyap1r1/Degs2/Abca5/Cyp46a1/Dysf/Abcg1/Ipmk/Cacna1h/Sord/Plpp1/Smpd1/Lipe	30
GO:0032411	positive regulation of transporter activity	BP	0.119	0.000185	0.00161	2.79	0.00109	Tcaf1/Drd4/Cacna2d1/Myo5a/Ank2/Plcb1/Trpc6/Nlgn3/Cracr2a/Ednra/Stac2/Asph/Pkd2/Gstm7/Abcb1a/Cacnb4	16
GO:0030509	BMP signaling pathway	BP	0.108	0.000186	0.00161	2.79	0.0011	Sfrp2/Lef1/Kdr/Nog/Rnf165/Fst/Gpc3/Zfp423/Lrp2/Gdf7/Cdh5/Kcp/Smad9/Tnfaip6/Hipk2/Neo1/Fstl1/Cav1/Tmprss6	19
GO:0051494	negative regulation of cytoskeleton organization	BP	0.108	0.000186	0.00161	2.79	0.0011	Kank4/Map2/Evl/Phldb2/Tmod2/Pfn2/Cdh5/Coro1a/Rp1/Tubb4a/Arhgap6/Tmeff2/Pecam1/Scin/Dysf/Arhgap28/Ttbk2/Dlc1/Plekhh2	19
GO:0014910	regulation of smooth muscle cell migration	BP	0.137	0.000187	0.00162	2.79	0.0011	Cyp1b1/Mdk/Igf1/Ddr2/Drd4/Tert/Mef2c/Myo5a/Has2/Adamts1/Postn/Nox4/Pcsk5	13
GO:0048864	stem cell development	BP	0.137	0.000187	0.00162	2.79	0.0011	Sema5a/Sema5b/Zeb2/Sema7a/Nrp1/Cdh2/Ednrb/Fn1/Edn3/Ednra/Sema3g/Kitl/Sema6a	13
GO:0055117	regulation of cardiac muscle contraction	BP	0.155	0.00019	0.00164	2.78	0.00112	Cacna1c/Adra1a/Slc8a1/Stc1/Ank2/Bin1/Pde5a/Cacna1h/Ccn2/Atp1a2/Cav1	11
GO:0043583	ear development	BP	0.0956	0.000191	0.00165	2.78	0.00112	Col11a1/Stra6/Nog/Igf1/Tbx2/Osr2/Tshz1/Lrig3/Gli3/Zeb1/Jag2/Cecr2/Lin7a/Tsku/Enpp1/Kcnma1/Tbx3/Ednra/Osr1/Dchs1/Fzd2/Fat4/Kcnq4/Itga8	24
GO:0090100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.124	0.000192	0.00165	2.78	0.00112	Kdr/Rnf165/Zeb2/Npnt/Gpc3/Gdf11/Zfp423/Gdf7/Cdh5/Gdf10/Cdkn1c/Kcp/Hipk2/Neo1/Itga8	15
GO:0019228	neuronal action potential	BP	0.184	0.000192	0.00165	2.78	0.00113	Kcnd2/P2rx2/Scn1a/Scn2a/Grik2/Kcnma1/Kcnc4/Cacna1h/Scn3a	9
GO:0030324	lung development	BP	0.0975	0.000195	0.00168	2.78	0.00114	Gli1/Stra6/Hhip/Kdr/Nog/Igf1/Pkdcc/Tbx2/Nos3/Gpc3/Foxf1/Hopx/Gli3/Tcf21/Tshz3/Loxl3/Mgp/Ltbp3/Heg1/Rcn3/Selenon/Ccn2/Dlg5	23
GO:0045586	regulation of gamma-delta T cell differentiation	BP	0.357	0.000198	0.00169	2.77	0.00115	Lef1/Nckap1l/Stat5b/Gimap5/Gimap3	5
GO:0046643	regulation of gamma-delta T cell activation	BP	0.357	0.000198	0.00169	2.77	0.00115	Lef1/Nckap1l/Stat5b/Gimap5/Gimap3	5
GO:0051967	negative regulation of synaptic transmission, glutamatergic	BP	0.357	0.000198	0.00169	2.77	0.00115	Grik1/Myo5a/Htr1b/Grik2/Htr2a	5
GO:1905809	negative regulation of synapse organization	BP	0.357	0.000198	0.00169	2.77	0.00115	Arhgef15/Apoe/Epha7/Nfatc4/Ptn	5
GO:0035924	cellular response to vascular endothelial growth factor stimulus	BP	0.167	0.000199	0.0017	2.77	0.00115	Kdr/Nrp1/Ptp4a3/Prkd1/Jcad/Vegfc/Tcf4/Atp2b4/Sema6a/Adgra2	10
GO:0048469	cell maturation	BP	0.0991	0.00021	0.00178	2.75	0.00121	Epha8/Ihh/Pla2g10/Kdr/Spink1/Cspg4/Ednrb/Lrrk2/Gdf11/Flvcr1/Calca/Plcb1/Rps6ka2/Pth1r/Dlg2/Cdkn1c/Nfasc/Kcnma1/Ednra/Lhx6/Tal1/Septin4	22
GO:0002029	desensitization of G protein-coupled receptor signaling pathway	BP	0.233	0.00021	0.00178	2.75	0.00121	Calca/Htr1b/Aplnr/Arrb1/Arrb2/Ptger3/Apln	7
GO:0022401	negative adaptation of signaling pathway	BP	0.233	0.00021	0.00178	2.75	0.00121	Calca/Htr1b/Aplnr/Arrb1/Arrb2/Ptger3/Apln	7
GO:0045932	negative regulation of muscle contraction	BP	0.233	0.00021	0.00178	2.75	0.00121	Calca/Gucy1a1/Kcnma1/Bin1/Pde5a/Calcrl/Atp1a2	7
GO:0008366	axon ensheathment	BP	0.107	0.000215	0.00181	2.74	0.00123	Ptprz1/Hgf/Igf1/Epb41l3/Mpdz/Cdh2/Wasf3/Myo5a/Id4/Jam3/Slc8a3/Nfasc/Enpp1/Cldn5/Fyn/Abcd2/Ptn/Tppp/Itgb4	19
GO:0007517	muscle organ development	BP	0.0849	0.000216	0.00181	2.74	0.00123	Col11a1/Stra6/Angpt1/Lef1/Hoxd10/Ryr1/Nog/P2rx2/Hoxd9/Mef2c/Id3/Tcf21/Lrp2/Ccm2l/Heyl/Ednra/Igf2/Myl3/Hdac9/Heg1/Dysf/Fhl1/Selenon/Fzd2/Hlf/Efemp2/Sgcb/Large1/Cav1/Zfp689/Usp2	31
GO:0002260	lymphocyte homeostasis	BP	0.143	0.000217	0.00182	2.74	0.00124	Cd44/Mef2c/Sh2b2/Tnfsf13b/Dock10/Coro1a/Enpp1/Nckap1l/Stat5b/Gimap5/Gimap3/Lat	12
GO:0006809	nitric oxide biosynthetic process	BP	0.143	0.000217	0.00182	2.74	0.00124	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	12
GO:0007338	single fertilization	BP	0.11	0.000221	0.00185	2.73	0.00126	Ar/Pla2g10/Hoxd10/Hoxd11/Spink1/Hoxa11/Hoxd9/Hoxa10/Adcy3/Plcb1/Trpc6/Glrb/Cecr2/Hoxa9/Cacna1h/Ccdc136/Pkdrej/Stx2	18
GO:0007548	sex differentiation	BP	0.0883	0.000225	0.00188	2.73	0.00128	Tex15/Stra6/Sfrp2/Angpt1/Ar/Kdr/Nos3/Fst/Hoxa11/Hoxa10/Mmp2/Icam1/Adamts1/Tcf21/Lrp2/Lfng/Kit/Tbx3/Hoxa9/Rhobtb3/Kitl/Smad9/Tnfaip6/Arrb1/Osr1/Arrb2/Stat5b/Abcb1a	28
GO:0034332	adherens junction organization	BP	0.18	0.000226	0.00188	2.73	0.00128	Fermt2/Cdh6/Jam3/Cdh10/Cdh5/Abi2/Cdh11/Dchs1/Dlg5	9
GO:1903053	regulation of extracellular matrix organization	BP	0.18	0.000226	0.00188	2.73	0.00128	Sema5a/Ddr2/Prdm5/Phldb2/Ets1/Has2/Emilin1/Tie1/Efemp2	9
GO:0042596	fear response	BP	0.164	0.000229	0.00191	2.72	0.0013	Ankfn1/Mdk/Drd4/Mef2c/Grin2b/Cacna1e/Grik2/Apoe/Gng7/Atp1a2	10
GO:0002718	regulation of cytokine production involved in immune response	BP	0.134	0.000232	0.00192	2.72	0.00131	Angpt1/Sema7a/Tek/Gprc5b/Tril/Kit/Cd226/Lacc1/Xcl1/Gimap5/Gimap3/Cd96/Clnk	13
GO:0070482	response to oxygen levels	BP	0.0894	0.000238	0.00197	2.7	0.00134	Kcnk3/Kcnd2/Ryr1/Kdr/Ddah1/Abat/Slc8a1/Cbs/P2rx2/Pygm/Tert/Mmp2/Gucy1a2/Grin2b/Tek/Slc8a3/Gucy1b1/Gucy1a1/Scn2a/Vegfc/Cd38/Kcnma1/Ednra/Ndnf/Cav1/Cpeb1/Hif3a	27
GO:0050921	positive regulation of chemotaxis	BP	0.113	0.000241	0.002	2.7	0.00136	Sema5a/Mdk/Kdr/Nrp1/Fn1/Prkd1/Cxcr3/Cxcl12/Cdh13/Edn3/Ppm1f/Vegfc/Ednra/Xcl1/Nckap1l/Dysf/Ptn	17
GO:0046637	regulation of alpha-beta T cell differentiation	BP	0.151	0.000245	0.00202	2.69	0.00138	Ihh/Cd83/Gli3/Prdm1/Cd1d1/Loxl3/Nckap1l/Gimap5/Zap70/Gimap3/Il2rg	11
GO:0001945	lymph vessel development	BP	0.226	0.000262	0.00214	2.67	0.00146	Kdr/Vash1/Vegfc/Tie1/Pkd1/Heg1/Svep1	7
GO:0050951	sensory perception of temperature stimulus	BP	0.226	0.000262	0.00214	2.67	0.00146	Ano1/Cxcl12/Calca/Grik2/Enpp1/Htr2a/Arrb2	7
GO:0086010	membrane depolarization during action potential	BP	0.226	0.000262	0.00214	2.67	0.00146	Cacna1c/Scn4b/Scn1a/Cacna2d1/Scn2a/Cacna1h/Scn3a	7
GO:0099633	protein localization to postsynaptic specialization membrane	BP	0.226	0.000262	0.00214	2.67	0.00146	Gpc6/Nptx1/Dlg2/Nptxr/Magi2/Cacng7/Dlg4	7
GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	BP	0.226	0.000262	0.00214	2.67	0.00146	Gpc6/Nptx1/Dlg2/Nptxr/Magi2/Cacng7/Dlg4	7
GO:1904752	regulation of vascular associated smooth muscle cell migration	BP	0.226	0.000262	0.00214	2.67	0.00146	Ddr2/Drd4/Tert/Mef2c/Myo5a/Adamts1/Pcsk5	7
GO:0006584	catecholamine metabolic process	BP	0.161	0.000263	0.00215	2.67	0.00146	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Hdc/Agtr1a/Ednra/Sult1a1	10
GO:0009712	catechol-containing compound metabolic process	BP	0.161	0.000263	0.00215	2.67	0.00146	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Hdc/Agtr1a/Ednra/Sult1a1	10
GO:0031102	neuron projection regeneration	BP	0.161	0.000263	0.00215	2.67	0.00146	Gap43/Hgf/Mmp2/Thy1/Matn2/Enpp1/Rtn4rl1/Neo1/Xylt1/Ptn	10
GO:0086065	cell communication involved in cardiac conduction	BP	0.195	0.000282	0.00229	2.64	0.00156	Cacna1c/Kcnd3/Slc8a1/Scn4b/Cacna2d1/Ank2/Gjc1/Cav1	8
GO:2000463	positive regulation of excitatory postsynaptic potential	BP	0.195	0.000282	0.00229	2.64	0.00156	Nlgn1/Drd4/Stx1b/Grin2b/Tbc1d24/Nlgn3/Dlg4/Cux2	8
GO:0030010	establishment of cell polarity	BP	0.111	0.000282	0.00229	2.64	0.00156	Ankfn1/Map2/Fez1/Foxf1/Jam3/Dock2/Cdh5/Msn/Prickle2/Myo9a/Sh3bp1/Ubxn2b/Frmd4b/Pkd1/Pard3b/Frmd4a/Brsk1	17
GO:0006672	ceramide metabolic process	BP	0.131	0.000284	0.0023	2.64	0.00157	St8sia2/St8sia4/Agk/Sptlc3/Cers4/Plpp3/St6galnac4/St3gal2/St8sia6/Degs2/St6galnac6/Plpp1/Smpd1	13
GO:0008202	steroid metabolic process	BP	0.0858	0.000287	0.00232	2.63	0.00158	Apob/Cyp3a59/Cyp1b1/Cyp3a25/Nr5a2/Cyp7b1/Igf1/Hmgcs2/Ednrb/Chst10/Soat1/Dkk3/Kit/Tsku/Apoe/Enpp1/Agtr1a/Kcnma1/Igf2/Snai1/Ebpl/Abca5/Cyp46a1/Abcg1/Cacna1h/Stat5b/Smpd1/Lipe/Sult1a1	29
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	BP	0.333	0.000287	0.00232	2.63	0.00158	Sfrp2/Nkd1/Gpc3/Znrf3/Dact1	5
GO:0055067	monovalent inorganic cation homeostasis	BP	0.107	0.000298	0.0024	2.62	0.00164	Slc1a3/Car4/Slc12a8/Slc8a1/Ednrb/Lrrk2/Slc9a7/Dmxl2/Agtr1a/Kcnma1/Slc9a5/Ednra/Lacc1/Aqp11/Slc4a3/Slc12a4/Atp1a2/Slc4a8	18
GO:0072678	T cell migration	BP	0.159	0.000301	0.00243	2.62	0.00165	Itga4/Itgb7/Icam1/Cxcr3/Cxcl12/Msn/Itgal/Il27ra/Cd200/Xcl1	10
GO:0035418	protein localization to synapse	BP	0.138	0.000304	0.00244	2.61	0.00166	Gpc6/Nlgn1/Stx1b/Nptx1/Slitrk3/Dlg2/Nlgn3/Nptxr/Magi2/Nsg1/Cacng7/Dlg4	12
GO:0055001	muscle cell development	BP	0.0965	0.000306	0.00246	2.61	0.00167	Sgcd/Col14a1/Ryr1/Igf1/Adra1a/Slc8a1/P2rx2/Tmod2/Mef2c/Ank2/Tbx3/Ednra/Bin1/Hdac9/Dysf/Flnc/Selenon/Nfatc4/Pi16/Efemp2/Sgcb/Cacnb4	22
GO:0032715	negative regulation of interleukin-6 production	BP	0.173	0.000308	0.00246	2.61	0.00168	Hgf/Flt3/Il27ra/Havcr2/Cd200/Nckap1l/Arrb1/Cd84/Arrb2	9
GO:1902622	regulation of neutrophil migration	BP	0.173	0.000308	0.00246	2.61	0.00168	Mdk/Jam3/Ednra/Xcl1/Nckap1l/Tnfaip6/Dysf/Ptger3/Mpp1	9
GO:0045669	positive regulation of osteoblast differentiation	BP	0.147	0.000312	0.00249	2.6	0.0017	Sfrp2/Igf1/Ddr2/Npnt/Fermt2/Mef2c/Prkd1/Gli3/Nell1/Gdf10/Lrp3	11
GO:0015812	gamma-aminobutyric acid transport	BP	0.261	0.000313	0.00249	2.6	0.0017	Grik1/Abat/Htr1b/Gabbr1/Cacna1a/Cacnb4	6
GO:0050961	detection of temperature stimulus involved in sensory perception	BP	0.261	0.000313	0.00249	2.6	0.0017	Ano1/Cxcl12/Calca/Grik2/Htr2a/Arrb2	6
GO:0032092	positive regulation of protein binding	BP	0.13	0.000314	0.0025	2.6	0.0017	Tert/Lrrk2/Plxnd1/Lfng/Apoe/Caprin2/Arrb1/Hipk2/Pkd1/Cldn5/Mfng/Cav1/Dact1	13
GO:0051100	negative regulation of binding	BP	0.107	0.000321	0.00254	2.59	0.00173	Map2/Lef1/Itga4/Nog/Zfp462/Lrrk2/Ccm2l/Twist2/Dysf/Arhgap28/Ttbk2/Nfatc4/Arrb2/Habp4/Nes/Cav1/Dact1/Zfp90	18
GO:0071248	cellular response to metal ion	BP	0.107	0.000321	0.00254	2.59	0.00173	Slc13a5/Nlgn1/Syt13/Cpne5/Fn1/Lrrk2/Nptx1/Mef2c/Rasgrp2/Dlg2/Adcy7/Syt7/Asph/Nfatc4/Pkd2/Slc25a23/Dlg4/Smpd1	18
GO:0010875	positive regulation of cholesterol efflux	BP	0.219	0.000323	0.00256	2.59	0.00174	Pltp/Apoe/Ptch1/Abcg1/Abca8b/Cav1/Nr1h3	7
GO:0023058	adaptation of signaling pathway	BP	0.219	0.000323	0.00256	2.59	0.00174	Calca/Htr1b/Aplnr/Arrb1/Arrb2/Ptger3/Apln	7
GO:0007219	Notch signaling pathway	BP	0.103	0.000329	0.0026	2.58	0.00177	Tbx2/Aph1b/Cdh6/Ptp4a3/Zfp423/Postn/Jag2/Lfng/Kit/Hoxd3/Heyl/Snai1/Arrb1/Dtx3/Tspan5/Fat4/Egfl7/Mfng/Bend6	19
GO:0014046	dopamine secretion	BP	0.19	0.000335	0.00264	2.58	0.0018	Syt13/Abat/Myo5a/Cxcl12/Htr1b/Syt7/Htr2a/Gabbr1	8
GO:0014059	regulation of dopamine secretion	BP	0.19	0.000335	0.00264	2.58	0.0018	Syt13/Abat/Myo5a/Cxcl12/Htr1b/Syt7/Htr2a/Gabbr1	8
GO:0003281	ventricular septum development	BP	0.136	0.000338	0.00266	2.57	0.00181	Stra6/Wnt11/Nog/Nos3/Lrp2/Prdm1/Aplnr/Cplane1/Tbx3/Heyl/Heg1/Fzd2	12
GO:0051250	negative regulation of lymphocyte activation	BP	0.106	0.000345	0.0027	2.57	0.00184	Ihh/Mdk/Cd44/Gli3/Flt3/Prdm1/Loxl3/Btla/H2-Ab1/Havcr2/Nckap1l/Pde5a/Fgr/H2-Aa/Gimap5/Dlg5/Gimap3/Clnk	18
GO:1904064	positive regulation of cation transmembrane transport	BP	0.106	0.000345	0.0027	2.57	0.00184	Cacna1c/Drd4/Cacna2d1/Cxcr3/Edn3/Ank2/Plcb1/Thy1/Nlgn3/Aplnr/Cracr2a/Agtr1a/Ednra/Stac2/Asph/Pkd2/Gstm7/Cacnb4	18
GO:0046638	positive regulation of alpha-beta T cell differentiation	BP	0.17	0.000357	0.00279	2.55	0.0019	Ihh/Cd83/Gli3/Cd1d1/Nckap1l/Gimap5/Zap70/Gimap3/Il2rg	9
GO:0002366	leukocyte activation involved in immune response	BP	0.0856	0.000373	0.00292	2.54	0.00198	Lef1/Mdk/Itm2a/Foxf1/Icam1/Dock2/Eif2ak4/Dock10/Lfng/Loxl3/Coro1a/Kit/Itgal/Il27ra/Cracr2a/Enpp1/Havcr2/Irf8/Nckap1l/Dysf/Myo1f/Cd84/Fgr/Mfng/Lat/Rab27a/Apbb1ip/Clnk	28
GO:0120034	positive regulation of plasma membrane bounded cell projection assembly	BP	0.122	0.000374	0.00292	2.54	0.00198	Nlgn1/Ccdc88a/Nrp1/Abi2/Kit/Rp1/Kctd17/Eps8l1/Crocc/Ttbk2/Dzip1/Palm/Dpysl3/Cdc42ep5	14
GO:0045619	regulation of lymphocyte differentiation	BP	0.0995	0.000379	0.00295	2.53	0.00201	Ihh/Lef1/Mdk/Cd83/Cd44/Pik3r6/Gli3/Flt3/Zeb1/Prdm1/Cd1d1/Loxl3/Sox12/Nckap1l/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il2rg	20
GO:0002687	positive regulation of leukocyte migration	BP	0.108	0.000383	0.00298	2.53	0.00203	Mdk/Itga4/Icam1/Cxcl12/Jam3/Edn3/Thy1/Vegfc/Sele/Ednra/Pecam1/Xcl1/Nckap1l/Kitl/Dysf/Ptger3/Ptn	17
GO:0046632	alpha-beta T cell differentiation	BP	0.116	0.000388	0.00301	2.52	0.00205	Ihh/Lef1/Cd83/Itk/Gli3/Prdm1/Cd1d1/Loxl3/Cracr2a/Nckap1l/Satb1/Gimap5/Zap70/Gimap3/Il2rg	15
GO:0009187	cyclic nucleotide metabolic process	BP	0.212	0.000395	0.00305	2.52	0.00207	Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7/Pde5a/Cacnb4	7
GO:0048566	embryonic digestive tract development	BP	0.212	0.000395	0.00305	2.52	0.00207	Stra6/Ihh/Pkdcc/Foxf1/Gli3/Tcf21/Pcsk5	7
GO:0048841	regulation of axon extension involved in axon guidance	BP	0.212	0.000395	0.00305	2.52	0.00207	Sema5a/Sema5b/Sema7a/Nrp1/Cxcl12/Sema3g/Sema6a	7
GO:0060740	prostate gland epithelium morphogenesis	BP	0.212	0.000395	0.00305	2.52	0.00207	Ar/Nog/Cyp7b1/Igf1/Cd44/Mmp2/Id4	7
GO:0086002	cardiac muscle cell action potential involved in contraction	BP	0.186	0.000397	0.00306	2.51	0.00208	Cacna1c/Kcnd3/Scn4b/Scn1a/Cacna2d1/Ank2/Bin1/Cav1	8
GO:0002693	positive regulation of cellular extravasation	BP	0.25	0.000402	0.00309	2.51	0.0021	Mdk/Icam1/Jam3/Thy1/Pecam1/Ptger3	6
GO:0010842	retina layer formation	BP	0.25	0.000402	0.00309	2.51	0.0021	Sdk2/Arl6/Obsl1/Ptprm/Hipk2/Fat3	6
GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus	BP	0.25	0.000402	0.00309	2.51	0.0021	Ptp4a3/Jcad/Tcf4/Atp2b4/Sema6a/Adgra2	6
GO:0060046	regulation of acrosome reaction	BP	0.312	0.000403	0.00309	2.51	0.0021	Pla2g10/Spink1/Plcb1/Cacna1h/Pkdrej	5
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	BP	0.312	0.000403	0.00309	2.51	0.0021	Plxnb1/Nrp1/Mef2c/Plxnd1/Ednra	5
GO:0001818	negative regulation of cytokine production	BP	0.0878	0.000404	0.00309	2.51	0.0021	Hgf/Acod1/Angpt1/Lef1/Wnt11/Pla2g10/Cd83/Igf1/Fn1/Flt3/Adcy7/Il27ra/Tsku/Havcr2/Cd200/Nckap1l/Hdac9/Twist2/Arrb1/Mapkbp1/Cd84/Arrb2/Abcd2/Gimap5/Gimap3/Cd96	26
GO:0032330	regulation of chondrocyte differentiation	BP	0.167	0.000412	0.00314	2.5	0.00214	Mdk/Hoxd11/Pkdcc/Hoxa11/Gli3/Wnt9a/Adamts7/Ltbp3/Ccn2	9
GO:0007009	plasma membrane organization	BP	0.108	0.000413	0.00315	2.5	0.00214	Ar/Epb41l3/Ank2/Syt7/Tmeff2/Tie1/Bin1/Dysf/Cavin2/Abcd2/Fat4/Smpd1/Atp10a/Cav1/Xkr5/Stx2/Tlcd2	17
GO:0046209	nitric oxide metabolic process	BP	0.133	0.000418	0.00318	2.5	0.00216	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	12
GO:0021761	limbic system development	BP	0.126	0.000421	0.0032	2.5	0.00218	Lef1/Mdk/Zeb2/Nrp1/Dab1/Id4/Gli3/Tsku/Tbx3/Ndnf/Dclk2/Atp1a2/Bbs1	13
GO:0002715	regulation of natural killer cell mediated immunity	BP	0.152	0.000443	0.00336	2.47	0.00229	Pik3r6/Cd226/Havcr2/Igf2/Arrb2/Stat5b/Gimap5/Gimap3/Cd96/Clnk	10
GO:0002720	positive regulation of cytokine production involved in immune response	BP	0.152	0.000443	0.00336	2.47	0.00229	Sema7a/Tek/Gprc5b/Kit/Cd226/Lacc1/Xcl1/Gimap5/Gimap3/Clnk	10
GO:0002263	cell activation involved in immune response	BP	0.0846	0.000453	0.00343	2.46	0.00233	Lef1/Mdk/Itm2a/Foxf1/Icam1/Dock2/Eif2ak4/Dock10/Lfng/Loxl3/Coro1a/Kit/Itgal/Il27ra/Cracr2a/Enpp1/Havcr2/Irf8/Nckap1l/Dysf/Myo1f/Cd84/Fgr/Mfng/Lat/Rab27a/Apbb1ip/Clnk	28
GO:0070167	regulation of biomineral tissue development	BP	0.125	0.000463	0.0035	2.46	0.00238	Wnt6/Pkdcc/Ddr2/Nos3/Slc8a1/Mef2c/Osr2/Nell1/Mgp/Enpp1/Ltbp3/Osr1/Ptn	13
GO:1901021	positive regulation of calcium ion transmembrane transporter activity	BP	0.182	0.000467	0.00352	2.45	0.0024	Cacna2d1/Ank2/Cracr2a/Stac2/Asph/Pkd2/Gstm7/Cacnb4	8
GO:0010863	positive regulation of phospholipase C activity	BP	0.206	0.000479	0.0036	2.44	0.00245	Adra1a/Itk/Arhgap6/Sele/Adcyap1r1/Htr2a/Dlc1	7
GO:0060512	prostate gland morphogenesis	BP	0.206	0.000479	0.0036	2.44	0.00245	Ar/Nog/Cyp7b1/Igf1/Cd44/Mmp2/Id4	7
GO:1901020	negative regulation of calcium ion transmembrane transporter activity	BP	0.206	0.000479	0.0036	2.44	0.00245	Drd4/Dysf/Rrad/Pkd2/Gstm7/Atp1a2/Gnb5	7
GO:0030833	regulation of actin filament polymerization	BP	0.11	0.000492	0.00369	2.43	0.00251	Kank4/Evl/Hcls1/Tmod2/Pfn2/Icam1/Coro1a/Esam/Daam2/Pecam1/Scin/Nckap1l/Bin1/Arhgap28/Cdc42ep5/Cyfip2	16
GO:0060350	endochondral bone morphogenesis	BP	0.149	0.000502	0.00376	2.43	0.00256	Ihh/Mmp16/Hoxd11/Thbs3/Cbs/Hoxa11/Mef2c/Stc1/Col13a1/Enpp1	10
GO:0007620	copulation	BP	0.24	0.00051	0.00381	2.42	0.00259	Ar/Abat/Drd4/Ednrb/Serpine2/Ednra	6
GO:0035988	chondrocyte proliferation	BP	0.24	0.00051	0.00381	2.42	0.00259	Ihh/Mmp16/Lef1/Ddr2/Stc1/Ccn2	6
GO:1903035	negative regulation of response to wounding	BP	0.13	0.000512	0.00382	2.42	0.0026	Mdk/Cd109/Tfpi/Abat/Phldb2/Serpine2/Apoe/Pros1/Rtn4rl1/Neo1/Ptger3/Xylt1	12
GO:2001057	reactive nitrogen species metabolic process	BP	0.13	0.000512	0.00382	2.42	0.0026	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	12
GO:0030100	regulation of endocytosis	BP	0.0928	0.000521	0.00388	2.41	0.00264	Angpt1/Nlgn1/Drd4/Gpc3/Lrrk2/Cdh13/Lrp2/Epha3/Apoe/Sele/Syt7/Magi2/Nckap1l/Hip1/Bin1/Arrb1/Arrb2/Apln/Dlg4/Smpd1/Cav1/Nr1h3	22
GO:0051648	vesicle localization	BP	0.0995	0.000526	0.00391	2.41	0.00266	Syn2/Map2/Itga4/Nlgn1/Sec16b/Cdh2/Lrrk2/Myo5a/Ppfia2/Kif1a/Nlgn3/Lin7a/Magi2/5730455P16Rik/Pcdh17/Myo1f/Cep19/Rab27a/Arfgap3	19
GO:0061041	regulation of wound healing	BP	0.113	0.000538	0.00399	2.4	0.00271	Cd109/Ddr2/Tfpi/Abat/Phldb2/Fermt2/Serpine2/Plpp3/Apoe/Pros1/Ptger3/Clec7a/St3gal4/Cav1/Cldn1	15
GO:0007588	excretion	BP	0.161	0.000544	0.00402	2.4	0.00274	Mdk/Cacna1c/Adra1a/Ednrb/Stc1/Abcg2/Kcnma1/Ptger3/Abcg3	9
GO:0071709	membrane assembly	BP	0.161	0.000544	0.00402	2.4	0.00274	Ptprd/Nlgn1/Cdh2/Nlgn3/Ubxn2b/Magi2/Cav1/Stx2/Tlcd2	9
GO:1903539	protein localization to postsynaptic membrane	BP	0.161	0.000544	0.00402	2.4	0.00274	Gpc6/Stx1b/Nptx1/Dlg2/Nptxr/Magi2/Nsg1/Cacng7/Dlg4	9
GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	BP	0.294	0.000551	0.00406	2.39	0.00276	Plxnb1/Nrp1/Mef2c/Plxnd1/Ednra	5
GO:0006527	arginine catabolic process	BP	0.4	0.000552	0.00406	2.39	0.00276	Ddah1/Nos3/Fah/Atp2b4	4
GO:0060385	axonogenesis involved in innervation	BP	0.4	0.000552	0.00406	2.39	0.00276	Itga4/Nrp1/Nptx1/Ednra	4
GO:1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	BP	0.4	0.000552	0.00406	2.39	0.00276	Ppp1r16b/Aplnr/Jcad/Agtr1a	4
GO:0021953	central nervous system neuron differentiation	BP	0.0966	0.000553	0.00406	2.39	0.00276	Map2/Hoxd10/Dcc/Zeb2/Nrp1/Id4/Gli3/Gdf7/D16Ertd472e/Tsku/Cdh11/Dync2h1/Ndnf/Dclk2/Lhx6/Tal1/Nin/Ptch1/Ptger3/Cacna1a	20
GO:0061337	cardiac conduction	BP	0.147	0.000566	0.00414	2.38	0.00282	Cacna1c/Kcnd3/Slc8a1/Scn4b/Cacna2d1/Ank2/Gjc1/Bin1/Slc4a3/Cav1	10
GO:0010837	regulation of keratinocyte proliferation	BP	0.2	0.000577	0.00422	2.37	0.00287	Mdk/Cd109/Prkd1/Has2/Stxbp4/Klf9/Twist2	7
GO:2000177	regulation of neural precursor cell proliferation	BP	0.117	0.000578	0.00422	2.37	0.00287	Gli1/Ptprz1/Mdk/Nog/Igf1/Cdh2/Smarca1/Lrrk2/Zfp423/Gli3/Lrp2/Vegfc/Nes/Ptn	14
GO:0015711	organic anion transport	BP	0.0822	0.000582	0.00424	2.37	0.00289	Slc1a3/Car4/Grik1/Pla2g10/Slc13a5/Slc2a3/Abat/Drd4/Slc7a2/Grin2b/Abcg2/Slc36a4/Lrp2/Htr1b/Slc6a15/Bdkrb2/Slc23a2/Sfxn5/Slco4c1/Ptger3/Nfkbie/Slc4a3/Slc38a1/Abcc5/Abcg3/Gabbr1/Slc4a8/Cacna1a/Cacnb4	29
GO:0030099	myeloid cell differentiation	BP	0.0774	0.000598	0.00436	2.36	0.00296	Lef1/Pla2g10/Cd109/P4htm/Hcls1/Ets1/Gpc3/Mef2c/Inpp4b/Flvcr1/Lrrc17/Calca/Plcb1/Fli1/Kit/Heph/Cdkn1c/Tnfrsf11b/Enpp1/Gpr171/Scin/Zbtb46/Irf8/Nckap1l/Tal1/Hoxa9/Kitl/Tnfaip6/Twist2/Rassf2/Nrros/Stat5b/Gimap5/Gimap3	34
GO:0003407	neural retina development	BP	0.136	0.000613	0.00445	2.35	0.00303	Ihh/Sdk2/Arl6/Obsl1/Thy1/Ptprm/Rp1/Rorb/Hipk2/Fat3/Ptn	11
GO:0048863	stem cell differentiation	BP	0.0917	0.000618	0.00448	2.35	0.00305	Sema5a/Sema5b/Zeb2/Sema7a/Nrp1/Cdh2/Ednrb/Fn1/Mef2c/Hoxd4/Edn3/Kit/Ednra/Prickle1/Sema3g/Tal1/Kitl/Ltbp3/Osr1/Pus7/Sema6a/Ptn	22
GO:2000116	regulation of cysteine-type endopeptidase activity	BP	0.0917	0.000618	0.00448	2.35	0.00305	Hgf/Sfrp2/Igf1/Cd44/Bok/Grin2b/Wdr35/Mical1/Ift57/Wnt9a/Ppm1f/Hip1/Arrb1/Epha7/Asph/Dlc1/Nlrp1b/Arrb2/Ccn2/Fyn/Mgmt/Cyfip2	22
GO:0006493	protein O-linked glycosylation	BP	0.158	0.000622	0.00448	2.35	0.00305	Gxylt2/Tet1/Tmtc1/Galnt16/Eogt/St8sia6/Galntl6/Poglut2/Large1	9
GO:0032964	collagen biosynthetic process	BP	0.158	0.000622	0.00448	2.35	0.00305	Ihh/P3h3/Ddr2/Fn1/Emilin1/Rcn3/Arrb2/Ccn2/Cygb	9
GO:0061383	trabecula morphogenesis	BP	0.158	0.000622	0.00448	2.35	0.00305	Nog/Plxnb1/Thbs3/Mmp2/Tek/Adamts1/Ccm2l/Enpp1/Heg1	9
GO:0062237	protein localization to postsynapse	BP	0.158	0.000622	0.00448	2.35	0.00305	Gpc6/Stx1b/Nptx1/Dlg2/Nptxr/Magi2/Nsg1/Cacng7/Dlg4	9
GO:0086001	cardiac muscle cell action potential	BP	0.158	0.000622	0.00448	2.35	0.00305	Cacna1c/Kcnd2/Kcnd3/Scn4b/Scn1a/Cacna2d1/Ank2/Bin1/Cav1	9
GO:0051963	regulation of synapse assembly	BP	0.116	0.000629	0.00452	2.34	0.00308	Gpc6/Ptprd/St8sia2/Nlgn1/Lrrc4b/Nptx1/Mef2c/Adgrl1/Slitrk3/Nlgn3/Epha7/Bhlhb9/Cux2/Dlg5	14
GO:1903115	regulation of actin filament-based movement	BP	0.174	0.000638	0.00458	2.34	0.00311	Cacna1c/Stc1/Ank2/Bin1/Cacna1h/Ptger3/Atp1a2/Cav1	8
GO:0001573	ganglioside metabolic process	BP	0.231	0.00064	0.00458	2.34	0.00311	St8sia2/St8sia4/St6galnac4/St3gal2/St8sia6/St6galnac6	6
GO:0042474	middle ear morphogenesis	BP	0.231	0.00064	0.00458	2.34	0.00311	Nog/Osr2/Tshz1/Enpp1/Ednra/Osr1	6
GO:2000050	regulation of non-canonical Wnt signaling pathway	BP	0.231	0.00064	0.00458	2.34	0.00311	Sfrp2/Nkd1/Gpc3/Znrf3/Daam2/Dact1	6
GO:0042102	positive regulation of T cell proliferation	BP	0.12	0.000666	0.00476	2.32	0.00324	Igf1/Tnfsf13b/Cd1d1/Coro1a/Itgal/Il27ra/Havcr2/Igf2/Xcl1/Nckap1l/Stat5b/Zap70/Il12rb1	13
GO:0014706	striated muscle tissue development	BP	0.0862	0.000679	0.00484	2.31	0.0033	Gli1/Col11a1/AW551984/Angpt1/Lef1/Sgcd/Col14a1/Nog/Igf1/Tbx2/Adra1a/Slc8a1/Mef2c/Lrp2/Ccm2l/Nox4/Tbx3/Gjc1/Ednra/Myl3/Hdac9/Heg1/Arrb2/Pi16/Sgcb	25
GO:0070665	positive regulation of leukocyte proliferation	BP	0.103	0.00068	0.00484	2.31	0.0033	Igf1/Mef2c/Tnfsf13b/Cd1d1/Coro1a/Itgal/Il27ra/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Kitl/Csf2rb/Stat5b/Zap70/Il12rb1	17
GO:0060042	retina morphogenesis in camera-type eye	BP	0.134	0.000681	0.00484	2.31	0.0033	Ihh/Sdk2/Arl6/Obsl1/Thy1/Ptprm/Rp1/Rorb/Hipk2/Fat3/Ptn	11
GO:1901879	regulation of protein depolymerization	BP	0.126	0.000687	0.00488	2.31	0.00332	Map2/Sema5a/Evl/Tmod2/Rp1/Sh3bp1/Scin/Dysf/Asph/Ttbk2/Nes/Plekhh2	12
GO:0048169	regulation of long-term neuronal synaptic plasticity	BP	0.194	0.000691	0.0049	2.31	0.00334	Grik1/Kdr/Grin2b/Kit/Grik2/Dlg4/Syngap1	7
GO:0051251	positive regulation of lymphocyte activation	BP	0.0767	0.000701	0.00497	2.3	0.00338	Ihh/Efnb3/Lef1/Mdk/Cd83/Igf1/Mef2c/Pik3r6/Gli3/Tnfsf13b/Thy1/Prdm1/Cd1d1/Coro1a/Itgal/Il27ra/H2-Ab1/Cd38/Havcr2/Sox12/H2-Ob/Igf2/Xcl1/Nckap1l/H2-Eb1/Clec7a/H2-Aa/Stat5b/Gimap5/Zap70/Gimap3/Il12rb1/Cav1/Il2rg	34
GO:0015872	dopamine transport	BP	0.155	0.000709	0.00502	2.3	0.00342	Slc6a2/Syt13/Abat/Myo5a/Cxcl12/Htr1b/Syt7/Htr2a/Gabbr1	9
GO:0048662	negative regulation of smooth muscle cell proliferation	BP	0.143	0.000715	0.00506	2.3	0.00344	Vipr2/Nos3/Drd4/Npr3/Mef2c/Rgs5/Apoe/Apln/Efemp2/Cav1	10
GO:0071901	negative regulation of protein serine/threonine kinase activity	BP	0.119	0.000728	0.00514	2.29	0.0035	Sfrp2/Slc8a1/Mapk8ip1/Slc8a3/Pkia/Cdkn1c/Apoe/Rasip1/Pkib/Heg1/Lats2/Smpd1/Cav1	13
GO:0007614	short-term memory	BP	0.278	0.000737	0.0052	2.28	0.00353	Mdk/Aph1b/Drd4/Pde5a/Cux2	5
GO:0043114	regulation of vascular permeability	BP	0.17	0.000741	0.00522	2.28	0.00355	Angpt1/Ddah1/Fermt2/Ptp4a3/Akap12/Cdh5/Apoe/Cldn5	8
GO:0030595	leukocyte chemotaxis	BP	0.0921	0.000764	0.00537	2.27	0.00365	Cxcl15/Mdk/Cyp7b1/Ptpro/Ednrb/Cxcr3/Cxcl12/Jam3/Edn3/Itga1/Calca/Coro1a/Kit/Vegfc/Ednra/Xcl1/Nckap1l/Tnfaip6/Dysf/Mpp1/Ptn	21
GO:0046660	female sex differentiation	BP	0.105	0.000766	0.00538	2.27	0.00366	Stra6/Angpt1/Kdr/Nos3/Fst/Mmp2/Adamts1/Lrp2/Lfng/Kit/Tbx3/Kitl/Tnfaip6/Arrb1/Arrb2/Stat5b	16
GO:0014829	vascular associated smooth muscle contraction	BP	0.222	0.000793	0.00553	2.26	0.00376	Slc8a1/Ednrb/Edn3/Cd38/Ednra/Htr2a	6
GO:0016048	detection of temperature stimulus	BP	0.222	0.000793	0.00553	2.26	0.00376	Ano1/Cxcl12/Calca/Grik2/Htr2a/Arrb2	6
GO:0034368	protein-lipid complex remodeling	BP	0.222	0.000793	0.00553	2.26	0.00376	Apob/Pla2g10/Pltp/Apoe/Abca5/Abcg1	6
GO:0034369	plasma lipoprotein particle remodeling	BP	0.222	0.000793	0.00553	2.26	0.00376	Apob/Pla2g10/Pltp/Apoe/Abca5/Abcg1	6
GO:0048843	negative regulation of axon extension involved in axon guidance	BP	0.222	0.000793	0.00553	2.26	0.00376	Sema5a/Sema5b/Sema7a/Nrp1/Sema3g/Sema6a	6
GO:0060004	reflex	BP	0.222	0.000793	0.00553	2.26	0.00376	Adra1a/Npnt/Glrb/Kcnma1/Satb1/Cacna1a	6
GO:0050432	catecholamine secretion	BP	0.141	0.000802	0.00558	2.25	0.00379	Syt13/Abat/Myo5a/Cxcl12/Htr1b/Cadps/Syt7/Htr2a/Ptger3/Gabbr1	10
GO:0043254	regulation of protein-containing complex assembly	BP	0.0769	0.000802	0.00558	2.25	0.00379	Kank4/Map2/Evl/Hcls1/Stx1b/Fermt2/Tmod2/Pfn2/Icam1/Jam3/Cdh5/Msn/Coro1a/Esam/Tubb4a/Apoe/Prrt2/Rasip1/Daam2/Pecam1/Scin/Pcsk5/Nckap1l/Slain1/Tal1/Nin/Bin1/Arhgap28/Cdc42ep5/Cav1/Dact1/Cyfip2/Tppp	33
GO:1903350	response to dopamine	BP	0.153	0.000806	0.00559	2.25	0.0038	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Palm/Gnb5	9
GO:1903351	cellular response to dopamine	BP	0.153	0.000806	0.00559	2.25	0.0038	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Palm/Gnb5	9
GO:0048846	axon extension involved in axon guidance	BP	0.189	0.000821	0.00565	2.25	0.00384	Sema5a/Sema5b/Sema7a/Nrp1/Cxcl12/Sema3g/Sema6a	7
GO:0050901	leukocyte tethering or rolling	BP	0.189	0.000821	0.00565	2.25	0.00384	Itga4/Chst2/Itgb7/Podxl2/Cxcl12/Sele/St3gal4	7
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	BP	0.189	0.000821	0.00565	2.25	0.00384	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Fzd2/Dact1	7
GO:0086091	regulation of heart rate by cardiac conduction	BP	0.189	0.000821	0.00565	2.25	0.00384	Cacna1c/Kcnd3/Scn4b/Cacna2d1/Ank2/Bin1/Cav1	7
GO:1902284	neuron projection extension involved in neuron projection guidance	BP	0.189	0.000821	0.00565	2.25	0.00384	Sema5a/Sema5b/Sema7a/Nrp1/Cxcl12/Sema3g/Sema6a	7
GO:0002028	regulation of sodium ion transport	BP	0.124	0.000829	0.0057	2.24	0.00387	Hecw2/Nos3/Slc8a1/Scn4b/Drd4/Fxyd5/Serpine2/Plcb1/Osr1/Atp2b4/Akt3/Atp1a2	12
GO:0060191	regulation of lipase activity	BP	0.131	0.000836	0.0057	2.24	0.00388	Adra1a/Itk/Arhgap6/Sele/Agtr1a/Adcyap1r1/Htr2a/Hdac9/Dlc1/Angptl4/Nr1h3	11
GO:0072089	stem cell proliferation	BP	0.131	0.000836	0.0057	2.24	0.00388	Sfrp2/Fermt2/Tert/Znrf3/Vegfc/Tbx3/Kitl/Ltbp3/Septin4/Abcb1a/Nes	11
GO:0002399	MHC class II protein complex assembly	BP	0.364	0.000839	0.0057	2.24	0.00388	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0002503	peptide antigen assembly with MHC class II protein complex	BP	0.364	0.000839	0.0057	2.24	0.00388	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0035336	long-chain fatty-acyl-CoA metabolic process	BP	0.364	0.000839	0.0057	2.24	0.00388	Acsl6/Them5/Acot7/Acsl1	4
GO:0061299	retina vasculature morphogenesis in camera-type eye	BP	0.364	0.000839	0.0057	2.24	0.00388	Ndp/Cyp1b1/Nrp1/Arhgef15	4
GO:0071415	cellular response to purine-containing compound	BP	0.364	0.000839	0.0057	2.24	0.00388	Ryr1/Slc8a1/Selenon/Gstm7	4
GO:0097104	postsynaptic membrane assembly	BP	0.364	0.000839	0.0057	2.24	0.00388	Nlgn1/Cdh2/Nlgn3/Magi2	4
GO:0030177	positive regulation of Wnt signaling pathway	BP	0.108	0.000854	0.00579	2.24	0.00394	Sfrp2/Sema5a/Lef1/Zeb2/Nkd1/Tert/Gpc3/Lrrk2/Gprc5b/Peg12/Caprin2/Daam2/Adgra2/Cav1/Dact1	15
GO:0001941	postsynaptic membrane organization	BP	0.167	0.000856	0.00579	2.24	0.00394	Nlgn1/Cdh2/Glrb/Nlgn3/Apoe/Magi2/Dlg4/Ptn	8
GO:0003179	heart valve morphogenesis	BP	0.167	0.000856	0.00579	2.24	0.00394	Stra6/Nos3/Mef2c/Erg/Emilin1/Tie1/Heyl/Dchs1	8
GO:0035137	hindlimb morphogenesis	BP	0.167	0.000856	0.00579	2.24	0.00394	Hoxd10/Aff3/Gpc3/Hoxd9/Osr2/Tbx3/Ptch1/Osr1	8
GO:0042073	intraciliary transport	BP	0.167	0.000856	0.00579	2.24	0.00394	Tub/Wdr35/Ift57/Dync2h1/Arl3/Ttc26/Dync2li1/Bbs1	8
GO:0010876	lipid localization	BP	0.0757	0.000885	0.00597	2.22	0.00406	Apob/Stra6/Nme4/Acsl6/Pla2g10/Acacb/Drd4/Vstm2a/Mest/Soat1/Abcg2/Rbp7/Osbp2/Pltp/Selenom/Apoe/Enpp1/Agtr1a/Syt7/Bdkrb2/Abca5/Dysf/Abcg1/Abca8b/Abcd2/Stat5b/Abcb1a/Atp10a/Acsl1/Osbpl1a/Cav1/Xkr5/Nr1h3/Prelid3a	34
GO:0030041	actin filament polymerization	BP	0.101	0.000891	0.00601	2.22	0.00409	Kank4/Evl/Hcls1/Tmod2/Pfn2/Icam1/Catip/Coro1a/Esam/Daam2/Pecam1/Scin/Nckap1l/Bin1/Arhgap28/Cdc42ep5/Cyfip2	17
GO:0061035	regulation of cartilage development	BP	0.139	0.000896	0.00602	2.22	0.00409	Mdk/Hoxd11/Nog/Pkdcc/Hoxa11/Gli3/Wnt9a/Adamts7/Ltbp3/Ccn2	10
GO:0071868	cellular response to monoamine stimulus	BP	0.139	0.000896	0.00602	2.22	0.00409	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Atp2b4/Palm/Gnb5	10
GO:0071870	cellular response to catecholamine stimulus	BP	0.139	0.000896	0.00602	2.22	0.00409	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Atp2b4/Palm/Gnb5	10
GO:0032091	negative regulation of protein binding	BP	0.122	0.000909	0.00608	2.22	0.00414	Map2/Itga4/Nog/Lrrk2/Ccm2l/Dysf/Ttbk2/Nfatc4/Arrb2/Nes/Cav1/Dact1	12
GO:0042632	cholesterol homeostasis	BP	0.122	0.000909	0.00608	2.22	0.00414	Apob/Pla2g10/Nr5a2/Cyp7b1/Soat1/Tsku/Apoe/Hdac9/Abca5/Abcg1/Cav1/Nr1h3	12
GO:1904063	negative regulation of cation transmembrane transport	BP	0.122	0.000909	0.00608	2.22	0.00414	Hecw2/Drd4/Bin1/Dysf/Osr1/Rrad/Ptger3/Pkd2/Gstm7/Atp1a2/Gnb5/Cav1	12
GO:0097479	synaptic vesicle localization	BP	0.15	0.000913	0.0061	2.21	0.00415	Syn2/Map2/Nlgn1/Cdh2/Lrrk2/Nlgn3/Lin7a/Magi2/Pcdh17	9
GO:0034763	negative regulation of transmembrane transport	BP	0.107	0.00092	0.00614	2.21	0.00418	Hecw2/Drd4/Sh2b2/Enpp1/Bin1/Dysf/Osr1/Rrad/Ptger3/Pkd2/Gstm7/Atp1a2/Gnb5/Cav1/Pid1	15
GO:1905475	regulation of protein localization to membrane	BP	0.095	0.000921	0.00614	2.21	0.00418	Gpc6/Ar/Pkdcc/Tcaf1/Cdh2/Gpc3/Abi3/Myo5a/Epha3/Magi2/Tnfaip6/Stac2/Fyn/Dlg4/Atp2b4/Ptn/Gpc2/Pid1/Nkd2	19
GO:0030500	regulation of bone mineralization	BP	0.129	0.000924	0.00615	2.21	0.00418	Pkdcc/Ddr2/Slc8a1/Mef2c/Osr2/Nell1/Mgp/Enpp1/Ltbp3/Osr1/Ptn	11
GO:0046530	photoreceptor cell differentiation	BP	0.129	0.000924	0.00615	2.21	0.00418	Ihh/Sdk2/Thy1/Prdm1/Rp1/Rorb/Arl3/Ttc26/Nphp1/Ptn/Bbs1	11
GO:0016331	morphogenesis of embryonic epithelium	BP	0.0973	0.000943	0.00626	2.2	0.00426	Sfrp2/Wnt6/Ar/Nog/Zeb2/Lrp2/Gdf7/Ift57/Jag2/Cecr2/Vegfc/Prickle1/Ptch1/Ipmk/Osr1/Dlc1/Fzd2/Rab23	18
GO:0007565	female pregnancy	BP	0.1	0.000952	0.00632	2.2	0.0043	Acod1/Ar/Cbs/Il11ra1/Mmp2/Abcg2/Calca/Syde1/Prdm1/Maged2/Havcr2/Pcsk5/Klf9/Stat5b/Ptn/Stx2/Itgb4	17
GO:0086004	regulation of cardiac muscle cell contraction	BP	0.184	0.00097	0.00641	2.19	0.00436	Cacna1c/Stc1/Ank2/Bin1/Cacna1h/Atp1a2/Cav1	7
GO:1900274	regulation of phospholipase C activity	BP	0.184	0.00097	0.00641	2.19	0.00436	Adra1a/Itk/Arhgap6/Sele/Adcyap1r1/Htr2a/Dlc1	7
GO:0018126	protein hydroxylation	BP	0.214	0.000974	0.00641	2.19	0.00436	P3h3/P4htm/Fkbp10/Asph/P3h1/Crtap	6
GO:0045061	thymic T cell selection	BP	0.214	0.000974	0.00641	2.19	0.00436	Cd3g/Gli3/Dock2/Cd1d1/Jag2/Zap70	6
GO:0061437	renal system vasculature development	BP	0.214	0.000974	0.00641	2.19	0.00436	Angpt1/Nrp1/Tek/Tcf21/Ednra/Osr1	6
GO:0061440	kidney vasculature development	BP	0.214	0.000974	0.00641	2.19	0.00436	Angpt1/Nrp1/Tek/Tcf21/Ednra/Osr1	6
GO:0055092	sterol homeostasis	BP	0.121	0.000995	0.00654	2.18	0.00445	Apob/Pla2g10/Nr5a2/Cyp7b1/Soat1/Tsku/Apoe/Hdac9/Abca5/Abcg1/Cav1/Nr1h3	12
GO:0008542	visual learning	BP	0.137	0.000999	0.00656	2.18	0.00446	Cacna1c/Nog/B4galt2/Pde1b/Cacna1e/Kit/Nlgn3/Atp1a2/Syngap1/Ddhd2	10
GO:0048678	response to axon injury	BP	0.137	0.000999	0.00656	2.18	0.00446	Gap43/Mmp2/Matn2/Enpp1/Rtn4rl1/Sarm1/Neo1/Xylt1/Dpysl3/Ptn	10
GO:0060324	face development	BP	0.148	0.00103	0.00676	2.17	0.0046	Stra6/Lef1/Itga4/Nog/Crispld1/Mmp2/Ednra/Twist2/Asph	9
GO:0030856	regulation of epithelial cell differentiation	BP	0.102	0.00108	0.0071	2.15	0.00483	Cd109/Macroh2a2/Ptch2/Zeb2/Plcb1/Cdh5/Zeb1/Cdkn1c/Tbx3/Spred3/Ptch1/Osr1/Cldn5/Stat5b/Fat4/Cav1	16
GO:0071867	response to monoamine	BP	0.135	0.00111	0.00726	2.14	0.00494	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Atp2b4/Palm/Gnb5	10
GO:0071869	response to catecholamine	BP	0.135	0.00111	0.00726	2.14	0.00494	Nsg2/Drd4/Lrrk2/Htr1b/Htr2a/Nsg1/Gnaz/Atp2b4/Palm/Gnb5	10
GO:0050727	regulation of inflammatory response	BP	0.0798	0.00112	0.00732	2.14	0.00498	Hgf/Acod1/Mdk/Pla2g10/Igf1/Cd44/Sema7a/Ets1/Ednrb/Lrrk2/Foxf1/Slc7a2/Fndc4/Gprc5b/Cdh5/Bcl6b/Apoe/Cd200/Ednra/Lacc1/Xcl1/Tnfaip6/Pde5a/Nlrp1b/Ptger3/Calcrl/Stat5b/Nr1h3	28
GO:0042267	natural killer cell mediated cytotoxicity	BP	0.126	0.00112	0.00732	2.14	0.00498	Pik3r6/Coro1a/Cd226/Havcr2/Igf2/Arrb2/Stat5b/Gzmb/Gimap5/Gimap3/Rab27a	11
GO:0031281	positive regulation of cyclase activity	BP	0.179	0.00114	0.00739	2.13	0.00502	Cacna1c/Vipr2/Nos3/Adcy3/Calca/Adcy4/Adcy7	7
GO:0051180	vitamin transport	BP	0.179	0.00114	0.00739	2.13	0.00502	Stra6/Slc2a3/Abcg2/Lrp2/Slc23a2/Abcc5/Abcg3	7
GO:1904645	response to amyloid-beta	BP	0.179	0.00114	0.00739	2.13	0.00502	Itga4/Igf1/Cacna2d1/Mmp2/Icam1/Fyn/Cacna1a	7
GO:0050680	negative regulation of epithelial cell proliferation	BP	0.0983	0.00116	0.00748	2.13	0.00509	Sfrp2/Ar/Cd109/Gkn3/Gpc3/Mef2c/Cxcr3/Vash1/Ift57/Ptprm/Cdkn1c/Apoe/Klf9/Ptch1/Aqp11/Ptn/Cav1	17
GO:0051058	negative regulation of small GTPase mediated signal transduction	BP	0.145	0.00116	0.00751	2.12	0.00511	Adra1a/Rasa3/Arhgap25/Sh3bp1/Rasip1/Arap3/Heg1/Dlc1/Syngap1	9
GO:0048639	positive regulation of developmental growth	BP	0.0909	0.00118	0.00763	2.12	0.00519	Gli1/Sema5a/Igf1/Tbx2/Cpne5/Acacb/Sema7a/Nrp1/Fn1/Mef2c/Cxcl12/Hopx/Plcb1/Flt3/Apoe/Igf2/Slc23a2/Foxs1/Cacng7/Stat5b	20
GO:0034367	protein-containing complex remodeling	BP	0.207	0.00118	0.00763	2.12	0.00519	Apob/Pla2g10/Pltp/Apoe/Abca5/Abcg1	6
GO:1900027	regulation of ruffle assembly	BP	0.207	0.00118	0.00763	2.12	0.00519	Evl/Nlgn1/Pfn2/Icam1/Eps8l1/Cav1	6
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	BP	0.119	0.00119	0.00764	2.12	0.0052	Adra1a/Npr3/Ednrb/Ano1/Lpar4/Calca/Pth1r/Agtr1a/Ednra/Htr2a/Plcb2/Ptger3	12
GO:0002367	cytokine production involved in immune response	BP	0.113	0.0012	0.00774	2.11	0.00527	Angpt1/Sema7a/Tek/Gprc5b/Tril/Kit/Cd226/Lacc1/Xcl1/Gimap5/Gimap3/Cd96/Clnk	13
GO:0042135	neurotransmitter catabolic process	BP	0.333	0.00122	0.00778	2.11	0.00529	Maob/Abat/Maoa/Naalad2	4
GO:0060073	micturition	BP	0.333	0.00122	0.00778	2.11	0.00529	Cacna1c/Adra1a/Kcnma1/Ptger3	4
GO:0070444	oligodendrocyte progenitor proliferation	BP	0.333	0.00122	0.00778	2.11	0.00529	Ptprz1/Nog/Cdh2/Lrp2	4
GO:0070445	regulation of oligodendrocyte progenitor proliferation	BP	0.333	0.00122	0.00778	2.11	0.00529	Ptprz1/Nog/Cdh2/Lrp2	4
GO:0050728	negative regulation of inflammatory response	BP	0.104	0.00123	0.00784	2.11	0.00534	Hgf/Acod1/Mdk/Pla2g10/Igf1/Cd44/Ets1/Foxf1/Fndc4/Cdh5/Apoe/Cd200/Tnfaip6/Calcrl/Nr1h3	15
GO:0051937	catecholamine transport	BP	0.125	0.00124	0.00786	2.1	0.00535	Slc6a2/Syt13/Abat/Myo5a/Cxcl12/Htr1b/Cadps/Syt7/Htr2a/Ptger3/Gabbr1	11
GO:0032103	positive regulation of response to external stimulus	BP	0.0742	0.00124	0.00786	2.1	0.00535	Acod1/Sema5a/Mdk/Kdr/Nrp1/Ets1/Fn1/Lrrk2/Mmp2/Prkd1/Cxcr3/Cxcl12/Cdh13/Edn3/Gprc5b/Rab34/Cd226/Ppm1f/Vegfc/Havcr2/Emilin1/Ednra/Xcl1/Masp1/Nckap1l/Dysf/Pde5a/Nlrp1b/Ptger3/Stat5b/Gimap5/Gimap3/Ptn/Clnk	34
GO:0045019	negative regulation of nitric oxide biosynthetic process	BP	0.25	0.00124	0.00786	2.1	0.00535	Wdr35/Atp2b4/Gimap5/Gimap3/Cav1	5
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	BP	0.25	0.00124	0.00786	2.1	0.00535	Ano1/Cxcl12/Calca/Htr2a/Arrb2	5
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	BP	0.25	0.00124	0.00786	2.1	0.00535	Scn1a/Grin2b/Cxcl12/Htr2a/Fyn	5
GO:1903236	regulation of leukocyte tethering or rolling	BP	0.25	0.00124	0.00786	2.1	0.00535	Itga4/Chst2/Cxcl12/Sele/St3gal4	5
GO:1904406	negative regulation of nitric oxide metabolic process	BP	0.25	0.00124	0.00786	2.1	0.00535	Wdr35/Atp2b4/Gimap5/Gimap3/Cav1	5
GO:1904754	positive regulation of vascular associated smooth muscle cell migration	BP	0.25	0.00124	0.00786	2.1	0.00535	Ddr2/Tert/Myo5a/Adamts1/Pcsk5	5
GO:0048738	cardiac muscle tissue development	BP	0.0852	0.00128	0.00807	2.09	0.00549	Gli1/Col11a1/AW551984/Angpt1/Sgcd/Col14a1/Nog/Igf1/Tbx2/Adra1a/Slc8a1/Mef2c/Lrp2/Ccm2l/Nox4/Tbx3/Gjc1/Ednra/Myl3/Heg1/Arrb2/Pi16/Sgcb	23
GO:1990266	neutrophil migration	BP	0.108	0.00128	0.00807	2.09	0.00549	Cxcl15/Mdk/Jam3/Edn3/Itga1/Ednra/Pecam1/Xcl1/Nckap1l/Tnfaip6/Dysf/Irak4/Ptger3/Mpp1	14
GO:0008038	neuron recognition	BP	0.157	0.00129	0.00814	2.09	0.00553	Gap43/Prtg/Ptprz1/Efnb3/Sema5a/Nrp1/Ndn/Epha3	8
GO:0010518	positive regulation of phospholipase activity	BP	0.157	0.00129	0.00814	2.09	0.00553	Adra1a/Itk/Arhgap6/Sele/Agtr1a/Adcyap1r1/Htr2a/Dlc1	8
GO:0009064	glutamine family amino acid metabolic process	BP	0.143	0.0013	0.0082	2.09	0.00558	Ddah1/Nos3/Asrgl1/Fah/Amdhd1/Phgdh/Atp2b4/Asl/Slc7a7	9
GO:0044091	membrane biogenesis	BP	0.143	0.0013	0.0082	2.09	0.00558	Ptprd/Nlgn1/Cdh2/Nlgn3/Ubxn2b/Magi2/Cav1/Stx2/Tlcd2	9
GO:0045637	regulation of myeloid cell differentiation	BP	0.0901	0.00132	0.00827	2.08	0.00563	Lef1/P4htm/Hcls1/Ets1/Mef2c/Inpp4b/Lrrc17/Calca/Tnfrsf11b/Gpr171/Scin/Zbtb46/Nckap1l/Tal1/Hoxa9/Kitl/Tnfaip6/Twist2/Rassf2/Stat5b	20
GO:1903828	negative regulation of protein localization	BP	0.0901	0.00132	0.00827	2.08	0.00563	Angpt1/Pkdcc/Drd4/Lrrk2/Abi3/Pkia/Ppm1f/Apoe/Ubxn2b/Cd200/Dclk2/Nin/Ttbk2/Neo1/Ptger3/Frmd4a/Rab23/Lats2/Nr1h3/Pid1	20
GO:0001782	B cell homeostasis	BP	0.175	0.00133	0.00832	2.08	0.00566	Cd44/Mef2c/Sh2b2/Tnfsf13b/Dock10/Enpp1/Nckap1l	7
GO:0051349	positive regulation of lyase activity	BP	0.175	0.00133	0.00832	2.08	0.00566	Cacna1c/Vipr2/Nos3/Adcy3/Calca/Adcy4/Adcy7	7
GO:0060325	face morphogenesis	BP	0.175	0.00133	0.00832	2.08	0.00566	Stra6/Lef1/Nog/Crispld1/Mmp2/Twist2/Asph	7
GO:0009416	response to light stimulus	BP	0.081	0.00133	0.00833	2.08	0.00566	Slc1a3/Sema5a/Cacna1c/Nog/Sema5b/Slc24a4/Mmp2/B4galt2/Pde1b/Cacna1e/Eif2ak4/Fbxl21/Mme/Kit/Rp1/Nlgn3/Arrb1/Nfatc4/Atp1a2/Gnb5/Brsk1/Syngap1/Smpd1/Ddhd2/Usp2/Cacnb4	26
GO:0015850	organic hydroxy compound transport	BP	0.0863	0.00137	0.00853	2.07	0.00581	Apob/Stra6/Maob/Slc6a2/Syt13/Abat/Myo5a/Cxcl12/Slc2a13/Htr1b/Cadps/Selenom/Apoe/Agtr1a/Syt7/Htr2a/Abca5/Abcg1/Abca8b/Ptger3/Gabbr1/Nr1h3	22
GO:0010639	negative regulation of organelle organization	BP	0.0777	0.00137	0.00854	2.07	0.00581	Kank4/Hgf/Map2/Fez1/Igf1/Evl/Phldb2/Tmod2/Bok/Lrrk2/Pfn2/Klhl22/Rps6ka2/Cdh5/Coro1a/Rp1/Tubb4a/Arhgap6/Prrt2/Tmeff2/Pecam1/Scin/Dysf/Arhgap28/Ttbk2/Dlc1/Arrb2/Cep97/Plekhh2	29
GO:0055088	lipid homeostasis	BP	0.0966	0.0014	0.00868	2.06	0.0059	Apob/Pla2g10/Nr5a2/Cyp7b1/Soat1/Tsku/Apoe/Hdac9/Abca5/Rcn3/Zbtb20/Abcg1/Angptl4/Abhd8/Cav1/Tlcd2/Nr1h3	17
GO:0001704	formation of primary germ layer	BP	0.117	0.00141	0.00876	2.06	0.00596	Sfrp2/Lef1/Wnt11/Nog/Hoxa11/Fn1/Foxf1/Snai1/Tal1/Col5a2/Ets2/Kif16b	12
GO:0001892	embryonic placenta development	BP	0.111	0.00141	0.00876	2.06	0.00596	Lef1/Itga4/Slc8a1/Vash1/Syde1/Prdm1/Pcdh12/Cdkn1c/Igf2/Snai1/Pkd1/Pkd2/Vash2	13
GO:0006688	glycosphingolipid biosynthetic process	BP	0.2	0.00143	0.00882	2.05	0.006	St8sia2/St8sia4/St6galnac4/St3gal2/St8sia6/St6galnac6	6
GO:0045724	positive regulation of cilium assembly	BP	0.2	0.00143	0.00882	2.05	0.006	Ccdc88a/Rp1/Kctd17/Crocc/Ttbk2/Dzip1	6
GO:0048745	smooth muscle tissue development	BP	0.2	0.00143	0.00882	2.05	0.006	Stra6/Ihh/Tshz3/Osr1/Efemp2/Itga8	6
GO:0071312	cellular response to alkaloid	BP	0.2	0.00143	0.00882	2.05	0.006	Slc1a3/Ryr1/Slc8a1/Htr1b/Selenon/Gstm7	6
GO:0008347	glial cell migration	BP	0.141	0.00146	0.009	2.05	0.00612	Ptprz1/Apcdd1/Cspg4/Fn1/Dab1/Gli3/Ndn/Matn2/Enpp1	9
GO:0050435	amyloid-beta metabolic process	BP	0.141	0.00146	0.009	2.05	0.00612	Igf1/Aph1b/Rtn1/Slc2a13/Mme/Apoe/Bin1/Abcg1/Mgat3	9
GO:0060193	positive regulation of lipase activity	BP	0.141	0.00146	0.009	2.05	0.00612	Adra1a/Itk/Arhgap6/Sele/Agtr1a/Adcyap1r1/Htr2a/Dlc1/Nr1h3	9
GO:0050798	activated T cell proliferation	BP	0.154	0.00147	0.00904	2.04	0.00615	Igf1/Itgal/Il27ra/Igf2/Satb1/Fyn/Stat5b/Il12rb1	8
GO:0050671	positive regulation of lymphocyte proliferation	BP	0.102	0.00151	0.00927	2.03	0.00631	Igf1/Mef2c/Tnfsf13b/Cd1d1/Coro1a/Itgal/Il27ra/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Stat5b/Zap70/Il12rb1	15
GO:1903038	negative regulation of leukocyte cell-cell adhesion	BP	0.102	0.00151	0.00927	2.03	0.00631	Ihh/Mdk/Cd44/Cxcl12/Gli3/Loxl3/Btla/H2-Ab1/Havcr2/Nckap1l/Pde5a/H2-Aa/Gimap5/Dlg5/Gimap3	15
GO:0008585	female gonad development	BP	0.11	0.00153	0.00934	2.03	0.00636	Angpt1/Kdr/Nos3/Fst/Mmp2/Adamts1/Lfng/Kit/Kitl/Tnfaip6/Arrb1/Arrb2/Stat5b	13
GO:0090288	negative regulation of cellular response to growth factor stimulus	BP	0.115	0.00153	0.00938	2.03	0.00638	Sfrp2/Nog/Lrp2/Emilin1/Tnfaip6/Hipk2/Apln/Atp2b4/Sema6a/Adgra2/Cav1/Tmprss6	12
GO:0030513	positive regulation of BMP signaling pathway	BP	0.171	0.00155	0.00943	2.03	0.00641	Kdr/Rnf165/Gpc3/Zfp423/Cdh5/Kcp/Neo1	7
GO:0051968	positive regulation of synaptic transmission, glutamatergic	BP	0.171	0.00155	0.00943	2.03	0.00641	Gria4/Nlgn1/Grin2b/Shank2/Tshz3/Nlgn3/Cacng7	7
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	BP	0.238	0.00157	0.00956	2.02	0.0065	Adra1a/P2rx2/Calca/Rps6ka2/Agtr1a	5
GO:0007190	activation of adenylate cyclase activity	BP	0.238	0.00157	0.00956	2.02	0.0065	Vipr2/Adcy3/Calca/Adcy4/Adcy7	5
GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	BP	0.238	0.00157	0.00956	2.02	0.0065	Kdr/Nrp1/Jcad/Hdac9/Akt3	5
GO:0009410	response to xenobiotic stimulus	BP	0.08	0.00159	0.00963	2.02	0.00655	Kcnk3/Cyp1b1/Slc1a3/Sfrp2/Kdr/Adra1a/Abat/Mmp2/Mef2c/Shank2/Htr1b/Ptprm/Fmo1/Ppm1f/Cd38/Igf2/Ppm1e/Htr2a/Nckap1l/Cyp46a1/Gstm7/Gstm1/Dpyd/Abcb1a/Acsl1/Sult1a1	26
GO:0021537	telencephalon development	BP	0.0853	0.00159	0.00963	2.02	0.00655	Lef1/Mdk/Zeb2/Sema7a/Cdh2/Dab1/Lrrk2/Id4/Fut10/Cxcl12/Dnah5/Gli3/Plcb1/Tsku/Dclk2/Lhx6/Rtn4rl1/Nin/Nr2f1/Atp1a2/Fat4/Bbs1	22
GO:0050868	negative regulation of T cell activation	BP	0.105	0.00159	0.00964	2.02	0.00656	Ihh/Mdk/Cd44/Gli3/Loxl3/Btla/H2-Ab1/Havcr2/Nckap1l/Pde5a/H2-Aa/Gimap5/Dlg5/Gimap3	14
GO:0043297	apical junction assembly	BP	0.121	0.00163	0.00985	2.01	0.0067	Wnt11/Cldn8/Cdh5/Abi2/Esam/Pecam1/Snai1/Cldn5/Nphp1/Dlg5/Cldn1	11
GO:0003229	ventricular cardiac muscle tissue development	BP	0.138	0.00163	0.00986	2.01	0.00671	Col11a1/Col14a1/Nog/Lrp2/Ccm2l/Tbx3/Ednra/Myl3/Heg1	9
GO:0060999	positive regulation of dendritic spine development	BP	0.138	0.00163	0.00986	2.01	0.00671	Nlgn1/D16Ertd472e/Nlgn3/Apoe/Caprin2/Bhlhb9/Cux2/Palm/Dlg5	9
GO:0045907	positive regulation of vasoconstriction	BP	0.151	0.00167	0.01	2	0.00683	Adra1a/Icam1/Wdr35/Cd38/Htr2a/Pde5a/Ptger3/Cav1	8
GO:0070169	positive regulation of biomineral tissue development	BP	0.151	0.00167	0.01	2	0.00683	Wnt6/Pkdcc/Slc8a1/Mef2c/Osr2/Nell1/Osr1/Ptn	8
GO:0032413	negative regulation of ion transmembrane transporter activity	BP	0.128	0.00167	0.0101	2	0.00684	Hecw2/Drd4/Dysf/Osr1/Rrad/Pkd2/Gstm7/Atp1a2/Gnb5/Cav1	10
GO:0002087	regulation of respiratory gaseous exchange by nervous system process	BP	0.308	0.0017	0.0101	2	0.00688	Nlgn1/Tshz3/Nlgn3/Atp1a2	4
GO:0010838	positive regulation of keratinocyte proliferation	BP	0.308	0.0017	0.0101	2	0.00688	Mdk/Has2/Stxbp4/Twist2	4
GO:0014052	regulation of gamma-aminobutyric acid secretion	BP	0.308	0.0017	0.0101	2	0.00688	Grik1/Abat/Htr1b/Gabbr1	4
GO:0034374	low-density lipoprotein particle remodeling	BP	0.308	0.0017	0.0101	2	0.00688	Apob/Pla2g10/Apoe/Abcg1	4
GO:0034375	high-density lipoprotein particle remodeling	BP	0.308	0.0017	0.0101	2	0.00688	Pltp/Apoe/Abca5/Abcg1	4
GO:0034392	negative regulation of smooth muscle cell apoptotic process	BP	0.308	0.0017	0.0101	2	0.00688	Gria4/Igf1/Agtr1a/Arrb2	4
GO:0086067	AV node cell to bundle of His cell communication	BP	0.308	0.0017	0.0101	2	0.00688	Cacna1c/Scn4b/Ank2/Gjc1	4
GO:0097090	presynaptic membrane organization	BP	0.308	0.0017	0.0101	2	0.00688	Ptprd/Nlgn1/Nlgn3/Apoe	4
GO:0002313	mature B cell differentiation involved in immune response	BP	0.194	0.00171	0.0101	1.99	0.00688	Itm2a/Dock10/Lfng/Enpp1/Irf8/Mfng	6
GO:0045762	positive regulation of adenylate cyclase activity	BP	0.194	0.00171	0.0101	1.99	0.00688	Cacna1c/Vipr2/Adcy3/Calca/Adcy4/Adcy7	6
GO:0060317	cardiac epithelial to mesenchymal transition	BP	0.194	0.00171	0.0101	1.99	0.00688	Nog/Erg/Has2/Tbx3/Heyl/Snai1	6
GO:2000648	positive regulation of stem cell proliferation	BP	0.194	0.00171	0.0101	1.99	0.00688	Fermt2/Tert/Vegfc/Tbx3/Kitl/Ltbp3	6
GO:0032946	positive regulation of mononuclear cell proliferation	BP	0.101	0.00173	0.0102	1.99	0.00696	Igf1/Mef2c/Tnfsf13b/Cd1d1/Coro1a/Itgal/Il27ra/Cd38/Havcr2/Igf2/Xcl1/Nckap1l/Stat5b/Zap70/Il12rb1	15
GO:0010092	specification of animal organ identity	BP	0.167	0.00179	0.0106	1.98	0.00719	Ar/Wnt11/Hoxd11/Hoxa11/Mef2c/Gli3/Lrp2	7
GO:0090175	regulation of establishment of planar polarity	BP	0.167	0.00179	0.0106	1.98	0.00719	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Fzd2/Dact1	7
GO:0015844	monoamine transport	BP	0.113	0.00181	0.0107	1.97	0.00726	Maob/Slc6a2/Syt13/Abat/Myo5a/Cxcl12/Htr1b/Cadps/Syt7/Htr2a/Ptger3/Gabbr1	12
GO:0048286	lung alveolus development	BP	0.136	0.00182	0.0107	1.97	0.0073	Stra6/Kdr/Igf1/Pkdcc/Foxf1/Hopx/Tcf21/Ltbp3/Selenon	9
GO:0071277	cellular response to calcium ion	BP	0.127	0.00184	0.0109	1.96	0.00738	Nlgn1/Syt13/Cpne5/Mef2c/Rasgrp2/Syt7/Asph/Pkd2/Slc25a23/Smpd1	10
GO:0010038	response to metal ion	BP	0.0814	0.00189	0.0111	1.96	0.00754	Slc13a5/Nlgn1/Syt13/Abat/Cpne5/Fn1/Lrrk2/Nptx1/Mef2c/Rasgrp2/Dlg2/Adcy7/Enpp1/Syt7/Kcnma1/Kcnip3/Asph/Nfatc4/Pkd2/Sord/Slc25a23/Dlg4/Smpd1/Cav1	24
GO:0046545	development of primary female sexual characteristics	BP	0.107	0.00192	0.0112	1.95	0.00765	Angpt1/Kdr/Nos3/Fst/Mmp2/Adamts1/Lfng/Kit/Kitl/Tnfaip6/Arrb1/Arrb2/Stat5b	13
GO:0033135	regulation of peptidyl-serine phosphorylation	BP	0.0964	0.00194	0.0114	1.94	0.00773	Hgf/Sfrp2/Angpt1/Cd44/Hcls1/Pfn2/Prkd1/Tek/Ppm1f/Caprin2/Bdkrb2/Arrb1/Rassf2/Arrb2/Atp2b4/Cav1	16
GO:0048814	regulation of dendrite morphogenesis	BP	0.118	0.00194	0.0114	1.94	0.00773	Ptprz1/Hecw2/Ptprd/Tbc1d24/Obsl1/Trpc6/Caprin2/Sarm1/Nfatc4/Bhlhb9/Cux2	11
GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	BP	0.118	0.00194	0.0114	1.94	0.00773	Gpc6/Drd4/Stx1b/Nptx1/Dlg2/Nptxr/Magi2/Nsg1/Cacng7/Cpt1c/Dlg4	11
GO:0034766	negative regulation of ion transmembrane transport	BP	0.112	0.00196	0.0114	1.94	0.00778	Hecw2/Drd4/Bin1/Dysf/Osr1/Rrad/Ptger3/Pkd2/Gstm7/Atp1a2/Gnb5/Cav1	12
GO:0048791	calcium ion-regulated exocytosis of neurotransmitter	BP	0.227	0.00197	0.0114	1.94	0.00778	Rims3/Stx1b/Cadps/Syt7/Cacna1a	5
GO:0060080	inhibitory postsynaptic potential	BP	0.227	0.00197	0.0114	1.94	0.00778	Grik1/Abat/Drd4/Nlgn3/Grik2	5
GO:0072578	neurotransmitter-gated ion channel clustering	BP	0.227	0.00197	0.0114	1.94	0.00778	Nlgn1/Slitrk3/Glrb/Apoe/Dlg4	5
GO:1900746	regulation of vascular endothelial growth factor signaling pathway	BP	0.227	0.00197	0.0114	1.94	0.00778	Ptp4a3/Jcad/Tcf4/Sema6a/Adgra2	5
GO:0051150	regulation of smooth muscle cell differentiation	BP	0.188	0.00203	0.0118	1.93	0.00801	Tshz3/Zeb1/Kit/Cth/Rbpms2/Efemp2	6
GO:0051965	positive regulation of synapse assembly	BP	0.125	0.00203	0.0118	1.93	0.00801	Ptprd/St8sia2/Nlgn1/Lrrc4b/Adgrl1/Slitrk3/Nlgn3/Bhlhb9/Cux2/Dlg5	10
GO:0030501	positive regulation of bone mineralization	BP	0.163	0.00206	0.0119	1.92	0.00812	Pkdcc/Slc8a1/Mef2c/Osr2/Nell1/Osr1/Ptn	7
GO:0042220	response to cocaine	BP	0.163	0.00206	0.0119	1.92	0.00812	Slc1a3/Abat/Drd4/Htr1b/Htr2a/Dlg4/Smpd1	7
GO:0030278	regulation of ossification	BP	0.102	0.00211	0.0122	1.91	0.00828	Mdk/Pkdcc/Ddr2/Slc8a1/Mef2c/Osr2/Calca/Nell1/Mgp/Enpp1/Ltbp3/P3h1/Osr1/Ptn	14
GO:0031623	receptor internalization	BP	0.102	0.00211	0.0122	1.91	0.00828	Angpt1/Drd4/Calca/Htr1b/Sele/Magi2/Arrb1/Cacng7/Arrb2/Ptger3/Calcrl/Apln/Dlg4/Cav1	14
GO:0050773	regulation of dendrite development	BP	0.102	0.00211	0.0122	1.91	0.00828	Ptprz1/Hecw2/Ptprd/Mark1/Tbc1d24/Obsl1/Trpc6/Caprin2/Sarm1/Nfatc4/Bhlhb9/Cux2/Fat3/Ptn	14
GO:0120193	tight junction organization	BP	0.117	0.00212	0.0122	1.91	0.00831	Wnt11/Mpdz/Cldn8/Cdh5/Esam/Pecam1/Snai1/Svep1/Cldn5/Nphp1/Cldn1	11
GO:0090263	positive regulation of canonical Wnt signaling pathway	BP	0.111	0.00212	0.0122	1.91	0.00831	Sfrp2/Sema5a/Zeb2/Gpc3/Lrrk2/Gprc5b/Peg12/Caprin2/Daam2/Adgra2/Cav1/Dact1	12
GO:0048546	digestive tract morphogenesis	BP	0.145	0.00213	0.0122	1.91	0.00832	Stra6/Ihh/Sfrp2/Foxf1/Gli3/Tcf21/Dact1/Stx2	8
GO:1902476	chloride transmembrane transport	BP	0.145	0.00213	0.0122	1.91	0.00832	Slc1a3/Slc12a8/Ano1/Ano2/Glrb/Gabra4/Slc12a4/Slc4a8	8
GO:0003014	renal system process	BP	0.106	0.00222	0.0127	1.89	0.00867	Cacna1c/Adra1a/Ptpro/Npr3/Ednrb/Stc1/Abcg2/Maged2/Agtr1a/Kcnma1/Ednra/Ptger3/Abcg3	13
GO:0050433	regulation of catecholamine secretion	BP	0.132	0.00225	0.0129	1.89	0.00878	Syt13/Abat/Myo5a/Cxcl12/Htr1b/Syt7/Htr2a/Ptger3/Gabbr1	9
GO:0009312	oligosaccharide biosynthetic process	BP	0.286	0.0023	0.0131	1.88	0.0089	B3galnt1/St3gal2/St6galnac6/St3gal4	4
GO:0030432	peristalsis	BP	0.286	0.0023	0.0131	1.88	0.0089	Tbx2/P2rx2/Tshz3/Tbx3	4
GO:0032341	aldosterone metabolic process	BP	0.286	0.0023	0.0131	1.88	0.0089	Ednrb/Dkk3/Kcnma1/Cacna1h	4
GO:0046058	cAMP metabolic process	BP	0.286	0.0023	0.0131	1.88	0.0089	Adcy3/Adcy4/Adcy7/Cacnb4	4
GO:0051152	positive regulation of smooth muscle cell differentiation	BP	0.286	0.0023	0.0131	1.88	0.0089	Tshz3/Kit/Cth/Efemp2	4
GO:1901201	regulation of extracellular matrix assembly	BP	0.286	0.0023	0.0131	1.88	0.0089	Phldb2/Has2/Emilin1/Tie1	4
GO:1903238	positive regulation of leukocyte tethering or rolling	BP	0.286	0.0023	0.0131	1.88	0.0089	Itga4/Chst2/Sele/St3gal4	4
GO:0010717	regulation of epithelial to mesenchymal transition	BP	0.116	0.00231	0.0131	1.88	0.00892	Sfrp2/Lef1/Mdk/Nog/Mark1/Phldb2/Fermt2/Epha3/Snai1/Spred3/Il17rd	11
GO:1904646	cellular response to amyloid-beta	BP	0.182	0.00239	0.0136	1.87	0.00923	Itga4/Igf1/Cacna2d1/Icam1/Fyn/Cacna1a	6
GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	BP	0.217	0.00243	0.0137	1.86	0.00935	Sema5a/Ppp1r16b/Aplnr/Jcad/Agtr1a	5
GO:0009065	glutamine family amino acid catabolic process	BP	0.217	0.00243	0.0137	1.86	0.00935	Ddah1/Nos3/Asrgl1/Fah/Atp2b4	5
GO:0045668	negative regulation of osteoblast differentiation	BP	0.13	0.00249	0.0141	1.85	0.00957	Nog/Areg/Id3/Gdf10/Vegfc/Rorb/Tnfaip6/Twist2/Ptch1	9
GO:0099601	regulation of neurotransmitter receptor activity	BP	0.13	0.00249	0.0141	1.85	0.00957	Begain/Nlgn1/Nptx1/Mef2c/Nlgn3/Nptxr/Prrt1/Cacng7/Dlg4	9
GO:0051261	protein depolymerization	BP	0.104	0.00256	0.0144	1.84	0.00982	Map2/Sema5a/Evl/Tmod2/Mical1/Rp1/Sh3bp1/Scin/Dysf/Asph/Ttbk2/Nes/Plekhh2	13
GO:0030004	cellular monovalent inorganic cation homeostasis	BP	0.108	0.00267	0.015	1.82	0.0102	Slc1a3/Slc8a1/Lrrk2/Slc9a7/Dmxl2/Kcnma1/Slc9a5/Lacc1/Aqp11/Slc4a3/Atp1a2/Slc4a8	12
GO:1902106	negative regulation of leukocyte differentiation	BP	0.108	0.00267	0.015	1.82	0.0102	Ihh/Mdk/Cd44/Inpp4b/Lrrc17/Gli3/Calca/Flt3/Loxl3/Tnfrsf11b/Zbtb46/Tnfaip6	12
GO:0035567	non-canonical Wnt signaling pathway	BP	0.14	0.00268	0.015	1.82	0.0102	Sfrp2/Wnt11/Nkd1/Gpc3/Znrf3/Daam2/Fzd2/Dact1	8
GO:1900271	regulation of long-term synaptic potentiation	BP	0.14	0.00268	0.015	1.82	0.0102	Eif2ak4/Mme/Nlgn3/Nrgn/Apoe/Nsg1/Cyp46a1/Ptn	8
GO:0001838	embryonic epithelial tube formation	BP	0.0962	0.00271	0.0152	1.82	0.0103	Sfrp2/Wnt6/Nog/Zeb2/Lrp2/Gdf7/Ift57/Cecr2/Prickle1/Ptch1/Ipmk/Osr1/Dlc1/Fzd2/Rab23	15
GO:1902017	regulation of cilium assembly	BP	0.129	0.00275	0.0154	1.81	0.0105	Ccdc88a/Adamts16/Rp1/Kctd17/Crocc/Ttbk2/Dzip1/Dync2li1/Cep97	9
GO:0002092	positive regulation of receptor internalization	BP	0.176	0.0028	0.0156	1.81	0.0106	Angpt1/Sele/Magi2/Arrb1/Arrb2/Apln	6
GO:0051497	negative regulation of stress fiber assembly	BP	0.176	0.0028	0.0156	1.81	0.0106	Kank4/Phldb2/Arhgap6/Tmeff2/Arhgap28/Dlc1	6
GO:0018105	peptidyl-serine phosphorylation	BP	0.0767	0.00284	0.0158	1.8	0.0108	Hgf/Sfrp2/Angpt1/Cd44/Hcls1/Lrrk2/Pfn2/Prkd1/Tek/Rps6ka2/Ppm1f/Caprin2/Dclk2/Bdkrb2/Rps6ka5/Arrb1/Hipk2/Pkd1/Rassf2/Ttbk2/Arrb2/Atp2b4/Akt3/Brsk1/Lats2/Cav1	26
GO:0050848	regulation of calcium-mediated signaling	BP	0.119	0.00292	0.0163	1.79	0.0111	Kdr/Igf1/Drd4/Slc24a4/Lrrk2/Cdh13/Itgal/Cmya5/Atp2b4/Zap70	10
GO:2001259	positive regulation of cation channel activity	BP	0.119	0.00292	0.0163	1.79	0.0111	Cacna2d1/Ank2/Nlgn3/Cracr2a/Ednra/Stac2/Asph/Pkd2/Gstm7/Cacnb4	10
GO:0048675	axon extension	BP	0.0986	0.00294	0.0163	1.79	0.0111	Map2/Sema5a/Sema5b/Sema7a/Nrp1/Fn1/Cxcl12/Edn3/Ndn/Nlgn3/Apoe/Ednra/Sema3g/Sema6a	14
GO:1903531	negative regulation of secretion by cell	BP	0.0925	0.00295	0.0164	1.79	0.0111	Maob/Abat/Drd4/Foxf1/Myo5a/Edn3/Htr1b/Apoe/Cd200/Nckap1l/Cd84/Neo1/Ptger3/Frmd4a/Gabbr1/Nr1h3	16
GO:0009190	cyclic nucleotide biosynthetic process	BP	0.208	0.00296	0.0164	1.79	0.0111	Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7	5
GO:0030903	notochord development	BP	0.208	0.00296	0.0164	1.79	0.0111	Gli1/Wnt11/Nog/Id3/Col13a1	5
GO:0036303	lymph vessel morphogenesis	BP	0.208	0.00296	0.0164	1.79	0.0111	Vash1/Vegfc/Tie1/Pkd1/Svep1	5
GO:0052652	cyclic purine nucleotide metabolic process	BP	0.208	0.00296	0.0164	1.79	0.0111	Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7	5
GO:0043030	regulation of macrophage activation	BP	0.138	0.00299	0.0165	1.78	0.0112	Pla2g10/Lrrk2/Slc7a2/Cd1d1/Havcr2/Cd200/Cd84/Nr1h3	8
GO:1902808	positive regulation of cell cycle G1/S phase transition	BP	0.138	0.00299	0.0165	1.78	0.0112	Gli1/Tbx2/Ddr2/Tert/Ccnd2/Adamts1/Plcb1/Stxbp4	8
GO:0052548	regulation of endopeptidase activity	BP	0.0754	0.00301	0.0166	1.78	0.0113	Hgf/Sfrp2/Spink1/Igf1/Aph1b/Cd44/Bok/Grin2b/Wdr35/Serpine2/Mical1/Ift57/Serpini1/Wnt9a/Ppm1f/Hip1/Bin1/Arrb1/Epha7/Asph/Dlc1/Nlrp1b/Arrb2/Ccn2/Fyn/Mgmt/Cyfip2	27
GO:0002396	MHC protein complex assembly	BP	0.267	0.00303	0.0166	1.78	0.0113	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0002501	peptide antigen assembly with MHC protein complex	BP	0.267	0.00303	0.0166	1.78	0.0113	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0031000	response to caffeine	BP	0.267	0.00303	0.0166	1.78	0.0113	Ryr1/Slc8a1/Selenon/Gstm7	4
GO:0035721	intraciliary retrograde transport	BP	0.267	0.00303	0.0166	1.78	0.0113	Wdr35/Dync2h1/Dync2li1/Bbs1	4
GO:0042693	muscle cell fate commitment	BP	0.267	0.00303	0.0166	1.78	0.0113	AW551984/Tbx2/Mef2c/Tbx3	4
GO:1901386	negative regulation of voltage-gated calcium channel activity	BP	0.267	0.00303	0.0166	1.78	0.0113	Drd4/Dysf/Rrad/Gnb5	4
GO:0017156	calcium-ion regulated exocytosis	BP	0.127	0.00304	0.0166	1.78	0.0113	Syn2/Cacna1c/Syt13/Rims3/Stx1b/Cadps/Syt7/Cacna1h/Cacna1a	9
GO:0048332	mesoderm morphogenesis	BP	0.127	0.00304	0.0166	1.78	0.0113	Sfrp2/Lef1/Wnt11/Nog/Hoxa11/Foxf1/Tbx3/Snai1/Tal1	9
GO:0050818	regulation of coagulation	BP	0.127	0.00304	0.0166	1.78	0.0113	Tfpi/Abat/Serpine2/Procr/Apoe/Pros1/Ptger3/St3gal4/Cav1	9
GO:0042417	dopamine metabolic process	BP	0.152	0.00307	0.0167	1.78	0.0113	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Agtr1a	7
GO:2001258	negative regulation of cation channel activity	BP	0.152	0.00307	0.0167	1.78	0.0113	Drd4/Dysf/Rrad/Pkd2/Gstm7/Gnb5/Cav1	7
GO:0002285	lymphocyte activation involved in immune response	BP	0.0856	0.00307	0.0167	1.78	0.0113	Lef1/Mdk/Itm2a/Icam1/Eif2ak4/Dock10/Lfng/Loxl3/Coro1a/Itgal/Il27ra/Cracr2a/Enpp1/Havcr2/Irf8/Nckap1l/Mfng/Rab27a/Apbb1ip	19
GO:1903707	negative regulation of hemopoiesis	BP	0.106	0.0031	0.0169	1.77	0.0115	Ihh/Mdk/Cd44/Inpp4b/Lrrc17/Gli3/Calca/Flt3/Loxl3/Tnfrsf11b/Zbtb46/Tnfaip6	12
GO:0042471	ear morphogenesis	BP	0.0979	0.00313	0.017	1.77	0.0116	Col11a1/Nog/Tbx2/Osr2/Tshz1/Lrig3/Zeb1/Enpp1/Tbx3/Ednra/Osr1/Fzd2/Kcnq4/Itga8	14
GO:0048640	negative regulation of developmental growth	BP	0.102	0.00315	0.0171	1.77	0.0116	Map2/Sema5a/H19/Nog/Sema5b/Nkd1/Sema7a/Nrp1/Sema3g/Epha7/Ptch1/Pi16/Sema6a	13
GO:0034103	regulation of tissue remodeling	BP	0.118	0.00319	0.0173	1.76	0.0118	Mdk/Ddr2/Inpp4b/Erg/Calca/Tnfrsf11b/Cd38/Syt7/Ltbp3/Abi3bp	10
GO:0019935	cyclic-nucleotide-mediated signaling	BP	0.111	0.00319	0.0173	1.76	0.0118	Gnai1/Ednrb/Gucy1a2/Gucy1b1/Gucy1a1/Aplnr/Apoe/Adcyap1r1/Cap2/Rasd2/Ptger3	11
GO:0042908	xenobiotic transport	BP	0.171	0.00326	0.0176	1.75	0.012	Abcg2/Abca8b/Abcb1a/Abcc5/Abcg3/Cldn1	6
GO:0090162	establishment of epithelial cell polarity	BP	0.171	0.00326	0.0176	1.75	0.012	Foxf1/Msn/Myo9a/Sh3bp1/Frmd4b/Frmd4a	6
GO:0071902	positive regulation of protein serine/threonine kinase activity	BP	0.087	0.00328	0.0177	1.75	0.0121	Igf1/Zeb2/Drd4/Fermt2/Ccnd2/Lrrk2/Edn3/Pik3r6/Kit/Nox4/Htr2a/Kitl/Pkd1/Pde5a/Pkd2/Atp2b4/Acsl1/C1qtnf9	18
GO:0031532	actin cytoskeleton reorganization	BP	0.105	0.00334	0.0179	1.75	0.0122	Hmcn1/Mdk/Nrp1/Thsd7b/Tek/Syde1/Kit/Esam/Parvg/Carmil3/Efs/Parvb	12
GO:0045778	positive regulation of ossification	BP	0.136	0.00334	0.0179	1.75	0.0122	Pkdcc/Slc8a1/Mef2c/Osr2/Calca/Nell1/Osr1/Ptn	8
GO:0071622	regulation of granulocyte chemotaxis	BP	0.136	0.00334	0.0179	1.75	0.0122	Mdk/Jam3/Ednra/Xcl1/Nckap1l/Tnfaip6/Dysf/Mpp1	8
GO:0007405	neuroblast proliferation	BP	0.125	0.00334	0.0179	1.75	0.0122	Acsl6/Hhip/Lef1/Lrrk2/Id4/Gli3/Eml1/Vegfc/Ptn	9
GO:0045428	regulation of nitric oxide biosynthetic process	BP	0.125	0.00334	0.0179	1.75	0.0122	Igf1/Ddah1/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	9
GO:0048168	regulation of neuronal synaptic plasticity	BP	0.125	0.00334	0.0179	1.75	0.0122	Grik1/Kdr/Nog/Grin2b/Kit/Grik2/Dlg4/Syngap1/Cpeb1	9
GO:2000179	positive regulation of neural precursor cell proliferation	BP	0.125	0.00334	0.0179	1.75	0.0122	Gli1/Mdk/Nog/Igf1/Zfp423/Gli3/Lrp2/Vegfc/Nes	9
GO:0014013	regulation of gliogenesis	BP	0.101	0.00338	0.0181	1.74	0.0123	Ptprz1/Mdk/Nog/Igf1/Tert/Dab1/Id4/Serpine2/Lrp2/Daam2/Bin1/Zcchc24/Ptn	13
GO:0031348	negative regulation of defense response	BP	0.083	0.00345	0.0184	1.73	0.0125	Hgf/Acod1/Mdk/Pla2g10/Igf1/Cd44/Ets1/Foxf1/Fndc4/Cdh5/Apoe/Havcr2/Cd200/Igf2/Tnfaip6/Mapkbp1/Arrb2/Calcrl/Cd96/Nr1h3	20
GO:0006865	amino acid transport	BP	0.0938	0.00345	0.0184	1.73	0.0125	Slc1a3/Grik1/Abat/Slc7a2/Grin2b/Slc36a4/Htr1b/Slc6a15/Sfxn5/Nfkbie/Slc38a1/Slc7a7/Gabbr1/Cacna1a/Cacnb4	15
GO:0006885	regulation of pH	BP	0.11	0.00345	0.0184	1.73	0.0125	Car4/Ednrb/Lrrk2/Slc9a7/Dmxl2/Agtr1a/Slc9a5/Lacc1/Aqp11/Slc4a3/Slc4a8	11
GO:0003016	respiratory system process	BP	0.149	0.00347	0.0185	1.73	0.0126	Nlgn1/Tshz3/Jag2/Ndn/Nlgn3/Selenon/Atp1a2	7
GO:0060415	muscle tissue morphogenesis	BP	0.116	0.00347	0.0185	1.73	0.0126	Col11a1/Angpt1/Nog/Lrp2/Ccm2l/Ednra/Myl3/Heg1/Fzd2/Efemp2	10
GO:0051896	regulation of protein kinase B signaling	BP	0.0909	0.0035	0.0186	1.73	0.0127	Sema5a/Angpt1/Igf1/Hcls1/Fermt2/Inpp4b/Tek/Cxcl12/Lrp2/Nox4/Magi2/Igf2/Cavin3/Rcn3/Rasd2/Arrb2	16
GO:0007413	axonal fasciculation	BP	0.2	0.00357	0.0189	1.72	0.0129	Ptprz1/Sema5a/Nrp1/Ndn/Epha3	5
GO:0010996	response to auditory stimulus	BP	0.2	0.00357	0.0189	1.72	0.0129	Stra6/Slc1a3/Mdk/Atp1a2/Ptn	5
GO:0035024	negative regulation of Rho protein signal transduction	BP	0.2	0.00357	0.0189	1.72	0.0129	Adra1a/Rasip1/Arap3/Heg1/Dlc1	5
GO:0106030	neuron projection fasciculation	BP	0.2	0.00357	0.0189	1.72	0.0129	Ptprz1/Sema5a/Nrp1/Ndn/Epha3	5
GO:2000311	regulation of AMPA receptor activity	BP	0.2	0.00357	0.0189	1.72	0.0129	Nlgn1/Mef2c/Nlgn3/Prrt1/Cacng7	5
GO:0002573	myeloid leukocyte differentiation	BP	0.0826	0.00361	0.0191	1.72	0.013	Lef1/Cd109/Hcls1/Gpc3/Mef2c/Inpp4b/Lrrc17/Calca/Plcb1/Kit/Tnfrsf11b/Enpp1/Zbtb46/Tal1/Kitl/Tnfaip6/Rassf2/Nrros/Gimap5/Gimap3	20
GO:0051146	striated muscle cell differentiation	BP	0.0762	0.00366	0.0193	1.71	0.0132	AW551984/Sgcd/Col14a1/Ryr1/Igf1/Adra1a/Slc8a1/P2rx2/Tmod2/Cdh2/Mef2c/Cxcl12/Hopx/Nox4/Tbx3/Igf2/Hdac9/Dysf/Flnc/Selenon/Arrb2/Neo1/Pi16/Sgcb/Plekho1	25
GO:0001541	ovarian follicle development	BP	0.123	0.00367	0.0194	1.71	0.0132	Angpt1/Kdr/Mmp2/Lfng/Kit/Kitl/Tnfaip6/Arrb1/Arrb2	9
GO:0043954	cellular component maintenance	BP	0.123	0.00367	0.0194	1.71	0.0132	Epb41l3/Fermt2/Grin2b/Shank2/Apoe/Erc2/Fyn/Syngap1/Cldn1	9
GO:0042987	amyloid precursor protein catabolic process	BP	0.133	0.00371	0.0195	1.71	0.0133	Igf1/Aph1b/Rtn1/Slc2a13/Apoe/Bin1/Abcg1/Adam19	8
GO:0050772	positive regulation of axonogenesis	BP	0.109	0.00373	0.0196	1.71	0.0134	Sema5a/Plxnb1/Zeb2/Sema7a/Nrp1/Fn1/Cxcl12/Plxnd1/Apoe/Nin/Chodl	11
GO:0032410	negative regulation of transporter activity	BP	0.115	0.00378	0.0198	1.7	0.0135	Hecw2/Drd4/Dysf/Osr1/Rrad/Pkd2/Gstm7/Atp1a2/Gnb5/Cav1	10
GO:0060411	cardiac septum morphogenesis	BP	0.115	0.00378	0.0198	1.7	0.0135	Wnt11/Nog/Tbx2/Nos3/Nrp1/Lrp2/Aplnr/Tbx3/Heyl/Fzd2	10
GO:0046777	protein autophosphorylation	BP	0.0823	0.00379	0.0199	1.7	0.0135	Epha8/Kdr/Ddr2/Lrrk2/Prkd1/Itk/Tek/Stk33/Eif2ak4/Flt3/Thy1/Kit/Vegfc/Enpp1/Epha7/Rassf2/Fyn/Fgr/Zap70/Cav1	20
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	BP	0.0857	0.00382	0.02	1.7	0.0136	Hgf/Sfrp2/Igf1/Cd44/Bok/Wdr35/Mical1/Ift57/Wnt9a/Ppm1f/Hip1/Arrb1/Epha7/Dlc1/Nlrp1b/Arrb2/Ccn2/Mgmt	18
GO:0019751	polyol metabolic process	BP	0.103	0.00385	0.0201	1.7	0.0137	Inpp4b/Sptlc3/Plcb1/Pth1r/Plpp3/Bpnt1/Adcyap1r1/Degs2/Dysf/Ipmk/Sord/Plpp1	12
GO:0051952	regulation of amine transport	BP	0.103	0.00385	0.0201	1.7	0.0137	Grik1/Syt13/Abat/Myo5a/Grin2b/Cxcl12/Htr1b/Syt7/Htr2a/Ptger3/Gabbr1/Cacna1a	12
GO:0008212	mineralocorticoid metabolic process	BP	0.25	0.0039	0.0203	1.69	0.0138	Ednrb/Dkk3/Kcnma1/Cacna1h	4
GO:0031650	regulation of heat generation	BP	0.25	0.0039	0.0203	1.69	0.0138	Abat/Ednrb/Ptger3/Apln	4
GO:0034433	steroid esterification	BP	0.25	0.0039	0.0203	1.69	0.0138	Soat1/Apoe/Agtr1a/Abcg1	4
GO:0034434	sterol esterification	BP	0.25	0.0039	0.0203	1.69	0.0138	Soat1/Apoe/Agtr1a/Abcg1	4
GO:0034435	cholesterol esterification	BP	0.25	0.0039	0.0203	1.69	0.0138	Soat1/Apoe/Agtr1a/Abcg1	4
GO:0043084	penile erection	BP	0.25	0.0039	0.0203	1.69	0.0138	Ar/Drd4/Ednrb/Ednra	4
GO:0044065	regulation of respiratory system process	BP	0.25	0.0039	0.0203	1.69	0.0138	Nlgn1/Tshz3/Nlgn3/Atp1a2	4
GO:0001890	placenta development	BP	0.0899	0.00391	0.0203	1.69	0.0138	Ndp/Lef1/Itga4/Slc8a1/Il11ra1/Vash1/Syde1/Prdm1/Pcdh12/Cdkn1c/Igf2/Snai1/Pkd1/Pkd2/Ptn/Vash2	16
GO:0030517	negative regulation of axon extension	BP	0.146	0.00392	0.0203	1.69	0.0138	Map2/Sema5a/Sema5b/Sema7a/Nrp1/Sema3g/Sema6a	7
GO:0032965	regulation of collagen biosynthetic process	BP	0.146	0.00392	0.0203	1.69	0.0138	Ihh/Ddr2/Fn1/Emilin1/Arrb2/Ccn2/Cygb	7
GO:0034205	amyloid-beta formation	BP	0.146	0.00392	0.0203	1.69	0.0138	Igf1/Aph1b/Rtn1/Slc2a13/Apoe/Bin1/Abcg1	7
GO:0048010	vascular endothelial growth factor receptor signaling pathway	BP	0.146	0.00392	0.0203	1.69	0.0138	Angpt1/Kdr/Nrp1/Prkd1/Tek/Vegfc/Emilin1	7
GO:0071214	cellular response to abiotic stimulus	BP	0.0758	0.00396	0.0204	1.69	0.0139	Sfrp2/Wnt11/Nos3/Ccnd2/Slc24a4/Mmp2/Eif2ak4/Mme/Scn2a/Rp1/Ednra/Bdkrb2/Cnn2/Dysf/Nfatc4/Net1/Pkd2/Slc25a23/Palm/Atp1a2/Gnb5/Habp4/Smpd1/Piezo2/Cav1	25
GO:0104004	cellular response to environmental stimulus	BP	0.0758	0.00396	0.0204	1.69	0.0139	Sfrp2/Wnt11/Nos3/Ccnd2/Slc24a4/Mmp2/Eif2ak4/Mme/Scn2a/Rp1/Ednra/Bdkrb2/Cnn2/Dysf/Nfatc4/Net1/Pkd2/Slc25a23/Palm/Atp1a2/Gnb5/Habp4/Smpd1/Piezo2/Cav1	25
GO:0016485	protein processing	BP	0.0791	0.00397	0.0205	1.69	0.0139	Cpxm2/Ihh/Mmp16/Aph1b/Lrrk2/Serpine2/Gli3/Rps6ka2/Cpe/Mme/C1rl/Ldlrad3/Dync2h1/Pcsk5/C1ra/Ptch1/Asph/Ece2/Adam19/Arxes2/Cyfip2/Nkd2	22
GO:0001708	cell fate specification	BP	0.108	0.00403	0.0207	1.68	0.0141	Ihh/Sfrp2/Ar/Wnt11/Hoxd10/Ptch2/Tbx2/Hoxa11/Gli3/Tbx3/Ptch1	11
GO:0051346	negative regulation of hydrolase activity	BP	0.0738	0.00405	0.0208	1.68	0.0142	Hgf/Sfrp2/Cd109/Spink1/Igf1/Tfpi/Nos3/Cd44/Gpc3/Lrrk2/Serpine2/Mical1/Wfdc3/Serpini1/Wnt9a/Pecam1/Nckap1l/Cmya5/Bin1/Hdac9/Arrb1/Arrb2/Pi16/Angptl4/Pi15/Ppp1r26/Simc1	27
GO:0021675	nerve development	BP	0.114	0.00411	0.021	1.68	0.0143	Slc1a3/Itga4/Rnf165/Nrp1/Slc24a4/Nptx1/Serpine2/Gli3/Hoxd3/Ednra	10
GO:0120192	tight junction assembly	BP	0.114	0.00411	0.021	1.68	0.0143	Wnt11/Mpdz/Cldn8/Cdh5/Esam/Pecam1/Snai1/Cldn5/Nphp1/Cldn1	10
GO:0021543	pallium development	BP	0.092	0.00411	0.021	1.68	0.0143	Lef1/Mdk/Zeb2/Cdh2/Dab1/Id4/Fut10/Gli3/Plcb1/Tsku/Dclk2/Lhx6/Nr2f1/Fat4/Bbs1	15
GO:0007368	determination of left/right symmetry	BP	0.0985	0.00411	0.021	1.68	0.0143	Ihh/Tbx2/Foxf1/Mef2c/Dnah5/Ift57/Aplnr/Tbx3/Dync2h1/Daam2/Pcsk5/Pkd2/Dync2li1	13
GO:0042551	neuron maturation	BP	0.131	0.00412	0.021	1.68	0.0143	Epha8/Cspg4/Ednrb/Lrrk2/Dlg2/Cdkn1c/Nfasc/Ednra	8
GO:0140115	export across plasma membrane	BP	0.131	0.00412	0.021	1.68	0.0143	Kcnd3/Slc8a1/Slc24a4/Abcg2/Slc8a3/Atp1a2/Abcb1a/Abcc5	8
GO:0030859	polarized epithelial cell differentiation	BP	0.192	0.00427	0.0218	1.66	0.0148	Foxf1/Msn/Myo9a/Sh3bp1/Dlg5	5
GO:0043171	peptide catabolic process	BP	0.192	0.00427	0.0218	1.66	0.0148	Enpep/Cpe/Trhde/Ggt7/Lvrn	5
GO:0060065	uterus development	BP	0.192	0.00427	0.0218	1.66	0.0148	Stra6/Hoxa11/Hoxa10/Cdkn1c/Hoxa9	5
GO:0030593	neutrophil chemotaxis	BP	0.107	0.00434	0.0221	1.66	0.015	Cxcl15/Mdk/Jam3/Edn3/Itga1/Ednra/Xcl1/Nckap1l/Tnfaip6/Dysf/Mpp1	11
GO:2001234	negative regulation of apoptotic signaling pathway	BP	0.0813	0.00434	0.0221	1.66	0.015	Hgf/Sfrp2/Ar/Agap2/Nog/Igf1/Cd44/Nrp1/Tert/Bok/Lrrk2/Icam1/Cxcl12/Mapk8ip1/Tnfrsf22/Cth/Snai1/Bdkrb2/Arrb2/Fyn	20
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	BP	0.162	0.00434	0.0221	1.66	0.015	Igf1/Ddr2/Tert/Mmp2/Adamts1/Htr1b	6
GO:0010952	positive regulation of peptidase activity	BP	0.0889	0.00436	0.0221	1.65	0.0151	Sfrp2/Aph1b/Bok/Grin2b/Wdr35/Ift57/Ppm1f/Hip1/Arrb1/Rcn3/Asph/Dlc1/Nlrp1b/Ccn2/Fyn/Cyfip2	16
GO:0046633	alpha-beta T cell proliferation	BP	0.143	0.00441	0.0224	1.65	0.0152	Cd44/Mapk8ip1/Dock2/Btla/Xcl1/Zap70/Il12rb1	7
GO:0051897	positive regulation of protein kinase B signaling	BP	0.102	0.00442	0.0224	1.65	0.0152	Sema5a/Angpt1/Igf1/Hcls1/Fermt2/Tek/Cxcl12/Lrp2/Nox4/Igf2/Rasd2/Arrb2	12
GO:1902115	regulation of organelle assembly	BP	0.0845	0.00443	0.0225	1.65	0.0153	Gap43/Fez1/Ptprd/Ccdc88a/Adamts16/Lrrc4b/Lrrk2/Nptx1/Msn/Rp1/Kctd17/Nptxr/Crocc/Ttbk2/Dzip1/Dync2li1/Arhgef9/Cep97	18
GO:0045638	negative regulation of myeloid cell differentiation	BP	0.112	0.00445	0.0225	1.65	0.0153	Inpp4b/Lrrc17/Calca/Tnfrsf11b/Gpr171/Zbtb46/Hoxa9/Tnfaip6/Twist2/Stat5b	10
GO:0045444	fat cell differentiation	BP	0.0795	0.00454	0.0229	1.64	0.0156	Sfrp2/Igf1/Lama4/Fermt2/Runx1t1/Vstm2a/Arl6/Id4/Bbs7/Glis1/Plcb1/Sh2b2/Gdf10/Enpp1/Htr2a/Dysf/Lrp3/Arxes2/Steap4/Bbs1/Dact1	21
GO:0010770	positive regulation of cell morphogenesis involved in differentiation	BP	0.106	0.00467	0.0236	1.63	0.016	Mdk/Ptprd/Nrp1/Fermt2/Has2/Tbc1d24/Obsl1/Caprin2/Net1/Bhlhb9/Cux2	11
GO:0001841	neural tube formation	BP	0.097	0.00467	0.0236	1.63	0.016	Sfrp2/Nog/Zeb2/Lrp2/Gdf7/Ift57/Cecr2/Prickle1/Ptch1/Ipmk/Dlc1/Fzd2/Rab23	13
GO:0050764	regulation of phagocytosis	BP	0.101	0.00473	0.0238	1.62	0.0162	Tub/Dock2/Syt7/Pros1/Masp1/Cnn2/Nckap1l/Dysf/Clec7a/Fgr/Rab27a/Il2rg	12
GO:0007259	receptor signaling pathway via JAK-STAT	BP	0.0859	0.00477	0.024	1.62	0.0163	Stra6/Cyp1b1/Agap2/Ptprd/Igf1/Hcls1/Dab1/Kit/Agtr1a/Pecam1/Pkd1/Csf2rb/Fyn/Pkd2/Stat5b/Il12rb1/Cav1	17
GO:0021766	hippocampus development	BP	0.118	0.00482	0.0242	1.62	0.0164	Lef1/Mdk/Zeb2/Dab1/Id4/Gli3/Tsku/Dclk2/Bbs1	9
GO:0046847	filopodium assembly	BP	0.118	0.00482	0.0242	1.62	0.0164	Gap43/Nlgn1/Nrp1/Sh3bp1/Daam2/Fgd1/Palm/Dpysl3/Itgb4	9
GO:0080164	regulation of nitric oxide metabolic process	BP	0.118	0.00482	0.0242	1.62	0.0164	Igf1/Ddah1/Icam1/Wdr35/Pkd2/Atp2b4/Gimap5/Gimap3/Cav1	9
GO:0035148	tube formation	BP	0.0879	0.00485	0.0243	1.61	0.0165	Sfrp2/Wnt6/Nog/Zeb2/Lrp2/Gdf7/Ift57/Cecr2/Prickle1/Ptch1/Ipmk/Osr1/Dlc1/Fzd2/Rab23/Edar	16
GO:0001845	phagolysosome assembly	BP	0.235	0.00493	0.0245	1.61	0.0167	Rab34/Srpx/Coro1a/Syt7	4
GO:0006491	N-glycan processing	BP	0.235	0.00493	0.0245	1.61	0.0167	St8sia2/St8sia4/Man2a2/St8sia6	4
GO:0035337	fatty-acyl-CoA metabolic process	BP	0.235	0.00493	0.0245	1.61	0.0167	Acsl6/Them5/Acot7/Acsl1	4
GO:0042756	drinking behavior	BP	0.235	0.00493	0.0245	1.61	0.0167	Slc24a4/Htr1b/Agtr1a/Apln	4
GO:0045059	positive thymic T cell selection	BP	0.235	0.00493	0.0245	1.61	0.0167	Cd3g/Dock2/Cd1d1/Zap70	4
GO:0061000	negative regulation of dendritic spine development	BP	0.235	0.00493	0.0245	1.61	0.0167	Nlgn1/Nlgn3/Apoe/Ngef	4
GO:0070571	negative regulation of neuron projection regeneration	BP	0.235	0.00493	0.0245	1.61	0.0167	Thy1/Rtn4rl1/Neo1/Xylt1	4
GO:0090136	epithelial cell-cell adhesion	BP	0.235	0.00493	0.0245	1.61	0.0167	Ihh/Cyp1b1/Kit/Svep1	4
GO:0097094	craniofacial suture morphogenesis	BP	0.235	0.00493	0.0245	1.61	0.0167	Mmp16/Gli3/Frem1/Rab23	4
GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	BP	0.235	0.00493	0.0245	1.61	0.0167	Ppp1r16b/Aplnr/Jcad/Agtr1a	4
GO:0050819	negative regulation of coagulation	BP	0.14	0.00494	0.0245	1.61	0.0167	Tfpi/Abat/Serpine2/Procr/Apoe/Pros1/Ptger3	7
GO:0006898	receptor-mediated endocytosis	BP	0.0789	0.00494	0.0245	1.61	0.0167	Angpt1/Itga4/Drd4/Clec9a/Calca/Lrp2/Htr1b/Nlgn3/Apoe/Sele/Ldlrad3/Magi2/Hip1/Arrb1/Cacng7/Arrb2/Ptger3/Calcrl/Apln/Dlg4/Cav1	21
GO:0007212	dopamine receptor signaling pathway	BP	0.158	0.00498	0.0246	1.61	0.0167	Nsg2/Drd4/Lrrk2/Nsg1/Palm/Gnb5	6
GO:0045589	regulation of regulatory T cell differentiation	BP	0.158	0.00498	0.0246	1.61	0.0167	Mdk/Cd44/Sox12/Gimap5/Gimap3/Il2rg	6
GO:0098868	bone growth	BP	0.158	0.00498	0.0246	1.61	0.0167	Kdr/Ddr2/Evc/Thbs3/Stc1/Enpp1	6
GO:1902003	regulation of amyloid-beta formation	BP	0.158	0.00498	0.0246	1.61	0.0167	Igf1/Rtn1/Slc2a13/Apoe/Bin1/Abcg1	6
GO:0010517	regulation of phospholipase activity	BP	0.127	0.00503	0.0247	1.61	0.0168	Adra1a/Itk/Arhgap6/Sele/Agtr1a/Adcyap1r1/Htr2a/Dlc1	8
GO:0035306	positive regulation of dephosphorylation	BP	0.127	0.00503	0.0247	1.61	0.0168	Npnt/Mef2c/Itga1/Cdh5/Ppp1r16b/Magi2/Dlc1/Smpd1	8
GO:0042269	regulation of natural killer cell mediated cytotoxicity	BP	0.127	0.00503	0.0247	1.61	0.0168	Pik3r6/Cd226/Havcr2/Igf2/Arrb2/Stat5b/Gimap5/Gimap3	8
GO:0045744	negative regulation of G protein-coupled receptor signaling pathway	BP	0.127	0.00503	0.0247	1.61	0.0168	Calca/Htr1b/Aplnr/Arrb1/Arrb2/Ptger3/Apln/Atp2b4	8
GO:0007498	mesoderm development	BP	0.1	0.00506	0.0248	1.61	0.0169	Sfrp2/Lef1/Wnt11/Nog/Hoxa11/Foxf1/Tbx3/Snai1/Tal1/Osr1/Pus7/Ets2	12
GO:0042104	positive regulation of activated T cell proliferation	BP	0.185	0.00506	0.0248	1.61	0.0169	Igf1/Il27ra/Igf2/Stat5b/Il12rb1	5
GO:0062009	secondary palate development	BP	0.185	0.00506	0.0248	1.61	0.0169	Lef1/Wnt11/Tshz1/Jag2/Fzd2	5
GO:0072012	glomerulus vasculature development	BP	0.185	0.00506	0.0248	1.61	0.0169	Angpt1/Tek/Tcf21/Ednra/Osr1	5
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	BP	0.0927	0.00511	0.025	1.6	0.017	Adra1a/Adgrl4/Cxcr3/Adcy3/Ptgfr/Adgrl1/Calca/Pth1r/Adcy4/Gpr161/Adcy7/Ptger3/Calcrl/Atp2b4	14
GO:0071674	mononuclear cell migration	BP	0.0874	0.00511	0.025	1.6	0.017	Mdk/Itga4/Cyp7b1/Ptpro/Itgb7/Icam1/Cxcr3/Cxcl12/Calca/Plcb1/Msn/Itgal/Il27ra/Cd200/Pecam1/Xcl1	16
GO:0030258	lipid modification	BP	0.0833	0.00512	0.0251	1.6	0.017	Acacb/Soat1/Inpp4b/Agk/Bdh2/Plpp3/St3gal2/Dgkb/Ggta1/Apoe/Agtr1a/Abcg1/Echs1/Abcd2/Plpp1/St3gal4/Cygb/C1qtnf9	18
GO:0072175	epithelial tube formation	BP	0.0898	0.00514	0.0251	1.6	0.0171	Sfrp2/Wnt6/Nog/Zeb2/Lrp2/Gdf7/Ift57/Cecr2/Prickle1/Ptch1/Ipmk/Osr1/Dlc1/Fzd2/Rab23	15
GO:0008277	regulation of G protein-coupled receptor signaling pathway	BP	0.0956	0.00529	0.0258	1.59	0.0176	Tub/Tmod2/Slc24a4/Calca/Plcb1/Htr1b/Aplnr/Arrb1/Pde5a/Arrb2/Ptger3/Apln/Atp2b4	13
GO:0032886	regulation of microtubule-based process	BP	0.0784	0.00538	0.0262	1.58	0.0178	Map2/Fez1/Phldb2/Mpdz/Gnai1/Cdh5/Epha3/Rp1/Map9/Tubb4a/Slain1/Nin/Pkd1/Dysf/Ttbk2/Klhl42/Cep97/Bbs1/Mapre2/Cav1/Tppp	21
GO:0072521	purine-containing compound metabolic process	BP	0.0714	0.00538	0.0262	1.58	0.0178	Ttr/Nme4/Acsl6/Igf1/Hmgcs2/Nos3/Acacb/Lrrk2/Adcy3/Gamt/Them5/Gucy1b1/Gucy1a1/Dhtkd1/Adcy4/Adcy7/Enpp1/Lacc1/Htr2a/Acot7/Zbtb20/Pde5a/Dpyd/Rab23/Impdh1/Acsl1/Pid1/Cacnb4	28
GO:0015837	amine transport	BP	0.0992	0.0054	0.0263	1.58	0.0179	Grik1/Syt13/Abat/Myo5a/Grin2b/Cxcl12/Htr1b/Syt7/Htr2a/Ptger3/Gabbr1/Cacna1a	12
GO:0044106	cellular amine metabolic process	BP	0.0992	0.0054	0.0263	1.58	0.0179	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Hdc/Agtr1a/Ednra/Atp2b4/Slc7a7/Sult1a1	12
GO:0006687	glycosphingolipid metabolic process	BP	0.137	0.00552	0.0268	1.57	0.0182	St8sia2/St8sia4/St6galnac4/St3gal2/Kit/St8sia6/St6galnac6	7
GO:0042088	T-helper 1 type immune response	BP	0.137	0.00552	0.0268	1.57	0.0182	Lef1/Il27ra/H2-Ab1/Cracr2a/Havcr2/Xcl1/Il12rb1	7
GO:0097581	lamellipodium organization	BP	0.109	0.00564	0.0274	1.56	0.0186	Ptpro/Ccdc88a/Cd44/Wasf3/Abi3/Cdh13/Abi2/Kit/Parvb/Plekho1	10
GO:0002335	mature B cell differentiation	BP	0.154	0.00567	0.0274	1.56	0.0187	Itm2a/Dock10/Lfng/Enpp1/Irf8/Mfng	6
GO:0033238	regulation of cellular amine metabolic process	BP	0.154	0.00567	0.0274	1.56	0.0187	Maob/Abat/Drd4/Pde1b/Atp2b4/Slc7a7	6
GO:0051481	negative regulation of cytosolic calcium ion concentration	BP	0.154	0.00567	0.0274	1.56	0.0187	Kcnk3/Slc8a1/Calca/Pkd2/Gstm7/Atp1a2	6
GO:0070570	regulation of neuron projection regeneration	BP	0.154	0.00567	0.0274	1.56	0.0187	Hgf/Thy1/Rtn4rl1/Neo1/Xylt1/Ptn	6
GO:0010769	regulation of cell morphogenesis involved in differentiation	BP	0.0984	0.00577	0.0278	1.56	0.0189	Mdk/Ptprd/Nrp1/Fermt2/Has2/Tbc1d24/Obsl1/Postn/Caprin2/Net1/Bhlhb9/Cux2	12
GO:0006821	chloride transport	BP	0.103	0.00579	0.0279	1.55	0.019	Slc1a3/Slc12a8/Ano1/Ano2/Ttyh2/Glrb/Gabra4/Slc12a4/Clca2/Abcb1a/Slc4a8	11
GO:0009314	response to radiation	BP	0.0696	0.00584	0.0281	1.55	0.0191	Slc1a3/Sfrp2/Sema5a/Cacna1c/Nog/Sema5b/Ccnd2/Slc24a4/Mmp2/B4galt2/Pde1b/Cacna1e/Lrp2/Eif2ak4/Fbxl21/Mme/Kit/Rp1/Nlgn3/Arrb1/Nfatc4/Net1/Atp1a2/Gnb5/Brsk1/Syngap1/Smpd1/Ddhd2/Usp2/Cacnb4	30
GO:0034390	smooth muscle cell apoptotic process	BP	0.179	0.00595	0.0285	1.54	0.0194	Gria4/Igf1/Agtr1a/Arrb1/Arrb2	5
GO:0034391	regulation of smooth muscle cell apoptotic process	BP	0.179	0.00595	0.0285	1.54	0.0194	Gria4/Igf1/Agtr1a/Arrb1/Arrb2	5
GO:1903055	positive regulation of extracellular matrix organization	BP	0.179	0.00595	0.0285	1.54	0.0194	Sema5a/Ddr2/Phldb2/Emilin1/Efemp2	5
GO:1904706	negative regulation of vascular associated smooth muscle cell proliferation	BP	0.179	0.00595	0.0285	1.54	0.0194	Drd4/Mef2c/Rgs5/Apln/Efemp2	5
GO:0010950	positive regulation of endopeptidase activity	BP	0.0882	0.00605	0.029	1.54	0.0197	Sfrp2/Aph1b/Bok/Grin2b/Wdr35/Ift57/Ppm1f/Hip1/Arrb1/Asph/Dlc1/Nlrp1b/Ccn2/Fyn/Cyfip2	15
GO:0009247	glycolipid biosynthetic process	BP	0.123	0.00608	0.0291	1.54	0.0198	St8sia2/St8sia4/St6galnac4/St3gal2/St8sia6/Sccpdh/St6galnac6/St3gal4	8
GO:0071260	cellular response to mechanical stimulus	BP	0.123	0.00608	0.0291	1.54	0.0198	Wnt11/Nos3/Ednra/Cnn2/Atp1a2/Habp4/Piezo2/Cav1	8
GO:0044272	sulfur compound biosynthetic process	BP	0.108	0.00608	0.0291	1.54	0.0198	Acsl6/Angpt1/Cbs/Acacb/Chst1/Cth/Xylt1/Dse/Ggt7/Acsl1	10
GO:0006469	negative regulation of protein kinase activity	BP	0.0837	0.0061	0.0292	1.54	0.0198	Sfrp2/Ptpro/Slc8a1/Mapk8ip1/Slc8a3/Pkia/Thy1/Ppm1f/Cdkn1c/Apoe/Rasip1/Ppm1e/Pkib/Heg1/Lats2/Smpd1/Cav1	17
GO:0010470	regulation of gastrulation	BP	0.222	0.00613	0.0292	1.54	0.0198	Phldb2/Osr2/Tgif2/Osr1	4
GO:0015701	bicarbonate transport	BP	0.222	0.00613	0.0292	1.54	0.0198	Car4/Ptger3/Slc4a3/Slc4a8	4
GO:0033631	cell-cell adhesion mediated by integrin	BP	0.222	0.00613	0.0292	1.54	0.0198	Itga4/Npnt/Podxl/Plpp3	4
GO:0035633	maintenance of blood-brain barrier	BP	0.222	0.00613	0.0292	1.54	0.0198	Angpt1/Bdkrb2/Cldn5/Abcb1a	4
GO:0061430	bone trabecula morphogenesis	BP	0.222	0.00613	0.0292	1.54	0.0198	Plxnb1/Thbs3/Mmp2/Enpp1	4
GO:0090279	regulation of calcium ion import	BP	0.135	0.00615	0.0292	1.53	0.0199	Spink1/Stc1/Cxcl12/Agtr1a/Dysf/Fyn/Pkd2	7
GO:0072676	lymphocyte migration	BP	0.102	0.0062	0.0295	1.53	0.02	Itga4/Cyp7b1/Itgb7/Icam1/Cxcr3/Cxcl12/Msn/Itgal/Il27ra/Cd200/Xcl1	11
GO:0046942	carboxylic acid transport	BP	0.0761	0.00623	0.0296	1.53	0.0201	Slc1a3/Grik1/Pla2g10/Slc13a5/Abat/Drd4/Slc7a2/Grin2b/Abcg2/Slc36a4/Lrp2/Htr1b/Slc6a15/Bdkrb2/Slc23a2/Sfxn5/Nfkbie/Slc38a1/Abcc5/Gabbr1/Cacna1a/Cacnb4	22
GO:1902806	regulation of cell cycle G1/S phase transition	BP	0.0877	0.00638	0.0302	1.52	0.0206	Gli1/Myo16/Tbx2/Ddr2/Tert/Ccnd2/Adamts1/Plcb1/Stxbp4/Pkd1/Fhl1/Pkd2/Atp2b4/Dact1/Cacnb4	15
GO:0032232	negative regulation of actin filament bundle assembly	BP	0.15	0.00644	0.0304	1.52	0.0207	Kank4/Phldb2/Arhgap6/Tmeff2/Arhgap28/Dlc1	6
GO:0060219	camera-type eye photoreceptor cell differentiation	BP	0.15	0.00644	0.0304	1.52	0.0207	Ihh/Sdk2/Thy1/Rp1/Rorb/Ptn	6
GO:0060351	cartilage development involved in endochondral bone morphogenesis	BP	0.15	0.00644	0.0304	1.52	0.0207	Ihh/Hoxd11/Thbs3/Cbs/Hoxa11/Stc1	6
GO:1902624	positive regulation of neutrophil migration	BP	0.15	0.00644	0.0304	1.52	0.0207	Mdk/Ednra/Xcl1/Nckap1l/Dysf/Ptger3	6
GO:2000516	positive regulation of CD4-positive, alpha-beta T cell activation	BP	0.15	0.00644	0.0304	1.52	0.0207	Cd83/Xcl1/Nckap1l/Gimap5/Gimap3/Il2rg	6
GO:0046620	regulation of organ growth	BP	0.0968	0.00655	0.0308	1.51	0.021	Gli1/Cacna1c/Col14a1/Nog/Igf1/Tbx2/Acacb/Mef2c/Flvcr1/Igf2/Pi16/Lats2	12
GO:0021954	central nervous system neuron development	BP	0.106	0.00656	0.0308	1.51	0.021	Map2/Dcc/Zeb2/Nrp1/Tsku/Cdh11/Ndnf/Dclk2/Lhx6/Nin	10
GO:0032273	positive regulation of protein polymerization	BP	0.106	0.00656	0.0308	1.51	0.021	Evl/Pfn2/Icam1/Nckap1l/Slain1/Nin/Bin1/Cdc42ep5/Cav1/Tppp	10
GO:0042475	odontogenesis of dentin-containing tooth	BP	0.106	0.00656	0.0308	1.51	0.021	Wnt6/Lef1/Apcdd1/Fst/Edaradd/Slc24a4/Gli3/Jag2/Tnfrsf11b/Edar	10
GO:0048644	muscle organ morphogenesis	BP	0.106	0.00656	0.0308	1.51	0.021	Col11a1/Angpt1/Nog/Lrp2/Ccm2l/Ednra/Myl3/Heg1/Fzd2/Efemp2	10
GO:0045776	negative regulation of blood pressure	BP	0.121	0.00667	0.0313	1.5	0.0213	Kdr/Adra1a/Abat/Nos3/Calca/Vegfc/Bdkrb2/Apln	8
GO:0090311	regulation of protein deacetylation	BP	0.121	0.00667	0.0313	1.5	0.0213	Lrrk2/Prkd1/Tcf21/Ndn/Aplnr/Dysf/Tada2a/Tppp	8
GO:0097696	receptor signaling pathway via STAT	BP	0.0829	0.00671	0.0315	1.5	0.0214	Stra6/Cyp1b1/Agap2/Ptprd/Igf1/Hcls1/Dab1/Kit/Agtr1a/Pecam1/Pkd1/Csf2rb/Fyn/Pkd2/Stat5b/Il12rb1/Cav1	17
GO:0046661	male sex differentiation	BP	0.0872	0.00672	0.0315	1.5	0.0214	Tex15/Sfrp2/Ar/Kdr/Hoxa11/Hoxa10/Icam1/Tcf21/Lrp2/Tbx3/Hoxa9/Rhobtb3/Smad9/Stat5b/Abcb1a	15
GO:0030850	prostate gland development	BP	0.132	0.00684	0.0319	1.5	0.0217	Ar/Nog/Cyp7b1/Igf1/Cd44/Mmp2/Id4	7
GO:0060412	ventricular septum morphogenesis	BP	0.132	0.00684	0.0319	1.5	0.0217	Wnt11/Nog/Nos3/Aplnr/Tbx3/Heyl/Fzd2	7
GO:0072091	regulation of stem cell proliferation	BP	0.132	0.00684	0.0319	1.5	0.0217	Fermt2/Tert/Vegfc/Tbx3/Kitl/Ltbp3/Septin4	7
GO:0033198	response to ATP	BP	0.172	0.00694	0.0323	1.49	0.022	Ryr1/Slc8a1/P2rx2/Enpp1/Asph	5
GO:0090023	positive regulation of neutrophil chemotaxis	BP	0.172	0.00694	0.0323	1.49	0.022	Mdk/Ednra/Xcl1/Nckap1l/Dysf	5
GO:1904861	excitatory synapse assembly	BP	0.172	0.00694	0.0323	1.49	0.022	Ptprd/Nlgn1/Lrrc4b/Nptx1/Slitrk3	5
GO:0033077	T cell differentiation in thymus	BP	0.105	0.00706	0.0328	1.48	0.0223	Ihh/Cd3g/Gli3/Dock2/Zeb1/Cd1d1/Jag2/Stat5b/Zap70/Il2rg	10
GO:0061053	somite development	BP	0.105	0.00706	0.0328	1.48	0.0223	Ihh/Sfrp2/Lef1/Wnt11/Nog/Zeb2/Foxf1/Lfng/Loxl3/Ptch1	10
GO:0009855	determination of bilateral symmetry	BP	0.0922	0.00714	0.0331	1.48	0.0225	Ihh/Tbx2/Foxf1/Mef2c/Dnah5/Ift57/Aplnr/Tbx3/Dync2h1/Daam2/Pcsk5/Pkd2/Dync2li1	13
GO:0051224	negative regulation of protein transport	BP	0.0922	0.00714	0.0331	1.48	0.0225	Angpt1/Pkdcc/Drd4/Lrrk2/Pkia/Ppm1f/Apoe/Cd200/Neo1/Ptger3/Frmd4a/Rab23/Nr1h3	13
GO:0035850	epithelial cell differentiation involved in kidney development	BP	0.146	0.00728	0.0333	1.48	0.0226	Ptpro/Ednrb/Mef2c/Ednra/Osr1/Fat4	6
GO:0035886	vascular associated smooth muscle cell differentiation	BP	0.146	0.00728	0.0333	1.48	0.0226	Kit/Cth/Aplnr/Ednra/Efemp2/Sgcb	6
GO:0071604	transforming growth factor beta production	BP	0.146	0.00728	0.0333	1.48	0.0226	Wnt11/Fn1/Tsku/Cd200/Ltbp3/Nrros	6
GO:0001707	mesoderm formation	BP	0.119	0.0073	0.0333	1.48	0.0226	Sfrp2/Lef1/Wnt11/Nog/Hoxa11/Foxf1/Snai1/Tal1	8
GO:0030193	regulation of blood coagulation	BP	0.119	0.0073	0.0333	1.48	0.0226	Tfpi/Abat/Serpine2/Apoe/Pros1/Ptger3/St3gal4/Cav1	8
GO:0042461	photoreceptor cell development	BP	0.119	0.0073	0.0333	1.48	0.0226	Thy1/Prdm1/Rp1/Rorb/Arl3/Ttc26/Nphp1/Bbs1	8
GO:0090398	cellular senescence	BP	0.119	0.0073	0.0333	1.48	0.0226	Tbx2/Tert/Abi3/Vash1/Tbx3/Akt3/Smc5/Cav1	8
GO:1902305	regulation of sodium ion transmembrane transport	BP	0.119	0.0073	0.0333	1.48	0.0226	Hecw2/Scn4b/Drd4/Fxyd5/Plcb1/Osr1/Atp2b4/Atp1a2	8
GO:0002315	marginal zone B cell differentiation	BP	0.3	0.00731	0.0333	1.48	0.0226	Dock10/Lfng/Mfng	3
GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	BP	0.3	0.00731	0.0333	1.48	0.0226	Gimap5/Gimap3/Il2rg	3
GO:0002692	negative regulation of cellular extravasation	BP	0.3	0.00731	0.0333	1.48	0.0226	Cxcl12/Plcb1/Il27ra	3
GO:0021957	corticospinal tract morphogenesis	BP	0.3	0.00731	0.0333	1.48	0.0226	Zeb2/Cdh11/Nin	3
GO:0035864	response to potassium ion	BP	0.3	0.00731	0.0333	1.48	0.0226	Nptx1/Dlg2/Dlg4	3
GO:0035865	cellular response to potassium ion	BP	0.3	0.00731	0.0333	1.48	0.0226	Nptx1/Dlg2/Dlg4	3
GO:0043201	response to leucine	BP	0.3	0.00731	0.0333	1.48	0.0226	Klhl22/Rragd/Ubr1	3
GO:0070294	renal sodium ion absorption	BP	0.3	0.00731	0.0333	1.48	0.0226	Ednrb/Maged2/Ednra	3
GO:0071233	cellular response to leucine	BP	0.3	0.00731	0.0333	1.48	0.0226	Klhl22/Rragd/Ubr1	3
GO:0072203	cell proliferation involved in metanephros development	BP	0.3	0.00731	0.0333	1.48	0.0226	Gpc3/Ptch1/Osr1	3
GO:0086064	cell communication by electrical coupling involved in cardiac conduction	BP	0.3	0.00731	0.0333	1.48	0.0226	Slc8a1/Gjc1/Cav1	3
GO:0090269	fibroblast growth factor production	BP	0.3	0.00731	0.0333	1.48	0.0226	Wnt11/Ccm2l/Heg1	3
GO:0090270	regulation of fibroblast growth factor production	BP	0.3	0.00731	0.0333	1.48	0.0226	Wnt11/Ccm2l/Heg1	3
GO:0097105	presynaptic membrane assembly	BP	0.3	0.00731	0.0333	1.48	0.0226	Ptprd/Nlgn1/Nlgn3	3
GO:1900119	positive regulation of execution phase of apoptosis	BP	0.3	0.00731	0.0333	1.48	0.0226	Bok/Cxcr3/Dlc1	3
GO:1902746	regulation of lens fiber cell differentiation	BP	0.3	0.00731	0.0333	1.48	0.0226	Zeb2/Cdkn1c/Spred3	3
GO:0002688	regulation of leukocyte chemotaxis	BP	0.0952	0.00742	0.0336	1.47	0.0229	Mdk/Cxcl12/Jam3/Edn3/Vegfc/Ednra/Xcl1/Nckap1l/Tnfaip6/Dysf/Mpp1/Ptn	12
GO:0009308	amine metabolic process	BP	0.0952	0.00742	0.0336	1.47	0.0229	Maob/Abat/Drd4/Myo5a/Pde1b/Maoa/Hdc/Agtr1a/Ednra/Atp2b4/Slc7a7/Sult1a1	12
GO:0018958	phenol-containing compound metabolic process	BP	0.0952	0.00742	0.0336	1.47	0.0229	Maob/Zeb2/Abat/Drd4/Myo5a/Pde1b/Maoa/Fah/Hdc/Agtr1a/Ednra/Sult1a1	12
GO:0002827	positive regulation of T-helper 1 type immune response	BP	0.211	0.00751	0.0336	1.47	0.0229	Il27ra/H2-Ab1/Xcl1/Il12rb1	4
GO:0003214	cardiac left ventricle morphogenesis	BP	0.211	0.00751	0.0336	1.47	0.0229	Sfrp2/Foxf1/Cpe/Ednra	4
GO:0010544	negative regulation of platelet activation	BP	0.211	0.00751	0.0336	1.47	0.0229	Abat/Serpine2/Apoe/Ptger3	4
GO:0022038	corpus callosum development	BP	0.211	0.00751	0.0336	1.47	0.0229	Zeb2/Tsku/Rtn4rl1/Nin	4
GO:0030011	maintenance of cell polarity	BP	0.211	0.00751	0.0336	1.47	0.0229	Wnt11/Lin7a/Nckap1l/Dlg5	4
GO:0033604	negative regulation of catecholamine secretion	BP	0.211	0.00751	0.0336	1.47	0.0229	Abat/Myo5a/Ptger3/Gabbr1	4
GO:0033623	regulation of integrin activation	BP	0.211	0.00751	0.0336	1.47	0.0229	Fermt2/Jam3/Rasip1/Pcsk5	4
GO:0034111	negative regulation of homotypic cell-cell adhesion	BP	0.211	0.00751	0.0336	1.47	0.0229	Abat/Serpine2/Ccm2l/Ptger3	4
GO:0035461	vitamin transmembrane transport	BP	0.211	0.00751	0.0336	1.47	0.0229	Stra6/Lrp2/Slc23a2/Abcc5	4
GO:0035641	locomotory exploration behavior	BP	0.211	0.00751	0.0336	1.47	0.0229	Lrrk2/Apoe/Dlg4/Atp1a2	4
GO:0045198	establishment of epithelial cell apical/basal polarity	BP	0.211	0.00751	0.0336	1.47	0.0229	Foxf1/Msn/Myo9a/Sh3bp1	4
GO:0045579	positive regulation of B cell differentiation	BP	0.211	0.00751	0.0336	1.47	0.0229	Prdm1/Nckap1l/Stat5b/Il2rg	4
GO:0071514	genomic imprinting	BP	0.211	0.00751	0.0336	1.47	0.0229	H19/Tet1/Ndn/Cdkn1c	4
GO:1905874	regulation of postsynaptic density organization	BP	0.211	0.00751	0.0336	1.47	0.0229	Ptprd/Cdh2/Lrrc4b/Nptx1	4
GO:0009799	specification of symmetry	BP	0.0915	0.00756	0.0338	1.47	0.023	Ihh/Tbx2/Foxf1/Mef2c/Dnah5/Ift57/Aplnr/Tbx3/Dync2h1/Daam2/Pcsk5/Pkd2/Dync2li1	13
GO:0010883	regulation of lipid storage	BP	0.13	0.00757	0.0338	1.47	0.023	Apob/Pla2g10/Acacb/Vstm2a/Mest/Abcg1/Nr1h3	7
GO:0031103	axon regeneration	BP	0.13	0.00757	0.0338	1.47	0.023	Gap43/Mmp2/Enpp1/Rtn4rl1/Neo1/Xylt1/Ptn	7
GO:0032892	positive regulation of organic acid transport	BP	0.13	0.00757	0.0338	1.47	0.023	Acsl6/Grik1/Pla2g10/Abat/Grin2b/Acsl1/Gabbr1	7
GO:0099054	presynapse assembly	BP	0.13	0.00757	0.0338	1.47	0.023	Gpc6/Ptprd/Nlgn1/Lrrc4b/Slitrk3/Nlgn3/Pcdh17	7
GO:0031110	regulation of microtubule polymerization or depolymerization	BP	0.104	0.00759	0.0338	1.47	0.023	Map2/Cdh5/Rp1/Tubb4a/Slain1/Nin/Dysf/Ttbk2/Mapre2/Cav1	10
GO:0044344	cellular response to fibroblast growth factor stimulus	BP	0.104	0.00759	0.0338	1.47	0.023	Hhip/Nog/Tbx2/Cd44/Enpp1/Ndnf/Ccn2/Apln/Fat4/Kif16b	10
GO:0043491	protein kinase B signaling	BP	0.0817	0.00772	0.0344	1.46	0.0234	Sema5a/Angpt1/Kdr/Igf1/Hcls1/Fermt2/Inpp4b/Tek/Cxcl12/Lrp2/Nox4/Magi2/Igf2/Cavin3/Rcn3/Rasd2/Arrb2	17
GO:0030183	B cell differentiation	BP	0.0857	0.00784	0.0349	1.46	0.0237	Itm2a/Flt3/Tnfsf13b/Dock10/Prdm1/Lfng/Kit/H2-Ab1/Enpp1/Irf8/Nckap1l/Hdac9/Stat5b/Mfng/Il2rg	15
GO:0070830	bicellular tight junction assembly	BP	0.11	0.00792	0.0352	1.45	0.0239	Wnt11/Cldn8/Cdh5/Esam/Pecam1/Snai1/Cldn5/Nphp1/Cldn1	9
GO:0097530	granulocyte migration	BP	0.0881	0.00797	0.0354	1.45	0.0241	Cxcl15/Mdk/Jam3/Edn3/Itga1/Ednra/Pecam1/Xcl1/Nckap1l/Tnfaip6/Dysf/Irak4/Ptger3/Mpp1	14
GO:0001963	synaptic transmission, dopaminergic	BP	0.167	0.00804	0.0355	1.45	0.0242	Slc6a2/Aph1b/Drd4/Rasd2/Arrb2	5
GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	BP	0.167	0.00804	0.0355	1.45	0.0242	Angpt1/Kdr/Tek/Vegfc/Emilin1	5
GO:0048596	embryonic camera-type eye morphogenesis	BP	0.167	0.00804	0.0355	1.45	0.0242	Stra6/Ihh/Tbx2/Zeb1/Hipk2	5
GO:0060343	trabecula formation	BP	0.167	0.00804	0.0355	1.45	0.0242	Thbs3/Mmp2/Tek/Adamts1/Enpp1	5
GO:0001843	neural tube closure	BP	0.0982	0.00811	0.0358	1.45	0.0244	Sfrp2/Nog/Zeb2/Lrp2/Ift57/Cecr2/Prickle1/Ptch1/Dlc1/Fzd2/Rab23	11
GO:0018149	peptide cross-linking	BP	0.143	0.00819	0.0361	1.44	0.0246	Spock2/Fn1/Egflam/Mamdc2/Ndnf/Bgn	6
GO:0045066	regulatory T cell differentiation	BP	0.143	0.00819	0.0361	1.44	0.0246	Mdk/Cd44/Sox12/Gimap5/Gimap3/Il2rg	6
GO:0099174	regulation of presynapse organization	BP	0.143	0.00819	0.0361	1.44	0.0246	Gpc6/Ptprd/Nlgn1/Lrrc4b/Slitrk3/Nlgn3	6
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	BP	0.127	0.00837	0.0367	1.44	0.025	Adra1a/Nos3/Ednrb/Enpep/Edn3/Rps6ka2/Agtr1a	7
GO:0010712	regulation of collagen metabolic process	BP	0.127	0.00837	0.0367	1.44	0.025	Ihh/Ddr2/Fn1/Emilin1/Arrb2/Ccn2/Cygb	7
GO:0034113	heterotypic cell-cell adhesion	BP	0.127	0.00837	0.0367	1.44	0.025	Itga4/Cd44/Itgb7/Jam3/Thy1/Cd200/Itga7	7
GO:0046580	negative regulation of Ras protein signal transduction	BP	0.127	0.00837	0.0367	1.44	0.025	Adra1a/Rasa3/Rasip1/Arap3/Heg1/Dlc1/Syngap1	7
GO:0055010	ventricular cardiac muscle tissue morphogenesis	BP	0.127	0.00837	0.0367	1.44	0.025	Col11a1/Nog/Lrp2/Ccm2l/Ednra/Myl3/Heg1	7
GO:2001222	regulation of neuron migration	BP	0.127	0.00837	0.0367	1.44	0.025	Ptprz1/Mdk/Tbc1d24/Gpr173/Neo1/Sema6a/Ntng1	7
GO:0031109	microtubule polymerization or depolymerization	BP	0.0938	0.00838	0.0367	1.44	0.025	Map2/Cdh5/Rp1/Tubb4a/Slain1/Nin/Dysf/Ttbk2/Mapre2/Cav1/Tppp/Map7d3	12
GO:0033673	negative regulation of kinase activity	BP	0.0793	0.00844	0.0369	1.43	0.0251	Sfrp2/Ddr2/Ptpro/Slc8a1/Mapk8ip1/Slc8a3/Pkia/Thy1/Ppm1f/Cdkn1c/Apoe/Rasip1/Ppm1e/Pkib/Heg1/Lats2/Smpd1/Cav1	18
GO:0060606	tube closure	BP	0.0973	0.00865	0.0378	1.42	0.0257	Sfrp2/Nog/Zeb2/Lrp2/Ift57/Cecr2/Prickle1/Ptch1/Dlc1/Fzd2/Rab23	11
GO:0071774	response to fibroblast growth factor	BP	0.102	0.00874	0.0381	1.42	0.026	Hhip/Nog/Tbx2/Cd44/Enpp1/Ndnf/Ccn2/Apln/Fat4/Kif16b	10
GO:0007018	microtubule-based movement	BP	0.0681	0.0089	0.0388	1.41	0.0264	Apob/Map2/Fez1/Tub/Kif7/Myo5a/Wdr35/Adcy3/Cacna1e/Dnah5/Ift57/Pltp/Kif1a/Dlg2/Kif6/Dync2h1/Arl3/Ttc26/Dzip1/Sord/Septin4/Dnah7b/Atp2b4/Stard9/Dnah1/Dync2li1/Nsun7/Bbs1/Kif16b	29
GO:0062012	regulation of small molecule metabolic process	BP	0.0701	0.00901	0.0393	1.41	0.0267	Apob/Igf1/Nos3/Acacb/Pth1r/Dkk3/Kit/Apoe/Enpp1/Kcnma1/Igf2/Snai1/Lacc1/Adcyap1r1/Htr2a/Zbtb20/Abcg1/Abcd2/Atp2b4/Fam3c/Slc7a7/Cav1/Nr1h3/Cacna1a/Pid1/Igfbp4	26
GO:0010766	negative regulation of sodium ion transport	BP	0.2	0.00908	0.0394	1.4	0.0268	Hecw2/Serpine2/Osr1/Atp1a2	4
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	BP	0.2	0.00908	0.0394	1.4	0.0268	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0032252	secretory granule localization	BP	0.2	0.00908	0.0394	1.4	0.0268	Map2/Myo5a/Ppfia2/Kif1a	4
GO:0045986	negative regulation of smooth muscle contraction	BP	0.2	0.00908	0.0394	1.4	0.0268	Calca/Gucy1a1/Kcnma1/Calcrl	4
GO:0048557	embryonic digestive tract morphogenesis	BP	0.2	0.00908	0.0394	1.4	0.0268	Ihh/Foxf1/Gli3/Tcf21	4
GO:1902430	negative regulation of amyloid-beta formation	BP	0.2	0.00908	0.0394	1.4	0.0268	Igf1/Rtn1/Apoe/Bin1	4
GO:0030902	hindbrain development	BP	0.0843	0.0091	0.0395	1.4	0.0269	Gli1/Lef1/Mdk/Nog/Igf1/Cbs/Dab1/B4galt2/Serpine2/Zfp423/Cplane1/Smad9/Ttbk2/Dlc1/Cacna1a	15
GO:0034331	cell junction maintenance	BP	0.14	0.00919	0.0397	1.4	0.027	Epb41l3/Fermt2/Shank2/Erc2/Syngap1/Cldn1	6
GO:0048873	homeostasis of number of cells within a tissue	BP	0.14	0.00919	0.0397	1.4	0.027	Tex15/Col14a1/Nos3/Flt3/Coro1a/Akt3	6
GO:0051281	positive regulation of release of sequestered calcium ion into cytosol	BP	0.14	0.00919	0.0397	1.4	0.027	Cxcr3/Thy1/Aplnr/Ednra/Pkd2/Gstm7	6
GO:0001974	blood vessel remodeling	BP	0.125	0.00922	0.0397	1.4	0.027	Itga4/Igf1/Nos3/Cbs/Mef2c/Erg/Ednra	7
GO:2000649	regulation of sodium ion transmembrane transporter activity	BP	0.125	0.00922	0.0397	1.4	0.027	Hecw2/Scn4b/Drd4/Fxyd5/Plcb1/Osr1/Atp1a2	7
GO:0032272	negative regulation of protein polymerization	BP	0.107	0.00923	0.0397	1.4	0.027	Kank4/Map2/Evl/Tmod2/Pfn2/Cdh5/Tubb4a/Pecam1/Scin	9
GO:0009743	response to carbohydrate	BP	0.0802	0.00925	0.0397	1.4	0.027	Apob/Igf1/P2rx2/Ano1/Icam1/Cacna1e/Plcb1/Rps6ka2/Stxbp4/Rab34/Nox4/Enpp1/Arrb1/Sarm1/Zbtb20/Abcg1/Calcrl	17
GO:0010453	regulation of cell fate commitment	BP	0.161	0.00926	0.0397	1.4	0.027	Sfrp2/Ar/Wnt11/Glis1/Loxl3	5
GO:0021952	central nervous system projection neuron axonogenesis	BP	0.161	0.00926	0.0397	1.4	0.027	Dcc/Zeb2/Tsku/Cdh11/Nin	5
GO:0033137	negative regulation of peptidyl-serine phosphorylation	BP	0.161	0.00926	0.0397	1.4	0.027	Hgf/Ppm1f/Bdkrb2/Rassf2/Cav1	5
GO:0061036	positive regulation of cartilage development	BP	0.161	0.00926	0.0397	1.4	0.027	Mdk/Hoxd11/Pkdcc/Hoxa11/Gli3	5
GO:0071624	positive regulation of granulocyte chemotaxis	BP	0.161	0.00926	0.0397	1.4	0.027	Mdk/Ednra/Xcl1/Nckap1l/Dysf	5
GO:0043299	leukocyte degranulation	BP	0.101	0.00936	0.0401	1.4	0.0273	Foxf1/Coro1a/Kit/Nckap1l/Myo1f/Cd84/Fgr/Lat/Rab27a/Clnk	10
GO:0033138	positive regulation of peptidyl-serine phosphorylation	BP	0.0923	0.00943	0.0404	1.39	0.0275	Sfrp2/Angpt1/Cd44/Hcls1/Pfn2/Prkd1/Tek/Caprin2/Arrb1/Arrb2/Atp2b4/Cav1	12
GO:0062197	cellular response to chemical stress	BP	0.0714	0.00945	0.0404	1.39	0.0275	Cyp1b1/Hgf/Ddr2/Nos3/Slc8a1/Lrrk2/Mmp2/Prkd1/Tbc1d24/Trpc6/Scn2a/Prr5l/Ednra/Aifm2/Bdkrb2/Dysf/Selenon/Net1/Mgat3/Fyn/Pkd2/Slc25a23/Cav1/Stx2	24
GO:0042246	tissue regeneration	BP	0.114	0.00946	0.0404	1.39	0.0275	Gap43/Mdk/Igf1/Hopx/Dysf/Selenon/Ptn/Large1	8
GO:0050885	neuromuscular process controlling balance	BP	0.114	0.00946	0.0404	1.39	0.0275	Ankfn1/Slc1a3/Jph4/Myo5a/Kcnma1/Foxs1/Dlg4/Cacna1a	8
GO:2000514	regulation of CD4-positive, alpha-beta T cell activation	BP	0.114	0.00946	0.0404	1.39	0.0275	Cd83/Cd44/Loxl3/Xcl1/Nckap1l/Gimap5/Gimap3/Il2rg	8
GO:0002318	myeloid progenitor cell differentiation	BP	0.273	0.00974	0.0409	1.39	0.0278	Jam3/Flt3/Kit	3
GO:0003139	secondary heart field specification	BP	0.273	0.00974	0.0409	1.39	0.0278	Wnt11/Mef2c/Lrp2	3
GO:0006171	cAMP biosynthetic process	BP	0.273	0.00974	0.0409	1.39	0.0278	Adcy3/Adcy4/Adcy7	3
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	BP	0.273	0.00974	0.0409	1.39	0.0278	Gli1/Igf1/Zfp423	3
GO:0030202	heparin metabolic process	BP	0.273	0.00974	0.0409	1.39	0.0278	Angpt1/Ednrb/Ednra	3
GO:0032815	negative regulation of natural killer cell activation	BP	0.273	0.00974	0.0409	1.39	0.0278	Havcr2/Fgr/Clnk	3
GO:0034454	microtubule anchoring at centrosome	BP	0.273	0.00974	0.0409	1.39	0.0278	Ninl/Nin/Cep19	3
GO:0035701	hematopoietic stem cell migration	BP	0.273	0.00974	0.0409	1.39	0.0278	Jam3/Kit/Enpp1	3
GO:0036302	atrioventricular canal development	BP	0.273	0.00974	0.0409	1.39	0.0278	Tbx2/Has2/Tbx3	3
GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway	BP	0.273	0.00974	0.0409	1.39	0.0278	Ar/Igf1/Igfbp4	3
GO:0060405	regulation of penile erection	BP	0.273	0.00974	0.0409	1.39	0.0278	Ar/Drd4/Ednrb	3
GO:0060600	dichotomous subdivision of an epithelial terminal unit	BP	0.273	0.00974	0.0409	1.39	0.0278	Nrp1/Areg/Plxnd1	3
GO:0071372	cellular response to follicle-stimulating hormone stimulus	BP	0.273	0.00974	0.0409	1.39	0.0278	Epha8/Epha3/Ednra	3
GO:0072178	nephric duct morphogenesis	BP	0.273	0.00974	0.0409	1.39	0.0278	Gpc3/Epha7/Osr1	3
GO:0086016	AV node cell action potential	BP	0.273	0.00974	0.0409	1.39	0.0278	Cacna1c/Scn4b/Ank2	3
GO:0086027	AV node cell to bundle of His cell signaling	BP	0.273	0.00974	0.0409	1.39	0.0278	Cacna1c/Scn4b/Ank2	3
GO:0099545	trans-synaptic signaling by trans-synaptic complex	BP	0.273	0.00974	0.0409	1.39	0.0278	Efnb3/Ptprd/Nlgn1	3
GO:1902946	protein localization to early endosome	BP	0.273	0.00974	0.0409	1.39	0.0278	Nrp1/Msn/Mgat3	3
GO:1903564	regulation of protein localization to cilium	BP	0.273	0.00974	0.0409	1.39	0.0278	Ccdc88a/Crocc/Dzip1	3
GO:2000344	positive regulation of acrosome reaction	BP	0.273	0.00974	0.0409	1.39	0.0278	Pla2g10/Plcb1/Cacna1h	3
GO:0051259	protein complex oligomerization	BP	0.0766	0.00985	0.0413	1.38	0.0281	Kcnb2/Kcna6/Kcnd2/Kcnd3/Evl/Acacb/Bok/Grin2b/Ikzf4/Cth/Kcnc4/Pkd1/Mpp2/Nlrp1b/Aqp11/Kcng4/Pkd2/Steap4/Cldn1	19
GO:0010469	regulation of signaling receptor activity	BP	0.0884	0.00998	0.0418	1.38	0.0285	Begain/Nog/Nlgn1/Areg/Slc24a4/Nptx1/Mef2c/Cnrip1/Nlgn3/Nptxr/Prrt1/Cacng7/Dlg4	13
GO:0051592	response to calcium ion	BP	0.0916	0.00999	0.0419	1.38	0.0285	Nlgn1/Syt13/Cpne5/Mef2c/Rasgrp2/Syt7/Kcnma1/Asph/Pkd2/Slc25a23/Smpd1/Cav1	12
GO:0007254	JNK cascade	BP	0.0833	0.01	0.042	1.38	0.0286	Sfrp2/Eda2r/Lrrk2/Mapk8ip1/Plcb1/Cracr2a/Grik2/Hipk2/Rassf2/Mapkbp1/Irak4/Ccn2/Cdc42ep5/Dact1/Edar	15
GO:0008361	regulation of cell size	BP	0.0794	0.0101	0.0423	1.37	0.0288	Map2/Sema5a/Sema5b/Slc12a8/Sema7a/Nrp1/Fn1/Cxcl12/Apoe/Kcnma1/Sema3g/Epha7/Aqp11/Slc12a4/Akt3/Sema6a/C1qtnf9	17
GO:0030514	negative regulation of BMP signaling pathway	BP	0.123	0.0101	0.0424	1.37	0.0288	Sfrp2/Nog/Lrp2/Tnfaip6/Hipk2/Cav1/Tmprss6	7
GO:0008207	C21-steroid hormone metabolic process	BP	0.136	0.0103	0.0428	1.37	0.0291	Ednrb/Dkk3/Kcnma1/Cyp46a1/Cacna1h/Stat5b	6
GO:0010464	regulation of mesenchymal cell proliferation	BP	0.136	0.0103	0.0428	1.37	0.0291	Ihh/Wnt11/Kdr/Foxf1/Zeb1/Ptn	6
GO:0046640	regulation of alpha-beta T cell proliferation	BP	0.136	0.0103	0.0428	1.37	0.0291	Cd44/Mapk8ip1/Btla/Xcl1/Zap70/Il12rb1	6
GO:0007193	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway	BP	0.113	0.0103	0.0428	1.37	0.0291	Drd4/Npr3/Akap12/Htr1b/Ednra/Gnaz/Palm/Gabbr1	8
GO:0035710	CD4-positive, alpha-beta T cell activation	BP	0.0948	0.0104	0.0435	1.36	0.0296	Lef1/Cd83/Cd44/Loxl3/Cracr2a/Xcl1/Nckap1l/Satb1/Gimap5/Gimap3/Il2rg	11
GO:0043244	regulation of protein-containing complex disassembly	BP	0.0909	0.0106	0.0439	1.36	0.0298	Map2/Sema5a/Evl/Tmod2/Rp1/Sh3bp1/Scin/Dysf/Asph/Ttbk2/Nes/Plekhh2	12
GO:0030705	cytoskeleton-dependent intracellular transport	BP	0.0808	0.0106	0.0439	1.36	0.0298	Map2/Fez1/Tub/Ccdc88a/Myo5a/Wdr35/Ppfia2/Ift57/Kif1a/Dlg2/Dync2h1/Arl3/Ttc26/Myo1f/Dync2li1/Bbs1	16
GO:0002825	regulation of T-helper 1 type immune response	BP	0.156	0.0106	0.0439	1.36	0.0298	Il27ra/H2-Ab1/Havcr2/Xcl1/Il12rb1	5
GO:0003416	endochondral bone growth	BP	0.156	0.0106	0.0439	1.36	0.0298	Kdr/Ddr2/Evc/Thbs3/Stc1	5
GO:0010259	multicellular organism aging	BP	0.156	0.0106	0.0439	1.36	0.0298	Rnf165/Adra1a/Enpp1/Agtr1a/Ednra	5
GO:0030511	positive regulation of transforming growth factor beta receptor signaling pathway	BP	0.156	0.0106	0.0439	1.36	0.0298	Zeb2/Npnt/Cdkn1c/Hipk2/Itga8	5
GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	BP	0.156	0.0106	0.0439	1.36	0.0298	Cd83/Nckap1l/Gimap5/Gimap3/Il2rg	5
GO:1903846	positive regulation of cellular response to transforming growth factor beta stimulus	BP	0.156	0.0106	0.0439	1.36	0.0298	Zeb2/Npnt/Cdkn1c/Hipk2/Itga8	5
GO:0046785	microtubule polymerization	BP	0.105	0.0107	0.0442	1.35	0.0301	Map2/Cdh5/Rp1/Tubb4a/Slain1/Nin/Cav1/Tppp/Map7d3	9
GO:0002274	myeloid leukocyte activation	BP	0.0746	0.0108	0.0446	1.35	0.0304	Pla2g10/Fn1/Lrrk2/Foxf1/Slc7a2/Dock2/Cd1d1/Kit/Cd226/Havcr2/Cd200/Dysf/Myo1f/Cd84/Fgr/Gimap5/Gimap3/Lat/Clnk/Nr1h3	20
GO:0001946	lymphangiogenesis	BP	0.19	0.0108	0.0446	1.35	0.0304	Vash1/Vegfc/Tie1/Pkd1	4
GO:0032332	positive regulation of chondrocyte differentiation	BP	0.19	0.0108	0.0446	1.35	0.0304	Hoxd11/Pkdcc/Hoxa11/Gli3	4
GO:0097107	postsynaptic density assembly	BP	0.19	0.0108	0.0446	1.35	0.0304	Ptprd/Lrrc4b/Nptx1/Slitrk3	4
GO:2000353	positive regulation of endothelial cell apoptotic process	BP	0.19	0.0108	0.0446	1.35	0.0304	Itga4/Cd248/Ecscr/Col18a1	4
GO:0030879	mammary gland development	BP	0.0848	0.0109	0.0447	1.35	0.0304	Ar/Lef1/Agap2/Igf1/Tbx2/Hoxd9/Areg/Foxf1/Gli3/Tbx3/Hoxa9/Ptch1/Stat5b/Cav1	14
GO:0051260	protein homooligomerization	BP	0.0824	0.011	0.0454	1.34	0.0309	Kcnb2/Kcna6/Kcnd2/Kcnd3/Evl/Acacb/Ikzf4/Cth/Kcnc4/Mpp2/Nlrp1b/Aqp11/Kcng4/Pkd2/Steap4	15
GO:0019218	regulation of steroid metabolic process	BP	0.094	0.0111	0.0455	1.34	0.031	Apob/Igf1/Dkk3/Kit/Apoe/Agtr1a/Kcnma1/Igf2/Snai1/Abcg1/Stat5b	11
GO:2001056	positive regulation of cysteine-type endopeptidase activity	BP	0.0872	0.0111	0.0456	1.34	0.031	Bok/Grin2b/Wdr35/Ift57/Ppm1f/Hip1/Arrb1/Asph/Dlc1/Nlrp1b/Ccn2/Fyn/Cyfip2	13
GO:0010633	negative regulation of epithelial cell migration	BP	0.111	0.0111	0.0456	1.34	0.031	Evl/Mef2c/Pfn2/Stc1/Vash1/Ptprm/Apoe/Atp2b4	8
GO:0055008	cardiac muscle tissue morphogenesis	BP	0.111	0.0111	0.0456	1.34	0.031	Col11a1/Angpt1/Nog/Lrp2/Ccm2l/Ednra/Myl3/Heg1	8
GO:0016050	vesicle organization	BP	0.0732	0.0113	0.0463	1.33	0.0315	Syt13/Zeb2/Stx1b/Sec16b/Serpine2/Ap1m1/Rab34/Cadps/Srpx/Coro1a/Syt7/Prrt2/Dysf/Abcg1/Aqp11/Dlg4/Ccdc136/Rab27a/Arfgap3/Stx2/Nkd2	21
GO:0006040	amino sugar metabolic process	BP	0.133	0.0114	0.0466	1.33	0.0317	St6gal2/Npl/Chst2/Chst1/Mgat3/Uap1l1	6
GO:0030225	macrophage differentiation	BP	0.133	0.0114	0.0466	1.33	0.0317	Hcls1/Calca/Plcb1/Enpp1/Zbtb46/Nrros	6
GO:0086009	membrane repolarization	BP	0.133	0.0114	0.0466	1.33	0.0317	Kcnd3/Scn4b/Slc24a4/Cacna2d1/Ank2/Cav1	6
GO:1902991	regulation of amyloid precursor protein catabolic process	BP	0.133	0.0114	0.0466	1.33	0.0317	Igf1/Rtn1/Slc2a13/Apoe/Bin1/Abcg1	6
GO:0045995	regulation of embryonic development	BP	0.103	0.0115	0.0469	1.33	0.0319	Sfrp2/Phldb2/Lama4/Osr2/Plcb1/Tgif2/Lama2/Osr1/Tada2a	9
GO:0043405	regulation of MAP kinase activity	BP	0.08	0.0116	0.0472	1.33	0.0321	Sfrp2/Zeb2/Cbs/Drd4/Lrrk2/Mapk8ip1/Edn3/Pik3r6/Kit/Nox4/Apoe/Htr2a/Kitl/Pde5a/Smpd1/Cav1	16
GO:0060538	skeletal muscle organ development	BP	0.078	0.012	0.0488	1.31	0.0332	Stra6/Hoxd10/Ryr1/P2rx2/Hoxd9/Mef2c/Tcf21/Heyl/Igf2/Hdac9/Dysf/Selenon/Hlf/Large1/Cav1/Zfp689/Usp2	17
GO:0061045	negative regulation of wound healing	BP	0.11	0.0121	0.049	1.31	0.0333	Cd109/Tfpi/Abat/Phldb2/Serpine2/Apoe/Pros1/Ptger3	8
GO:0050999	regulation of nitric-oxide synthase activity	BP	0.152	0.0121	0.049	1.31	0.0333	Npr3/Tert/Apoe/Atp2b4/Cav1	5
GO:1905314	semi-lunar valve development	BP	0.152	0.0121	0.049	1.31	0.0333	Stra6/Nos3/Emilin1/Tie1/Heyl	5
GO:1901605	alpha-amino acid metabolic process	BP	0.0815	0.0121	0.0491	1.31	0.0334	Aspg/Ddah1/Nos3/Cbs/Asrgl1/Gamt/Kyat1/Fah/Amdhd1/Cth/Phgdh/Nox4/Atp2b4/Asl/Slc7a7	15
GO:1903793	positive regulation of anion transport	BP	0.119	0.0122	0.0493	1.31	0.0335	Grik1/Pla2g10/Abat/Tcaf1/Grin2b/Abcb1a/Gabbr1	7
GO:0051147	regulation of muscle cell differentiation	BP	0.0861	0.0123	0.0499	1.3	0.0339	Igf1/Mef2c/Hopx/Tshz3/Zeb1/Kit/Cth/Igf2/Hdac9/Arrb2/Pi16/Rbpms2/Efemp2	13
GO:1900180	regulation of protein localization to nucleus	BP	0.0861	0.0123	0.0499	1.3	0.0339	Angpt1/Hcls1/Fermt2/Tert/Prkd1/Tek/Gli3/Pkia/Dclk2/Fyn/Rab23/Lats2/Cacnb4	13
GO:0051604	protein maturation	BP	0.0698	0.0124	0.05	1.3	0.034	Cpxm2/Ihh/Mmp16/Aph1b/Lrrk2/Serpine2/Gli3/Rps6ka2/Cpe/Mme/C1rl/Ldlrad3/Dync2h1/Pcsk5/C1ra/Ptch1/Asph/Tspan5/Ece2/Adam19/Arxes2/Naa11/Cyfip2/Nkd2	24
GO:0097060	synaptic membrane	CC	0.174	7.95e-23	4.13e-20	19.4	2.76e-20	Ptprz1/Efnb3/Kcnj3/Grid1/Gria4/Grik1/Cacna1c/Lrrc4c/Slc6a2/Kcnd2/Dcc/Ptprd/Kcnd3/Grid2ip/Nlgn1/Ptpro/Rims3/Slc8a1/Stx1b/P2rx2/Nrp1/Cdh2/Lrrc4b/Grin2b/Shank2/Cacna1e/Ank2/Adgrl1/Slitrk3/Col13a1/Htr1b/Cpe/Syde1/Glrb/Gabra4/Dlg2/Scn2a/Nlgn3/Lin7a/Dgkb/Sorcs2/Grik2/Prrt1/Syt7/Kcnma1/Prrt2/Zc4h2/Hip1/Septin3/Nsg1/Arrb1/Epha7/Cacng7/Erc2/Pcdh17/Lrfn2/Mpp2/Cacna1h/Arrb2/Dlg4/Magee1/Palm/Ntng1/Stx2/Gabbr1/Slc4a8/Itga8/Sspn	68
GO:0062023	collagen-containing extracellular matrix	CC	0.159	3.96e-19	1.03e-16	16	6.88e-17	Ndp/Gpc6/Col11a1/Ptprz1/Hmcn1/Vit/Angpt1/Emid1/Col14a1/Colec12/Igf1/Col4a6/Npnt/Thbs3/Lamc3/Spock2/Lama4/Cspg4/Tgfbi/Gpc3/Fn1/Col16a1/Nid1/Serpine2/Egflam/Angptl2/Adamts1/Col9a2/Frem1/Col13a1/Mamdc2/Postn/Smoc1/Loxl3/Mgp/Adamts10/Lama2/Matn2/Sparcl1/Tmeff2/Emilin1/Igf2/Col5a2/Col15a1/Ltbp3/Bgn/Adamtsl1/P3h1/Vwa1/Abi3bp/Dpt/Angptl4/Adam19/Egfl7/Efemp2/Plxdc2/Ptn/Col23a1/Ntng1/Gpc2/Adamts17/Col18a1/Itgb4	63
GO:0045211	postsynaptic membrane	CC	0.176	1.21e-16	2.1e-14	13.7	1.4e-14	Ptprz1/Grid1/Gria4/Grik1/Cacna1c/Lrrc4c/Kcnd2/Dcc/Kcnd3/Grid2ip/Nlgn1/Ptpro/Slc8a1/Nrp1/Cdh2/Lrrc4b/Grin2b/Shank2/Cacna1e/Ank2/Slitrk3/Col13a1/Glrb/Gabra4/Dlg2/Nlgn3/Lin7a/Dgkb/Sorcs2/Grik2/Prrt1/Kcnma1/Prrt2/Zc4h2/Hip1/Nsg1/Arrb1/Epha7/Cacng7/Pcdh17/Lrfn2/Mpp2/Cacna1h/Arrb2/Dlg4/Magee1/Gabbr1/Sspn	48
GO:0098978	glutamatergic synapse	CC	0.158	1.35e-15	1.75e-13	12.8	1.17e-13	Efnb3/Syn2/Grid1/Gria4/Lrrc4c/Begain/Kcnd2/Ptprd/Nlgn1/Ptpro/Drd4/Nrp1/Lrrc4b/Wasf3/Lrrk2/Nptx1/Myo5a/Pfn2/Grin2b/Ppfia2/Plcb1/Cadps/Dlg2/Gucy1a1/Scn2a/Coro1a/Abi2/Dgkb/Nptxr/Grik2/Apoe/Syt7/Prrt2/Sparcl1/Cdh11/Nsg1/Epha7/Cacng7/Erc2/Pcdh17/Mpp2/Cacna1h/Cpt1c/Dlg4/Syngap1/Ngef/Ntng1/Nrn1/Slc4a8/Cacna1a/Cacnb4	51
GO:0098984	neuron to neuron synapse	CC	0.144	3.28e-14	3.41e-12	11.5	2.28e-12	Gap43/Efnb3/Syn2/Map2/Grid1/Gria4/Grik1/Cacna1c/Lrrc4c/Kcnd2/Dcc/Ptprd/Kcnd3/Epb41l3/Lrrc7/Ptpro/Slc8a1/P2rx2/Cdh2/Lrrc4b/Dab1/Grin2b/Shank2/Ank2/Adgrl1/Slc8a3/Slitrk3/Rps6kc1/Dlg2/Nrgn/Sorcs2/Grik2/Prrt1/Cap2/Arrb1/Pdzd2/Cacng7/Ptch1/Erc2/Lrfn2/Cnn3/Mpp2/Arrb2/Fyn/Dlg4/Palm/Dlg5/Syngap1/Arhgef9/Slc4a8/Itga8/Cpeb1	52
GO:0032279	asymmetric synapse	CC	0.147	4.02e-14	3.41e-12	11.5	2.28e-12	Gap43/Syn2/Map2/Grid1/Gria4/Grik1/Cacna1c/Lrrc4c/Kcnd2/Dcc/Kcnd3/Epb41l3/Lrrc7/Ptpro/Slc8a1/P2rx2/Cdh2/Lrrc4b/Dab1/Grin2b/Shank2/Ank2/Adgrl1/Slc8a3/Slitrk3/Rps6kc1/Dlg2/Nrgn/Sorcs2/Grik2/Prrt1/Cap2/Arrb1/Pdzd2/Cacng7/Ptch1/Erc2/Lrfn2/Cnn3/Mpp2/Arrb2/Fyn/Dlg4/Palm/Dlg5/Syngap1/Arhgef9/Slc4a8/Itga8/Cpeb1	50
GO:0099572	postsynaptic specialization	CC	0.145	4.59e-14	3.41e-12	11.5	2.28e-12	Gap43/Syn2/Map2/Grid1/Gria4/Grik1/Cacna1c/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Epb41l3/Lrrc7/Ptpro/Slc8a1/P2rx2/Cdh2/Lrrc4b/Dab1/Grin2b/Shank2/Ank2/Adgrl1/Slc8a3/Slitrk3/Rps6kc1/Dlg2/Nlgn3/Nrgn/Sorcs2/Grik2/Prrt1/Cap2/Arrb1/Pdzd2/Cacng7/Ptch1/Erc2/Lrfn2/Cnn3/Mpp2/Arrb2/Fyn/Dlg4/Palm/Dlg5/Syngap1/Arhgef9/Itga8/Cpeb1	51
GO:0014069	postsynaptic density	CC	0.148	5.57e-14	3.62e-12	11.4	2.42e-12	Gap43/Syn2/Map2/Grid1/Gria4/Grik1/Cacna1c/Lrrc4c/Kcnd2/Dcc/Kcnd3/Epb41l3/Lrrc7/Ptpro/Slc8a1/P2rx2/Cdh2/Lrrc4b/Dab1/Grin2b/Shank2/Ank2/Adgrl1/Slc8a3/Slitrk3/Rps6kc1/Dlg2/Nrgn/Sorcs2/Grik2/Prrt1/Cap2/Arrb1/Pdzd2/Cacng7/Ptch1/Erc2/Lrfn2/Cnn3/Mpp2/Arrb2/Fyn/Dlg4/Palm/Dlg5/Syngap1/Arhgef9/Itga8/Cpeb1	49
GO:0042734	presynaptic membrane	CC	0.212	2.51e-12	1.31e-10	9.88	8.73e-11	Efnb3/Kcnj3/Grik1/Cacna1c/Slc6a2/Ptprd/Rims3/Stx1b/P2rx2/Cdh2/Grin2b/Cacna1e/Adgrl1/Htr1b/Scn2a/Grik2/Syt7/Kcnma1/Prrt2/Hip1/Septin3/Erc2/Pcdh17/Cacna1h/Ntng1/Stx2/Gabbr1/Slc4a8	28
GO:0042383	sarcolemma	CC	0.188	5.06e-12	2.39e-10	9.62	1.6e-10	Kcnj3/Car4/Sgcd/Cacna1c/Kcnd2/Ryr1/Adra1a/Nos3/Slc8a1/Cdh2/Scn1a/Cacna2d1/Ank2/Slc8a3/Msn/Scn2a/Lama2/Ednra/Itga7/Bgn/Bin1/Cacng7/Dysf/Ryr3/Flnc/Cacna1h/Atp2b4/Atp1a2/Sgcb/Cav1/Sspn	31
GO:0034703	cation channel complex	CC	0.161	1.2e-11	5.2e-10	9.28	3.47e-10	Kcnb2/Kcnj3/Gria4/Grik1/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/Scn1a/Kcnq5/Cachd1/Cacna2d1/Grin2b/Cacna1e/Unc80/Trpc6/Scn2a/Grik2/Kcnma1/Kcnc4/Pkd1/Cacng7/Kcnip3/Ryr3/Cacna1h/Cpt1c/Kcng4/Pkd2/Scn3a/Dlg4/Nrn1/Kcnq4/Cacna1a/Cacnb4	36
GO:0098857	membrane microdomain	CC	0.124	4.24e-11	1.47e-09	8.83	9.81e-10	Angpt1/Cacna1c/Kcnd2/Dcc/Kdr/Kcnd3/Tfpi/Nos3/Rgs16/Gnai1/Cdh2/Ednrb/Lrrk2/Ano1/Icam1/Abcg2/Tek/Has2/Adcy3/Cdh13/Tnfrsf22/Gprc5b/Itga1/Lrp2/Cpe/Thy1/Plpp3/Mme/Sele/Kcnma1/Ednra/Pecam1/Adcyap1r1/Rtn4rl1/Cavin3/Dysf/Ptch1/Dlc1/Cacna1h/Cavin2/Fyn/Atp1a2/Zap70/Plpp1/Abcg3/Cav1/Stx2/Gabbr1/Lipe	49
GO:0034702	ion channel complex	CC	0.139	4.78e-11	1.55e-09	8.81	1.04e-09	Kcnb2/Kcnj3/Gria4/Grik1/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/Scn1a/Kcnq5/Cachd1/Cacna2d1/Ano1/Grin2b/Cacna1e/Ano2/Unc80/Ttyh2/Trpc6/Glrb/Gabra4/Scn2a/Grik2/Kcnma1/Kcnc4/Pkd1/Cacng7/Kcnip3/Ryr3/Cacna1h/Cpt1c/Kcng4/Pkd2/Scn3a/Dlg4/Nrn1/Kcnq4/Cacna1a/Cacnb4	41
GO:0099240	intrinsic component of synaptic membrane	CC	0.203	9.85e-11	3.01e-09	8.52	2.01e-09	Efnb3/Kcnj3/Grid1/Lrrc4c/Kcnd2/Dcc/Ptprd/Kcnd3/Nlgn1/Ptpro/Nrp1/Cdh2/Lrrc4b/Grin2b/Cacna1e/Slitrk3/Htr1b/Scn2a/Nlgn3/Prrt2/Pcdh17/Lrfn2/Mpp2/Cacna1h/Ntng1	25
GO:0045121	membrane raft	CC	0.122	1.25e-10	3.63e-09	8.44	2.42e-09	Angpt1/Cacna1c/Kcnd2/Dcc/Kdr/Kcnd3/Tfpi/Nos3/Rgs16/Gnai1/Cdh2/Ednrb/Lrrk2/Ano1/Icam1/Abcg2/Tek/Has2/Adcy3/Cdh13/Tnfrsf22/Gprc5b/Itga1/Lrp2/Cpe/Thy1/Plpp3/Mme/Sele/Kcnma1/Ednra/Pecam1/Adcyap1r1/Rtn4rl1/Cavin3/Ptch1/Dlc1/Cacna1h/Cavin2/Fyn/Atp1a2/Zap70/Plpp1/Abcg3/Cav1/Stx2/Gabbr1/Lipe	48
GO:0099699	integral component of synaptic membrane	CC	0.204	5.32e-10	1.46e-08	7.84	9.73e-09	Efnb3/Kcnj3/Grid1/Lrrc4c/Kcnd2/Dcc/Ptprd/Kcnd3/Nlgn1/Ptpro/Nrp1/Cdh2/Lrrc4b/Grin2b/Cacna1e/Slitrk3/Htr1b/Scn2a/Nlgn3/Prrt2/Pcdh17/Lrfn2/Cacna1h	23
GO:0005604	basement membrane	CC	0.193	1.55e-09	3.67e-08	7.44	2.45e-08	Hmcn1/Col4a6/Npnt/Lamc3/Lama4/Tgfbi/Fn1/Nid1/Egflam/Adamts1/Frem1/Smoc1/Lama2/Matn2/Tmeff2/Col15a1/P3h1/Vwa1/Efemp2/Ptn/Ntng1/Col18a1/Itgb4	23
GO:0016323	basolateral plasma membrane	CC	0.134	9.7e-09	2.19e-07	6.66	1.47e-07	Slc1a3/Slc13a5/Lrrc7/Slc8a1/Cd44/Cdh2/Tek/Cldn8/Ank2/Pth1r/Plpp3/Dlg2/Msn/Slc29a1/Heph/Lin7a/Cd38/Agtr1a/Slc23a2/Arrb1/Pkd1/Slco4c1/Abca8b/Arrb2/Slc38a1/Atp2b4/Palm/Abcc5/Cav1/Stx2/Nkd2/S100g/Cldn1	33
GO:0043197	dendritic spine	CC	0.146	1.04e-08	2.25e-07	6.65	1.5e-07	Ptprz1/Slc1a3/Gria4/Kcnd2/Kcnd3/Grid2ip/Nlgn1/Lrrc7/Ptpro/Slc8a1/Drd4/P2rx2/Grin2b/Shank2/Ppfia2/Slc8a3/Dock10/Abi2/Nrgn/Sla/Arrb1/Cnn3/Mpp2/Arrb2/Dlg4/Palm/Atp1a2/Gabbr1/Itga8	29
GO:0009925	basal plasma membrane	CC	0.127	1.52e-08	3.04e-07	6.52	2.03e-07	Slc1a3/Slc13a5/Lrrc7/Slc8a1/Cd44/Cdh2/Tek/Cldn8/Ank2/Pth1r/Plpp3/Dlg2/Msn/Slc29a1/Heph/Lin7a/Cd38/Agtr1a/Slc23a2/Arrb1/Pkd1/Slco4c1/Abca8b/Arrb2/Slc38a1/Pkd2/Atp2b4/Palm/Abcc5/Cav1/Stx2/Nkd2/S100g/Itgb4/Cldn1	35
GO:0019897	extrinsic component of plasma membrane	CC	0.151	1.75e-08	3.29e-07	6.48	2.2e-07	Ryr1/Fermt2/Gnai1/Cdh2/Cdh6/Serpine2/Cdh13/Gngt2/Cdh10/Cdh5/Gng11/Sla/Apoe/Cdh11/Gng2/Hip1/Stac2/Dchs1/Gnaz/Fyn/Dlg4/Gng7/Fgr/Zap70/Gnb5/Styk1/Gnb4	27
GO:0044309	neuron spine	CC	0.143	1.84e-08	3.29e-07	6.48	2.2e-07	Ptprz1/Slc1a3/Gria4/Kcnd2/Kcnd3/Grid2ip/Nlgn1/Lrrc7/Ptpro/Slc8a1/Drd4/P2rx2/Grin2b/Shank2/Ppfia2/Slc8a3/Dock10/Abi2/Nrgn/Sla/Arrb1/Cnn3/Mpp2/Arrb2/Dlg4/Palm/Atp1a2/Gabbr1/Itga8	29
GO:1902495	transmembrane transporter complex	CC	0.113	1.84e-08	3.29e-07	6.48	2.2e-07	Kcnb2/Kcnj3/Gria4/Grik1/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/Scn1a/Kcnq5/Cachd1/Cacna2d1/Ano1/Grin2b/Cacna1e/Ano2/Unc80/Ttyh2/Trpc6/Glrb/Gabra4/Scn2a/Grik2/Kcnma1/Kcnc4/Pkd1/Cacng7/Kcnip3/Ryr3/Cacna1h/Cpt1c/Kcng4/Pkd2/Scn3a/Dlg4/Atp1a2/Nrn1/Kcnq4/Cacna1a/Cacnb4	42
GO:0099634	postsynaptic specialization membrane	CC	0.212	2.06e-08	3.57e-07	6.45	2.38e-07	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Ptpro/Cdh2/Lrrc4b/Grin2b/Slitrk3/Dlg2/Nlgn3/Prrt1/Cacng7/Lrfn2/Mpp2/Dlg4	18
GO:0005901	caveola	CC	0.198	2.7e-08	4.53e-07	6.34	3.03e-07	Cacna1c/Kcnd2/Kcnd3/Tfpi/Nos3/Lrrk2/Cdh13/Sele/Kcnma1/Adcyap1r1/Cavin3/Ptch1/Dlc1/Cacna1h/Cavin2/Atp1a2/Plpp1/Cav1/Lipe	19
GO:0098936	intrinsic component of postsynaptic membrane	CC	0.202	4.39e-08	6.92e-07	6.16	4.62e-07	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Ptpro/Nrp1/Cdh2/Lrrc4b/Grin2b/Cacna1e/Slitrk3/Nlgn3/Pcdh17/Lrfn2/Mpp2/Cacna1h	18
GO:0030027	lamellipodium	CC	0.148	4.95e-08	7.57e-07	6.12	5.06e-07	Ptprz1/Evl/Ccdc88a/Cd44/Cdh2/Wasf3/Abi3/Podxl/Plxnd1/Ptprm/Coro1a/Abi2/Sh3bp1/Palld/Carmil3/Arap3/Kitl/Parvb/Dysf/Pkd2/Fgd1/Unc5c/Dpysl3/Arhgap31/Stx2/Plekhh2	26
GO:0099055	integral component of postsynaptic membrane	CC	0.2	1.23e-07	1.78e-06	5.75	1.19e-06	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Ptpro/Nrp1/Cdh2/Lrrc4b/Grin2b/Cacna1e/Slitrk3/Nlgn3/Pcdh17/Lrfn2/Cacna1h	17
GO:0030133	transport vesicle	CC	0.114	1.5e-07	2.05e-06	5.69	1.37e-06	Syn2/Car4/Igf1/Syt13/Aph1b/Stx1b/Sec16b/Lrrk2/Myo5a/Grin2b/Mme/Kif1a/Dlg2/Lin7a/Nrgn/Dmxl2/Prrt1/Syt7/Lyz2/Prrt2/Kcnc4/Bgn/Bin1/Sv2c/Synrg/Lyz1/Septin4/Dlg4/Dpysl3/Brsk1/Rab27a/Stx2/Gabbr1/Slc4a8/Nkd2/Sspn	36
GO:0005938	cell cortex	CC	0.115	1.86e-07	2.49e-06	5.6	1.66e-06	Hmcn1/Ryr1/Rims3/Phldb2/Drd4/Hcls1/Gnai1/Cdh2/Prkd1/Gypc/Exoc3l/Coro1a/Sh3bp1/Sele/Pard6g/Septin3/Rhobtb3/Erc2/BC034090/Pard3b/Asph/Myo1f/Dlc1/Cldn5/Ccn2/Pkd2/Septin4/Dlg4/Mpp1/Arhgef9/Cav1/Usp2/Plekhh2/Itgb4/Shroom1	35
GO:0031253	cell projection membrane	CC	0.112	2.05e-07	2.67e-06	5.57	1.78e-06	Gap43/Ptprz1/Car4/Map2/Evc2/Evc/Epb41l3/Cd44/Aif1l/Abcg2/Adcy3/Shank2/Enpep/Bbs7/Podxl/Lrp2/Pth1r/Thy1/Gabra4/Msn/Jcad/Kcnc4/Eps8l1/Tmem231/Mpp2/Dlc1/Ptger3/Pkd2/Fgr/Palm/Abcb1a/Bbs1/Abcg3/Gabbr1/Itga8/Plekho1	36
GO:0098948	intrinsic component of postsynaptic specialization membrane	CC	0.222	4.05e-07	5.14e-06	5.29	3.43e-06	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Ptpro/Cdh2/Lrrc4b/Grin2b/Slitrk3/Nlgn3/Lrfn2/Mpp2	14
GO:0044853	plasma membrane raft	CC	0.154	4.42e-07	5.47e-06	5.26	3.66e-06	Cacna1c/Kcnd2/Kcnd3/Tfpi/Nos3/Cdh2/Lrrk2/Has2/Cdh13/Sele/Kcnma1/Adcyap1r1/Cavin3/Ptch1/Dlc1/Cacna1h/Cavin2/Atp1a2/Plpp1/Cav1/Lipe	21
GO:0098839	postsynaptic density membrane	CC	0.217	1.43e-06	1.65e-05	4.78	1.1e-05	Grid1/Lrrc4c/Dcc/Ptpro/Lrrc4b/Grin2b/Slitrk3/Dlg2/Prrt1/Cacng7/Lrfn2/Mpp2/Dlg4	13
GO:0099060	integral component of postsynaptic specialization membrane	CC	0.213	1.74e-06	1.97e-05	4.71	1.31e-05	Grid1/Lrrc4c/Kcnd2/Dcc/Kcnd3/Nlgn1/Ptpro/Cdh2/Lrrc4b/Grin2b/Slitrk3/Nlgn3/Lrfn2	13
GO:0098802	plasma membrane signaling receptor complex	CC	0.126	2.87e-06	3.18e-05	4.5	2.12e-05	Gria4/Grik1/Itga4/Itgb7/Grin2b/Cd3g/Itga1/Itgal/Il27ra/Grik2/Emilin1/Itga7/Cacng7/Csf2rb/Cpt1c/Calcrl/Dlg4/Zap70/Apbb1ip/Il12rb1/Nrn1/Gabbr1/Itga8/Itgb4	24
GO:0005912	adherens junction	CC	0.141	3.58e-06	3.88e-05	4.41	2.59e-05	Hmcn1/Fermt2/Cdh2/Cdh6/Cdh10/Cdh5/Ptprm/Msn/Abi2/Lin7a/Esam/Jcad/Sh3bp1/Cdh11/Frmd4b/Pard3b/Dchs1/Frmd4a/Dlg5/Shroom1	20
GO:0005614	interstitial matrix	CC	0.412	3.82e-06	4.05e-05	4.39	2.7e-05	Vit/Col14a1/Igf1/Egflam/Mamdc2/Vwa1/Abi3bp	7
GO:0030055	cell-substrate junction	CC	0.126	4.56e-06	4.74e-05	4.32	3.17e-05	Hmcn1/Evl/Phldb2/Nrp1/Fermt2/Aif1l/Itgb7/Thsd1/Itga1/Tnfsf13b/Msn/Nox4/Sla/Palld/Parvg/Itga7/Efs/Parvb/Tln2/Dlc1/Mapre2/Cav1/Itgb4	23
GO:0016324	apical plasma membrane	CC	0.0976	5.91e-06	5.91e-05	4.23	3.95e-05	Car4/Ddr2/Ptpro/Cd44/Mpdz/P2rx2/Cdh2/Fn1/Slc24a4/Ano1/Stc1/Abcg2/Tek/Shank2/Enpep/Podxl/Lrp2/Pth1r/Thy1/Msn/Slc29a1/Nox4/Kcnma1/Pard6g/Slc23a2/BC034090/Pard3b/Slc38a1/Plpp1/Abcb1a/Rab27a/Abcc5/Cav1/S100g/Cldn1/Shroom1	36
GO:0098982	GABA-ergic synapse	CC	0.188	7.42e-06	7.28e-05	4.14	4.86e-05	Kcnd2/Kcnd3/Ptpro/Plcb1/Slitrk3/Glrb/Gucy1a1/Epha3/Syt7/Erc2/Pcdh17/Arhgef9/Gabbr1	13
GO:0070382	exocytic vesicle	CC	0.114	7.58e-06	7.3e-05	4.14	4.87e-05	Syn2/Igf1/Syt13/Stx1b/Lrrk2/Myo5a/Grin2b/Mme/Kif1a/Dlg2/Dmxl2/Prrt1/Syt7/Prrt2/Kcnc4/Bin1/Sv2c/Septin4/Dlg4/Dpysl3/Brsk1/Rab27a/Stx2/Gabbr1/Slc4a8/Nkd2	26
GO:0030426	growth cone	CC	0.118	9.09e-06	8.59e-05	4.07	5.74e-05	Ptprz1/Map2/Fez1/Itga4/Dcc/Nrp1/Tmod2/Lrrk2/Shank2/Mapk8ip1/Adgrl1/Lrp2/Slc2a13/Thy1/Tshz3/Myo9a/Nin/Ptch1/Erc2/Neo1/Pcdhgb1/Unc5c/Dpysl3/Cpeb1	24
GO:0098889	intrinsic component of presynaptic membrane	CC	0.216	9.6e-06	8.91e-05	4.05	5.95e-05	Efnb3/Kcnj3/Ptprd/Cdh2/Cacna1e/Htr1b/Scn2a/Prrt2/Pcdh17/Cacna1h/Ntng1	11
GO:0034706	sodium channel complex	CC	0.296	1.32e-05	0.00012	3.92	8.04e-05	Gria4/Grik1/Scn4b/Scn1a/Scn2a/Grik2/Cacna1h/Scn3a	8
GO:0098562	cytoplasmic side of membrane	CC	0.118	1.44e-05	0.000129	3.89	8.63e-05	Ryr1/Fermt2/Gnai1/Lrrk2/Rasa3/Gngt2/Msn/Gng11/Kit/Sla/Gng2/Hip1/Stac2/Gnaz/Fyn/Pkd2/Dlg4/Gng7/Fgr/Zap70/Gnb5/Styk1/Gnb4	23
GO:0099056	integral component of presynaptic membrane	CC	0.227	1.49e-05	0.000131	3.88	8.77e-05	Efnb3/Kcnj3/Ptprd/Cdh2/Cacna1e/Htr1b/Scn2a/Prrt2/Pcdh17/Cacna1h	10
GO:0005925	focal adhesion	CC	0.124	1.51e-05	0.000131	3.88	8.77e-05	Evl/Phldb2/Nrp1/Fermt2/Aif1l/Itgb7/Thsd1/Itga1/Tnfsf13b/Msn/Nox4/Sla/Palld/Parvg/Efs/Parvb/Tln2/Dlc1/Mapre2/Cav1/Itgb4	21
GO:0099568	cytoplasmic region	CC	0.111	1.9e-05	0.000158	3.8	0.000105	Gli1/Map2/Rims3/Phldb2/Gnai1/Dzip1l/Arl6/Lrrk2/Wdr35/Bbs7/Dnah5/Gli3/Ift57/Rp1/Grik2/Tubb4a/Dync2h1/Arl3/Erc2/Pkd2/Dlg4/Dnah7b/Dnah1/Dync2li1/Bbs1	25
GO:0034705	potassium channel complex	CC	0.157	2.89e-05	0.000234	3.63	0.000156	Kcnb2/Kcnj3/Gria4/Grik1/Kcna6/Kcnd2/Kcnd3/Kcnq5/Grik2/Kcnma1/Kcnc4/Kcnip3/Kcng4/Kcnq4	14
GO:0043679	axon terminus	CC	0.116	2.92e-05	0.000234	3.63	0.000156	Gria4/Grik1/Kcna6/Slc8a1/Drd4/P2rx2/Lrrk2/Pfn2/Grin2b/Mical1/Slc8a3/Calca/Grik2/Syt7/Kcnma1/Prrt2/Kcnc4/Bin1/Kcnip3/Erc2/Septin4/Slc4a8	22
GO:0009898	cytoplasmic side of plasma membrane	CC	0.119	3.06e-05	0.000241	3.62	0.000161	Ryr1/Fermt2/Gnai1/Rasa3/Gngt2/Msn/Gng11/Kit/Sla/Gng2/Hip1/Stac2/Gnaz/Fyn/Dlg4/Gng7/Fgr/Zap70/Gnb5/Styk1/Gnb4	21
GO:0099146	intrinsic component of postsynaptic density membrane	CC	0.22	5.35e-05	0.000415	3.38	0.000277	Grid1/Lrrc4c/Dcc/Ptpro/Lrrc4b/Grin2b/Slitrk3/Lrfn2/Mpp2	9
GO:0098685	Schaffer collateral - CA1 synapse	CC	0.157	5.78e-05	0.000442	3.35	0.000295	Syn2/Lrrc4c/Dcc/Ptprd/Pfn2/Akap12/Dgkb/Cdh11/Lrfn2/Mpp2/Fyn/Ntng1/Gabbr1	13
GO:0008305	integrin complex	CC	0.235	8.22e-05	0.000602	3.22	0.000402	Itga4/Itgb7/Itga1/Itgal/Emilin1/Itga7/Itga8/Itgb4	8
GO:0043296	apical junction complex	CC	0.117	9.12e-05	0.000658	3.18	0.00044	Clmp/Mpdz/Jam3/Cldn8/Cdh5/Lin7a/Esam/Sh3bp1/Nfasc/Magi2/Adcyap1r1/Frmd4b/Pard6g/Pard3b/Cldn5/Frmd4a/Nphp1/Cldn1/Shroom1	19
GO:0036064	ciliary basal body	CC	0.113	9.32e-05	0.000664	3.18	0.000444	Evc/Ccdc88a/Kif7/Dzip1l/Wdr35/Cibar1/Bbs7/Armc9/Ift57/Rilpl1/Arl3/Cfap410/Ttc26/Ttbk2/Dzip1/Cep19/Pkd2/Dync2li1/Dlg5/Bbs1	20
GO:0005834	heterotrimeric G-protein complex	CC	0.229	0.000103	0.000718	3.14	0.000479	Gnai1/Gngt2/Gng11/Gng2/Gnaz/Gng7/Gnb5/Gnb4	8
GO:0070160	tight junction	CC	0.119	0.000103	0.000718	3.14	0.000479	Clmp/Mpdz/Jam3/Cldn8/Cdh5/Lin7a/Esam/Sh3bp1/Nfasc/Magi2/Adcyap1r1/Frmd4b/Pard6g/Pard3b/Cldn5/Frmd4a/Nphp1/Cldn1	18
GO:0005923	bicellular tight junction	CC	0.123	0.000106	0.000727	3.14	0.000485	Clmp/Mpdz/Jam3/Cldn8/Cdh5/Lin7a/Esam/Sh3bp1/Magi2/Adcyap1r1/Frmd4b/Pard6g/Pard3b/Cldn5/Frmd4a/Nphp1/Cldn1	17
GO:0001726	ruffle	CC	0.118	0.000123	0.000818	3.09	0.000546	Ptprz1/Map2/Cspg4/Aif1l/Myo5a/Podxl/Sh2b2/Rab34/Jcad/Eps8l1/Pecam1/Frmd4b/Arap3/Tln2/Dlc1/Fgd1/Fgr/Plekho1	18
GO:0043195	terminal bouton	CC	0.144	0.000136	0.000892	3.05	0.000596	Gria4/Grik1/Drd4/P2rx2/Lrrk2/Pfn2/Grin2b/Mical1/Calca/Grik2/Kcnma1/Erc2/Slc4a8	13
GO:0034704	calcium channel complex	CC	0.164	0.000137	0.000892	3.05	0.000596	Cacna1c/Ryr1/Cachd1/Cacna2d1/Cacna1e/Pkd1/Cacng7/Ryr3/Cacna1h/Cacna1a/Cacnb4	11
GO:0031594	neuromuscular junction	CC	0.143	0.000152	0.000964	3.02	0.000644	Pdzrn3/Stx1b/Lama4/Serpine2/Tbc1d24/Slc8a3/Postn/Dlg2/Lama2/Kcnc4/Itga7/Dlg4/Ptn	13
GO:1905360	GTPase complex	CC	0.216	0.000156	0.000976	3.01	0.000652	Gnai1/Gngt2/Gng11/Gng2/Gnaz/Gng7/Gnb5/Gnb4	8
GO:0032838	plasma membrane bounded cell projection cytoplasm	CC	0.109	0.000159	0.000984	3.01	0.000657	Gli1/Map2/Dzip1l/Arl6/Lrrk2/Wdr35/Bbs7/Dnah5/Gli3/Ift57/Rp1/Grik2/Tubb4a/Dync2h1/Arl3/Dlg4/Dnah7b/Dnah1/Dync2li1/Bbs1	20
GO:0097731	9+0 non-motile cilium	CC	0.123	0.000169	0.00103	2.99	0.000685	D630045J12Rik/Slc24a4/Myo5a/Tmem237/Shank2/Bbs7/Cerkl/Ift57/Rp1/Arl3/Cfap410/Iqcb1/Nphp1/Gnb5/Rab27a/C130074G19Rik	16
GO:0097733	photoreceptor cell cilium	CC	0.128	0.00017	0.00103	2.99	0.000685	D630045J12Rik/Slc24a4/Myo5a/Tmem237/Shank2/Bbs7/Cerkl/Ift57/Rp1/Arl3/Cfap410/Iqcb1/Nphp1/Gnb5/Rab27a	15
GO:0099061	integral component of postsynaptic density membrane	CC	0.205	0.00023	0.00136	2.87	0.000907	Grid1/Lrrc4c/Dcc/Ptpro/Lrrc4b/Grin2b/Slitrk3/Lrfn2	8
GO:0008021	synaptic vesicle	CC	0.102	0.000252	0.00147	2.83	0.000985	Syn2/Stx1b/Lrrk2/Myo5a/Grin2b/Mme/Kif1a/Dlg2/Dmxl2/Prrt1/Syt7/Prrt2/Kcnc4/Bin1/Sv2c/Septin4/Dlg4/Brsk1/Stx2/Gabbr1/Slc4a8	21
GO:0016342	catenin complex	CC	0.226	0.000302	0.00175	2.76	0.00117	Cdh2/Cdh6/Cdh13/Cdh10/Cdh5/Cdh11/Dchs1	7
GO:0097730	non-motile cilium	CC	0.108	0.000367	0.00208	2.68	0.00139	D630045J12Rik/Slc24a4/Myo5a/Tmem237/Shank2/Bbs7/Cerkl/Ano2/Ift57/Rp1/Arl3/Cfap410/Pkd2/Iqcb1/Nphp1/Gnb5/Rab27a/C130074G19Rik	18
GO:0008076	voltage-gated potassium channel complex	CC	0.147	0.000381	0.00213	2.67	0.00142	Kcnb2/Kcnj3/Kcna6/Kcnd2/Kcnd3/Kcnq5/Kcnma1/Kcnc4/Kcnip3/Kcng4/Kcnq4	11
GO:0097014	ciliary plasm	CC	0.113	0.00043	0.00238	2.62	0.00159	Gli1/Dzip1l/Arl6/Wdr35/Bbs7/Dnah5/Gli3/Ift57/Rp1/Tubb4a/Dync2h1/Arl3/Dnah7b/Dnah1/Dync2li1/Bbs1	16
GO:0005874	microtubule	CC	0.0799	0.000434	0.00238	2.62	0.00159	Map2/Fez1/Capn6/Clmp/Slc8a1/Kif7/Cep170/Dnah5/Klhl22/Slc8a3/Kif26a/Kif1a/Reep1/Eml1/Map9/Tubb4a/Apoe/Kif6/Dync2h1/Katnal1/Slain1/Ninl/Nin/Arl3/Sarm1/Dysf/Stard9/Dnah1/Dync2li1/Lrrc49/Tcp11l1/Mapre2/Tppp/Kif16b/Shroom1	35
GO:0098791	Golgi apparatus subcompartment	CC	0.0879	0.000446	0.0024	2.62	0.0016	B4galnt4/Car4/Nsg2/Chst2/Tgfbi/Bok/Lrrk2/Slc9a7/Gga2/Prkd1/Ap1m1/Postn/Rab34/Plpp3/Mme/Chst1/Cracr2a/Ggta1/Lyz2/Dennd5a/Pcsk5/Ms4a7/Nsg1/5730455P16Rik/Lyz1/Ece2/Xylt1	27
GO:0098858	actin-based cell projection	CC	0.0961	0.000448	0.0024	2.62	0.0016	Gap43/Ptprz1/Map2/Angpt1/Nlgn1/Lrrc7/Cd44/Lrrk2/Myo5a/Tek/Jam3/Podxl/Msn/Coro1a/Abi2/Nfasc/Lyz2/Kitl/Myo1f/Lyz1/Unc5c/Palm	22
GO:0005891	voltage-gated calcium channel complex	CC	0.186	0.000464	0.00246	2.61	0.00165	Cacna1c/Cachd1/Cacna2d1/Cacna1e/Cacng7/Cacna1h/Cacna1a/Cacnb4	8
GO:0008328	ionotropic glutamate receptor complex	CC	0.182	0.000546	0.00284	2.55	0.0019	Gria4/Grik1/Grin2b/Grik2/Cacng7/Cpt1c/Dlg4/Nrn1	8
GO:0016327	apicolateral plasma membrane	CC	0.24	0.000578	0.00298	2.53	0.00199	Mpdz/Cdh2/Cldn8/Prickle2/Cldn5/Palm	6
GO:0001518	voltage-gated sodium channel complex	CC	0.294	0.000614	0.00313	2.5	0.00209	Scn4b/Scn1a/Scn2a/Cacna1h/Scn3a	5
GO:0043292	contractile fiber	CC	0.0928	0.000712	0.00359	2.44	0.0024	Cacna1c/Ryr1/Adra1a/Npnt/Slc8a1/Pygm/Tmod2/Scn1a/Mmp2/Mef2c/Grin2b/Arhgef25/Ank2/Palld/Pecam1/Myl3/Cmya5/Bin1/Ryr3/Atp2b4/Habp4/Simc1	22
GO:0098878	neurotransmitter receptor complex	CC	0.174	0.000745	0.00369	2.43	0.00246	Gria4/Grik1/Grin2b/Grik2/Cacng7/Cpt1c/Dlg4/Nrn1	8
GO:0030863	cortical cytoskeleton	CC	0.115	0.000859	0.0042	2.38	0.0028	Rims3/Hcls1/Cdh2/Gypc/Coro1a/Sele/Erc2/Myo1f/Dlc1/Cldn5/Dlg4/Mpp1/Plekhh2/Shroom1	14
GO:0032391	photoreceptor connecting cilium	CC	0.17	0.000864	0.0042	2.38	0.0028	D630045J12Rik/Tmem237/Ift57/Rp1/Arl3/Cfap410/Iqcb1/Nphp1	8
GO:0048787	presynaptic active zone membrane	CC	0.214	0.0011	0.00525	2.28	0.00351	Stx1b/Cdh2/Kcnma1/Cacna1h/Ntng1/Stx2	6
GO:0016528	sarcoplasm	CC	0.129	0.00112	0.00529	2.28	0.00353	Car4/Sgcd/Ryr1/Jph4/Pygm/Cacna2d1/Cmya5/Asph/Ryr3/Flnc/Gstm7	11
GO:0030175	filopodium	CC	0.121	0.00122	0.00571	2.24	0.00381	Gap43/Ptprz1/Map2/Nlgn1/Lrrc7/Myo5a/Podxl/Msn/Abi2/Kitl/Unc5c/Palm	12
GO:0042613	MHC class II protein complex	CC	0.333	0.00133	0.00616	2.21	0.00412	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0000137	Golgi cis cisterna	CC	0.308	0.00185	0.00852	2.07	0.00569	Nsg2/Lyz2/Lyz1/Xylt1	4
GO:0031045	dense core granule	CC	0.194	0.00193	0.00876	2.06	0.00585	Cpe/Kif1a/Cadps/Dmxl2/Syt7/Ncs1	6
GO:0030016	myofibril	CC	0.0893	0.00194	0.00876	2.06	0.00585	Cacna1c/Ryr1/Adra1a/Slc8a1/Pygm/Tmod2/Scn1a/Mmp2/Mef2c/Grin2b/Arhgef25/Ank2/Palld/Myl3/Cmya5/Bin1/Ryr3/Atp2b4/Habp4/Simc1	20
GO:0005884	actin filament	CC	0.105	0.00198	0.00888	2.05	0.00593	Hcls1/Aif1l/Myo5a/Tek/Jam3/Sh2b2/Coro1a/Abi2/Palld/Myo1f/Dlc1/Fyn/Wipf1/Dpysl3	14
GO:0005802	trans-Golgi network	CC	0.0854	0.00261	0.0116	1.93	0.00776	Car4/Nsg2/Chst2/Tgfbi/Bok/Lrrk2/Slc9a7/Gga2/Prkd1/Ap1m1/Postn/Plpp3/Mme/Chst1/Cracr2a/Dennd5a/Pcsk5/Ms4a7/Nsg1/5730455P16Rik/Ece2	21
GO:0044295	axonal growth cone	CC	0.159	0.0027	0.0118	1.93	0.00787	Dcc/Mapk8ip1/Lrp2/Myo9a/Nin/Ptch1/Neo1	7
GO:0060170	ciliary membrane	CC	0.14	0.0031	0.0133	1.88	0.00889	Evc2/Evc/Adcy3/Shank2/Bbs7/Tmem231/Pkd2/Bbs1	8
GO:0005814	centriole	CC	0.102	0.0036	0.0153	1.81	0.0102	Ccdc88a/Dzip1l/Cibar1/Cep170/Cntln/Armc9/Crocc/Nin/Ttbk2/Dzip1/Cep19/Stard9/Cep97	13
GO:0005790	smooth endoplasmic reticulum	CC	0.171	0.00366	0.0155	1.81	0.0103	Map2/Ryr1/Jph4/Rtn1/Myo5a/Ryr3	6
GO:0046658	anchored component of plasma membrane	CC	0.125	0.00391	0.0164	1.79	0.0109	Gpc6/Car4/Gpc3/Thy1/Rtn4rl1/Mpp2/Ntng1/Gpc2/Nrn1	9
GO:0019867	outer membrane	CC	0.0861	0.00464	0.019	1.72	0.0127	Acsl6/Maob/Bok/Lrrk2/Maoa/Slc8a3/Armcx6/Armcx1/Agtr1a/Snn/Aifm2/Sarm1/Syne3/Cpt1c/Armcx2/Asl/Gimap3/Acsl1	18
GO:0031968	organelle outer membrane	CC	0.0861	0.00464	0.019	1.72	0.0127	Acsl6/Maob/Bok/Lrrk2/Maoa/Slc8a3/Armcx6/Armcx1/Agtr1a/Snn/Aifm2/Sarm1/Syne3/Cpt1c/Armcx2/Asl/Gimap3/Acsl1	18
GO:0031985	Golgi cisterna	CC	0.131	0.00474	0.0191	1.72	0.0128	B4galnt4/Nsg2/Rab34/Ggta1/Lyz2/Pcsk5/Lyz1/Xylt1	8
GO:0032809	neuronal cell body membrane	CC	0.158	0.00558	0.0222	1.65	0.0148	Kcnb2/Slc6a2/Kcnd2/Thy1/Kcnc4/Slc4a8	6
GO:0016529	sarcoplasmic reticulum	CC	0.118	0.00561	0.0222	1.65	0.0148	Car4/Sgcd/Ryr1/Pygm/Cacna2d1/Cmya5/Asph/Ryr3/Gstm7	9
GO:0030667	secretory granule membrane	CC	0.111	0.00568	0.0222	1.65	0.0148	Car4/Slc2a3/Cpe/Kif1a/Msn/Cd38/Pla1a/Ccdc136/Rab27a/Cav1	10
GO:0044291	cell-cell contact zone	CC	0.111	0.00568	0.0222	1.65	0.0148	Slc8a1/Scn4b/Cdh2/Scn1a/Jam3/Ank2/Scn2a/Pecam1/Tln2/Atp1a2	10
GO:0005902	microvillus	CC	0.105	0.00597	0.0232	1.63	0.0155	Angpt1/Cd44/Lrrk2/Tek/Jam3/Podxl/Msn/Nfasc/Lyz2/Myo1f/Lyz1	11
GO:0043083	synaptic cleft	CC	0.222	0.00666	0.0257	1.59	0.0171	Lama4/Grin2b/Lama2/Apoe	4
GO:0032281	AMPA glutamate receptor complex	CC	0.172	0.00765	0.029	1.54	0.0194	Gria4/Cacng7/Cpt1c/Dlg4/Nrn1	5
GO:0099569	presynaptic cytoskeleton	CC	0.3	0.00781	0.029	1.54	0.0194	Rims3/Septin3/Erc2	3
GO:1990454	L-type voltage-gated calcium channel complex	CC	0.3	0.00781	0.029	1.54	0.0194	Cacna1c/Cacna2d1/Cacng7	3
GO:0031526	brush border membrane	CC	0.112	0.00783	0.029	1.54	0.0194	Car4/Abcg2/Shank2/Enpep/Lrp2/Pth1r/Ptger3/Abcb1a/Abcg3	9
GO:0098644	complex of collagen trimers	CC	0.211	0.00816	0.0293	1.53	0.0196	Col11a1/Col4a6/Col16a1/Col5a2	4
GO:0005741	mitochondrial outer membrane	CC	0.0851	0.00817	0.0293	1.53	0.0196	Acsl6/Maob/Bok/Lrrk2/Maoa/Slc8a3/Armcx6/Armcx1/Snn/Aifm2/Sarm1/Cpt1c/Armcx2/Asl/Gimap3/Acsl1	16
GO:0014704	intercalated disc	CC	0.119	0.00837	0.0298	1.53	0.0199	Slc8a1/Scn4b/Cdh2/Scn1a/Ank2/Scn2a/Tln2/Atp1a2	8
GO:0016010	dystrophin-associated glycoprotein complex	CC	0.2	0.00985	0.0348	1.46	0.0233	Sgcd/Sntb1/Sgcb/Sspn	4
GO:0005583	fibrillar collagen trimer	CC	0.273	0.0104	0.0363	1.44	0.0242	Col11a1/Col16a1/Col5a2	3
GO:0098643	banded collagen fibril	CC	0.273	0.0104	0.0363	1.44	0.0242	Col11a1/Col16a1/Col5a2	3
GO:0005903	brush border	CC	0.0897	0.0108	0.037	1.43	0.0247	Car4/Dab1/Abcg2/Shank2/Enpep/Lrp2/Pth1r/Mme/Scart1/Scin/Ptger3/Abcb1a/Abcg3	13
GO:0032589	neuron projection membrane	CC	0.111	0.0127	0.0429	1.37	0.0287	Epb41l3/Thy1/Gabra4/Kcnc4/Mpp2/Palm/Gabbr1/Itga8	8
GO:0031225	anchored component of membrane	CC	0.0829	0.0128	0.0431	1.37	0.0288	Gpc6/Cntn3/Car4/Cd109/Sema7a/Gpc3/Ntm/Cdh13/Thy1/Rtn4rl1/Mmp19/Mpp2/Ntng1/Gpc2/Nrn1	15
GO:0098945	intrinsic component of presynaptic active zone membrane	CC	0.25	0.0134	0.0444	1.35	0.0297	Cdh2/Cacna1h/Ntng1	3
GO:0032587	ruffle membrane	CC	0.11	0.0137	0.0452	1.34	0.0302	Ptprz1/Map2/Aif1l/Jcad/Eps8l1/Dlc1/Fgr/Plekho1	8
GO:0050839	cell adhesion molecule binding	MF	0.179	2.25e-19	2.05e-16	15.7	1.59e-16	Prtg/Ptprz1/Itga4/Lrrc4c/Kdr/Ptprd/Igf1/Nlgn1/Npnt/Nos3/Ptpro/Sema7a/Fermt2/Tgfbi/Cdh2/Fxyd5/Cdh6/Itgb7/Fn1/Tenm3/Col16a1/Icam1/Grin2b/Cxcl12/Jam3/Cdh13/Cdh10/Adgrl1/Itga1/Cdh5/Postn/Cpe/Thy1/Plpp3/Cd1d1/Ptprm/Msn/Cd226/Nlgn3/Esam/Itgal/Nfasc/Cdh11/Emilin1/Cd200/Igf2/Itga7/Tln2/Dchs1/Neo1/Ccn2/Ptn/Ntng1/Itga8/Itgb4	55
GO:0046873	metal ion transmembrane transporter activity	MF	0.133	8.27e-14	3.77e-11	10.4	2.93e-11	Kcnk3/Kcnb2/Nalcn/Kcnj3/Slc1a3/Grik1/Kcna6/Cacna1c/Slc6a2/Kcnd2/Slc5a11/Slc13a5/Ryr1/Kcnd3/Slc12a8/Slc8a1/Scn4b/Scn1a/Slc24a4/Kcnq5/Cachd1/Cacna2d1/Slc9a7/Rasa3/Grin2b/Slc24a3/Cacna1e/Slc8a3/Htr1b/Nalf1/Slc6a15/Trpc6/Scn2a/Grik2/Kcnma1/Slc9a5/Kcnc4/Slc23a2/Pkd1/Cacng7/Kcnip3/Ncs1/Ryr3/Cacna1h/Kcng4/Slc38a1/Pkd2/Slc12a4/Scn3a/Atp2b4/Atp1a2/Pkdrej/Kcnq4/Slc4a8/Cacna1a/Cacnb4	56
GO:0005261	cation channel activity	MF	0.138	3.66e-12	1.06e-09	8.97	8.26e-10	Kcnk3/Kcnb2/Nalcn/Kcnj3/Gria4/Grik1/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Scn1a/Slc24a4/Kcnq5/Cachd1/Cacna2d1/Ano1/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpm3/Unc80/Htr1b/Nalf1/Trpc6/Scn2a/Grik2/Kcnma1/Kcnc4/Pkd1/Cacng7/Kcnip3/Ncs1/Ryr3/Cacna1h/Kcng4/Pkd2/Scn3a/Pkdrej/Piezo2/Kcnq4/Cacna1a/Cacnb4	46
GO:0022836	gated channel activity	MF	0.139	4.66e-12	1.06e-09	8.97	8.26e-10	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Gria4/Grik1/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Scn1a/Kcnq5/Cachd1/Cacna2d1/Ano1/Rasa3/Grin2b/Cacna1e/Ano2/Htr1b/Ttyh2/Nalf1/Glrb/Gabra4/Scn2a/Grik2/Kcnma1/Kcnc4/Cacng7/Kcnip3/Ncs1/Ryr3/Cacna1h/Kcng4/Pkd2/Scn3a/Clca2/Piezo2/Kcnq4/Cacna1a/Cacnb4	45
GO:0005216	ion channel activity	MF	0.121	1.57e-11	2.86e-09	8.54	2.22e-09	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Gria4/Grik1/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Scn1a/Slc24a4/Kcnq5/Cachd1/Cacna2d1/Ano1/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpm3/Ano2/Unc80/Htr1b/Ttyh2/Nalf1/Trpc6/Glrb/Gabra4/Scn2a/Grik2/Kcnma1/Kcnc4/Gjc1/Pkd1/Cacng7/Kcnip3/Ncs1/Ryr3/Cacna1h/Kcng4/Pkd2/Scn3a/Clca2/Pkdrej/Piezo2/Kcnq4/Cacna1a/Cacnb4	53
GO:0015267	channel activity	MF	0.114	6.35e-11	7.24e-09	8.14	5.62e-09	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Gria4/Grik1/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Scn1a/Slc24a4/Kcnq5/Cachd1/Cacna2d1/Ano1/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpm3/Ano2/Unc80/Htr1b/Ttyh2/Nalf1/Trpc6/Glrb/Gabra4/Scn2a/Gja4/Grik2/Kcnma1/Kcnc4/Gjc1/Pkd1/Cacng7/Kcnip3/Ncs1/Ryr3/Aqp11/Cacna1h/Kcng4/Pkd2/Scn3a/Clca2/Pkdrej/Piezo2/Kcnq4/Cacna1a/Cacnb4	55
GO:0022803	passive transmembrane transporter activity	MF	0.114	6.35e-11	7.24e-09	8.14	5.62e-09	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Gria4/Grik1/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/P2rx2/Scn1a/Slc24a4/Kcnq5/Cachd1/Cacna2d1/Ano1/Rasa3/Grin2b/Slc24a3/Cacna1e/Trpm3/Ano2/Unc80/Htr1b/Ttyh2/Nalf1/Trpc6/Glrb/Gabra4/Scn2a/Gja4/Grik2/Kcnma1/Kcnc4/Gjc1/Pkd1/Cacng7/Kcnip3/Ncs1/Ryr3/Aqp11/Cacna1h/Kcng4/Pkd2/Scn3a/Clca2/Pkdrej/Piezo2/Kcnq4/Cacna1a/Cacnb4	55
GO:0005244	voltage-gated ion channel activity	MF	0.161	2.44e-10	2.48e-08	7.61	1.92e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/Scn1a/Kcnq5/Cachd1/Cacna2d1/Ano1/Grin2b/Cacna1e/Htr1b/Scn2a/Kcnma1/Kcnc4/Cacng7/Kcnip3/Ncs1/Cacna1h/Kcng4/Pkd2/Scn3a/Kcnq4/Cacna1a/Cacnb4	31
GO:0022832	voltage-gated channel activity	MF	0.161	2.79e-10	2.55e-08	7.59	1.98e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Scn4b/Scn1a/Kcnq5/Cachd1/Cacna2d1/Ano1/Grin2b/Cacna1e/Htr1b/Scn2a/Kcnma1/Kcnc4/Cacng7/Kcnip3/Ncs1/Cacna1h/Kcng4/Pkd2/Scn3a/Kcnq4/Cacna1a/Cacnb4	31
GO:0005178	integrin binding	MF	0.174	6.15e-10	5.1e-08	7.29	3.96e-08	Ptprz1/Itga4/Kdr/Igf1/Npnt/Sema7a/Fermt2/Tgfbi/Itgb7/Fn1/Col16a1/Icam1/Cxcl12/Jam3/Itga1/Thy1/Plpp3/Cd226/Itgal/Emilin1/Igf2/Itga7/Tln2/Ccn2/Ptn/Itga8/Itgb4	27
GO:0003779	actin binding	MF	0.113	7.42e-10	5.64e-08	7.25	4.38e-08	Lsp1/Myo16/Map2/Slc6a2/Evl/Epb41l3/Nos3/Ccdc88a/Hcls1/Fermt2/Aif1l/Tmod2/Fxyd5/Wasf3/Lrrk2/Myo5a/Pfn2/Mical1/Vash1/Trpc6/Msn/Coro1a/Sntb1/Myo9a/Limch1/Palld/Kcnma1/Eps8l1/Daam2/Scin/Parvg/Myl3/Cap2/Crocc/Cnn2/Hip1/Parvb/Bin1/Syne3/Rai14/Myo1f/Flnc/Cnn3/Tln2/Wipf1/Pknox2/Actr3b/Plekhh2/Vash2/Shroom1	50
GO:0005539	glycosaminoglycan binding	MF	0.142	2.12e-09	1.49e-07	6.83	1.16e-07	Apob/Col11a1/Vit/Sema5a/Mdk/Thbs3/Cd44/Spock2/Nrp1/Fn1/Serpine2/Egflam/Adamts1/Nell1/Col13a1/Mamdc2/Postn/Smoc1/Apoe/Layn/Ndnf/Rtn4rl1/Tnfaip6/Bgn/Ptch1/Hapln3/Abi3bp/Ccn2/Dpysl3/Fstl1/Efemp2/Habp4/Ptn	33
GO:0005096	GTPase activator activity	MF	0.14	2.95e-09	1.86e-07	6.73	1.45e-07	Wnt11/Agap2/Rgs6/Rgs16/Rasgrp3/Nrp1/Garnl3/Lrrk2/Rasa3/Arhgap45/Tbc1d24/Plcb1/Arhgap25/Dock2/Thy1/Syde1/Myo9a/Sh3bp1/Rgs5/Arhgef15/Arhgap6/Nckap1l/Arap3/Prex2/Arrb1/Arhgap10/Arhgap28/Dlc1/Gnb5/Arhgap31/Syngap1/Arhgap15/Arfgap3	33
GO:0015085	calcium ion transmembrane transporter activity	MF	0.179	3.07e-09	1.86e-07	6.73	1.45e-07	Cacna1c/Ryr1/Slc8a1/Slc24a4/Cachd1/Cacna2d1/Rasa3/Grin2b/Slc24a3/Cacna1e/Slc8a3/Htr1b/Nalf1/Trpc6/Pkd1/Cacng7/Ncs1/Ryr3/Cacna1h/Pkd2/Atp2b4/Pkdrej/Cacna1a/Cacnb4	24
GO:0005516	calmodulin binding	MF	0.151	4.48e-09	2.55e-07	6.59	1.98e-07	Gap43/Map2/Cacna1c/Ryr1/Nos3/Slc8a1/Slc24a4/Kcnq5/Myo5a/Pde1b/Adcy3/Akap12/Slc8a3/Plcb1/Cth/Sntb1/Nrgn/Pde1a/Syt7/Cnn2/Myo1f/Ryr3/Cnn3/Rrad/Scn3a/Iqcb1/Atp2b4/Kcnq4/Cacna1a	29
GO:0030695	GTPase regulator activity	MF	0.109	9.82e-09	4.85e-07	6.31	3.77e-07	Wnt11/Agap2/Ccdc88a/Rgs6/Rgs16/Rasgrp3/Nrp1/Garnl3/Lrrk2/Rasa3/Arhgap45/Arhgef25/Tbc1d24/Plcb1/Rasgrp2/Arhgap25/Dock2/Thy1/Syde1/Dock10/Denn2b/Myo9a/Sh3bp1/Rgs5/Arhgef15/Arhgap6/Eps8l1/Arhgef40/Dennd5a/Nckap1l/Arap3/Prex2/Arrb1/Arhgap10/Arhgap28/Dlc1/Net1/Fgd1/Gnb5/Arhgap31/Syngap1/Ngef/Fgd5/Arhgef9/Arhgap15/Arfgap3	46
GO:0060589	nucleoside-triphosphatase regulator activity	MF	0.109	9.82e-09	4.85e-07	6.31	3.77e-07	Wnt11/Agap2/Ccdc88a/Rgs6/Rgs16/Rasgrp3/Nrp1/Garnl3/Lrrk2/Rasa3/Arhgap45/Arhgef25/Tbc1d24/Plcb1/Rasgrp2/Arhgap25/Dock2/Thy1/Syde1/Dock10/Denn2b/Myo9a/Sh3bp1/Rgs5/Arhgef15/Arhgap6/Eps8l1/Arhgef40/Dennd5a/Nckap1l/Arap3/Prex2/Arrb1/Arhgap10/Arhgap28/Dlc1/Net1/Fgd1/Gnb5/Arhgap31/Syngap1/Ngef/Fgd5/Arhgef9/Arhgap15/Arfgap3	46
GO:0022843	voltage-gated cation channel activity	MF	0.169	1.01e-08	4.85e-07	6.31	3.77e-07	Kcnk3/Kcnb2/Kcnj3/Kcna6/Cacna1c/Kcnd2/Ryr1/Kcnd3/Kcnq5/Cachd1/Cacna2d1/Grin2b/Cacna1e/Htr1b/Kcnma1/Kcnc4/Cacng7/Ncs1/Cacna1h/Kcng4/Pkd2/Kcnq4/Cacna1a/Cacnb4	24
GO:0015081	sodium ion transmembrane transporter activity	MF	0.166	1.54e-08	7.03e-07	6.15	5.46e-07	Nalcn/Slc1a3/Grik1/Slc6a2/Slc5a11/Slc13a5/Slc8a1/Scn4b/Scn1a/Slc24a4/Slc9a7/Slc24a3/Slc8a3/Slc6a15/Scn2a/Grik2/Slc9a5/Slc23a2/Cacna1h/Slc38a1/Pkd2/Scn3a/Atp1a2/Slc4a8	24
GO:0005262	calcium channel activity	MF	0.181	2.41e-08	1.05e-06	5.98	8.12e-07	Cacna1c/Ryr1/Slc24a4/Cachd1/Cacna2d1/Rasa3/Grin2b/Slc24a3/Cacna1e/Htr1b/Nalf1/Trpc6/Pkd1/Cacng7/Ncs1/Ryr3/Cacna1h/Pkd2/Pkdrej/Cacna1a/Cacnb4	21
GO:0008237	metallopeptidase activity	MF	0.141	1.23e-07	5.1e-06	5.29	3.96e-06	Cpxm2/Mmp16/Adamts20/Adamts16/Adamts19/Mmp2/Enpep/Adam33/Adamts1/Vash1/Cpe/Naalad2/Mme/Adamts10/Adamts7/Adam11/Trhde/Agbl3/Mmp19/Ece2/Adam19/Pappa/Clca2/Adamts17/Lvrn/Vash2	26
GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	MF	0.108	4.41e-07	1.67e-05	4.78	1.3e-05	Lef1/Tbx2/Zeb2/Prdm5/Zfp37/Hoxd9/Osr2/Klf8/Zfp239/Glis1/Tcf21/Bcl6b/Zeb1/Prdm1/Zfp248/Zfp13/Tbx3/Heyl/Snai1/Zbtb46/Irf8/Satb1/Klf12/Peg3/Foxs1/Zfp382/Zbtb20/Kcnip3/Nr2f1/Nfatc4/Cux2/Ets2/Zbtb8a/Zfp566/Zfp512b/Zfp90	36
GO:0005245	voltage-gated calcium channel activity	MF	0.255	5.17e-07	1.88e-05	4.72	1.46e-05	Cacna1c/Ryr1/Cachd1/Cacna2d1/Cacna1e/Htr1b/Cacng7/Ncs1/Cacna1h/Pkd2/Cacna1a/Cacnb4	12
GO:0001217	DNA-binding transcription repressor activity	MF	0.107	5.48e-07	1.92e-05	4.72	1.49e-05	Lef1/Tbx2/Zeb2/Prdm5/Zfp37/Hoxd9/Osr2/Klf8/Zfp239/Glis1/Tcf21/Bcl6b/Zeb1/Prdm1/Zfp248/Zfp13/Tbx3/Heyl/Snai1/Zbtb46/Irf8/Satb1/Klf12/Peg3/Foxs1/Zfp382/Zbtb20/Kcnip3/Nr2f1/Nfatc4/Cux2/Ets2/Zbtb8a/Zfp566/Zfp512b/Zfp90	36
GO:0015079	potassium ion transmembrane transporter activity	MF	0.14	1.18e-06	3.99e-05	4.4	3.1e-05	Kcnk3/Kcnb2/Kcnj3/Grik1/Kcna6/Kcnd2/Kcnd3/Slc12a8/Slc24a4/Kcnq5/Slc9a7/Slc24a3/Grik2/Kcnma1/Slc9a5/Kcnc4/Kcnip3/Kcng4/Pkd2/Slc12a4/Atp1a2/Kcnq4	22
GO:0008373	sialyltransferase activity	MF	0.381	1.46e-06	4.77e-05	4.32	3.7e-05	St6gal2/St8sia2/St8sia4/St6galnac4/St3gal2/St8sia6/St6galnac6/St3gal4	8
GO:0030020	extracellular matrix structural constituent conferring tensile strength	MF	0.263	3.42e-06	0.000108	3.97	8.37e-05	Col11a1/Col14a1/Col4a6/Col16a1/Col9a2/Col13a1/Col5a2/Col15a1/Col23a1/Col18a1	10
GO:0017124	SH3 domain binding	MF	0.143	4.65e-06	0.000141	3.85	0.00011	Evl/Drd4/Hcls1/Abi3/Mical1/Shank2/Lrp2/Abi2/Sh3bp1/Afap1l1/Arhgap6/Prrt2/Efs/Wipf1/Afap1l2/Adam19/Dpysl3/Arhgap31/Syngap1	19
GO:0016757	glycosyltransferase activity	MF	0.108	5.87e-06	0.000173	3.76	0.000134	B4galnt4/St6gal2/St8sia2/St8sia4/Gxylt2/Uggt2/Pygm/Tmtc1/B3galnt1/B4galt2/Fut10/Has2/Galnt16/St6galnac4/St3gal2/Lfng/Eogt/Ggta1/Lacc1/St8sia6/Galntl6/Poglut2/Mgat3/B3gnt5/Xylt1/Mfng/St6galnac6/St3gal4/Large1	29
GO:0045296	cadherin binding	MF	0.188	6.98e-06	0.000199	3.7	0.000155	Kdr/Nos3/Ptpro/Cdh2/Fxyd5/Cdh6/Cdh13/Cdh10/Cdh5/Ptprm/Cdh11/Dchs1/Neo1	13
GO:0001664	G protein-coupled receptor binding	MF	0.1	1.04e-05	0.000278	3.56	0.000216	Cxcl15/Ndp/Wnt6/Wnt11/Ptch2/Gprasp2/Tub/Gnai1/Ednrb/Grin2b/Cxcl12/Edn3/Cnrip1/Calca/Wnt9a/Reep1/Znrf3/Agtr1a/Magi2/Bdkrb2/Xcl1/Arrb1/Ptch1/Gnaz/Arrb2/Fyn/Apln/Dlg4/Palm/Nes/Bbs1/Itgb4	32
GO:0019838	growth factor binding	MF	0.131	1.04e-05	0.000278	3.56	0.000216	Epha8/Ptprz1/Cd109/Kdr/Nrp1/Il11ra1/Tek/Lrp2/Flt3/Epha3/Tsku/Ltbp3/Epha7/Nrros/Ccn2/Ptn/Il2rg/Nkd2/Igfbp4/Itgb4	20
GO:0004222	metalloendopeptidase activity	MF	0.151	1.27e-05	0.000331	3.48	0.000257	Mmp16/Adamts20/Adamts16/Adamts19/Mmp2/Adam33/Adamts1/Mme/Adamts10/Adamts7/Adam11/Mmp19/Ece2/Adam19/Pappa/Adamts17	16
GO:0008201	heparin binding	MF	0.124	1.52e-05	0.000386	3.41	3e-04	Apob/Col11a1/Mdk/Thbs3/Nrp1/Fn1/Serpine2/Adamts1/Nell1/Col13a1/Postn/Smoc1/Apoe/Ndnf/Rtn4rl1/Ptch1/Abi3bp/Ccn2/Fstl1/Efemp2/Ptn	21
GO:0044325	transmembrane transporter binding	MF	0.129	2.01e-05	0.000496	3.3	0.000385	Kcnb2/Cacna1c/Kcnd3/Tcaf1/Rims3/Slc8a1/Scn4b/Lrrk2/Ank2/Cdh5/Arrb1/Pkd1/Kcnip3/Fhl1/Mpp2/Kcng4/Fyn/Pkd2/Cav1	19
GO:0098879	structural constituent of postsynaptic specialization	MF	0.5	3.14e-05	0.000754	3.12	0.000586	Shank2/Dlg2/Magi2/Mpp2/Dlg4	5
GO:0004713	protein tyrosine kinase activity	MF	0.133	3.81e-05	0.000868	3.06	0.000674	Epha8/Kdr/Pkdcc/Ddr2/Nrp1/Itk/Tek/Flt3/Kit/Epha3/Tie1/Hipk2/Epha7/Fyn/Fgr/Zap70/Styk1	17
GO:0035591	signaling adaptor activity	MF	0.171	4.21e-05	0.000934	3.03	0.000725	Lrrk2/Shank2/Akap12/Mapk8ip1/Sh2b2/Abi2/Magi2/Sarm1/Afap1l2/Gnb5/Lat/Gnb4	12
GO:0008509	anion transmembrane transporter activity	MF	0.0958	4.3e-05	0.000934	3.03	0.000725	Slc1a3/Grik1/Slc6a2/Slc13a5/Slc2a3/Slc12a8/Slc24a4/Slc9a7/Ano1/Slc7a2/Abcg2/Slc24a3/Slc36a4/Ano2/Ttyh2/Glrb/Gabra4/Slc29a1/Slc9a5/Slc23a2/Sfxn5/Slco4c1/Slc4a3/Slc38a1/Slc12a4/Slc25a23/Clca2/Abcc5/Abcg3/Slc4a8	30
GO:0005248	voltage-gated sodium channel activity	MF	0.28	6.7e-05	0.00139	2.86	0.00108	Nalcn/Scn4b/Scn1a/Scn2a/Cacna1h/Pkd2/Scn3a	7
GO:0016849	phosphorus-oxygen lyase activity	MF	0.28	6.7e-05	0.00139	2.86	0.00108	Gucy1a2/Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7/Cd38	7
GO:0005080	protein kinase C binding	MF	0.172	8.5e-05	0.00172	2.76	0.00134	Fez1/Ccdc88a/Nell1/Adcy4/Pard6g/Hdac9/Cavin3/BC034090/Cavin2/Akt3/Dact1	11
GO:0004016	adenylate cyclase activity	MF	0.417	9.18e-05	0.00175	2.76	0.00136	Adcy3/Gucy1b1/Gucy1a1/Adcy4/Adcy7	5
GO:0005272	sodium channel activity	MF	0.205	9.22e-05	0.00175	2.76	0.00136	Nalcn/Grik1/Scn4b/Scn1a/Scn2a/Grik2/Cacna1h/Pkd2/Scn3a	9
GO:0099511	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	MF	0.385	0.000144	0.00262	2.58	0.00204	Cacna1e/Htr1b/Ncs1/Cacna1a/Cacnb4	5
GO:0099626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	MF	0.385	0.000144	0.00262	2.58	0.00204	Cacna1e/Htr1b/Ncs1/Cacna1a/Cacnb4	5
GO:0004714	transmembrane receptor protein tyrosine kinase activity	MF	0.172	0.000172	0.00308	2.51	0.0024	Epha8/Kdr/Ddr2/Nrp1/Tek/Flt3/Kit/Epha3/Tie1/Epha7	10
GO:0030159	signaling receptor complex adaptor activity	MF	0.211	0.000183	0.0032	2.49	0.00249	Lrrk2/Shank2/Akap12/Sh2b2/Magi2/Gnb5/Lat/Gnb4	8
GO:0003774	cytoskeletal motor activity	MF	0.132	0.00019	0.00328	2.48	0.00254	Myo16/Kif7/Myo5a/Dnah5/Kif1a/Myo9a/Kif6/Dync2h1/Myl3/Myo1f/Dnah7b/Stard9/Dnah1/Kif16b	14
GO:0005267	potassium channel activity	MF	0.124	0.000233	0.0039	2.41	0.00303	Kcnk3/Kcnb2/Kcnj3/Grik1/Kcna6/Kcnd2/Kcnd3/Kcnq5/Grik2/Kcnma1/Kcnc4/Kcnip3/Kcng4/Pkd2/Kcnq4	15
GO:0008194	UDP-glycosyltransferase activity	MF	0.114	0.000254	0.00413	2.38	0.00321	B4galnt4/Gxylt2/Uggt2/B3galnt1/B4galt2/Has2/Galnt16/Lfng/Eogt/Ggta1/Galntl6/Poglut2/Mgat3/B3gnt5/Xylt1/Mfng/Large1	17
GO:0030215	semaphorin receptor binding	MF	0.273	0.000264	0.00417	2.38	0.00324	Sema5a/Sema5b/Sema7a/Sh3bp1/Sema3g/Sema6a	6
GO:0008235	metalloexopeptidase activity	MF	0.164	0.000265	0.00417	2.38	0.00324	Cpxm2/Mmp16/Enpep/Vash1/Cpe/Naalad2/Trhde/Agbl3/Lvrn/Vash2	10
GO:0022853	active ion transmembrane transporter activity	MF	0.0966	0.000285	0.00441	2.36	0.00342	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc8a1/Slc24a4/Slc9a7/Slc24a3/Slc8a3/Slc2a13/Slc6a15/Slc9a5/Slc23a2/Atp6v0e2/Slco4c1/Slc4a3/Slc38a1/Slc12a4/Cox4i2/Atp2b4/Atp1a2/Slc4a8	23
GO:0005249	voltage-gated potassium channel activity	MF	0.136	0.000398	0.00605	2.22	0.0047	Kcnk3/Kcnb2/Kcnj3/Kcna6/Kcnd2/Kcnd3/Kcnq5/Kcnma1/Kcnc4/Kcng4/Pkd2/Kcnq4	12
GO:0015491	cation:cation antiporter activity	MF	0.25	0.000443	0.00662	2.18	0.00514	Slc8a1/Slc24a4/Slc9a7/Slc24a3/Slc8a3/Slc9a5	6
GO:0005525	GTP binding	MF	0.0836	0.000478	0.00702	2.15	0.00546	Rragb/Agap2/Rasl12/Rab36/Gimap4/Gnai1/Arl6/Lrrk2/Gucy1b1/Gimap8/Rab34/Rragd/Dnajc27/Gucy1a1/Gimap6/Cracr2a/Tubb4a/Septin3/Rhobtb3/Nin/Arl3/Rasd2/Gnaz/Rrad/Septin4/Gimap5/Rab23/Gimap3/Rab39b/Rab27a	30
GO:0098632	cell-cell adhesion mediator activity	MF	0.206	0.000534	0.00773	2.11	0.006	Prtg/Lrrc4c/Jam3/Esam/Nfasc/Cd200/Ntng1	7
GO:0022804	active transmembrane transporter activity	MF	0.0808	0.000563	0.0079	2.1	0.00614	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc8a1/Slc24a4/Slc9a7/Abcg2/Slc24a3/Slc36a4/Slc8a3/Slc2a13/Slc6a15/Slc9a5/Slc23a2/Atp6v0e2/Abca5/Slco4c1/Abcg1/Abca8b/Slc4a3/Slc38a1/Slc12a4/Cox4i2/Abcd2/Atp2b4/Atp1a2/Abcb1a/Abcc5/Abcg3/Slc4a8	32
GO:0015368	calcium:cation antiporter activity	MF	0.4	0.000591	0.00803	2.1	0.00624	Slc8a1/Slc24a4/Slc24a3/Slc8a3	4
GO:0035374	chondroitin sulfate binding	MF	0.4	0.000591	0.00803	2.1	0.00624	Mdk/Rtn4rl1/Dpysl3/Ptn	4
GO:0008559	ABC-type xenobiotic transporter activity	MF	0.294	0.000599	0.00803	2.1	0.00624	Abcg2/Abca8b/Abcb1a/Abcc5/Abcg3	5
GO:0019001	guanyl nucleotide binding	MF	0.0812	0.000635	0.00827	2.08	0.00643	Rragb/Agap2/Rasl12/Rab36/Gimap4/Gnai1/Arl6/Lrrk2/Gucy1b1/Gimap8/Rab34/Rragd/Dnajc27/Gucy1a1/Gimap6/Cracr2a/Tubb4a/Septin3/Rhobtb3/Nin/Arl3/Rasd2/Pde5a/Gnaz/Rrad/Septin4/Gimap5/Rab23/Gimap3/Rab39b/Rab27a	31
GO:0032561	guanyl ribonucleotide binding	MF	0.0812	0.000635	0.00827	2.08	0.00643	Rragb/Agap2/Rasl12/Rab36/Gimap4/Gnai1/Arl6/Lrrk2/Gucy1b1/Gimap8/Rab34/Rragd/Dnajc27/Gucy1a1/Gimap6/Cracr2a/Tubb4a/Septin3/Rhobtb3/Nin/Arl3/Rasd2/Pde5a/Gnaz/Rrad/Septin4/Gimap5/Rab23/Gimap3/Rab39b/Rab27a	31
GO:0004181	metallocarboxypeptidase activity	MF	0.231	0.000704	0.00904	2.04	0.00702	Cpxm2/Vash1/Cpe/Naalad2/Agbl3/Vash2	6
GO:0015631	tubulin binding	MF	0.0803	0.000754	0.00945	2.02	0.00734	Gli1/Map2/Fez1/Capn6/Ccdc88a/Kif7/Lrrk2/Kif26a/Kif1a/Ndn/Reep1/Eml1/Rp1/Map9/Kif6/Katnal1/Dclk2/Nin/Arl3/Dysf/Cnn3/Fyn/Unc5c/Stard9/Tbcel/Brsk1/Mapre2/Vash2/Tppp/Kif16b/Map7d3	31
GO:0015276	ligand-gated ion channel activity	MF	0.111	0.000756	0.00945	2.02	0.00734	Kcnj3/Grid1/Gria4/Grik1/Ryr1/P2rx2/Rasa3/Grin2b/Glrb/Gabra4/Grik2/Kcnma1/Ryr3/Pkd2/Clca2	15
GO:0004970	ionotropic glutamate receptor activity	MF	0.278	8e-04	0.00986	2.01	0.00766	Grid1/Gria4/Grik1/Grin2b/Grik2	5
GO:0022834	ligand-gated channel activity	MF	0.109	0.000881	0.0105	1.98	0.00812	Kcnj3/Grid1/Gria4/Grik1/Ryr1/P2rx2/Rasa3/Grin2b/Glrb/Gabra4/Grik2/Kcnma1/Ryr3/Pkd2/Clca2	15
GO:0008331	high voltage-gated calcium channel activity	MF	0.364	0.000897	0.0105	1.98	0.00812	Cacna1c/Cacna1e/Cacna1a/Cacnb4	4
GO:0042285	xylosyltransferase activity	MF	0.364	0.000897	0.0105	1.98	0.00812	Gxylt2/Poglut2/Xylt1/Large1	4
GO:0005543	phospholipid binding	MF	0.0763	0.000906	0.0105	1.98	0.00812	Apob/Gap43/Nme4/Pla2g10/Nr5a2/Mark1/Syt13/Cpne5/Ccdc88a/P2rx2/Fermt2/Dab1/Pfn2/Lpar4/Cibar1/Plcb1/Rps6kc1/Thy1/Pltp/Mme/Cadps/Nrgn/Apoe/Syt7/Scin/Hip1/Arap3/Bin1/Dysf/Epdr1/Pard3b/Plcb2/Zfyve9/Cavin2/Kif16b	35
GO:0003924	GTPase activity	MF	0.085	0.00106	0.012	1.92	0.00935	Rragb/Agap2/Rasl12/Rab36/Gnai1/Arl6/Lrrk2/Rab34/Rragd/Dnajc27/Cracr2a/Tubb4a/Gng2/Septin3/Rhobtb3/Arl3/Rasd2/Gnaz/Rrad/Septin4/Rab23/Rab39b/Rab27a/Gnb4/Tppp	25
GO:0140359	ABC-type transporter activity	MF	0.214	0.00107	0.012	1.92	0.00935	Abcg2/Abcg1/Abca8b/Abcb1a/Abcc5/Abcg3	6
GO:0015298	solute:cation antiporter activity	MF	0.207	0.0013	0.014	1.86	0.0108	Slc8a1/Slc24a4/Slc9a7/Slc24a3/Slc8a3/Slc9a5	6
GO:0045499	chemorepellent activity	MF	0.207	0.0013	0.014	1.86	0.0108	Sema5a/Sema5b/Sema7a/Sema3g/Epha7/Sema6a	6
GO:0031402	sodium ion binding	MF	0.333	0.0013	0.014	1.86	0.0108	Scn1a/Scn2a/Scn3a/Atp1a2	4
GO:0099186	structural constituent of postsynapse	MF	0.25	0.00135	0.0143	1.85	0.0111	Shank2/Dlg2/Magi2/Mpp2/Dlg4	5
GO:0005251	delayed rectifier potassium channel activity	MF	0.2	0.00157	0.0162	1.79	0.0126	Kcnb2/Kcna6/Kcnq5/Kcnc4/Kcng4/Kcnq4	6
GO:0019199	transmembrane receptor protein kinase activity	MF	0.132	0.00157	0.0162	1.79	0.0126	Epha8/Kdr/Ddr2/Nrp1/Tek/Flt3/Kit/Epha3/Tie1/Epha7	10
GO:0003777	microtubule motor activity	MF	0.141	0.00166	0.017	1.77	0.0132	Kif7/Dnah5/Kif1a/Kif6/Dync2h1/Dnah7b/Stard9/Dnah1/Kif16b	9
GO:0008017	microtubule binding	MF	0.0849	0.00169	0.0171	1.77	0.0133	Gli1/Map2/Capn6/Ccdc88a/Kif7/Kif26a/Kif1a/Reep1/Eml1/Rp1/Map9/Kif6/Katnal1/Dclk2/Nin/Arl3/Dysf/Cnn3/Stard9/Mapre2/Vash2/Kif16b/Map7d3	23
GO:0051020	GTPase binding	MF	0.081	0.00171	0.0172	1.77	0.0133	Rragb/Rims3/Rasgrp3/Lrrk2/Myo5a/Gga2/Mical1/Ranbp17/Dock2/Rab34/Dock10/Rragd/Abi2/Dmxl2/Rasip1/Daam2/Dennd5a/Adcyap1r1/Rhobtb3/Bin1/Net1/Fgd1/Cdc42ep5/Cav1/Cyfip2/Kif16b	26
GO:0023026	MHC class II protein complex binding	MF	0.308	0.00181	0.018	1.75	0.014	H2-Ab1/H2-Ob/H2-Eb1/H2-Aa	4
GO:0030276	clathrin binding	MF	0.138	0.00185	0.018	1.74	0.014	Nsg2/Syt13/Lrrk2/Ap1m1/Trpc6/Syt7/Hip1/Nsg1/Arrb1	9
GO:0016758	hexosyltransferase activity	MF	0.0933	0.00186	0.018	1.74	0.014	B4galnt4/Uggt2/Pygm/Tmtc1/B3galnt1/B4galt2/Fut10/Has2/Galnt16/Lfng/Eogt/Ggta1/Galntl6/Poglut2/Mgat3/B3gnt5/Mfng/Large1	18
GO:0030165	PDZ domain binding	MF	0.108	0.00208	0.02	1.7	0.0155	Mpp3/Nlgn1/Nkd1/Lrp2/Dlg2/Sntb1/Lin7a/Grik2/Erc2/Mpp2/Fzd2/Dlg4/Atp2b4	13
GO:0030674	protein-macromolecule adaptor activity	MF	0.0798	0.00212	0.0202	1.7	0.0157	Epb41l3/Aph1b/Stx1b/Lrrk2/Ap1m1/Shank2/Akap12/Mapk8ip1/Klhdc2/Cntln/Ank2/Sh2b2/Abi2/Spsb4/Magi2/Hip1/Arrb1/Sarm1/Syne3/Frmd4a/Afap1l2/Gnb5/Lat/Gnb4/Cav1/Stx2	26
GO:0015248	sterol transporter activity	MF	0.188	0.00222	0.0209	1.68	0.0162	Apob/Osbp2/Pltp/Apoe/Abcg1/Osbpl1a	6
GO:0019842	vitamin binding	MF	0.103	0.00232	0.0216	1.67	0.0168	Stra6/P3h3/Abat/P4htm/Cbs/Pygm/Rbp7/Sptlc3/Kyat1/Hdc/Dhtkd1/Cth/P3h1/S100g	14
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	MF	0.145	0.00238	0.0219	1.66	0.017	Grid1/Gria4/Grik1/Grin2b/Glrb/Gabra4/Grik2/Gabbr1	8
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	MF	0.286	0.00245	0.0224	1.65	0.0174	Fads2/Fads1/Fads3/Degs2	4
GO:0015294	solute:cation symporter activity	MF	0.116	0.00265	0.0239	1.62	0.0186	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc2a13/Slc6a15/Slc23a2/Slc38a1/Slc12a4/Slc4a8	11
GO:0098960	postsynaptic neurotransmitter receptor activity	MF	0.13	0.00281	0.0251	1.6	0.0195	Grid1/Gria4/Grik1/Drd4/Grin2b/Glrb/Gabra4/Grik2/Gabbr1	9
GO:0008514	organic anion transmembrane transporter activity	MF	0.0919	0.00286	0.0252	1.6	0.0196	Slc1a3/Grik1/Slc13a5/Slc2a3/Slc7a2/Abcg2/Slc36a4/Slc29a1/Slc23a2/Sfxn5/Slco4c1/Slc4a3/Slc38a1/Slc25a23/Abcc5/Abcg3/Slc4a8	17
GO:0008238	exopeptidase activity	MF	0.115	0.00288	0.0252	1.6	0.0196	Cpxm2/Mmp16/Enpep/Vash1/Cpe/Naalad2/Mme/Trhde/Agbl3/Lvrn/Vash2	11
GO:0005540	hyaluronic acid binding	MF	0.208	0.0032	0.0259	1.59	0.0201	Cd44/Layn/Tnfaip6/Hapln3/Habp4	5
GO:0031681	G-protein beta-subunit binding	MF	0.208	0.0032	0.0259	1.59	0.0201	Gngt2/Gng11/Gng2/Rasd2/Gng7	5
GO:0031690	adrenergic receptor binding	MF	0.208	0.0032	0.0259	1.59	0.0201	Magi2/Bdkrb2/Arrb1/Arrb2/Dlg4	5
GO:0099604	ligand-gated calcium channel activity	MF	0.208	0.0032	0.0259	1.59	0.0201	Ryr1/Rasa3/Grin2b/Ryr3/Pkd2	5
GO:0031267	small GTPase binding	MF	0.0807	0.0032	0.0259	1.59	0.0201	Rims3/Rasgrp3/Lrrk2/Myo5a/Gga2/Mical1/Ranbp17/Dock2/Rab34/Dock10/Abi2/Dmxl2/Rasip1/Daam2/Dennd5a/Adcyap1r1/Rhobtb3/Net1/Fgd1/Cdc42ep5/Cav1/Cyfip2/Kif16b	23
GO:0005229	intracellular calcium activated chloride channel activity	MF	0.267	0.00323	0.0259	1.59	0.0201	Ano1/Ano2/Ttyh2/Clca2	4
GO:0015278	calcium-release channel activity	MF	0.267	0.00323	0.0259	1.59	0.0201	Ryr1/Rasa3/Ryr3/Pkd2	4
GO:0022821	potassium ion antiporter activity	MF	0.267	0.00323	0.0259	1.59	0.0201	Slc24a4/Slc9a7/Slc24a3/Slc9a5	4
GO:0042043	neurexin family protein binding	MF	0.267	0.00323	0.0259	1.59	0.0201	Nlgn1/Cpe/Nlgn3/Dlg4	4
GO:0061778	intracellular chloride channel activity	MF	0.267	0.00323	0.0259	1.59	0.0201	Ano1/Ano2/Ttyh2/Clca2	4
GO:0015293	symporter activity	MF	0.0979	0.00368	0.0289	1.54	0.0225	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc24a4/Slc24a3/Slc36a4/Slc2a13/Slc6a15/Slc23a2/Slc38a1/Slc12a4/Slc4a8	14
GO:0019955	cytokine binding	MF	0.0979	0.00368	0.0289	1.54	0.0225	Itga4/Cd109/Nog/Cd44/Il11ra1/Cxcr3/Kit/Il27ra/Tsku/Ltbp3/Nrros/Xcr1/Il12rb1/Il2rg	14
GO:0050780	dopamine receptor binding	MF	0.2	0.00386	0.0301	1.52	0.0234	Grin2b/Agtr1a/Arrb2/Dlg4/Palm	5
GO:0050660	flavin adenine dinucleotide binding	MF	0.116	0.00395	0.0305	1.52	0.0237	Gulo/Maob/Nos3/Mical1/Maoa/Fmo1/Aifm2/Dpyd/Steap4/Aox4	10
GO:0005172	vascular endothelial growth factor receptor binding	MF	0.25	0.00416	0.0316	1.5	0.0246	Angpt1/Ccdc88a/Cdh5/Vegfc	4
GO:0015562	efflux transmembrane transporter activity	MF	0.25	0.00416	0.0316	1.5	0.0246	Abcg2/Abcb1a/Abcc5/Abcg3	4
GO:0015291	secondary active transmembrane transporter activity	MF	0.0826	0.00441	0.0331	1.48	0.0257	Slc1a3/Slc6a2/Slc5a11/Slc13a5/Slc12a8/Slc8a1/Slc24a4/Slc9a7/Slc24a3/Slc36a4/Slc8a3/Slc2a13/Slc6a15/Slc9a5/Slc23a2/Slco4c1/Slc4a3/Slc38a1/Slc12a4/Slc4a8	20
GO:0008528	G protein-coupled peptide receptor activity	MF	0.0959	0.00443	0.0331	1.48	0.0257	Vipr2/Npr3/Ednrb/Cxcr3/Pth1r/Aplnr/Agtr1a/Ednra/Adcyap1r1/Bdkrb2/Ogfrl1/Xcr1/Calcrl/Prokr1	14
GO:0042626	ATPase-coupled transmembrane transporter activity	MF	0.108	0.0046	0.0339	1.47	0.0263	Abcg2/Atp6v0e2/Abca5/Abcg1/Abca8b/Abcd2/Atp2b4/Atp1a2/Abcb1a/Abcc5/Abcg3	11
GO:0008066	glutamate receptor activity	MF	0.192	0.00461	0.0339	1.47	0.0263	Grid1/Gria4/Grik1/Grin2b/Grik2	5
GO:0008083	growth factor activity	MF	0.0946	0.005	0.0365	1.44	0.0283	Hgf/Mdk/Igf1/Areg/Cxcl12/Gdf11/Gdf7/Jag2/Gdf10/Vegfc/Igf2/Kitl/Ccn2/Ptn	14
GO:0000149	SNARE binding	MF	0.101	0.00544	0.0389	1.41	0.0302	Syt13/Stx1b/Lrrk2/Myo5a/Exoc3l/Stxbp4/Syt7/Prrt2/Txlnb/Cav1/Stx2/Cacna1a	12
GO:0003785	actin monomer binding	MF	0.185	0.00546	0.0389	1.41	0.0302	Nos3/Pfn2/Coro1a/Myl3/Pknox2	5
GO:0090482	vitamin transmembrane transporter activity	MF	0.185	0.00546	0.0389	1.41	0.0302	Stra6/Slc2a3/Abcg2/Slc23a2/Abcg3	5
GO:0005496	steroid binding	MF	0.0984	0.00662	0.0464	1.33	0.0361	Cyp3a59/Ar/Cyp3a25/Igf1/Soat1/Osbp2/Ptch1/Gstm1/Atp1a2/Osbpl1a/Sidt1/S100g	12
GO:0001653	peptide receptor activity	MF	0.0915	0.00668	0.0464	1.33	0.0361	Vipr2/Npr3/Ednrb/Cxcr3/Pth1r/Aplnr/Agtr1a/Ednra/Adcyap1r1/Bdkrb2/Ogfrl1/Xcr1/Calcrl/Prokr1	14
GO:0030170	pyridoxal phosphate binding	MF	0.135	0.00677	0.0464	1.33	0.0361	Abat/Cbs/Pygm/Sptlc3/Kyat1/Hdc/Cth	7
GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	MF	0.135	0.00677	0.0464	1.33	0.0361	Grid1/Gria4/Grik1/Grin2b/Glrb/Gabra4/Grik2	7

Visualisation

bp_dot[[2]]

mf_dot[[2]]

cc_dot[[2]]

upset[[2]]

# display the top 30 most sig
enrichGO_sig[[3]] %>% 
  dplyr::mutate_if(is.numeric, funs(as.character(signif(.,3)))) %>% 
  kable(caption = "Significantly enriched GO terms") %>%
  kable_styling(bootstrap_options = c("striped", "hover")) %>%
  scroll_box(height = "600px")

Significantly enriched GO terms
	Description	ontology	GeneRatio	pvalue	p.adjust	logFDR	qvalue	geneID	Count
GO:0048754	branching morphogenesis of an epithelial tube	BP	0.115	1.62e-16	5.72e-13	12.2	4.09e-13	Ihh/Wnt6/Sfrp2/Hhip/Lef1/Angpt1/Sema5a/Mdk/Nog/Tbx2/Hoxd11/Adamts16/Igf1/Areg/Npnt/Kdr/Gpc3/Hoxa11/Foxf1/Cd44/Cxcl12/Gdf7	22
GO:0061138	morphogenesis of a branching epithelium	BP	0.1	6.73e-16	1.19e-12	11.9	8.49e-13	Ihh/Hgf/Wnt6/Sfrp2/Hhip/Lef1/Angpt1/Sema5a/Mdk/Nog/Tbx2/Hoxd11/Adamts16/Igf1/Areg/Npnt/Kdr/Gpc3/Hoxa11/Foxf1/Cd44/Cxcl12/Gdf7	23
GO:0030198	extracellular matrix organization	BP	0.0762	6.91e-14	4.67e-11	10.3	3.34e-11	Cyp1b1/Ihh/Col11a1/Hmcn1/Vit/Mmp16/Sfrp2/Sema5a/Adamts20/Col14a1/Col4a6/Adamts16/Scara3/Npnt/Spock2/Prdm5/Tgfbi/Foxf1/Has2/Col9a2/Olfml2b/Adamts19/Mmp2/Nid1	24
GO:0043062	extracellular structure organization	BP	0.0759	7.41e-14	4.67e-11	10.3	3.34e-11	Cyp1b1/Ihh/Col11a1/Hmcn1/Vit/Mmp16/Sfrp2/Sema5a/Adamts20/Col14a1/Col4a6/Adamts16/Scara3/Npnt/Spock2/Prdm5/Tgfbi/Foxf1/Has2/Col9a2/Olfml2b/Adamts19/Mmp2/Nid1	24
GO:0045229	external encapsulating structure organization	BP	0.0757	7.94e-14	4.67e-11	10.3	3.34e-11	Cyp1b1/Ihh/Col11a1/Hmcn1/Vit/Mmp16/Sfrp2/Sema5a/Adamts20/Col14a1/Col4a6/Adamts16/Scara3/Npnt/Spock2/Prdm5/Tgfbi/Foxf1/Has2/Col9a2/Olfml2b/Adamts19/Mmp2/Nid1	24
GO:0097485	neuron projection guidance	BP	0.0734	5.71e-11	2.52e-08	7.6	1.8e-08	Gap43/Epha8/Prtg/Efnb3/Pla2g10/Sema5a/Dcc/Nog/Sema5b/Ptpro/Rnf165/Plxnb1/Dpysl4/Edn3/Lrp2/Evl/Sema7a/Cxcl12/Gdf7	19
GO:0060562	epithelial tube morphogenesis	BP	0.0582	5.71e-11	2.52e-08	7.6	1.8e-08	Ihh/Wnt6/Sfrp2/Hhip/Lef1/Angpt1/Sema5a/Mdk/Nog/Tbx2/Hoxd11/Adamts16/Igf1/Areg/Npnt/Kdr/Gpc3/Hoxa11/Foxf1/Cd44/Lrp2/Cxcl12/Gdf7	23
GO:0007409	axonogenesis	BP	0.0507	1.54e-10	6.03e-08	7.22	4.31e-08	Gap43/Epha8/Ptprz1/Prtg/Efnb3/Map2/Pla2g10/Sema5a/Dcc/Nog/Lrrc4c/Sema5b/Ptpro/Rnf165/Itga4/Plxnb1/Nptx1/Cdh2/Dab1/Edn3/Lrp2/Evl/Sema7a/Cxcl12/Gdf7	25
GO:0007411	axon guidance	BP	0.0698	4.17e-10	1.47e-07	6.83	1.05e-07	Gap43/Epha8/Prtg/Efnb3/Pla2g10/Sema5a/Dcc/Nog/Sema5b/Ptpro/Rnf165/Plxnb1/Edn3/Lrp2/Evl/Sema7a/Cxcl12/Gdf7	18
GO:0035107	appendage morphogenesis	BP	0.0862	6.71e-10	1.97e-07	6.71	1.41e-07	Ihh/Sfrp2/Lef1/Aff3/Nog/Pkdcc/Hoxd10/Tbx2/Hoxd11/Rnf165/Gpc3/Hoxa11/Hoxa10/Osr2/Hoxd9	15
GO:0035108	limb morphogenesis	BP	0.0862	6.71e-10	1.97e-07	6.71	1.41e-07	Ihh/Sfrp2/Lef1/Aff3/Nog/Pkdcc/Hoxd10/Tbx2/Hoxd11/Rnf165/Gpc3/Hoxa11/Hoxa10/Osr2/Hoxd9	15
GO:0001655	urogenital system development	BP	0.0543	1.42e-09	3.68e-07	6.43	2.63e-07	Stra6/Wnt6/Wnt11/Angpt1/Nog/Hoxd11/Adamts16/Igf1/Ptpro/Cyp7b1/Npnt/Pygo1/Ednrb/Gpc3/Hoxa11/Foxf1/Cd44/Osr2/Lrp2/Mmp2/Nid1	21
GO:0098742	cell-cell adhesion via plasma-membrane adhesion molecules	BP	0.0748	1.46e-09	3.68e-07	6.43	2.63e-07	Gpc6/Prtg/Hmcn1/Sdk2/Pcdh18/Lrrc4c/Mcam/Nlgn1/Ptprd/Itga4/Lrrc4b/Cdh6/Cdh2/Dab1/Tenm3/Cdh10	16
GO:0050673	epithelial cell proliferation	BP	0.0483	2.15e-09	5.07e-07	6.3	3.62e-07	Gli1/Ihh/Hgf/Sfrp2/Sema5a/Cd109/Mdk/Nog/Tbx2/Gkn3/Igf1/Fst/Areg/Itga4/Cyp7b1/Kdr/Ednrb/Gpc3/Calca/Osr2/Has2/Cxcl12/Agap2	23
GO:0030326	embryonic limb morphogenesis	BP	0.0909	4.91e-09	1.02e-06	5.99	7.29e-07	Ihh/Sfrp2/Lef1/Aff3/Nog/Hoxd10/Tbx2/Hoxd11/Gpc3/Hoxa11/Hoxa10/Osr2/Hoxd9	13
GO:0035113	embryonic appendage morphogenesis	BP	0.0909	4.91e-09	1.02e-06	5.99	7.29e-07	Ihh/Sfrp2/Lef1/Aff3/Nog/Hoxd10/Tbx2/Hoxd11/Gpc3/Hoxa11/Hoxa10/Osr2/Hoxd9	13
GO:0048736	appendage development	BP	0.0735	6.01e-09	1.12e-06	5.95	7.99e-07	Ihh/Sfrp2/Lef1/Aff3/Nog/Pkdcc/Hoxd10/Tbx2/Hoxd11/Rnf165/Gpc3/Hoxa11/Hoxa10/Osr2/Hoxd9	15
GO:0060173	limb development	BP	0.0735	6.01e-09	1.12e-06	5.95	7.99e-07	Ihh/Sfrp2/Lef1/Aff3/Nog/Pkdcc/Hoxd10/Tbx2/Hoxd11/Rnf165/Gpc3/Hoxa11/Hoxa10/Osr2/Hoxd9	15
GO:0042391	regulation of membrane potential	BP	0.0469	8.32e-09	1.47e-06	5.83	1.05e-06	Kcnk3/Nalcn/Grik1/Kcnd2/Begain/Kcnd3/Rims3/Adra1a/Drd4/Scn4b/Nlgn1/Slc24a4/Scn1a/Abat/Kdr/Celf4/P2rx2/Grin2b/Ano1/Bok/Slc8a3/Gabra4	22
GO:0001569	branching involved in blood vessel morphogenesis	BP	0.178	2.32e-08	3.81e-06	5.42	2.73e-06	Ihh/Sfrp2/Lef1/Angpt1/Sema5a/Mdk/Kdr/Cxcl12	8
GO:0031644	regulation of nervous system process	BP	0.0722	2.46e-08	3.81e-06	5.42	2.73e-06	Hgf/Begain/Drd4/Igf1/Nlgn1/Nptx1/Abat/Ednrb/Celf4/Calca/Nos3/Grin2b/Wasf3/Slc8a3	14
GO:0048705	skeletal system morphogenesis	BP	0.0613	2.48e-08	3.81e-06	5.42	2.73e-06	Ihh/Col11a1/Mmp16/Sfrp2/Hhip/Nog/Hoxd10/Hoxd11/Hoxa11/Stc1/Cbs/Osr2/Has2/Hoxd9/Frem1/Mmp2	16
GO:0009581	detection of external stimulus	BP	0.0876	2.93e-08	4.31e-06	5.37	3.08e-06	Col11a1/Sema5a/Sema5b/Igf1/Slc24a4/Scn1a/Calca/Foxf1/Grin2b/Serpine2/Ano1/Cxcl12	12
GO:0072001	renal system development	BP	0.0522	3.97e-08	5.38e-06	5.27	3.85e-06	Stra6/Wnt6/Wnt11/Angpt1/Nog/Hoxd11/Adamts16/Ptpro/Npnt/Pygo1/Ednrb/Gpc3/Hoxa11/Foxf1/Cd44/Osr2/Lrp2/Nid1	18
GO:0003012	muscle system process	BP	0.0465	4.63e-08	6.06e-06	5.22	4.33e-06	Kcnd3/Ryr1/Col14a1/Sgcd/Adra1a/Tbx2/Scn4b/Igf1/Scn1a/Npnt/Mybpc1/Abat/Ednrb/Tmod2/Stc1/Calca/Nos3/Edn3/P2rx2/Slc8a3	20
GO:0006936	muscle contraction	BP	0.0541	5.58e-08	7.03e-06	5.15	5.03e-06	Kcnd3/Ryr1/Sgcd/Adra1a/Tbx2/Scn4b/Scn1a/Npnt/Mybpc1/Abat/Ednrb/Tmod2/Stc1/Calca/Edn3/P2rx2/Slc8a3	17
GO:0001822	kidney development	BP	0.0515	1.14e-07	1.34e-05	4.87	9.59e-06	Stra6/Wnt6/Wnt11/Angpt1/Nog/Hoxd11/Adamts16/Ptpro/Npnt/Pygo1/Ednrb/Gpc3/Hoxa11/Cd44/Osr2/Lrp2/Nid1	17
GO:0072006	nephron development	BP	0.0764	1.33e-07	1.5e-05	4.82	1.07e-05	Wnt6/Angpt1/Nog/Hoxd11/Adamts16/Ptpro/Npnt/Ednrb/Gpc3/Hoxa11/Cd44/Nid1	12
GO:0060348	bone development	BP	0.0581	1.36e-07	1.5e-05	4.82	1.07e-05	Ihh/Mmp16/Sfrp2/Ryr1/Hoxd11/Igf1/Plxnb1/Kdr/Evc/Hoxa11/Stc1/Cbs/Osr2/Has2/Frem1	15
GO:0007224	smoothened signaling pathway	BP	0.0755	1.53e-07	1.63e-05	4.79	1.17e-05	Gli1/Ihh/Hhip/Ptch2/Nog/Evc2/Evc/Gpc3/Foxf1/Serpine2/Dzip1l/Kif7	12
GO:0060485	mesenchyme development	BP	0.0535	1.62e-07	1.68e-05	4.78	1.2e-05	Sfrp2/Wnt11/Lef1/Sema5a/Mdk/Nog/Sema5b/Tbx2/Itga4/Ednrb/Cdh2/Foxf1/Nos3/Edn3/Has2/Sema7a	16
GO:0048265	response to pain	BP	0.175	2.01e-07	2.02e-05	4.69	1.45e-05	Grik1/Slc6a2/Ednrb/Calca/P2rx2/Cacna1e/Grin2b	7
GO:0060541	respiratory system development	BP	0.0562	2.12e-07	2.08e-05	4.68	1.49e-05	Gli1/Stra6/Hhip/Lef1/Nog/Pkdcc/Tbx2/Igf1/Kdr/Gpc3/Edaradd/Foxf1/Nos3/Hopx/Ano1	15
GO:0009582	detection of abiotic stimulus	BP	0.0809	2.51e-07	2.33e-05	4.63	1.67e-05	Col11a1/Sema5a/Sema5b/Igf1/Slc24a4/Scn1a/Calca/Grin2b/Serpine2/Ano1/Cxcl12	11
GO:0045785	positive regulation of cell adhesion	BP	0.0415	2.9e-07	2.63e-05	4.58	1.88e-05	Ihh/Efnb3/Vit/Col26a1/Lef1/Angpt1/Cd83/Mdk/Igf1/Itga4/Npnt/Kdr/Spock2/Chst2/Calca/Foxf1/Cd44/Has2/Cxcl12/Nid1	20
GO:0060349	bone morphogenesis	BP	0.0909	2.98e-07	2.63e-05	4.58	1.88e-05	Ihh/Mmp16/Sfrp2/Hoxd11/Hoxa11/Stc1/Cbs/Osr2/Has2/Frem1	10
GO:0048608	reproductive structure development	BP	0.0413	3.1e-07	2.67e-05	4.57	1.91e-05	Ndp/Tex15/Stra6/Sfrp2/Lef1/Angpt1/Nog/Igf1/Fst/Itga4/Cyp7b1/Kdr/Hoxa11/Hoxa10/Nos3/Cd44/Lrp2/Serpine2/Mmp2/Gdf7	20
GO:0061458	reproductive system development	BP	0.041	3.53e-07	2.96e-05	4.53	2.12e-05	Ndp/Tex15/Stra6/Sfrp2/Lef1/Angpt1/Nog/Igf1/Fst/Itga4/Cyp7b1/Kdr/Hoxa11/Hoxa10/Nos3/Cd44/Lrp2/Serpine2/Mmp2/Gdf7	20
GO:0071805	potassium ion transmembrane transport	BP	0.0631	3.7e-07	3.04e-05	4.52	2.17e-05	Kcnk3/Kcnb2/Nalcn/Kcnj3/Slc1a3/Kcnd2/Kcna6/Kcnd3/Slc24a4/Slc12a8/Edn3/Kcnq5/Slc9a7	13
GO:0006813	potassium ion transport	BP	0.0576	3.99e-07	3.2e-05	4.49	2.29e-05	Kcnk3/Kcnb2/Nalcn/Kcnj3/Slc1a3/Kcnd2/Kcna6/Kcnd3/Slc24a4/Slc12a8/Nos3/Edn3/Kcnq5/Slc9a7	14
GO:0050678	regulation of epithelial cell proliferation	BP	0.0444	4.29e-07	3.36e-05	4.47	2.4e-05	Gli1/Ihh/Sfrp2/Sema5a/Cd109/Mdk/Nog/Gkn3/Igf1/Itga4/Cyp7b1/Kdr/Ednrb/Gpc3/Osr2/Has2/Cxcl12/Agap2	18
GO:0006814	sodium ion transport	BP	0.0565	5.1e-07	3.83e-05	4.42	2.74e-05	Nalcn/Slc5a11/Slc13a5/Slc6a2/Drd4/Scn4b/Slc24a4/Scn1a/Ednrb/Hecw2/Nos3/Slc9a7/Serpine2/Slc8a3	14
GO:0009612	response to mechanical stimulus	BP	0.0674	5.17e-07	3.83e-05	4.42	2.74e-05	Stra6/Col11a1/Slc1a3/Wnt11/Mdk/Igf1/Scn1a/Nos3/Grin2b/Serpine2/Mmp2/Cxcl12	12
GO:0072498	embryonic skeletal joint development	BP	0.312	5.27e-07	3.83e-05	4.42	2.74e-05	Ihh/Nog/Hoxd11/Hoxa11/Osr2	5
GO:0072009	nephron epithelium development	BP	0.0855	5.32e-07	3.83e-05	4.42	2.74e-05	Wnt6/Nog/Hoxd11/Adamts16/Ptpro/Npnt/Ednrb/Gpc3/Hoxa11/Cd44	10
GO:0001658	branching involved in ureteric bud morphogenesis	BP	0.119	5.73e-07	4.04e-05	4.39	2.89e-05	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0001666	response to hypoxia	BP	0.0602	6.35e-07	4.4e-05	4.36	3.14e-05	Kcnk3/Kcnd2/Ryr1/Ddah1/Abat/Kdr/Pygm/Cbs/P2rx2/Grin2b/Tert/Slc8a3/Mmp2	13
GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	BP	0.14	9.82e-07	6.66e-05	4.18	4.76e-05	Hmcn1/Mcam/Nlgn1/Ptprd/Itga4/Cdh2/Tenm3	7
GO:0022612	gland morphogenesis	BP	0.0701	1.06e-06	7.05e-05	4.15	5.04e-05	Gli1/Hgf/Mdk/Nog/Tbx2/Igf1/Areg/Cyp7b1/Cd44/Mmp2/Gdf7	11
GO:0003073	regulation of systemic arterial blood pressure	BP	0.0787	1.14e-06	7.42e-05	4.13	5.3e-05	Adra1a/Adamts16/Ptpro/Ddah1/Kdr/Ednrb/Calca/Nos3/Edn3/P2rx2	10
GO:0060675	ureteric bud morphogenesis	BP	0.108	1.24e-06	7.96e-05	4.1	5.7e-05	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0042063	gliogenesis	BP	0.0457	1.31e-06	8.27e-05	4.08	5.91e-05	Gap43/Ptprz1/Lef1/Apcdd1/Mdk/Nog/Igf1/Lamc3/Areg/Cdh2/Dab1/Lrp2/Tert/Serpine2/Wasf3/Slc8a3	16
GO:0072171	mesonephric tubule morphogenesis	BP	0.107	1.38e-06	8.52e-05	4.07	6.1e-05	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0099068	postsynapse assembly	BP	0.176	1.46e-06	8.87e-05	4.05	6.34e-05	Gap43/Nlgn1/Ptprd/Nptx1/Lrrc4b/Cdh2	6
GO:0050808	synapse organization	BP	0.0385	1.78e-06	0.000106	3.97	7.61e-05	Gap43/Gpc6/Sdk2/St8sia2/Lrrc4c/Rims3/Ptpro/Nlgn1/Ptprd/Plxnb1/Pdzrn3/Nptx1/Lrrc4b/Cdh2/P2rx2/Ppfia2/Grin2b/Wasf3/Slc8a3	19
GO:0016055	Wnt signaling pathway	BP	0.0399	1.99e-06	0.000117	3.93	8.38e-05	Ndp/Gli1/Wnt6/Sfrp2/Wnt11/Lef1/Sema5a/Apcdd1/Mdk/Nog/Ptpro/Pygo1/Ednrb/Gpc3/Cdh2/Nkd1/Cd44/Tert	18
GO:0001667	ameboidal-type cell migration	BP	0.0398	2.06e-06	0.000118	3.93	8.41e-05	Cyp1b1/Wnt11/Angpt1/Sema5a/Sema5b/Igf1/Itga4/Kdr/Ednrb/Cdh2/Stc1/Calca/Nos3/Edn3/Has2/Evl/Sema7a/Cxcl12	18
GO:0098657	import into cell	BP	0.0542	2.07e-06	0.000118	3.93	8.41e-05	Kcnj3/Slc1a3/Slc6a2/Acsl6/Kcnd3/Slc24a4/Itga4/Slc12a8/Lrp2/Cacna1e/Slc9a7/Slc8a3/Slc7a2	13
GO:0198738	cell-cell signaling by wnt	BP	0.0397	2.12e-06	0.000119	3.93	8.49e-05	Ndp/Gli1/Wnt6/Sfrp2/Wnt11/Lef1/Sema5a/Apcdd1/Mdk/Nog/Ptpro/Pygo1/Ednrb/Gpc3/Cdh2/Nkd1/Cd44/Tert	18
GO:0060560	developmental growth involved in morphogenesis	BP	0.0498	2.24e-06	0.000122	3.91	8.76e-05	Sfrp2/Map2/Wnt11/Sema5a/St8sia2/Sema5b/Tbx2/Cpne5/Areg/Itga4/Nkd1/Edn3/Sema7a/Cxcl12	14
GO:0050767	regulation of neurogenesis	BP	0.0396	2.26e-06	0.000122	3.91	8.76e-05	Ptprz1/Prtg/Efnb3/Map2/Sema5a/Mdk/Nog/Sema5b/Igf1/Ptprd/Plxnb1/Kdr/Dab1/Lrp2/Sema7a/Tert/Serpine2/Cxcl12	18
GO:0036293	response to decreased oxygen levels	BP	0.0535	2.37e-06	0.000127	3.9	9.07e-05	Kcnk3/Kcnd2/Ryr1/Ddah1/Abat/Kdr/Pygm/Cbs/P2rx2/Grin2b/Tert/Slc8a3/Mmp2	13
GO:0009954	proximal/distal pattern formation	BP	0.162	2.45e-06	0.000129	3.89	9.22e-05	Gli1/Hoxd10/Hoxd11/Hoxa11/Hoxa10/Hoxd9	6
GO:0048844	artery morphogenesis	BP	0.0988	2.48e-06	0.000129	3.89	9.22e-05	Apob/Stra6/Wnt11/Mdk/Nog/Tbx2/Foxf1/Lrp2	8
GO:0001823	mesonephros development	BP	0.0818	2.85e-06	0.000146	3.84	0.000104	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44/Osr2	9
GO:0072078	nephron tubule morphogenesis	BP	0.0964	2.99e-06	0.000151	3.82	0.000108	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0072088	nephron epithelium morphogenesis	BP	0.0941	3.58e-06	0.000178	3.75	0.000127	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0050906	detection of stimulus involved in sensory perception	BP	0.0611	4.02e-06	0.000197	3.71	0.000141	Col11a1/Sema5a/Sema5b/Igf1/Slc24a4/Scn1a/Calca/Grin2b/Serpine2/Ano1/Cxcl12	11
GO:0050679	positive regulation of epithelial cell proliferation	BP	0.0553	4.13e-06	2e-04	3.7	0.000143	Ihh/Sema5a/Mdk/Nog/Igf1/Itga4/Cyp7b1/Kdr/Osr2/Has2/Cxcl12/Agap2	12
GO:0048732	gland development	BP	0.0378	4.22e-06	0.000201	3.7	0.000144	Gli1/Stra6/Hgf/Lef1/Mdk/Nog/Tbx2/Igf1/Areg/Cyp7b1/Edaradd/Foxf1/Cd44/Hoxd9/Serpine2/Mmp2/Gdf7/Agap2	18
GO:0072028	nephron morphogenesis	BP	0.092	4.27e-06	0.000201	3.7	0.000144	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0010171	body morphogenesis	BP	0.113	4.33e-06	0.000201	3.7	0.000144	Ihh/Stra6/Lef1/Nog/Crispld1/Gpc3/Mmp2	7
GO:0060840	artery development	BP	0.0776	4.43e-06	0.000203	3.69	0.000145	Apob/Stra6/Wnt11/Mdk/Nog/Tbx2/Foxf1/Lrp2/Kif7	9
GO:0008217	regulation of blood pressure	BP	0.0545	4.76e-06	0.000215	3.67	0.000154	Adra1a/Adamts16/Ptpro/Ddah1/Abat/Kdr/Ednrb/Calca/Nos3/Edn3/P2rx2/Npr3	12
GO:0061333	renal tubule morphogenesis	BP	0.0899	5.07e-06	0.000225	3.65	0.000161	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0060078	regulation of postsynaptic membrane potential	BP	0.0763	5.1e-06	0.000225	3.65	0.000161	Grik1/Begain/Drd4/Nlgn1/Abat/Celf4/Grin2b/Slc8a3/Gabra4	9
GO:0060070	canonical Wnt signaling pathway	BP	0.0461	5.56e-06	0.00024	3.62	0.000172	Gli1/Wnt6/Sfrp2/Wnt11/Lef1/Sema5a/Mdk/Nog/Ptpro/Pygo1/Ednrb/Gpc3/Cdh2/Nkd1	14
GO:0072073	kidney epithelium development	BP	0.0658	5.76e-06	0.00024	3.62	0.000172	Wnt6/Nog/Hoxd11/Adamts16/Ptpro/Npnt/Ednrb/Gpc3/Hoxa11/Cd44	10
GO:0071772	response to BMP	BP	0.0588	5.79e-06	0.00024	3.62	0.000172	Sfrp2/Lef1/Kcnd3/Nog/Fst/Rnf165/Kdr/Gpc3/Lrp2/Vstm2a/Gdf7	11
GO:0071773	cellular response to BMP stimulus	BP	0.0588	5.79e-06	0.00024	3.62	0.000172	Sfrp2/Lef1/Kcnd3/Nog/Fst/Rnf165/Kdr/Gpc3/Lrp2/Vstm2a/Gdf7	11
GO:0070444	oligodendrocyte progenitor proliferation	BP	0.333	5.85e-06	0.00024	3.62	0.000172	Ptprz1/Nog/Cdh2/Lrp2	4
GO:0070445	regulation of oligodendrocyte progenitor proliferation	BP	0.333	5.85e-06	0.00024	3.62	0.000172	Ptprz1/Nog/Cdh2/Lrp2	4
GO:0060537	muscle tissue development	BP	0.0365	6.83e-06	0.000277	3.56	0.000198	Gli1/Ihh/Stra6/Col11a1/Lef1/AW551984/Angpt1/Ryr1/Col14a1/Sgcd/Nog/Hoxd10/Adra1a/Tbx2/Igf1/P2rx2/Lrp2/Hoxd9	18
GO:0099084	postsynaptic specialization organization	BP	0.136	7e-06	0.000278	3.56	0.000199	Gap43/Nlgn1/Ptprd/Nptx1/Lrrc4b/Cdh2	6
GO:1904035	regulation of epithelial cell apoptotic process	BP	0.086	7.04e-06	0.000278	3.56	0.000199	Angpt1/Sema5a/Mdk/Igf1/Itga4/Kdr/Tert/Bok	8
GO:0098739	import across plasma membrane	BP	0.0576	7.09e-06	0.000278	3.56	0.000199	Kcnj3/Slc1a3/Acsl6/Kcnd3/Slc24a4/Slc12a8/Lrp2/Cacna1e/Slc9a7/Slc8a3/Slc7a2	11
GO:0007162	negative regulation of cell adhesion	BP	0.0447	7.75e-06	3e-04	3.52	0.000215	Cyp1b1/Ihh/Ptprz1/Lef1/Angpt1/Sema5a/Mdk/Plxnb1/Abat/Dab1/Cd44/Serpine2/Mmp2/Cxcl12	14
GO:0051962	positive regulation of nervous system development	BP	0.0418	8.33e-06	0.000318	3.5	0.000227	Ptprz1/Sema5a/St8sia2/Mdk/Nog/Igf1/Nlgn1/Ptprd/Plxnb1/Kdr/Lrrc4b/Lrp2/Sema7a/Serpine2/Cxcl12	15
GO:0060272	embryonic skeletal joint morphogenesis	BP	0.308	8.38e-06	0.000318	3.5	0.000227	Nog/Hoxd11/Hoxa11/Osr2	4
GO:0035136	forelimb morphogenesis	BP	0.13	9.12e-06	0.000339	3.47	0.000242	Hoxd10/Hoxd11/Rnf165/Hoxa11/Osr2/Hoxd9	6
GO:0060323	head morphogenesis	BP	0.13	9.12e-06	0.000339	3.47	0.000242	Ihh/Stra6/Lef1/Nog/Crispld1/Mmp2	6
GO:0030324	lung development	BP	0.0508	9.71e-06	0.000357	3.45	0.000255	Gli1/Stra6/Hhip/Nog/Pkdcc/Tbx2/Igf1/Kdr/Gpc3/Foxf1/Nos3/Hopx	12
GO:0050974	detection of mechanical stimulus involved in sensory perception	BP	0.128	1.04e-05	0.000376	3.42	0.000269	Col11a1/Igf1/Scn1a/Grin2b/Serpine2/Cxcl12	6
GO:0061351	neural precursor cell proliferation	BP	0.0553	1.05e-05	0.000376	3.42	0.000269	Gli1/Ptprz1/Hhip/Lef1/Acsl6/Mdk/Nog/Igf1/Cdh2/Lrp2/Smarca1	11
GO:0060047	heart contraction	BP	0.0504	1.06e-05	0.000377	3.42	0.000269	Kcnd3/Sgcd/Adra1a/Scn4b/Scn1a/Ednrb/Stc1/Calca/Nos3/Hopx/Edn3/Cacna1e	12
GO:0098698	postsynaptic specialization assembly	BP	0.179	1.07e-05	0.000377	3.42	0.00027	Gap43/Nlgn1/Ptprd/Nptx1/Lrrc4b	5
GO:0042733	embryonic digit morphogenesis	BP	0.0986	1.08e-05	0.000377	3.42	0.00027	Ihh/Sfrp2/Nog/Tbx2/Hoxd11/Hoxa11/Osr2	7
GO:0030323	respiratory tube development	BP	0.0502	1.1e-05	0.000381	3.42	0.000273	Gli1/Stra6/Hhip/Nog/Pkdcc/Tbx2/Igf1/Kdr/Gpc3/Foxf1/Nos3/Hopx	12
GO:0048762	mesenchymal cell differentiation	BP	0.0496	1.25e-05	0.000424	3.37	0.000303	Sfrp2/Wnt11/Lef1/Sema5a/Mdk/Nog/Sema5b/Ednrb/Cdh2/Edn3/Has2/Sema7a	12
GO:0030178	negative regulation of Wnt signaling pathway	BP	0.0599	1.32e-05	0.000443	3.35	0.000317	Gli1/Sfrp2/Wnt11/Apcdd1/Mdk/Nog/Ptpro/Gpc3/Cdh2/Nkd1	10
GO:2000027	regulation of animal organ morphogenesis	BP	0.0677	1.35e-05	0.000449	3.35	0.000321	Hgf/Sfrp2/Wnt11/Apcdd1/Nog/Hoxd11/Gpc3/Hoxa11/Nkd1	9
GO:0072080	nephron tubule development	BP	0.0784	1.4e-05	0.00046	3.34	0.000329	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0090090	negative regulation of canonical Wnt signaling pathway	BP	0.0672	1.43e-05	0.000468	3.33	0.000335	Gli1/Sfrp2/Wnt11/Mdk/Nog/Ptpro/Gpc3/Cdh2/Nkd1	9
GO:0010721	negative regulation of cell development	BP	0.0534	1.45e-05	0.000468	3.33	0.000335	Prtg/Efnb3/Map2/Sema5a/Nog/Sema5b/Igf1/Ednrb/Dab1/Sema7a/Tert	11
GO:0060993	kidney morphogenesis	BP	0.0777	1.5e-05	0.000477	3.32	0.000341	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0099565	chemical synaptic transmission, postsynaptic	BP	0.0777	1.5e-05	0.000477	3.32	0.000341	Grik1/Begain/Drd4/Nlgn1/Abat/Celf4/Grin2b/Slc8a3	8
GO:0010720	positive regulation of cell development	BP	0.0397	1.53e-05	0.000481	3.32	0.000344	Ptprz1/Sema5a/Mdk/Nog/Hoxd11/Igf1/Ptprd/Plxnb1/Kdr/Hoxa11/Has2/Lrp2/Sema7a/Serpine2/Cxcl12	15
GO:0048015	phosphatidylinositol-mediated signaling	BP	0.0588	1.54e-05	0.000481	3.32	0.000344	Hgf/Myo16/Angpt1/Car8/Igf1/Plxnb1/Kdr/Serpine2/Npr3/Agap2	10
GO:0048562	embryonic organ morphogenesis	BP	0.042	1.55e-05	0.000481	3.32	0.000344	Gli1/Ihh/Stra6/Col11a1/Mmp16/Wnt11/Nog/Hoxd10/Tbx2/Hoxd11/Hoxa11/Foxf1/Osr2/Hoxd9	14
GO:0003015	heart process	BP	0.048	1.73e-05	0.00053	3.28	0.000379	Kcnd3/Sgcd/Adra1a/Scn4b/Scn1a/Ednrb/Stc1/Calca/Nos3/Hopx/Edn3/Cacna1e	12
GO:0048017	inositol lipid-mediated signaling	BP	0.0578	1.79e-05	0.000545	3.26	0.00039	Hgf/Myo16/Angpt1/Car8/Igf1/Plxnb1/Kdr/Serpine2/Npr3/Agap2	10
GO:0003002	regionalization	BP	0.039	1.89e-05	0.000569	3.25	0.000407	Gli1/Sfrp2/Hhip/Wnt11/Lef1/Nog/Hoxd10/Hoxd11/Gpc3/Hoxa11/Foxf1/Hoxa10/Lrp2/Hoxd9/Dzip1l	15
GO:0061448	connective tissue development	BP	0.0441	1.91e-05	0.000569	3.25	0.000407	Ihh/Col11a1/Sfrp2/Mdk/Nog/Pkdcc/Hoxd11/Igf1/Hoxa11/Stc1/Cbs/Osr2/Gdf7	13
GO:0055123	digestive system development	BP	0.0647	1.92e-05	0.000569	3.25	0.000407	Ihh/Stra6/Sfrp2/Pkdcc/Tbx2/Igf1/Ednrb/Foxf1/Clmp	9
GO:0051216	cartilage development	BP	0.0516	1.97e-05	0.000569	3.25	0.000407	Ihh/Col11a1/Sfrp2/Mdk/Nog/Pkdcc/Hoxd11/Hoxa11/Stc1/Cbs/Osr2	11
GO:0001657	ureteric bud development	BP	0.0748	1.98e-05	0.000569	3.25	0.000407	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0072163	mesonephric epithelium development	BP	0.0748	1.98e-05	0.000569	3.25	0.000407	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0072164	mesonephric tubule development	BP	0.0748	1.98e-05	0.000569	3.25	0.000407	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0001505	regulation of neurotransmitter levels	BP	0.0472	2.02e-05	0.000574	3.24	0.000411	Syn2/Maob/Slc6a2/Rims3/Adra1a/Drd4/Nlgn1/Abat/Edn3/P2rx2/Ppfia2/Cadps	12
GO:0010811	positive regulation of cell-substrate adhesion	BP	0.0643	2.04e-05	0.000574	3.24	0.000411	Vit/Col26a1/Mdk/Npnt/Kdr/Spock2/Foxf1/Has2/Nid1	9
GO:1904036	negative regulation of epithelial cell apoptotic process	BP	0.113	2.1e-05	0.000588	3.23	0.00042	Angpt1/Sema5a/Mdk/Igf1/Kdr/Tert	6
GO:0061326	renal tubule development	BP	0.0741	2.12e-05	0.000589	3.23	0.000421	Wnt6/Nog/Hoxd11/Adamts16/Npnt/Gpc3/Hoxa11/Cd44	8
GO:0031345	negative regulation of cell projection organization	BP	0.0512	2.15e-05	0.000593	3.23	0.000424	Ptprz1/Efnb3/Map2/Sema5a/Sema5b/Nlgn1/Dab1/Ntm/Evl/Grin2b/Sema7a	11
GO:0048704	embryonic skeletal system morphogenesis	BP	0.0734	2.27e-05	0.00062	3.21	0.000444	Col11a1/Mmp16/Nog/Hoxd10/Hoxd11/Hoxa11/Osr2/Hoxd9	8
GO:0006816	calcium ion transport	BP	0.0364	2.33e-05	0.00063	3.2	0.000451	Nalcn/Spink1/Ryr1/Adra1a/Drd4/Igf1/Jph4/Slc24a4/Ednrb/Stc1/Calca/Nos3/Cacna1e/Grin2b/Slc8a3/Cxcl12	16
GO:0072132	mesenchyme morphogenesis	BP	0.111	2.34e-05	0.00063	3.2	0.000451	Wnt11/Lef1/Nog/Tbx2/Foxf1/Nos3	6
GO:0034329	cell junction assembly	BP	0.0363	2.39e-05	0.00064	3.19	0.000458	Gap43/Gpc6/Sdk2/Wnt11/St8sia2/Ptpro/Nlgn1/Ptprd/Plxnb1/Nptx1/Kdr/Epb41l3/Lrrc4b/Cdh6/Cdh2/Cdh10	16
GO:0070482	response to oxygen levels	BP	0.043	2.44e-05	0.000641	3.19	0.000458	Kcnk3/Kcnd2/Ryr1/Ddah1/Abat/Kdr/Pygm/Cbs/P2rx2/Grin2b/Tert/Slc8a3/Mmp2	13
GO:0010001	glial cell differentiation	BP	0.0463	2.45e-05	0.000641	3.19	0.000458	Gap43/Ptprz1/Lef1/Mdk/Nog/Igf1/Lamc3/Cdh2/Dab1/Serpine2/Wasf3/Slc8a3	12
GO:0060740	prostate gland epithelium morphogenesis	BP	0.152	2.47e-05	0.000641	3.19	0.000458	Nog/Igf1/Cyp7b1/Cd44/Mmp2	5
GO:0062149	detection of stimulus involved in sensory perception of pain	BP	0.152	2.47e-05	0.000641	3.19	0.000458	Scn1a/Calca/Grin2b/Ano1/Cxcl12	5
GO:0031346	positive regulation of cell projection organization	BP	0.0361	2.53e-05	0.000651	3.19	0.000466	Ptprz1/Hgf/Fez1/Sema5a/Dcc/Acsl6/Mdk/Lrrc7/Nlgn1/Ptprd/Plxnb1/Tenm3/Sema7a/Serpine2/Cxcl12/Ccdc88a	16
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	BP	0.0714	2.76e-05	0.000706	3.15	0.000505	Prtg/Hmcn1/Sdk2/Pcdh18/Cdh6/Cdh2/Tenm3/Cdh10	8
GO:0048706	embryonic skeletal system development	BP	0.0616	2.84e-05	0.000718	3.14	0.000514	Ihh/Col11a1/Mmp16/Nog/Hoxd10/Hoxd11/Hoxa11/Osr2/Hoxd9	9
GO:0060512	prostate gland morphogenesis	BP	0.147	2.87e-05	0.000718	3.14	0.000514	Nog/Igf1/Cyp7b1/Cd44/Mmp2	5
GO:0099560	synaptic membrane adhesion	BP	0.147	2.87e-05	0.000718	3.14	0.000514	Gpc6/Lrrc4c/Nlgn1/Ptprd/Lrrc4b	5
GO:0019932	second-messenger-mediated signaling	BP	0.0421	3.1e-05	0.000765	3.12	0.000547	Spink1/Sgcd/Drd4/Nr5a2/Igf1/Slc24a4/Kdr/Ednrb/Cbs/Nos3/Gnai1/Edn3/Ptgfr	13
GO:0050770	regulation of axonogenesis	BP	0.0541	3.19e-05	0.000779	3.11	0.000557	Efnb3/Map2/Sema5a/Lrrc4c/Sema5b/Plxnb1/Cdh2/Dab1/Sema7a/Cxcl12	10
GO:0010463	mesenchymal cell proliferation	BP	0.105	3.2e-05	0.000779	3.11	0.000557	Ihh/Wnt11/Tbx2/Kdr/Gpc3/Foxf1	6
GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	BP	0.143	3.32e-05	0.000802	3.1	0.000574	Pcdh18/Nlgn1/Cdh6/Cdh2/Cdh10	5
GO:0002062	chondrocyte differentiation	BP	0.0696	3.34e-05	0.000802	3.1	0.000574	Ihh/Col11a1/Sfrp2/Mdk/Pkdcc/Hoxd11/Hoxa11/Osr2	8
GO:0099150	regulation of postsynaptic specialization assembly	BP	0.222	3.44e-05	0.000819	3.09	0.000586	Gap43/Ptprd/Nptx1/Lrrc4b	4
GO:0035725	sodium ion transmembrane transport	BP	0.06	3.51e-05	0.000832	3.08	0.000595	Nalcn/Slc6a2/Drd4/Scn4b/Slc24a4/Scn1a/Hecw2/Slc9a7/Slc8a3	9
GO:0006939	smooth muscle contraction	BP	0.0684	3.78e-05	0.00089	3.05	0.000636	Adra1a/Tbx2/Npnt/Abat/Ednrb/Calca/Edn3/P2rx2	8
GO:0030111	regulation of Wnt signaling pathway	BP	0.0409	4.16e-05	0.000973	3.01	0.000696	Gli1/Sfrp2/Wnt11/Lef1/Sema5a/Apcdd1/Mdk/Nog/Ptpro/Gpc3/Cdh2/Nkd1/Tert	13
GO:1905874	regulation of postsynaptic density organization	BP	0.211	4.32e-05	0.001	3	0.000717	Ptprd/Nptx1/Lrrc4b/Cdh2	4
GO:2000177	regulation of neural precursor cell proliferation	BP	0.0667	4.54e-05	0.00105	2.98	0.000748	Gli1/Ptprz1/Mdk/Nog/Igf1/Cdh2/Lrp2/Smarca1	8
GO:0007416	synapse assembly	BP	0.0518	4.57e-05	0.00105	2.98	0.000749	Gap43/Gpc6/Sdk2/St8sia2/Nlgn1/Ptprd/Plxnb1/Nptx1/Lrrc4b/Cdh2	10
GO:0048588	developmental cell growth	BP	0.0433	4.71e-05	0.00106	2.97	0.000761	Map2/Sema5a/St8sia2/Col14a1/Adra1a/Sema5b/Igf1/Cpne5/Itga4/Edn3/Sema7a/Cxcl12	12
GO:0060324	face development	BP	0.0984	4.73e-05	0.00106	2.97	0.000761	Stra6/Lef1/Nog/Crispld1/Itga4/Mmp2	6
GO:1904019	epithelial cell apoptotic process	BP	0.0661	4.81e-05	0.00107	2.97	0.000769	Angpt1/Sema5a/Mdk/Igf1/Itga4/Kdr/Tert/Bok	8
GO:0003018	vascular process in circulatory system	BP	0.0468	4.85e-05	0.00108	2.97	0.00077	Angpt1/Adra1a/Ddah1/Kdr/Ednrb/Calca/Cbs/Nos3/Edn3/Mmp2/Npr3	11
GO:0097106	postsynaptic density organization	BP	0.132	5e-05	0.0011	2.96	0.000788	Nlgn1/Ptprd/Nptx1/Lrrc4b/Cdh2	5
GO:0050982	detection of mechanical stimulus	BP	0.0968	5.19e-05	0.00114	2.94	0.000813	Col11a1/Igf1/Scn1a/Grin2b/Serpine2/Cxcl12	6
GO:0031589	cell-substrate adhesion	BP	0.0375	5.36e-05	0.00117	2.93	0.000836	Ptprz1/Vit/Col26a1/Angpt1/Mdk/Lamc3/Itga4/Npnt/Kdr/Spock2/Foxf1/Has2/Frem1/Nid1	14
GO:0008016	regulation of heart contraction	BP	0.0508	5.43e-05	0.00118	2.93	0.000841	Kcnd3/Adra1a/Scn4b/Ednrb/Stc1/Calca/Nos3/Hopx/Edn3/Cacna1e	10
GO:0043010	camera-type eye development	BP	0.0374	5.52e-05	0.00119	2.93	0.000849	Ndp/Cyp1b1/Ihh/Stra6/Sdk2/Nhs/Tbx2/Tub/Lamc3/Kdr/Celf4/Rcn1/Tenm3/Osr2	14
GO:0045879	negative regulation of smoothened signaling pathway	BP	0.128	5.69e-05	0.00122	2.92	0.000869	Gli1/Hhip/Gpc3/Serpine2/Kif7	5
GO:0060079	excitatory postsynaptic potential	BP	0.0761	5.88e-05	0.00125	2.9	0.000894	Grik1/Begain/Drd4/Nlgn1/Celf4/Grin2b/Slc8a3	7
GO:0003007	heart morphogenesis	BP	0.0423	5.98e-05	0.00126	2.9	0.000904	Ihh/Col11a1/Sfrp2/Wnt11/Angpt1/Ryr1/Nog/Tbx2/Foxf1/Nos3/Has2/Lrp2	12
GO:0003205	cardiac chamber development	BP	0.05	6.16e-05	0.00129	2.89	0.000926	Stra6/Col11a1/Sfrp2/Wnt11/Nog/Tbx2/Foxf1/Nos3/Lrp2/Kif7	10
GO:0048880	sensory system development	BP	0.035	6.34e-05	0.00131	2.88	0.000936	Ndp/Tmem132e/Cyp1b1/Ihh/Stra6/Sdk2/Nhs/Tbx2/Tub/Lamc3/Kdr/Celf4/Rcn1/Tenm3/Osr2	15
GO:0010977	negative regulation of neuron projection development	BP	0.0556	6.4e-05	0.00131	2.88	0.000936	Ptprz1/Efnb3/Map2/Sema5a/Sema5b/Nlgn1/Dab1/Ntm/Sema7a	9
GO:0048565	digestive tract development	BP	0.0635	6.42e-05	0.00131	2.88	0.000936	Ihh/Stra6/Sfrp2/Pkdcc/Tbx2/Ednrb/Foxf1/Clmp	8
GO:0060325	face morphogenesis	BP	0.125	6.44e-05	0.00131	2.88	0.000936	Stra6/Lef1/Nog/Crispld1/Mmp2	5
GO:0060351	cartilage development involved in endochondral bone morphogenesis	BP	0.125	6.44e-05	0.00131	2.88	0.000936	Ihh/Hoxd11/Hoxa11/Stc1/Cbs	5
GO:0009100	glycoprotein metabolic process	BP	0.0392	6.46e-05	0.00131	2.88	0.000936	Ihh/Col11a1/St6gal2/St8sia2/Igf1/Itm2a/Spock2/Tet1/St8sia4/Chst10/Gxylt2/Tmtc1/Soat1	13
GO:0045165	cell fate commitment	BP	0.0418	6.61e-05	0.00133	2.88	0.000953	Gap43/Ihh/Wnt6/Sfrp2/Wnt11/AW551984/Ptch2/Hoxd10/Tbx2/Kdr/Hoxa11/Gdf7	12
GO:0050768	negative regulation of neurogenesis	BP	0.0552	6.71e-05	0.00135	2.87	0.000962	Prtg/Efnb3/Map2/Sema5a/Nog/Sema5b/Dab1/Sema7a/Tert	9
GO:0008589	regulation of smoothened signaling pathway	BP	0.0745	6.75e-05	0.00135	2.87	0.000962	Gli1/Ihh/Hhip/Evc/Gpc3/Serpine2/Kif7	7
GO:0014706	striated muscle tissue development	BP	0.0414	7.3e-05	0.00145	2.84	0.00103	Gli1/Col11a1/Lef1/AW551984/Angpt1/Col14a1/Sgcd/Nog/Adra1a/Tbx2/Igf1/Lrp2	12
GO:0048286	lung alveolus development	BP	0.0909	7.4e-05	0.00146	2.84	0.00104	Stra6/Pkdcc/Igf1/Kdr/Foxf1/Hopx	6
GO:0014013	regulation of gliogenesis	BP	0.062	7.58e-05	0.00148	2.83	0.00106	Ptprz1/Mdk/Nog/Igf1/Dab1/Lrp2/Tert/Serpine2	8
GO:0060438	trachea development	BP	0.182	7.94e-05	0.00155	2.81	0.00111	Lef1/Edaradd/Foxf1/Ano1	4
GO:0001707	mesoderm formation	BP	0.0896	8.05e-05	0.00155	2.81	0.00111	Sfrp2/Wnt11/Lef1/Nog/Hoxa11/Foxf1	6
GO:0060350	endochondral bone morphogenesis	BP	0.0896	8.05e-05	0.00155	2.81	0.00111	Ihh/Mmp16/Hoxd11/Hoxa11/Stc1/Cbs	6
GO:0051961	negative regulation of nervous system development	BP	0.0539	8.09e-05	0.00155	2.81	0.00111	Prtg/Efnb3/Map2/Sema5a/Nog/Sema5b/Dab1/Sema7a/Tert	9
GO:0042692	muscle cell differentiation	BP	0.0342	8.2e-05	0.00156	2.81	0.00112	AW551984/Ryr1/Col14a1/Sgcd/Adra1a/Tbx2/Igf1/Npnt/Ednrb/Tmod2/Cdh2/Foxf1/Hopx/P2rx2/Cxcl12	15
GO:0045880	positive regulation of smoothened signaling pathway	BP	0.116	9.18e-05	0.00174	2.76	0.00125	Gli1/Ihh/Evc/Gpc3/Kif7	5
GO:0050769	positive regulation of neurogenesis	BP	0.0403	9.45e-05	0.00178	2.75	0.00127	Ptprz1/Sema5a/Mdk/Nog/Igf1/Ptprd/Plxnb1/Kdr/Lrp2/Sema7a/Serpine2/Cxcl12	12
GO:0006820	anion transport	BP	0.0321	0.000101	0.00188	2.73	0.00134	Car4/Slc1a3/Grik1/Pla2g10/Slc13a5/Slc2a3/Drd4/Abat/Slc12a8/Ano2/Stc1/Lrp2/Grin2b/Ano1/Slc7a2/Gabra4	16
GO:0071695	anatomical structure maturation	BP	0.04	0.000101	0.00188	2.73	0.00134	Epha8/Ihh/Pla2g10/Spink1/Ryr1/Igf1/Slc24a4/Plxnb1/Kdr/Ednrb/Calca/Mmp2	12
GO:0050771	negative regulation of axonogenesis	BP	0.0857	0.000103	0.00191	2.72	0.00137	Efnb3/Map2/Sema5a/Sema5b/Dab1/Sema7a	6
GO:0006874	cellular calcium ion homeostasis	BP	0.032	0.000105	0.00194	2.71	0.00139	Kcnk3/Ryr1/Adra1a/Slc24a4/Kdr/Ednrb/Pygm/Stc1/Calca/Edn3/P2rx2/Ptgfr/Cacna1e/Grin2b/Bok/Slc8a3	16
GO:0035296	regulation of tube diameter	BP	0.052	0.000106	0.00194	2.71	0.00139	Adra1a/Kdr/Ednrb/Calca/Cbs/Nos3/Edn3/Mmp2/Npr3	9
GO:0097746	blood vessel diameter maintenance	BP	0.052	0.000106	0.00194	2.71	0.00139	Adra1a/Kdr/Ednrb/Calca/Cbs/Nos3/Edn3/Mmp2/Npr3	9
GO:0014065	phosphatidylinositol 3-kinase signaling	BP	0.0588	0.00011	0.002	2.7	0.00143	Hgf/Myo16/Angpt1/Igf1/Plxnb1/Kdr/Serpine2/Agap2	8
GO:0035150	regulation of tube size	BP	0.0517	0.000111	0.002	2.7	0.00143	Adra1a/Kdr/Ednrb/Calca/Cbs/Nos3/Edn3/Mmp2/Npr3	9
GO:0048332	mesoderm morphogenesis	BP	0.0845	0.000112	0.00201	2.7	0.00144	Sfrp2/Wnt11/Lef1/Nog/Hoxa11/Foxf1	6
GO:0001708	cell fate specification	BP	0.0686	0.000113	0.00203	2.69	0.00145	Ihh/Sfrp2/Wnt11/Ptch2/Hoxd10/Tbx2/Hoxa11	7
GO:0050918	positive chemotaxis	BP	0.111	0.000115	0.00204	2.69	0.00146	Angpt1/Sema5a/Kdr/Lrp2/Cxcl12	5
GO:0033002	muscle cell proliferation	BP	0.0425	0.000116	0.00205	2.69	0.00146	Gli1/Angpt1/Vipr2/Nog/Drd4/Tbx2/Igf1/Nos3/Tert/Mmp2/Npr3	11
GO:0048638	regulation of developmental growth	BP	0.0348	0.000118	0.00209	2.68	0.00149	Gli1/Map2/Sema5a/H19/Col14a1/Nog/Sema5b/Tbx2/Igf1/Cpne5/Nkd1/Hopx/Sema7a/Cxcl12	14
GO:0014066	regulation of phosphatidylinositol 3-kinase signaling	BP	0.068	0.00012	0.00211	2.68	0.00151	Hgf/Angpt1/Igf1/Plxnb1/Kdr/Serpine2/Agap2	7
GO:0030509	BMP signaling pathway	BP	0.0511	0.000121	0.00211	2.68	0.00151	Sfrp2/Lef1/Nog/Fst/Rnf165/Kdr/Gpc3/Lrp2/Gdf7	9
GO:0032102	negative regulation of response to external stimulus	BP	0.0347	0.000122	0.00211	2.68	0.00151	Acod1/Hgf/Pla2g10/Sema5a/Cd109/Mdk/Sema5b/Igf1/Abat/Tfpi/Foxf1/Cd44/Sema7a/Serpine2	14
GO:0043271	negative regulation of ion transport	BP	0.0508	0.000126	0.00218	2.66	0.00156	Maob/Spink1/Drd4/Abat/Hecw2/Stc1/Calca/Nos3/Serpine2	9
GO:0030510	regulation of BMP signaling pathway	BP	0.0673	0.000128	0.0022	2.66	0.00157	Sfrp2/Nog/Fst/Rnf165/Kdr/Gpc3/Lrp2	7
GO:0050807	regulation of synapse organization	BP	0.0418	0.000132	0.00226	2.65	0.00162	Gpc6/St8sia2/Rims3/Ptpro/Nlgn1/Ptprd/Nptx1/Lrrc4b/Cdh2/Ppfia2/Grin2b	11
GO:0007620	copulation	BP	0.16	0.000134	0.00227	2.64	0.00163	Drd4/Abat/Ednrb/Serpine2	4
GO:0035988	chondrocyte proliferation	BP	0.16	0.000134	0.00227	2.64	0.00163	Ihh/Mmp16/Lef1/Stc1	4
GO:0050890	cognition	BP	0.0362	0.000141	0.00237	2.62	0.0017	Stra6/Ptprz1/Mdk/Nog/Drd4/Igf1/Jph4/Cyp7b1/Tmod2/Chst10/Cacna1e/Grin2b/Slc8a3	13
GO:0001558	regulation of cell growth	BP	0.0325	0.000144	0.00241	2.62	0.00172	Sfrp2/Map2/Wnt11/Tro/Sema5a/Ptch2/Col14a1/Sema5b/Igf1/Cpne5/Epb41l3/Cd44/Sema7a/Serpine2/Cxcl12	15
GO:1903522	regulation of blood circulation	BP	0.0414	0.000146	0.00243	2.61	0.00174	Kcnd3/Adra1a/Scn4b/Ednrb/Stc1/Calca/Nos3/Hopx/Edn3/Cacna1e/Mmp2	11
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	BP	0.08	0.000151	0.00251	2.6	0.00179	Hgf/Angpt1/Igf1/Plxnb1/Kdr/Agap2	6
GO:0060326	cell chemotaxis	BP	0.0382	0.000154	0.00254	2.6	0.00182	Cxcl15/Hgf/Lef1/Sema5a/Mdk/Ptpro/Cyp7b1/Kdr/Ednrb/Calca/Edn3/Cxcl12	12
GO:0035137	hindlimb morphogenesis	BP	0.104	0.000156	0.00257	2.59	0.00183	Aff3/Hoxd10/Gpc3/Osr2/Hoxd9	5
GO:0045766	positive regulation of angiogenesis	BP	0.0492	0.000162	0.00264	2.58	0.00189	Cyp1b1/Hgf/Sfrp2/Sema5a/Mdk/Ddah1/Kdr/Nos3/Tert	9
GO:1904018	positive regulation of vasculature development	BP	0.0492	0.000162	0.00264	2.58	0.00189	Cyp1b1/Hgf/Sfrp2/Sema5a/Mdk/Ddah1/Kdr/Nos3/Tert	9
GO:0048738	cardiac muscle tissue development	BP	0.0407	0.000166	0.00269	2.57	0.00192	Gli1/Col11a1/AW551984/Angpt1/Col14a1/Sgcd/Nog/Adra1a/Tbx2/Igf1/Lrp2	11
GO:0050803	regulation of synapse structure or activity	BP	0.0406	0.000172	0.00276	2.56	0.00198	Gpc6/St8sia2/Rims3/Ptpro/Nlgn1/Ptprd/Nptx1/Lrrc4b/Cdh2/Ppfia2/Grin2b	11
GO:0010810	regulation of cell-substrate adhesion	BP	0.0441	0.000175	0.00278	2.56	0.00199	Ptprz1/Vit/Col26a1/Mdk/Npnt/Kdr/Spock2/Foxf1/Has2/Nid1	10
GO:0007269	neurotransmitter secretion	BP	0.0486	0.000176	0.00278	2.56	0.00199	Syn2/Rims3/Adra1a/Drd4/Nlgn1/Edn3/P2rx2/Ppfia2/Cadps	9
GO:0099643	signal release from synapse	BP	0.0486	0.000176	0.00278	2.56	0.00199	Syn2/Rims3/Adra1a/Drd4/Nlgn1/Edn3/P2rx2/Ppfia2/Cadps	9
GO:1903305	regulation of regulated secretory pathway	BP	0.0486	0.000176	0.00278	2.56	0.00199	Rims3/Adra1a/Drd4/Syt13/Nlgn1/Foxf1/P2rx2/Ppfia2/Cadps	9
GO:0014821	phasic smooth muscle contraction	BP	0.148	0.000183	0.00287	2.54	0.00205	Tbx2/Ednrb/Edn3/P2rx2	4
GO:0099545	trans-synaptic signaling by trans-synaptic complex	BP	0.273	0.000185	0.0029	2.54	0.00207	Efnb3/Nlgn1/Ptprd	3
GO:0001654	eye development	BP	0.0333	0.000191	0.00296	2.53	0.00212	Ndp/Cyp1b1/Ihh/Stra6/Sdk2/Nhs/Tbx2/Tub/Lamc3/Kdr/Celf4/Rcn1/Tenm3/Osr2	14
GO:0008344	adult locomotory behavior	BP	0.0631	0.000192	0.00296	2.53	0.00212	Efnb3/Hoxd10/Drd4/Scn1a/Dab1/Hoxd9/Cxcl12	7
GO:0099175	regulation of postsynapse organization	BP	0.0631	0.000192	0.00296	2.53	0.00212	Nlgn1/Ptprd/Nptx1/Lrrc4b/Cdh2/Ppfia2/Grin2b	7
GO:0002027	regulation of heart rate	BP	0.0625	0.000203	0.00311	2.51	0.00223	Kcnd3/Adra1a/Scn4b/Ednrb/Calca/Edn3/Cacna1e	7
GO:0150063	visual system development	BP	0.033	0.000205	0.00313	2.5	0.00224	Ndp/Cyp1b1/Ihh/Stra6/Sdk2/Nhs/Tbx2/Tub/Lamc3/Kdr/Celf4/Rcn1/Tenm3/Osr2	14
GO:0019233	sensory perception of pain	BP	0.0537	0.000206	0.00313	2.5	0.00224	Kcnd2/Scn1a/Ednrb/Calca/Cacna1e/Grin2b/Ano1/Cxcl12	8
GO:0008038	neuron recognition	BP	0.098	0.000209	0.00315	2.5	0.00225	Gap43/Ptprz1/Prtg/Efnb3/Sema5a	5
GO:0003231	cardiac ventricle development	BP	0.053	0.000226	0.00339	2.47	0.00242	Stra6/Col11a1/Sfrp2/Wnt11/Nog/Foxf1/Nos3/Lrp2	8
GO:0061756	leukocyte adhesion to vascular endothelial cell	BP	0.0962	0.000229	0.00343	2.47	0.00245	Mdk/Itga4/Chst2/Cxcl12/Podxl2	5
GO:0009952	anterior/posterior pattern specification	BP	0.0426	0.000231	0.00344	2.46	0.00246	Sfrp2/Lef1/Nog/Hoxd10/Hoxd11/Gpc3/Hoxa11/Foxf1/Hoxa10/Hoxd9	10
GO:0003206	cardiac chamber morphogenesis	BP	0.0526	0.000236	0.0035	2.46	0.0025	Col11a1/Sfrp2/Wnt11/Nog/Tbx2/Foxf1/Nos3/Lrp2	8
GO:1904861	excitatory synapse assembly	BP	0.138	0.000243	0.00359	2.44	0.00257	Nlgn1/Ptprd/Nptx1/Lrrc4b	4
GO:0014015	positive regulation of gliogenesis	BP	0.0732	0.000247	0.00364	2.44	0.0026	Ptprz1/Mdk/Nog/Igf1/Lrp2/Serpine2	6
GO:0030850	prostate gland development	BP	0.0943	0.000251	0.00364	2.44	0.00261	Nog/Igf1/Cyp7b1/Cd44/Mmp2	5
GO:2000351	regulation of endothelial cell apoptotic process	BP	0.0943	0.000251	0.00364	2.44	0.00261	Angpt1/Sema5a/Itga4/Kdr/Tert	5
GO:0098659	inorganic cation import across plasma membrane	BP	0.0603	0.000252	0.00364	2.44	0.00261	Kcnj3/Kcnd3/Slc24a4/Slc12a8/Cacna1e/Slc9a7/Slc8a3	7
GO:0099587	inorganic ion import across plasma membrane	BP	0.0603	0.000252	0.00364	2.44	0.00261	Kcnj3/Kcnd3/Slc24a4/Slc12a8/Cacna1e/Slc9a7/Slc8a3	7
GO:0007159	leukocyte cell-cell adhesion	BP	0.0339	0.000264	0.0038	2.42	0.00272	Ihh/Efnb3/Lef1/Cd83/Mdk/Igf1/Itga4/Chst2/Calca/Cd44/Has2/Cxcl12/Podxl2	13
GO:0035249	synaptic transmission, glutamatergic	BP	0.0598	0.000266	0.00381	2.42	0.00272	Grid1/Grik1/Gria4/Nlgn1/Cdh2/Grin2b/Serpine2	7
GO:0032892	positive regulation of organic acid transport	BP	0.0926	0.000274	0.00392	2.41	0.0028	Grik1/Pla2g10/Acsl6/Abat/Grin2b	5
GO:0031099	regeneration	BP	0.0513	0.000281	0.004	2.4	0.00286	Gli1/Gap43/Hgf/Mdk/Igf1/Hopx/Mmp2/Cxcl12	8
GO:2000300	regulation of synaptic vesicle exocytosis	BP	0.0714	0.000282	0.004	2.4	0.00286	Rims3/Adra1a/Drd4/Nlgn1/P2rx2/Ppfia2	6
GO:0006836	neurotransmitter transport	BP	0.0413	0.000292	0.00412	2.38	0.00295	Syn2/Slc6a2/Rims3/Adra1a/Drd4/Nlgn1/Edn3/P2rx2/Ppfia2/Cadps	10
GO:0001662	behavioral fear response	BP	0.0909	0.000299	0.00419	2.38	0.00299	Ankfn1/Mdk/Drd4/Cacna1e/Grin2b	5
GO:1902476	chloride transmembrane transport	BP	0.0909	0.000299	0.00419	2.38	0.00299	Slc1a3/Slc12a8/Ano2/Ano1/Gabra4	5
GO:0051966	regulation of synaptic transmission, glutamatergic	BP	0.0706	0.000301	0.00419	2.38	0.003	Grik1/Gria4/Nlgn1/Cdh2/Grin2b/Serpine2	6
GO:0048570	notochord morphogenesis	BP	0.231	0.000316	0.00432	2.36	0.00309	Gli1/Wnt11/Nog	3
GO:0061036	positive regulation of cartilage development	BP	0.129	0.000317	0.00432	2.36	0.00309	Mdk/Pkdcc/Hoxd11/Hoxa11	4
GO:2000352	negative regulation of endothelial cell apoptotic process	BP	0.129	0.000317	0.00432	2.36	0.00309	Angpt1/Sema5a/Kdr/Tert	4
GO:0072577	endothelial cell apoptotic process	BP	0.0893	0.000325	0.0044	2.36	0.00315	Angpt1/Sema5a/Itga4/Kdr/Tert	5
GO:0046928	regulation of neurotransmitter secretion	BP	0.0574	0.000343	0.00462	2.34	0.0033	Rims3/Adra1a/Drd4/Nlgn1/Edn3/P2rx2/Ppfia2	7
GO:0007613	memory	BP	0.0497	0.000348	0.00467	2.33	0.00334	Mdk/Nog/Drd4/Igf1/Cyp7b1/Chst10/Grin2b/Slc8a3	8
GO:1903039	positive regulation of leukocyte cell-cell adhesion	BP	0.0403	0.000355	0.00474	2.32	0.00339	Ihh/Efnb3/Lef1/Cd83/Mdk/Igf1/Itga4/Chst2/Cd44/Has2	10
GO:1990138	neuron projection extension	BP	0.0441	0.000363	0.0048	2.32	0.00343	Map2/Sema5a/St8sia2/Sema5b/Cpne5/Itga4/Edn3/Sema7a/Cxcl12	9
GO:0003151	outflow tract morphogenesis	BP	0.0682	0.000363	0.0048	2.32	0.00343	Sfrp2/Wnt11/Ryr1/Nog/Tbx2/Lrp2	6
GO:0021675	nerve development	BP	0.0682	0.000363	0.0048	2.32	0.00343	Slc1a3/Rnf165/Slc24a4/Itga4/Nptx1/Serpine2	6
GO:0060828	regulation of canonical Wnt signaling pathway	BP	0.0402	0.000366	0.00482	2.32	0.00345	Gli1/Sfrp2/Wnt11/Sema5a/Mdk/Nog/Ptpro/Gpc3/Cdh2/Nkd1	10
GO:0051480	regulation of cytosolic calcium ion concentration	BP	0.0327	0.000372	0.00488	2.31	0.00349	Kcnk3/Ryr1/Adra1a/Slc24a4/Kdr/Ednrb/Calca/P2rx2/Ptgfr/Cacna1e/Grin2b/Bok/Slc8a3	13
GO:0014032	neural crest cell development	BP	0.0674	0.000386	0.00504	2.3	0.0036	Sema5a/Sema5b/Ednrb/Cdh2/Edn3/Sema7a	6
GO:0099151	regulation of postsynaptic density assembly	BP	0.214	4e-04	0.0052	2.28	0.00372	Ptprd/Nptx1/Lrrc4b	3
GO:0033687	osteoblast proliferation	BP	0.121	0.000405	0.00522	2.28	0.00373	Plxnb1/Osr2/Nell1/Npr3	4
GO:0048566	embryonic digestive tract development	BP	0.121	0.000405	0.00522	2.28	0.00373	Ihh/Stra6/Pkdcc/Foxf1	4
GO:0048841	regulation of axon extension involved in axon guidance	BP	0.121	0.000405	0.00522	2.28	0.00373	Sema5a/Sema5b/Sema7a/Cxcl12	4
GO:0090287	regulation of cellular response to growth factor stimulus	BP	0.0367	0.000409	0.00524	2.28	0.00375	Sfrp2/Hhip/Angpt1/Cd109/Nog/Fst/Rnf165/Npnt/Kdr/Gpc3/Lrp2	11
GO:0098815	modulation of excitatory postsynaptic potential	BP	0.0833	0.000449	0.00574	2.24	0.00411	Drd4/Nlgn1/Celf4/Grin2b/Slc8a3	5
GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.0391	0.000455	0.00578	2.24	0.00413	Sfrp2/Cd109/Nog/Fst/Rnf165/Npnt/Kdr/Gpc3/Lrp2/Gdf7	10
GO:1904994	regulation of leukocyte adhesion to vascular endothelial cell	BP	0.118	0.000455	0.00578	2.24	0.00413	Mdk/Itga4/Chst2/Cxcl12	4
GO:0048640	negative regulation of developmental growth	BP	0.0547	0.000458	0.0058	2.24	0.00415	Map2/Sema5a/H19/Nog/Sema5b/Nkd1/Sema7a	7
GO:0042476	odontogenesis	BP	0.0543	0.00048	0.00603	2.22	0.00431	Wnt6/Lef1/Apcdd1/Fst/Slc24a4/Edaradd/Osr2	7
GO:0031641	regulation of myelination	BP	0.082	0.000485	0.00605	2.22	0.00433	Ptprz1/Hgf/Igf1/Cdh2/Wasf3	5
GO:0042596	fear response	BP	0.082	0.000485	0.00605	2.22	0.00433	Ankfn1/Mdk/Drd4/Cacna1e/Grin2b	5
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	BP	0.2	0.000496	0.00616	2.21	0.0044	Sfrp2/Gpc3/Nkd1	3
GO:0003279	cardiac septum development	BP	0.0538	0.000503	0.00623	2.21	0.00445	Stra6/Wnt11/Nog/Tbx2/Nos3/Lrp2/Kif7	7
GO:0003401	axis elongation	BP	0.114	0.00051	0.00629	2.2	0.0045	Sfrp2/Wnt11/Areg/Nkd1	4
GO:0042475	odontogenesis of dentin-containing tooth	BP	0.0638	0.000517	0.00636	2.2	0.00455	Wnt6/Lef1/Apcdd1/Fst/Slc24a4/Edaradd	6
GO:0014031	mesenchymal cell development	BP	0.0632	0.000547	0.00661	2.18	0.00473	Sema5a/Sema5b/Ednrb/Cdh2/Edn3/Sema7a	6
GO:0014910	regulation of smooth muscle cell migration	BP	0.0632	0.000547	0.00661	2.18	0.00473	Cyp1b1/Mdk/Drd4/Igf1/Has2/Tert	6
GO:0048864	stem cell development	BP	0.0632	0.000547	0.00661	2.18	0.00473	Sema5a/Sema5b/Ednrb/Cdh2/Edn3/Sema7a	6
GO:0061053	somite development	BP	0.0632	0.000547	0.00661	2.18	0.00473	Ihh/Sfrp2/Wnt11/Lef1/Nog/Foxf1	6
GO:0022407	regulation of cell-cell adhesion	BP	0.0299	0.000551	0.00663	2.18	0.00474	Ihh/Efnb3/Lef1/Cd83/Mdk/Igf1/Itga4/Abat/Chst2/Tenm3/Cd44/Has2/Serpine2/Cxcl12	14
GO:0001755	neural crest cell migration	BP	0.0794	0.000564	0.00676	2.17	0.00484	Sema5a/Sema5b/Ednrb/Edn3/Sema7a	5
GO:0035115	embryonic forelimb morphogenesis	BP	0.111	0.000569	0.00678	2.17	0.00485	Hoxd11/Hoxa11/Osr2/Hoxd9	4
GO:0070509	calcium ion import	BP	0.0625	0.000578	0.00687	2.16	0.00491	Spink1/Slc24a4/Stc1/Cacna1e/Slc8a3/Cxcl12	6
GO:0060026	convergent extension	BP	0.188	0.000605	0.00715	2.15	0.00511	Sfrp2/Wnt11/Nkd1	3
GO:0014911	positive regulation of smooth muscle cell migration	BP	0.0781	0.000606	0.00715	2.15	0.00511	Cyp1b1/Mdk/Igf1/Has2/Tert	5
GO:0048846	axon extension involved in axon guidance	BP	0.108	0.000633	0.00734	2.13	0.00525	Sema5a/Sema5b/Sema7a/Cxcl12	4
GO:0050901	leukocyte tethering or rolling	BP	0.108	0.000633	0.00734	2.13	0.00525	Itga4/Chst2/Cxcl12/Podxl2	4
GO:0060071	Wnt signaling pathway, planar cell polarity pathway	BP	0.108	0.000633	0.00734	2.13	0.00525	Sfrp2/Wnt11/Gpc3/Nkd1	4
GO:1902284	neuron projection extension involved in neuron projection guidance	BP	0.108	0.000633	0.00734	2.13	0.00525	Sema5a/Sema5b/Sema7a/Cxcl12	4
GO:0007548	sex differentiation	BP	0.0347	0.000646	0.00745	2.13	0.00533	Tex15/Stra6/Sfrp2/Angpt1/Fst/Kdr/Hoxa11/Hoxa10/Nos3/Lrp2/Mmp2	11
GO:0032835	glomerulus development	BP	0.0769	0.000651	0.00748	2.13	0.00535	Angpt1/Nog/Ptpro/Ednrb/Nid1	5
GO:0001649	osteoblast differentiation	BP	0.0405	0.000668	0.00765	2.12	0.00547	Gli1/Ihh/Sfrp2/Wnt11/Nog/Igf1/Areg/Npnt/Nell1	9
GO:0030902	hindbrain development	BP	0.0449	0.000677	0.00772	2.11	0.00552	Gli1/Lef1/Mdk/Nog/Igf1/Dab1/Cbs/Serpine2	8
GO:0001938	positive regulation of endothelial cell proliferation	BP	0.0606	0.000681	0.00772	2.11	0.00552	Sema5a/Mdk/Igf1/Itga4/Kdr/Cxcl12	6
GO:0014033	neural crest cell differentiation	BP	0.0606	0.000681	0.00772	2.11	0.00552	Sema5a/Sema5b/Ednrb/Cdh2/Edn3/Sema7a	6
GO:0016079	synaptic vesicle exocytosis	BP	0.0511	0.000688	0.00773	2.11	0.00553	Rims3/Adra1a/Drd4/Nlgn1/P2rx2/Ppfia2/Cadps	7
GO:0042633	hair cycle	BP	0.0511	0.000688	0.00773	2.11	0.00553	Pla2g10/Apcdd1/Cd109/Ptch2/Fst/Edaradd/Tert	7
GO:0045776	negative regulation of blood pressure	BP	0.0758	0.000698	0.00782	2.11	0.00559	Adra1a/Abat/Kdr/Calca/Nos3	5
GO:1905606	regulation of presynapse assembly	BP	0.105	0.000701	0.00783	2.11	0.0056	Gpc6/Nlgn1/Ptprd/Lrrc4b	4
GO:0015849	organic acid transport	BP	0.0343	0.000716	0.00797	2.1	0.0057	Slc1a3/Grik1/Pla2g10/Slc13a5/Acsl6/Drd4/Abat/Rbp7/Lrp2/Grin2b/Slc7a2	11
GO:0009101	glycoprotein biosynthetic process	BP	0.0368	0.000727	0.00804	2.09	0.00575	St6gal2/St8sia2/Igf1/Itm2a/Tet1/St8sia4/Chst10/Gxylt2/Tmtc1/Soat1	10
GO:1904889	regulation of excitatory synapse assembly	BP	0.176	0.000729	0.00804	2.09	0.00575	Ptprd/Nptx1/Lrrc4b	3
GO:1905564	positive regulation of vascular endothelial cell proliferation	BP	0.176	0.000729	0.00804	2.09	0.00575	Mdk/Igf1/Itga4	3
GO:0010976	positive regulation of neuron projection development	BP	0.04	0.000735	0.00807	2.09	0.00577	Ptprz1/Hgf/Fez1/Dcc/Acsl6/Mdk/Lrrc7/Tenm3/Serpine2	9
GO:0051588	regulation of neurotransmitter transport	BP	0.0504	0.000749	0.00821	2.09	0.00587	Rims3/Adra1a/Drd4/Nlgn1/Edn3/P2rx2/Ppfia2	7
GO:0018108	peptidyl-tyrosine phosphorylation	BP	0.034	0.000772	0.00844	2.07	0.00603	Ptprz1/Hgf/Sfrp2/Angpt1/Spink1/Pkdcc/Adra1a/Igf1/Areg/Kdr/Cd44	11
GO:0070374	positive regulation of ERK1 and ERK2 cascade	BP	0.0396	0.000782	0.00849	2.07	0.00607	Angpt1/Dcc/Adra1a/Igf1/Npnt/Kdr/Cd44/Sema7a/Cxcl12	9
GO:0099504	synaptic vesicle cycle	BP	0.0396	0.000782	0.00849	2.07	0.00607	Syn2/Rims3/Adra1a/Drd4/Nlgn1/Cdh2/P2rx2/Ppfia2/Cadps	9
GO:0018212	peptidyl-tyrosine modification	BP	0.0336	0.000833	0.00901	2.05	0.00644	Ptprz1/Hgf/Sfrp2/Angpt1/Spink1/Pkdcc/Adra1a/Igf1/Areg/Kdr/Cd44	11
GO:0001704	formation of primary germ layer	BP	0.0583	0.000838	0.00902	2.04	0.00645	Sfrp2/Wnt11/Lef1/Nog/Hoxa11/Foxf1	6
GO:0021510	spinal cord development	BP	0.0583	0.000838	0.00902	2.04	0.00645	Vit/Dcc/Nog/Hoxd10/Dab1/Gdf7	6
GO:0051146	striated muscle cell differentiation	BP	0.0335	0.000854	0.00912	2.04	0.00652	AW551984/Ryr1/Col14a1/Sgcd/Adra1a/Igf1/Tmod2/Cdh2/Hopx/P2rx2/Cxcl12	11
GO:0051926	negative regulation of calcium ion transport	BP	0.0725	0.000856	0.00912	2.04	0.00652	Spink1/Drd4/Stc1/Calca/Nos3	5
GO:0060425	lung morphogenesis	BP	0.0725	0.000856	0.00912	2.04	0.00652	Hhip/Nog/Tbx2/Igf1/Foxf1	5
GO:0032230	positive regulation of synaptic transmission, GABAergic	BP	0.167	0.000868	0.00919	2.04	0.00657	Grik1/Adra1a/Nlgn1	3
GO:0097091	synaptic vesicle clustering	BP	0.167	0.000868	0.00919	2.04	0.00657	Syn2/Nlgn1/Cdh2	3
GO:0086003	cardiac muscle cell contraction	BP	0.0714	0.000913	0.00962	2.02	0.00688	Kcnd3/Sgcd/Scn4b/Scn1a/Stc1	5
GO:0050728	negative regulation of inflammatory response	BP	0.0486	0.000923	0.00969	2.01	0.00693	Acod1/Hgf/Pla2g10/Mdk/Igf1/Foxf1/Cd44	7
GO:0007612	learning	BP	0.0428	0.000933	0.00976	2.01	0.00698	Stra6/Nog/Drd4/Jph4/Chst10/Cacna1e/Grin2b/Slc8a3	8
GO:0014909	smooth muscle cell migration	BP	0.0566	0.000974	0.0101	1.99	0.00725	Cyp1b1/Mdk/Drd4/Igf1/Has2/Tert	6
GO:0015844	monoamine transport	BP	0.0566	0.000974	0.0101	1.99	0.00725	Maob/Slc6a2/Syt13/Abat/Cxcl12/Cadps	6
GO:0034765	regulation of ion transmembrane transport	BP	0.0281	0.001	0.0104	1.98	0.00744	Kcnb2/Nalcn/Kcnj3/Kcnd2/Kcna6/Kcnd3/Drd4/Scn4b/Nlgn1/Scn1a/Hecw2/Edn3/Kcnq5/Cacna1e	14
GO:0070989	oxidative demethylation	BP	0.158	0.00102	0.0105	1.98	0.00752	Cyp3a59/Cyp3a25/Tet1	3
GO:0071456	cellular response to hypoxia	BP	0.0561	0.00102	0.0105	1.98	0.00752	Kcnk3/Kcnd2/Ddah1/Cbs/Tert/Slc8a3	6
GO:0010092	specification of animal organ identity	BP	0.0952	0.00103	0.0105	1.98	0.00752	Wnt11/Hoxd11/Hoxa11/Lrp2	4
GO:0090175	regulation of establishment of planar polarity	BP	0.0952	0.00103	0.0105	1.98	0.00752	Sfrp2/Wnt11/Gpc3/Nkd1	4
GO:0099174	regulation of presynapse organization	BP	0.0952	0.00103	0.0105	1.98	0.00752	Gpc6/Nlgn1/Ptprd/Lrrc4b	4
GO:0061035	regulation of cartilage development	BP	0.0694	0.00104	0.0106	1.98	0.00755	Mdk/Nog/Pkdcc/Hoxd11/Hoxa11	5
GO:2000179	positive regulation of neural precursor cell proliferation	BP	0.0694	0.00104	0.0106	1.98	0.00755	Gli1/Mdk/Nog/Igf1/Lrp2	5
GO:0001508	action potential	BP	0.0476	0.00104	0.0106	1.98	0.00755	Kcnd2/Kcnd3/Adra1a/Scn4b/Scn1a/P2rx2/Grin2b	7
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	BP	0.0307	0.00109	0.011	1.96	0.00784	Sfrp2/Lef1/Cd109/Nog/Fst/Rnf165/Npnt/Kdr/Gpc3/Lrp2/Btbd11/Gdf7	12
GO:0008202	steroid metabolic process	BP	0.0325	0.00109	0.011	1.96	0.00784	Apob/Cyp3a59/Cyp1b1/Cyp3a25/Hmgcs2/Nr5a2/Igf1/Cyp7b1/Ednrb/Chst10/Soat1	11
GO:0045055	regulated exocytosis	BP	0.0348	0.00109	0.011	1.96	0.00785	Syn2/Rims3/Adra1a/Drd4/Syt13/Nlgn1/Foxf1/P2rx2/Ppfia2/Cadps	10
GO:1905330	regulation of morphogenesis of an epithelium	BP	0.0685	0.0011	0.0111	1.96	0.00792	Hgf/Mdk/Nog/Tbx2/Nkd1	5
GO:0008406	gonad development	BP	0.0375	0.00116	0.0115	1.94	0.00824	Sfrp2/Angpt1/Fst/Kdr/Hoxa11/Hoxa10/Nos3/Lrp2/Mmp2	9
GO:1903510	mucopolysaccharide metabolic process	BP	0.0676	0.00117	0.0117	1.93	0.00835	Angpt1/Spock2/Ednrb/Cd44/Has2	5
GO:0050965	detection of temperature stimulus involved in sensory perception of pain	BP	0.15	0.00119	0.0118	1.93	0.00841	Calca/Ano1/Cxcl12	3
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	BP	0.15	0.00119	0.0118	1.93	0.00841	Scn1a/Grin2b/Cxcl12	3
GO:1903236	regulation of leukocyte tethering or rolling	BP	0.15	0.00119	0.0118	1.93	0.00841	Itga4/Chst2/Cxcl12	3
GO:1903037	regulation of leukocyte cell-cell adhesion	BP	0.0321	0.00122	0.012	1.92	0.0086	Ihh/Efnb3/Lef1/Cd83/Mdk/Igf1/Itga4/Chst2/Cd44/Has2/Cxcl12	11
GO:0010464	regulation of mesenchymal cell proliferation	BP	0.0909	0.00123	0.012	1.92	0.0086	Ihh/Wnt11/Kdr/Foxf1	4
GO:0048645	animal organ formation	BP	0.0667	0.00125	0.0122	1.91	0.00872	Wnt11/Nog/Hoxd11/Hoxa11/Lrp2	5
GO:0019722	calcium-mediated signaling	BP	0.0408	0.00126	0.0122	1.91	0.00876	Sgcd/Drd4/Nr5a2/Igf1/Slc24a4/Kdr/Ednrb/Ptgfr	8
GO:0030900	forebrain development	BP	0.0302	0.00126	0.0122	1.91	0.00876	Gli1/Lef1/Sema5a/Mdk/Nog/Cdh2/Dnah5/Dab1/Lrp2/Sema7a/Cxcl12/Gdf7	12
GO:0046660	female sex differentiation	BP	0.0461	0.00126	0.0122	1.91	0.00876	Stra6/Angpt1/Fst/Kdr/Nos3/Lrp2/Mmp2	7
GO:0055017	cardiac muscle tissue growth	BP	0.0536	0.0013	0.0125	1.9	0.00894	Gli1/Col14a1/Nog/Adra1a/Tbx2/Igf1	6
GO:0045137	development of primary sexual characteristics	BP	0.0369	0.0013	0.0125	1.9	0.00894	Sfrp2/Angpt1/Fst/Kdr/Hoxa11/Hoxa10/Nos3/Lrp2/Mmp2	9
GO:0050905	neuromuscular process	BP	0.0404	0.00134	0.0129	1.89	0.00924	Ankfn1/Stra6/Slc1a3/Hoxd10/Jph4/Scn1a/Grin2b/Slc8a3	8
GO:2001234	negative regulation of apoptotic signaling pathway	BP	0.0366	0.00137	0.0131	1.88	0.0094	Hgf/Sfrp2/Nog/Igf1/Cd44/Tert/Bok/Cxcl12/Agap2	9
GO:0001976	nervous system process involved in regulation of systemic arterial blood pressure	BP	0.143	0.00138	0.0131	1.88	0.0094	Adra1a/Calca/P2rx2	3
GO:0032332	positive regulation of chondrocyte differentiation	BP	0.143	0.00138	0.0131	1.88	0.0094	Pkdcc/Hoxd11/Hoxa11	3
GO:0097107	postsynaptic density assembly	BP	0.143	0.00138	0.0131	1.88	0.0094	Ptprd/Nptx1/Lrrc4b	3
GO:0006029	proteoglycan metabolic process	BP	0.0649	0.0014	0.0132	1.88	0.00944	Ihh/Col11a1/Igf1/Spock2/Chst10	5
GO:0043113	receptor clustering	BP	0.0649	0.0014	0.0132	1.88	0.00944	Lrrc7/Nlgn1/Itga4/Cdh2/Grin2b	5
GO:0060976	coronary vasculature development	BP	0.0649	0.0014	0.0132	1.88	0.00944	Angpt1/Sgcd/Gpc3/Lrp2/Kif7	5
GO:0098661	inorganic anion transmembrane transport	BP	0.0649	0.0014	0.0132	1.88	0.00944	Slc1a3/Slc12a8/Ano2/Ano1/Gabra4	5
GO:0017157	regulation of exocytosis	BP	0.0364	0.00141	0.0132	1.88	0.00946	Rims3/Adra1a/Drd4/Syt13/Nlgn1/Foxf1/P2rx2/Ppfia2/Cadps	9
GO:0022409	positive regulation of cell-cell adhesion	BP	0.0336	0.00145	0.0135	1.87	0.00967	Ihh/Efnb3/Lef1/Cd83/Mdk/Igf1/Itga4/Chst2/Cd44/Has2	10
GO:0002691	regulation of cellular extravasation	BP	0.087	0.00145	0.0135	1.87	0.00968	Mdk/Itga4/Chst2/Cxcl12	4
GO:0098656	anion transmembrane transport	BP	0.0396	0.00153	0.0142	1.85	0.0102	Slc1a3/Slc13a5/Slc12a8/Ano2/Lrp2/Ano1/Slc7a2/Gabra4	8
GO:0015711	organic anion transport	BP	0.0312	0.00154	0.0143	1.85	0.0102	Car4/Slc1a3/Grik1/Pla2g10/Slc13a5/Slc2a3/Drd4/Abat/Lrp2/Grin2b/Slc7a2	11
GO:0043616	keratinocyte proliferation	BP	0.0851	0.00157	0.0145	1.84	0.0104	Cd109/Mdk/Fst/Has2	4
GO:0045667	regulation of osteoblast differentiation	BP	0.0443	0.00158	0.0145	1.84	0.0104	Gli1/Sfrp2/Nog/Igf1/Areg/Npnt/Nell1	7
GO:0060080	inhibitory postsynaptic potential	BP	0.136	0.00159	0.0145	1.84	0.0104	Grik1/Drd4/Abat	3
GO:0060749	mammary gland alveolus development	BP	0.136	0.00159	0.0145	1.84	0.0104	Areg/Foxf1/Agap2	3
GO:0061377	mammary gland lobule development	BP	0.136	0.00159	0.0145	1.84	0.0104	Areg/Foxf1/Agap2	3
GO:0030308	negative regulation of cell growth	BP	0.0392	0.00162	0.0148	1.83	0.0106	Sfrp2/Map2/Wnt11/Tro/Sema5a/Sema5b/Sema7a/Serpine2	8
GO:0030517	negative regulation of axon extension	BP	0.0833	0.0017	0.0155	1.81	0.0111	Map2/Sema5a/Sema5b/Sema7a	4
GO:0099003	vesicle-mediated transport in synapse	BP	0.0354	0.00171	0.0155	1.81	0.0111	Syn2/Rims3/Adra1a/Drd4/Nlgn1/Cdh2/P2rx2/Ppfia2/Cadps	9
GO:0003208	cardiac ventricle morphogenesis	BP	0.0617	0.00176	0.0159	1.8	0.0114	Col11a1/Sfrp2/Nog/Foxf1/Lrp2	5
GO:0099173	postsynapse organization	BP	0.0386	0.00178	0.0161	1.79	0.0115	Gap43/Nlgn1/Ptprd/Nptx1/Lrrc4b/Cdh2/Ppfia2/Grin2b	8
GO:0045765	regulation of angiogenesis	BP	0.0326	0.0018	0.0162	1.79	0.0116	Cyp1b1/Hgf/Sfrp2/Hhip/Sema5a/Mdk/Ddah1/Kdr/Nos3/Tert	10
GO:0090257	regulation of muscle system process	BP	0.0352	0.0018	0.0162	1.79	0.0116	Ryr1/Adra1a/Igf1/Npnt/Abat/Stc1/Calca/Nos3/Slc8a3	9
GO:0042053	regulation of dopamine metabolic process	BP	0.13	0.00181	0.0162	1.79	0.0116	Maob/Drd4/Abat	3
GO:0050961	detection of temperature stimulus involved in sensory perception	BP	0.13	0.00181	0.0162	1.79	0.0116	Calca/Ano1/Cxcl12	3
GO:0071526	semaphorin-plexin signaling pathway	BP	0.0816	0.00184	0.0163	1.79	0.0117	Sema5a/Sema5b/Plxnb1/Sema7a	4
GO:0007498	mesoderm development	BP	0.05	0.00184	0.0163	1.79	0.0117	Sfrp2/Wnt11/Lef1/Nog/Hoxa11/Foxf1	6
GO:0014812	muscle cell migration	BP	0.05	0.00184	0.0163	1.79	0.0117	Cyp1b1/Mdk/Drd4/Igf1/Has2/Tert	6
GO:0045123	cellular extravasation	BP	0.061	0.00186	0.0164	1.78	0.0117	Mdk/Itga4/Chst2/Cxcl12/Podxl2	5
GO:0051963	regulation of synapse assembly	BP	0.0496	0.00192	0.017	1.77	0.0121	Gpc6/St8sia2/Nlgn1/Ptprd/Nptx1/Lrrc4b	6
GO:0050954	sensory perception of mechanical stimulus	BP	0.0323	0.00193	0.017	1.77	0.0122	Col11a1/Slc1a3/Igf1/Tub/Scn1a/P2rx2/Lrp2/Grin2b/Serpine2/Cxcl12	10
GO:0006937	regulation of muscle contraction	BP	0.0427	0.00195	0.0171	1.77	0.0122	Ryr1/Adra1a/Npnt/Abat/Stc1/Calca/Slc8a3	7
GO:0007338	single fertilization	BP	0.0427	0.00195	0.0171	1.77	0.0122	Pla2g10/Spink1/Hoxd10/Hoxd11/Hoxa11/Hoxa10/Hoxd9	7
GO:0055021	regulation of cardiac muscle tissue growth	BP	0.0602	0.00196	0.0171	1.77	0.0122	Gli1/Col14a1/Nog/Tbx2/Igf1	5
GO:1901342	regulation of vasculature development	BP	0.0322	0.00198	0.0172	1.76	0.0123	Cyp1b1/Hgf/Sfrp2/Hhip/Sema5a/Mdk/Ddah1/Kdr/Nos3/Tert	10
GO:0003197	endocardial cushion development	BP	0.08	0.00198	0.0172	1.76	0.0123	Nog/Tbx2/Foxf1/Nos3	4
GO:0060419	heart growth	BP	0.0492	0.002	0.0174	1.76	0.0124	Gli1/Col14a1/Nog/Adra1a/Tbx2/Igf1	6
GO:0030879	mammary gland development	BP	0.0424	0.00202	0.0175	1.76	0.0125	Lef1/Tbx2/Igf1/Areg/Foxf1/Hoxd9/Agap2	7
GO:0030903	notochord development	BP	0.125	0.00205	0.0176	1.75	0.0126	Gli1/Wnt11/Nog	3
GO:0031643	positive regulation of myelination	BP	0.125	0.00205	0.0176	1.75	0.0126	Hgf/Igf1/Wasf3	3
GO:0048333	mesodermal cell differentiation	BP	0.125	0.00205	0.0176	1.75	0.0126	Sfrp2/Hoxa11/Foxf1	3
GO:0006809	nitric oxide biosynthetic process	BP	0.0595	0.00206	0.0177	1.75	0.0126	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2	5
GO:0010631	epithelial cell migration	BP	0.0319	0.00207	0.0177	1.75	0.0127	Cyp1b1/Angpt1/Sema5a/Igf1/Kdr/Stc1/Calca/Nos3/Has2/Evl	10
GO:0010466	negative regulation of peptidase activity	BP	0.0344	0.00211	0.018	1.75	0.0128	Hgf/Sfrp2/Spink1/Cd109/Igf1/Gpc3/Tfpi/Cd44/Serpine2	9
GO:0090132	epithelium migration	BP	0.0317	0.00217	0.0184	1.73	0.0132	Cyp1b1/Angpt1/Sema5a/Igf1/Kdr/Stc1/Calca/Nos3/Has2/Evl	10
GO:0051954	positive regulation of amine transport	BP	0.0769	0.00229	0.0193	1.71	0.0138	Grik1/Abat/Grin2b/Cxcl12	4
GO:0007263	nitric oxide mediated signal transduction	BP	0.12	0.00232	0.0193	1.71	0.0138	Spink1/Cbs/Nos3	3
GO:0010884	positive regulation of lipid storage	BP	0.12	0.00232	0.0193	1.71	0.0138	Apob/Pla2g10/Vstm2a	3
GO:0010996	response to auditory stimulus	BP	0.12	0.00232	0.0193	1.71	0.0138	Stra6/Slc1a3/Mdk	3
GO:0042069	regulation of catecholamine metabolic process	BP	0.12	0.00232	0.0193	1.71	0.0138	Maob/Drd4/Abat	3
GO:0101023	vascular endothelial cell proliferation	BP	0.12	0.00232	0.0193	1.71	0.0138	Mdk/Igf1/Itga4	3
GO:1905562	regulation of vascular endothelial cell proliferation	BP	0.12	0.00232	0.0193	1.71	0.0138	Mdk/Igf1/Itga4	3
GO:0050730	regulation of peptidyl-tyrosine phosphorylation	BP	0.0338	0.00233	0.0194	1.71	0.0139	Ptprz1/Hgf/Sfrp2/Angpt1/Spink1/Adra1a/Igf1/Areg/Cd44	9
GO:0032890	regulation of organic acid transport	BP	0.0575	0.00241	0.0199	1.7	0.0143	Grik1/Pla2g10/Acsl6/Abat/Grin2b	5
GO:0060411	cardiac septum morphogenesis	BP	0.0575	0.00241	0.0199	1.7	0.0143	Wnt11/Nog/Tbx2/Nos3/Lrp2	5
GO:0032355	response to estradiol	BP	0.0755	0.00245	0.0202	1.69	0.0145	Areg/Nos3/Ptgfr/Mmp2	4
GO:0070169	positive regulation of biomineral tissue development	BP	0.0755	0.00245	0.0202	1.69	0.0145	Wnt6/Pkdcc/Osr2/Nell1	4
GO:0001738	morphogenesis of a polarized epithelium	BP	0.0568	0.00253	0.0207	1.68	0.0148	Sfrp2/Wnt11/Gpc3/Nkd1/Foxf1	5
GO:0003281	ventricular septum development	BP	0.0568	0.00253	0.0207	1.68	0.0148	Stra6/Wnt11/Nog/Nos3/Lrp2	5
GO:0051937	catecholamine transport	BP	0.0568	0.00253	0.0207	1.68	0.0148	Slc6a2/Syt13/Abat/Cxcl12/Cadps	5
GO:0030282	bone mineralization	BP	0.0469	0.00255	0.0208	1.68	0.0149	Wnt11/Pkdcc/Igf1/Gpc3/Osr2/Nell1	6
GO:0048639	positive regulation of developmental growth	BP	0.0364	0.0026	0.021	1.68	0.015	Gli1/Sema5a/Tbx2/Igf1/Cpne5/Hopx/Sema7a/Cxcl12	8
GO:0060065	uterus development	BP	0.115	0.0026	0.021	1.68	0.015	Stra6/Hoxa11/Hoxa10	3
GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	BP	0.115	0.0026	0.021	1.68	0.015	Mdk/Itga4/Chst2	3
GO:2000050	regulation of non-canonical Wnt signaling pathway	BP	0.115	0.0026	0.021	1.68	0.015	Sfrp2/Gpc3/Nkd1	3
GO:0007617	mating behavior	BP	0.0741	0.00263	0.021	1.68	0.015	Drd4/Abat/Ednrb/Serpine2	4
GO:0010883	regulation of lipid storage	BP	0.0741	0.00263	0.021	1.68	0.015	Apob/Pla2g10/Mest/Vstm2a	4
GO:0032330	regulation of chondrocyte differentiation	BP	0.0741	0.00263	0.021	1.68	0.015	Mdk/Pkdcc/Hoxd11/Hoxa11	4
GO:0099054	presynapse assembly	BP	0.0741	0.00263	0.021	1.68	0.015	Gpc6/Nlgn1/Ptprd/Lrrc4b	4
GO:0033674	positive regulation of kinase activity	BP	0.0276	0.00263	0.021	1.68	0.015	Epha8/Angpt1/Adra1a/Drd4/Igf1/Areg/Kdr/Dab1/Calca/Edn3/Ccdc88a/Agap2	12
GO:0030048	actin filament-based movement	BP	0.0465	0.00265	0.0211	1.68	0.0151	Kcnd3/Sgcd/Scn4b/Scn1a/Stc1/Evl	6
GO:0050805	negative regulation of synaptic transmission	BP	0.0562	0.00266	0.0211	1.68	0.0151	Grik1/Grid2ip/Drd4/Celf4/Gnai1	5
GO:0006941	striated muscle contraction	BP	0.0402	0.00272	0.0215	1.67	0.0154	Kcnd3/Sgcd/Adra1a/Scn4b/Scn1a/Stc1/Slc8a3	7
GO:0070997	neuron death	BP	0.0274	0.00278	0.0218	1.66	0.0156	Ptprz1/Angpt1/Dcc/St8sia2/Mdk/Igf1/Kdr/Dpysl4/Grin2b/Tert/Bok/Agap2	12
GO:0006835	dicarboxylic acid transport	BP	0.0556	0.00279	0.0218	1.66	0.0156	Slc1a3/Slc13a5/Abat/Lrp2/Grin2b	5
GO:0019915	lipid storage	BP	0.0556	0.00279	0.0218	1.66	0.0156	Apob/Pla2g10/Mest/Soat1/Vstm2a	5
GO:0031016	pancreas development	BP	0.0556	0.00279	0.0218	1.66	0.0156	Ihh/Nr5a2/Igf1/Cdh2/Foxf1	5
GO:0046209	nitric oxide metabolic process	BP	0.0556	0.00279	0.0218	1.66	0.0156	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2	5
GO:0042552	myelination	BP	0.04	0.00281	0.0218	1.66	0.0156	Ptprz1/Hgf/Igf1/Epb41l3/Cdh2/Wasf3/Slc8a3	7
GO:0003044	regulation of systemic arterial blood pressure mediated by a chemical signal	BP	0.0727	0.00281	0.0218	1.66	0.0156	Adra1a/Ednrb/Nos3/Edn3	4
GO:0048546	digestive tract morphogenesis	BP	0.0727	0.00281	0.0218	1.66	0.0156	Ihh/Stra6/Sfrp2/Foxf1	4
GO:0015740	C4-dicarboxylate transport	BP	0.111	0.0029	0.0224	1.65	0.016	Slc1a3/Slc13a5/Abat	3
GO:0016048	detection of temperature stimulus	BP	0.111	0.0029	0.0224	1.65	0.016	Calca/Ano1/Cxcl12	3
GO:0048843	negative regulation of axon extension involved in axon guidance	BP	0.111	0.0029	0.0224	1.65	0.016	Sema5a/Sema5b/Sema7a	3
GO:0060420	regulation of heart growth	BP	0.0549	0.00293	0.0226	1.65	0.0161	Gli1/Col14a1/Nog/Tbx2/Igf1	5
GO:0036294	cellular response to decreased oxygen levels	BP	0.0455	0.00297	0.0228	1.64	0.0163	Kcnk3/Kcnd2/Ddah1/Cbs/Tert/Slc8a3	6
GO:0060048	cardiac muscle contraction	BP	0.0455	0.00297	0.0228	1.64	0.0163	Kcnd3/Sgcd/Adra1a/Scn4b/Scn1a/Stc1	6
GO:0001974	blood vessel remodeling	BP	0.0714	0.003	0.0229	1.64	0.0164	Igf1/Itga4/Cbs/Nos3	4
GO:0007588	excretion	BP	0.0714	0.003	0.0229	1.64	0.0164	Mdk/Adra1a/Ednrb/Stc1	4
GO:0043536	positive regulation of blood vessel endothelial cell migration	BP	0.0714	0.003	0.0229	1.64	0.0164	Angpt1/Igf1/Kdr/Nos3	4
GO:1903035	negative regulation of response to wounding	BP	0.0543	0.00307	0.0233	1.63	0.0167	Cd109/Mdk/Abat/Tfpi/Serpine2	5
GO:2001057	reactive nitrogen species metabolic process	BP	0.0543	0.00307	0.0233	1.63	0.0167	Cyp1b1/Igf1/Ddah1/Nos3/Slc7a2	5
GO:0008366	axon ensheathment	BP	0.0393	0.00309	0.0233	1.63	0.0167	Ptprz1/Hgf/Igf1/Epb41l3/Cdh2/Wasf3/Slc8a3	7
GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	BP	0.0352	0.00314	0.0237	1.63	0.0169	Vipr2/Adra1a/Drd4/Calca/Gnai1/Ptgfr/Adgrl4/Npr3	8
GO:0007369	gastrulation	BP	0.0391	0.00318	0.0238	1.62	0.017	Sfrp2/Wnt11/Lef1/Nog/Hoxa11/Foxf1/Osr2	7
GO:0060402	calcium ion transport into cytosol	BP	0.0391	0.00318	0.0238	1.62	0.017	Ryr1/Adra1a/Slc24a4/Calca/Cacna1e/Grin2b/Slc8a3	7
GO:0031646	positive regulation of nervous system process	BP	0.0702	0.0032	0.0238	1.62	0.017	Hgf/Igf1/Abat/Wasf3	4
GO:0035567	non-canonical Wnt signaling pathway	BP	0.0702	0.0032	0.0238	1.62	0.017	Sfrp2/Wnt11/Gpc3/Nkd1	4
GO:0086001	cardiac muscle cell action potential	BP	0.0702	0.0032	0.0238	1.62	0.017	Kcnd2/Kcnd3/Scn4b/Scn1a	4
GO:0010959	regulation of metal ion transport	BP	0.0269	0.00322	0.0238	1.62	0.017	Spink1/Drd4/Scn4b/Igf1/Jph4/Hecw2/Stc1/Calca/Nos3/Edn3/Serpine2/Cxcl12	12
GO:0033688	regulation of osteoblast proliferation	BP	0.107	0.00322	0.0238	1.62	0.017	Plxnb1/Nell1/Npr3	3
GO:0043931	ossification involved in bone maturation	BP	0.107	0.00322	0.0238	1.62	0.017	Ryr1/Igf1/Plxnb1	3
GO:0061484	hematopoietic stem cell homeostasis	BP	0.107	0.00322	0.0238	1.62	0.017	Crispld1/Gprasp2/Emcn	3
GO:0030595	leukocyte chemotaxis	BP	0.0351	0.00323	0.0238	1.62	0.017	Cxcl15/Mdk/Ptpro/Cyp7b1/Ednrb/Calca/Edn3/Cxcl12	8
GO:0043542	endothelial cell migration	BP	0.0351	0.00323	0.0238	1.62	0.017	Cyp1b1/Angpt1/Sema5a/Igf1/Kdr/Stc1/Calca/Nos3	8
GO:0048660	regulation of smooth muscle cell proliferation	BP	0.0389	0.00328	0.0241	1.62	0.0173	Vipr2/Drd4/Igf1/Nos3/Tert/Mmp2/Npr3	7
GO:0050806	positive regulation of synaptic transmission	BP	0.0299	0.00337	0.0246	1.61	0.0176	Slc1a3/Grik1/Gria4/Nog/Rims3/Adra1a/Nlgn1/Grin2b/Serpine2/Slc8a3	10
GO:0030203	glycosaminoglycan metabolic process	BP	0.0532	0.00337	0.0246	1.61	0.0176	Angpt1/Spock2/Ednrb/Cd44/Has2	5
GO:0051899	membrane depolarization	BP	0.0532	0.00337	0.0246	1.61	0.0176	Grik1/Scn4b/Scn1a/Kdr/Bok	5
GO:0060041	retina development in camera-type eye	BP	0.0387	0.00339	0.0246	1.61	0.0176	Ndp/Cyp1b1/Ihh/Sdk2/Tub/Lamc3/Celf4	7
GO:0015872	dopamine transport	BP	0.069	0.00341	0.0247	1.61	0.0176	Slc6a2/Syt13/Abat/Cxcl12	4
GO:0021587	cerebellum morphogenesis	BP	0.069	0.00341	0.0247	1.61	0.0176	Gli1/Dab1/Cbs/Serpine2	4
GO:0042311	vasodilation	BP	0.069	0.00341	0.0247	1.61	0.0176	Kdr/Ednrb/Calca/Npr3	4
GO:1901214	regulation of neuron death	BP	0.0281	0.00344	0.0248	1.6	0.0178	Ptprz1/Angpt1/Dcc/St8sia2/Mdk/Igf1/Kdr/Grin2b/Tert/Bok/Agap2	11
GO:0045685	regulation of glial cell differentiation	BP	0.0526	0.00353	0.0254	1.6	0.0182	Ptprz1/Mdk/Nog/Dab1/Serpine2	5
GO:0001759	organ induction	BP	0.103	0.00356	0.0256	1.59	0.0183	Wnt11/Hoxd11/Hoxa11	3
GO:0030318	melanocyte differentiation	BP	0.103	0.00356	0.0256	1.59	0.0183	Adamts20/Ednrb/Edn3	3
GO:0001935	endothelial cell proliferation	BP	0.0383	0.0036	0.0257	1.59	0.0184	Sema5a/Mdk/Igf1/Itga4/Kdr/Calca/Cxcl12	7
GO:0030199	collagen fibril organization	BP	0.0678	0.00363	0.0258	1.59	0.0184	Cyp1b1/Col11a1/Sfrp2/Col14a1	4
GO:0031279	regulation of cyclase activity	BP	0.0678	0.00363	0.0258	1.59	0.0184	Vipr2/Calca/Nos3/Npr3	4
GO:0045778	positive regulation of ossification	BP	0.0678	0.00363	0.0258	1.59	0.0184	Pkdcc/Calca/Osr2/Nell1	4
GO:1903793	positive regulation of anion transport	BP	0.0678	0.00363	0.0258	1.59	0.0184	Grik1/Pla2g10/Abat/Grin2b	4
GO:0030177	positive regulation of Wnt signaling pathway	BP	0.0432	0.00383	0.0272	1.57	0.0194	Sfrp2/Lef1/Sema5a/Gpc3/Nkd1/Tert	6
GO:0002028	regulation of sodium ion transport	BP	0.0515	0.00386	0.0272	1.57	0.0195	Drd4/Scn4b/Hecw2/Nos3/Serpine2	5
GO:0097479	synaptic vesicle localization	BP	0.0667	0.00386	0.0272	1.57	0.0195	Syn2/Map2/Nlgn1/Cdh2	4
GO:0048596	embryonic camera-type eye morphogenesis	BP	0.1	0.00393	0.0275	1.56	0.0197	Ihh/Stra6/Tbx2	3
GO:0051957	positive regulation of amino acid transport	BP	0.1	0.00393	0.0275	1.56	0.0197	Grik1/Abat/Grin2b	3
GO:0060563	neuroepithelial cell differentiation	BP	0.1	0.00393	0.0275	1.56	0.0197	Wnt11/Lef1/Cdh2	3
GO:0070977	bone maturation	BP	0.1	0.00393	0.0275	1.56	0.0197	Ryr1/Igf1/Plxnb1	3
GO:0042632	cholesterol homeostasis	BP	0.051	0.00403	0.0281	1.55	0.0201	Apob/Pla2g10/Nr5a2/Cyp7b1/Soat1	5
GO:0070252	actin-mediated cell contraction	BP	0.051	0.00403	0.0281	1.55	0.0201	Kcnd3/Sgcd/Scn4b/Scn1a/Stc1	5
GO:0046942	carboxylic acid transport	BP	0.0311	0.00403	0.0281	1.55	0.0201	Slc1a3/Grik1/Pla2g10/Slc13a5/Drd4/Abat/Lrp2/Grin2b/Slc7a2	9
GO:0010656	negative regulation of muscle cell apoptotic process	BP	0.0656	0.00409	0.0284	1.55	0.0203	Sfrp2/Gria4/Mdk/Igf1	4
GO:0099172	presynapse organization	BP	0.0656	0.00409	0.0284	1.55	0.0203	Gpc6/Nlgn1/Ptprd/Lrrc4b	4
GO:0048659	smooth muscle cell proliferation	BP	0.0372	0.00417	0.0288	1.54	0.0206	Vipr2/Drd4/Igf1/Nos3/Tert/Mmp2/Npr3	7
GO:0055092	sterol homeostasis	BP	0.0505	0.00421	0.029	1.54	0.0208	Apob/Pla2g10/Nr5a2/Cyp7b1/Soat1	5
GO:0048675	axon extension	BP	0.0423	0.00426	0.0293	1.53	0.021	Map2/Sema5a/Sema5b/Edn3/Sema7a/Cxcl12	6
GO:0003085	negative regulation of systemic arterial blood pressure	BP	0.0968	0.00432	0.0296	1.53	0.0211	Adra1a/Kdr/Calca	3
GO:0050951	sensory perception of temperature stimulus	BP	0.0968	0.00432	0.0296	1.53	0.0211	Calca/Ano1/Cxcl12	3
GO:0001736	establishment of planar polarity	BP	0.0645	0.00434	0.0296	1.53	0.0211	Sfrp2/Wnt11/Gpc3/Nkd1	4
GO:0021575	hindbrain morphogenesis	BP	0.0645	0.00434	0.0296	1.53	0.0211	Gli1/Dab1/Cbs/Serpine2	4
GO:0051339	regulation of lyase activity	BP	0.0645	0.00434	0.0296	1.53	0.0211	Vipr2/Calca/Nos3/Npr3	4
GO:0051932	synaptic transmission, GABAergic	BP	0.0645	0.00434	0.0296	1.53	0.0211	Grik1/Adra1a/Nlgn1/Gabra4	4
GO:0043524	negative regulation of neuron apoptotic process	BP	0.0368	0.00441	0.03	1.52	0.0215	Ptprz1/Angpt1/Mdk/Kdr/Tert/Bok/Agap2	7
GO:0010632	regulation of epithelial cell migration	BP	0.0332	0.0045	0.0305	1.52	0.0218	Angpt1/Sema5a/Igf1/Kdr/Stc1/Nos3/Has2/Evl	8
GO:0045664	regulation of neuron differentiation	BP	0.0332	0.0045	0.0305	1.52	0.0218	Sfrp2/Fez1/Nlgn1/Rgs6/Ednrb/Dab1/Cxcl12/Gdf7	8
GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	BP	0.0495	0.00458	0.0308	1.51	0.022	Adra1a/Ednrb/Calca/Ano1/Npr3	5
GO:0060021	roof of mouth development	BP	0.0495	0.00458	0.0308	1.51	0.022	Wnt11/Lef1/Pkdcc/Tbx2/Osr2	5
GO:0007164	establishment of tissue polarity	BP	0.0635	0.0046	0.0309	1.51	0.0221	Sfrp2/Wnt11/Gpc3/Nkd1	4
GO:0050727	regulation of inflammatory response	BP	0.0285	0.00467	0.0313	1.51	0.0224	Acod1/Hgf/Pla2g10/Mdk/Igf1/Ednrb/Foxf1/Cd44/Sema7a/Slc7a2	10
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	BP	0.0365	0.00467	0.0313	1.51	0.0224	Ptprz1/Hgf/Angpt1/Adra1a/Igf1/Areg/Cd44	7
GO:0003416	endochondral bone growth	BP	0.0938	0.00473	0.0315	1.5	0.0225	Kdr/Evc/Stc1	3
GO:0060977	coronary vasculature morphogenesis	BP	0.0938	0.00473	0.0315	1.5	0.0225	Angpt1/Sgcd/Lrp2	3
GO:0098703	calcium ion import across plasma membrane	BP	0.0938	0.00473	0.0315	1.5	0.0225	Slc24a4/Cacna1e/Slc8a3	3
GO:0006054	N-acetylneuraminate metabolic process	BP	0.2	0.00481	0.0316	1.5	0.0226	St6gal2/Npl	2
GO:0006527	arginine catabolic process	BP	0.2	0.00481	0.0316	1.5	0.0226	Ddah1/Nos3	2
GO:0060385	axonogenesis involved in innervation	BP	0.2	0.00481	0.0316	1.5	0.0226	Itga4/Nptx1	2
GO:0097105	presynaptic membrane assembly	BP	0.2	0.00481	0.0316	1.5	0.0226	Nlgn1/Ptprd	2
GO:0097119	postsynaptic density protein 95 clustering	BP	0.2	0.00481	0.0316	1.5	0.0226	Nlgn1/Cdh2	2
GO:2000807	regulation of synaptic vesicle clustering	BP	0.2	0.00481	0.0316	1.5	0.0226	Nlgn1/Cdh2	2
GO:1904705	regulation of vascular associated smooth muscle cell proliferation	BP	0.0625	0.00486	0.0319	1.5	0.0228	Drd4/Igf1/Tert/Mmp2	4
GO:0007204	positive regulation of cytosolic calcium ion concentration	BP	0.0282	0.00495	0.0324	1.49	0.0232	Ryr1/Adra1a/Slc24a4/Kdr/Ednrb/Calca/Ptgfr/Cacna1e/Grin2b/Slc8a3	10
GO:0010469	regulation of signaling receptor activity	BP	0.0408	0.00503	0.0329	1.48	0.0235	Begain/Nog/Nlgn1/Slc24a4/Areg/Nptx1	6
GO:0003229	ventricular cardiac muscle tissue development	BP	0.0615	0.00514	0.0335	1.47	0.024	Col11a1/Col14a1/Nog/Lrp2	4
GO:1902656	calcium ion import into cytosol	BP	0.0909	0.00516	0.0336	1.47	0.024	Slc24a4/Cacna1e/Slc8a3	3
GO:0070167	regulation of biomineral tissue development	BP	0.0481	0.00518	0.0337	1.47	0.0241	Wnt6/Pkdcc/Nos3/Osr2/Nell1	5
GO:0071453	cellular response to oxygen levels	BP	0.0405	0.0052	0.0337	1.47	0.0241	Kcnk3/Kcnd2/Ddah1/Cbs/Tert/Slc8a3	6
GO:0045860	positive regulation of protein kinase activity	BP	0.0279	0.00534	0.0346	1.46	0.0247	Angpt1/Adra1a/Drd4/Igf1/Areg/Dab1/Calca/Edn3/Ccdc88a/Agap2	10
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	BP	0.0476	0.00539	0.0349	1.46	0.0249	Hgf/Sfrp2/Igf1/Tert/Agap2	5
GO:0051047	positive regulation of secretion	BP	0.0264	0.00544	0.0351	1.46	0.0251	Grik1/Pla2g10/Igf1/Nlgn1/Abat/Ednrb/Edn3/Grin2b/Ano1/Cxcl12/Cadps	11
GO:0009953	dorsal/ventral pattern formation	BP	0.0472	0.00561	0.0359	1.44	0.0257	Gli1/Hhip/Nog/Hoxd11/Hoxa11	5
GO:0003156	regulation of animal organ formation	BP	0.0882	0.00561	0.0359	1.44	0.0257	Wnt11/Hoxd11/Hoxa11	3
GO:0048799	animal organ maturation	BP	0.0882	0.00561	0.0359	1.44	0.0257	Ryr1/Igf1/Plxnb1	3
GO:1990874	vascular associated smooth muscle cell proliferation	BP	0.0597	0.00572	0.0365	1.44	0.0261	Drd4/Igf1/Tert/Mmp2	4
GO:0006821	chloride transport	BP	0.0467	0.00584	0.0365	1.44	0.0261	Slc1a3/Slc12a8/Ano2/Ano1/Gabra4	5
GO:0003139	secondary heart field specification	BP	0.182	0.00584	0.0365	1.44	0.0261	Wnt11/Lrp2	2
GO:0010749	regulation of nitric oxide mediated signal transduction	BP	0.182	0.00584	0.0365	1.44	0.0261	Spink1/Cbs	2
GO:0021940	positive regulation of cerebellar granule cell precursor proliferation	BP	0.182	0.00584	0.0365	1.44	0.0261	Gli1/Igf1	2
GO:0030202	heparin metabolic process	BP	0.182	0.00584	0.0365	1.44	0.0261	Angpt1/Ednrb	2
GO:0033689	negative regulation of osteoblast proliferation	BP	0.182	0.00584	0.0365	1.44	0.0261	Plxnb1/Nell1	2
GO:0036302	atrioventricular canal development	BP	0.182	0.00584	0.0365	1.44	0.0261	Tbx2/Has2	2
GO:0060405	regulation of penile erection	BP	0.182	0.00584	0.0365	1.44	0.0261	Drd4/Ednrb	2
GO:0061299	retina vasculature morphogenesis in camera-type eye	BP	0.182	0.00584	0.0365	1.44	0.0261	Ndp/Cyp1b1	2
GO:0090037	positive regulation of protein kinase C signaling	BP	0.182	0.00584	0.0365	1.44	0.0261	Wnt11/Adra1a	2
GO:0097104	postsynaptic membrane assembly	BP	0.182	0.00584	0.0365	1.44	0.0261	Nlgn1/Cdh2	2
GO:1902513	regulation of organelle transport along microtubule	BP	0.182	0.00584	0.0365	1.44	0.0261	Map2/Fez1	2
GO:0060401	cytosolic calcium ion transport	BP	0.0348	0.00597	0.0372	1.43	0.0266	Ryr1/Adra1a/Slc24a4/Calca/Cacna1e/Grin2b/Slc8a3	7
GO:0010837	regulation of keratinocyte proliferation	BP	0.0857	0.00609	0.0376	1.42	0.0269	Cd109/Mdk/Has2	3
GO:0035116	embryonic hindlimb morphogenesis	BP	0.0857	0.00609	0.0376	1.42	0.0269	Aff3/Gpc3/Osr2	3
GO:0045987	positive regulation of smooth muscle contraction	BP	0.0857	0.00609	0.0376	1.42	0.0269	Adra1a/Npnt/Abat	3
GO:0048710	regulation of astrocyte differentiation	BP	0.0857	0.00609	0.0376	1.42	0.0269	Nog/Dab1/Serpine2	3
GO:0007517	muscle organ development	BP	0.0274	0.0061	0.0376	1.42	0.0269	Stra6/Col11a1/Lef1/Angpt1/Ryr1/Nog/Hoxd10/P2rx2/Lrp2/Hoxd9	10
GO:0051346	negative regulation of hydrolase activity	BP	0.0273	0.00621	0.0382	1.42	0.0273	Hgf/Sfrp2/Spink1/Cd109/Igf1/Gpc3/Tfpi/Nos3/Cd44/Serpine2	10
GO:0015850	organic hydroxy compound transport	BP	0.0314	0.00628	0.0386	1.41	0.0276	Apob/Stra6/Maob/Slc6a2/Syt13/Abat/Cxcl12/Cadps	8
GO:0010595	positive regulation of endothelial cell migration	BP	0.0459	0.00631	0.0387	1.41	0.0277	Angpt1/Sema5a/Igf1/Kdr/Nos3	5
GO:0006940	regulation of smooth muscle contraction	BP	0.058	0.00635	0.0389	1.41	0.0278	Adra1a/Npnt/Abat/Calca	4
GO:0031503	protein-containing complex localization	BP	0.0343	0.00646	0.0394	1.4	0.0282	Gpc6/Sgcd/Lrrc7/Drd4/Nlgn1/Tub/Nptx1	7
GO:0001837	epithelial to mesenchymal transition	BP	0.0387	0.00648	0.0394	1.4	0.0282	Sfrp2/Wnt11/Lef1/Mdk/Nog/Has2	6
GO:0007043	cell-cell junction assembly	BP	0.0387	0.00648	0.0394	1.4	0.0282	Wnt11/Ptpro/Epb41l3/Cdh6/Cdh2/Cdh10	6
GO:0048593	camera-type eye morphogenesis	BP	0.0387	0.00648	0.0394	1.4	0.0282	Ihh/Stra6/Sdk2/Tbx2/Kdr/Tenm3	6
GO:0006022	aminoglycan metabolic process	BP	0.0455	0.00655	0.0397	1.4	0.0284	Angpt1/Spock2/Ednrb/Cd44/Has2	5
GO:0002053	positive regulation of mesenchymal cell proliferation	BP	0.0833	0.00659	0.0397	1.4	0.0284	Ihh/Kdr/Foxf1	3
GO:0003203	endocardial cushion morphogenesis	BP	0.0833	0.00659	0.0397	1.4	0.0284	Nog/Tbx2/Nos3	3
GO:0008045	motor neuron axon guidance	BP	0.0833	0.00659	0.0397	1.4	0.0284	Nog/Rnf165/Cxcl12	3
GO:0048048	embryonic eye morphogenesis	BP	0.0833	0.00659	0.0397	1.4	0.0284	Ihh/Stra6/Tbx2	3
GO:0048169	regulation of long-term neuronal synaptic plasticity	BP	0.0833	0.00659	0.0397	1.4	0.0284	Grik1/Kdr/Grin2b	3
GO:0042246	tissue regeneration	BP	0.0571	0.00668	0.04	1.4	0.0286	Gap43/Mdk/Igf1/Hopx	4
GO:0048662	negative regulation of smooth muscle cell proliferation	BP	0.0571	0.00668	0.04	1.4	0.0286	Vipr2/Drd4/Nos3/Npr3	4
GO:0010634	positive regulation of epithelial cell migration	BP	0.0385	0.00668	0.04	1.4	0.0286	Angpt1/Sema5a/Igf1/Kdr/Nos3/Has2	6
GO:0021549	cerebellum development	BP	0.045	0.0068	0.0407	1.39	0.0291	Gli1/Mdk/Dab1/Cbs/Serpine2	5
GO:0048872	homeostasis of number of cells	BP	0.0269	0.00693	0.0411	1.39	0.0294	Tex15/Pla2g10/Col14a1/Crispld1/Gprasp2/Emcn/P4htm/Cdh2/Nos3/Cd44	10
GO:0007501	mesodermal cell fate specification	BP	0.167	0.00696	0.0411	1.39	0.0294	Sfrp2/Hoxa11	2
GO:0042135	neurotransmitter catabolic process	BP	0.167	0.00696	0.0411	1.39	0.0294	Maob/Abat	2
GO:0048934	peripheral nervous system neuron differentiation	BP	0.167	0.00696	0.0411	1.39	0.0294	Hoxd10/Hoxd9	2
GO:0048935	peripheral nervous system neuron development	BP	0.167	0.00696	0.0411	1.39	0.0294	Hoxd10/Hoxd9	2
GO:0099519	dense core granule cytoskeletal transport	BP	0.167	0.00696	0.0411	1.39	0.0294	Map2/Ppfia2	2
GO:0017156	calcium-ion regulated exocytosis	BP	0.0563	0.00702	0.0413	1.38	0.0296	Syn2/Rims3/Syt13/Cadps	4
GO:0050432	catecholamine secretion	BP	0.0563	0.00702	0.0413	1.38	0.0296	Syt13/Abat/Cxcl12/Cadps	4
GO:0060441	epithelial tube branching involved in lung morphogenesis	BP	0.0811	0.00712	0.0418	1.38	0.0299	Hhip/Tbx2/Foxf1	3
GO:1904707	positive regulation of vascular associated smooth muscle cell proliferation	BP	0.0811	0.00712	0.0418	1.38	0.0299	Igf1/Tert/Mmp2	3
GO:0022408	negative regulation of cell-cell adhesion	BP	0.0337	0.00715	0.0419	1.38	0.03	Ihh/Lef1/Mdk/Abat/Cd44/Serpine2/Cxcl12	7
GO:1901215	negative regulation of neuron death	BP	0.0307	0.00718	0.042	1.38	0.03	Ptprz1/Angpt1/Mdk/Igf1/Kdr/Tert/Bok/Agap2	8
GO:0030516	regulation of axon extension	BP	0.0442	0.00732	0.0428	1.37	0.0306	Map2/Sema5a/Sema5b/Sema7a/Cxcl12	5
GO:0048168	regulation of neuronal synaptic plasticity	BP	0.0556	0.00737	0.0429	1.37	0.0307	Grik1/Nog/Kdr/Grin2b	4
GO:0055008	cardiac muscle tissue morphogenesis	BP	0.0556	0.00737	0.0429	1.37	0.0307	Col11a1/Angpt1/Nog/Lrp2	4
GO:0090596	sensory organ morphogenesis	BP	0.0282	0.00755	0.0439	1.36	0.0314	Ihh/Stra6/Col11a1/Sdk2/Nog/Tbx2/Kdr/Tenm3/Osr2	9
GO:0098868	bone growth	BP	0.0789	0.00767	0.0445	1.35	0.0318	Kdr/Evc/Stc1	3
GO:0048167	regulation of synaptic plasticity	BP	0.0265	0.00771	0.0447	1.35	0.032	Grik1/Nog/Grid2ip/Rims3/Jph4/Nlgn1/Kdr/Grin2b/Serpine2/Slc8a3	10
GO:0061045	negative regulation of wound healing	BP	0.0548	0.00773	0.0447	1.35	0.032	Cd109/Abat/Tfpi/Serpine2	4
GO:0031032	actomyosin structure organization	BP	0.0329	0.0081	0.046	1.34	0.0329	Kank4/Wnt11/Frmd3/Epb41l3/Tmod2/Evl/Ccdc88a	7
GO:1902115	regulation of organelle assembly	BP	0.0329	0.0081	0.046	1.34	0.0329	Gap43/Fez1/Adamts16/Ptprd/Nptx1/Lrrc4b/Ccdc88a	7
GO:0001942	hair follicle development	BP	0.0431	0.00816	0.046	1.34	0.0329	Pla2g10/Apcdd1/Cd109/Fst/Edaradd	5
GO:0051952	regulation of amine transport	BP	0.0431	0.00816	0.046	1.34	0.0329	Grik1/Syt13/Abat/Grin2b/Cxcl12	5
GO:0003157	endocardium development	BP	0.154	0.00817	0.046	1.34	0.0329	Angpt1/Kdr	2
GO:0010838	positive regulation of keratinocyte proliferation	BP	0.154	0.00817	0.046	1.34	0.0329	Mdk/Has2	2
GO:0014052	regulation of gamma-aminobutyric acid secretion	BP	0.154	0.00817	0.046	1.34	0.0329	Grik1/Abat	2
GO:0030949	positive regulation of vascular endothelial growth factor receptor signaling pathway	BP	0.154	0.00817	0.046	1.34	0.0329	Angpt1/Kdr	2
GO:0031223	auditory behavior	BP	0.154	0.00817	0.046	1.34	0.0329	Stra6/Slc1a3	2
GO:0033240	positive regulation of cellular amine metabolic process	BP	0.154	0.00817	0.046	1.34	0.0329	Maob/Abat	2
GO:0034374	low-density lipoprotein particle remodeling	BP	0.154	0.00817	0.046	1.34	0.0329	Apob/Pla2g10	2
GO:0034392	negative regulation of smooth muscle cell apoptotic process	BP	0.154	0.00817	0.046	1.34	0.0329	Gria4/Igf1	2
GO:0035810	positive regulation of urine volume	BP	0.154	0.00817	0.046	1.34	0.0329	Ednrb/Npr3	2
GO:0048340	paraxial mesoderm morphogenesis	BP	0.154	0.00817	0.046	1.34	0.0329	Wnt11/Lef1	2
GO:0097090	presynaptic membrane organization	BP	0.154	0.00817	0.046	1.34	0.0329	Nlgn1/Ptprd	2
GO:0031281	positive regulation of cyclase activity	BP	0.0769	0.00825	0.0461	1.34	0.033	Vipr2/Calca/Nos3	3
GO:0033238	regulation of cellular amine metabolic process	BP	0.0769	0.00825	0.0461	1.34	0.033	Maob/Drd4/Abat	3
GO:0050931	pigment cell differentiation	BP	0.0769	0.00825	0.0461	1.34	0.033	Adamts20/Ednrb/Edn3	3
GO:0051180	vitamin transport	BP	0.0769	0.00825	0.0461	1.34	0.033	Stra6/Slc2a3/Lrp2	3
GO:1904645	response to amyloid-beta	BP	0.0769	0.00825	0.0461	1.34	0.033	Igf1/Itga4/Mmp2	3
GO:0052547	regulation of peptidase activity	BP	0.0248	0.00839	0.0468	1.33	0.0335	Hgf/Sfrp2/Spink1/Cd109/Igf1/Gpc3/Tfpi/Cd44/Grin2b/Serpine2/Bok	11
GO:0044070	regulation of anion transport	BP	0.0427	0.00845	0.0471	1.33	0.0337	Grik1/Pla2g10/Abat/Stc1/Grin2b	5
GO:0042982	amyloid precursor protein metabolic process	BP	0.0533	0.00849	0.0471	1.33	0.0337	Rtn1/Igf1/Itm2a/Soat1	4
GO:0045669	positive regulation of osteoblast differentiation	BP	0.0533	0.00849	0.0471	1.33	0.0337	Sfrp2/Igf1/Npnt/Nell1	4
GO:0097120	receptor localization to synapse	BP	0.0533	0.00849	0.0471	1.33	0.0337	Gpc6/Lrrc7/Nlgn1/Nptx1	4
GO:0070372	regulation of ERK1 and ERK2 cascade	BP	0.0276	0.00864	0.0479	1.32	0.0342	Angpt1/Dcc/Adra1a/Igf1/Npnt/Kdr/Cd44/Sema7a/Cxcl12	9
GO:0008585	female gonad development	BP	0.0424	0.00875	0.0483	1.32	0.0345	Angpt1/Fst/Kdr/Nos3/Mmp2	5
GO:0051897	positive regulation of protein kinase B signaling	BP	0.0424	0.00875	0.0483	1.32	0.0345	Angpt1/Sema5a/Igf1/Lrp2/Cxcl12	5
GO:0009311	oligosaccharide metabolic process	BP	0.075	0.00884	0.0487	1.31	0.0348	St6gal2/St8sia2/St8sia4	3
GO:0051349	positive regulation of lyase activity	BP	0.075	0.00884	0.0487	1.31	0.0348	Vipr2/Calca/Nos3	3
GO:0060249	anatomical structure homeostasis	BP	0.0274	0.00897	0.0493	1.31	0.0353	Tex15/Ihh/Angpt1/Col14a1/Tub/Kdr/Calca/Nos3/P2rx2	9
GO:0022405	hair cycle process	BP	0.042	0.00905	0.0495	1.31	0.0354	Pla2g10/Apcdd1/Cd109/Fst/Edaradd	5
GO:0045666	positive regulation of neuron differentiation	BP	0.042	0.00905	0.0495	1.31	0.0354	Fez1/Rgs6/Dab1/Cxcl12/Gdf7	5
GO:0043270	positive regulation of ion transport	BP	0.0274	0.00914	0.0499	1.3	0.0357	Grik1/Pla2g10/Drd4/Scn4b/Abat/Stc1/Edn3/Grin2b/Cxcl12	9
GO:0099699	integral component of synaptic membrane	CC	0.124	2.27e-11	6.89e-09	8.16	5.06e-09	Kcnj3/Efnb3/Grid1/Kcnd2/Dcc/Kcnd3/Lrrc4c/Ptpro/Nlgn1/Ptprd/Lrrc4b/Cdh2/Cacna1e/Grin2b	14
GO:0099240	intrinsic component of synaptic membrane	CC	0.114	7.24e-11	1.1e-08	7.96	8.08e-09	Kcnj3/Efnb3/Grid1/Kcnd2/Dcc/Kcnd3/Lrrc4c/Ptpro/Nlgn1/Ptprd/Lrrc4b/Cdh2/Cacna1e/Grin2b	14
GO:0097060	synaptic membrane	CC	0.0564	3.48e-10	3.09e-08	7.51	2.27e-08	Ptprz1/Kcnj3/Efnb3/Grid1/Grik1/Kcnd2/Gria4/Slc6a2/Dcc/Kcnd3/Lrrc4c/Grid2ip/Rims3/Ptpro/Nlgn1/Ptprd/Lrrc4b/Cdh2/P2rx2/Cacna1e/Grin2b/Gabra4	22
GO:0062023	collagen-containing extracellular matrix	CC	0.0556	4.64e-10	3.09e-08	7.51	2.27e-08	Ndp/Gpc6/Col11a1/Ptprz1/Hmcn1/Vit/Angpt1/Col14a1/Col4a6/Colec12/Igf1/Lamc3/Npnt/Spock2/Gpc3/Emid1/Tgfbi/Col9a2/Serpine2/Frem1/Lama4/Nid1	22
GO:0098984	neuron to neuron synapse	CC	0.0582	5.09e-10	3.09e-08	7.51	2.27e-08	Gap43/Syn2/Efnb3/Grid1/Map2/Grik1/Kcnd2/Gria4/Dcc/Kcnd3/Lrrc4c/Lrrc7/Ptpro/Ptprd/Epb41l3/Lrrc4b/Cdh2/Dab1/P2rx2/Grin2b/Slc8a3	21
GO:0099060	integral component of postsynaptic specialization membrane	CC	0.164	1.02e-09	5.18e-08	7.29	3.81e-08	Grid1/Kcnd2/Dcc/Kcnd3/Lrrc4c/Ptpro/Nlgn1/Lrrc4b/Cdh2/Grin2b	10
GO:0098948	intrinsic component of postsynaptic specialization membrane	CC	0.159	1.42e-09	6.18e-08	7.21	4.54e-08	Grid1/Kcnd2/Dcc/Kcnd3/Lrrc4c/Ptpro/Nlgn1/Lrrc4b/Cdh2/Grin2b	10
GO:0099572	postsynaptic specialization	CC	0.0568	1.99e-09	6.84e-08	7.17	5.02e-08	Gap43/Syn2/Grid1/Map2/Grik1/Kcnd2/Gria4/Dcc/Kcnd3/Lrrc4c/Lrrc7/Ptpro/Nlgn1/Epb41l3/Lrrc4b/Cdh2/Dab1/P2rx2/Grin2b/Slc8a3	20
GO:0099055	integral component of postsynaptic membrane	CC	0.129	2.02e-09	6.84e-08	7.17	5.02e-08	Grid1/Kcnd2/Dcc/Kcnd3/Lrrc4c/Ptpro/Nlgn1/Lrrc4b/Cdh2/Cacna1e/Grin2b	11
GO:0098936	intrinsic component of postsynaptic membrane	CC	0.124	3.33e-09	1.01e-07	6.99	7.44e-08	Grid1/Kcnd2/Dcc/Kcnd3/Lrrc4c/Ptpro/Nlgn1/Lrrc4b/Cdh2/Cacna1e/Grin2b	11
GO:0014069	postsynaptic density	CC	0.0576	4.1e-09	1.13e-07	6.95	8.32e-08	Gap43/Syn2/Grid1/Map2/Grik1/Kcnd2/Gria4/Dcc/Kcnd3/Lrrc4c/Lrrc7/Ptpro/Epb41l3/Lrrc4b/Cdh2/Dab1/P2rx2/Grin2b/Slc8a3	19
GO:0032279	asymmetric synapse	CC	0.056	6.35e-09	1.61e-07	6.79	1.18e-07	Gap43/Syn2/Grid1/Map2/Grik1/Kcnd2/Gria4/Dcc/Kcnd3/Lrrc4c/Lrrc7/Ptpro/Epb41l3/Lrrc4b/Cdh2/Dab1/P2rx2/Grin2b/Slc8a3	19
GO:0034702	ion channel complex	CC	0.0578	2.56e-08	5.99e-07	6.22	4.4e-07	Kcnb2/Kcnj3/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Ryr1/Scn4b/Scn1a/Ano2/Kcnq5/Cacna1e/Unc80/Grin2b/Ano1/Gabra4	17
GO:0099634	postsynaptic specialization membrane	CC	0.118	2.83e-08	6.14e-07	6.21	4.51e-07	Grid1/Kcnd2/Dcc/Kcnd3/Lrrc4c/Ptpro/Nlgn1/Lrrc4b/Cdh2/Grin2b	10
GO:0043197	dendritic spine	CC	0.0707	3.71e-08	7.53e-07	6.12	5.52e-07	Ptprz1/Slc1a3/Kcnd2/Gria4/Kcnd3/Grid2ip/Lrrc7/Drd4/Ptpro/Nlgn1/P2rx2/Ppfia2/Grin2b/Slc8a3	14
GO:0044309	neuron spine	CC	0.069	5.08e-08	9.65e-07	6.02	7.08e-07	Ptprz1/Slc1a3/Kcnd2/Gria4/Kcnd3/Grid2ip/Lrrc7/Drd4/Ptpro/Nlgn1/P2rx2/Ppfia2/Grin2b/Slc8a3	14
GO:0045211	postsynaptic membrane	CC	0.0586	5.5e-08	9.84e-07	6.01	7.22e-07	Ptprz1/Grid1/Grik1/Kcnd2/Gria4/Dcc/Kcnd3/Lrrc4c/Grid2ip/Ptpro/Nlgn1/Lrrc4b/Cdh2/Cacna1e/Grin2b/Gabra4	16
GO:0098978	glutamatergic synapse	CC	0.0526	1e-07	1.69e-06	5.77	1.24e-06	Syn2/Efnb3/Grid1/Kcnd2/Gria4/Begain/Lrrc4c/Drd4/Ptpro/Nlgn1/Ptprd/Nptx1/Lrrc4b/Ppfia2/Grin2b/Wasf3/Cadps	17
GO:0034703	cation channel complex	CC	0.0625	1.72e-07	2.75e-06	5.56	2.02e-06	Kcnb2/Kcnj3/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Ryr1/Scn4b/Scn1a/Kcnq5/Cacna1e/Unc80/Grin2b	14
GO:1902495	transmembrane transporter complex	CC	0.0457	7.28e-07	1.11e-05	4.96	8.12e-06	Kcnb2/Kcnj3/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Ryr1/Scn4b/Scn1a/Ano2/Kcnq5/Cacna1e/Unc80/Grin2b/Ano1/Gabra4	17
GO:0042734	presynaptic membrane	CC	0.0758	1.8e-06	2.49e-05	4.6	1.83e-05	Kcnj3/Efnb3/Grik1/Slc6a2/Rims3/Ptprd/Cdh2/P2rx2/Cacna1e/Grin2b	10
GO:0099061	integral component of postsynaptic density membrane	CC	0.154	3.63e-06	4.6e-05	4.34	3.37e-05	Grid1/Dcc/Lrrc4c/Ptpro/Lrrc4b/Grin2b	6
GO:0099146	intrinsic component of postsynaptic density membrane	CC	0.146	4.91e-06	5.97e-05	4.22	4.38e-05	Grid1/Dcc/Lrrc4c/Ptpro/Lrrc4b/Grin2b	6
GO:0034705	potassium channel complex	CC	0.0899	5.55e-06	6.48e-05	4.19	4.76e-05	Kcnb2/Kcnj3/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Kcnq5	8
GO:0042383	sarcolemma	CC	0.0606	1.32e-05	0.000143	3.84	0.000105	Car4/Kcnj3/Kcnd2/Ryr1/Sgcd/Adra1a/Scn1a/Cdh2/Nos3/Slc8a3	10
GO:0098839	postsynaptic density membrane	CC	0.1	4.61e-05	0.000457	3.34	0.000335	Grid1/Dcc/Lrrc4c/Ptpro/Lrrc4b/Grin2b	6
GO:0005604	basement membrane	CC	0.0672	4.66e-05	0.000457	3.34	0.000335	Hmcn1/Col4a6/Lamc3/Npnt/Tgfbi/Frem1/Lama4/Nid1	8
GO:0045121	membrane raft	CC	0.0356	0.000106	0.000948	3.02	0.000696	Angpt1/Kcnd2/Dcc/Kcnd3/Rgs16/Kdr/Ednrb/Cdh2/Tfpi/Nos3/Gnai1/Has2/Lrp2/Ano1	14
GO:0099056	integral component of presynaptic membrane	CC	0.114	0.000109	0.000948	3.02	0.000696	Kcnj3/Efnb3/Ptprd/Cdh2/Cacna1e	5
GO:0098857	membrane microdomain	CC	0.0355	0.000109	0.000948	3.02	0.000696	Angpt1/Kcnd2/Dcc/Kcnd3/Rgs16/Kdr/Ednrb/Cdh2/Tfpi/Nos3/Gnai1/Has2/Lrp2/Ano1	14
GO:0008076	voltage-gated potassium channel complex	CC	0.08	0.000162	0.00137	2.86	0.001	Kcnb2/Kcnj3/Kcnd2/Kcna6/Kcnd3/Kcnq5	6
GO:0034706	sodium channel complex	CC	0.148	0.000192	0.00157	2.8	0.00116	Grik1/Gria4/Scn4b/Scn1a	4
GO:0098889	intrinsic component of presynaptic membrane	CC	0.098	0.000221	0.00177	2.75	0.0013	Kcnj3/Efnb3/Ptprd/Cdh2/Cacna1e	5
GO:0043195	terminal bouton	CC	0.0667	0.000437	0.00341	2.47	0.0025	Grik1/Gria4/Drd4/Calca/P2rx2/Grin2b	6
GO:0005790	smooth endoplasmic reticulum	CC	0.114	0.000534	0.00406	2.39	0.00298	Map2/Ryr1/Rtn1/Jph4	4
GO:0005614	interstitial matrix	CC	0.176	0.000756	0.00547	2.26	0.00401	Vit/Col14a1/Igf1	3
GO:0043679	axon terminus	CC	0.0421	0.00112	0.0079	2.1	0.0058	Grik1/Gria4/Kcna6/Drd4/Calca/P2rx2/Grin2b/Slc8a3	8
GO:0016528	sarcoplasm	CC	0.0588	0.00229	0.0155	1.81	0.0114	Car4/Ryr1/Sgcd/Jph4/Pygm	5
GO:0031253	cell projection membrane	CC	0.0312	0.00266	0.0174	1.76	0.0128	Gap43/Ptprz1/Car4/Map2/Evc2/Evc/Epb41l3/Cd44/Lrp2/Gabra4	10
GO:0031225	anchored component of membrane	CC	0.0387	0.00362	0.022	1.66	0.0161	Gpc6/Cntn3/Car4/Cd109/Gpc3/Ntm/Sema7a	7
GO:0044853	plasma membrane raft	CC	0.0441	0.00366	0.022	1.66	0.0161	Kcnd2/Kcnd3/Cdh2/Tfpi/Nos3/Has2	6
GO:0097440	apical dendrite	CC	0.103	0.00369	0.022	1.66	0.0161	Map2/Grin2b/Osbp2	3
GO:0043292	contractile fiber	CC	0.0338	0.00439	0.0252	1.6	0.0185	Ryr1/Adra1a/Scn1a/Npnt/Tmod2/Pygm/Grin2b/Mmp2	8
GO:0030175	filopodium	CC	0.0505	0.00443	0.0252	1.6	0.0185	Gap43/Ptprz1/Map2/Lrrc7/Nlgn1	5
GO:0016342	catenin complex	CC	0.0968	0.00447	0.0252	1.6	0.0185	Cdh6/Cdh2/Cdh10	3
GO:0030426	growth cone	CC	0.0345	0.00671	0.0364	1.44	0.0267	Ptprz1/Map2/Fez1/Dcc/Itga4/Tmod2/Lrp2	7
GO:0032809	neuronal cell body membrane	CC	0.0789	0.00793	0.042	1.38	0.0309	Kcnb2/Kcnd2/Slc6a2	3
GO:0016529	sarcoplasmic reticulum	CC	0.0526	0.00927	0.0478	1.32	0.0351	Car4/Ryr1/Sgcd/Pygm	4
GO:0022836	gated channel activity	MF	0.0619	3.54e-10	1.05e-07	6.98	7.91e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Ryr1/Scn4b/Scn1a/Ano2/P2rx2/Kcnq5/Cacna1e/Grin2b/Ano1/Gabra4	20
GO:0005216	ion channel activity	MF	0.0525	4.24e-10	1.05e-07	6.98	7.91e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Ryr1/Scn4b/Slc24a4/Scn1a/Ano2/Trpm3/P2rx2/Kcnq5/Cacna1e/Unc80/Grin2b/Ano1/Gabra4	23
GO:0005261	cation channel activity	MF	0.0601	6.03e-10	1.05e-07	6.98	7.91e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Ryr1/Scn4b/Slc24a4/Scn1a/Trpm3/P2rx2/Kcnq5/Cacna1e/Unc80/Grin2b/Ano1	20
GO:0050839	cell adhesion molecule binding	MF	0.0619	9.95e-10	1.17e-07	6.93	8.87e-08	Ptprz1/Prtg/Lrrc4c/Igf1/Ptpro/Nlgn1/Ptprd/Itga4/Npnt/Kdr/Cdh6/Cdh2/Tgfbi/Nos3/Tenm3/Grin2b/Sema7a/Cxcl12/Cdh10	19
GO:0046873	metal ion transmembrane transporter activity	MF	0.0523	1.13e-09	1.17e-07	6.93	8.87e-08	Kcnk3/Kcnb2/Nalcn/Kcnj3/Slc1a3/Grik1/Slc5a11/Slc13a5/Kcnd2/Slc6a2/Kcna6/Kcnd3/Ryr1/Scn4b/Slc24a4/Scn1a/Slc12a8/Kcnq5/Cacna1e/Grin2b/Slc9a7/Slc8a3	22
GO:0015267	channel activity	MF	0.0477	2.66e-09	1.98e-07	6.7	1.5e-07	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Ryr1/Scn4b/Slc24a4/Scn1a/Ano2/Trpm3/P2rx2/Kcnq5/Cacna1e/Unc80/Grin2b/Ano1/Gabra4	23
GO:0022803	passive transmembrane transporter activity	MF	0.0477	2.66e-09	1.98e-07	6.7	1.5e-07	Kcnk3/Kcnb2/Nalcn/Kcnj3/Grid1/Grik1/Kcnd2/Gria4/Kcna6/Kcnd3/Ryr1/Scn4b/Slc24a4/Scn1a/Ano2/Trpm3/P2rx2/Kcnq5/Cacna1e/Unc80/Grin2b/Ano1/Gabra4	23
GO:0005244	voltage-gated ion channel activity	MF	0.0729	2.13e-08	1.32e-06	5.88	9.94e-07	Kcnk3/Kcnb2/Nalcn/Kcnj3/Kcnd2/Kcna6/Kcnd3/Ryr1/Scn4b/Scn1a/Kcnq5/Cacna1e/Grin2b/Ano1	14
GO:0022832	voltage-gated channel activity	MF	0.0725	2.27e-08	1.32e-06	5.88	9.94e-07	Kcnk3/Kcnb2/Nalcn/Kcnj3/Kcnd2/Kcna6/Kcnd3/Ryr1/Scn4b/Scn1a/Kcnq5/Cacna1e/Grin2b/Ano1	14
GO:0015081	sodium ion transmembrane transporter activity	MF	0.0759	4.74e-07	2.25e-05	4.65	1.7e-05	Nalcn/Slc1a3/Grik1/Slc5a11/Slc13a5/Slc6a2/Scn4b/Slc24a4/Scn1a/Slc9a7/Slc8a3	11
GO:0015079	potassium ion transmembrane transporter activity	MF	0.0701	1.05e-06	4.55e-05	4.34	3.43e-05	Kcnk3/Kcnb2/Kcnj3/Grik1/Kcnd2/Kcna6/Kcnd3/Slc24a4/Slc12a8/Kcnq5/Slc9a7	11
GO:0022843	voltage-gated cation channel activity	MF	0.0704	3.1e-06	0.000124	3.91	9.4e-05	Kcnk3/Kcnb2/Kcnj3/Kcnd2/Kcna6/Kcnd3/Ryr1/Kcnq5/Cacna1e/Grin2b	10
GO:0004970	ionotropic glutamate receptor activity	MF	0.222	3.42e-05	0.00127	2.89	0.000963	Grid1/Grik1/Gria4/Grin2b	4
GO:0001664	G protein-coupled receptor binding	MF	0.0406	4.39e-05	0.00143	2.84	0.00108	Cxcl15/Ndp/Wnt6/Wnt11/Ptch2/Gprasp2/Tub/Ednrb/Calca/Gnai1/Edn3/Grin2b/Cxcl12	13
GO:0005249	voltage-gated potassium channel activity	MF	0.0795	4.39e-05	0.00143	2.84	0.00108	Kcnk3/Kcnb2/Kcnj3/Kcnd2/Kcna6/Kcnd3/Kcnq5	7
GO:0005267	potassium channel activity	MF	0.0661	4.78e-05	0.00146	2.83	0.00111	Kcnk3/Kcnb2/Kcnj3/Grik1/Kcnd2/Kcna6/Kcnd3/Kcnq5	8
GO:0005230	extracellular ligand-gated ion channel activity	MF	0.087	9.45e-05	0.00246	2.61	0.00186	Grid1/Grik1/Gria4/P2rx2/Grin2b/Gabra4	6
GO:0045296	cadherin binding	MF	0.087	9.45e-05	0.00246	2.61	0.00186	Ptpro/Kdr/Cdh6/Cdh2/Nos3/Cdh10	6
GO:0098960	postsynaptic neurotransmitter receptor activity	MF	0.087	9.45e-05	0.00246	2.61	0.00186	Grid1/Grik1/Gria4/Drd4/Grin2b/Gabra4	6
GO:0015276	ligand-gated ion channel activity	MF	0.0593	0.000103	0.00257	2.59	0.00194	Kcnj3/Grid1/Grik1/Gria4/Ryr1/P2rx2/Grin2b/Gabra4	8
GO:0019842	vitamin binding	MF	0.0588	0.000109	0.00258	2.59	0.00195	Stra6/Abat/P3h3/Pygm/P4htm/Rbp7/Cbs/Sptlc3	8
GO:0022834	ligand-gated channel activity	MF	0.0584	0.000115	0.0026	2.59	0.00196	Kcnj3/Grid1/Grik1/Gria4/Ryr1/P2rx2/Grin2b/Gabra4	8
GO:0008509	anion transmembrane transporter activity	MF	0.0383	0.000148	0.00321	2.49	0.00243	Slc1a3/Grik1/Slc13a5/Slc6a2/Slc2a3/Slc24a4/Slc12a8/Ano2/Slc9a7/Ano1/Slc7a2/Gabra4	12
GO:0008066	glutamate receptor activity	MF	0.154	0.000156	0.00326	2.49	0.00246	Grid1/Grik1/Gria4/Grin2b	4
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	MF	0.0441	0.000173	0.00347	2.46	0.00263	Cyp3a59/Cyp1b1/Cyp3a25/Fads2/Cyp7b1/P3h3/Tet1/P4htm/Nos3/Fads1	10
GO:1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	MF	0.0962	0.000228	0.0044	2.36	0.00333	Grid1/Grik1/Gria4/Grin2b/Gabra4	5
GO:0005178	integrin binding	MF	0.0516	0.000268	0.00498	2.3	0.00376	Ptprz1/Igf1/Itga4/Npnt/Kdr/Tgfbi/Sema7a/Cxcl12	8
GO:0043177	organic acid binding	MF	0.0513	0.00028	0.00502	2.3	0.00379	Slc1a3/Grik1/Ddah1/P3h3/P4htm/Nos3/P2rx2/Grin2b	8
GO:0099529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	MF	0.0909	0.000298	0.00517	2.29	0.00391	Grid1/Grik1/Gria4/Grin2b/Gabra4	5
GO:0101020	estrogen 16-alpha-hydroxylase activity	MF	0.231	0.000316	0.0053	2.28	0.00401	Cyp3a59/Cyp1b1/Cyp3a25	3
GO:0022824	transmitter-gated ion channel activity	MF	0.0877	0.000352	0.00556	2.26	0.0042	Grid1/Grik1/Gria4/Grin2b/Gabra4	5
GO:0022835	transmitter-gated channel activity	MF	0.0877	0.000352	0.00556	2.26	0.0042	Grid1/Grik1/Gria4/Grin2b/Gabra4	5
GO:0016595	glutamate binding	MF	0.214	0.000399	0.00611	2.21	0.00461	Slc1a3/Grik1/Grin2b	3
GO:0030020	extracellular matrix structural constituent conferring tensile strength	MF	0.105	0.000699	0.0104	1.98	0.00786	Col11a1/Col14a1/Col4a6/Col9a2	4
GO:0099094	ligand-gated cation channel activity	MF	0.0583	0.000834	0.0121	1.92	0.00912	Kcnj3/Grik1/Gria4/Ryr1/P2rx2/Grin2b	6
GO:0016597	amino acid binding	MF	0.0714	0.00091	0.0128	1.89	0.00967	Slc1a3/Grik1/Ddah1/Nos3/Grin2b	5
GO:0005539	glycosaminoglycan binding	MF	0.0386	0.000933	0.0128	1.89	0.00967	Apob/Col11a1/Vit/Sema5a/Mdk/Spock2/Cd44/Nell1/Serpine2	9
GO:0004222	metalloendopeptidase activity	MF	0.0566	0.000969	0.0129	1.89	0.00978	Mmp16/Adamts20/Adamts16/Adam33/Adamts19/Mmp2	6
GO:0030594	neurotransmitter receptor activity	MF	0.0545	0.00117	0.0149	1.83	0.0113	Grid1/Grik1/Gria4/Drd4/Grin2b/Gabra4	6
GO:0005272	sodium channel activity	MF	0.0909	0.00122	0.0152	1.82	0.0115	Nalcn/Grik1/Scn4b/Scn1a	4
GO:0008373	sialyltransferase activity	MF	0.143	0.00138	0.0167	1.78	0.0126	St6gal2/St8sia2/St8sia4	3
GO:0030215	semaphorin receptor binding	MF	0.136	0.00158	0.0187	1.73	0.0142	Sema5a/Sema5b/Sema7a	3
GO:0015491	cation:cation antiporter activity	MF	0.125	0.00205	0.0237	1.62	0.0179	Slc24a4/Slc9a7/Slc8a3	3
GO:0030170	pyridoxal phosphate binding	MF	0.0769	0.00228	0.0255	1.59	0.0193	Abat/Pygm/Cbs/Sptlc3	4
GO:0005248	voltage-gated sodium channel activity	MF	0.12	0.00231	0.0255	1.59	0.0193	Nalcn/Scn4b/Scn1a	3
GO:0005506	iron ion binding	MF	0.0412	0.00238	0.0255	1.59	0.0193	Cyp3a59/Cyp1b1/Cyp3a25/Cyp7b1/P3h3/Tet1/P4htm	7
GO:0070279	vitamin B6 binding	MF	0.0755	0.00245	0.0255	1.59	0.0193	Abat/Pygm/Cbs/Sptlc3	4
GO:0015294	solute:cation symporter activity	MF	0.0526	0.00351	0.0331	1.48	0.025	Slc1a3/Slc5a11/Slc13a5/Slc6a2/Slc12a8	5
GO:0015298	solute:cation antiporter activity	MF	0.103	0.00356	0.0331	1.48	0.025	Slc24a4/Slc9a7/Slc8a3	3
GO:0017147	Wnt-protein binding	MF	0.103	0.00356	0.0331	1.48	0.025	Sfrp2/Apcdd1/Ptpro	3
GO:0045499	chemorepellent activity	MF	0.103	0.00356	0.0331	1.48	0.025	Sema5a/Sema5b/Sema7a	3
GO:0050750	low-density lipoprotein particle receptor binding	MF	0.103	0.00356	0.0331	1.48	0.025	Apob/Sacs/Lrp2	3
GO:0031406	carboxylic acid binding	MF	0.038	0.00368	0.0337	1.47	0.0255	Slc1a3/Grik1/P3h3/P4htm/Rbp7/Nos3/Grin2b	7
GO:0008237	metallopeptidase activity	MF	0.0378	0.0038	0.0341	1.47	0.0258	Cpxm2/Mmp16/Adamts20/Adamts16/Adam33/Adamts19/Mmp2	7
GO:0005251	delayed rectifier potassium channel activity	MF	0.1	0.00392	0.0346	1.46	0.0262	Kcnb2/Kcna6/Kcnq5	3
GO:0022853	active ion transmembrane transporter activity	MF	0.0336	0.00415	0.0361	1.44	0.0273	Slc1a3/Slc5a11/Slc13a5/Slc6a2/Slc24a4/Slc12a8/Slc9a7/Slc8a3	8
GO:0015293	symporter activity	MF	0.042	0.00438	0.0374	1.43	0.0283	Slc1a3/Slc5a11/Slc13a5/Slc6a2/Slc24a4/Slc12a8	6
GO:0016836	hydro-lyase activity	MF	0.0635	0.00458	0.0378	1.42	0.0286	Cyp1b1/Car4/Car8/Cbs	4
GO:0015291	secondary active transmembrane transporter activity	MF	0.0331	0.00459	0.0378	1.42	0.0286	Slc1a3/Slc5a11/Slc13a5/Slc6a2/Slc24a4/Slc12a8/Slc9a7/Slc8a3	8
GO:0005516	calmodulin binding	MF	0.0365	0.00464	0.0378	1.42	0.0286	Gap43/Map2/Ryr1/Slc24a4/Nos3/Kcnq5/Slc8a3	7
GO:0015368	calcium:cation antiporter activity	MF	0.2	0.0048	0.0379	1.42	0.0287	Slc24a4/Slc8a3	2
GO:0070643	vitamin D 25-hydroxylase activity	MF	0.2	0.0048	0.0379	1.42	0.0287	Cyp3a59/Cyp3a25	2
GO:0070325	lipoprotein particle receptor binding	MF	0.0909	0.00515	0.0396	1.4	0.03	Apob/Sacs/Lrp2	3
GO:0008083	growth factor activity	MF	0.0405	0.00517	0.0396	1.4	0.03	Hgf/Mdk/Igf1/Areg/Cxcl12/Gdf7	6
GO:0015370	solute:sodium symporter activity	MF	0.058	0.00633	0.0478	1.32	0.0361	Slc1a3/Slc5a11/Slc13a5/Slc6a2	4
GO:0005231	excitatory extracellular ligand-gated ion channel activity	MF	0.0833	0.00658	0.049	1.31	0.037	Grik1/P2rx2/Grin2b	3
GO:0015108	chloride transmembrane transporter activity	MF	0.045	0.00677	0.0497	1.3	0.0376	Slc6a2/Slc12a8/Ano2/Ano1/Gabra4	5

Visualisation

bp_dot[[3]]

mf_dot[[3]]

cc_dot[[3]]

upset[[3]]

Export Data

# save to excel
writexl::write_xlsx(x = enrichGO_sig, here::here("3_output/enrichGO_sig.xlsx"))
saveRDS(object = enrichGO_sig,file = here::here("0_data/RDS_objects/enrichGO_sig.rds"))
saveRDS(object = enrichGO,file = here::here("0_data/RDS_objects/enrichGO.rds"))

sessionInfo()

R version 4.2.1 (2022-06-23 ucrt)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19045)

Matrix products: default

locale:
[1] LC_COLLATE=English_Australia.utf8  LC_CTYPE=English_Australia.utf8   
[3] LC_MONETARY=English_Australia.utf8 LC_NUMERIC=C                      
[5] LC_TIME=English_Australia.utf8    

attached base packages:
[1] stats4    grid      stats     graphics  grDevices utils     datasets 
[8] methods   base     

other attached packages:
 [1] enrichplot_1.16.2     org.Mm.eg.db_3.15.0   AnnotationDbi_1.58.0 
 [4] IRanges_2.30.1        S4Vectors_0.34.0      Biobase_2.56.0       
 [7] BiocGenerics_0.42.0   clusterProfiler_4.4.4 Glimma_2.6.0         
[10] edgeR_3.38.4          limma_3.52.4          ggrepel_0.9.1        
[13] ggbiplot_0.55         scales_1.2.1          plyr_1.8.7           
[16] gridExtra_2.3         kableExtra_1.3.4      forcats_0.5.2        
[19] stringr_1.4.1         purrr_0.3.5           tidyr_1.2.1          
[22] ggplot2_3.3.6         tidyverse_1.3.2       reshape2_1.4.4       
[25] tibble_3.1.8          readr_2.1.3           magrittr_2.0.3       
[28] dplyr_1.0.10         

loaded via a namespace (and not attached):
  [1] utf8_1.2.2                  tidyselect_1.2.0           
  [3] RSQLite_2.2.18              htmlwidgets_1.5.4          
  [5] BiocParallel_1.30.3         scatterpie_0.1.8           
  [7] munsell_0.5.0               ragg_1.2.3                 
  [9] codetools_0.2-18            withr_2.5.0                
 [11] colorspace_2.0-3            GOSemSim_2.22.0            
 [13] highr_0.9                   knitr_1.40                 
 [15] rstudioapi_0.14             DOSE_3.22.1                
 [17] labeling_0.4.2              MatrixGenerics_1.8.1       
 [19] git2r_0.30.1                GenomeInfoDbData_1.2.8     
 [21] polyclip_1.10-0             bit64_4.0.5                
 [23] farver_2.1.1                rprojroot_2.0.3            
 [25] downloader_0.4              vctrs_0.4.2                
 [27] treeio_1.20.2               generics_0.1.3             
 [29] xfun_0.33                   R6_2.5.1                   
 [31] GenomeInfoDb_1.32.4         graphlayouts_0.8.2         
 [33] locfit_1.5-9.6              bitops_1.0-7               
 [35] cachem_1.0.6                fgsea_1.22.0               
 [37] gridGraphics_0.5-1          DelayedArray_0.22.0        
 [39] assertthat_0.2.1            promises_1.2.0.1           
 [41] ggraph_2.1.0                googlesheets4_1.0.1        
 [43] gtable_0.3.1                tidygraph_1.2.2            
 [45] workflowr_1.7.0             rlang_1.0.6                
 [47] genefilter_1.78.0           systemfonts_1.0.4          
 [49] splines_4.2.1               lazyeval_0.2.2             
 [51] gargle_1.2.1                broom_1.0.1                
 [53] yaml_2.3.5                  modelr_0.1.9               
 [55] backports_1.4.1             httpuv_1.6.6               
 [57] qvalue_2.28.0               tools_4.2.1                
 [59] ggplotify_0.1.0             ellipsis_0.3.2             
 [61] jquerylib_0.1.4             RColorBrewer_1.1-3         
 [63] Rcpp_1.0.9                  zlibbioc_1.42.0            
 [65] RCurl_1.98-1.9              viridis_0.6.2              
 [67] SummarizedExperiment_1.26.1 haven_2.5.1                
 [69] fs_1.5.2                    here_1.0.1                 
 [71] data.table_1.14.2           DO.db_2.9                  
 [73] reprex_2.0.2                googledrive_2.0.0          
 [75] whisker_0.4                 matrixStats_0.62.0         
 [77] hms_1.1.2                   patchwork_1.1.2            
 [79] evaluate_0.17               xtable_1.8-4               
 [81] XML_3.99-0.11               readxl_1.4.1               
 [83] ggupset_0.3.0               compiler_4.2.1             
 [85] writexl_1.4.0               crayon_1.5.2               
 [87] shadowtext_0.1.2            htmltools_0.5.3            
 [89] ggfun_0.0.7                 later_1.3.0                
 [91] tzdb_0.3.0                  geneplotter_1.74.0         
 [93] aplot_0.1.8                 lubridate_1.8.0            
 [95] DBI_1.1.3                   tweenr_2.0.2               
 [97] dbplyr_2.2.1                MASS_7.3-57                
 [99] Matrix_1.5-1                cli_3.4.1                  
[101] parallel_4.2.1              igraph_1.3.5               
[103] GenomicRanges_1.48.0        pkgconfig_2.0.3            
[105] xml2_1.3.3                  ggtree_3.4.4               
[107] svglite_2.1.0               annotate_1.74.0            
[109] bslib_0.4.0                 webshot_0.5.4              
[111] XVector_0.36.0              rvest_1.0.3                
[113] yulab.utils_0.0.5           digest_0.6.29              
[115] Biostrings_2.64.1           rmarkdown_2.17             
[117] cellranger_1.1.0            fastmatch_1.1-3            
[119] tidytree_0.4.1              lifecycle_1.0.3            
[121] nlme_3.1-157                jsonlite_1.8.2             
[123] viridisLite_0.4.1           fansi_1.0.3                
[125] pillar_1.8.1                lattice_0.20-45            
[127] KEGGREST_1.36.3             fastmap_1.1.0              
[129] httr_1.4.4                  survival_3.3-1             
[131] GO.db_3.15.0                glue_1.6.2                 
[133] png_0.1-7                   bit_4.0.4                  
[135] ggforce_0.4.1               stringi_1.7.8              
[137] sass_0.4.2                  blob_1.2.3                 
[139] textshaping_0.3.6           DESeq2_1.36.0              
[141] memoise_2.0.1               ape_5.6-2

GO Analysis

Ha Tran

22/08/2021

Data Setup

Import DGElist Data

GO Analysis

Visualisation

Visualisation

Visualisation

Export Data