Last updated: 2021-01-03
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Knit directory: PredictOutbredCrossVar/
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Modified: output/crossPredictions/predictedDirectionalDomCrossMeans.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVarBVs_chunk1.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVarBVs_chunk2.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVarBVs_chunk3.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVarBVs_chunk4.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVarBVs_chunk5.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVars_chunk1.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVars_chunk2.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVars_chunk3.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVars_chunk4.rds
Deleted: output/crossPredictions/predictedDirectionalDomCrossVars_chunk5.rds
Modified: output/crossPredictions/predictedUntestedCrossMeansBV.rds
Modified: output/crossPredictions/predictedUntestedCrossMeansDirDom.rds
Modified: output/crossPredictions/predictedUntestedCrossMeansTGV.rds
Modified: output/crossPredictions/predictedUntestedCrossMeans_SelIndices.rds
Modified: output/crossPredictions/predictedUntestedCrossMeans_tidy_traits.rds
Modified: output/crossPredictions/predictedUntestedCrossVars_SelIndices.rds
Modified: output/crossPredictions/predictedUntestedCrossVars_tidy_traits.rds
Modified: output/crossRealizations/realizedCrossMeans.rds
Modified: output/crossRealizations/realizedCrossMeans_BLUPs.rds
Modified: output/crossRealizations/realizedCrossMetrics.rds
Modified: output/crossRealizations/realizedCrossVars.rds
Modified: output/crossRealizations/realizedCrossVars_BLUPs.rds
Modified: output/crossRealizations/realized_cross_means_and_covs_traits.rds
Modified: output/crossRealizations/realized_cross_means_and_vars_selindices.rds
Modified: output/gblups_DirectionalDom_parentwise_crossVal_folds.rds
Modified: output/gblups_geneticgroups.rds
Modified: output/gblups_parentwise_crossVal_folds.rds
Modified: output/gebvs_ModelA_GroupAll_stdSI.rds
Modified: output/mtMarkerEffects/mt_All_A.rds
Modified: output/mtMarkerEffects/mt_All_AD.rds
Modified: output/mtMarkerEffects/mt_All_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_GG_A.rds
Modified: output/mtMarkerEffects/mt_GG_AD.rds
Modified: output/mtMarkerEffects/mt_GG_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold1_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold1_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold1_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold1_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold1_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold1_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold2_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold2_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold2_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold2_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold2_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold2_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold3_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold3_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold3_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold3_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold3_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold3_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold4_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold4_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold4_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold4_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold4_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold4_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold5_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold5_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold5_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold5_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold5_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat1_Fold5_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold1_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold1_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold1_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold1_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold1_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold1_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold2_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold2_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold2_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold2_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold2_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold2_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold3_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold3_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold3_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold3_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold3_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold3_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold4_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold4_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold4_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold4_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold4_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold4_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold5_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold5_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold5_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold5_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold5_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat2_Fold5_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold1_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold1_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold1_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold1_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold1_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold1_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold2_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold2_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold2_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold2_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold2_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold2_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold3_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold3_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold3_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold3_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold3_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold3_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold4_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold4_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold4_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold4_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold4_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold4_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold5_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold5_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold5_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold5_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold5_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat3_Fold5_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold1_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold1_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold1_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold1_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold1_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold1_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold2_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold2_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold2_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold2_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold2_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold2_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold3_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold3_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold3_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold3_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold3_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold3_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold4_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold4_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold4_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold4_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold4_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold4_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold5_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold5_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold5_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold5_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold5_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat4_Fold5_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold1_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold1_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold1_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold1_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold1_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold1_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold2_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold2_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold2_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold2_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold2_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold2_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold3_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold3_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold3_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold3_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold3_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold3_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold4_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold4_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold4_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold4_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold4_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold4_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold5_testset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold5_testset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold5_testset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold5_trainset_A.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold5_trainset_AD.rds
Modified: output/mtMarkerEffects/mt_Repeat5_Fold5_trainset_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_TMS13_A.rds
Modified: output/mtMarkerEffects/mt_TMS13_AD.rds
Modified: output/mtMarkerEffects/mt_TMS13_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_TMS14_A.rds
Modified: output/mtMarkerEffects/mt_TMS14_AD.rds
Modified: output/mtMarkerEffects/mt_TMS14_DirectionalDom.rds
Modified: output/mtMarkerEffects/mt_TMS15_A.rds
Modified: output/mtMarkerEffects/mt_TMS15_AD.rds
Modified: output/mtMarkerEffects/mt_TMS15_DirectionalDom.rds
Modified: output/obsVSpredMeans.rds
Modified: output/obsVSpredUC.rds
Modified: output/obsVSpredVars.rds
Modified: output/pmv_DirectionalDom_varcomps_geneticgroups.rds
Modified: output/pmv_varcomps_geneticgroups.rds
Modified: output/pmv_varcomps_geneticgroups_tidy_includingSIvars.rds
Modified: workflowr_log.R
Note that any generated files, e.g. HTML, png, CSS, etc., are not included in this status report because it is ok for generated content to have uncommitted changes.
These are the previous versions of the repository in which changes were made to the R Markdown (analysis/predictUntestedCrosses.Rmd
) and HTML (docs/predictUntestedCrosses.html
) files. If you’ve configured a remote Git repository (see ?wflow_git_remote
), click on the hyperlinks in the table below to view the files as they were in that past version.
File | Version | Author | Date | Message |
---|---|---|---|---|
html | 22e6c87 | wolfemd | 2021-01-03 | Build site. |
Rmd | ef3f7b3 | wolfemd | 2021-01-02 | Compile submission version of all Rmds with outstanding, uncommitted |
Rmd | c6f5e72 | wolfemd | 2020-12-02 | Add calc of SI dom. var. (previously computed on tot. variance). Tot var not computed until sup. tables now. |
Rmd | fbc72e2 | wolfemd | 2020-12-02 | Re-predicted self-crosses with corrected/updaetd predCrossVar package. |
html | 34c84f3 | wolfemd | 2020-10-27 | Build site. |
Rmd | b4edd2c | wolfemd | 2020-10-27 | Start workflowr project. |
Rmd | 7cb77ef | wolfemd | 2020-10-27 | Revised and improved the “exploration of untested crosses”. Includes a network analysis of parents and matings selected. Returns the selfs to all analyses and actually highlights them now. |
html | 3dbb1e8 | wolfemd | 2020-10-08 | Site built for first COMPLETE draft, shared with co-authors. |
html | 2e6904e | wolfemd | 2020-10-08 | Build site. |
Rmd | 17b24e6 | wolfemd | 2020-10-08 | First COMPLETE draft. Publish final changes before sharing with |
html | b06eee7 | wolfemd | 2020-08-31 | Build site. |
Rmd | 576392e | wolfemd | 2020-08-27 | Commiting all code, output and Rmd as of complete draft of results summaries + figures. Next step is to “assemble” the MS from that. |
Rmd | fb78731 | wolfemd | 2020-08-03 | Chose to switch to predType=“VPM” for this analysis to save server time. |
html | 7a4e168 | wolfemd | 2020-07-31 | Build site. |
html | a5ac99f | wolfemd | 2020-07-31 | Build site. |
html | ff4fc8b | wolfemd | 2020-07-31 | Build site. |
html | e6f8fe8 | wolfemd | 2020-07-31 | Build site. |
Rmd | 07509a8 | wolfemd | 2020-07-31 | Organized and ready to be published as a workflowr HTML page. |
Rmd | a1950f7 | wolfemd | 2020-07-29 | Directional dominance fully implemented, except in prediction of untested crosses. Presentation to NGC Leader’s call included. |
Rmd | c96001f | wolfemd | 2020-06-28 | Results and organization nearly complete. Prediction of Usefulness might be wrong (NEEDS REVIEW). |
Rmd | c0b292a | wolfemd | 2020-06-23 | Most analyses coded and complete. Moved all wrapper functions to code/*.R scripts. |
Rmd | 4846c0e | wolfemd | 2020-06-14 | All analyses completed for one-rep of parent-wise cross-val. as of June 9 Edinburgh CBDG talk. |
# devtools::install_github("wolfemd/predCrossVar", ref = 'master', force=T)
rm(list=ls()); gc()
library(tidyverse); library(magrittr); library(predCrossVar); library(BGLR);
# BLUPs -----------
<-readRDS(here::here("data","blups_forawcdata.rds")) %>%
blupsselect(Trait,blups) %>%
unnest(blups) %>%
select(Trait,germplasmName,drgBLUP) %>%
spread(Trait,drgBLUP) %>%
select(germplasmName,all_of(c("DM","logFYLD","MCMDS","TCHART"))) # precaution to ensure consistent column order
# Pedigree -----------
<-readRDS(here::here("data","ped_awc.rds")) %>%
peddistinct(sireID,damID)
<-union(ped$sireID,ped$damID)
parents
# Selection weights -----------
<-readRDS(file=here::here("data","selection_index_weights_4traits.rds"))
indices
# GEBVs --------------
<-readRDS(here::here("output","gblups_geneticgroups.rds")) %>%
gebvsfilter(Group=="All",Model=="A") %>%
unnest(GBLUPs) %>%
select(germplasmName,all_of(c("DM","logFYLD","MCMDS","TCHART")))
<-gebvs %>%
gebvMatcolumn_to_rownames(var = "germplasmName") %>%
as.matrix## GEBVs on the "standard" selection index
%<>%
gebvs mutate(stdSI=as.numeric(gebvMat%*%indices$stdSI))
saveRDS(gebvs,here::here("output","gebvs_ModelA_GroupAll_stdSI.rds"))
## The top 100 on the index
<-gebvs %>%
top100stdSIarrange(desc(stdSI)) %>%
slice(1:100) %$% germplasmName
saveRDS(top100stdSI,here::here("output","top100stdSI.rds"))
# table(top100stdSI %in% parents) # only 3
# length(grep("TMS13|TMS14|TMS15",top100stdSI, invert = T)) # 2
# length(grep("TMS13",top100stdSI)) # 52
# length(grep("TMS14",top100stdSI)) # 31
# length(grep("TMS15",top100stdSI)) # 15
## Highest BV -------------
# gebvs %>%
# slice_max(order_by = stdSI, n=1) # TMS13F1095P0013
## Lowest BV
# gebvs %>%
# filter(germplasmName %in% union(parents,top100stdSI)) %>%
# slice_min(order_by = stdSI, n=1) # IITA-TMS-IBA011371
# Crosses To Predict -------------
<-crosses2predict(union(parents,top100stdSI)) %>% # makes df of pairwise non-recprical, selfs-included crosses
CrossesToPredictbind_rows(ped %>% # add the crosses already made (for convenience)
distinct(sireID,damID)) %>%
# avoid duplication
distinct # nrow(CrossesToPredict) # [1] 47083
saveRDS(CrossesToPredict,here::here("output","CrossesToPredict_top100stdSI_and_209originalParents.rds"))
# activate multithread OpenBLAS
export OMP_NUM_THREADS=88;
library(tidyverse); library(magrittr); library(predCrossVar); library(BGLR);
# Crosses To Predict -------------
<-readRDS(here::here("output","CrossesToPredict_top100stdSI_and_209originalParents.rds"))
CrossesToPredict
# Pedigree -----------
<-readRDS(here::here("data","ped_awc.rds")) %>%
peddistinct(sireID,damID)
<-union(ped$sireID,ped$damID)
parents<-readRDS(here::here("output","top100stdSI.rds"))
top100stdSI
# Recomb frequency matrix ------------
<-readRDS(here::here("data","recombFreqMat_1minus2c_awcmap_May2020.rds"))
recombFreqMat
# Haplotype Matrix ------------
<-readRDS(file=here::here("data","haps_awc.rds"))
haploMat<-sort(c(paste0(union(parents,top100stdSI),"_HapA"),
parenthapspaste0(union(parents,top100stdSI),"_HapB")))
<-haploMat[parenthaps,colnames(recombFreqMat)]; dim(haploMat)
haploMat
# Parallelization specs ---------
require(furrr);
options(future.globals.maxSize=50000*1024^2)
<-10;
ncores
# MCMC params ------
<-30000; burnIn<-5000; thin<-5
nIter
# Path for output ----------
<-"output/crossPredictions"
outpath
# getUntestedMtCrossVarPreds function -------------
## Function to run for each rep-fold-Model (==unique set of marker effects), predict the relevant cross variances.
source(here::here("code","getUntestedMtCrossVarPreds.R"))
# Divide CrossesToPredict into chunks for each server ------------
<-5
nchunks%<>%
CrossesToPredict mutate(Chunk=rep(1:nchunks, each=ceiling(nrow(.)/nchunks), length.out=nrow(.))) %>%
nest(data=c(sireID,damID))
# cbsulm13 - done
<-1;
chunk# cbsulm15 - done
<-2;
chunk# cbsulm20 - done
<-3;
chunk# cbsulm22 - done
<-4;
chunk# cbsulm23 - done
<-5;
chunk
# Start run on each server / chunk: Aug 03 at 6:50AM
getUntestedMtCrossVarPreds(inprefix = "mt_All_AD",
outpath = "output/crossPredictions",
outprefix = paste0("predUntestedCrossTGVs_chunk",chunk,"_AD"),
predType="VPM", Model = "AD", nIter=30000, burnIn=5000,thin=5,
CrossesToPredict=CrossesToPredict$data[[chunk]],
recombFreqMat=recombFreqMat,haploMat=haploMat,ncores=ncores)
# cbsulm13 - aug 4, 10pm - done
<-1;
chunk# cbsulm15 - aug 4, 10pm - done
<-2;
chunk# cbsulm20 - aug 4, 6:55am - done
<-3;
chunk# cbsulm22 - aug 4, 10pm - done
<-4;
chunk# cbsulm23 - aug 4, 6:55am - done
<-5;
chunk
# Start run on each server / chunk:
getUntestedMtCrossVarPreds(inprefix = "mt_All_A",
outpath = "output/crossPredictions",
outprefix = paste0("predUntestedCrossBVs_chunk",chunk,"_A"),
predType="VPM", Model = "A", nIter=30000, burnIn=5000,thin=5,
CrossesToPredict=CrossesToPredict$data[[chunk]],
recombFreqMat=recombFreqMat,haploMat=haploMat,ncores=ncores)
# activate multithread OpenBLAS
export OMP_NUM_THREADS=112;
library(tidyverse); library(magrittr); library(predCrossVar); library(BGLR);
# Crosses To Predict -------------
<-readRDS(here::here("output","CrossesToPredict_top100stdSI_and_209originalParents.rds"))
CrossesToPredict
# Pedigree -----------
<-readRDS(here::here("data","ped_awc.rds")) %>%
peddistinct(sireID,damID)
<-union(ped$sireID,ped$damID)
parents<-readRDS(here::here("output","top100stdSI.rds"))
top100stdSI
# Recomb frequency matrix ------------
<-readRDS(here::here("data","recombFreqMat_1minus2c_awcmap_May2020.rds"))
recombFreqMat
# Haplotype Matrix ------------
<-readRDS(file=here::here("data","haps_awc.rds"))
haploMat<-sort(c(paste0(union(parents,top100stdSI),"_HapA"),
parenthapspaste0(union(parents,top100stdSI),"_HapB")))
<-haploMat[parenthaps,colnames(recombFreqMat)]; dim(haploMat)
haploMat
# SNP data ------------
<-readRDS(here::here("data","dosages_awc.rds")) %>%
snpsremove_invariant(.);
# Parallelization specs ---------
require(furrr);
options(future.globals.maxSize=50000*1024^2)
<-10;
ncores
# MCMC params ------
<-30000; burnIn<-5000; thin<-5
nIter
# Path for output ----------
<-"output/crossPredictions"
outpath
# getUntestedMtCrossVarPreds function -------------
## Function to run for each rep-fold-Model (==unique set of marker effects), predict the relevant cross variances.
source(here::here("code","getUntestedMtCrossVarPreds.R"))
# Divide CrossesToPredict into chunks for each server ------------
<-4
nchunks%<>%
CrossesToPredict mutate(Chunk=rep(1:nchunks, each=ceiling(nrow(.)/nchunks), length.out=nrow(.))) %>%
nest(data=c(sireID,damID))
# cbsulm13 - Done!
<-1;
chunk# cbsulm17 - Done!
<-2;
chunk# cbsulm12 - Done!
<-3;
chunk# cbsulm16 - Done!
<-4;
chunk
# Start run on each server / chunk:
getDirDomUntestedMtCrossVarTGVpreds(inprefix = "mt_All_DirectionalDom",
outpath = "output/crossPredictions",
outprefix = paste0("predUntestedCrossTGVs_chunk",chunk,"_DirDom"),
predType="VPM", nIter=30000, burnIn=5000,thin=5,
CrossesToPredict=CrossesToPredict$data[[chunk]],
recombFreqMat=recombFreqMat,haploMat=haploMat,ncores=ncores)
# cbsulm26 - Done! (~32hrs)
<-1;
chunk# cbsulm15 - Done!
<-2;
chunk# cbsulm26 - Done!
<-3;
chunk# cbsulm17 - Done!
<-4;
chunk
# Start run on each server / chunk:
getDirDomUntestedMtCrossVarBVpreds(inprefix = "mt_All_DirectionalDom",
outpath = "output/crossPredictions",
outprefix = paste0("predUntestedCrossBVs_chunk",chunk,"_DirDom"),
predType="VPM", nIter=30000, burnIn=5000,thin=5,
CrossesToPredict=CrossesToPredict$data[[chunk]],
recombFreqMat=recombFreqMat,haploMat=haploMat,doseMat=snps,ncores=ncores)
Discovered a bug effecting self-crosses. The original version of predCrossVar run (circa July 2020) incorrectly calculated gametic LD matrices with duplicated haplotypes for cases where sireID==damID. Fixed the bug in the package, archived the original version via Git/GitHub. Re-install predCrossVar on server and re-do predictions of selfs.
# activate multithread OpenBLAS
export OMP_NUM_THREADS=88;
library(tidyverse); library(magrittr); library(predCrossVar); library(BGLR);
# Crosses To Predict -------------
<-readRDS(here::here("output","CrossesToPredict_top100stdSI_and_209originalParents.rds"))
CrossesToPredict# just the selfs
%<>% filter(sireID==damID)
CrossesToPredict # Pedigree -----------
<-readRDS(here::here("data","ped_awc.rds")) %>%
peddistinct(sireID,damID)
<-union(ped$sireID,ped$damID)
parents<-readRDS(here::here("output","top100stdSI.rds"))
top100stdSI
# Recomb frequency matrix ------------
<-readRDS(here::here("data","recombFreqMat_1minus2c_awcmap_May2020.rds"))
recombFreqMat
# Haplotype Matrix ------------
<-readRDS(file=here::here("data","haps_awc.rds"))
haploMat<-sort(c(paste0(union(parents,top100stdSI),"_HapA"),
parenthapspaste0(union(parents,top100stdSI),"_HapB")))
<-haploMat[parenthaps,colnames(recombFreqMat)]; dim(haploMat)
haploMat
# Parallelization specs ---------
require(furrr);
options(future.globals.maxSize=50000*1024^2)
<-10;
ncores
# MCMC params ------
<-30000; burnIn<-5000; thin<-5
nIter
# Path for output ----------
<-"output/crossPredictions"
outpath
# getUntestedMtCrossVarPreds function -------------
## Function to run for each rep-fold-Model (==unique set of marker effects), predict the relevant cross variances.
source(here::here("code","getUntestedMtCrossVarPreds.R"))
# Start run on each server / chunk:
getUntestedMtCrossVarPreds(inprefix = "mt_All_AD",
outpath = "output/crossPredictions",
outprefix = paste0("predUntestedCrossTGVs_ReDoSelfs_AD"),
predType="VPM", Model = "AD",
nIter=30000, burnIn=5000,thin=5,
CrossesToPredict=CrossesToPredict,
recombFreqMat=recombFreqMat,
haploMat=haploMat,ncores=ncores)
# Start run on each server / chunk:
getUntestedMtCrossVarPreds(inprefix = "mt_All_A",
outpath = "output/crossPredictions",
outprefix = paste0("predUntestedCrossBVs_ReDoSelfs_A"),
predType="VPM", Model = "A",
nIter=30000, burnIn=5000,thin=5,
CrossesToPredict=CrossesToPredict,
recombFreqMat=recombFreqMat,
haploMat=haploMat,ncores=ncores)
# activate multithread OpenBLAS
export OMP_NUM_THREADS=112;
library(tidyverse); library(magrittr); library(predCrossVar); library(BGLR);
# Crosses To Predict -------------
<-readRDS(here::here("output","CrossesToPredict_top100stdSI_and_209originalParents.rds"))
CrossesToPredict
# Pedigree -----------
<-readRDS(here::here("data","ped_awc.rds")) %>%
peddistinct(sireID,damID)
<-union(ped$sireID,ped$damID)
parents<-readRDS(here::here("output","top100stdSI.rds"))
top100stdSI
# SNP data ------------
<-readRDS(here::here("data","dosages_awc.rds")) %>%
snpsremove_invariant(.);
# Parallelization specs ---------
require(furrr);
options(future.globals.maxSize=50000*1024^2)
<-10;
ncores
# MCMC params ------
<-30000; burnIn<-5000; thin<-5
nIter
# Path for output ----------
<-"output/crossPredictions"
outpath
# getMtCrossMeanPreds function -------------
source(here::here("code","getMtCrossMeanPreds.R"))
# getDirectionalDomMtCrossMeanPreds function -------------
source(here::here("code","getDirectionalDomMtCrossMeanPreds.R"))
# sampleIDs -------
<-readRDS(here::here("data","blups_forawcdata.rds")) %>%
blupsselect(Trait,blups) %>% # BLUPs long-->wide for multivar analysis
unnest(blups) %>%
select(Trait,germplasmName,drgBLUP) %>%
spread(Trait,drgBLUP) %>%
select(germplasmName,all_of(c("DM","logFYLD","MCMDS","TCHART"))) # precaution to ensure consistent column order
<-blups$germplasmName[blups$germplasmName %in% rownames(snps)]
sampleIDsrm(blups)
# Done Aug 8
<-getMtCrossMeanPreds(outprefix="mt_All_A",
predictedUntestedCrossMeansBVModel="A",
CrossesToPredict=CrossesToPredict,
doseMat=snps,
sampleIDs = sampleIDs)
<-getMtCrossMeanPreds(outprefix="mt_All_AD",
predictedUntestedCrossMeansTGVModel="AD",
CrossesToPredict=CrossesToPredict,
doseMat=snps,
sampleIDs = sampleIDs)
saveRDS(predictedUntestedCrossMeansBV,file=here::here("output/crossPredictions","predictedUntestedCrossMeansBV.rds"))
saveRDS(predictedUntestedCrossMeansTGV,file=here::here("output/crossPredictions","predictedUntestedCrossMeansTGV.rds"))
<-getDirectionalDomMtCrossMeanPreds(outprefix="mt_All_DirectionalDom",
predictedUntestedCrossMeansDirDomCrossesToPredict=CrossesToPredict,
doseMat=snps,
sampleIDs = sampleIDs)
saveRDS(predictedUntestedCrossMeansDirDom,
file=here::here("output/crossPredictions","predictedUntestedCrossMeansDirDom.rds"))
Next step, used a server, unpacking output for 10 varcomps x ~47K crosses.
Keep the dom. variance in the “tidied” output long enough to calculate dom. variance on the sel. indices. This was previously not done.
Calc. VarTGV=VarA + VarD only for the sup. tables (Tables S17 and S18), which are used for plots and summaries in the manuscript.
library(tidyverse); library(magrittr); library(predCrossVar)
# Model A
<-list.files(here::here("output/crossPredictions")) %>%
predUntestedCrossVarBVsgrep("predUntestedCrossBVs",.,value = T) %>%
tibble(File=.) %>%
mutate(Model=ifelse(grepl("_A_",File),"A","DirDomBV"),
crossPredictions=map(File,~readRDS(here::here("output/crossPredictions",.)))) %>%
unnest_wider(crossPredictions) %>%
unnest(varcovars) %>%
select(-totcomputetime) %>%
unnest_wider(varcomps) # 10 variances/covariances x 5 chunks x 1 models = 50 blocks of ~10K crosses chunk per varcomp
require(furrr); options(mc.cores=50); plan(multiprocess)
%<>% # in parallel across the 50 chunks
predUntestedCrossVarBVs mutate(predictedfamvars=future_map(predictedfamvars,~unnest(.,predVars) %>% select(-PMV))) %>%
select(-totcomputetime) %>%
unnest(predictedfamvars) %>%
rename(predVar=VPM) %>%
mutate(predOf="VarBV")
%<>% select(-VarComp,-totcomputetime) predUntestedCrossVarBVs
library(tidyverse); library(magrittr); library(predCrossVar)
# Model AD
<-list.files(here::here("output/crossPredictions")) %>%
predUntestedCrossVarTGVsgrep("predUntestedCrossTGVs",.,value = T) %>%
tibble(File=.) %>%
mutate(Model=ifelse(grepl("_AD_",File),"AD","DirDomAD"),
crossPredictions=map(File,~readRDS(here::here("output/crossPredictions",.)))) %>%
unnest_wider(crossPredictions) %>%
unnest(varcovars) %>%
select(-totcomputetime) %>%
unnest_wider(varcomps) # 10 variances/covariances x 5 chunks x 2 models = 100 blocks of ~10K crosses chunk per varcomp
$predictedfamvars[[1]] %>%
predUntestedCrossVarTGVsmutate(Nsegsnps=map_dbl(predVars,~.$Nsegsnps[1]))
require(furrr); options(mc.cores=50); plan(multiprocess)
%<>% # in parallel across the 100 chunks
predUntestedCrossVarTGVs mutate(predictedfamvars=future_map(predictedfamvars,function(predictedfamvars){
return(predictedfamvars %<>%
# format each families output in serial
mutate(Nsegsnps=map_dbl(predVars,~.$Nsegsnps[1]),
predVars=map(predVars,function(predVars){
return(predVars %>%
select(VarComp,VPM)) })) %>%
unnest(predVars))})) %>%
select(-totcomputetime) %>%
unnest(predictedfamvars) %>%
rename(predVar=VPM) %>%
rename(predOf=VarComp)
Remove the original predictions for selfs and replace with the correct predictions.
# verify nrow before removing "re-do's"
%>% dim() # [1] 947780 9
predUntestedCrossVarBVs # df of re-predicted selfs
## should only be from the ClassicAD model
<-predUntestedCrossVarBVs %>%
redoBVsfilter(grepl("_ReDoSelfs_",File))
dim(redoBVs) # [1] 6120 9
%>% count(Model,predOf)
redoBVs # Model predOf n
# <chr> <chr> <int>
# 1 A VarBV 3060
# df of original predictions (selfs and outcrosses)
# predUntestedCrossVarBVs %>%
# filter(!grepl("_ReDoSelfs_",File)) %>% # dim() # [1] 941660 9 # verify redo's removed
# filter(sireID==damID) %>% # dim() # [1] 6120 9 original self's predictions remain at this point
%<>%
predUntestedCrossVarBVs # remove all selfs from the ClassicAD model
filter(sireID!=damID | (sireID==damID & Model=="DirDomBV")) %>% # dim() # [1] 935540 9
# add back the corrected predictions for selfs
bind_rows(.,redoBVs)
<-predUntestedCrossVarTGVs %>%
redoTGVsfilter(grepl("_ReDoSelfs_",File))
dim(redoTGVs) # [1] 12240 11
%<>%
predUntestedCrossVarTGVs # remove all selfs
filter(sireID!=damID | (sireID==damID & Model=="DirDomAD")) %>% # dim() # [1] 1871080 11
# add back the corrected predictions for selfs
bind_rows(.,redoTGVs)
# dim(predUntestedCrossVarTGVs) # [1] 1883320 9
<-bind_rows(predUntestedCrossVarBVs,
predUntestedCrossVars
predUntestedCrossVarTGVs)# left_join(predUntestedCrossVarBVs %>%
# rename(predVarBV=predVarA) %>%
# select(-totcomputetime,-File),
# predUntestedCrossVarTGVs %>%
# rename(predVarTGV=predVarTot) %>%
# select(-predVarA,-predVarD,-totcomputetime,-File)) %>%
# pivot_longer(cols=c(predVarBV,predVarTGV),
# names_to = "predOf",values_to = "predVar")
# predUntestedCrossVars<-bind_rows(predUntestedCrossVarBVs,
# predUntestedCrossVarTGVs)
#predUntestedCrossVars %<>% select(Model,Trait1,Trait2,sireID,damID,predOf,predVar,Nsegsnps,totcomputetime)
saveRDS(predUntestedCrossVars,here::here("output/crossPredictions","predictedUntestedCrossVars_tidy_traits.rds"))
library(tidyverse); library(magrittr); library(predCrossVar)
<-readRDS(here::here("output/crossPredictions","predictedUntestedCrossMeansBV.rds")) %>%
predictedUntestedCrossMeansBVpluck("predictedCrossMeans")
<-readRDS(here::here("output/crossPredictions","predictedUntestedCrossMeansTGV.rds")) %>%
predictedUntestedCrossMeansTGVpluck("predictedCrossMeans")
<-readRDS(here::here("output/crossPredictions","predictedUntestedCrossMeansDirDom.rds")) %>%
predictedUntestedCrossMeansDirDompluck("predictedCrossMeans")
<-predictedUntestedCrossMeansBV %>%
predictedUntestedCrossMeansleft_join(predictedUntestedCrossMeansTGV) %>%
mutate(Model="ClassicAD") %>%
bind_rows(predictedUntestedCrossMeansDirDom %>%
mutate(Model="DirDom"))
saveRDS(predictedUntestedCrossMeans,here::here("output/crossPredictions","predictedUntestedCrossMeans_tidy_traits.rds"))
Our focus in evaluating predictions of untested crosses will be on predictions on the two SI.
times
for predicted means and variances.
library(tidyverse); library(magrittr);
# Selection weights -----------
<-readRDS(file=here::here("data","selection_index_weights_4traits.rds"))
indices
<-readRDS(here::here("output/crossPredictions","predictedUntestedCrossVars_tidy_traits.rds"))
predictedUntestedCrossVars# select(-predVarD,-totcomputetime)
## Predicted Index Variances
<-predictedUntestedCrossVars %>%
predictedUntestedCrossVars_SI# filter(Model=="A") %>%
# mutate(Model="ClassicAD") %>%
# rename(predVarBV=predVarA) %>%
# select(-predVarTot) %>%
# left_join(predictedUntestedCrossVars %>%
# filter(Model=="ClassicAD") %>%
# rename(predVarTGV=predVarTot) %>%
# select(-predVarA)) %>%
# bind_rows(predictedUntestedCrossVars %>%
# filter(Model=="DirDomAD") %>%
# rename(predVarBV=predVarA,
# predVarTGV=predVarTot)) %>%
# pivot_longer(cols=c(predVarBV,predVarTGV),names_to = "predOf",values_to = "predVar") %>%
nest(varcovars=c(Trait1,Trait2,predVar))
require(furrr); options(mc.cores=50); plan(multiprocess)
%<>%
predictedUntestedCrossVars_SI mutate(varcovars=future_map(varcovars,
function(varcovars){
# pairwise to square symmetric matrix
<-varcovars %>%
gmatspread(Trait2,predVar) %>%
column_to_rownames(var = "Trait1") %>%
%>%
as.matrix $Trait,indices$Trait]
.[indiceslower.tri(gmat)]<-t(gmat)[lower.tri(gmat)]
gmat[return(gmat) }))
%<>%
predictedUntestedCrossVars_SI mutate(stdSI=future_map_dbl(varcovars,~t(indices$stdSI)%*%.%*%indices$stdSI),
biofortSI=future_map_dbl(varcovars,~t(indices$biofortSI)%*%.%*%indices$biofortSI)) %>%
select(-varcovars)
%<>%
predictedUntestedCrossVars_SI pivot_longer(cols = c(stdSI,biofortSI),
names_to = "Trait1",
values_to = "predVar") %>%
mutate(Trait2=Trait1)
# pivot_wider(names_from = "predOf", values_from = "predVar")
# predictedUntestedCrossVars_SI %<>%
# pivot_longer(cols = c(predVarBV,predVarTGV), names_to = "predOf", values_to = "predVar")
%<>%
predictedUntestedCrossVars_SI select(Trait1,Trait2,sireID,damID,Nsegsnps,Model,predOf,predVar)
saveRDS(predictedUntestedCrossVars_SI,here::here("output/crossPredictions","predictedUntestedCrossVars_SelIndices.rds"))
# Selection weights -----------
<-readRDS(file=here::here("data","selection_index_weights_4traits.rds"))
indices<-readRDS(here::here("output/crossPredictions","predictedUntestedCrossMeans_tidy_traits.rds"))
predictedUntestedCrossMeans%<>%
predictedUntestedCrossMeans pivot_longer(cols = c(sireGEBV,damGEBV,predMeanBV,predMeanGV), names_to = "predOf", values_to = "predMean")
## Predicted Index Means
%<>%
predictedUntestedCrossMeans spread(Trait,predMean) %>%
nest(predMeans=all_of(indices$Trait)) %>%
mutate(stdSI=map_dbl(predMeans,~as.matrix(.)%*%indices$stdSI),
biofortSI=map_dbl(predMeans,~as.matrix(.)%*%indices$biofortSI)) %>%
select(-predMeans) %>%
pivot_longer(cols = c(stdSI,biofortSI), names_to = "Trait", values_to = "predMean")
%<>%
predictedUntestedCrossMeans pivot_wider(names_from = "predOf", values_from = "predMean") %>%
select(sireID,damID,Model,Trait,sireGEBV,damGEBV,predMeanBV,predMeanGV)
saveRDS(predictedUntestedCrossMeans,here::here("output/crossPredictions","predictedUntestedCrossMeans_SelIndices.rds"))
sessionInfo()
R version 4.0.2 (2020-06-22)
Platform: x86_64-apple-darwin17.0 (64-bit)
Running under: macOS Catalina 10.15.7
Matrix products: default
BLAS: /Library/Frameworks/R.framework/Versions/4.0/Resources/lib/libRblas.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/4.0/Resources/lib/libRlapack.dylib
locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8
attached base packages:
[1] stats graphics grDevices utils datasets methods base
other attached packages:
[1] workflowr_1.6.2
loaded via a namespace (and not attached):
[1] Rcpp_1.0.5 rstudioapi_0.13 whisker_0.4 knitr_1.30
[5] magrittr_2.0.1 R6_2.5.0 rlang_0.4.9 stringr_1.4.0
[9] tools_4.0.2 xfun_0.19 git2r_0.27.1 htmltools_0.5.0
[13] ellipsis_0.3.1 rprojroot_2.0.2 yaml_2.2.1 digest_0.6.27
[17] tibble_3.0.4 lifecycle_0.2.0 crayon_1.3.4 later_1.1.0.1
[21] vctrs_0.3.5 promises_1.1.1 fs_1.5.0 glue_1.4.2
[25] evaluate_0.14 rmarkdown_2.6 stringi_1.5.3 compiler_4.0.2
[29] pillar_1.4.7 httpuv_1.5.4 pkgconfig_2.0.3