Last updated: 2021-03-29

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File Version Author Date Message
Rmd 3720d88 sam-widmayer 2021-03-29 integrate toxin24A
Rmd 736d501 sam-widmayer 2021-03-29 integrate toxin24A
Rmd ecf1af1 sam-widmayer 2021-03-29 integrate toxin24A
html 0e83f2b sam-widmayer 2021-03-24 Build site.
Rmd 7d105e2 sam-widmayer 2021-03-24 progress meeting updates
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Rmd f2b09cd sam-widmayer 2021-03-23 EC plot and DRC evaluation updates
Rmd 07d524b sam-widmayer 2021-03-23 EC plot and DRC evaluation updates
html deb1df5 sam-widmayer 2021-03-21 Build site.
Rmd 32ad79a sam-widmayer 2021-03-21 heatmap outputs
Rmd 7ccc7de sam-widmayer 2021-03-21 heatmap outputs
Rmd 01b3361 sam-widmayer 2021-03-21 heatmap outputs
Rmd 7eb07f1 sam-widmayer 2021-03-21 toxin23 updates and Worm_Length filter for MDHD data
html 7ae886c sam-widmayer 2021-03-14 Build site.
Rmd 3f4a99b sam-widmayer 2021-03-14 integrate toxin22 results
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Rmd 46c9647 sam-widmayer 2021-03-06 static working directory
Rmd 41bdaa0 sam-widmayer 2021-03-05 dynamic working directory
Rmd 0c9d312 sam-widmayer 2021-03-05 initiate toxin DRC analysis repo

Purpose:

  • Compile past assay results.
  • Provide dose-response curves for each toxin.

Analysis Date: March 29, 2021

Assay Summary

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   Metadata_Experiment bleach    median cv.censor
1             toxin09A      1 0.3836145         0
2             toxin10A      1 0.4305145         0
3             toxin11A      1 0.4277093         0
4             toxin14A      1 0.3309190         0
5             toxin14A      2 0.6202207         1
6             toxin14A      3 0.3139512         0
7             toxin14B      1 0.3531075         0
8             toxin14B      2 0.6821373         1
9             toxin14B      3 0.4144394         0
10            toxin15A      1 0.3776043         0
11            toxin15A      2 0.3237794         0
12            toxin15A      3 0.5858180         1
13            toxin15B      1 0.3014705         0
14            toxin15B      2 0.3782805         0
15            toxin15B      3 0.5791055         1
16            toxin16A      1 0.3024091         0
17            toxin16A      2 0.6394078         1
18            toxin16A      3 0.6430524         1
19            toxin17A      1 0.3203867         0
20            toxin17A      2 0.5750981         1
21            toxin17A      3 0.3401813         0
22            toxin18A      1 0.3202607         0
23            toxin18A      2 0.3228881         0
24            toxin18A      3 0.3338709         0
25            toxin19A      1 0.3333869         0
26            toxin19A      2 0.3179010         0
27            toxin19A      3 0.3330344         0
28            toxin22A      1 0.2625332         0
29            toxin22A      2 0.2967801         0
30            toxin22A      3 0.2706957         0
31            toxin23A      1 0.3243216         0
32            toxin23A      2 0.3411546         0
33            toxin23A      3 0.2809086         0
34            toxin24A      1 0.2672445         0
35            toxin24A      2 0.3018825         0
36            toxin24A      3 0.3152494         0
                         Df Sum Sq Mean Sq F value   Pr(>F)    
assay                    13 2.0982  0.1614  17.352  < 2e-16 ***
as.factor(bleach)         2 0.6464  0.3232  34.747 5.67e-14 ***
strain                    7 0.0988  0.0141   1.517    0.162    
assay:as.factor(bleach)  20 1.8536  0.0927   9.964  < 2e-16 ***
Residuals               239 2.2230  0.0093                     
---
Signif. codes:  0 '***' 0.001 '**' 0.01 '*' 0.05 '.' 0.1 ' ' 1

Silver

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deb1df5 sam-widmayer 2021-03-21
cb6e132 sam-widmayer 2021-03-06

Cadmium

[1] "Excluding toxin09A: Inconsistent Response"

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Copper

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Nickel

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Paraquat

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Zinc

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Pyraclostrobin

[1] "Excluding toxin11A: Inconsistent Response"

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Aldicarb

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Chlorfenapyr

[1] "Excluding toxin09A, toxin10A, toxin11A, toxin12A: No Response/Variable Dilution"

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Methomyl

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Methyl Mercury

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Triphenyl phosphate

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Arsenic trioxide

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Carbaryl

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Carboxin

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Chlorpyrifos

[1] "Excluding toxin17A: No Response"

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Lead (II) nitrate

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Atrazine

[1] "Excluding toxin16A: Inaccurate Dilution Series"

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2,4-D

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Malathion

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Chlorothalonil

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Deltamethrin

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Error in optim(startVec, opfct, hessian = TRUE, method = optMethod, control = list(maxit = maxIt,  : 
  non-finite finite-difference value [3]
[1] "Unable to optimize model"
[1] "Unable to optimize model"

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Manganese dichloride

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Propoxur

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EC Estimates

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EC10

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EC50

EC90

Summary Tables



Table: Aldicarb Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
ECA396   106.6±5.32     119.63±5.21    120.01±4.98  
CB4856   131.29±14.22   145.55±14.92   141.15±12.92 
ECA36    127.11±7.94    146.47±8.27    145.24±7.7   
MY16     75.21±5.64     81.46±5.03     81.67±4.79   
XZ1516   136.11±8.78    152.11±9.42    151.85±9.14  
RC301    85.86±5.27     95.23±4.71     95.06±4.47   
PD1074   102.12±6.08    111.82±4.69    112.16±4.47  
ECA248   83.75±10.62    97.32±11.12    99.38±10.83  


Table: Aldicarb Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
ECA396   338.59±16.38   342.43±17.04   353.82±18.78 
CB4856   289.68±13.5    280.72±14.9    275.59±14.66 
ECA36    334.68±13.31   318.92±11.19   320.12±11.38 
MY16     230.52±13.76   237.66±16.61   244.01±17.83 
XZ1516   359.56±15.28   353.64±15.46   351.99±15.53 
RC301    272.07±12.99   282.15±13.56   288.18±15.05 
PD1074   268.87±8.57    268.2±7.65     267.59±7.68  
ECA248   292.92±22.78   286.85±24.77   281.92±23.83 


Table: Aldicarb Estimates

Strain   Weibull        Log-Logistic    Lognormal      
-------  -------------  --------------  ---------------
ECA396   707.19±56.27   980.14±103.2    1043.12±113.33 
CB4856   479.65±35.86   541.42±48.19    538.07±46.76   
ECA36    620.27±42.68   694.39±55.48    705.57±52.72   
MY16     470.65±47.59   693.4±97.41     729.07±106.04  
XZ1516   667.76±45.95   822.16±81.96    815.91±77.84   
RC301    567.42±50.45   835.93±88.46    873.63±97.8    
PD1074   498.29±34.45   643.29±41.42    638.44±40.11   
ECA248   650.54±83.67   845.45±159.77   799.73±142.45  


Table: Arsenic trioxide Estimates

Strain   Weibull         Log-Logistic   Lognormal     
-------  --------------  -------------  --------------
PD1074   424.78±310.18   852.9±932.35   639.16±201.42 


Table: Atrazine Estimates

Strain   Weibull         Log-Logistic     Lognormal     
-------  --------------  ---------------  --------------
ECA248   231.03±45.22    305.76±96.3      610.18±710.96 
PD1074   323.78±159.61   430.95±237.65    NA            
XZ1516   259.56±83.83    338.98±134.82    604.71±670.12 
RC301    180.06±17.9     221.04±30.53     279.45±92.4   
CB4856   302.15±214.96   452.74±379.63    NA            
ECA36    551.13±889.49   832.27±1429.92   NA            
ECA396   259.49±90.99    400.28±199.19    NA            


Table: Atrazine Estimates

Strain   Weibull         Log-Logistic    Lognormal 
-------  --------------  --------------  ----------
ECA248   740.46±247.7    NA              NA        
XZ1516   914.35±412.62   NA              NA        
RC301    603.8±106.15    824.22±223.15   NA        


Table: Cadmium dichloride Estimates

Strain   Weibull      Log-Logistic   Lognormal  
-------  -----------  -------------  -----------
MY16     28.14±1.64   31.13±1.67     31.59±1.72 
XZ1516   26.6±1.6     29.42±1.58     30.05±1.6  
PD1074   23.53±1.31   26.57±1.35     27.06±1.33 
ECA36    26.9±1.84    29.62±1.73     30.16±1.7  
ECA396   29.31±1.55   32.27±1.51     32.85±1.53 
RC301    23.34±1.43   26.19±1.52     26.79±1.54 
ECA248   22.65±1.73   26.23±1.88     26.63±1.75 
CB4856   20.86±1.29   23.39±1.27     23.74±1.23 


Table: Cadmium dichloride Estimates

Strain   Weibull      Log-Logistic   Lognormal  
-------  -----------  -------------  -----------
MY16     64.99±2.21   63.75±2.62     63.21±2.44 
XZ1516   68.01±2.06   69.01±3.08     67.94±3.02 
PD1074   61.28±1.93   60.8±2.43      60.08±2.3  
ECA36    71.73±2.59   74.71±4.46     73.75±4.71 
ECA396   66.46±1.97   64.6±2.33      64.11±2.13 
RC301    62.37±2.07   63.72±2.98     62.59±2.91 
ECA248   55.81±3.09   54.95±2.94     54.87±2.85 
CB4856   63.35±2.51   67.13±4.23     66.89±4.73 


Table: Cadmium dichloride Estimates

Strain   Weibull       Log-Logistic   Lognormal    
-------  ------------  -------------  -------------
MY16     110.8±5.68    130.56±12.6    126.51±11.24 
XZ1516   123.7±6.08    161.83±17.21   153.63±16.17 
PD1074   112.75±5.64   139.09±13.24   133.39±11.7  
ECA36    134±8.18      188.45±25.35   180.32±25.7  
ECA396   111.97±4.91   129.34±10.75   125.14±9.36  
RC301    116.68±6.33   155.04±17.73   146.24±16.32 
ECA248   99.15±9.98    115.09±15.76   113.06±13.81 
CB4856   128.58±8.32   192.63±26.29   188.48±28.18 


Table: Carbaryl Estimates

Strain   Weibull        Log-Logistic   Lognormal     
-------  -------------  -------------  --------------
RC301    153.86±13.45   206.66±31.25   318.49±148.7  
MY16     115.77±4.5     131.85±4.29    135.52±4.16   
XZ1516   138.51±5.63    160.03±6.16    167.91±8.08   
ECA248   215.06±13.53   263.15±26.42   350.16±107.75 
CB4856   200.77±7.47    224.45±7.79    232.64±9.74   
ECA396   118.25±6.19    134.47±5.88    138.17±5.63   
ECA36    282.12±38.73   391.53±85.12   NA            


Table: Carbaryl Estimates

Strain   Weibull         Log-Logistic    Lognormal    
-------  --------------  --------------  -------------
RC301    560.72±88.19    899.1±242.48    NA           
MY16     329.43±10.08    372.72±19.75    377.73±25.18 
XZ1516   396.9±19.22     480.15±41.68    527.38±71.69 
ECA248   599.91±67.03    828.28±158.41   NA           
CB4856   477.83±21.16    543.72±40.07    589.88±68.61 
ECA396   334.69±14.2     365.03±24.39    365.57±28.19 
ECA36    823.29±165.63   NA              NA           


Table: Carbaryl Estimates

Strain   Weibull        Log-Logistic   Lognormal  
-------  -------------  -------------  -----------
MY16     641.47±34.4    NA             NA         
XZ1516   776.32±60.67   NA             NA         
CB4856   830.35±58.18   NA             NA         
ECA396   649.51±47.04   990.92±136.9   967.21±149 


Table: Carboxin Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
RC301    245.37±13.69   268.12±13.33   271.54±13.17 
MY16     208.99±11.87   232.92±11.41   236.38±11.06 
XZ1516   246.6±16.77    281.8±17.27    286.26±17.03 
PD1074   294.44±24.48   321.2±23.59    326.03±23.43 
ECA248   264.83±20      294.25±19.9    298.93±19.58 
CB4856   218.08±16.13   242.89±15.96   246.14±15.48 
ECA396   270.53±11.22   295.77±10.69   298.53±10.38 
ECA36    343.43±23.11   376.82±22.71   382.09±22.25 


Table: Carboxin Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
RC301    518.27±12.99   520.48±15.19   514.66±14.85 
MY16     542.31±16.17   559.04±22.25   551.86±22.67 
XZ1516   634.1±24.55    652.59±34.08   647.19±35.34 
PD1074   762.58±35.12   837.75±72.34   829.67±86.63 
ECA248   653.85±27.45   672.27±39.66   662.19±40.07 
CB4856   567.38±22.5    585.55±31.62   575.34±31.85 
ECA396   543.23±11.13   538.19±12.02   534.45±11.71 
ECA36    721.61±27.71   712.59±33.79   705.55±31.94 


Table: Carboxin Estimates

Strain   Weibull          Log-Logistic     Lognormal      
-------  ---------------  ---------------  ---------------
RC301    834.65±39.4      1010.37±74.89    975.44±68.53   
MY16     995.79±54.82     1341.73±127.72   1288.38±122.31 
XZ1516   1157.57±81.68    1511.25±193.26   1463.19±189.76 
PD1074   1398.49±106.11   NA               NA             
ECA248   1163.1±82.92     1535.93±209.95   1466.89±201.43 
CB4856   1043.54±72.96    1411.64±179.5    1344.81±169.67 
ECA396   847.09±31.39     979.33±52.28     956.83±47.61   
ECA36    1158.26±71.01    1347.56±144.72   1302.84±129.29 


Table: Chlorfenapyr Estimates

Strain   Weibull     Log-Logistic   Lognormal 
-------  ----------  -------------  ----------
ECA248   0.19±0.01   0.2±0.01       0.2±0.01  
XZ1516   0.31±0.01   0.35±0.02      0.35±0.02 
ECA36    0.94±0.03   1.03±0.03      1.04±0.02 
CB4856   0.29±0.01   0.29±0.01      0.29±0.01 
PD1074   0.35±0.01   0.35±0.01      0.34±0.01 
RC301    0.22±0.01   0.23±0.01      0.24±0.01 
MY16     0.21±0.01   0.22±0.01      0.23±0.01 
ECA396   NA          0.54±0.01      0.54±0.01 


Table: Chlorfenapyr Estimates

Strain   Weibull     Log-Logistic   Lognormal 
-------  ----------  -------------  ----------
ECA248   0.49±0.02   0.49±0.02      0.49±0.02 
XZ1516   0.67±0.01   0.67±0.01      0.67±0.01 
ECA36    1.65±0.04   1.53±0.05      1.54±0.04 
CB4856   0.56±0.01   0.56±0.01      0.55±0.01 
PD1074   0.6±0.01    0.61±0.01      0.61±0.01 
RC301    0.49±0.01   0.48±0.01      0.48±0.01 
MY16     0.51±0.01   0.5±0.01       0.5±0.01  
ECA396   NA          0.75±0.02      0.76±0.02 


Table: Chlorfenapyr Estimates

Strain   Weibull     Log-Logistic   Lognormal 
-------  ----------  -------------  ----------
ECA248   0.92±0.06   1.22±0.11      1.18±0.11 
XZ1516   1.1±0.05    1.27±0.08      1.27±0.07 
ECA36    2.35±0.1    2.27±0.17      2.26±0.15 
CB4856   0.85±0.02   1.06±0.05      1.05±0.04 
PD1074   0.84±0.02   1.07±0.04      1.1±0.04  
RC301    0.81±0.02   1±0.05         0.96±0.04 
MY16     0.89±0.03   1.13±0.06      1.1±0.06  
ECA396   NA          1.04±0.06      1.06±0.05 


Table: Chlorothalonil Estimates

Strain   Weibull       Log-Logistic   Lognormal   
-------  ------------  -------------  ------------
CB4856   56.12±15.88   57.18±11.76    58.03±11.27 
ECA36    5.77±2.69     10.92±10.63    26.4±69.2   
ECA396   36.35±5.25    44.47±8.22     52.94±23.97 
XZ1516   43.81±8.96    48.18±7.94     49.29±8.24  


Table: Chlorothalonil Estimates

Strain   Weibull        Log-Logistic    Lognormal     
-------  -------------  --------------  --------------
CB4856   120.03±12.84   143.37±47.58    154.83±101.63 
ECA36    81.35±75.96    240.94±452.37   NA            
ECA396   121.84±23.79   174.49±69.55    NA            
XZ1516   112.35±14.12   134.26±39.1     144.69±70.86  


Table: Chlorothalonil Estimates

Strain   Weibull        Log-Logistic   Lognormal 
-------  -------------  -------------  ----------
CB4856   194.87±42.46   NA             NA        
XZ1516   204.75±47.75   NA             NA        


Table: Chlorpyrifos Estimates

Strain   Weibull       Log-Logistic   Lognormal   
-------  ------------  -------------  ------------
MY16     15.55±39.17   NA             NA          
XZ1516   2.72±0.14     3.2±0.18       3.53±0.37   
PD1074   2.71±4.57     8.49±13.73     NA          
ECA248   2.06±0.98     3.57±2.32      12.24±14.97 
CB4856   3.88±3.06     10.87±10.59    NA          
ECA396   3.79±6.17     10.36±20.26    NA          
ECA36    1.81±0.11     2.27±0.18      2.67±0.41   


Table: Chlorpyrifos Estimates

Strain   Weibull       Log-Logistic   Lognormal  
-------  ------------  -------------  -----------
XZ1516   8.19±0.61     10.39±1.32     13.29±3.38 
ECA248   17.87±12.12   NA             NA         
ECA36    7.39±0.76     10.32±1.69     14.8±4.74  


Table: Chlorpyrifos Estimates

Strain   Weibull      Log-Logistic   Lognormal 
-------  -----------  -------------  ----------
XZ1516   16.56±1.87   NA             NA        
ECA36    18.1±2.6     NA             NA        


Table: Copper(II) chloride Estimates

Strain   Weibull        Log-Logistic   Lognormal  
-------  -------------  -------------  -----------
PD1074   173.47±169.3   51.04±2.93     54.15±5.88 
ECA396   NA             52.9±3.01      53.22±2.88 
MY16     NA             50.75±2.98     59.68±4.3  


Table: Copper(II) chloride Estimates

Strain   Weibull   Log-Logistic   Lognormal    
-------  --------  -------------  -------------
ECA396   NA        112.25±9.11    118.79±15.9  
MY16     NA        108.46±8.44    96.73±4.04   
PD1074   NA        111.77±9.35    163.21±42.85 


Table: Copper(II) chloride Estimates

Strain   Weibull   Log-Logistic   Lognormal    
-------  --------  -------------  -------------
MY16     NA        NA             156.76±16.54 


Table: Deltamethrin Estimates

Strain   Weibull     Log-Logistic   Lognormal   
-------  ----------  -------------  ------------
PD1074   0.04±0.23   0.33±2.41      0.43±2.35   
CB4856   0.15±0.58   16.9±76.2      21.17±77.68 
ECA36    0±0         0±0            0±0         
MY16     0.21±0.46   0.49±2.62      0.91±4.32   
ECA396   0.18±0.67   26.52±85.9     1.36±3.48   
RC301    0.54±4.71   0.98±4.87      2.43±14.96  
XZ1516   0±0         NA             0±0         


Table: Deltamethrin Estimates

Strain   Weibull          Log-Logistic     Lognormal     
-------  ---------------  ---------------  --------------
ECA36    319.82±7642.14   38.64±432.2      22.07±288.54  
XZ1516   0±0              NA               24.67±2748.05 
PD1074   NA               306.46±2784.41   466.6±6933.93 
CB4856   NA               163.38±158.03    156.8±160.65  
ECA396   NA               181.73±145.01    NA            


Table: Deltamethrin Estimates

Strain   Weibull   Log-Logistic      Lognormal      
-------  --------  ----------------  ---------------
CB4856   NA        1579±4811.27      1161.27±2335.7 
ECA396   NA        1245.31±2455.33   NA             


Table: Lead(II) nitrate Estimates

Strain   Weibull         Log-Logistic   Lognormal 
-------  --------------  -------------  ----------
ECA36    233.52±141.68   556.99±619.9   NA        


Table: Malathion Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
PD1074   43.1±8.32      55.03±8.58     57.77±8.27   
CB4856   63.14±15.09    81.48±14.72    82.1±13.75   
ECA36    154.44±41.48   173.94±39.44   175.59±37.24 
MY16     57.84±16.26    73.8±16.64     75.96±15.69  
ECA396   58.18±12.11    72.53±11.98    75.55±11.52  
RC301    24.24±6.59     33.82±7.15     36.21±7.04   
XZ1516   53.69±12.95    73.68±13.64    77.04±13.05  
ECA248   65.46±21.75    71.99±24.52    73.54±25.32  


Table: Malathion Estimates

Strain   Weibull        Log-Logistic    Lognormal     
-------  -------------  --------------  --------------
PD1074   237.01±17.55   239.09±20.55    232.69±19.32  
CB4856   236.07±22.03   228.05±20.67    226.28±20.44  
ECA36    578.45±86.47   589.44±116.12   582.05±117.28 
MY16     227.41±29.29   213.51±28.3     212.64±27.16  
ECA396   242.49±22.58   233.04±23.45    231.16±22.3   
RC301    139.79±11.92   139.37±12.11    136.55±11.53  
XZ1516   367.59±50.61   376.79±63.33    376.73±64.69  
ECA248   182.41±22.05   179.76±23.21    176.34±22.91  


Table: Malathion Estimates

Strain   Weibull          Log-Logistic     Lognormal      
-------  ---------------  ---------------  ---------------
PD1074   702.33±101.76    1038.8±234.25    937.23±189.82  
CB4856   547.07±103.75    638.28±137.36    623.64±120.97  
ECA36    1341.97±345.75   1997.5±866.47    1929.38±827.65 
MY16     544.19±119.51    617.68±189.19    595.26±160.82  
ECA396   602.25±103.68    748.74±183.23    707.28±155.82  
RC301    426.97±69.66     574.25±137.49    514.92±107.57  
XZ1516   1252.49±351.79   1926.96±795.09   1842.32±737.53 
ECA248   350.51±65.05     448.83±158.07    422.87±142.46  


Table: Manganese dichloride Estimates

Strain   Weibull           Log-Logistic     Lognormal     
-------  ----------------  ---------------  --------------
PD1074   493.38±73.5       586.18±125.39    639.75±257.73 
MY16     1820.28±1973.15   NA               NA            
RC301    1141.28±129.55    1212.69±191.27   NA            


Table: Manganese dichloride Estimates

Strain   Weibull          Log-Logistic      Lognormal       
-------  ---------------  ----------------  ----------------
PD1074   1220.87±307.8    1655.46±1033.91   1906.81±2140.97 
RC301    1575.29±155.27   1871.07±792.42    NA              


Table: Manganese dichloride Estimates

Strain   Weibull         Log-Logistic   Lognormal 
-------  --------------  -------------  ----------
RC301    1934.45±391.2   NA             NA        


Table: Methomyl Estimates

Strain   Weibull      Log-Logistic   Lognormal  
-------  -----------  -------------  -----------
ECA396   9.84±0.65    11.14±0.66     11.23±0.66 
CB4856   9.52±0.76    10.68±0.77     10.81±0.76 
ECA36    7.37±0.55    8.63±0.56      8.8±0.56   
MY16     9±0.75       10.18±0.8      10.26±0.8  
XZ1516   5.68±0.47    6.64±0.48      6.71±0.47  
RC301    9.3±0.77     10.53±0.73     10.53±0.71 
PD1074   6.36±0.6     7.36±0.6       7.51±0.6   
ECA248   11.36±0.79   12.7±0.78      12.77±0.79 


Table: Methomyl Estimates

Strain   Weibull      Log-Logistic   Lognormal  
-------  -----------  -------------  -----------
ECA396   34.87±1.84   39.44±3.32     40.8±4.46  
CB4856   32.53±1.51   33.54±2.07     32.91±2.09 
ECA36    30.44±1.18   31.58±1.56     30.96±1.57 
MY16     28.98±1.33   28.96±1.66     28.3±1.61  
XZ1516   27.78±1.53   29.89±2.22     29.78±2.42 
RC301    33.24±1.81   36.71±2.83     37.62±3.53 
PD1074   26.35±1.83   29.04±2.83     29.15±3.24 
ECA248   39.06±1.59   40.21±2.03     39.87±2.12 


Table: Methomyl Estimates

Strain   Weibull      Log-Logistic   Lognormal    
-------  -----------  -------------  -------------
ECA396   78.11±6.67   139.62±23.51   148.17±31.72 
CB4856   71.16±5.49   105.36±14.51   100.13±13.94 
ECA36    75.12±5.42   115.61±13.69   108.87±12.94 
MY16     61.04±4.27   82.42±10.52    78.1±9.63    
XZ1516   76.39±7.1    134.48±21.6    132.25±22.74 
RC301    74.82±7.51   127.94±21.66   134.35±26.78 
PD1074   65.17±7.62   114.61±23.69   113.17±26.23 
ECA248   85.82±6.18   127.32±14.83   124.45±15.16 


Table: Methylmercury dichloride Estimates

Strain   Weibull     Log-Logistic   Lognormal 
-------  ----------  -------------  ----------
ECA396   1.68±0.17   2.08±0.19      2.15±0.19 
CB4856   0.93±0.13   1.25±0.16      1.34±0.16 
ECA36    1.41±0.19   1.85±0.25      2.04±0.3  
MY16     1.35±0.22   1.71±0.26      1.79±0.28 
XZ1516   1.59±0.22   2.04±0.26      2.17±0.29 
RC301    2.01±0.23   2.54±0.26      2.66±0.27 
PD1074   1.15±0.15   1.59±0.21      1.77±0.28 
ECA248   0.78±0.42   1.91±1.83      3.88±4.81 


Table: Methylmercury dichloride Estimates

Strain   Weibull       Log-Logistic   Lognormal   
-------  ------------  -------------  ------------
ECA396   11.65±1.3     14.35±2.12     15.13±2.72  
CB4856   11.9±1.89     14.09±3.1      14.84±3.83  
ECA36    19.08±3.26    25.82±6.68     31.3±11.16  
MY16     11.5±2.38     15.28±3.98     17.05±5.72  
XZ1516   15.25±2.32    20.5±4.73      23.8±7.73   
RC301    14.91±1.63    19.43±3.46     20.55±4.91  
PD1074   14.17±2.31    21.2±5.81      25.96±10.78 
ECA248   29.46±26.51   123.34±195.2   NA          


Table: Methylmercury dichloride Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
ECA396   39.95±6.95     98.84±27.57    106.29±35.25 
CB4856   60.34±14.94    158.89±67.62   164.41±80.5  
ECA36    100.49±24.44   NA             NA           
MY16     44.99±14.04    136.51±64.26   162.42±96.96 
XZ1516   64.39±14.94    206±86.51      NA           
RC301    53.39±9.23     148.76±50.78   158.69±71    
PD1074   70.13±17.42    NA             NA           


Table: Nickel dichloride Estimates

Strain   Weibull      Log-Logistic   Lognormal  
-------  -----------  -------------  -----------
ECA396   49.7±2.61    50.33±2.22     50.28±1.96 
CB4856   50.68±2.88   51.22±2.44     51.25±2.14 
ECA36    55.05±3      59.22±1.98     60.9±2.14  
MY16     44.68±2.65   47.86±2.13     48.35±1.95 
PD1074   63.57±3.9    65.07±3.39     63.88±2.57 


Table: Nickel dichloride Estimates

Strain   Weibull       Log-Logistic   Lognormal    
-------  ------------  -------------  -------------
ECA396   86.77±1.57    85.7±1.93      84.36±1.9    
CB4856   88.1±1.64     87.41±2.05     86.07±2.05   
ECA36    109.91±3.92   125.24±10.24   137.56±20.11 
MY16     97.46±2.88    108.47±6.75    112.38±10.43 
PD1074   106.19±1.94   111.39±4.78    115.71±7.37  


Table: Nickel dichloride Estimates

Strain   Weibull        Log-Logistic   Lognormal   
-------  -------------  -------------  ------------
ECA396   123.76±3.33    145.93±7.24    141.52±6.56 
CB4856   125.33±3.7     149.18±8.14    144.55±7.32 
ECA36    170.78±14.03   NA             NA          
MY16     160.2±10.06    NA             NA          
PD1074   147.27±8.23    190.66±24.01   NA          


Table: Paraquat Estimates

Strain   Weibull      Log-Logistic   Lognormal  
-------  -----------  -------------  -----------
MY16     42.55±3.71   40.32±2.97     39.4±2.61  
XZ1516   48.85±4.7    57.25±4.48     58.59±4.23 
CB4856   40.38±3.35   40.62±2.9      39.46±2.7  
RC301    15.69±1.75   22.62±1.85     22.84±1.66 
PD1074   29.52±2.8    30.58±2.27     29.76±2.09 
ECA248   29.11±3.68   28.73±2.32     28.45±2.28 
ECA36    56.24±4.19   46.32±3.49     45.9±3.55  
ECA396   15±1.59      21.65±1.64     21.82±1.5  


Table: Paraquat Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
MY16     128.8±6.47     150.04±10.7    165.36±12.34 
XZ1516   314.23±28.05   290.36±31.96   302.27±32.74 
CB4856   127.35±6.29    138.36±8.69    149.29±10.9  
RC301    132.47±13.53   113.76±9.99    124.26±10.77 
PD1074   113.95±5.71    125.91±7.83    135.98±9.95  
ECA248   86.06±4.61     94.06±5.71     97.15±6.63   
ECA36    105.31±2.6     112.07±5.17    114.49±6.19  
ECA396   126±11.04      108.5±7.86     116.76±8.2   


Table: Paraquat Estimates

Strain   Weibull          Log-Logistic     Lognormal      
-------  ---------------  ---------------  ---------------
MY16     260.88±26.76     558.39±99.17     694.04±118.65  
XZ1516   1028.95±140.69   1472.55±311.42   1559.55±320.79 
CB4856   264.81±25.8      471.32±74.8      564.83±99.15   
RC301    515.82±96.76     572.24±118.93    676.16±128.82  
PD1074   269.52±29.21     518.5±83.42      621.42±110.72  
ECA248   171.73±23.93     307.92±49.24     331.75±57.85   
ECA36    157.05±6.09      271.17±37.15     285.56±44.67   
ECA396   489.11±80.73     543.61±93.74     624.93±97.74   


Table: Propoxur Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
PD1074   102.71±17.64   128.4±18.79    135.24±17.89 
CB4856   204.62±27.23   227.04±26.01   229.08±24.5  
ECA36    147±24.67      172.88±24.52   174.54±23.12 
MY16     129.82±15.09   146.53±15.24   148.41±14.36 
ECA396   97.45±18.41    121.89±18.14   126.27±17.17 
RC301    85.92±11.72    103.31±11.88   108.98±11.35 
XZ1516   156.32±21.94   182.46±20.94   185.29±19.86 


Table: Propoxur Estimates

Strain   Weibull        Log-Logistic   Lognormal    
-------  -------------  -------------  -------------
PD1074   462.46±37.45   445.04±41.43   432.96±37.42 
CB4856   494.38±28.99   472.34±29.93   468.21±28.86 
ECA36    454.63±31.42   438.07±32.39   431.67±31.38 
MY16     367.86±17.6    359.19±19.56   352.43±18.96 
ECA396   353.17±31.85   336.68±31.64   334.18±29.93 
RC301    367.75±22.54   361.68±25.85   352.48±23.76 
XZ1516   407.88±25.76   388.23±25.26   386.84±24.42 


Table: Propoxur Estimates

Strain   Weibull          Log-Logistic     Lognormal      
-------  ---------------  ---------------  ---------------
PD1074   1206.49±150.61   1542.49±324.65   1386.09±248.18 
CB4856   867.38±76.98     982.68±122.49    956.97±109.58  
ECA36    933.57±107.49    1110.02±175.15   1067.6±151.52  
MY16     714.39±54.4      880.49±102.47    836.9±89.71    
ECA396   802.36±124.64    929.94±196.43    884.42±164.17  
RC301    928.94±98.21     1266.21±212.74   1140.01±168.61 
XZ1516   751.59±75.68     826.03±110       807.61±97.65   


Table: Pyraclostrobin Estimates

Strain   Weibull      Log-Logistic   Lognormal  
-------  -----------  -------------  -----------
ECA396   6.18±0.49    7.87±0.54      8.1±0.54   
CB4856   11.33±1.17   14.6±1.33      15.17±1.34 
ECA36    11.69±0.76   15.1±0.83      15.61±0.84 
MY16     6.27±0.64    8.3±0.73       8.61±0.72  
XZ1516   10.13±0.94   12.96±1.09     13.46±1.1  
RC301    17.2±1.73    20.95±1.8      21.21±1.75 
PD1074   11.54±0.81   14.59±0.88     15.02±0.87 
ECA248   7.44±1.32    9.97±1.58      10.46±1.63 


Table: Pyraclostrobin Estimates

Strain   Weibull      Log-Logistic   Lognormal   
-------  -----------  -------------  ------------
ECA396   48.26±2.65   53.21±3.83     52.87±4.13  
CB4856   92.21±5.58   97.62±7.71     94.95±7.69  
ECA36    80.24±2.75   80.93±3.1      79.45±3.06  
MY16     78.05±5.14   88.98±8.6      87.29±9.3   
XZ1516   91.98±5.05   98.61±7.51     95.05±7.48  
RC301    93.35±5.32   92.68±5.85     91.25±5.7   
PD1074   90.98±3.86   95.22±5.14     93.2±5.18   
ECA248   84.34±8.54   94.74±14.1     91.76±14.69 


Table: Pyraclostrobin Estimates

Strain   Weibull        Log-Logistic    Lognormal     
-------  -------------  --------------  --------------
ECA396   178.78±17.31   359.66±57.36    344.86±57.91  
CB4856   350.79±37.16   652.66±119.51   594.23±109.27 
ECA36    273.83±17.68   433.65±41.22    404.21±37.17  
MY16     389.34±44.23   954.14±202.68   884.91±201.53 
XZ1516   375.23±35.02   750.37±130.27   671.09±117.68 
RC301    274.28±28.05   409.95±59.33    392.61±54.16  
PD1074   339.15±25.17   621.44±76.28    578.39±71.12  
ECA248   396.3±70.87    899.95±313.7    804.61±296.75 


Table: Silver nitrate Estimates

Strain   Weibull       Log-Logistic   Lognormal   
-------  ------------  -------------  ------------
MY16     3.69±4.89     8.63±11.06     NA          
XZ1516   11.97±3.99    19.85±7.85     48.47±43.59 
ECA36    53.67±65.92   NA             NA          


Table: Silver nitrate Estimates

Strain   Weibull        Log-Logistic   Lognormal 
-------  -------------  -------------  ----------
XZ1516   184.95±87.98   NA             NA        


Table: Triphenyl phosphate Estimates

Strain   Weibull     Log-Logistic   Lognormal 
-------  ----------  -------------  ----------
ECA396   1.74±0.14   2.22±0.16      2.3±0.16  
CB4856   2.39±0.24   2.98±0.27      3.12±0.29 
ECA36    2.54±0.31   3.17±0.35      3.29±0.37 
MY16     0.49±0.07   0.71±0.08      0.77±0.08 
XZ1516   4.11±0.63   4.9±0.68       5.09±0.7  
RC301    1.1±0.18    1.49±0.21      1.57±0.22 
PD1074   3.86±0.35   4.47±0.37      4.58±0.36 
ECA248   1.56±0.16   2.02±0.18      2.1±0.18  


Table: Triphenyl phosphate Estimates

Strain   Weibull      Log-Logistic   Lognormal  
-------  -----------  -------------  -----------
ECA396   17.38±0.98   21.94±2.1      22.37±2.72 
CB4856   19.96±1.12   23.47±2.25     22.57±2.47 
ECA36    20.15±1.26   23.67±2.51     23.13±2.87 
MY16     11.81±1.18   17.73±3.3      18.67±4.53 
XZ1516   21.57±1.62   22.83±2.35     22.05±2.3  
RC301    15.76±1.67   21.97±4.53     23.04±6.53 
PD1074   19.98±0.91   20.89±1.29     20.17±1.27 
ECA248   17.13±1.13   21.42±2.4      21.79±3.08 


Table: Triphenyl phosphate Estimates

Strain   Weibull       Log-Logistic   Lognormal    
-------  ------------  -------------  -------------
ECA396   75.36±7.25    NA             NA           
CB4856   77.07±7.48    184.97±40.27   163.42±40.1  
ECA36    75.37±8.99    176.65±45.46   162.36±47.94 
MY16     89.87±15.5    NA             NA           
XZ1516   62.06±8.37    106.33±26.68   95.58±24.03  
RC301    85.87±16.45   NA             NA           
PD1074   56.97±4.53    97.55±14.14    88.93±12.82  
ECA248   79±9.24       NA             NA           


Table: 2,4-D Estimates

Strain   Weibull         Log-Logistic    Lognormal     
-------  --------------  --------------  --------------
ECA36    606.32±203.47   701.36±284.54   NA            
MY16     661.03±36.12    695.26±50.26    739.65±119.32 
ECA396   442.68±38.97    521.7±80.49     787.12±567.66 
ECA248   600.54±30.33    615.09±26.92    614.75±26.56  


Table: 2,4-D Estimates

Strain   Weibull         Log-Logistic    Lognormal   
-------  --------------  --------------  ------------
MY16     895.94±78.73    969.37±122.66   NA          
ECA396   845.75±135.01   NA              NA          
ECA248   777.13±26.9     805.09±49.74    817.2±75.29 


Table: 2,4-D Estimates

Strain   Weibull        Log-Logistic   Lognormal 
-------  -------------  -------------  ----------
ECA248   915.87±53.67   NA             NA        


Table: Zinc dichloride Estimates

Strain   Weibull       Log-Logistic   Lognormal   
-------  ------------  -------------  ------------
MY16     51.08±2.82    64.58±5.12     83.07±19.79 
XZ1516   52.16±3.55    64.9±5.84      77.48±16.39 
PD1074   77.82±16.89   120.54±36.25   NA          
ECA36    80.79±25.96   121.61±50.47   NA          
ECA396   35.12±1.72    41.24±1.71     43.03±1.98  
RC301    49.1±3.08     59.8±4.33      69.49±11.07 
ECA248   51.52±3.26    62.76±4.68     72.95±12.87 
CB4856   59.86±18.14   104.2±46.83    NA          


Table: Zinc dichloride Estimates

Strain   Weibull         Log-Logistic   Lognormal     
-------  --------------  -------------  --------------
MY16     197.78±19.81    289.39±53.79   NA            
XZ1516   199.17±23.09    278.8±57.38    NA            
PD1074   370.82±116.33   NA             NA            
ECA36    391.12±177.37   NA             NA            
ECA396   137.47±5.6      170.3±13.87    193.37±26.96  
RC301    183.65±16.31    250.99±40.75   371.7±135.69  
ECA248   186.36±17.6     254.84±45.6    368.98±155.29 
CB4856   364.74±162.68   NA             NA            


Table: Zinc dichloride Estimates

Strain   Weibull        Log-Logistic   Lognormal 
-------  -------------  -------------  ----------
ECA396   328.05±23.34   NA             NA        
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sessionInfo()
R version 4.0.4 (2021-02-15)
Platform: x86_64-apple-darwin17.0 (64-bit)
Running under: macOS Catalina 10.15.7

Matrix products: default
BLAS:   /Library/Frameworks/R.framework/Versions/4.0/Resources/lib/libRblas.dylib
LAPACK: /Library/Frameworks/R.framework/Versions/4.0/Resources/lib/libRlapack.dylib

locale:
[1] en_US.UTF-8/en_US.UTF-8/en_US.UTF-8/C/en_US.UTF-8/en_US.UTF-8

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
 [1] RColorBrewer_1.1-2 RCurl_1.98-1.2     ddpcr_1.15         kableExtra_1.3.4  
 [5] knitr_1.31         drc_3.0-1          MASS_7.3-53        easyXpress_0.1.0  
 [9] forcats_0.5.1      stringr_1.4.0      dplyr_1.0.4        purrr_0.3.4       
[13] readr_1.4.0        tidyr_1.1.2        tibble_3.1.0       ggplot2_3.3.3     
[17] tidyverse_1.3.0    workflowr_1.6.2   

loaded via a namespace (and not attached):
  [1] TH.data_1.0-10        colorspace_2.0-0      ellipsis_0.3.1       
  [4] rio_0.5.16            rprojroot_2.0.2       fs_1.5.0             
  [7] rstudioapi_0.13       farver_2.0.3          fansi_0.4.2          
 [10] mvtnorm_1.1-1         lubridate_1.7.9.2     xml2_1.3.2           
 [13] codetools_0.2-18      splines_4.0.4         readbitmap_0.1.5     
 [16] jsonlite_1.7.2        broom_0.7.5           dbplyr_2.1.0         
 [19] png_0.1-7             compiler_4.0.4        httr_1.4.2           
 [22] backports_1.2.1       assertthat_0.2.1      bmp_0.3              
 [25] Matrix_1.3-2          cli_2.3.1             later_1.1.0.1        
 [28] htmltools_0.5.1.1     tools_4.0.4           igraph_1.2.6         
 [31] gtable_0.3.0          glue_1.4.2            rebus.base_0.0-3     
 [34] Rcpp_1.0.6            carData_3.0-4         cellranger_1.1.0     
 [37] jquerylib_0.1.3       vctrs_0.3.6           svglite_2.0.0        
 [40] xfun_0.21             rebus.datetimes_0.0-1 openxlsx_4.2.3       
 [43] rvest_0.3.6           lifecycle_1.0.0       rebus.numbers_0.0-1  
 [46] gtools_3.8.2          zoo_1.8-8             scales_1.1.1         
 [49] hms_1.0.0             promises_1.2.0.1      sandwich_3.0-0       
 [52] yaml_2.2.1            curl_4.3              sass_0.3.1           
 [55] stringi_1.5.3         imager_0.42.7         highr_0.8            
 [58] plotrix_3.8-1         tiff_0.1-6            zip_2.1.1            
 [61] bitops_1.0-6          rlang_0.4.10          pkgconfig_2.0.3      
 [64] systemfonts_1.0.1     evaluate_0.14         lattice_0.20-41      
 [67] labeling_0.4.2        cowplot_1.1.1         tidyselect_1.1.0     
 [70] magrittr_2.0.1        R6_2.5.0              generics_0.1.0       
 [73] multcomp_1.4-16       DBI_1.1.1             pillar_1.5.0         
 [76] haven_2.3.1           whisker_0.4           foreign_0.8-81       
 [79] withr_2.4.1           rebus_0.1-3           survival_3.2-7       
 [82] abind_1.4-5           rebus.unicode_0.0-2   modelr_0.1.8         
 [85] crayon_1.4.1          car_3.0-10            utf8_1.1.4           
 [88] rmarkdown_2.7         jpeg_0.1-8.1          grid_4.0.4           
 [91] readxl_1.3.1          data.table_1.14.0     git2r_0.28.0         
 [94] reprex_1.0.0          digest_0.6.27         webshot_0.5.2        
 [97] httpuv_1.5.5          munsell_0.5.0         viridisLite_0.3.0    
[100] bslib_0.2.4